LOCUS       DAVFJR010000001       179535 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVFJR010000001 DAVFJR010000000
VERSION     DAVFJR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 179535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 179535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..179535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.001"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            41..439
                     /gene="spx"
                     /locus_tag="VU722_000001"
     CDS             41..439
                     /gene="spx"
                     /locus_tag="VU722_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU1771076.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            505..1074
                     /locus_tag="VU722_000002"
     CDS             505..1074
                     /locus_tag="VU722_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1771077.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGSATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            1161..1427
                     /locus_tag="VU722_000003"
     CDS             1161..1427
                     /locus_tag="VU722_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU1771078.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            1431..1850
                     /gene="ruvX"
                     /locus_tag="VU722_000004"
     CDS             1431..1850
                     /gene="ruvX"
                     /locus_tag="VU722_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU1771079.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            1866..2171
                     /locus_tag="VU722_000005"
     CDS             1866..2171
                     /locus_tag="VU722_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU1771080.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            2478..3728
                     /locus_tag="VU722_000006"
     CDS             2478..3728
                     /locus_tag="VU722_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU1771081.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            3725..4270
                     /locus_tag="VU722_000007"
     CDS             3725..4270
                     /locus_tag="VU722_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU1771082.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKSIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            4416..5948
                     /gene="cls"
                     /locus_tag="VU722_000008"
     CDS             4416..5948
                     /gene="cls"
                     /locus_tag="VU722_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU1771083.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            6026..6169
                     /locus_tag="VU722_000009"
     CDS             6026..6169
                     /locus_tag="VU722_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771084.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            6206..7744
                     /locus_tag="VU722_000010"
     CDS             6206..7744
                     /locus_tag="VU722_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU1771085.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSFLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            7864..10071
                     /gene="nrdD"
                     /locus_tag="VU722_000011"
     CDS             7864..10071
                     /gene="nrdD"
                     /locus_tag="VU722_000011"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU1771086.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLDDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            10083..10223
                     /locus_tag="VU722_000012"
     CDS             10083..10223
                     /locus_tag="VU722_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771087.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            10267..10773
                     /locus_tag="VU722_000013"
     CDS             10267..10773
                     /locus_tag="VU722_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771088.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            10766..11356
                     /gene="nrdG"
                     /locus_tag="VU722_000014"
     CDS             10766..11356
                     /gene="nrdG"
                     /locus_tag="VU722_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU1771089.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            11353..11970
                     /locus_tag="VU722_000015"
     CDS             11353..11970
                     /locus_tag="VU722_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU1771090.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            12237..12545
                     /gene="rpsJ"
                     /locus_tag="VU722_000016"
     CDS             12237..12545
                     /gene="rpsJ"
                     /locus_tag="VU722_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU1771091.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            12762..13388
                     /gene="rplC"
                     /locus_tag="VU722_000017"
     CDS             12762..13388
                     /gene="rplC"
                     /locus_tag="VU722_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU1771092.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            13413..14036
                     /gene="rplD"
                     /locus_tag="VU722_000018"
     CDS             13413..14036
                     /gene="rplD"
                     /locus_tag="VU722_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU1771093.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            14036..14332
                     /locus_tag="VU722_000019"
     CDS             14036..14332
                     /locus_tag="VU722_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU1771094.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            14350..15183
                     /gene="rplB"
                     /locus_tag="VU722_000020"
     CDS             14350..15183
                     /gene="rplB"
                     /locus_tag="VU722_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU1771095.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSCWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            15287..15568
                     /gene="rpsS"
                     /locus_tag="VU722_000021"
     CDS             15287..15568
                     /gene="rpsS"
                     /locus_tag="VU722_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU1771096.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            15580..15924
                     /gene="rplV"
                     /locus_tag="VU722_000022"
     CDS             15580..15924
                     /gene="rplV"
                     /locus_tag="VU722_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU1771097.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            15937..16590
                     /gene="rpsC"
                     /locus_tag="VU722_000023"
     CDS             15937..16590
                     /gene="rpsC"
                     /locus_tag="VU722_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU1771098.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            16594..17007
                     /gene="rplP"
                     /locus_tag="VU722_000024"
     CDS             16594..17007
                     /gene="rplP"
                     /locus_tag="VU722_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU1771099.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            17017..17223
                     /locus_tag="VU722_000025"
     CDS             17017..17223
                     /locus_tag="VU722_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU1771100.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTVRLKEVKKQIARIKTVQSEAK"
     gene            17248..17508
                     /gene="rpsQ"
                     /locus_tag="VU722_000026"
     CDS             17248..17508
                     /gene="rpsQ"
                     /locus_tag="VU722_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU1771101.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            17534..17902
                     /gene="rplN"
                     /locus_tag="VU722_000027"
     CDS             17534..17902
                     /gene="rplN"
                     /locus_tag="VU722_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU1771102.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            17980..18285
                     /gene="rplX"
                     /locus_tag="VU722_000028"
     CDS             17980..18285
                     /gene="rplX"
                     /locus_tag="VU722_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU1771103.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            18309..18851
                     /gene="rplE"
                     /locus_tag="VU722_000029"
     CDS             18309..18851
                     /gene="rplE"
                     /locus_tag="VU722_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU1771104.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            18869..19138
                     /gene="rpsN"
                     /locus_tag="VU722_000030"
     CDS             18869..19138
                     /gene="rpsN"
                     /locus_tag="VU722_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU1771105.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            19352..19750
                     /gene="rpsH"
                     /locus_tag="VU722_000031"
     CDS             19352..19750
                     /gene="rpsH"
                     /locus_tag="VU722_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU1771106.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            19942..20478
                     /gene="rplF"
                     /locus_tag="VU722_000032"
     CDS             19942..20478
                     /gene="rplF"
                     /locus_tag="VU722_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU1771107.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VDGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            20562..20918
                     /gene="rplR"
                     /locus_tag="VU722_000033"
     CDS             20562..20918
                     /gene="rplR"
                     /locus_tag="VU722_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU1771108.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            20936..21430
                     /gene="rpsE"
                     /locus_tag="VU722_000034"
     CDS             20936..21430
                     /gene="rpsE"
                     /locus_tag="VU722_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU1771109.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            21402..21626
                     /gene="rpmD"
                     /locus_tag="VU722_000035"
     CDS             21402..21626
                     /gene="rpmD"
                     /locus_tag="VU722_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU1771110.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            21771..22211
                     /gene="rplO"
                     /locus_tag="VU722_000036"
     CDS             21771..22211
                     /gene="rplO"
                     /locus_tag="VU722_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU1771111.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            22224..23534
                     /gene="secY"
                     /locus_tag="VU722_000037"
     CDS             22224..23534
                     /gene="secY"
                     /locus_tag="VU722_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU1771112.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDKTE"
     gene            23685..24323
                     /locus_tag="VU722_000038"
     CDS             23685..24323
                     /locus_tag="VU722_000038"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU1771113.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            24440..24658
                     /gene="infA"
                     /locus_tag="VU722_000039"
     CDS             24440..24658
                     /gene="infA"
                     /locus_tag="VU722_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU1771114.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            24683..24799
                     /gene="rpmJ"
                     /locus_tag="VU722_000040"
     CDS             24683..24799
                     /gene="rpmJ"
                     /locus_tag="VU722_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU1771115.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            24817..25182
                     /gene="rpsM"
                     /locus_tag="VU722_000041"
     CDS             24817..25182
                     /gene="rpsM"
                     /locus_tag="VU722_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU1771116.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            25200..25583
                     /gene="rpsK"
                     /locus_tag="VU722_000042"
     CDS             25200..25583
                     /gene="rpsK"
                     /locus_tag="VU722_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU1771117.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            25626..26561
                     /locus_tag="VU722_000043"
     CDS             25626..26561
                     /locus_tag="VU722_000043"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU1771118.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            26573..26959
                     /gene="rplQ"
                     /locus_tag="VU722_000044"
     CDS             26573..26959
                     /gene="rplQ"
                     /locus_tag="VU722_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU1771119.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            27224..27490
                     /locus_tag="VU722_000045"
     CDS             27224..27490
                     /locus_tag="VU722_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU1771120.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            27500..28837
                     /locus_tag="VU722_000046"
     CDS             27500..28837
                     /locus_tag="VU722_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU1771121.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSAVVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            29081..29773
                     /locus_tag="VU722_000047"
     CDS             29081..29773
                     /locus_tag="VU722_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1771122.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEGGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(29876..31521)
                     /locus_tag="VU722_000048"
                     /pseudo
     CDS             complement(29876..31521)
                     /locus_tag="VU722_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(31511..31816)
                     /locus_tag="VU722_000049"
                     /pseudo
     CDS             complement(31511..31816)
                     /locus_tag="VU722_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(31952..32589)
                     /locus_tag="VU722_000050"
                     /pseudo
     CDS             complement(31952..32589)
                     /locus_tag="VU722_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(32602..33723)
                     /locus_tag="VU722_000051"
                     /pseudo
     CDS             complement(32602..33723)
                     /locus_tag="VU722_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(33941..34138)
                     /locus_tag="VU722_000052"
     CDS             complement(33941..34138)
                     /locus_tag="VU722_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU1771123.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(34213..34989)
                     /locus_tag="VU722_000053"
     CDS             complement(34213..34989)
                     /locus_tag="VU722_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU1771124.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            35111..35857
                     /locus_tag="VU722_000054"
     CDS             35111..35857
                     /locus_tag="VU722_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1771125.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            35870..36850
                     /locus_tag="VU722_000055"
     CDS             35870..36850
                     /locus_tag="VU722_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU1771126.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            37045..37365
                     /locus_tag="VU722_000056"
     CDS             37045..37365
                     /locus_tag="VU722_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1771127.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            37411..37719
                     /locus_tag="VU722_000057"
     CDS             37411..37719
                     /locus_tag="VU722_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1771128.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            37736..39034
                     /locus_tag="VU722_000058"
     CDS             37736..39034
                     /locus_tag="VU722_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU1771129.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            39185..41623
                     /locus_tag="VU722_000059"
     CDS             39185..41623
                     /locus_tag="VU722_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU1771130.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELELFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDSASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            41642..42310
                     /locus_tag="VU722_000060"
     CDS             41642..42310
                     /locus_tag="VU722_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU1771131.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            42328..43416
                     /locus_tag="VU722_000061"
     CDS             42328..43416
                     /locus_tag="VU722_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU1771132.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            43871..46372
                     /locus_tag="VU722_000062"
     CDS             43871..46372
                     /locus_tag="VU722_000062"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU1771133.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLTAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLIEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            46566..47261
                     /locus_tag="VU722_000063"
     CDS             46566..47261
                     /locus_tag="VU722_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771134.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            47273..47689
                     /locus_tag="VU722_000064"
     CDS             47273..47689
                     /locus_tag="VU722_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771135.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(48517..48609)
                     /locus_tag="VU722_000065"
     CDS             complement(48517..48609)
                     /locus_tag="VU722_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU1771136.1"
                     /translation="MMELILKTIIGPIVVGVVLRLVDKWLNKDR"
     gene            complement(48950..49042)
                     /locus_tag="VU722_000066"
     CDS             complement(48950..49042)
                     /locus_tag="VU722_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU1771137.1"
                     /translation="MMDTILKTIIGPIVVGVVLRLVDKWLNKDK"
     gene            complement(49357..49449)
                     /locus_tag="VU722_000067"
     CDS             complement(49357..49449)
                     /locus_tag="VU722_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU1771138.1"
                     /translation="MMELVLKTIIGPFVVGVVLRLVDKWLNKDK"
     gene            49609..50580
                     /gene="ruvB"
                     /locus_tag="VU722_000068"
     CDS             49609..50580
                     /gene="ruvB"
                     /locus_tag="VU722_000068"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU1771139.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRMATAKAYEHLGYEYNEK"
     gene            50561..51133
                     /locus_tag="VU722_000069"
     CDS             50561..51133
                     /locus_tag="VU722_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU1771140.1"
                     /translation="MSTMKNKQEILESFRKNPDMMAILTIIQNLELTDSWLAAGSVRN
                     FIWNLLSDKSPFDFETDVDVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTAPYTSSRDAMSKYPERCTAVGLRLNEEPALELFTPYGLEDILNFQVRPTPHFL
                     ENQERMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            51364..52122
                     /locus_tag="VU722_000070"
     CDS             51364..52122
                     /locus_tag="VU722_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU1771141.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEVALQEAILAYNRRHRRFGGV"
     gene            52131..52934
                     /locus_tag="VU722_000071"
     CDS             52131..52934
                     /locus_tag="VU722_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU1771142.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            52956..54215
                     /gene="rseP"
                     /locus_tag="VU722_000072"
     CDS             52956..54215
                     /gene="rseP"
                     /locus_tag="VU722_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU1771143.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            54228..56081
                     /locus_tag="VU722_000073"
     CDS             54228..56081
                     /locus_tag="VU722_000073"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU1771144.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            56180..57559
                     /gene="bglA"
                     /locus_tag="VU722_000074"
     CDS             56180..57559
                     /gene="bglA"
                     /locus_tag="VU722_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU1771145.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVLAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            57752..59560
                     /gene="glmS"
                     /locus_tag="VU722_000075"
     CDS             57752..59560
                     /gene="glmS"
                     /locus_tag="VU722_000075"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU1771146.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDSNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEVGQ
                     VVVDQAIIQAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANHTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLTLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKETDAIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            60005..61774
                     /locus_tag="VU722_000076"
     CDS             60005..61774
                     /locus_tag="VU722_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU1771147.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGSLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMLIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDISTSASVDSQEIDFNHIDAVVVAYGKAQ
                     GSATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQTAPNS
                     QFLIVDSLVTTPEYDKMAVRMYK"
     gene            61798..63753
                     /locus_tag="VU722_000077"
     CDS             61798..63753
                     /locus_tag="VU722_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1771148.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECMKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            63755..64192
                     /locus_tag="VU722_000078"
     CDS             63755..64192
                     /locus_tag="VU722_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1771149.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            64254..65390
                     /locus_tag="VU722_000079"
     CDS             64254..65390
                     /locus_tag="VU722_000079"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU1771150.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKSGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLITKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDPELIEQIVEYI"
     gene            65642..66691
                     /locus_tag="VU722_000080"
                     /pseudo
     CDS             65642..66691
                     /locus_tag="VU722_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
     gene            complement(66791..70561)
                     /gene="spuA"
                     /locus_tag="VU722_000081"
     CDS             complement(66791..70561)
                     /gene="spuA"
                     /locus_tag="VU722_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU1771151.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDATSIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEVHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVRNESV
                     ENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            70848..72194
                     /locus_tag="VU722_000082"
     CDS             70848..72194
                     /locus_tag="VU722_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU1771152.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVANMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            72686..73099
                     /gene="rpsL"
                     /locus_tag="VU722_000083"
     CDS             72686..73099
                     /gene="rpsL"
                     /locus_tag="VU722_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU1771153.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            73119..73589
                     /gene="rpsG"
                     /locus_tag="VU722_000084"
     CDS             73119..73589
                     /gene="rpsG"
                     /locus_tag="VU722_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU1771154.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            74014..76095
                     /gene="fusA"
                     /locus_tag="VU722_000085"
     CDS             74014..76095
                     /gene="fusA"
                     /locus_tag="VU722_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU1771155.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            76199..80590
                     /locus_tag="VU722_000086"
     CDS             76199..80590
                     /locus_tag="VU722_000086"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU1771156.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            80692..80955
                     /locus_tag="VU722_000087"
     CDS             80692..80955
                     /locus_tag="VU722_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU1771157.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            80948..81226
                     /locus_tag="VU722_000088"
     CDS             80948..81226
                     /locus_tag="VU722_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU1771158.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            81247..81399
                     /locus_tag="VU722_000089"
     CDS             81247..81399
                     /locus_tag="VU722_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771159.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            81421..82662
                     /locus_tag="VU722_000090"
     CDS             81421..82662
                     /locus_tag="VU722_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU1771160.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            82672..82902
                     /locus_tag="VU722_000091"
     CDS             82672..82902
                     /locus_tag="VU722_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU1771161.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            83170..83892
                     /locus_tag="VU722_000092"
     CDS             83170..83892
                     /locus_tag="VU722_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU1771162.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            84109..85443
                     /gene="pepC"
                     /locus_tag="VU722_000093"
     CDS             84109..85443
                     /gene="pepC"
                     /locus_tag="VU722_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU1771163.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(85499..86410)
                     /locus_tag="VU722_000094"
     CDS             complement(85499..86410)
                     /locus_tag="VU722_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1771164.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(86434..87237)
                     /locus_tag="VU722_000095"
     CDS             complement(86434..87237)
                     /locus_tag="VU722_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU1771165.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(87265..88254)
                     /gene="manX"
                     /locus_tag="VU722_000096"
     CDS             complement(87265..88254)
                     /gene="manX"
                     /locus_tag="VU722_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU1771166.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(88487..89506)
                     /gene="adhP"
                     /locus_tag="VU722_000097"
     CDS             complement(88487..89506)
                     /gene="adhP"
                     /locus_tag="VU722_000097"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU1771167.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(89845..90657)
                     /locus_tag="VU722_000098"
     CDS             complement(89845..90657)
                     /locus_tag="VU722_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1771168.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            90847..92265
                     /locus_tag="VU722_000099"
     CDS             90847..92265
                     /locus_tag="VU722_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU1771169.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            92318..93025
                     /locus_tag="VU722_000100"
     CDS             92318..93025
                     /locus_tag="VU722_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1771170.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTVVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVILSRTLGISV"
     gene            93119..94096
                     /gene="folP"
                     /locus_tag="VU722_000101"
     CDS             93119..94096
                     /gene="folP"
                     /locus_tag="VU722_000101"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU1771171.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGRSSYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVIARPQHPSSL
                     IFPHFGFGQAFTEKELADFETLPIEDLMETFFDRALARAEEAGIAQENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTA
                     SAHVTSIAVRQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            94098..95420
                     /locus_tag="VU722_000102"
     CDS             94098..95420
                     /locus_tag="VU722_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU1771172.1"
                     /translation="MKEFENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     RSLLEGESATNLQGTTEFEIITAIAYDYFALEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGTPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            95401..95955
                     /gene="folE"
                     /locus_tag="VU722_000103"
     CDS             95401..95955
                     /gene="folE"
                     /locus_tag="VU722_000103"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU1771173.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            95998..96810
                     /gene="folB"
                     /locus_tag="VU722_000104"
     CDS             95998..96810
                     /gene="folB"
                     /locus_tag="VU722_000104"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEU1771174.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFETYPLVQEIKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLEQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVIEVETWLPAPVLLETLLAIESEMGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIASHFIHPTLKQPIRNLYNALKK"
     gene            complement(96855..97172)
                     /locus_tag="VU722_000105"
     CDS             complement(96855..97172)
                     /locus_tag="VU722_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU1771175.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPLYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            97529..97975
                     /gene="rplM"
                     /locus_tag="VU722_000106"
     CDS             97529..97975
                     /gene="rplM"
                     /locus_tag="VU722_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU1771176.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            97995..98387
                     /gene="rpsI"
                     /locus_tag="VU722_000107"
     CDS             97995..98387
                     /gene="rpsI"
                     /locus_tag="VU722_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU1771177.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(98649..99071)
                     /locus_tag="VU722_000108"
     CDS             complement(98649..99071)
                     /locus_tag="VU722_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1771178.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            99218..99394
                     /locus_tag="VU722_000109"
     CDS             99218..99394
                     /locus_tag="VU722_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771179.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            99796..102009
                     /locus_tag="VU722_000110"
     CDS             99796..102009
                     /locus_tag="VU722_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU1771180.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHCYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(102231..102707)
                     /locus_tag="VU722_000111"
     CDS             complement(102231..102707)
                     /locus_tag="VU722_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU1771181.1"
                     /translation="MTSLYDFSFLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            102930..105959
                     /locus_tag="VU722_000112"
                     /pseudo
     CDS             102930..105959
                     /locus_tag="VU722_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884539.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            106017..106133
                     /locus_tag="VU722_000113"
                     /pseudo
     CDS             106017..106133
                     /locus_tag="VU722_000113"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            106514..106890
                     /gene="tnpA"
                     /locus_tag="VU722_000114"
                     /pseudo
     CDS             106514..106890
                     /gene="tnpA"
                     /locus_tag="VU722_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(107277..107906)
                     /locus_tag="VU722_000115"
     CDS             complement(107277..107906)
                     /locus_tag="VU722_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU1771182.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNPYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(107916..108917)
                     /locus_tag="VU722_000116"
     CDS             complement(107916..108917)
                     /locus_tag="VU722_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU1771183.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGYRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFVRFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(108948..109589)
                     /locus_tag="VU722_000117"
     CDS             complement(108948..109589)
                     /locus_tag="VU722_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU1771184.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     NPLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVVPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(109608..110423)
                     /locus_tag="VU722_000118"
     CDS             complement(109608..110423)
                     /locus_tag="VU722_000118"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU1771185.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEVGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASDFVNGHILYVDGGILAYIGKQPE"
     gene            110694..111128
                     /locus_tag="VU722_000119"
     CDS             110694..111128
                     /locus_tag="VU722_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1771186.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            111140..112330
                     /locus_tag="VU722_000120"
     CDS             111140..112330
                     /locus_tag="VU722_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU1771187.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVDQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDEFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYVSANNVIRDDASSFHT
                     FYFDPETGQPLKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            112341..112832
                     /locus_tag="VU722_000121"
     CDS             112341..112832
                     /locus_tag="VU722_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU1771188.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGGEDKAALKELNQTYQVTFNTKTTPTGNDGAVEVNIM
                     DYI"
     gene            112847..113626
                     /locus_tag="VU722_000122"
     CDS             112847..113626
                     /locus_tag="VU722_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU1771189.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            113613..114431
                     /locus_tag="VU722_000123"
     CDS             113613..114431
                     /locus_tag="VU722_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1771190.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADTKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKILA"
     gene            114431..114724
                     /gene="yajC"
                     /locus_tag="VU722_000124"
     CDS             114431..114724
                     /gene="yajC"
                     /locus_tag="VU722_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU1771191.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRKEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            114746..116647
                     /locus_tag="VU722_000125"
     CDS             114746..116647
                     /locus_tag="VU722_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU1771192.1"
                     /translation="MKEERRQFFEKIDGDQYRDYILSHCSQDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWNQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFRPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEEELENIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPILATYHFFSDKMDLEEAYHFASKELKQQ
                     IETQILEDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSFQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAMVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFRSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDT
                     GRYSYREVDERYLLKSAWSHSTCIVDGKAPERIVGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYLSAEPDLPYLHRRKILMLAEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLKLWSEVDFDLEATIISPKYNELEKSSKLIKHQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDGHQVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            116707..117708
                     /locus_tag="VU722_000126"
     CDS             116707..117708
                     /locus_tag="VU722_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1771193.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIKKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSTQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSRLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHARLT
                     IEDKHTNLEQIKEFLQKEINPDEKTLVFVPNCWALPPVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPAFEEGQQATKILIDQIEGLNQEERQQVLDCSVSWKESTF"
     gene            complement(117979..118557)
                     /locus_tag="VU722_000127"
     CDS             complement(117979..118557)
                     /locus_tag="VU722_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU1771194.1"
                     /translation="MKKEDLTTRLLRNLFHIQGPFDECRQEIIYKACARSMVQIVYSS
                     FFLFLFYLLFGRFIEAVRYAMPYVYSGLIFFITLKTQRVVKELHMEKDDKSEIILKTY
                     SKAQIKFRSWIVFIGLQIGLFTLLIFHKVFVQQMSLSDFVKLLMQFDKSVPFLMYGLI
                     IGSIFGTLTYGFLSLQEEKIPKNTKQKEKSKQ"
     gene            complement(118584..118907)
                     /locus_tag="VU722_000128"
     CDS             complement(118584..118907)
                     /locus_tag="VU722_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771195.1"
                     /translation="MKSLLTLLTYHLLFSSLLIFIIVSGNLIREIFLVLVFVPALNKV
                     LTYLKIDSPKTRTLNLALYFMILSFPQLMLVSGNWNYYLLLTIASLSSIIYLYYLYQF
                     VKENQ"
     gene            complement(118918..119160)
                     /locus_tag="VU722_000129"
     CDS             complement(118918..119160)
                     /locus_tag="VU722_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771196.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVILFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(119171..119713)
                     /locus_tag="VU722_000130"
     CDS             complement(119171..119713)
                     /locus_tag="VU722_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU1771197.1"
                     /translation="MKKETFTEKLIKRTYGISDPLDEYKRREADRIGNQVFIFLFYLM
                     IFGNLIPLLLAYKYPQLVALVYPPLILVIALIVAGYLTYQMQKTGITTIEPDMLNEKE
                     SKQLHYPGLKAGIVYGLMSFFTTPLLHILLGESQDYLQSLLAFKNIFSSILQSVFFGV
                     VIQILISRRIAKARKNQDND"
     gene            complement(119724..120266)
                     /locus_tag="VU722_000131"
     CDS             complement(119724..120266)
                     /locus_tag="VU722_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU1771198.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKDQDED"
     gene            complement(120282..120476)
                     /locus_tag="VU722_000132"
     CDS             complement(120282..120476)
                     /locus_tag="VU722_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1771199.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            120643..121593
                     /gene="rsmH"
                     /locus_tag="VU722_000133"
     CDS             120643..121593
                     /gene="rsmH"
                     /locus_tag="VU722_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU1771200.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            121605..121922
                     /gene="ftsL"
                     /locus_tag="VU722_000134"
     CDS             121605..121922
                     /gene="ftsL"
                     /locus_tag="VU722_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU1771201.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            121926..124178
                     /locus_tag="VU722_000135"
     CDS             121926..124178
                     /locus_tag="VU722_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEU1771202.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAA
                     STTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            124180..125160
                     /locus_tag="VU722_000136"
     CDS             124180..125160
                     /locus_tag="VU722_000136"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU1771203.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIAAVVVSFLLALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            125817..127922
                     /locus_tag="VU722_000137"
     CDS             125817..127922
                     /locus_tag="VU722_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1771204.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLAGNAEVDGKMPQQPSGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEVGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     EAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGATDIERLKDMGHRLQTKVIGQDKAVEAVAKAIRRNRAGFDEGNRPIGSFLF
                     VGPTGVGKTELAKQLALDMFGTKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKEIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(128093..128575)
                     /locus_tag="VU722_000138"
     CDS             complement(128093..128575)
                     /locus_tag="VU722_000138"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU1771205.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAEIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(128670..130154)
                     /locus_tag="VU722_000139"
     CDS             complement(128670..130154)
                     /locus_tag="VU722_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU1771206.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGESPYA
                     SPTDMGVNMVGFAITDNEAAIEASKQEIIRRYYQTVLDFKAEKVSESAVKKIELLMND
                     LGITPSDRKVAVVARQKAEETGGPALALELPSGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPELVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            130307..131917
                     /locus_tag="VU722_000140"
     CDS             130307..131917
                     /locus_tag="VU722_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU1771207.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKNLLTVGETWGATPAIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVSMEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANPDSIFYTYKKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGTVKSV
                     LIENTTAQEVFEKQILAPWDAFCVELTD"
     gene            132187..134154
                     /locus_tag="VU722_000141"
     CDS             132187..134154
                     /locus_tag="VU722_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1771208.1"
                     /translation="MQSKKWLIGAGVTLSTAILLTACGKSEKNADAPKTFSYVYAVDP
                     SSLDYSLTSKSSTSDVIGNVVDGLLENDKYGNLIPSLAEDWSVSKDGLTYTYKLRKGV
                     KWYTSEGEEYAEVKAQDFVTGLKHAADGKSDGLSLVEKSIKGLEAYVSGETNDFSTVG
                     VKALDDYTVEYTLNNPESFWNSKVTTATMLPVNEEFLNATGKDYGAPTPSSILYNGPY
                     FLKSLISKSVIEYEKNPNYWDKDNVKIDNVKLTFYDGSDQESLIRSFTQGAYTTARLF
                     PASSNFESTKKEYGDKIVYSPQEATSYYLTVNVNRQSYNKTAKTDESQKTSTKEALLN
                     KNFRQALNFAFNRHAYTAQLNGEEGADKIIRNSLVPDNYVQVAGKTFGQLAQDELLKY
                     GEQWKDVTLTDGKDTIYNPTKAKSAFEKAKSELQAKGVSFPIHLDVPVEQTDVVAVQQ
                     TNSLKQSIEETLGTENVIIDVLQMTDNEKESITSQAKVPTQKDYDLNGTGWGPDYQDP
                     ATYLNILDAKKGSALKHLGITKGKDPEVVAKVGLDEYKKLLDDAASETSNLDKRYEKY
                     AKAQAWVTDSSLLIPVASSGGSPMVSRTVPFTKAYSQVGIKGDPFIFKGMELQNDIVT
                     TKEYDAAFKKWQKEKLESNAQYQKDLEKHIK"
     gene            134381..136339
                     /locus_tag="VU722_000142"
     CDS             134381..136339
                     /locus_tag="VU722_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1771209.1"
                     /translation="MTTKKRILSAGLTFAAALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNTAIITNLVDGLLENDNHGNLVPSLAEDWSVSSDGLTYTYKLRKDAKWF
                     TADGEEYAPVKAQDFVTGIKYAVDNKSQAIDLIQNSIKGLNDYITGADSDFSKVGVKA
                     IDDQTVEYTLTRPEPYWNSKTTNSILFPVNEEFLNSKGKDFGTLSPDSILYSGPYLLK
                     DFTSKSSIEYVKNPHYYDHDKVSIEHVKLAYFDGSDQELTIRNFESGAYSIAGVYPNS
                     SNFAKTKEKYKDNIVYSLQDKTSWYFNFNVNRKAYNHTSKTTDEQKKSTETAVLNKNF
                     RQAVNFALDRTAYSAQSNGEEAASKTLRNTLVPPTFVQVGDKTFGEVVASKLVNYGTE
                     WSGINLADAQDAYFNKEKAQAKFVEAKKELASQGVTFPIHLDVAVDQTSKNAVTGMNS
                     VKQTLESVLGADNVVIDVQQLSTDDFNNVAFLAPTAADRDYDLNFDGWVGDYQDPSTY
                     LNPFNAEDGFYLKIFGLDAKEDKEKITSLGLDTYTKMLKDADSENKDVAKRYEKYAEA
                     QAWMIDNSLIMSAMSSGGTASVTKVTPFTRGYSLVGIKGDGNNYKYMKLQKDTVTTKQ
                     FEEAKTKWEQESKKAIEKAQKEAEKHVK"
     gene            136672..137772
                     /gene="glf"
                     /locus_tag="VU722_000143"
     CDS             136672..137772
                     /gene="glf"
                     /locus_tag="VU722_000143"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU1771210.1"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWETKTPQEVKDKIAEQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGLDFFANRQ
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEVLNEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDERNNAIFAKYQEEAATNDK
                     VIFCGRLADYKYYDMHVVIERALEVVAEELGQ"
     gene            138009..139988
                     /locus_tag="VU722_000144"
     CDS             138009..139988
                     /locus_tag="VU722_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1771211.1"
                     /translation="MKTRKVLALAGVTLLAAGVLAACSGGSGAQGEKTFAFTYETHPD
                     NLNYLTTGKAATSEITSNVIDGLLENDKYGNLIPSMAEDWSVSKDGLTYTYKIRQDAK
                     WYTSEGEEYAPVKAQDFVTGLKYATDKKAEALYLVQDSIKGLDAYAKGEITDFAQVGI
                     KALDDQTVQYTLNKPETFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPY
                     LLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLY
                     PTSASFAELEKSMKDNIVYTQQDSTTYLVGTNIDRQSYKHTSKTSDEQKTSTKKALLN
                     KDFRQAIAFGFDRTAYASQLNGETGASKILRNLFVPPTFVQADGKNFGDIVKEKLVTY
                     GDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQR
                     VQSMKQSLEATLGTDNVVIDIQQLQKDELLNVTLFAENAAGEDWDLSDNVGWGPDFAD
                     PSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRYD
                     KYAAAQAWLTDSALIIPTTSKTGRPILSKMVPFTIPFALSGNKGTSDPVLYKYLELQD
                     KAVTADEYQKAQEKWMKEKAESNKKAQEELAKHVK"
     gene            complement(140153..142306)
                     /locus_tag="VU722_000145"
     CDS             complement(140153..142306)
                     /locus_tag="VU722_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU1771212.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     SIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSAMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKQYGASSEKMAAAYAAFANGGIYHKPMYINKVVFS
                     DGSEKEFSDVGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLAQAGKTGTSNYTDD
                     EIEKHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMITY
                     LSEDTHPEDWTMPDGLFRNGEFVFKNGARPIWTEPSTQQSSTAESSTTQASTTVGQQP
                     NNAPATDPNQGQAVQPTQPVQPTPQNPQVQQQPQQ"
     gene            complement(142303..142899)
                     /gene="recU"
                     /locus_tag="VU722_000146"
     CDS             complement(142303..142899)
                     /gene="recU"
                     /locus_tag="VU722_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU1771213.1"
                     /translation="MVNYPHKLSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            142966..143493
                     /locus_tag="VU722_000147"
     CDS             142966..143493
                     /locus_tag="VU722_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU1771214.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            143563..143904
                     /gene="gpsB"
                     /locus_tag="VU722_000148"
     CDS             143563..143904
                     /gene="gpsB"
                     /locus_tag="VU722_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU1771215.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            143925..144305
                     /gene="rnpB"
                     /locus_tag="VU722_000149"
     ncRNA           143925..144305
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VU722_000149"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            144390..145547
                     /locus_tag="VU722_000150"
     CDS             144390..145547
                     /locus_tag="VU722_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU1771216.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWVSDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAVGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            145560..146966
                     /gene="mapZ"
                     /locus_tag="VU722_000151"
     CDS             145560..146966
                     /gene="mapZ"
                     /locus_tag="VU722_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU1771217.1"
                     /translation="MSKKRRNRHKKENQESRFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHKDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILPPLPLDDEEQGLDSLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     VLTALALVSVIICVSAYYVYRQVNRSTKEIQTSQSATANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSETSSSSSS
                     QASSNTTSETSPSSSNAASNETRSSRSEVNMGVSSAGVAVQRSASRVAYNQSAIDDSN
                     NSAWDFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNC
                     KTGYFVGNGAGHADDLDY"
     gene            147042..148466
                     /gene="gndA"
                     /locus_tag="VU722_000152"
     CDS             147042..148466
                     /gene="gndA"
                     /locus_tag="VU722_000152"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU1771218.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILNRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPADFKFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            148478..149164
                     /locus_tag="VU722_000153"
     CDS             148478..149164
                     /locus_tag="VU722_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1771219.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSVALQ
                     TDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVLDHREELQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQ"
     gene            149265..150227
                     /gene="cbpC"
                     /locus_tag="VU722_000154"
     CDS             149265..150227
                     /gene="cbpC"
                     /locus_tag="VU722_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU1771220.1"
                     /translation="MKILKKMMQVLLAVFFFGLLATNTVFANTTGGRFIDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDGGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTINIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            150246..151244
                     /gene="cbpJ"
                     /locus_tag="VU722_000155"
     CDS             150246..151244
                     /gene="cbpJ"
                     /locus_tag="VU722_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU1771221.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(151362..152594)
                     /locus_tag="VU722_000156"
     CDS             complement(151362..152594)
                     /locus_tag="VU722_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter permease"
                     /protein_id="HEU1771222.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLRILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLASIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            154124..154453
                     /locus_tag="VU722_000157"
     CDS             154124..154453
                     /locus_tag="VU722_000157"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1771223.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
     gene            154575..155453
                     /gene="mvk"
                     /locus_tag="VU722_000158"
     CDS             154575..155453
                     /gene="mvk"
                     /locus_tag="VU722_000158"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU1771224.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLSHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            155435..156388
                     /gene="mvaD"
                     /locus_tag="VU722_000159"
     CDS             155435..156388
                     /gene="mvaD"
                     /locus_tag="VU722_000159"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU1771225.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            156375..157382
                     /locus_tag="VU722_000160"
     CDS             156375..157382
                     /locus_tag="VU722_000160"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU1771226.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDEQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            157366..158376
                     /locus_tag="VU722_000161"
     CDS             157366..158376
                     /locus_tag="VU722_000161"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU1771227.1"
                     /translation="MTTNRKDEHIRYALEQKSSYNSFDEVELIHSSLPLYDLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSDKGKEINQKLAQVAETCGILFVTGSYSVALKDSADDS
                     FSVKSSHPNLLLGTNIGLDKSVELGLQTVEEMTPLLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDVKTIERAYELGVRTFDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQDWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELIESYTVEEVIDIVQGWKDDLRLLMCALNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            158453..159151
                     /locus_tag="VU722_000162"
     CDS             158453..159151
                     /locus_tag="VU722_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU1771228.1"
                     /translation="MRKFKIFLFIEVCLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVVASILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCKFDDINLFRLMGRDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTAMIGDVEVVRG"
     gene            159148..160143
                     /locus_tag="VU722_000163"
     CDS             159148..160143
                     /locus_tag="VU722_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1771229.1"
                     /translation="MKKQAYVIIALTSFLFVLFFSHSLLDILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGVEELSLRKMQANLKRLLAGQEVVQLADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLSREEEIIEKERKRIARDLHDTVSQELFAAHMILSGVSQ
                     QSLKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLVEGIQVLLKELED
                     KSDLKVSFKQNVTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDLELQLKV
                     VDNGIGFQSGSFDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            160157..160789
                     /locus_tag="VU722_000164"
     CDS             160157..160789
                     /locus_tag="VU722_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1771230.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLTILKEWPEAKILIVSSYLDNEKIMPVLNAGAKGYML
                     KTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEDLTARERDVLQLIAKGY
                     ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGREDF"
     gene            161009..162343
                     /locus_tag="VU722_000165"
     CDS             161009..162343
                     /locus_tag="VU722_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU1771231.1"
                     /translation="MKKTFYKKLGISIIASTLLASQLSTVSALTVISSTGEEYEVSET
                     LQKSPGTNNLSLPEISPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVKATFK
                     IKNADSVEIGTGRGSASFIKDNVLITAAHVVYDRESKTEATEVEIMPAATPDSNPFGE
                     IKVKEVRYLKEFRNTAPNELTTYDLAVLILEEPIGAQLGTLGLPNNLENTKNLDVTVT
                     GYSAVNKGIKQMYTDTKTILQDTNDFLFYQIDTKGGASGSAVYDSNNRIVGVHTNGSD
                     PEQMNYAVKLNEKALSFIYSVIKGHSIDGWKLISDTWYYYKNSNKQTGWQKINDTWYY
                     LDASGKMLTDWQKVNGKWYYFGSSGSMATSWKYVGGRWYYFDKTNGDMKTGWYKDGST
                     WYYLDPTNGDMKKGWIKVGGNWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI"
     gene            162361..163380
                     /gene="cbpC"
                     /locus_tag="VU722_000166"
     CDS             162361..163380
                     /gene="cbpC"
                     /locus_tag="VU722_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU1771232.1"
                     /translation="MKILKKTMQVGLTVFFFGLLATSTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDKGEMVVGWQYIEIPGTGYRDNLLDNQPVNEIALQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYTPSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     QTGWQYLGNNWYYLRSSGAMATGWVKDGSTWYYLDAQNGDMKTGWAYVGNSWYYLRSS
                     GAMSTGWVKDGSTWYYLNASNGDMKTGWFQVNGKWYYAYSSGALAVNTTVGGYYVNYN
                     GEWIK"
     gene            163698..164981
                     /locus_tag="VU722_000167"
     CDS             163698..164981
                     /locus_tag="VU722_000167"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU1771233.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFNSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDDVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGDTVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLAELKEKYRKEL
                     AAAKEEAYKDAVEGAAIDKAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(165029..167395)
                     /locus_tag="VU722_000168"
     CDS             complement(165029..167395)
                     /locus_tag="VU722_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU1771234.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQINRYERAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGDNTIDEILQHPEKLEDIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLIHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSQDLETIQKHIATIEEELGIEYDS
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRSGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHFRKGDKVIHLVNDAEINVFNGDLGVI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLIEN
                     VEEKQQAVSETATSSTSEQSYTLTEENWDSIPAMIGITDADLKEIFGK"
     gene            complement(167675..168289)
                     /gene="lepB"
                     /locus_tag="VU722_000169"
     CDS             complement(167675..168289)
                     /gene="lepB"
                     /locus_tag="VU722_000169"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU1771235.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQSFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(168293..169174)
                     /locus_tag="VU722_000170"
     CDS             complement(168293..169174)
                     /locus_tag="VU722_000170"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU1771236.1"
                     /translation="MASITLTPSEKEIQSFLEHYQTSLAPSKNPYIRYFLRLPQATVS
                     IYTSGKVLLQGEGAEKYARFFGYQIVEENSDQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEIIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSIIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            169261..169563
                     /gene="zapA"
                     /locus_tag="VU722_000171"
     CDS             169261..169563
                     /gene="zapA"
                     /locus_tag="VU722_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU1771237.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            169560..170108
                     /locus_tag="VU722_000172"
     CDS             169560..170108
                     /locus_tag="VU722_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU1771238.1"
                     /translation="MISLLLLLVLAWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANPQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLLPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAAIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            170327..172663
                     /locus_tag="VU722_000173"
     CDS             170327..172663
                     /locus_tag="VU722_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU1771239.1"
                     /translation="MNKKILETLEFNKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRGVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGVFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLASEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDDRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKHVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      172827..172915
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            173006..174328
                     /locus_tag="VU722_000174"
     CDS             173006..174328
                     /locus_tag="VU722_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU1771240.1"
                     /translation="MLELLKSIDAFVWGPPLLILLLGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDQGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPATIALVFTSAFSPLAVVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            174546..175094
                     /locus_tag="VU722_000175"
     CDS             174546..175094
                     /locus_tag="VU722_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU1771241.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKANNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLT
                     ILCNYANNLANTPINPELQPYA"
     gene            175204..176103
                     /locus_tag="VU722_000176"
     CDS             175204..176103
                     /locus_tag="VU722_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU1771242.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIADFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(176128..177402)
                     /gene="serS"
                     /locus_tag="VU722_000177"
     CDS             complement(176128..177402)
                     /gene="serS"
                     /locus_tag="VU722_000177"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU1771243.1"
                     /translation="MLDIKRIRTDFETVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQTRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(177616..177987)
                     /locus_tag="VU722_000178"
     CDS             complement(177616..177987)
                     /locus_tag="VU722_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU1771244.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(177990..179354)
                     /locus_tag="VU722_000179"
     CDS             complement(177990..179354)
                     /locus_tag="VU722_000179"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU1771245.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIMVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSRIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
BASE COUNT        54265 a        32719 c        39924 g        52627 t
ORIGIN      
        1 gactaaactg atagtaacat gtagcgaaag gggtaggtac atgattaaaa tttatacagt
       61 ctcaagttgt actagctgta aaaaagcaaa aacctggctc aatgcccacc agttaagtta
      121 taaagaacaa aaccttggta aagaaggaat tacgagagaa gaattactgg atattctaac
      181 caaaacagat aacggaatag ccagcatcgt ttcgtctaaa aatcgctatg ccaaagccct
      241 tggagtggat attgaagatt tgagtgtcaa tgaagttctc aatctgatta tggaaacacc
      301 gagaatttta aagagcccaa tccttgtaga tgaaaaacgt ctgcaagttg gctacaagga
      361 agacgatatt cgtgccttcc taccacgctc tgtccgtaat gtagaaaatg cagaagcacg
      421 tttgcgtgca gctctataaa catcaaggct gggagcactt cccagtctta ttctatttta
      481 atttcaaaaa gaaagaagaa agaaatgaaa aaaatagttc ttgttagtct agctttcctt
      541 tttgtcctgg ttggttgcgg acagaaaaaa gaaactggat cagctacaaa aacagaaaaa
      601 gatacgcttc agtcggcatt gccagttatt gaaaatgctg agaagaatac agttgtaact
      661 aagactttgg tcttgcccaa gtcagatgat ggtagccagc agacacaaac aattacttac
      721 aaggacaaga cttttttgag tctaactatc caacaaaaac gtccagtctc tgatgagttg
      781 aagacttata ttgaccaaca tggagtggag gaaactcaaa aagctcttct tgaagcggag
      841 gagaaggata agtctatcat tgaagctcgt aaattggcag gtttcaaact tgaaacaaaa
      901 ctattgagcg caacggaact tcaaacaacg actagttttg attttcaagt tctggatgtc
      961 aagaaggctt cccagttgga acatctgaag aatattggtt tggaaaatct tttgaaaaat
     1021 gaaccaagca actatatttc agatagattg gcaaatggcg cgacagaaca atagaaaatc
     1081 caaataaata gactgcctga attgtagaag gtaaggaatt atgctataat ggtactattc
     1141 taaggaaaga gggtgttaga atgggattta ctgaagaaac agtacgtttt aaattggacg
     1201 attccaataa aaaagaaatt agcgaaactt tgacagatgt ttatgcttcg ttgaacgata
     1261 agggttacaa cccaattaac caaatcgtag gttacgtatt gagtggagac cctgcctacg
     1321 ttcctcgtta taataatgca cgaaatcaaa tccgtaagta tgagcgtgat gaaatcgttg
     1381 aggaattggt tcgttactac ctcaaaggac aaggagtcga tctataacct atgagaatta
     1441 tgggattgga cgtcggttca aaaacggtag gggtggcgat tagcgatccg cttggtttta
     1501 cagctcaagg gcttgaaatc atccagataa atgaagaaca aggccaattt ggttttgacc
     1561 gcgttaagga attggttgat acttacaagg tggaacgatt tgtagtgggc ttgcctaaaa
     1621 acatgaacaa tacaagtgga ccgcgcgtag aagctagtca agcctacgga gcaaagctag
     1681 aagagttttt tggtttacca gtagactatc aggatgaacg cttgacaaca gtggctgctg
     1741 agcgcatgtt gattgaacaa gcagatatca gtcgcaataa gcgcaagaaa gtcattgata
     1801 agttagcagc tcagctgatt ttacaaaatt atttagatag aaaattttaa tataaaggag
     1861 aggctatgtc acacgatcat aaccacgacc acgaagaacg tgaactaatc acactagtag
     1921 atgagcaagg aaatgaaacc ttgtttgaaa tccttttgac aattgatgga aaagaagaat
     1981 ttggtaaaaa ctatgttctt ctagtaccag ttaacgcaga agaagacgaa gacggacaag
     2041 ttgaaatcca agcttactca ttcatcgaaa acgaagatgg aacagaaggc gaattgcaac
     2101 caatcccaga agactcagaa gacgaatgga acatgattga agaagtcttc aacagcttta
     2161 tggaggagta aaaacgtccg ggggacgttt ttagccctgc gctagaaatt agaaacgcag
     2221 gtagtctggg agactgtatc agcccaactc ccagaaatgg ggaagagttg gaacgtccag
     2281 tgaacatttt taccccaact cttagaaatt gagaagagtt ggaacatcta gtggatgttt
     2341 ttagcccata ttcacattca tagtagctag ttattagcta accaggtaag aggtcgggac
     2401 gaaaatcctg gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt
     2461 ttgtcaagga gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttga
     2521 attttcgatc aggtttgggc cgaatgcagc aagcggtgga tttgttagga aatcctgagc
     2581 agtcttaccc tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta
     2641 tgagggaatt atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg
     2701 tctctatcaa tgaccgaatc tgcattaatg ggcaacctat agcagacgca gactttatcc
     2761 gtttggctga tcaggtcaag gagatggaga aaacgcttct gcaaactcct gaccagttgt
     2821 ccttttttga attgctgacc ttagttgctt ttctttattt tagggagcaa gaggtggatt
     2881 tggttttatt agaagtggga attggtggct tacttgacac gaccaatgtg gtaactggag
     2941 agcttgctgt catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag
     3001 aagcaattgc agagcagaaa gctggtattt tcaaggctgg taagaaggca gtgattgcga
     3061 aattgcctcc agaagctagg cttgtctgtc agaaaaaagc cgaatcttta gctgttaacc
     3121 tttatcaggc aggtcaagat tttttaatgc tgaatggtga tttttcaagc tctttactaa
     3181 atctttcaca gctgaacata ggcttagaag gagtctatca gcaggagaat gcagccttgg
     3241 cgttgcaaac ttttcttctt tttatgggag aaggaaagga agctgttgat gaacaggctg
     3301 taagaaaggc cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga
     3361 tttatttgga tggtgctcat aacctccctg ccttgactcg cttggttgag tttatcaaag
     3421 aaaaagagca ggaaggttat cgacctcaaa tcctctttgg atccttgaaa cgtaaggatt
     3481 atcaagggat gttgggttat ctgactgaaa atttacctca agtggaactc aagatgactg
     3541 gctttgacta tcaagggtct ttggacgaga cagatgtaac aggttaccat gtaattccct
     3601 cttaccgaga atttatcagc agtttcgaag aaagggcaga cgctcaagac ttgctgttcg
     3661 taacagggtc tctctatttt atctcagaag tacggggcta cctgctggac cgtgagcaga
     3721 taaattgacc cccttttttg aacttgttat actaggggaa ttgctggtta gagaaaattt
     3781 ctctaaattg gtagcagaaa ggaaatccat catgaaatta aaaagattca cactttctct
     3841 tgcttctcta gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca
     3901 acagcctgtt gctcagcagc aggtccaaca gcctgctcaa cagaatacca atactgcaaa
     3961 tgcagggggt aaccaaaatc aagcggctcc agtacaaaac caacctgttg ctcagccgac
     4021 cgatattgat gggacttata ctggtcagga tgacggagac cgtatcactt tagtggtaac
     4081 tggaacgact ggtacatgga ctgagctcga atctgacggg gatcagaaag tcaaacaggt
     4141 tacatttgat tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa tttacactgt
     4201 aaacggtaat caaatcgtcg tagatgatat ggatagagac ccatcggacc aaatcgtttt
     4261 aactaaataa gactatgcaa gtagaaaggg ctggattttt cagccttttt acttttacct
     4321 agaaaataat cataaatact tgccttctac cgaatacctg cgttatacta gtatcaatta
     4381 cttgttttta gcattcaaac tatcaaggag gggatatgaa atataggaaa tttcaattat
     4441 tgatgtccaa gtatggcttt agtctttcga ttatgctact tgaactttgt ctggtttttg
     4501 gtctctttct ttatttagga cgcatggctc ccattttatg gattactgtc ctcattctac
     4561 tgagtatcat tacaatcatt tcgatagtca accgtaatac gactcctgag aataaggtaa
     4621 cctggttgtt agtagccttt gtgccagtat ttggcccctt gctctatctg atgtttggtg
     4681 aaaggcgatt gtcaaaaaaa gaaatcaaac aactgaagaa gctaggctcc atgcatttcc
     4741 aagaagcaaa tagccagcta ctaaaagaga aattaaaaga aagtgacaag gcagcttatg
     4801 gagtcatcaa gtccttattg agtatggata ccaatgctga catctatgat caaactgcct
     4861 ctacattttt tcctaacgga gaagctatgt ggaaaaagat ggtagaagat cttaaaaagg
     4921 ctgagaaatt tattttcttg gaatattaca ttatagaaga aggtttgatg tggaatcgca
     4981 tactagatat actagagcaa aaggtagctc agggtgtaga ggttaagatg ctctatgatg
     5041 atatcggctg tatggctact ttaacaggag attatgcaca tcgacttcgt cagctgggca
     5101 tcgaggccca taaattcaat aaagttattc ctcgtttgac agtggcttat aataacagag
     5161 atcatagaaa aatattgatt gttgatggtc agatagccta tactggtggg gtcaatctgg
     5221 cagatgagta cattaaccac gtcgagagat ttggttattg gaaggatagt ggaattcgct
     5281 tagacggact agcagtaaaa gccctgacac gcttattttt gaccacttgg tacattaatc
     5341 gaggagaaat tagtgatttt gatcaatatc atttagaaaa tcattctatc ccgagtgacg
     5401 gtttaaccat tccatacgga agtggaccca agccaatttt tcgagcgcag gtagggaaaa
     5461 aagtttatca gagtttaatc aatcaagcaa cggaatcggt ctatattacg acaccttatt
     5521 tgattataga ttatgattta acagagacaa tcaaaaatgc agctatgaga ggggtcgatg
     5581 ttcgaattat caccccttac ataccagata agaagttcat tcagttagtc acgagaggag
     5641 cttatcccga ccttctttct gctggtgttc ggatttatga gtatagtcca ggttttattc
     5701 atagtaagca gatgttggta gacgaagatt ttgcggtggt ggggacaatc aatctcgact
     5761 accggagctt ggtacaccat tatgaaaatg cagtcttact ctataaaact ccttctataa
     5821 gggaaatcgc ccgagatttt cgaaatatat ttgcagattc tcaggaagtc tatcctcatt
     5881 ctatcaaaac gagctggtat caaaagcttg taaaagaaat cgcccagcta ttcgccccta
     5941 tcttataaga aatctagaac ttaggataca aaccagacct atttttcttg tcttttacga
     6001 atagaaagaa agaggagggg aattcatgct aactaaggaa gaagtgaatg atatgattga
     6061 gttcaaacag acacatttac accgctttcg ggaaattgaa acctttgtga aactatgcaa
     6121 aaaatcactc aaacagccat cgcaagctga caatcctagg actttttgat atactaagac
     6181 agataaattg aacaggagaa acgatatgag tgtgtatggt agagtagaag aagttcataa
     6241 ggagaatcgt gaacctctag aataccaaat cgaacaagaa tcgcatcatc gtgaatcaag
     6301 tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt gtaacgggga taactctagg
     6361 agtaccgcta ttactcgact taatgagtgc acaagaagtg caggattttt atgcaggttg
     6421 ggcgcttcat cagacaggga agatttacag cgactattat ggaagtcaag gtttgcttta
     6481 ttatttgctg acttacgtga gtcagggcgg atttttcttt gccatctttg agtggttagc
     6541 cttggtagca ggaggatttt tcctttttag atcagcggac accttgacag agcaaggaga
     6601 ccaagctgga catctggtga ctatttttta catgctagtt acaggtcttg cttttggtgg
     6661 aggctatgcg actcttttag cgcttccttt cttattcgca gcctttagtt tagttgcggc
     6721 ttacctaagc aatccaagcc atgataaggg atttgtacgg attgggctag ctttggcagg
     6781 cggatttttc tttgctccct tatcatcgtt cctgtttatt gctgtagtga gtttaggctt
     6841 gttggtcttt aaccttgggc atagacgctt tgcgcatggg ttttatcagt ttcttgcagt
     6901 ggctttaggt ttttcacttg tcttttatcc aactgcctac tatagtgctg caacaggaag
     6961 ttttggggat gcgattagtg gtattcgtta tcctattgac agtattcgct ttgattttac
     7021 ttctaaaatt ttagagaata tgttttttta tggcttgttg tcccttggtt tgggatttgt
     7081 ggtttgtatc tttttaggtc tctttcaatc caaacccttt aaactatacg tcatttcggt
     7141 tcctgcaagt cttgtggtaa ttttaggttt gattttactt ttcttttcac aagagcctct
     7201 gcacgcttct tatttgatgg tcgtcttccc tgttttccta cttttattgg taaccaatat
     7261 taagagtcaa cagagggggc gtagtgctag aagaagccga agagaaacgc cagttagcct
     7321 atggagtcgt ttcttcaaag gaaatctata tctgctagtt tttgggtttg tctatctttt
     7381 gtctgttcct tttttgatga agtttgtcct ttatccagta ccttatcaag aacgtaatcg
     7441 tcttgctgat ttggtaaaag aggagacaaa tacggaagat gctatctatg catgggatga
     7501 tactgcgact ctttatcgta agagtgagcg cttgtcgcca tcggcgattt tgtccccgtt
     7561 gcactataca gcaactgagg aaaatcgtaa taagttactt aatgacttga aagaaaaaca
     7621 acctaaggtg attgtggtaa atgataaggt ggtagtctgg tctgaagtgg aaacactctt
     7681 aaaagaaaat taccaacaag taaagactga ttactcagag tttaaagtct ataaaattaa
     7741 ataaccaaat caatatcttg tgtattttta aaaattttag gatttttaac acaagatatt
     7801 gatttttctt tttagagtgg tataatactt tttagaaaga acattttaga aaagagcatg
     7861 catatgattg cactagaaga aaaaattaca attttgccaa ctctcttcgt cgagaaacga
     7921 gatgggagac gtgttgtatt tgatgtggac aagattgaca aggctctcca caaggcggct
     7981 gacaaggtta tggatgtgac acccctggtt gaaaaacgcc tcgatgatct gactgagcga
     8041 attattacag aaattcatag tcgctttcca cagggaatta agatttacga aattcaaaat
     8101 atcgtagaac atgaactcct tgaagccaaa gaatatgcgc tggctgagga gtatattact
     8161 tatcggacac agagggattt tgagcgctca aaagcgacgg atatcaactt tagtattcat
     8221 aaacttctca acaaagacca gacagttgtc aatgaaaacg ctaataaaga cagtgatgtc
     8281 tttaacactc agcgtgattt gacagcaggg attgttggga aatcaatcgg actgcaaatg
     8341 cttcctaagc acgtagccaa tgcccaccaa aagggggata tccactatca cgatttggac
     8401 tacagtccct atacccctat gaccaactgc tgtttgattg attttaaggg tatgttggaa
     8461 aatggtttta agattggaaa tgcagaggta gagagtccca agtctatcca gactgcgaca
     8521 gcacagattt ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg ctgttcagct
     8581 gaccgtatcg atgaaatttt ggcgccttat gcagagaaga attatcaaaa acatctcaaa
     8641 gatgcagaag agtgggtatt gcctgaaaaa caggaagatt acgcttggaa gaaagcgcaa
     8701 aaggacatct acgatgccat gcaatctctt gagtatgaaa tcaatactct cttcacttca
     8761 aatggacaaa caccttttac ttcgttaggt tttggtctgg gaaccagtcg ttttgaacga
     8821 gaaattcaaa aagctatttt aaacattcgc atcaagggtc ttggttcaga acaccgtacg
     8881 gctatctttc ctaaacttat ctttacgctt aaaagaggcc tcaacttaga ggaaggaact
     8941 cccaactatg acatcaagca gttggctcta gagtgtgcaa ccaagcggat gtatccagac
     9001 gtcttgtctt atgataagat tgttgatttg acaggttctt tcaaggtgcc tatgggctgc
     9061 cgttctttcc ttcaagggtg gaaggatgaa aatggtgtag aagtcaattc aggtcgcatg
     9121 aatctgggtg ttgtgacggt taatctgcct cgtattgctc ttgagtctga aggtgatatg
     9181 aataagttct gggaaatctt caacgagcga atgaatatcg cagaagatgc tcttgtttac
     9241 cgtgtcgaac gcactaaaga ggcgacacca gcgaatgctc ctattcttta tcagtacggt
     9301 gcttttggcc atcgtctagg taaagaagaa agtgttgacc agctctttaa gaatcgtcgt
     9361 gcgaccgttt cgctgggcta tatcggcttg tatgaagtag cgacagtttt ctttggtaac
     9421 agctgggaaa gtaatccaga tgctaaggaa ttcacgctag acatcattca cgatatgaaa
     9481 cgccgtgtag aagagtggtc agaccaatat ggctaccatt tctctatcta ctcaacacca
     9541 tccgaaagtc tgacagaccg tttctgccga ctagatatag acaagtttgg ctctattcct
     9601 gatatcacag acaaggaata ctacaccaat tctttccact acgatgttcg taaaaatcca
     9661 acaccgtttg aaaaattaga ctttgagaaa gtctatccgg aagcaggtgc gtcaggtggt
     9721 ttcatccatt attgtgagta tccagtcctt cagcaaaatc caaaggcctt ggaagctgtc
     9781 tgggattatg cttatgaccg tgtaggctat ctaggcacca atactccgat tgaccgttgc
     9841 tacaagtgtg actttgaagg ggattttgaa ccaactgaga gagggtttgc ttgtccaaac
     9901 tgtggcaata gcgatcctaa aacagtagac gttgttaaac ggacttgtgg ctatcttggc
     9961 aatcctcaag cgagaccaat ggttaacggg cgtcacaagg aaatcgctgc gcgtgtcaaa
    10021 catatgaatg gttcaacgat taaaatagct gggcatcaag taacaaatta gaaagaaatg
    10081 aaatgggaaa atatcaacta gacgataagg ggcgcgcaca agtgacccgt tatcacgaga
    10141 agcactctaa aggtggagct ggtaagaaag aacgcttgct tagcttcaga gaacaatttt
    10201 taaacaagaa caagaaaaaa taaaagtgag agccagctct cgcttttctc atagtgggag
    10261 gtagggatgg aattacgcag accaagatta gcggataaga aagctgtttt agatatgatg
    10321 acagagtttg aaaagagcca atcagcccat gatggaggat tttgggatgt tgaggatttt
    10381 tcttacgagg agtggctaga aggtaaccgt aataaagaaa tgggaatatg gctacctgaa
    10441 aatcgcgttc catcgataca gttcgtattg tttggtgaat caggttgtgc tctaggattt
    10501 ttgaatctgc gattgagact gaatgagggg ttactgaatt atgctggcca cattggctac
    10561 tccattcgtc catctgaaag aggcaagggt tatgcaaaag agactctccg tcagggcttg
    10621 caagttgcta aggaaaagaa catcaagaaa gctctggtga cctgtagtgt gaataatcct
    10681 gctagcagag cagtcattct agcaaatggt ggaatatttg aggatgctcg caatggagtc
    10741 gagcgttatt ggatagaggt agcgaatgaa taatccaaaa ccacaagaat ggaaaagcga
    10801 ggaacttagt caaggtcgta tcattgacta caaggccttt aactttgtgg acggcgaagg
    10861 cgtgcgcaac tctctctatg tatcaggctg tatgtttcac tgcgagggat gttataatgt
    10921 tgcgacttgg tcttttaatg ctggcattcc ctatacagca gaattagaag agcagattat
    10981 ggcagacctt gcccaaccct atgttcaagg cttgactttg ctgggagggg agccttttct
    11041 caatactggc attctcttgc ctctagttaa acgcatccga aaggaattgc cagacaagga
    11101 catttggtcc tggacgggct acacttggga agaaatgatg ttggaaactc cagataaact
    11161 ggaactctta tcattgattg acattcttgt cgatggacga tacgatcgaa ctaagagaaa
    11221 tctcatgctc cagtttcgag gttcgtccaa ccaacgaatt atcgatgtgc aaaaatcgct
    11281 caaaagtggg caagtagtga tttgggacaa gctcaatgac ggaaaagaaa gctatgaaca
    11341 ggtgaagaga gaatgaagaa aaaggactta gtagaccaac tagtctcaga gatcgagacg
    11401 gggaaagtca ggacactggg aatatacggt catggagctt caggtaaatc aacctttgca
    11461 caggaattgt accaagcttt agattctact acagtaaatt tgctagagac agatccttat
    11521 atcacctcag gacgccatct ggtagtaccc aaggacgcgc cgaatcaaaa ggtgacagcc
    11581 agtctgccag tggcgcatga actggagagt ttgcagagag atatccttgc cttgcaggcg
    11641 ggtatggatg tcttgacaat tgaagaacct tggaaggcta gtgaggtctt gtctggagcc
    11701 aaaccaattt tgattgtcga agggatgtct gttggctttc tacccaagga actctttgaa
    11761 aaaaccatct gtttctacac ggatgaggag accgaattaa agcgacgcct tgctagagat
    11821 acgactgtga gaaatcgcga tgcatccttt atattggcta gccatcagat gagacgggag
    11881 cagtatctgc gatactataa agaaactgag tctaaggcgg atatcttagt ggaccaatca
    11941 gaagataaat ttgatgtcaa gaggacttaa cttatgtata gaagaaatat agaagaaaat
    12001 ccctaatttt agaaagaaaa agtaggaaaa cagtttcatc ccaaaaaaac gaaaaaacag
    12061 caacaaatcc cttgcaatcg caggggcttt gtgttattct attatggtgc tgtaaattac
    12121 agccttagtt ttgatgcaag aggttgcgac acgctcggtt gcattgccac gcaacaccgc
    12181 gtcggttttc ttgtggagct agcctattat cttaaataga cgaaaaggag aaaaagatgg
    12241 caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt gacacagcgg
    12301 ctgcaaaaat cgtagaatca gctactcgta caggtgcaca agttgcgggt ccaatcccac
    12361 ttccaactga acgtagcctc tacacaatca ttcgtgcgac tcacaaatac aaagactctc
    12421 gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga tatcgttaac ccaactcaaa
    12481 aaacagttga tgccttgatg aaattggatc ttccaagtgg tgtaaacgta gaaatcaaac
    12541 tttaatctaa aatataaaag agcagaggct ggtgtttcaa tctaattgaa cacggactaa
    12601 actcggtgtg aaaaagataa acttcctagt gtctgctaga cactgcgtca gtttcctatt
    12661 ttcacgttga gtttgacgcc ctttgtatct tagacttgag cataaaaaac gctcgttaaa
    12721 aactttttga ataaaaaata tagaaaagga actattttct catgacaaaa ggaatcttag
    12781 ggaaaaaagt gggaatgact caaatcttca ctgaagctgg cgaattgatc cctgtaacag
    12841 ttattgaagc aactccaaac gttgttcttc aagttaaaac tgttgaaaca gacggataca
    12901 acgctatcca agttggtttc gatgacaaac gcgaagtatt gagcaacaaa cctgctaaag
    12961 gacatgtagc gaaagctaac acggctccta agcgcttcat tcgtgaattc aaaaacgttg
    13021 aaggcttgga agttggcgct gaaatcacag ttgaaacatt cgcagctgga gatgttgttg
    13081 acgtaacggg tacttctaaa ggtaaaggtt tccaaggtgt tatcaaacgc cacggacaat
    13141 cacgtggacc aatggctcac ggttctcgtt accaccgtcg tccaggttct atgggacctg
    13201 ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg gcgtatgggt ggcgaccgcg
    13261 taacaattca aaaccttgaa gttgtacaag ttgttccaga aaagaacgtt atccttatca
    13321 aaggtaacgt accaggtgct aagaaatctc ttatcactat caaatcagca gttaaagctg
    13381 gtaaataata aagaaagggg aaatcagtca caatggcaaa cgtaacatta tttgaccaaa
    13441 ctggtaaaga agctggccaa gttgttctta gcgatgcagt atttggtatc gaaccaaatg
    13501 aatcagttgt gtttgatgta atcatcagcc aacgcgcaag ccttcgtcaa ggaacacacg
    13561 ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa accatggcgt caaaaaggaa
    13621 ctggacgtgc tcgtcaaggt tctatccgct caccacaatg gcgtggtggt ggtgttgtct
    13681 tcggaccaac tccacgttca tacggctaca aacttccaca aaaagttcgt cgcctagctc
    13741 ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt cgtagctgta gacgctcttt
    13801 catttacagc tccaaaaact gctgaatttg caaaagttct tgcagcattg agcatcgatt
    13861 ctaaagttct tgttatcctt gaagaaggaa atgaattcgc agctctttca gctcgtaacc
    13921 ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt tcttgacatc gcaaatagcg
    13981 acaaacttct tgtcacacaa gcagctatct ctaaaatcga ggaggttctt gcataatgaa
    14041 tttgtatgat gttatcaaaa aacctgtcat cactgaaagc tcaatggctc aacttgaagc
    14101 agggaaatat gtatttgaag ttgacactcg tgcacacaaa cttttgatca agcaagctgt
    14161 tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac acaatcaacg taaaaccaaa
    14221 agctaaacgt gttggacgtt acactggttt tactaacaaa actaaaaaag ctatcatcac
    14281 acttacagct gattctaaag caatcgagtt gtttgctgct gaagctgaat aatctaagga
    14341 ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa acggtcgccg taatatgact
    14401 tctttggatt tcgctgaaat cacaacaagc actcctgaaa aatcattgct tgttgcattg
    14461 aagagcaagg ctggtcgtaa caacaacggt cgtatcacag ttcgtcacca aggtggtgga
    14521 cacaaacgtt tctaccgttt ggttgacttc aaacgtaata aagacaacgt tgaagcagtt
    14581 gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca tcgctcttgt acactacact
    14641 gacggtgtga aagcatacat catcgctcca aaaggtcttg aagtaggtca acgtatcgtt
    14701 tcaggtccag aagcagatat caaagtcgga aacgctcttc cacttgctaa catcccagtt
    14761 ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg gtggtgaatt ggtacgtgct
    14821 gctggtgcat ctgctcaagt attgggttct gaaggtaaat atgttcttgt tcggcttcaa
    14881 tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta cagttggtgt tgtcggaaac
    14941 gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta gctgttggaa aggtatccgc
    15001 ccaacagttc gtggttctgt aatgaaccct aacgatcacc cacacggtgg tggtgaaggt
    15061 aaagcaccag ttggtcgtaa agcaccatct actccatggg gcaaacctgc tcttggtctt
    15121 aaaactcgta acaagaaagc gaaatctgac aaacttatcg ttcgtcgtcg caacgagaaa
    15181 taatattaga ctagtcgctt aagcaactag taaatccgcc agctcggtag cgctccatag
    15241 gagtgcaagc cgctgtggta caacatttaa aggagaaaat ataaaaatgg gacgcagtct
    15301 taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa gttgaagctc aagctaacga
    15361 cgaaaagaaa aaagttatta aaacttggtc acgtcgttca acgatcttcc caagtttcat
    15421 tggttacact attgcagttt atgacggacg taaacacgta cctgtttaca tccaagaaga
    15481 catggtaggc cacaaacttg gtgaatttgc accaactcgt acttacaaag gtcacgctgc
    15541 agacgacaag aaaacacgta gaaaataagg agaacataaa tggcagaaat tacttcagct
    15601 aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat cacgtcttgt tcttgataac
    15661 atccgtggta aaagcgtagc cgatgcaatc gcaatcttga cattcactcc aaacaaagct
    15721 gctgaaatca tcttgaaagt tttgaactca gctgtagcta acgctgaaaa caactttggt
    15781 ttggataaag ctaacttggt agtatctgaa gcattcgcaa acgaaggacc aactatgaaa
    15841 cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca acaaacgtac agctcacatc
    15901 actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt acatccaatt
    15961 ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat ggtatgctga aaaagaatac
    16021 gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg ttcaaaaaga acttgctgac
    16081 gcagcagttt caactattga aatcgaacgc gcagtaaaca aagttaacgt ttcacttcac
    16141 actgctaaac caggtatggt tatcggtaaa ggtggtgcta acgttgatgc actccgtgca
    16201 aaacttaaca aattgactgg aaaacaagta cacatcaaca tcatcgaaat caaacaacct
    16261 gatttggatg ctcaccttgt aggtgaagga attgctcgtc aattggagca acgtgttgct
    16321 ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc gtgctggagc taaaggaatc
    16381 aaaactcaag tatcaggtcg tttgaacggt gcagatatcg cccgtgctga aggatactct
    16441 gaaggaactg ttccgcttca cacacttcgt gcagatatcg attacgcttg ggaagaagca
    16501 gatactacat acggtaaact tggtgttaaa gtatggatct accgtggtga agttcttcca
    16561 gctcgtaaaa acactaaagg aggtaaataa ccaatgttag tacctaaacg tgttaaacac
    16621 cgtcgtgaat tccgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga agtagcattc
    16681 ggtgaatacg gtcttcaagc tacaactagc cactggatca ctaaccgcca aatcgaagct
    16741 gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta aagtttggat taaaatcttc
    16801 ccacacaaat catacactgc taaagctatc ggtgtgcgta tgggatctgg taaaggggca
    16861 cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga tgttcgaaat cgctggtgta
    16921 tctgaagaga ttgcacgtga agcgcttcga cttgctagcc acaaattgcc agttaaatgt
    16981 aaattcgtaa aacgtgaagc agaataagga gaaggcatga aacttaatga agtaaaagaa
    17041 tttgttaaag aacttcgtgg tctttctcaa gaagaactcg cgaagcgcga aaacgaattg
    17101 aaaaaagaat tgtttgaact tcgtttccaa gctgctactg gtcaattgga acaaacagtt
    17161 cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa cagttcaatc tgaagcgaaa
    17221 taatagacta gggaaggaga aatttcaatg gaacgcaata atcgtaaagt tcttgttgga
    17281 cgtgttgtat ctgacaaaat ggacaagaca atcacagttg tagttgaaac aaaacgtaac
    17341 cacccagtct atggtaaacg tattaactac tctaaaaaat acaaagctca tgatgaaaac
    17401 aatgttgcca aagaaggcga tatcgtacgt atcatggaaa ctcgcccgct ttcagctaca
    17461 aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca tcatctaatc aaacctgaaa
    17521 ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa gtcgcagaca acagcggtgc
    17581 tcgcgaaatc ttgactatca aagttcttgg tggttcagga cgtaaatttg caaacatcgg
    17641 tgatgttatc gtggcatctg taaaacaagc tactcctggt ggtgcggtta aaaaaggtga
    17701 cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct cgtcgtgctg atggttcata
    17761 catcaaattt gacgaaaacg cagcagttat catccgtgaa gacaaaactc ctcgcggaac
    17821 acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt ggcttcatga agatcgtgtc
    17881 acttgctcca gaagtacttt aatttttagg aacaaactag tcccctagct tcaagctagg
    17941 gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa tgtttgtaaa aaaaggcgac
    18001 aaagttcgcg taatcgctgg taaagataag ggaacagaag ctgttgtcct tactgccctt
    18061 ccaaaagtaa acaaagttat cgttgaaggt gttaacattg ttaagaaaca ccaacgtcca
    18121 actaacgagc ttcctcaagg tggtatcatc gagaaagaag cagctatcca cgtatcaaac
    18181 gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg gttacaaatt tgtagacggt
    18241 aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga
    18301 gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa tgaagtagtt cctgctttga
    18361 cagaacaatt caactactca tcagtgatgg ctgtgcctaa agtagataag attgttttga
    18421 acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct tgaaaaagct gctgaagaat
    18481 tggcacttat ctcaggtcaa aaaccactta tcactaaagc taaaaaatca atcgccggct
    18541 tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac ccttcgtggt gaacgtatgt
    18601 acgaattctt ggataaattg gtatcagttt cacttccacg tgtacgtgac ttccacggtg
    18661 ttccaacaaa atcatttgat ggacgcggga actacacact tggtgtgaaa gaacaattaa
    18721 tcttcccaga aatcaacttc gatgacgttg acaaaactcg tggtcttgac atcgttatcg
    18781 taacaactgc taacactgac gaagagtcac gtgcattgct tacaggcctt ggaatgcctt
    18841 ttgcaaaata atataggagg taaatctaat ggctaaaaaa tcaatggtag ctagagaggc
    18901 taaacgccaa aaaattgttg accgttatgc tgaaaaacgt gctgcattaa aggcggcagg
    18961 ggactacgaa ggtttatcta aattacctcg caacgcctca ccgactcgtt tacataatcg
    19021 ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa tttggtctga gtcgtatcgc
    19081 ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta acaaaagcat cttggtaata
    19141 tcatgataca aagagcgtaa caaccacagc gaaaatagga aatttggtga gggagcgatg
    19201 ctccaaaaca aatttatctt ttttgcacag gttgtagctc gtgttcaaat aagagttctc
    19261 tcatttgaat gtgtcaatac tatctgagcc cagctcaatc attaactagc aagtgcaact
    19321 tgcaaactac tagtaagagg agaaaaacaa aatggttatg actgacccaa tcgcagactt
    19381 cctaactcgt attcgtaatg ctaaccaagc taaacacgaa gtacttgaag tacctgcatc
    19441 aaacatcaaa aaagggattg ctgaaatcct taaacgcgaa ggttttgtaa aaaacgttga
    19501 aatcattgaa gatgacaaac aaggcgtcat ccgtgtattt cttaaatacg gaccaaatgg
    19561 tgagaaagtt atcactaact tgaaacgtgt ttctaaacca ggacttcgtg tctacaaaaa
    19621 acgtgaagac cttccaaaag ttcttaacgg acttggaatt gccatccttt caacttctga
    19681 aggtttgctt actgataaag aagcacgcca aaagaatgtt ggtggtgagg ttattgctta
    19741 cgtttggtaa aatcaagata caaagctcgt aaagaacaaa gcaaaattag gaagttggag
    19801 aagtttgttt acaaacaagc caacttatct attttgcaca gttcttagag cgtgttcagt
    19861 tcagctcttg aactaaataa gtatctgaac cccgtgaaaa ctggccgttc tggcctgaca
    19921 atttaacagg agaaaataaa catgtcacgt attggtaata aagttatcgt gttgcctgct
    19981 ggtgttgaac tcgctaacaa tgacaacgtt gtaactgtaa aaggacctaa aggagaactt
    20041 actcgtgagt tctcaaaaga tattgaaatc cgtgtggatg gtactgaagt aactcttcac
    20101 cgtccaaacg attcaaaaga aatgaaaact atccacggaa ctactcgtgc ccttttgaac
    20161 aacatggttg ttggtgtatc agaaggattc aagaaagaac ttgaaatgcg tggggttggt
    20221 taccgtgcac agcttcaagg atctaaactt gttttggctg ttggtaaatc tcatccagac
    20281 gaagttgaag ctccagaagg aattactttt gaacttccaa acccaacaac aatcgttgtt
    20341 agcggaattt caaaagaagt agttggtcaa acagctgctt acgtacgtag ccttcgttca
    20401 ccagaaccat ataaaggtaa aggtatccgt tacgttggtg aattcgttcg ccgtaaagaa
    20461 ggtaaaacag gtaaataatg ttgagtggtt gatcatcaac caccaaccta ttttccaact
    20521 ttgtgcatag cacacgattt aaaactaaag aggtgaaaac tgtgatttca aaaccagata
    20581 aaaacaaact ccgccaaaaa cgccaccgtc gcgttcgcgg aaaactctct ggaactgctg
    20641 atcgcccacg tttgaacgta ttccgttcta atacaggcat ctacgctcaa gtgattgatg
    20701 acgtagcggg tgtaacgctc gcaagtgctt caactcttga taaagaagtt tcaaaaggaa
    20761 ctaaaactga acaagccgtt gctgtcggta aactcgttgc agaacgtgca aacgctaaag
    20821 gtatttcaga agtggtgttc gaccgcggtg gatatctata tcacggacgt gtgaaagctt
    20881 tggctgatgc agctcgtgaa aacggattga aattctaata ggaggacact agaaaatggc
    20941 atttaaagac aatgcagttg aattagaaga acgcgtagtt gctgtcaacc gtgttacaaa
    21001 agttgttaaa ggtggacgtc gtcttcgttt cgcagctctt gttgttgttg gtgaccacaa
    21061 tggtcgcgta ggatttggta ctggtaaagc tcaagaagtt ccagaagcaa tccgtaaagc
    21121 agtagatgat gctaagaaaa acttgatcga agttcctatg gttggaacaa caatcccaca
    21181 cgaagttctt tcagaattcg gtggagctaa agtattgttg aaacctgctg tagaaggttc
    21241 tggagttgcc gctggtggtg cagttcgtgc cgttgtggaa ttggcaggtg tggcagatat
    21301 tacatctaaa tcacttggtt ctaacactcc aatcaacatt gttcgtgcaa ctgttgaagg
    21361 tttgaaacaa ttgaaacgcg ctgaagaaat tgctgccctt cgtggtattt cagtttctga
    21421 tttggcataa gaaaggggat aaaatggctc aaattaaaat tactttgact aagtctccaa
    21481 tcggacgcat tccatcacaa cgtaaaactg ttgtagcact tggacttggc aaattgaaca
    21541 gctctgttat taaagaagat aacgctgcta tccgtggtat gatcacagca gtatctcact
    21601 tagtaacagt tgaagaagta aactaatgaa gttttagggg atgtgcactg taccatcccc
    21661 taaaactaga tatagtcatc tatgatgaca tcgtataggc gagttgatgg gggagacaac
    21721 cttttctccc ttatcggcgc tagcatttta caaaagagga gaaaataaaa atgaaacttc
    21781 atgaattgaa acctgcagaa ggttctcgta aagtacgtaa ccgcgttggt cgtggtactt
    21841 catcaggtaa cggtaaaaca tctggtcgtg gtcaaaaagg tcaaaaagct cgtagcggtg
    21901 gcggagttcg ccttggtttt gaaggtggac aaactccatt gttccgtcgt cttccaaaac
    21961 gtggattcac taacatcaac gctaaagaat acgcaattgt gaaccttgac caattgaacg
    22021 tctttgaaga tggtgctgaa gtaactccag ttgttcttat cgaagcagga attgttaaag
    22081 ctgaaaagtc aggtattaaa attcttggta acggtgagtt gactaagaaa ttgactgtga
    22141 aagcagctaa attctctaaa tcagctgaag aagctatcac tgctaaaggt ggttcagtag
    22201 aagtcatcta agagaggtga cctatgtttt ttaaattatt aagagaagct cttaaagtca
    22261 agcaggttcg atcaaaaatt ttatttacaa tttttatcgt tttggtcttt cgtatcggaa
    22321 ctagcattac agttcctggt gtgaatgcca atagcttgaa tgctttaagt ggattatcct
    22381 tcttaaacat gttgagcttg gtgtcgggga atgccctaaa aaacttttcg atttttgccc
    22441 taggagttag tccctatatc accgcttcta ttgttgtcca actcttgcaa atggatattt
    22501 tacccaagtt tgtagagtgg ggtaaacaag gggaagtagg tcgaagaaaa ttgaatcaag
    22561 ctactcgtta tattgctcta gttctcgctt ttgtgcaatc tatcgggatt acagctggtt
    22621 ttaatacctt ggctggagct caattgatta aaactgcttt aactccacaa gtttttctga
    22681 cgattggtat catcttaaca gctggtagta tgattgtcac ttggttgggt gagcaaatta
    22741 cagataaggg atacggaaac ggtgtttcca tgattatctt tgccgggatt gtttcctcaa
    22801 ttccagagat gattcagggc atctatgtgg actactttgt gaacgtccca agtagccgta
    22861 tcacttcatc tatcattttc gtaatcattt tgattattac tgtattgttg attatttact
    22921 ttacaactta tgttcaacaa gcagaataca aaattccgat ccaatatact aaggttgcac
    22981 aaggtgctcc atctagctct taccttccgt taaaggtaaa tcctgctgga gttatccctg
    23041 ttatctttgc cagttcgatt actgcagcgc ctgcggctat tcttcagttt ttgagtgcca
    23101 caggtcatga ttgggcttgg gtaagggtag cacaagagat gttggcaact acttctccaa
    23161 ctggtattgc catgtatgct ttgttgatta ttctctttac attcttctat acgtttgtac
    23221 agattaatcc tgaaaaagca gcagagagcc tacaaaagag tggtgcctat atccatggag
    23281 ttcgtcctgg taaaggtaca gaagaatata tgtctaaact tcttcgtcgt cttgcaactg
    23341 ttggttccct cttccttggt gtgatttcca ttttaccgat tgcagctaaa gatgtatttg
    23401 gtctttctga tgttgttgcc tttggtggaa caagtctctt gatcattatc tctacaggta
    23461 tcgaaggaat caagcaattg gaaggttacc tattgaaacg taagtatgtt ggtttcatgg
    23521 acaaaacaga ataaaagtat ttactgaatc agtaaatact gagggagtgg aggtttaaac
    23581 tctgacattt gtaagagttg gatctcccct cttctatttt gtttttaaat aggggtgaaa
    23641 agactttttg cttctattta aaaataaaat aaggagatca aatcatgaat cttttgatta
    23701 tgggcttacc tggtgcaggt aagggaactc aagcagcaaa aatcgtagaa caattccatg
    23761 ttgcacatat ctcaacaggt gatatgttcc gcgctgcaat ggtaaatcaa actgaaatgg
    23821 gtgttcttgc taagtcatat attgacaagg gtgaattggt tcctgacgaa gttacaaatg
    23881 gaatcgtaaa agaacgtctt tcacaagatg atattaaaga aacaggattc ttattggatg
    23941 gttacccacg tacaattgaa caagctcatg ccttggacaa aacattggct gaacttggca
    24001 ttgaactaga aggtgttatc aatattgaag tgaaccctga cagcctcttg gaacgtttga
    24061 gtggccgtat catccaccgc gtaactggag aaactttcca caaggtcttt aacccaccag
    24121 ttgactataa agaagaagac tactaccaac gtgaagatga taagcctgag acagtaaaac
    24181 gtcgtttgga tgttaatatt gctcaaggag aaccaatcat tgctcactac cgtgccaaag
    24241 gtttggttca tgacatcgaa ggtaatcaag atatcaatga tgtcttctca gatattgaaa
    24301 aagtattgac aaatttgaaa taaagcgttt ttcacacttg caaaaatccg ctacaaatgt
    24361 tatactgaga tagtctgact tataattgtt gtctctgtgt ctagaggcat cgaatcgaaa
    24421 tttatggagg tgcttttgcg tggcaaaaga cgatgtgatt gaagttgaag gcaaagtagt
    24481 tgatacaatg ccgaatgcaa tgtttacggt tgaacttgaa aatggacatc agattttagc
    24541 aacagtttct ggtaaaattc gtaaaaacta tattcgtatt ttagcgggag atcgtgttac
    24601 tgtcgaaatg agtccatatg acttgacacg tggacgtatc acttaccgct ttaaataatc
    24661 gaaaaacttg gagggataag aaatgaaagt aagaccatcg gtcaaaccaa tttgcgaata
    24721 ctgtaaagtt attcgtcgta atggtcgtgt tatggtaatt tgcccagcaa atccaaaaca
    24781 caaacaacgt caaggataag atagaaagga gaaaacatgg ctcgtattgc tggagttgat
    24841 attccaaatg acaaacgcgt agtaatctca ttgacttatg tttatggtat cggacttgca
    24901 acatctaaga aaattttggc tgctgctgga atctcagaag atgttcgtgt acgtgatctt
    24961 acatcagatc aagaagatgc tatccgtcgt gaagtggatg caatcaaagt tgaaggtgac
    25021 cttcgtcgtg aagtaaactt gaacatcaaa cgtttgatgg aaatcggttc ataccgtggt
    25081 atccgtcacc gtcgtggact tcctgtccgt ggacaaaaca ctaaaaacaa cgctcgcact
    25141 cgtaaaggta aagctgttgc gattgctggt aagaaaaaat aatataggag gtaaaagtct
    25201 tggctaaacc aacacgtaaa cgtcgtgtga aaaagaatat cgaatctggt attgctcata
    25261 ttcacgctac atttaataac actattgtta tgattactga tgtgcatggt aatgcaattg
    25321 cttggtcatc agctggtgct cttggtttca aaggttctcg taaatctaca ccattcgctg
    25381 ctcaaatggc ttctgaagct gctgctaaat ctgcacaaga acacggtctt aaatcagttg
    25441 aagttactgt aaaaggtcca ggttctggtc gtgagtcagc tattcgtgcg cttgctgccg
    25501 ctggtcttga agtaacagca attcgtgatg tgactccagt gccacacaat ggtgctcgtc
    25561 ctccaaaacg tcgccgtgta taatcatcgc attacactgc ttttcgttta agagggagta
    25621 actaaatgat cgagtttgaa aaaccaaata taacaaaaat tgatgaaaat aaagattatg
    25681 gcaagtttgt aatcgaacca cttgaacgtg gctacggtac aactcttggt aactctcttc
    25741 gtcgtgtact tctagcttct ctaccaggag cagctgtgac atctatcaac attgatggtg
    25801 tgttacatga gtttgacaca gttccaggtg ttcgtgaaga cgtgatgcaa atcattctga
    25861 acattaaagg aattgcagtg aaatcgtacg ttgaagacga aaaaatcatc gaactggatg
    25921 ttgaaggtcc tgctgaagta acagctggtg acattttgac agatagcgat attgaaattg
    25981 taaatccaga tcattatctc tttacaatcg gtgaaggttc ttctctaaaa gcgactatga
    26041 ctgttaacag tggtcgtgga tatgtacctg ctgatgaaaa taaaaaggat aatgcaccag
    26101 ttggaacact tgctgtagat tctatttata caccagttac aaaagtcaac tatcaagtgg
    26161 aacctgctcg tgtaggtagc aatgatggtt tcgacaaatt aacccttgaa atcttgacaa
    26221 atggaacaat tattccagaa gatgctttag ggctttcagc acgtattttg acagaacatc
    26281 ttgatttgtt tacaaatctt actgagattg ctaagtcaac tgaagtgatg aaagaagctg
    26341 atactgaatc tgacgaccgt attttagatc gtacgattga ggaactggac ttgtctgtgc
    26401 gttcatacaa ctgtttaaaa cgtgccggta tcaatactgt gcatgatttg acagaaaaat
    26461 ctgaagcaga gatgatgaaa gtacgaaatc ttggacgcaa gagtttggaa gaagtgaaac
    26521 tcaaactcat tgatttgggt cttggattaa aagataaata aaggaggaat acatggctta
    26581 ccgtaaacta ggacgcacta gctcacaacg taaagcaatg cttcgcgatt tgacaactga
    26641 ccttttgatc aacgaatcaa tcgtgacaac tgaagctcgt gctaaagaaa tccgtaaaac
    26701 tgttgaaaaa atgattactc taggtaaacg tggtgatttg catgcacgtc gtcaagcagc
    26761 tgctttcgta cgtaatgaaa tcgcatctga aaactatgat gaagcaactg ataagtacac
    26821 ttctactaca gcacttcaaa aattgttctc agaaatcgca cctcgttatg ctgaacgtaa
    26881 cggtggatac actcgtatcc ttaaaactga accacgtcgt ggtgatgcag cgccaatggc
    26941 gatcatcgaa ttagtataaa atcatcaatt ttgttgagtg ttatgatgat ggagtcttgt
    27001 gctcttagtc tagctctggt ctaccgctag gatttcggtc ctagcgggaa cactcatcat
    27061 aagttgggat agtagacgct tgtttacgaa attgtttttt tcttaagaac aacttcgtaa
    27121 gcaggcgttt ttgagtattt tcgttagaat tatgctatac tatttgaaaa gaatcctgtt
    27181 taatgttaag gtttcttatt ttaagaagaa ttggagttta cttatgaaag ccattataac
    27241 tgttgttggt aaagataaat ctggaattgt tgcaggtgtt tctggtaaaa ttgcagaatt
    27301 aggattgaat attgacgata tctctcaaac tgtcttggat gaatatttta cgatgatggc
    27361 tgttgtatct agtgatgaaa agcaagattt tacctatctt cgtaatgaat ttgaagcttt
    27421 tgggcaaact ttgaatgtaa aaatcaatat tcagagtgca gcgattttcg aagctatgta
    27481 taatatctag gaggtcatca tggatattag acaagttact gaaaccatcg ccatgattga
    27541 ggagcaaaac ttcgatatta gaaccattac catggggatt tctcttttgg actgtatcga
    27601 tccagatatc aatcgtgctg cggagaaaat ctatcaaaaa attacgacaa aggcggctaa
    27661 tttagtagct gttggtgatg aaattgcggc tgagttggga attcctatcg ttaataagcg
    27721 tgtatcggtg acacctattt ctctgattgg ggcagcgaca gatgcgacgg actacgtggt
    27781 tctggcaaaa gcgcttgata aggctgcgaa agagattggt gtggacttta ttggtggttt
    27841 ttctgccgta gtacaaaaag gttatcaaaa gggagatgag attctcatca attccattcc
    27901 tcgcgctttg actgagacgg ataaggtctg ctcgtcagtc aatatcggct caaccaagtc
    27961 tggtattaat atgacggctg tggcagatat gggacgaatt atcaaggaaa cggcaaatct
    28021 ttcagatatg ggagcggcca agttggttgt attcgctaat gctgttgagg acaatccatt
    28081 tatggcgggt gcctttcatg gtgttgggga agcagatgtt atcatcaatg tcggagtttc
    28141 tggtcctggt gtggtgaaac gtgctttgga aaaagttcgt ggacagagct ttgatgtagt
    28201 agccgaaaca gttaagaaaa ctgcctttaa aatcactcgt atcggtcaat tggttggtca
    28261 aatggccagt gagagactgg gtgtggagtt tggtattgtg gacttgagtt tggcaccaac
    28321 ccctgcggtt ggagactctg tggcacgtgt ccttgaggaa atggggctag aaacagttgg
    28381 cacgcatgga acgacggctg ccttggccct cttgaacgac caagttaaaa agggtggagt
    28441 gatggcctgc aaccaagtcg gtggtttatc tggtgccttt atccctgttt ctgaggatga
    28501 aggaatgatt gctgcagtgc aaaatggctc tcttaattta gaaaaactag aagctatgac
    28561 ggctatctgt tctgttggat tggatatgat tgccatccca gaagatacgc ctgctgaaac
    28621 cattgcggct atgattgcgg atgaagcagc aatcggtgtt atcaacatga aaacaacagc
    28681 tgttcgtatc attcccaaag gaaaagaagg cgatatgatt gagtttggtg gtctattagg
    28741 aactgcaccc gttatgaggg ttaatggggc ttcgtctgtc gacttcatct ctcgcggtgg
    28801 acaaatccca gcaccaattc atagttttaa aaattaagaa aataggagaa attttaagtt
    28861 ctatttaaga ttagacgtgt atactataat cattaaataa agacctccta atattatttg
    28921 aaacagataa cattgaatta gtttgaattt gattttcatc taatatcttt atttaatgaa
    28981 ctcctaaact ttttcataat aatctccttc aaaagtcgcc tgtatgggtg gcttttattt
    29041 tatcattcat gatataatag aagcaaacgg aggacggaaa atggtaaaag tacgattgta
    29101 tttggtacgt catggcaaga ccatgtttaa cacgattggt cgcgcgcaag gttggagcga
    29161 tactccctta actgctgaag gtgaacgagg gattcaagag ttaggaatcg gtttgcgaga
    29221 atctgatcta cagtttgagc gcgcttattc gagtgattct ggtcgtacca ttcagaccat
    29281 gggaattatc cttgaagagc ttggcttgca ggggaaaatc ccttatcgca tggacaagcg
    29341 tatcagagaa tggtgtttcg gtagttttga tggagcctat gatggcgatc ttttcatggg
    29401 cattattcct cgtatcttta atgtggacca cgttcaccaa ttgtcttatg ctgaactggc
    29461 tgagggcttg gtagaggtcg atacagctgg ttgggctgaa ggctgggaaa aactcagtgg
    29521 ccgaatcaag gaaggctttg aaatgattgc aaaagaaatg gaagatcaag gtggaggtaa
    29581 cgcccttgtt gtcagccatg gaatgactat tggaaccatt gtttatctga ttaatggcat
    29641 gcatccgcat ggtctagata atggtagcgt gacgattctt gaatatgagg gcggtcagtt
    29701 tagggttgaa gttgtcggtg accgtagtta ccgagagcta ggacgtgaga agatggaaga
    29761 aggctctatt taatcagtct agacttgctt gccatgagct agggatttga taagaatatc
    29821 aagataagaa aaaacagccg agggcactcc tttcggctgt ttttgatgtg gaaaactaaa
    29881 gggtaaagct attgctttta gagattttca taaacaagag caaggaacct actgttagaa
    29941 cagtcaggat agttgacaag gctgcggcta caccgtaatt tcctctgaga acctctgtat
    30001 aaatagctac agtcattgtt cttgttttga cattgtagag gaggatagaa gtagagagtt
    30061 ttgaaatcat tgtgacccaa gataagatga ctccagaaat aatacccgat agcatcattg
    30121 gagttgtaat cttagcaaag atattgagac gactacttcc taagctttca gcagcttctt
    30181 caatacttgg tgctatttgt tgtaagctag caacagatga gcgaatagta tacggtaatc
    30241 ttctgacaga tagagacata atcaagatga aagcagtccc tgtaatcata agaaatccac
    30301 ttccaaatag accagtattg aaggaagaaa tgaaggcaat ccctagaacg gttcctggta
    30361 caatataagg taccatactg aggctgtcaa ttaagtttgt aaacaaattc cgttttctaa
    30421 cggctaggta ggagataaat gtcgcaaata gaacaactag aactaaggca atcaaaggga
    30481 tacgaatggt attgaaaata gcagatccca tacgattgaa agctaccttg taactgtttg
    30541 gagaataacc tttaacaaat accatacctg atgtttttag gaaagaggta taaattaagt
    30601 agatttgagg taaaacagag ataaagataa ttccgtagac tgttgcataa atggcagcca
    30661 tttttccttt tgtagttttt ttaggctcaa ttggatggag cagattcatg ctgaaactgt
    30721 agcggtttgc aatgtgtttt tggataagga aaattgccaa ggcaatgata atcgccataa
    30781 ttgcaaaagc agaatttcct ccaacctcgc taataaattg ggtataaatc aggacaggga
    30841 aagtccgata tccttcgcca atcaacatag gcgttccaaa gtctgagaat gctctcataa
    30901 atacaagcaa ggagctgcta gtaaggttgg aactaggaga ggtaaaacaa ccgttacgat
    30961 aggtttaaat ccgaaggacc ccatgctttc agctgcttca agtagagaat tgtcaatact
    31021 gttcattgtt ccagcaacat atagaaatac cagtgggaat agttgcagtg taaagacaag
    31081 tacaattcct ttgaatccat aaatatcgat agctggaaga tgaagggcat ttgtcaaaaa
    31141 tttagtgatg accccatttc gtcccagcaa gagaacccag gagtaggctc ctacgaaagg
    31201 agctgacatg gaagcaatga taatcaatat ttgtagaaat ttcttcccct tgaagtcata
    31261 catagagaag agataagcta atagggttcc tacaactaag gaagtgacag tagcggtaat
    31321 ggaaaccctg aaactgttga ctagtgtctc agagtagtag gctttactaa agaaagtgac
    31381 aaaattagct agtgagaatt gtccttcatg tataagtgct tgcttgagca cggtaacgat
    31441 aggataaacg agaaagacaa gataggtaag aaagatgaag aaagaggaag ctgtccaaat
    31501 atttagtttt ttacattcca tggttgactc cttttatcag gttttgggaa ccatctgcag
    31561 aaaagatgtt taatttttgc gtattgattc gtagacgaat acgattgcct ttttgtagtt
    31621 cttcttcaaa agttgattct tcactaactt aaatttttga ggcaaaacct gtctcaatga
    31681 aatactccgt atttagtcca agatagacgc tatcgctaat agttccttcg atatctccag
    31741 atttatcttt gataaactct tcgggacgaa tgcttacatg aatagcttgc tcctcaacct
    31801 gatcaagagc tggcattcga agggcatagc catctgaaaa gacgatataa gcgccgtcgc
    31861 tccgtttttc aagattggca gggataatat ttgtgcgtcc gataaaggtt gccacaaact
    31921 cattagctgg tttatgatag agttattttg gtcagccgat ttgttggatc accccatctt
    31981 tcataacagc aatttggtct gaaatagcca tggcttcttc ttggtcgtgg gttacataaa
    32041 cagttgtaat tcccacttcg tgttggattt ctcggatggc ttgacgcata tccaagcgaa
    32101 gtttggcctc cagattacta agtggctcgt ccatgaggag aacacttgga ttaaccgcta
    32161 aggcgcatgc caaggtgaca cgttgttgtt gtccaccact gagtttatcg ggctttcgat
    32221 ccgcatattg agcaatttgc atgagttcaa gatacttgtt ggtctgttga atcaattctt
    32281 cttttggaac cttcttttgc ttaagaccaa aagcaacgtt gtctcggaca gtcaaatgtg
    32341 ggaaaatagc gtagttttgg aaaaccatcc cgatattgcg tttgctggat tccatattat
    32401 tgatttttgt atcatcgaag tattgatact gttgaaacct gcaatcatac gaagaagggt
    32461 cgttttcccg catcctgaag ctccaagaag ggtaaagaga cttccttttg gaattgtaat
    32521 gttcaaattc tcaataacag ggacatcgtg gtagattttt ttggcgttaa taatttcgat
    32581 ctcactcata gtgaacctct tttactgttt agattggata tctgtaaaga cttcgttgta
    32641 tttcttaacg atatctgatt tattcttgat gacataatca taatcttcag tgagtgtttt
    32701 gattttgtca attggtttca tgttttcgct tgttttagca tttttacgaa caggacggtt
    32761 agtagtggtt gtaccaagtg tatcttgtac ttcttgagag ataataaaat cgataaattt
    32821 cttggcattt tccatatttt tagatttttt aacgatagca gcactagcag gtaggaagac
    32881 ggttccttct tttggataga ctaccttaat gttagctccg tcatttaaga gtttaactgc
    32941 tggatcttca taagagagac caacagtcat ttctacatca gcgactgctt tatagacacc
    33001 agatgaactt aaaccgattt tatagtatat tgaaactaga atagtacaca tctgcttcta
    33061 aaacattgtt agaaatcgat ttgactgtcc tgattaattt gtcctattct tatttcattt
    33121 tactatacca tcaataagtg tgaaaagatc ttttacataa gaccaagcct tatcatcttt
    33181 gtaaccacct tgagcttgta gcatatttgt taattgagca aaggcgctag aagagtttgc
    33241 tgggtcagca gttgcgattt ttccttttag ttcaggtttg agaaggtcgc tatatccttc
    33301 gatgttcatg cctttagtta aatcagggtg gacgattaaa acactaccat ctagtgtata
    33361 aggagtagag aagccagttg tgttttgata ttctttgata acattatcat tttcttttga
    33421 aatatagttt tcaaagagtt ctccgtgggt agcatattgt gtataagaac caccaaagat
    33481 aacatcagct acaggaactt ctttttctga ctctagtttt ttgaaaagtt ctccagtacc
    33541 agcttgaatc agttctattt tgataccata tttttcttca aaggcaggaa tagttgctcc
    33601 aattaagtcc tctgagtttg gtcaataaac gactagcgaa ccaccgtctc ctttatcaga
    33661 tgaactgtca tcggcagatt cattagaaga acaagcagca taatacatcc atttcttttt
    33721 catgatggga tatctccgtt gtgttattta agtttatttt aaaaaaatgt aagcgttttt
    33781 aaaacctaca attctattct atagtgtatt gaatctataa cagtacactt tgactgctaa
    33841 aatatttcta taaattaatt tgactttcct gatagagatg ttcacatctt atttcaattc
    33901 actatattag agtaaaattc tctacaaaaa gaagaatagc ctattttact attcttccga
    33961 gtgatttcaa tttctttggg gaaatatgga gatacttttt aaatactttg gcaaaatatt
    34021 tatagtctga aaatccaact tggtcagaga tagcgcttaa aggggagttg ggagattcag
    34081 ccatcttatc tatagcttgt ttcaggcgat attgtaagat atattcattt agagtcatgg
    34141 ggaagtcttc tttgataacc ttatatagat gcttgttatc tgcaaatagc tagagcattt
    34201 caaggaaata aactagaaat aacaattaat atggtggttc agaaatacct tttgataatc
    34261 aataagatct tcaggatgaa gtgcgttgat tccatccatt tcatatttcc gatttaataa
    34321 acgatatttg ttttcaccaa attgatgaaa agggagtagt tgaacttggt cgatatttaa
    34381 tgagttaaat agagtagcga atttttctgc atcctctaaa ctattgttaa aattaggaat
    34441 aactgggatt cttaaaacga tagttttatt ttgagaaaaa gcataatgaa tgtttttaat
    34501 aatcatttga ttaaaaaccc cagtcacttt tttatgtttt atagaattat aatgttttag
    34561 gtctgtgtag ataaaatcca catattgaat taaatcaata aatttttcat gatcaacaaa
    34621 ggcagtagtt tcaatggcag tgtgtatgtg atgttcttta gctgatttta agatggcttt
    34681 agcaaattca aactgagcaa atatttcacc tcctgataaa gttaaacctc caccggattc
    34741 ttcgtaaaat tctttgtctt ttaatacctc tgtaataatt tcttctacag tcttttcttc
    34801 accgactaag gtgaatttct ctcgttgagc atctttcatt ttttcaggtt tcattctttg
    34861 agattcagga ttagaacacc atggacagcg cagaggacat ccttttaaaa aaacagttgt
    34921 acgaataccc gggccgtcat gaattgaaaa gtgttgaata ttaaaaataa ttcctttaga
    34981 tatttccata agagttcctc ctcttcataa gtctatccta tcacaaaaac gaaagaaaaa
    35041 caattacgaa cgaaagttta atttgttgtt ttttgctttt tattttggta gaataaaacg
    35101 gaggtgtaaa atgaaaagat tggaacaaat tattaaatta gtatcagaat atgaaaagat
    35161 cgacgttaat acattatcgg aaaaattaaa tgtatcgaaa gtaacgatta gaaaagattt
    35221 agataaatta gagtcaaaag gtttattaca cagagagcat ggatatgctg tattaaatag
    35281 tggagatgac ttaaatgtac gtttgtcaat taactatgaa attaagagaa aaattgttca
    35341 ggaagcagta aaattggtgt cagataatga aacaataatg atagaatctg gatcgacctg
    35401 tgctttactt gctgaggaaa tttgcaagca aaaaagaaat gttacgattg taacaaattc
    35461 attttttata gcaaattttg tgagagctta tgattcatgt cgtattattg ttcttggtgg
    35521 agagtttcag aaggattcac aggttactgt gggaccttta ttaaaagaaa tgatacagac
    35581 ttttcatgtg catcaagctt ttgttgggac agatggttac gataaagaga tgggctttac
    35641 aggaaaagat ttaatgcgca gtgaggtagt tcaatatatt tcagcagcgt cggataaagt
    35701 cattgtacta actgactcaa gtaaatttga taaaaggggt acagtaagaa gatttgcttt
    35761 aagtcaagtc tatgaagtaa taacagacga aaaactttct aaacaaaata tagctacatt
    35821 agaaaatgct gggataatgg ttaaggtagt ttcgtaagag gttaaatgta tgaatcaaga
    35881 taggaataaa ctgctctcta aaattgctta tctgtattat attgaaaact taaatcagtc
    35941 acaaatagca gcaaaattag gaatttatag aacctctatt agtagaatgt taacagaagc
    36001 aaggaatgca ggaattgtta aaattgaaat agagaatttt gataccaata tgtttaagtt
    36061 ggaaaattat gtaaaagaaa aatatggtct ggaaagttta gaaattattc caaatgaatt
    36121 tgatgataat ccaacaattt tatctgaaag aatttctcaa gttgcagcag gtgtccttag
    36181 gaatctaatt gatgataata tgaaaattgg cttttcttgg gggaaaagtt taagtaattt
    36241 agtagattta attcacagta aaagtgtccg aaatgttcac ttctatcctc tagcaggtgg
    36301 tcctagtcac atacacgcta aataccatgt gaatacactg atttatgaaa tgtctagaaa
    36361 atttcatgga gagtgtacat ttatgaatgc aacgattgtg caagaaaata aattgttagc
    36421 agatggtatt ttgcaatcaa gatattttga aaatttgaaa aatagttgga aagatttaga
    36481 tatagctgta gtcggaattg gtgattttag caataaagga aagcatcaat ggttagacat
    36541 gcttacagag gatgacttta aagaattgac caaagttaaa actgtaggag aaatttgttg
    36601 tcgatttttt gattcaaaag gtaaagaagt ctatgaaaac ttacaggaaa gaacgatagc
    36661 aatctctttg gaagatttaa aaaatattcc tcaaagttta gctgttgctt acggtgatac
    36721 gaaagtatct tcgattcttt ctgtcttgcg tgctaattta gtaaatcatt tgattacaga
    36781 caaaaataca attttaaaag ttttggaaga agatggggat ttgactttta gagagattct
    36841 aggtgagtga aaatgataga ctgattcagt ttatcgtttt tctttttagt tgattgcaca
    36901 tttgtgctta tataaacaaa aatagtttat ctgttgtttt tggattgaca actttattat
    36961 gtagttgtat tctatagtta caaaagaaaa ttttaaaatt tcaaatgaaa aaagcttttt
    37021 acatagtgaa atgaggagga atttatggaa attattgttc cagatcaaat tatcatgggt
    37081 ttaattttat atgctggtga tgcgaaacaa catatttata aagcgttaga ttacataaaa
    37141 aatggtacat gtgaacggtg tgaagaagaa atccagttag ctgatgcagc cttattagaa
    37201 gctcataatc tacaaacaaa attcttggca caggaagcgt ctggtacaaa gacagaaatt
    37261 acagctctct ttgttcattc acaagatcat ctcatgacta gtatgacgga gattaattta
    37321 atcaaagaaa ttattagttt gagaaaagaa cttcataaaa aataatacta gagtattatc
    37381 attgttatta acatagagga ggaaaacata atggtgaaga ttggtttgtt ttgtgcagca
    37441 ggtttttcta ctggtatgct tgtaaataat atgaaaattg cagcgcaatc tagtggagtt
    37501 gaggcagaaa tagaggcgtt ttctcagtct aaattagcgg attatgcgcc aaatatagat
    37561 gttgcactat tgggtccaca agttgcttat acattagata aatcaaaaga aatttgtgat
    37621 aagtgtgatg ttccgatagc tgttattccg atgatggact atggtatgtt agatgggaaa
    37681 aaagtattag atttggccct atctttgatt agtgggtaag aaaaggagat ttattatgtc
    37741 aaagatggat gttcagaaaa tcattgcacc gatgatgaag tttgtgaata tgcgtggcat
    37801 tatagctcta aaagatggga tgttagcaat tttgccattg acagtagttg gcagtttgtt
    37861 cttgattatg ggacaattgc cgttcgaagg attaaataag agcattgcta gtgtttttgg
    37921 agctaattgg acagagccgt ttatgcaagt atattcagga acttttgcta ttatgggtct
    37981 aatttcttgt ttttcaattg cctattctta tgctaagaat agcggagtag aggctttacc
    38041 agctggagtt ctatctgtat ctgcattctt tattttgcta agatcatctt atatccctaa
    38101 acaaggtgag gcgattgggg acgctattag taaagtttgg tttggaggcc aaggaattat
    38161 cggtgctatc attataggtt tggtagtagg aagtatttat accttcttta taaagagaaa
    38221 aattgttatt aagatgccag aacaagttcc acaagctatt gccaaacagt ttgaagcaat
    38281 gattccagca tttgtaattt tcttatcttc tatgattgta tatattttag cgaagtcatt
    38341 gactaatggc ggaacattca tagaaatgat ttattctgct attcaagttc cgttgcaagg
    38401 tttaactgga tctttgtatg gtgctattgg aattgcattc tttatatcat ttttgtggtg
    38461 gtttggtgtt catgggcaat cggtagtaaa tggagtagtg acagctctgc ttttatctaa
    38521 tcttgatgct aataaagcta tgttagcctc tggtaatcta tcattagaaa atggtgcaca
    38581 tattgttact caacaatttt tagattcatt tttaattcta tcaggttcag ggattacgtt
    38641 tggtcttgta gttgccatgc tttttgcagc aaaatcaaaa caataccaag ccttaggaaa
    38701 agttgcagct tttccagcaa tatttaacgt aaatgagcca gttgtatttg gatttccgat
    38761 tgtcatgaat ccagttatgt ttgtaccttt cattcttgtt cctgtacttg cagctgtgat
    38821 agtatatgga gctattgcaa caggtttcat gcagccattc tcaggggtaa cattgccttg
    38881 gagtacacca gctattctat caggattttt ggtgggtgga tggcaaggtg ttgtgactca
    38941 gttattagta ttggtgatat ctacagtggt ttactttcca ttctttaaga tacaagatcg
    39001 tttagcttac caaaatgaaa tcaaacaatc ttagaggtat ttgtgtgtta ctgttaaact
    39061 cacacatttg tgctaaaaat tagagagtta aaatttttct agttaaaagc ttgaaaattt
    39121 ctataaaaat cggtattata ttttcgaaag aaataaaaat attttcgaaa gaaaggtggt
    39181 tacgatggta aatacagaag tagcaagaac aacaatcaag acagaatatt ttggcagcct
    39241 tactgaaagg atgaacaaat atcgagaaga tgttttaaat aaaaaacctt atattgatgc
    39301 tgagagagca gttctagcaa cacgcgccta tgaacgatac aaggaacaac ctaatgtcct
    39361 aaaacgtgca tatatgctga aagaaatttt ggaaaatatg tctatctata ttgaagaaga
    39421 atctatgatt gcgggaaatc aagcttcttc caataaagat gctcctattt ttccggaata
    39481 tacgctagaa tttgttctca atgagttgga gctttttgaa aagcgtgatg gagatgtttt
    39541 ctatattaca gaagaaacaa aagaacaact tagaagtatt gctccgtttt gggaaaataa
    39601 taatttacgt gctagagctg gtgccttatt acctgaagaa gtgtctgttt atatggaaac
    39661 aggattcttc ggtatggaag gtaagatgaa ttctggagat gctcacttag cagttaacta
    39721 tcagaaactt ttgcaatttg gtttaagagg ttttgaagag cgggctcgta aagcaaaagt
    39781 agctctagat ttaacagatt cagcaagtat tgataaatat catttttacg actctatatt
    39841 tatcgtaatc gatgctatta aagtatatgc aaagcgcttt gttgctcttg ctaaaagttt
    39901 agccgaaaat gcaaatccta aacgtaagaa agaattactt gagattgcag atatttgctc
    39961 tagagtccca tatgaaccgg caactacttt tgcagaagct attcaatcag tttggtttat
    40021 tcaatgtatt ttacaaattg aatctaatgg ccactctctt tcatatggcc gttttgatca
    40081 atatatgtat ccatatatga aggctgattt agaaagtggt aaagaaacag aagatagcat
    40141 tgttgaacgt ctgacaaatc tttggattaa gacaattaca atcaataagg ttcgcagtca
    40201 atcacataca ttttcttcag caggaagtcc tttatatcaa aatgttacaa ttggtggaca
    40261 gactcgagat aagaaggatg ctgttaaccc attatcttat ttggtattaa aatcagttgc
    40321 acaaacccat ctaccgcaac ctaatctaac tgtacgttac catgcaggtt tagatgctcg
    40381 tttcatgaat gagtgtattg aagtgatgaa acttggtttt ggtatgcctg catttaataa
    40441 tgatgagatt attattcctt cttttattgc aaaaggagta ttggaagatg atgcttatga
    40501 ttacagtgcc attggatgtg ttgaaacggc agttccaggg aaatggggct atcgttgcac
    40561 aggtatgagt tatatgaact tccctaaggt tctacttatc acgatgaatg atggaattga
    40621 tccggcttcg ggtaaacggt ttgcaccaag ctttggtcat tttaaggata tgaagaactt
    40681 ttctgaatta gaaaatgctt gggataaaac actaagatat ttgacacgaa tgagtgttat
    40741 tgttgaaaat tctattgatt tatcattgga acgagaagtt cctgatattc tatgttcagc
    40801 attgactgat gattgtattg gtcgtggaaa acaccttaaa gaaggtggag cagtatatga
    40861 ttatatatca ggattgcaag ttggaattgc aaatttgtcg gattcattag ctgcaattaa
    40921 aaaattggtg tttgaggaag aacgtataag cccaagtcag ctttggcatg cactggaaac
    40981 agattatgcc ggagaagaag gtaaggtcat tcaagaaatg ttgattcatg atgcacctaa
    41041 gtatggtaat gatgatgatt atgctgacaa attggttact gctgcttatg acatttatgt
    41101 tgatgaaatt gctaaatatc ctaatacacg ttatggaaga gggcctattg gaggaattcg
    41161 ttattcagga acatcttcta tatcagccaa cgtagggcag ggacgtggaa cattagcaac
    41221 tccagatgga cgcaacgcgg gtacaccgtt agcagagggt tgttcaccat cacataatat
    41281 ggatcaacac ggccctacat ctgttttaaa atctgtttca aaattaccaa cagatgaaat
    41341 cgtaggtggg gttctcttaa atcagaaagt aaatcctcaa acgttagcca aagaagaaga
    41401 taaattaaaa ctaattgctt tgttacgaac attctttaat cgtttacatg ggtaccatat
    41461 tcaatacaat gttgtttcca gagagacgtt gattgacgct cagaaacatc ctgaaaaaca
    41521 cagagactta attgttcgtg ttgcaggata ctctgcattc ttcaatgttc tttctaaggc
    41581 aacccaagat gacattatag gacgtactga gcatactttg taaaataaag aggttctttt
    41641 tatggaattt atgcttgaca cattaaattt agatgagatt aaaaagtggt ctgaaatttt
    41701 gccgctagct ggggtaactt caaatcccac tattgcaaaa agagagggtt ctattaattt
    41761 ttttgaacga atcaaagatg taagagaatt gattggctct acaccctcta ttcatgttca
    41821 ggtgatttct caagattttg aaggcatctt aaaggatgct catgaaattc gaagacaagc
    41881 aggagatgat atatttatca aagtacctgt tactccagct ggattacgtg caataaaggt
    41941 gctaaaaaaa gagggctacc atatcactgc aacagctatt tatacagtta ttcagggatt
    42001 attagctatc gaagtaggag cggattacct agctccatat tataatagaa tggaaaatct
    42061 gaacattgat tcaaattctg tcattcgtca attagctctt gctattgata gacagaactc
    42121 tcctagtaag attttagctg catcctttaa aaatgtagca caagtaaata atgctttagc
    42181 tgcaggtgcg catgctgtta cagcaggagc agatgttttt gaatcagctt tcgccatgcc
    42241 atctatccaa aaggcggttg atgacttttc tgacgactgg tttgttattc aaaatagtcg
    42301 ttccatttag atagagagga aatacatatg agaatttttg ctagtccttc tagatatatt
    42361 cagggggaaa atgccttgtt tgaaaatgcc aaatcaattt tggatttggg aaattgccct
    42421 attctattat gcgatcagtt ggtttatgat attgttggaa aacgatttga agattaccta
    42481 cataggtatg gtttccatat tgttctggcg ctatttaatg gtgaagcttc tgacaatgaa
    42541 atcaatcgag ttgttgcctt ggctgagaaa gaaaattgtg atagtattat cggtcttggt
    42601 gggggaaaga cgattgatag cgcaaaagct attgcagatt tgattgaaaa gcctgttatt
    42661 attgctccaa caattgcatc gaccgacgca cctgtatctg ctttatctgt tatttataca
    42721 gatgaaggtg catttgatca ttatctattt tattctaaaa atccagattt agttttggtt
    42781 gatacaaaag ttatttcaca agcccctaag cgtttattag cgtctggtat tgcagatggt
    42841 ttagcaactt gggttgaggc gcgtgcggtt atgcaggcaa atggaaaaac tatgttggga
    42901 caacagcaaa cattggctgg agttgcaatt gcgaagaaat gtgaagaaac gctgtttgca
    42961 gatggtttac aggctatggc agcttgtgaa gctaaagtgg tgacaccagc attagaaaat
    43021 attgttgaag ctaatacttt attgagtggc ctaggttttg aaagtggagg attagctgcg
    43081 gcgcatgcaa ttcataatgg ttttactgca ttgacaggtg acattcatca tttaacacat
    43141 ggtgaaaaag tagcttatgg aactttagta caactattat tggaaaatag acctaaagaa
    43201 gaacttgata agtatattga gttttacaaa aaaattggta tgccaacaac tctaaaagaa
    43261 atgcatttgg atcaagttgg atatgatgat ttaataaaag ttggtaaaca agcaactatg
    43321 gagggtgaga caattcatca gatgccgttt aagatttcgc cttcagatgt tgctcaagct
    43381 attatcgctg tagatgccta tgtaaattca aaataaacaa taaggactac tgttttccaa
    43441 atgatagtct tttattgatc ctcgtattga attctatagc agattgaaat aagatgagaa
    43501 caaatcgatt gggaaagtaa aattaatttc taacaatgtt ttagcaattg tttcgtacta
    43561 tttcagattc agtccactat acgttcttca taaatcaaaa agcgacatag gttgtcggct
    43621 atttattgtg aatacattaa ttagcattcc agttttatct tcggtctaaa ataagtattt
    43681 tgtgctatac gagataagcg tcttgactta ctccttgatt tactgcataa caatgggata
    43741 aaaagtggga gatagagcaa ttcatagtca tcaaaattaa tgagatacag tatacagttt
    43801 ttcctttaaa cacatttcaa attccctcaa aaatggtata atagtaacat cacaaaattg
    43861 gagagagacc atgagttttt acaatcataa agaaattgag cctaagtggc agggctactg
    43921 ggcagaacat catacattta agacaggaac agatgcatca aaacctaagt tttatgcgct
    43981 tgatatgttc ccttatccgt ctggagctgg tctgcacgta ggacacccag aaggttatac
    44041 tgcaaccgat atcctcagtc gttacaaacg tgcgcaaggc tacaatgtcc ttcacccaat
    44101 gggttgggat gcttttggtt tgcctgcaga gcaatacgct atggatactg gtaatgaccc
    44161 agcagaattt acagcggaaa acattgccaa cttcaaacgt caaatcaatg cgcttggatt
    44221 ttcttatgac tgggatcgtg aagttaacac aacagatcca aactactaca agtggacgca
    44281 atggattttc accaagcttt acgaaaaagg cttggcctat gaagctgaag tgccagtaaa
    44341 ctgggttgag gaattgggaa ctgccattgc caatgaagaa gtgcttcctg acggaacttc
    44401 tgaacgtgga ggctatccag ttgtccgcaa accaatgcgc caatggatgc tcaaaatcac
    44461 ggcttacgca gagcgcttgc tcaatgactt agatgaacta gattggtcag agtctatcaa
    44521 ggatatgcaa cgcaactgga ttggtaaatc aactggtgcc aatgtaactt tcaaagtaaa
    44581 aggaacagac aaggaattta cagtctttac tactcgtccg gacacacttt tcggtgcgac
    44641 tttcactgtt ttggctcctg aacatgaatt agtagatgcc atcacaagca cagagcaagc
    44701 agaagcagta gcagactaca aacaccaagc cagccttaag tcagacttgg ctcgtaccga
    44761 ccttgccaaa gaaaaaactg gtgtatggac tggtgcttat gccatcaatc ctgtcaatgg
    44821 taaggaaatt ccaatctgga ttgcggatta cgttcttgct agctatggta caggtgcggt
    44881 aatggctgtg cctgcccacg atcaacgtga ctgggaattt gccaaacaat ttgaccttcc
    44941 aatcgtcgaa gtacttgaag gtggaaatgt tgaagaagct gcctacacag aagatggcct
    45001 tcacgttaat tcagacttcc tagatggact caacaaagaa gacgctattg ccaagattgt
    45061 ggcttggttg gaagaaaaag gctgtggaca agagaaggta acctaccgtc tccgcgactg
    45121 gctctttagc cgtcaacgtt actggggtga gccaatccca atcattcatt gggaagatgg
    45181 aacttcaaca gctgtccctg aaagtgaatt gccacttgtc ttgcctgtaa ccaaggatat
    45241 ccgtccctca ggtactggtg aaagtccact agctaacttg acagactggc ttgaagtgac
    45301 tcgtgaagat ggtgtcaaag gtcgtcgtga aacaaatact atgccacaat gggcaggttc
    45361 aagctggtac tacctccgct atattgaccc acacaatact gagaaattgg ctgacgagga
    45421 tctgctcaaa caatggttgc cagtagatat ctacgtgggt ggtgcggaac atgctgtact
    45481 tcacttgctt tacgctcgtt tctggcataa attcctctat gacctcggtg ttgttccaac
    45541 taaggaacca ttccaaaaac tctttaacca aggaatgatt ttgggaacaa gctatcgtga
    45601 ccaccgtggg gctcttgtgg cgactgacaa ggttgaaaaa cgtgatggtt ctttcttcca
    45661 tgtggaaaca ggggaagagt tggagcaagc gccagccaag atgtctaaat cgctcaagaa
    45721 cgttgtcaac ccagacgatg tggtggaaca atacggtgct gatacccttc gtgtctatga
    45781 aatgttcatg ggaccactcg atgcttcgat tgcttggtca gaagaaggtc tggaaggaag
    45841 tcgtaagttc cttgaccgtg tttaccgttt gattagaagt aaggaaattg ttgcggaaaa
    45901 caatggcgct cttgacaagg tttacaacga aactgttaaa gctgtcacag agcaaattga
    45961 ttccctcaaa ttcaacacag ccattgccca acttatggtc tttgtcaatg cggctaacaa
    46021 ggaagacaag ctctatgttg actatgccaa aggatttatc caattgactg ccccatttgc
    46081 acctcacttg gcagaagaac tctggcaaac tgttgctgca acaggtgagt caatctctta
    46141 cgtgacttgg ccaacatggg acgaaagtaa actgattgaa gacgaaatcg aaatcgttgt
    46201 ccaaatcaaa ggtaaagtcc gtgccaaact catggtcgct aaagacctat cacgtgaaga
    46261 attgcaagaa attgctctag cggatgaaaa agtcaaagca gaaattgacg gtaaggaaat
    46321 cgtgaaagtg attagtgtac caaataaatt ggttaatatt gttgtaaaat aaccaattta
    46381 tttgctgatt tccaacctca aacagtttcc taaactgttt gagccaacta aactcgttaa
    46441 tatcgttgtg aaataaggta ggaatccttc agagtagaat ctggaggatt ttttgaatct
    46501 tcttatgaaa gtatggtata ctatgggcaa ctataaagtt tgaaaagtga aaaaaggaga
    46561 aagctatgcc agtaaatgaa tatggtcaaa tgattgggga gtcaatggaa ggttatacac
    46621 caggtgaact gccttctatt gatttcttag aagggcgtta tgctaggata gaggctcttt
    46681 cagtggaaaa gcatgcggag gatttgctag ctgtttatgg gcctgatacg cctcaggaga
    46741 tgtggaccta cctttttcag gagccagtag cagatatggg ggagctggtt agccttttac
    46801 atcagatgtt ggctcgtaag gaccgttttt actatgcaat catagacaag gcgactggta
    46861 aggctttggg atctttttct ctcatgcgca ttgaccagaa taaccgagta atagaagtcg
    46921 gagcagtcac tttttctcca gagctaaggg gtacacggat aggaactgaa gctcagtatc
    46981 tcctagctcg ctatgttttt gaggagctaa actatcgtcg ctacgagtgg aaatgcgatg
    47041 ccttaaatct gccatccaga cgagctgcgg agcgtttgag ctttatttat gaaggaacct
    47101 tccgtcaggc agtggtttat aagggacgta cgagagatac ggattggttg tctatgattg
    47161 ataaggactg gcctcaagtc aaagatcgtt tggaaacatg gttgcgtcct gaaaattttg
    47221 ataaaaatgg acagcagtac aagagcttga gagaacttta agaggtgttg agatgattac
    47281 tattaaaaag caagaaattg tcaagctaga ggatgtttta catctctatc aggctgtcgg
    47341 ttggacaaat tatacccatc aaccagagat gctggagcag gccttatctc attcattagt
    47401 aatttatctg gcacttgatg gtgatgctgt ggtgggcttg attcgtttgg ttggagatgg
    47461 attctcatca gtattggttc aggatttaat cgttttacca atctatcagc gtcaaggaat
    47521 tggtagtgcc ttgatgaaag aggctttaga ggattacaaa gatgcctatc aagtccagct
    47581 ggtgacagaa gagacagaaa gaaccttggg cttctatcgt tctatgggct ttgaaatctt
    47641 atccacctat aattgtatag ggatgacttg gatgaatcgt aaaaaataac aaaacttgtt
    47701 ttttcttaag caaaatttaa ggatggtcta gtattatata gtcattaaat aaagacctcc
    47761 taactttatt taataaaatc caaaagtttt tttcatcata atctcctaat gaagtcaccc
    47821 aatcaggtga ctttttgtgg ggtgaggtga tggtaataga aattttttga aaaatggtag
    47881 aatttgagaa aagttaagct agttttaagc tttgtcttgt atcatatagt tattaaataa
    47941 agacctccta actttattta ataaaatcct aaacttttct ttttcataat aatctccctt
    48001 aactccaccc aatcaggtgg agttttttgg ctttatttca ggcttttggg gactattcta
    48061 aaaatcattt ttcgatattt tttggtattt ttcggatttt ggtcggggaa ttggcgggaa
    48121 cttttttaga aaatatgact aagaaatagg tttgttgtta cttcagctac ttcaaactca
    48181 atttgattgt aagtgactgt taattgaagg actgaaactg ctgtaataat gattttgctt
    48241 gtccagtagt ggcgtattaa atgaggagtg acatataaga ttgtctcttc gtttactaaa
    48301 tcaaaatttc tatgaaattg atagaatccc taattttctc ttaaacttga aagtcttgtt
    48361 gtaaagcggt taaagcttga gaagctgagg atgtaaagtt ttgacaaatt ttgtgaactg
    48421 tgggataatg gagaggaatt aaggattagt tctatatcat ggactagaaa agaccccaag
    48481 ctaacttcca cattaagctc ggggtctttt ttgacactat ctatctttgt ttagccattt
    48541 atcgactaag cgaagaacaa caccgaccac aattggtccg atgatagttt taaggattag
    48601 ttccatcatg ggctatctca cctcctttcg taggcggtgt agcagtgccg tagaatatta
    48661 taccacataa gtattaaact cgggaggcac ccaatcaggt ggagtttttt tgctctattt
    48721 caggcttttg gggactattt taaacatcat tttccgataa cttttgctta atcttataaa
    48781 ttttattgga cagattctaa agttggagaa gctgaattga tgaagatata aacctttgac
    48841 aaattttgtg aactatggga taataaaagg gaattaagta ttgtgtctat atcataggct
    48901 agaaaagacc ccaagctcac gaccaaataa gcttggggtc tttttgacac tatttgtcct
    48961 tgtttagcca tttatcgact aatcgaagaa cgacaccgac cacaattggt ccgatgatag
    49021 ttttaagtat tgtatccatc atgggctaat tcacctcctt tcgtaggcgg tgtagaagtg
    49081 ccgaacaata ttataccaca taagtgttaa agtcggaatt cacccaatca ggtggagttt
    49141 tttggctcta ttttaggctt ttggggacta ttctaaaaat catttttcga tatttttcgg
    49201 attttggtcg gggaattggc ggggatgaaa atgtaaaact ttgacaaaat ttgtgaacta
    49261 tgggataata aaaaggaatt gagtactagt tctatatcat ggactagaaa agaccccaag
    49321 ctcacgacca aataagcttg gggtcttttt ttgacactat ttgtccttgt ttagccattt
    49381 atcgactaat cgaagaacga caccgaccac aaatggtccg atgatagttt tgagtactaa
    49441 ttccatcatg ggctatctca cctcctttcg taggcggtgt agcagtgccg tatgatatta
    49501 taccacataa gtgctaaact caggagttac ccaatcgggt ggctttttgt ttgtggcttg
    49561 gatttttgat ataatagagc catgagtaga attttagaca atgagataat aggggacgag
    49621 gagttagtag aacgcacgct ccgtcctcag tacttacgtg aatatattgg gcaggacaag
    49681 gtcaaggacc agctacaaat ctttattgag gctgccaaaa tgcgggatga agcgctggat
    49741 catgtgctct tatttgggcc tccaggcttg ggaaaaacga ccatggcctt tgttattgcc
    49801 aacgaactag gtgtaaatct aaagcagacc tctgggcctg tcattgaaaa agccggtgat
    49861 ctggtagcaa ttttgaatga tttagagcct ggggatgtcc tttttattga tgagattcat
    49921 cgcttgccaa tgtcagtgga agaggtgctt tatagtgcta tggaggactt ctacatagat
    49981 attatgattg gggctggtga gggtagtcgt agtgttcatt tggagttacc accttttacc
    50041 ttgattggtg cgacgactcg ggctggtatg ctctcaaatc cactacgggc acgttttggg
    50101 attacaggcc atatggagta ttatgcccat gctgacttga cagaaattgt cgagcggacg
    50161 gcagatattt ttgagatgga aatcactcat gaggcagcat ctgagttggc cctacgtagt
    50221 cgtgggaccc ctcgtattgc caatcgtctc ctcaagcgcg tgcgcgattt tgcccagata
    50281 atggggaatg gggttatcga tgatgttatt accgataagg ctttgactat gctggatgtt
    50341 gaccacgaag gtttggacta tgtggatcaa aaaatccttc gcaccatgat tgagatgtac
    50401 ggtggtggcc ctgtcggatt aggaactctt tctgtcaata ttgccgagga gcgtgagact
    50461 gtagaagaca tgtatgagcc ttacttgatt caaaaaggtt ttatcatgcg gacacggtct
    50521 ggacggatgg cgactgctaa ggcatatgag catttggggt atgagtacaa tgaaaaataa
    50581 gcaagaaatt ctagagtctt ttagaaaaaa tccagatatg atggctattc tgactatcat
    50641 ccaaaacctg gagttgacag attcctggtt ggcagcaggt tctgtcagaa atttcatctg
    50701 gaatctcttg tcagacaaat caccttttga ctttgaaaca gatgtagatg tgattttctt
    50761 tgatccggat atttcttatg aggaaacctt attactggag aaaaaactgc gagaggactt
    50821 tcctcagtac cagtgggaat tgaaaaatca agtctatatg caccagcaca gccctcatac
    50881 tgctccctat accagttccc gtgatgctat gagtaagtat ccagaacgat gtacggctgt
    50941 tggactgcgc ttgaatgaag aacctgcttt ggaactcttt actccatacg gtctggagga
    51001 tattttgaat tttcaagttc gtccaactcc tcatttttta gagaatcaag aacgaatgga
    51061 actctatcaa acacgtttat ccaagaaaaa ttggcaggag aaatggaaaa atttgatttt
    51121 taaaaatact taaggaaact ttaagctagg gagtgtacac taagttcata agttaagaag
    51181 accttaactt aaactcctaa aactttttca taataatctc cctataaaaa taaagtcgcc
    51241 caatcaggcg gcttattttt ttgaaaaatg ggcttggtgc ctgagaataa atagcttagt
    51301 gatagaagaa aatggggaaa tatggtataa tgaaacgata gatttttgaa taggaataag
    51361 atcatgtttg gattttttaa gaaagataag gctgtggaag tagaggttcc gacacaggtt
    51421 cctgctcata tcggcatcat catggatggc aatggccgtt gggctaaaaa acgtatgcaa
    51481 ccgcgagttt ttggacataa ggcgggcatg gaagcattgc aaaccgtgac caaggcagcc
    51541 aacaaactgg gcgtcaaggt tattacggtc tatgcttttt ctacggaaaa ctggacccgt
    51601 ccagatcagg aagtcaagtt tatcatgaac ttgccagtag agttttatga taattatgtt
    51661 ccggaactac atgcgaataa tgttaagatt caaatgattg gggagacaga ccgcctgcct
    51721 aagcaaacct ttgaagcttt aaccaaggct gaggaattga ctaagaacaa cacaggattg
    51781 attcttaatt ttgctcttaa ctatggtgga cgtgctgaga ttacacaggc gcttaagttg
    51841 atttcccagg atgttttaga tgccaaaatc aacccaggtg acatcacaga ggaattgatt
    51901 ggcaactatc tctttaccca gcatttgcct aaggacttac gagacccaga cttgattatc
    51961 cgtactagtg gagaattacg tttgagcaat ttccttccat ggcagggagc ctatagtgag
    52021 ctttatttta cggacacctt atggcctgat tttgacgaag tggccttgca ggaagctatt
    52081 cttgcctata atcgtcgtca tcgccgattt ggaggagttt aggaggaaat atgacccagg
    52141 atttacagaa aagaaccttg tttgcaggga ttgccctggc tattttccta ccaattttaa
    52201 tgattggggg cctcttgctt cagatagcaa tcggaatcat agccatgcta gccatgcatg
    52261 aacttttgaa gatgagaggt ctagagacca tgacgatgga gggcctcttg accctctttg
    52321 caacctttgc attgaccatt cccttggaga attacctgac ttttttgcca gttgatggga
    52381 atgtggttgc ctatagtgtt ttgatttcaa tcatgttagg aacgaccgtt tttagcaagt
    52441 cttatacgat tgaggatgcg gttttccctc ttgctatgag cttctacgtg ggctttggat
    52501 ttaatgcttt actagatgct cgtgttgcag gtttggacaa ggctctctta gccttgtgta
    52561 tcgtctgggc gacagacagt ggtgcctatc ttgttgggat gaactatggg aaacgaaagt
    52621 tagcaccaag ggtatcgcct aataaaaccc ttgagggtgc cttgggtggt attttaggag
    52681 caattttagt aaccattatc tttatgatag ttgacagtac agttgctctt ccatatggaa
    52741 tttacaagat gtcagtcttt gctattttct ttagcattgc tggacaattt ggtgatttac
    52801 tagaaagttc gatcaaacgt cattttggtg ttaaggattc tgggaaattt atccctggac
    52861 atggtggtgt tttggatcgt ttcgatagta tgttgcttgt atttccaatc atgcacttat
    52921 ttggactctt ttaatcaaaa gacggaggaa acgctatgct cggaatttta acctttattc
    52981 tggttttcgg gattattgta gtggtgcacg agttcgggca cttctacttt gccaagaaat
    53041 cagggatttt agtacgtgaa tttgccatcg gtatgggacc taaaattttt gctcacattg
    53101 gcaaggatgg aacggcctat accattcgaa tcttgcctct gggtggctat gtccgcatgg
    53161 ccggttgggg tgatgataca actgaaatca agacaggaac gcctgttagt ttgacacttg
    53221 ctgatgatgg taaggttaaa cgcatcaatc tctcaggtaa aaaattggat caaacagccc
    53281 tccctatgca ggtgacccag tttgattttg aagacaagct ctttatcaaa ggattggttc
    53341 tggaagaaga aaaaacattt gcagtggatc acgatgcaac ggttgtggaa gcagatggta
    53401 ctgaggttcg gattgcacct ttagatgttc aatatcaaaa tgcgactatc tggggcaaac
    53461 tgattaccaa ttttgcaggt cctatgaaca attttatctt aggtgtcgtt gttttttggg
    53521 ttttaatctt tatgcagggt ggtgtcagag atgttgatac caatcagttc catatcatgc
    53581 cccaaggtgc cttggccaag gtaggagtac cagaaacggc acaaattacc aagattggct
    53641 cacatgaggt tagcaactgg gaaagcttga tccaagctgt ggaaacagaa accaaagata
    53701 agacggcacc gactttggat gtgactattt ctgaaaaggg gagtgacaaa caagtcactg
    53761 ttacacccga agatagtcaa ggtcgttacc ttctaggtgt tcaaccgggg gttaagtcag
    53821 attttctatc catgtttgta ggtggtttta caactgctgc tgactcagct ctccgaattc
    53881 tctcagctct gaaaaatctg attttccaac cagatttgaa caagttgggt ggacctgttg
    53941 ctatctttaa ggcaagtagt gatgctgcta aaaatggaat tgaaaatatc ttgtacttct
    54001 tggcaatgat ttccatcaat attgggattt ttaatcttat tccgattcca gccttggatg
    54061 gtggtaagat tgtgctcaat atcctagaag ccatccgccg caaaccattg aaacaagaaa
    54121 ttgaaaccta tgtcaccttg gccggagtgg tcatcatggt tgtcttgatg attgctgtga
    54181 cttggaatga cattatgcga ctctttttta gataatcgag gaatattatg aaacaaagta
    54241 aaatgcctat cccaacgctt cgcgaaatgc caagcgatgc tcaagttatc agccatgctc
    54301 ttatgttgcg tgctggttat gttcgccaag tttcagcagg tgtttattct tatctaccac
    54361 ttgccaatcg tgtgattgaa aaagctaaaa acatcatgcg ccaagaattc gaaaagattg
    54421 gtgctgttga gatgctggct ccagcccttc ttagtgcaga attgtggcgt gaatcaggtc
    54481 gttacgaaac ctatggtgaa gacctttaca aactaaaaaa ccgtgaaaaa tcagacttta
    54541 tcttaggtcc aactcacgaa gaaaccttta cagctattgt ccgtgattct gttaaatctt
    54601 acaagcaatt gccactcaac ctttatcaaa ttcagcccaa gtatcgtgat gaaaaacgcc
    54661 cacgtaatgg acttcttcgt acacgtgagt ttatcatgaa ggatgcttat agtttccacg
    54721 ctaactatga tagtttggat agtgtttatg atgagtacaa agcagcctat gagcgtattt
    54781 tcactcgtag tggtttagac ttcaaggcta ttattggtga cggtggagcc atgggtggta
    54841 aggatagcca agaatttatg gccattacat ctgctcgtac agaccttgac cgctgggttg
    54901 tcttggacaa gtcagttgcc tcatttgacg aaattcctgc agaagtgcaa gaagaaatca
    54961 aggcagaatt gctcaaatgg atagtctctg gtgaagatac cattgcttac tcaagtgagt
    55021 ctagctatgc agctaactta gaaatggcaa caaacgagta caaaccaagc aaccgtgttg
    55081 tcgctgaaga agaagttact cgcgttgcaa cgccagatgt taaatcaatt gatgaagttg
    55141 cagctttcct caatgttcca gaagaacaaa cgattaaaac cctcttctac attgcagatg
    55201 gtgagcttgt tgcagccctt ctagttggaa atgaccaact caacgaagtc aagttgaaaa
    55261 accacttggg agcagatttc tttgacgttg ctagcgaaga agaagtggcg aatgttgttc
    55321 aagcaggatt tggttcactt ggaccagttg gtttgccaga gaatattaaa attattgcag
    55381 atcgtaaggt gcaagatgtt cgcaatgcag ttgtcggtgc taacgaagat ggctaccact
    55441 tgacgggtgt gaacccaggc cgtgatttta ctgcagaata tgtggatatc cgtgaagttc
    55501 gtgagggtga aatttcccca gatggacaag gtgtccttaa ctttgcgcgt ggtattgaga
    55561 tcggtcatat tttcaaactc ggaactcgct attcagcaag catgggagca gatgtcttgg
    55621 atgaaaatgg tcgtgctgtg ccaatcatca tgggatgtta cggtatcggt gtcagccgtc
    55681 ttctttcagc agtgatggag caacacgctc gcctctttgt taacaaaacg ccaaaaggtg
    55741 aataccgtta cgcttgggga atcaatttcc ctaaagaatt ggcaccattt gatgtgcatt
    55801 tgattactgt caatgtcaag gatgaagaag cgcaagcctt gacagaaaaa cttgaagcaa
    55861 gcttgatggg agctggttat gaagtcttga cagatgaccg taacgaacgt gtcggagtga
    55921 agtttagtga tagcgatttg attgggttac caatccgtat cactgttggg aagaaagcag
    55981 ctgatggcat cgtagaagtt aagattaagg cgactggtga caccattgag gttcatgcag
    56041 ataacgtgct tgaaacgctt gaaatcctaa gcaagaaata aaaactataa tcagaagaaa
    56101 aacaaggaaa aaatgtaact agtttttacc ttgttttttc tgtataatgg gagaaatgag
    56161 tagataaaga ggtaaatgta tgctaagatt tccaaaggat tttgtctggg gctcctctac
    56221 ttctggaccg cagacagaag gacgtgtagc tggtgacggt aagggagaca atctctggga
    56281 ttactggttc caagtggagc caaatcgtta ctataatggg attggttcag ataagacatc
    56341 gactttttat gaaaattggg agcgggatat tgagcttttg ttagagactg gtcacacagc
    56401 ctttcggact tctattcagt ggtcacggat ttttccacaa ggctgtggaa aagtcaaccc
    56461 tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt aaggctaaag gaattcgtct
    56521 gttagtcaat ctctatcatt ttgatttacc ttttgccctt caagaggatg gtgatggttg
    56581 ggaaaataag gcaacagtct tagcctatga agactatgct cgtttttgtt ttgagactta
    56641 tggagattta gtggatcaat ggattacctt taacgagccc atcgttcctg tagaatttgg
    56701 ttatttttat gatgcccatt atccacataa ggtggatgca gaggcagctg ttaaggtagc
    56761 ctatcataca caattggcca gcagtcgggc tgttaaggct tgccatgaac ttttgcctga
    56821 ttccaagatt gggattgtcc tcaacttgac accggcttat ccacgtagcc agcatcctgc
    56881 tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc caatctttct tagatccatc
    56941 tgtcttgggg acttatccac aggagttggt agaaatcttg catgaacacg gtcttttacc
    57001 tgatgctaca gaggaagagt tggaactcat tcgtgataat acggtggact tccttggtgt
    57061 gaactactat caacctttgc gtgttatggc tcctcgattt gctaagcatc cagagagtcc
    57121 actcttacca gaacattttt acgagcctta tgtgatgcct ggacgtaaaa tcaattctca
    57181 tcgtggttgg gagatttatg agcaagggat ttatgacatc gcccaaaata tcaaggaaaa
    57241 ttatggcaat attgagtgga tgttgactga gaatggtatg ggtgttgaag gggaagaaaa
    57301 attccgtcaa gatggaatga ttcaagatga ttaccgtatt gactttgtaa aaggtcatct
    57361 tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt aagggctact tgatttggac
    57421 ctttattgac tgctggtcat ggctcaacag ctataaaaat cgctatggtt tggtcgaatt
    57481 agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc cactggttca aagaattaag
    57541 cgataataat ggattttaaa aaggactctg actgattatc ccaatcggtc agagttttta
    57601 tgcttacagg agcttaattt gaactatacc aatttttact cttgacaagt gaaagaaaca
    57661 agtatatact gtttttgctg attctataaa agatgaatta gactatacca attttaagga
    57721 gaaagcacag cttgcctgtg tcgtatatac tatgtgtgga attgttggtg ttgttggaaa
    57781 cacaaatgca actgatattt tgattcaagg gcttgaaaag cttgaatacc gtggctatga
    57841 ttctgcggga atttttgtcc tagatggtgc tgataaccat ttggtgaagg cggttggtcg
    57901 tattgcagaa ttgtctgcca agacagctgg tgttgaggga acaactggta tcggacatac
    57961 tcgttgggct actcacggaa aaccaactga ggacaatgct cacccacacc gctctgagac
    58021 agaacgtttt gtcttggtgc ataatggggt gattgagaac tatcttgaaa tcaaggaaga
    58081 ataccttgca ggtcaccact tcaaggggca gacagatact gaaatagccg ttcatttgat
    58141 tggaaaattt gcggaagaag aagggctctc agttcttgaa gcctttaaaa aagctcttca
    58201 tattatccgt ggttcatatg cctttgcctt gattgactct gaaaatccag atgtcatcta
    58261 tgtagcgaaa aacaaatctc cacttttgat tggtcttggg gaaggctaca atatggtctg
    58321 ctcagatgct atggctatga ttcgtgaaac caaccaatac atggaaattc atgaccaaga
    58381 gttggtaatc gtcaaggctg atagcgtgga agttcaagac tatgatagta acagtcgtga
    58441 acgtgctagc tatactgcgg aacttgactt gtcagatatc ggtaagggaa cttaccctta
    58501 ctacatgctc aaggaaattg acgagcaacc aacagtgatg cgtaagttga tccaagccta
    58561 cacagatgag gttggtcaag tagtcgtaga ccaagctatc attcaggctg ttcaagacgc
    58621 agaccgcatc tacatccttg cagctgggac atcttaccac gcaggatttg cttctaagaa
    58681 gatgctggaa gaattgacag atacaccagt tgaacttgga atttcatctg agtggggtta
    58741 cggtatgcca cttctcagca agaaaccact cttcatcttt atcagccagt ctggtgaaac
    58801 agcagatagc cgtcaggttt tggtcaaggc taatgaaatg ggaatcccaa gcttgacagt
    58861 gacaaacgtc ccaggttcaa ctctttctcg tgaagccaac cataccatgc tccttcatgc
    58921 aggtcctgaa attgccgtgg catcaaccaa ggcctataca gcgcaaattg cagcccttgc
    58981 cttccttgca aaagcagtcg gagaagcaaa tggcaatgcc aaagcgcaag cctttgattt
    59041 agttcatgag ttgtcaatcg tagctcagtc tatcgaatca actctttcag agaaagaaac
    59101 cattgaagtc aaggttcgtg agctacttga aacaactcgt aacgcctttt acatcggacg
    59161 tggtcaagat tactacgtag ccatggaagc aagtctcaaa cttaaagaga tttcttacat
    59221 ccagtgtgaa ggctttgcgg caggagaact taagcacgga actattgcct tgattgaaga
    59281 aggaacacct gttttgactc tcttgtcaga tccagtcctt gccaaccaca ctcgtggaaa
    59341 tatccaagag gtggcagccc gtggtgcaaa agtcctcact atcgcagaag aaaatgttgc
    59401 taaagagaca gacgctatcg tccttacgac tgtacaccct tacctctcac caatttcaat
    59461 ggtcgtacca acacaattgg tcgcttactt tgcaaccctc caccgtggcc tcgatgtgga
    59521 caaaccacgt aaccttgcca agtcagtaac ggtagaatag aatctatgaa tatacgggcg
    59581 taaagccata ggtttatcct ataaggtttt acagcctatt ttttatgtta caaatgatga
    59641 taagggttta cttttcaata attatagcag attgaattta gaacagtaca caggaatact
    59701 aaaatatttc tagaaattaa tttgaatttt ccaattgatt tgttcgtatc ttatttcaaa
    59761 ctactataaa aagaggaagc tgggcaaaaa ctcaatttga agagaaaatt cagtaaatct
    59821 ttccatgata aaacgcatca tattaaggtt ttgtacacct gatatgatgc gttttatcat
    59881 ttttaagcct ttttgcccag cctcgtcaaa agtaaagttt tggcacaaaa tctgtgacaa
    59941 aactttagtt ttaaaggttt ttaactttgt atatactagt tttaagaaaa ggaggatgat
    60001 cctaatggaa gaaaaagtat cattgaaagt cagagttcaa aaactaggga catcgctttc
    60061 aaatatggtt atgcccaata ttggagcatt tattgcttgg ggagtgttga ctgccctctt
    60121 tatcgctgat ggctatctgc caaatgaaca gttagctact gttgttggtc ctatgttaac
    60181 gtatttattg ccaatcctga ttggttacac aggtggatat atgatccatg gtcaacgtgg
    60241 tgccgttgta ggagctattg ctactgttgg tgcaatcaca ggttctagtg ttcctatgtt
    60301 tatcggagct atggtaatgg gctcactggg aggatggact atcaagaaat ttgatgaaaa
    60361 gttccaggaa aaaattcgtc ccggatttga aatgttagtt aataatttct cagctggtct
    60421 cgttggtttt gcattattgc ttttggcttt ctacgcaatc ggtccagtcg tatcgactct
    60481 tactggagct gttgggaatg gtgttgaggc tattgttaat gctcgcctcc ttcctatagc
    60541 taatattatc atcgaaccgg ctaaagtcct tttcctcaat aatgccctca atcatggcat
    60601 ttttactcct ctgggagtag aacaggtagc tcaagctggt aagtcaattc tcttcctatt
    60661 ggaagctaat cctggaccag gcctgggaat tctattagct tatgctgtat tcggtaaagg
    60721 ttctgctaaa tcttcttctt ggggggcaat gcttattcat ttcttcggag ggattcatga
    60781 aatttacttt ccttatgtta tgatgaagcc tactctattt ttagctgcta tggcaggagg
    60841 tatctctgga acttttactt ttcaactctt agacgctggt cttaaatctc cagcttcacc
    60901 aggttctatt attgcgatta tggctacggc gccaaaaggc gtttggcccc atctaaatgt
    60961 tcttctaggt gttttagtgg cagcagttgt ttctttcctt gtagcagccc ttattcttca
    61021 tgcagacaag tcaactgagg attcgctcga agctgctcag gcggctaccc aagcagctaa
    61081 ggctcagtct aaaggtcagt tagtatcaac ttctgttgat gcagttgttt cgacagactc
    61141 agtggaaaaa atcattttcg cctgcgatgc tggtatggga agctctgcta tgggagctag
    61201 tattcttcga gataaggtta aaaaagcagg tctagagatt ccagtatcta atcaggcaat
    61261 ctcaaatttg cttgatacac caaaaacatt aattgttact caggaagaac tgacaccaag
    61321 agctaaagac aagagtccaa gtgctattca tgtttctgtt gataatttct tagcgtcccc
    61381 tcgttatgat gaaattgtag cttcattaac aggagcttct ccaatagcag aaattgaagg
    61441 agatatatca acttcagcat cagtagatag tcaggaaatt gactttaacc atattgatgc
    61501 tgtagtagtt gcttatggta aagcacaggg atctgcaact atgggctgtg aaacgattcg
    61561 ggctatcttt agaaacaaga atattcgtat tccagtttct actgccaaaa tttcagaatt
    61621 aggtgaattt aattctaaaa acataatgat tgtaacaact atttctttac aggcagaagt
    61681 gcagcaaaca gcaccgaatt ctcaatttct tattgtggat agtttagtaa caacaccaga
    61741 atatgacaaa atggctgtta gaatgtacaa atagaactag aggtttctaa attacgaatg
    61801 ctattaacca aacgagaaga acaattattg aaggctttcc tacatgtagg gaagctttca
    61861 atgcaagaca tgactgaaat cttacaggtt tcatctagaa caatttatcg aactttatca
    61921 gatttgacag atagcatgga gcaatatgga atcgaaataa cgaagcatgg gaaatactat
    61981 attttgactg gagagttgga tgatttgccg acagaacttg aagtgttagt tgagtatagt
    62041 ccccaagaaa gacaagagtt gattacctat cgccttctga ctgagagtgg ttttgtcacc
    62101 aatgaagcat tgcaagagtg catgaaagtc agtaatgtaa ctattattca ggatatttca
    62161 gatattgata agcgtctttt agactttgat ctgaaaattg aacgacaaaa aggttatcgt
    62221 atttctggtg attcagttgg taagagaaga tttttggcta ttttactgac aaactgtatc
    62281 tcagtagcag atttttcaac cggtaatttt gggagctttg atattttaga agcagataga
    62341 actaggctgg ccagtcagat tgttaataag caactgtcag gttttccaga tatggatgct
    62401 aggatgaaga tgttttttgc gatcttgtta tctcttatag gtcaggagca aaacattgaa
    62461 aattcaccta atactagtaa gcaggctttg gaaatttctc aaaaaatttt tcaagcttac
    62521 tctaagcaga ctgcacaatt ttatagtatt caggaaatta tctattttgc gagcatctta
    62581 gatgaattaa tcattaaacg tcaggacaat ccgctcttta cggagaaatt tgatggtgaa
    62641 tttttctaca atatttcaaa tctgattgat acggtttcca tgtataccaa gattgacttt
    62701 tttaaggaca aggttttatt caattttctt ttccatcata ttcggctcag tttaggcgtc
    62761 cctatccttt ttcagggtga aaatttgcca gaatctgtcc agattttagt tgaaaggaat
    62821 aaatttcttt atacagtcat cagtctttta gtgaatgata tttttccgaa atatcttcat
    62881 acagagtatg agtatggcat gattgcccta cattttatct ctagcttagg ccgtagtcca
    62941 gagatttatc cagtccgtgt tttgctttta acggatgaac gtcgggtcac tagagattta
    63001 ttagtcagta aaattaagag tgttgctcct tttgtagagt tgatagatat tcagtctcta
    63061 gtagattacc acagtattga tctcagtcag tatgattata ttttatctac caagccgctg
    63121 actaatcagg aaatcgatgt aatttctagt tttccaaccg tcaaagaact gcttgaatta
    63181 caggaacgac ttcagtatgt acaggcacat cgtacaattg tcgcgcgtga tgctatcgct
    63241 ccagagaaaa gttatgactt gcaagattat ttaatatcta gtagtcagct tttgagtcaa
    63301 ttcgagttgg ttcaattgga gaataatcaa tcatttgagc acacggtaga acaaatcatc
    63361 caatatcaga agaatgtgag tgacagagat tacctaacaa gaaaattgtt atctcacttc
    63421 cagaatagtc ctatggctat tcctaatact ggtctggtgc ttttacatag tcagtctagc
    63481 aaagtaacaa caaatagttt tactatgttt gaactcaaac tacctatctc cgcattgtca
    63541 atgaaacgag aggaagaaga ggtcaaaagg tgtctgctaa tgctaatgtc taaagaagct
    63601 agcgaggaag cgagagattt aatgacagct attagtcagt cgattattga aaatcatctt
    63661 tatacagaga tttacaagac gggaaatcaa tccattattt atcagatgct aaatactatt
    63721 tttaacgaaa aaattaagaa attggagaac taatatgaaa cttgaaaaac atttgattaa
    63781 gcttaataaa caattttcta acaaggagga agctatttgt tattgtgggc aagttcttta
    63841 tgagggtgga tatgttaatg aagactatat tgaagccatg attgagcgag ataaagagct
    63901 atctgtttac atgggtaact ttatcgccat accgcatgga acagatgcag caaaaaagga
    63961 tgtcctcaag tctggtatta cagtcgttca agtccctaga ggggttgatt ttgggaatgt
    64021 atctaaccct caagtggcaa cggttctttt tggtattgct ggtattggta atgaacactt
    64081 agaaattatt cagaaaattt ctatcttctg tgcagatgta gataatgttc ttaaactagc
    64141 agatgctcag tcaaaagagg aagtattgcg cttatttgat gctgttgaat aattgaattt
    64201 cgtcatttgt catctagtat atatgtccct caaataggaa aaggagaaat tgaatgaaac
    64261 attctgttca ttttggtgcc ggtaatatcg gtcgtggttt tataggtgaa attctattta
    64321 aaagtggttt ccatattgat tttgtggatg tcaataatca gataattcat gctctaaatg
    64381 aaaagggcaa gtatgaaatt gaaattgcac agaaaggaca gtctcgtata gaagtaacta
    64441 atgtggctgg cattaatagc aaagaacatc ctgagcaagt cattgaagcg attcaaaaga
    64501 cggatattat tactactgca atcggaccta atatactccc ttttatcgcc gaacttctag
    64561 ccaaaggaat cgaagctcgc cgagttgcag gaaatacaca ggcattggat gttatggcct
    64621 gtgaaaatat gattggcggg tctcaatttc tttatcaaga agtcaagaaa tatttaagtc
    64681 cggaaggttt gacatttgct gataactaca taggttttcc aaatgctgca gtagacagga
    64741 ttgttccagc acaaagtcac gaagattccc tttttgttgt ggtcgaaccc tttaatgaat
    64801 gggtcgtgga aaccaagcgt cttaaaaatc cagatttacg tctaaaagat gtgcattatg
    64861 aagaagattt agaacccttt attgagcgaa aacttttttc agtcaattct ggacatgcaa
    64921 cttcagctta cattggtgcg cattatggtg ccaagacaat tttggaagct cttcaaaatc
    64981 ctaatatcaa atctcggatt gaatctgtat tagctgaaat tcggagtctc ttgattacca
    65041 aatggaactt tgataaaaaa gaattggaga attatcacaa agtcattata gaacggtttg
    65101 aaaatccttt catagtggac gaggttagtc gcgtagctcg tactccaatc cgaaaattag
    65161 gctataatga acgattcatc cggccgatac gtgaattgaa agaactcagt ttgtcatata
    65221 aaaacctact taaaacagtt ggctatgcct ttgactatcg cgatgtaaat gatgaagaaa
    65281 gtattcgatt aggtgaattg ttggctaaac aatcagtcaa agatgttgtt atacaagtta
    65341 caggtttaga cgacccagaa ttgattgagc aaattgtaga gtatatttaa tctttttcga
    65401 aaatctcttc aaatcaggtt agcatccatc tgcaacctca aaacagtatt ttgagctgac
    65461 ttcatcagtt ctatctacca cctcaaagca gtgctttgag ctgactccgt cagtcttatc
    65521 tgcaacctca aaacagtgct ttgagcgcct gcggctagct tcctagtttg ctctttgatt
    65581 ttcattgagt gttagaataa tttttcaaat tgaaggacag agatagacaa ggagaatcac
    65641 aatggtagaa ttgggaattt caacatttgg ggaaataacg gagcttgaag ggactggaca
    65701 aacttacagt catgctgaac gcattcgcca gttggtggca gagattgagc tggctgacaa
    65761 ggttggtttg gacgtatatg ggattggcga gcaccatcgg gcggattttg cagtatcagt
    65821 cccagagatt gtcctggccg ctggggcagt caatatcaag aaaatccgtt tgaccagtgc
    65881 agtcagcatt ctgtcaagca tggctctgat tcgtttgttc caacagtatg ccactatcga
    65941 tgctttgtca aatggacgat cggagattat ggctggaagg ggctctttca cggaatcttt
    66001 ccctctgttt ggttatgact tgaaagacta cgactctctt tttgatgaga aattagactt
    66061 gcttcagtta gtcaatgaaa agaccaagtt agactggcaa ggtcgattga ctcaaacgat
    66121 tgctggtaaa gaagtttatc ctcgtccagt ttaggacaaa ttgcccttgt ggatagctac
    66181 aggtggtcat gtcgaatcaa cagtgaagat tgctcaggct ggtctaccga ttgtatatgc
    66241 tattattggt ggtaatccac gttattttaa aaagttgatt caggcttatc gtgagattgg
    66301 aagcgaagcg ggccatgctg acaaagactt gaaagtggga gcccattctt gggggtggat
    66361 tgcggaagat ggtgagcagg cggtgaaaga ttatttccat ccgactaagc aagtggtgga
    66421 tgctatttcc aaagaccgtc cgcactggca ggaattgcgt tatgagcaat atttggagca
    66481 ggtagggcca aatggcgcca tgtttgttgg caatccagat caggtggcca aaaaattgat
    66541 tcgcatgata gaggatttag gattggaccg cttcatgctt catctaccgc ttggttctat
    66601 gcctcatgac caggttctga gagctattga actcttcgga acacaagttg cacccaaagt
    66661 acgagcttat tttgctatga aagaggctta ataaaaaatc ctaatcaagt ttattaggac
    66721 aacaaatatt gtacaaaaat taatcccccg agctataatg cttgggggat ttttctatag
    66781 gagggctagt ttagttctct tttttatttt ttagtaagaa accgagacca aggagcgcaa
    66841 ggaggctgat tcctgcaaat aggagtttgt tttcgttttt gattcctgta tttggaagtt
    66901 cagcttgttt atctggggtt gcaggtatat tttccttgct agagttttct accgattcgt
    66961 ttcgaaccgc ttcttttaca gatgatgctt gtgcttcttg tgctggttgt tcagcttgtg
    67021 aatcagctgt agcttggcta ggtttatttt ccgcatcagc tactttggca tctggtttag
    67081 tagaatcagg tctagcttct ggagctggat cttgatgttc aggcttggaa ggggttgagt
    67141 ctggtttctc ttctgcagtt gactcatggc tagttccgtt ttgagagact cgaagaacag
    67201 tagctgtaag ggcattcaat ttcaagcctt tttcagtcca ttcaagtcct ttcgggttgg
    67261 caattccgac tggtcctgct tggttttcat ctgccaaaac ttccgcattt cttagatgtg
    67321 caaaggcagt tcccaaatta aattcgcgag ctttttcatc cgcattgaca aagactgcgt
    67381 agatatcgcc gtttggagca gtgatttggt agccaatcac tacatcctct ttttccacac
    67441 cattttggcc tgggacagtg atgaggtgga cacggtcttt gatatcttga agactcttaa
    67501 gtcggaaggc atctgtagat tgacgaaggg caatcaaacc tttcatatag tcacggctct
    67561 tgacattttc aggataagct ttaccatctg tagccttagt ccagtcaaac ttgttgactg
    67621 catcgctaga atcgtaagaa tcatggatga agtaaggata gtcaaatggg ttgccgtcct
    67681 tatcacgcaa caagtgagat ttgtttggaa ccttatcctc tgctactgga gtcttgtagg
    67741 ctgggtcacg gaattgttta gtacgtccat attcctgacc ggagtggata aatggagttc
    67801 cttgagctgt caagaccatg agatttccaa gtcgtaaacg acggtggact tcagcatagt
    67861 tctcagcctt gcttgggtct tttttgatag actgggcaat gatgtcaaag agggtcaagt
    67921 tatcatgggc tgcgatgtat tggatgacat ctccagggct gtcagcttca aagttagttg
    67981 gttgagcaat gagattttta aagatggtgt tgacatcacg cttgccacct gtgataaagg
    68041 caggttgacc ttcgtttgga taaccagatt tgaggttgtt acggatgtca tctgaaaaga
    68101 cagcgacagt atcggtatgt ttcatccaat cttggtcagc agctttagta ggcatgtttt
    68161 catcaccggc ataggttctc caaccttcac caagcatgat gaggtttgga ttgagggcgc
    68221 gtgcagcctt gtaagcttct tcgatagaag tggcgtcatg gtctcccatc atatcgaagc
    68281 ggaagccatc cactttgtag gtatccacta ggtatttgat agagtcaact aggagccgtt
    68341 tggtcatatg gtgggttgtc cccaagcgtc caccaccaaa gctagttcga ggtgtgccat
    68401 cggcatccat aaagtggtag tagtttggct ctaggtcttc aaagatatcg actttggctg
    68461 tgtggttata aacgacatct aggatagctc ccataccacg tttgtggatt tcgttgatga
    68521 ggtttttaaa ttctgcgatt cgtttttctg gattcttagg atcgcttgag tacataccag
    68581 tcaatgagaa gtagttttga gggtcatatc cccagttgta gttgctgttg cttgaagcat
    68641 agtcagacaa gcgttcatgg tttttcaatt cattgacaaa gtagtaagac aagactggaa
    68701 ggagctggat gtgggttaca cccaagtctt tgaggtagtc tagtttttcg ataaaggctt
    68761 caaaagtccc aaatggtttg gtcaagtctt ttgcaatggc aggatctgaa gtgaaatcac
    68821 gcacatgagc ttcgtagata acggcgtctt cacgagtctt gaaattgtga atcttaccat
    68881 aagtcaagtc ttgaggtccg agtttagctg gatctacaaa ggcggcttta gccactttat
    68941 gggcatcgtc aatcttggca tcgtcgctat tccaagcagc aagagattta gcgtaaggat
    69001 cgagtgcaag aacagtttta ccttgacgct cgatttggta ttgataatag tagccagtga
    69061 aatctgtgat tccgagtttg tttgtgctgt ctagagtttg tttccaagtt cctctttccc
    69121 ctttttcgag agcgacagtt ccaactactt tgtcagggtc attcttgtcg tagacaacaa
    69181 cagaaacctt atcagcactt ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt
    69241 ttaggtcagc tcccagtttg ccatcatagc tgtatgtctc atctttcagg cgccagcttg
    69301 ttttggtagt gaattggtcg gaattgtagc taacagtata aggatgtttt gtgtcagaga
    69361 aatctccgct gtaggtcact ttcttaccag cttcatcgat tgcaacatcg gtaatagtta
    69421 ccttgtttcc taggtgatta gtgatgttgg agtgtttgag gatatcttct tttttagcac
    69481 cgacaagtgt tgaaaagcta ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca
    69541 tacggatatc atggacatag tatggatttg tgtaaatcga ttcatcatcg tcttttagga
    69601 aaatttggct atgatttttc aaatctgtga acttataatt ttctttacgg attttcacgt
    69661 cgtctccttg tttgctctca tctagtaata aaaatccaaa ttctcttgcg gcttcattaa
    69721 gaggaatgtc gatatagcgg ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc
    69781 attgagcgct acttggattt ttcacatctc cccagtacca gagagatttc ttgtcatagt
    69841 tgccatctgt gcggtagtag ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga
    69901 aaaccttgta atcttggtct aaccaagcct cgttcatttt tggaactagt ttttctacag
    69961 atttatcgcc ggttagattt tttccagctg tattgttgat gaggaagcta attttcttgg
    70021 cttgttctcc ctttaatttg acatctaggt aatagccgta gtcatctttc ttggcatcct
    70081 tgaaggacaa agctccgttt ggccagtttt cagatggttt ttcaacatcg tcccaagtcc
    70141 atagtccttg agcatccttg ttttcttcag gaagtttttt gacatggata cggaagtagt
    70201 tatcttcgat gggctcttct gccttagttt cagttgttac tggactagta gaagtagttg
    70261 gctctgttgc aggtttttct tctgttttct ctagggaagc gtttgcattt ctaggtgaag
    70321 aaatatcact ttcgttctta ccagagccag ctgctgtatc agtaagaggt tgggcaaggg
    70381 tggttgtatt tctgttgttg ggttcgttag tggttggtgt actttcgtcg gatgagatag
    70441 ttggtgtagc catggcaagc aagacaaggc ttgcgccgat aaggacagaa ccagttccat
    70501 ttttgaggga acggatgctg tagaccattt ttttctcagt gtgagatggt gtttttctca
    70561 taatgattct ccaatcaata aatttctata tcagtatagc atgtagtaaa acaatatgca
    70621 agcgttttct ttgatttgtg aaaaaaattc ttacttttga gaagttttct gtactatttt
    70681 aaccccaatt attcacccca aatctaaaaa ccatccagaa tccttgcctt agcttagatc
    70741 ctggatggtt tcttttttca cccaatgggt gttttttact agacaaaaaa gagtttcccc
    70801 tttatggtat aagtgtagaa aaaaacacaa aaagaaagga aactcacatg aacagtttac
    70861 caaatcatca cttccaaaac aagtcttttt atcaactatc tttcgatgga ggtcatttaa
    70921 cccagtatgg tggtcttatc ttttttcagg aacttttttc ccagttgaaa ctaaaagagc
    70981 ggatttctaa gtatttagta acgaatgacc aacgccgcta ctgtcgttat tcggattcag
    71041 atatccttgt ccagttcctc tttcaactgt taacaggcta tggaacggac tatgcttgta
    71101 aagaattgtc agctgatgcc tactttccaa aattgttgga aggagggcag cttgcttcac
    71161 agccaacctt atcccgtttt ctttccagaa ctgacgagga aacagtccat agtttgcgat
    71221 gcctcaacct tgaattggtc gaattctttt tacagtttca ccagctaaac caactcattg
    71281 tagatatcga ttctacccat ttcacaactt atggcaagca agaaggtgtt gcttataacg
    71341 cccactatcg tgctcatggc tatcatcctc tttatgcttt cgaggggaag acaggttatt
    71401 gtttcaatgc ccagcttcgt cctggtaatc gttattgttc tgaagaggca gacagcttta
    71461 tcacacctgt tttagaacgg tttaatcaac ttctctttcg aatggatagt ggctttgcga
    71521 ccccaaaatt atacgattta attgaaaaaa cagggcaata ctacctcata aaactcaaga
    71581 aaaatactgt tctgagccgt cttggagacc tttccctccc ttgcccacag gatgaggact
    71641 taaccatctt gccccactcc gcctactcag aaactctcta tcaagcagga tcttggtcgc
    71701 acaagcgtcg tgtctgccag ttctctgaac gaaaagaagg aaacttgttc tacgatgtta
    71761 tttctctcgt tgcaaatatg acgagtggaa caagccaaga ccagtttcag ctttatcgtg
    71821 gacgtggtca agccgagaat ttcatcaagg agatgaagga gggatttttt ggcgataaaa
    71881 cggatagttc aaccttaatc aaaaacgaag ttcgtatgat gatgagctgt atcgcctaca
    71941 atctctatct ttttctcaaa catctagctg gaggcgactt ccaaacttta acaatcaaac
    72001 gcttccgcca tctttttctt cacgtggtag gaaaatgtgt tcgaacagga cgcaagcagc
    72061 tcctcaaatt gtctagtctc tatgcctatt ccgaattgtt ttcagcactt tattctagga
    72121 ttagaaaagt caacctgaat cttcctgttc cttatgaacc acctggaaga aaagcgtcgt
    72181 taatgatgca ttaaagaaca gtcgagatga aaaaatcgtg tgacgcacca agggaggagt
    72241 ctgccctttt gaggaaatct agcgaggaaa aacgatactg gaacagcaga aagtaaaact
    72301 gacctcatga ggaggaagaa agtggctcat gaggtcaggg gttttgtaag ttacatctag
    72361 ttgagagagg tatgaatgat ttgggtttat atatcagtat aaatgacgga gataaaaatg
    72421 tcacataagc caagccgtat tattaggaag atgatgtgtt cccagctatt tttattcaga
    72481 aattgatctc taacattacc aataaaaaag aaaaatatct tgacaagcaa gggaaaattt
    72541 tgttacaata atagacggta ctttttactt ttggtctctc aagagtgtac agggacgtgc
    72601 tgacaaatgt tgcaaaagta cacacagatg atatctgtca ccaagtgtat catcaccaaa
    72661 aataaaaaaa cacaggagaa tgtagatgcc tacaattaac caattggttc gcaaaccgcg
    72721 taaatcaaaa gtagaaaaat ctaaatcacc agctttgaac gttggttaca atagtcataa
    72781 aaaagttcaa acaaacgttt cttcaccaca aaaacgtggt gttgcaactc gtgttggaac
    72841 aatgacacct aaaaaaccta actcagccct tcgtaaattc gctcgtgtac gtttgagcaa
    72901 ccttatcgaa gttactgcct acatcccagg tatcggacac aacttgcaag agcacagcgt
    72961 ggtgcttctt cgcggtggac gtgtaaaaga ccttccaggg gtacgttacc atatcgtccg
    73021 tggtgcactt gatactgcag gtgttaacga tcgtaaacaa ggccgttcta aatacggtac
    73081 taaacgtcca aaagcataag gaaaggggat aaagagaaat gagtcgtaaa aatagagctc
    73141 caaaacgtga cgtattgcca gatccgctat acaattcaca actagttact cgtcttatca
    73201 accgcgttat gcttgatggt aaacgtggta ctgctgcttc aatcgtttac ggtgcttttg
    73261 agcaaatcaa agaagctact ggcaacgatg cacttgaagt atttgaaaca gctatggaaa
    73321 acatcatgcc tgtacttgaa gtacgtgcac gtcgtgttgg tggttctaac taccaagtcc
    73381 cagttgaagt tcgtccagaa cgtcgtacaa cacttggact tcgttggttg gtaacaatcg
    73441 ctcgtcttcg tggtgaacac acaatgcaag accgtcttgc aaaagaaatc ttggatgctg
    73501 ctaacaacac tggtgcagct gttaagaaac gtgaagatac tcaccgtatg gctgaagcta
    73561 accgtgcatt cgcacacttc cgttggtaag ataggatgcg aaagcgttaa gaaagtccca
    73621 gagaaaatag ggaatcgaag caggttgcgg ttgcaaccaa tgagattcat ctttttctcc
    73681 agacttttag cttgagctca actaaatcat gatgctaggc acggtaagga tgcaaggtga
    73741 aaataggaaa ctgacgcagt attcaacgaa tacaaggagt tttatctttt tcacgcagca
    73801 tcccgttcca gctcacatcg gctaactaac tttagcccgg gttcaaatta gctaaatcga
    73861 ttagtattag ctataactca gcttaccatc tagtaagttg aaaccaacaa tagcatgaaa
    73921 acattgagaa cgggtaggtc ctgcctatcc gtttttatta aaatcgtgtt ataatagaat
    73981 agaaatcaaa aataaatagg agaaacaaac ctcatggcac gcgaattttc acttgaaaaa
    74041 actcgtaata tcggtatcat ggctcacgtc gatgccggta aaacaacaac tactgagcgt
    74101 attctttact acactggtaa aatccacaaa atcggtgaaa ctcacgaagg tgcgtcacaa
    74161 atggactgga tggagcaaga gcaagaacgt ggtatcacga tcacatctgc tgcgacaaca
    74221 gctcaatgga acaaccaccg cgtaaacatc atcgacacac caggacacgt ggacttcaca
    74281 atcgaagtac aacgttctct tcgtgtattg gatggtgcgg ttaccgttct tgactcacaa
    74341 tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag caactgagta cggagttcca
    74401 cgtatcgtat ttgccaacaa aatggacaaa atcggtgctg acttccttta ctctgtaagc
    74461 acacttcacg atcgtcttca agcaaatgca cacccaatcc aattgccaat cggttctgaa
    74521 gatgacttcc gtggtatcat tgacttgatc aagatgaaag ctgaaatcta tactaacgac
    74581 cttggtacgg atatccttga agaagacatc ccagctgaat accttgacca agctcaagaa
    74641 taccgtgaaa aattgattga agcagttgct gaaactgacg aagaattgat gatgaaatac
    74701 ctcgaaggtg aagaaatcac taacgaagaa ttgaaagctg gtatccgtaa agcgactatc
    74761 aacgttgaat tctttccagt attgtgtggt tcagccttca aaaacaaagg tgttcaattg
    74821 atgcttgatg cggttatcga ctaccttcca agcccacttg acatcccagc aatcaaaggt
    74881 attaacccag atacagacgc tgaagaaact cgtccagcat ctgacgaaga gccatttgca
    74941 gctcttgcct tcaagatcat gactgaccca ttcgtaggtc gtttgacatt cttccgtgtt
    75001 tactcaggtg ttcttcaatc aggttcatac gtattgaata cttctaaagg taaacgtgaa
    75061 cgtatcggac gtatccttca aatgcacgct aacagccgtc aagaaatcga cactgtttac
    75121 tcaggtgata tcgctgctgc cgttggtttg aaagatacta caactggtga ctcattgaca
    75181 gatgaaaaat ctaaaatcat ccttgagtca atcaacgttc cagaaccagt tatccaattg
    75241 atggttgagc caaaatctaa agctgaccaa gacaagatgg gtatcgccct tcaaaaattg
    75301 gctgaagaag atccaacatt ccgcgttgaa acaaacgttg aaactggtga aacagttatc
    75361 tcaggtatgg gtgaacttca ccttgacgtc cttgttgatc gtatgcgtcg tgagttcaaa
    75421 gttgaagcga acgtaggtgc gcctcaagta tcttaccgtg aaacattccg cgcttctact
    75481 caagcacgtg gattcttcaa acgtcagtct ggtggtaaag gtcaattcgg tgatgtgtgg
    75541 attgaattta ctccaaacga agaaggtaaa ggattcgaat tcgaaaacgc aatcgtcggt
    75601 ggtgtggttc ctcgtgaatt tatcccagcg gttgaaaaag gtttggtaga atctatggct
    75661 aacggtgttc ttgcaggtta cccaatggtt gacgttaaag ctaagcttta tgatggttca
    75721 tatcacgatg tcgactcatc tgaaactgcc ttcaagattg cggcttcact ttcccttaaa
    75781 gaagctgcta aatcagcaca accagctatc cttgaaccaa tgatgcttgt aacaatcact
    75841 gttccagaag aaaaccttgg tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgta
    75901 gatggtatgg aagcacacgg taacagccaa atcgttcgtg cttacgttcc acttgctgaa
    75961 atgttcggtt acgcaacagt tcttcgttct gcatctcaag gacgtggtac attcatgatg
    76021 gtatttgacc actacgaaga tgtacctaag tcagtacaag aagaaattat taagaaaaat
    76081 aaaggtgaag actaatccgt cctcactcta gaaggaagtc acttagtggc ttccttttgt
    76141 ctttagaaaa tacctctaaa tatggtaaaa tagtagaaga ataatgtgag gaaaatgaat
    76201 gtcaaatagt tttgaaattt tgatgaatca attggggatg cctgctgaaa tgagacaggc
    76261 tcctgcttta gcacaggcca atattgagcg agttgtggtt cataaaatta gtaaggtatg
    76321 ggagtttcat ttcgtatttt ctaatatttt accgattgaa atctttttag aattaaagaa
    76381 aggtttgagc gaagaatttt ctaagacagg caataaagct gtttttgaaa ttaaggctcg
    76441 gtctcaagaa ttttcaaatc agctcttgca gtcctactat agggaggctt tctctgaagg
    76501 tccatgtgct agtcaaggtt ttaagtccct ttatcaaaat ttgcaagttc gtgctgaggg
    76561 taatcagcta tttattgaag gatctgaggc gattgataag gaacatttta agaagaatca
    76621 tcttcctaat ttagccaaac aacttgaaaa gtttggtttt ccaactttta actgtcaagt
    76681 cgagaagaat gatgtcctga cccaagagca ggaagaggcc tttcatgctg aaaatgagca
    76741 gattgttcaa gctgccaatg aggaagcgct ccgtgctatg gaacaactgg agcagatggc
    76801 acctcctcca gcggaagaga aaccagtctt tgattttcaa gcgaaaaaag ctgcagctaa
    76861 acccaagctg gataaggcgg agattactcc tatgatcgaa gtgacgacag aggaaaatcg
    76921 tctggtattt gaaggggttg tttttgatgt ggagcaaaaa gtgactagaa caggtcgtgt
    76981 tttaatcaac tttaaaatga cggactatac ttcaagtttt tctatgcaaa agtgggttaa
    77041 aaacgaggaa gaggcccaga agtttgacct catcaagaag aattcttggc tccgagttcg
    77101 agggaatgtg gagatgaata acttcacacg cgatttgact atgaacgtac aggatctgca
    77161 ggaagttgtt cactatgagc ggaaggattt gatgccagaa ggtgagcgtc gggttgagtt
    77221 tcatgctcat actaacatgt cgactatgga tgctttgcca gaggtcgaag agattgttgc
    77281 aacagctgct aagtggggac acaaggcggt tgctatcacg gaccatggga atgtccagtc
    77341 ctttccacat ggctataagg cggctaagaa agcgggaatc cagctgatct atggaatgga
    77401 agccaatatc gtggaggacc gtgtccctat cgtctataac gaagtggaga tggacttgtc
    77461 agaagcaacc tacgtggtct ttgacgtgga aacgacggga ctttcagcta tctataatga
    77521 cttgattcag gttgcggcct ctaagatgta caaggggaat gttattgctg aatttgatga
    77581 atttatcaat cctgggcatc ccttgtcagc ttttactaca gagttaactg gaattacaga
    77641 tgatcatgtc aaaaatgcca aaccactaga acaagttttg caagaattcc aagaattttg
    77701 caaggatacg gtcctagttg cccacaatgc tacctttgac gttggcttta tgaatgctaa
    77761 ttatgagcgt catgatcttc caaagattag tcagccagtt attgatacgc tggagtttgc
    77821 tagaaacctc tatcctgagt ataaacgcca tggtttgggg cctttgacca agcgttttgg
    77881 tgtggccttg gaacatcacc acatggccaa ctacgatgcg gaagcgactg gtcgtctgct
    77941 tttcatcttt atcaaagagg tagcagaaaa acatggtgtg accgatttag ctagactcaa
    78001 cattgatcta atcagtccag attcttacaa aaaagctcgg atcaagcatg cgaccatcta
    78061 tgtcaagaat caggtaggtc taaaaaatat ctttaagctg gtttccttgt ctaataccaa
    78121 gtattttgaa ggagtgccac ggattccgag aacggttcta gatgcccatc gagagggctt
    78181 gattttaggt tcagcctgtt cagagggtga agtttttgac gtggtcgttt ctcaaggtgt
    78241 ggatggggcg gttgaggtgg ccaagtatta tgactttatc gaggtcatgc caccggctat
    78301 ctatgcgccc ttgattgcca aagagcaggt caaggatatg gaggaactcc agaccattat
    78361 caagagtttg atagaggttg gagatcgcct tggcaagcct gttctggcta cgggaaatgt
    78421 tcactatatc gaaccggaag aagagattta tcgtgaaatt attgtccgta gtttgggaca
    78481 gggtgcgatg attaatcgaa ctatcggtca tggtgaacat gcccaaccag caccacttcc
    78541 aaaggctcat tttcgaacga ctaatgagat gttggatgaa tttgcctttt tgggagagga
    78601 actggctcgt aaactggtta ttgaaaacac taatgccttg gcagaaatat ttgaacccgt
    78661 tgaagtcgtt aagggtgact tgtatacgcc tttcatcgac aaggctgaag aaacagttgc
    78721 tgagttgacc tataagaaag cttttgagat ttatggaaat ccgctgccag atattgttga
    78781 tttgcggatt gaaaaagaat taacatccat actggggaat ggatttgctg tgatttatct
    78841 ggcatcgcag atgctggtgc aacgttctaa tgaacggggt tatttggttg gttctcgtgg
    78901 gtctgtcgga tctagtttcg ttgcgaccat gattgggatt acggaggtca atcctctctc
    78961 tcctcactat gtctgtggtc agtgtcagta cagtgagttt atcacagatg gttcgtacgg
    79021 ttcaggattt gatatgcccc ataaggactg tccaaactgt ggtcacaaac tcagtaaaaa
    79081 cggacaggat attccgtttg agaccttcct tggctttgat ggggataagg ttcctgatat
    79141 tgacttgaac ttctcgggag aagatcagcc tagcgcccac ttggatgtgc gtgatatctt
    79201 tggtgaagaa tatgccttcc gtgcgggaac ggttggtacg gtagctgcca agactgccta
    79261 tggatttgtc aagggttacg agcgagatta tggcaagttt tatcgtgatg cagaagtaga
    79321 acgcctcgct caaggagcgg cgggtgtcaa gcggacaaca ggccaacacc cggggggaat
    79381 cgttgttatt ccgaactaca tggatgtcta cgattttacg cctgtccagt atccagcaga
    79441 tgatgtcacg gctgaatggc agaccactca ctttaacttc cacgatatcg atgagaacgt
    79501 cctcaaactc gatgtactgg gacatgatga tccgaccatg attcgaaaac ttcaggattt
    79561 gtctggtatt gaccctaatg aaattcctat ggatgacgaa ggcgtgatgg cactcttttc
    79621 tgggactgat gtgctagggg taacacctga acaaattgga acgcctacgg gtatgttggg
    79681 gattccagag tttggaacaa atttcgtacg tggaatggta gacgaaaccc atccgacaac
    79741 ctttgcggaa ttgcttcagc tgtctggtct gtcccacggt actgacgttt ggttggggaa
    79801 tgctcaggat ctgattaagc aaggaatagc ggacctatcg actgttatcg gttgtcggga
    79861 cgacatcatg gtttacctca tgcatgcggg tctggaacct aagatggcct ttaccattat
    79921 ggaacgggta cgtaagggtt tgtggctaaa gatttcagaa gaggagagaa atgactatat
    79981 cgaagccatg aaggccaata aggtgccaga gtggtatatc gaatcctgtg ggaaaattaa
    80041 gtacatgttc cctaaggccc atgcggcagc ctacgttatg atggccttgc gtgtagctta
    80101 cttcaaggtt caccatccta tttattacta ctgtgcttac ttctccattc gtgctaaggc
    80161 ttttgatatc aagaccatgg gtgcgggctt ggaggtcatc aagcgcagaa tggaagaaat
    80221 ctctgaaaaa cggaagaaca atgaagcctc taatgtggaa atcgatctct atacaactct
    80281 tgagattgtc aatgagatgt gggaacgagg tttcaagttt ggtaaattag atctctaccg
    80341 tagtcaggcg acagagttcc tcatcgacgg ggataccctt atcccaccat ttgtagcaat
    80401 ggatggtctg ggagagaacg ttgccaagca actggtgcgg gcgcgtgaag agggagaatt
    80461 cctctctaaa acagaactac gcaagcgtgg tggactctca tcaaccttgg ttgaaaagat
    80521 ggatgagatg ggtattcttg gaaatatgcc agaggataac cagttgagtt tgtttgatga
    80581 gttgttttaa aaaattgctt aataatctat taaaagaggc taacgtatat ccaatagatt
    80641 tacattagct ttcttttttg ttaaaatagt ctatggaaag agggtgagag tatgtcaaag
    80701 atgagtataa gcatccgtct ggatagtgag gttaaggagc aggcccaaca ggtgtttagt
    80761 aatctgggaa tggatatgac aacagctatt aatattttcc ttcgtcaggc aattcaatat
    80821 cagggattac cttttgatgt tagactagac gaaaatcgga agttgctcca agcgttaacg
    80881 gatttagacc aaaatcgtaa tatgagccag tcttttgaat cagtctcaga tttgatggag
    80941 gacttacgtg cttaagattc gttatcataa acagtttaaa aaagatttta agttggctat
    81001 gaagcgtggt ttgaaggcag aattattaga agaagttttg aattttctgg ttcaagaaaa
    81061 agaacatcct gccagatatc gtgatcattc attgacggca tccaagcatt ttcaaggagt
    81121 tcgtgaatgc catacccagc cagattggct tttggtttat aaagtagaca agtcggaatt
    81181 gattttaaat ttgctgagga caggcagtca cagtgattta ttttaatcta ttttaagggg
    81241 gttctcatga aactaagaat atttgcggaa gataagccgg ctaagaaggt atttgaatat
    81301 caattagaac ttgctgatcg tacaattctt ctatcgacag cactcttgtc aggtgctatt
    81361 gctttagcag gaatcttttc tgctttgaaa gaaaaataaa aatagaaaag agaaaacaga
    81421 atggttttac caaattttaa agaaaatcta gaaaaatatg cgaaattgtt ggttgcgaac
    81481 ggaattaacg tgcaacctgg tcacactttg gctctctcta ttgatgtgga gcaacgtgaa
    81541 ttggcacatc taatcgtgaa agaagcttat gccttgggtg cgcatgaggt catcgttcag
    81601 tggacagatg atgtgattaa ccgtgagaaa ttcctccatg ccccgatgga gcgtttggac
    81661 aatgtgccag aatacaagat tgctgagatg aactatcttt tggagaacaa ggctagccgt
    81721 cttggggttc gttcatctga tccaggtgcc ttgaacggag tggacgctga caagctttca
    81781 gcttctgcta aagctatggg acttgccatg aagccaatgc gaatcgcaac tcaatctaac
    81841 aaggttagct ggactgtagc agccgctgct ggacttgagt gggctaagaa agtcttccca
    81901 aatgctgcga gcgacgaaga agcagttgat ttcctttggg atcaaatctt caaaacttgt
    81961 cgtgtctacg aagcagatcc tgttaaggct tgggaggaac atgcagccat tctcaagagc
    82021 aaggccgata tgcttaataa ggagcaattt tcagcccttc actacacagc gccaggaaca
    82081 gatttaacac ttggtttgcc aaagaaccac gtttgggaat cagctggtgc tgtcaatgca
    82141 cagggcgaag aattcttgcc aaatatgccg acagaagagg tcttcacagc gcctgacttc
    82201 cgtcgtgcag atggttatgt cacttctaca aaaccgctta gctacaacgg aaatatcatt
    82261 gaaggcatta aggtgacctt taaggatgga caaatcgtag atatcactgc tgagaagggt
    82321 gatcaggtta tgaaagacct tgtctttgaa aatgcgggtg cgcgtgcctt gggtgaatgt
    82381 gccttggtac cagatccaag tccaatttct cagtcaggca ttaccttctt taacaccctt
    82441 ttcgatgaaa atgcgtcaaa ccacttggct atcggtgcag cctatgcgac tagcgttgtt
    82501 gatggagcgg agatgagcga agaggagctt gaagctgcag ggcttaaccg ttcagatgtt
    82561 cacgtagact ttatgattgg ttctaaccaa atggatatcg atggtattcg tgaggatgga
    82621 acgcgggtac ctcttttccg taatgggaat tgggcaaatt aaggagataa tatgttagga
    82681 agtatgttcg ttggtctcct agtgggattt ttagcaggtg ctatgaccaa tcgtggagag
    82741 cgaatgggat gttttggaaa aatgtttctc ggttggatcg gagcctttct aggtcacttg
    82801 ctctttggaa cttgggggcc agttttatca ggaacagcta ttatcccagc gattttagga
    82861 gccatgattg ttttagctat tttttggaga cgaggaagtt aatttcctaa atctgatact
    82921 caatgaaaat caaagagcaa actaggaaac tagccgcagg ttgctcaaag cactgctttg
    82981 aggttgcaga tagaactgac gaagtcagct aaaaacactg ttttgaggtt gcagatagaa
    83041 ctgacgaagt cagtaacata tatacggcaa ggcgacgttg acgcggtttg aagagatttt
    83101 tgaagagtat gaaacgaaaa ggaggttggt cattgtacca gcctcctttt gatatgatat
    83161 aatagttcta tgagattaga taaattttta gttgcctgtg cggtgggaag tcggactgag
    83221 gtcaaaaact tgctcaaggc tgggcgcgtg actgtaaatg gtaaaaaaga aaaatcagct
    83281 aaattgcaga ttgatgaaaa aatagatgag attcgctttg atgggcaagt gttggagtat
    83341 gaagagtttg tctactacat gatgaacaag cccaaaggag ttatctcagc gactgaggat
    83401 cccaagcaca gaaccgttct ggacttgttg gatgacttgg cgcggagtaa ggaagttttc
    83461 ccagtaggac gcttggatat tgacacgcat ggtcttttgc tcttgaccaa tgatggtcag
    83521 ctggctcatg ttcttctttc gcccaagcgt catgtggata agacttatct ggcacaagtc
    83581 aagggaatca tgacccaaga agatgtggag acatttgctg agggtattcc tctcaaagac
    83641 tttacctgtc aacccgctat actggagctt gtatccatag atacagaaaa gaatcagagc
    83701 caaatccgtg tgaccattgc agaagggaag tttcatcaga tcaagcgtat ggtgggctac
    83761 tgtggcaagg aagtggtgga cttgcaacga ttgactatgg gaactttagt attagatgag
    83821 aacctggaac gaggggaatg gcgtcgcttg accaaggaag aattagaaat tctccgcgct
    83881 aatattattt aatttagttt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
    83941 cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag
    84001 agtataaatt cgaaaaaggt gagggagaat gtccttacct tttatgtttt ttagttgctt
    84061 cctttgtgaa aagagttata atagactgta gaataaaagg aggaatctat gaacgcgatt
    84121 caagaatcat ttactgataa actatttgcc aactatgaag caaatgtaaa ataccaagcg
    84181 attgaaaatg ctgccagcca caacggaatt tttgcagctc tggaacgtcg ccaaagccat
    84241 gtagacaaca cacctgtttt ctcattggat ttaaccaagg acaaggtcac taaccagaaa
    84301 gcgtctggtc gttgctggat gtttgcggct ctcaacacct tccgccacaa actcatctcg
    84361 caatacaaat tggagaactt tgagttgtca caagcccaca ctttcttctg ggataagtat
    84421 gagaaatcaa actggttctt ggagcaagtc attgcgactt cagaccaaga attgactagc
    84481 cgcaaggtta gcttcttact ccaaacacct caacaagatg gtggtcaatg ggatatggtc
    84541 gtttccctct ttgaaaaata cggtgtcgtg cctaagtcag tttatcctga gtctgtttca
    84601 tctagcagca gtcgtgagct aaatgcgatc cttaataaat tgcttcgtca agatgctcaa
    84661 atcttgcgtg atttgcttgt ttctggtgca gatcaagtga ctgttcaagc taagaaagaa
    84721 gacctcttgc aagaaatctt taactttctt gctatgtcat taggacttcc accacgcaag
    84781 tttgactttg cttatcgcga taaagataac aactacaaaa gtgaaaaagg aatcacacca
    84841 caagagttct acaagaaata tgtcaatctt cctttagaag actacgtttc tgttatcaat
    84901 gctccaactg ctgataaacc ttacggaaaa tcttacacag ttgagatgtt ggggaatgtg
    84961 gttggtagcc gtgcagttcg ttacatcaac gttccaatgg agcgcttgaa agaattggcg
    85021 attgcccaaa tgcaagcagg tgagactgtt tggtttggtt ctgatgtcgg ccagctcagt
    85081 aaccgtaagg ctggaatcct tgcgacagat gtttatgact ttgaatcaag catggacatt
    85141 aaacttactc aagacaaggc tggacgtttg gactatagcg aaagcttgat gacccacgcc
    85201 atggtcttga caggtgttga cttggacgaa aatggtaaat caaccaagtg gaaggttgaa
    85261 aactcatggg gagacaaggt cggtacagat ggttactttg ttgcctcaga cgcttggatg
    85321 gacgaataca cataccaaat cgttgttcgt aaggaattgc tgacagcaga agaacaagct
    85381 gcctatggag cagaaccaat tgtacttgca ccatgggatc caatgggagc cttggctaaa
    85441 taaaagcata gaaaaaagga atcagatttt agaacctggt tcctttttag ttgcttgatt
    85501 acatgatgtg aagaacatgt gccacaatac ccactgcgaa gagggcaagg ataatagtga
    85561 ttggagatac ttttttctta agtaagtaca tgcaaagtaa agtaaggagt agtcctgata
    85621 atccaggaat caacatatcc aagttttgtt ggaaagtagt aactttttca ggagtttgag
    85681 acaatccttg tcctacttgt gcgaatgctt cttggatacc tttagaccct tctggcaatt
    85741 tatcccaatg gatataagcc ttttcatcta gttgaacttt agaaacatcg aaagcaaatt
    85801 taatatttac ccagcgttga acaaggacag caagaatgaa catcccaagg atagaagctc
    85861 ctttagtgat atcttgaagg ataccaccag acatatcttt agtgatttct gatccagcct
    85921 tgtatccaat ctcttgaaca taccacaaga atgacatacg aatcaagttc catgcaacaa
    85981 agaagaggag tggccccaag atattgccag taagggcaag tgaagcaccg agagatccaa
    86041 ggattgggcg tactgtaaac cagaatactg ggtcaccgat accagcaaga ggtcccatca
    86101 taccgatttt aaccccttgg atagcagcgt catcgatttc cacaccgtta gcacgttctt
    86161 cttcaagcgc aagagtaacc cccatgactg gagcagctac gtatggatga gtgttgaaga
    86221 actcaaggtg acgctcaaga gcagcgattt gatcttcttt tttagtatag agttttttga
    86281 tagctggaat gagtgtataa gcccagccca agttttgcat ccgttcaaag ttccaagacc
    86341 cttgtaagaa ggttgaacgc caccaaactt ttttacgatc tgatttagtt aattgaagtt
    86401 tttcagtcat gatgttttca gtcctttctt atcttagtag tcttctagga tatcgccgat
    86461 tgggtcgtta gaagttgcgg ctcctccgcc accatttcca ccagttttag aaaggtgaag
    86521 gtagataaga gcgatagcaa caccgatagc accgaatccg attagagtaa tatctgacac
    86581 agcagcgaga acgaaaccaa gagcgaagaa tggccatact tcacgagttg ccatcatgtt
    86641 gataaccatg gcgtaaccaa cggcaacgac cataccacca ccgatagcca taccatcttt
    86701 gagccagtct ggcatggcac taaggatact ttgtacagtt tcagttggta ccataaggag
    86761 aagagctgca ggaagcgcga tacgaagtcc ttggaaaagt agcgcaatga aatgcgcacg
    86821 ctccacagcg ccgaagtcac cttttttagc ggcagcatct gcggtatgaa ccaaaccaac
    86881 tgaaattgta cgaacaatca ttgtcaagaa aagtccagct acggcaagag ggatagcaac
    86941 cgcttgggca acaccgatac cagtcttggt aaagtcacca ccaagaacca tgataatggc
    87001 agcagcgaca gaagcaagtg cagcatcagg agcgatagca gcaccgatat ttgaccaacc
    87061 aagggcaatc atttgaagcg atccaccgag gataatccct gcttccaagt gacctgttac
    87121 aagcccaata agggtacagg ctacaagtgg ttggtgaaat tggaactggt cgaggatgcc
    87181 ttcaagacct gcaaagaagg ctacaacgat tactaaaacc atagaaataa tagacatgtt
    87241 taaaatcctt tcataaataa tggcttattt gacattggct ttgttaatca agtcaaacaa
    87301 atctttttta gaatcatttg gtactttacg gacatcaaat tcaacaccca agtcacgcat
    87361 tttttcaaat gtagcaacat cttctttgtc catagacaaa acggtattga ccaatgtttt
    87421 acctgttgag tgagccatag aaccaacgtt aagagtcttg attggcacgc cgccttcgat
    87481 ggcacgaagg gcatcttgag gtgtttcaaa caagataagg gcatgtgttt ctccaaaacg
    87541 tgggtctttt gaaatctcaa tcagtttttg aattggaacc acgttagcct tgacattacc
    87601 tggagctgct tgtttaatca attctttacg aaggtcgtct ttagccacgt tatctgaagc
    87661 aacgatgata cgatttgctt ttgaatctgg agtccaagca gttgcaacct gaccgtgaag
    87721 tagacgtgtg tcaagacggg caagattgat tttcaattta ccgtctccga taacagttcc
    87781 ttctgggata gcagtttggg caactggagc agctgcagcg cttgcaactt cttcaactgg
    87841 atttagctct tctggaagag ctttgatgcc atctttggct tctttaatga tattagcagc
    87901 gactttttct acacctgcag cagcgtccat gaggcgctct gtgtaggctt gaatcaacat
    87961 cggtaagtta agtcctgtga tgatggcaaa cttacgctca ggattttctc ccatcacgcg
    88021 actagcttgg ttaaatggag aaccactcca aaggtcagcc aaaactagaa cctcatcttc
    88081 tgcgtcaaat gcagcaacag cgttattaaa cttagcgtat agatcatcag gaccttcatt
    88141 tggcataaag gtcacaactt gaaccttttc ttgttcacca aagatcatag atcctgactg
    88201 atgaatacca gcagcaaatt cgccgtggct cgcaataatg attccgatac tcattattgt
    88261 cattcctcct tttttgtttt agttttcatt taagaaaact ttaagactgt ttaagtataa
    88321 accgttttca taaaaaaagc aactatttat cataaaaaat taaaaaattt ttatttttgt
    88381 atgttgatat gttgagtttt tgaggagtaa tcttgaattc ttatttaaaa tttaatataa
    88441 aaaagttgga agaagcttcc aacttttaaa ataggtttct attaaattag tgggtgaagt
    88501 cgagtaccat acgtccttgg atttggcctt tttccatttc gtcgaaaatg gcaacagcat
    88561 cttctactgg acgtttttga acaactggga ctaccagacc ttctgcacca aattggaagg
    88621 cttcttctaa gtctttacga gttccgacaa gagaaccgat gacttggatt ccatcgagga
    88681 ctgttttaac gatgctgagt tccatcattt cagaaggaag accaacagcg acgacgcgac
    88741 caccagcacg aatggagtca acagcctggt tgaaggcaac tttagacaca gcagttacga
    88801 cagctgaatg agctcctcca tcagtttttt ctttaatgag tccagctaca tcttcaactt
    88861 cgaggccgtt aatcacaatg tcagcgccta cttcttttgc aagggtaagt ttgtcattgt
    88921 tgatatcgac tgcgataaca tgagcattga atactttttt agcgtattga acagcgaggt
    88981 taccaagtcc accagcaccg taaagaacaa cccattggcc tggttcaact tttgcttctt
    89041 tgatagcttt ataggttgtt actccagcac atgtgataga agaagcttgg gctggatcaa
    89101 gtccgtcagg aactttgaca gcatagtcag cagttgcgat acattgttca gccataccac
    89161 cgtctactga gtagccagca tttttcactg tacggcaaag ggtttcgcga ccagttgtac
    89221 agtattcgca agtgccacat ccttcaaaga accaagcaac gctgacgcgg tcaccgactt
    89281 taaggctttt cacatctgga gcaatctctt taacgatacc gataccttcg tgcccaagaa
    89341 cacgtcctgg gacttgacca aagtcaccat gagcaacgtg gaggtcggtg tggcaaacgc
    89401 cacagtattc aacttctaca agtgcttccc cagtttcaag tggacggagt actttttctt
    89461 caatagcaac accagtgctt tctggattta caacaacagc tttcatagct atcctccttg
    89521 atattgaccg agaacaggga caacgggact ggattgattt tttgtcaaca gagtcgagtg
    89581 tgacgagctc tcttgtattt atatgtgaag tatatcacaa aaggaagcct tttccaaggt
    89641 tttggagaca aaaagtagaa caatcgatta actggttgat gagactgtga aaagagcaca
    89701 aagaccagct tgcaagctgg tcatactctt cgaaaatctc ttcaaaccac gtcagcttca
    89761 tctacaacct caaagcagtg ctttgagcaa cctacggcta gcttcctagt ttgctctttg
    89821 attctcattg agtatcagta taggttataa gaataagtct tgtagggttt tggcaacccc
    89881 atcttggtcg ttggtaaggg aaatttgctc atctgcataa gggagtagct ctggattggc
    89941 atttttcatg gcataaccct tcccagcaaa agcgagcatt tcggtatcat tgtgttcatc
    90001 tccaaaggca atcaaatctt ttttgtcacg attcattatc ttgagcaagt agtccaaagc
    90061 aaaggccttg ttgacacctt ttggggtaca ttcaaggata ttgagcggac ctccccaggt
    90121 attgatagaa agttgatgct ggtagaaggc gttcatgtct tttgccaagg catatttgtc
    90181 actggctctg gtctgcaaga ggatacagtt agggtccttg gtcaccaatt caggctggaa
    90241 ttgatcttca ggctggaaag cttctacacc aaatagtttg ggattggcaa tttcttcatt
    90301 gggatttgta atgtagaatt ttttacgata ttctccagcg ataaaatcgg cttgaatgtc
    90361 ctctgaacgt tgaaccatat ctagcagata ttttttgtct acagtcaaac acttttcaaa
    90421 atcccaaact tggtctggta aatgagtaag ggatccgttg aagttaatca taggagtgtc
    90481 taagcccagt tcacggtaaa aatcttttga catacggtaa gggcgacctg tcgtaataat
    90541 aacctgatgg cctttttcag caactttttt gatggttttt ttggtaaagt cagaaatttg
    90601 actgtctgag ttgagcaggg ttccatccag gtcaactgca ataatttttt tcgtcatatg
    90661 gacctttcta gtgtgttttc agataagatg tcttctatta taacagaaag caggcagaaa
    90721 agcagattcc aaacaaaaaa tgaaattgga ttaatttctt aaacaaatca aacaaagaca
    90781 ttgaaaaagt gaatgataaa tgatataatt ctattattgt tcgtaaaaat taaaaggaga
    90841 ttgatgatgg acaaattatt taaactaaaa gagaacggta cagacgttcg tacagaggtt
    90901 ctcgctggtt taacaacttt ctttgcaatg agctatattc tctttgtaaa cccacaaata
    90961 ctttcacaaa caggaatgcc tgctcagggc gtcttcctag cgacgattat tggtgcagta
    91021 gcgggtacct tgatgatggc tttttatgct aacttacctt atgcccaagc gccaggtatg
    91081 ggactcaatg ccttctttac ctttacagtt gtattcgggc ttggttattc ttggcaagaa
    91141 gccctagcta tggtcttcat ctgtgggatt atttcattga ttattacctt gacaaatgtt
    91201 cgtaaaatga tcattgaatc gattcccaat gctcttcgct cagctatttc agctggtatc
    91261 ggtgtcttcc ttgcctatgt agggattaag aatgctggac ttttgaaatt cacgattgat
    91321 ccaggcaact atactgttgt aggagaaggg gctgacaaag ctcaagcaac gattgcagca
    91381 aactcttcag cagttccagg attggtcagc tttaataatc cagctgtttt agtggctctt
    91441 gcaggacttg ccattactat cttctttgtc atcaaaggga ttaaaggggg aattattctc
    91501 tctatcttga caacaactgt tcttgctatt gcagttggtt tggttgattt gtctagtatc
    91561 gattttgcta ataaccatgt tggtgcagct tttgaagatt tgaagacaat ctttggtgca
    91621 gctcttggtt cagaaggttt gggagctttg gtttcagata cagctcgctt gcctgaaact
    91681 ctgatggcca ttcttgcctt ctcattgaca gatatttttg acacaattgg taccttgatc
    91741 ggtacaggtg aaaaagttgg tatcgtagcg acaaatggtg aaaatcacca atcagccaaa
    91801 ttggataagg ctctttactc tgatttgatt ggaacgacag tcggtgccat tgcaggtact
    91861 tcaaacgtaa cgacttatgt tgagtctgct gctggtatcg gtgcaggtgg acgtactggt
    91921 ttgacagcct tggttgtagc tatctgtttt gcgatttcaa gcttctttag cccacttcta
    91981 gcgatcgtac caacagcggc tacagctcca atcttgatta tcgttgggat tatgatgctt
    92041 ggtagcttga aaaatatcca ttgggatgat atgtctgaag cagttcctgc cttcttcaca
    92101 tctatcttta tgggattcag ctactctatc actcaaggga ttgcagttgg tttcttgact
    92161 tacactttga ctaagcttgt caaaggtcaa gttaaagatg ttcatgccat gatttggatt
    92221 ttggatgcct tgtttatcct taactacatc agcatggcct tataatagaa tgacccaggg
    92281 ggatttcccc ctttttttaa tacaaaggag ataggtgatg aaagagaaaa atatgtggaa
    92341 agaattgttg aatcgtgcag gctggatttt ggtcttttta cttgccgtcc ttttatatca
    92401 ggttccccta gtggttacct ctattttgac tttaaaagaa gtagccctgc tacagtcagg
    92461 gctgatagtt actggccttt caattgtggt tctggctcta tttattatgg gagctcgtaa
    92521 aaccaagtta gctagtttta atttttcttt ttttagagct aaagatttgg cacgtttggg
    92581 cttgagttat ttagttattg tcgggtcaaa tatacttggt tctatcttgt tgcaactgtc
    92641 aaatgagacg acaacagcta accagtctca gattaacgat atggttcaga atagttcctt
    92701 aatttccagt ttcttcttgt tggccttgct tgctccaatt tgtgaggaaa tcttgtgccg
    92761 tgggattgtt cctaaaaaga ttttccgagg aaaagagaac ttgggatttg tagtcggtac
    92821 ggttgtgttt gctttattgc atcaaccaag taatttacct tctttattga tttatggagg
    92881 tatgtcgatc gttctatctt ggacggctta caagacccaa cgtttggaaa tgtctatctt
    92941 acttcacatg attgtgaatg gggttgcttt ctgtttgttg gctctcgtgg tgattttgag
    93001 tcggacatta gggatctctg tttaagattt ttgacaattg cttacttgtt tctactggga
    93061 aaaagatgaa tgcaattgtg tccatctttt tctttttatg gtaaaataga gaaataatat
    93121 ggtgaaaagc cttgagggag tgaccgatat gtcaagtaaa gccaatcatg caaagacagc
    93181 tatttgcgga attatcaatg taaccccaga ctccttttcg gacggtggtc aattttttgc
    93241 tcttgagcaa gcactccagc aggctcgtaa attgatagca gaaggggcta gtatgctaga
    93301 tatcggcgga gaatcgactc ggccgggaag aagcagctat gttgagatag aagaggaaat
    93361 ccagcgtgtt gttccagtaa tcaaagctat tcgcaaggaa agtaatgtcc tcatctctat
    93421 tgatacttgg aagagtcagg tagcagaggc tgctttggct gctggtgcca atctagtcaa
    93481 tgatatcact ggtctcatgg gtgatgaaaa aatggcccat gtggttgcta aggctggagc
    93541 gaaagtagtc attatgttta atccagtcat agcacgacct cagcacccta gctcgctcat
    93601 ctttcctcat tttggttttg gtcaagcttt tacagaaaaa gagttagctg actttgaaac
    93661 attgccaata gaagacttga tggagacttt ctttgacaga gccttagcga gagcagagga
    93721 agctggtatt gcacaagaaa atatcttgtt ggatccagga attggctttg gtttgaccaa
    93781 gaaagaaaat ctgcttcttt tacgggatct ggataaacta catcagaaag gctatccaat
    93841 ctttctcgga gtgtcgcgca agcggtttgt catcaatatt cttgaagaaa atggttttga
    93901 agtcaatcct gagacagaac ttggtttccg caatcgagat acggcttcgg ctcatgtaac
    93961 cagtatcgct gtgagacagg gtgtggaagt ggtgcgcgtg catgatgtag ctagtcacag
    94021 gatggcagtt gaaattgcct ccgctattcg tctggctgat gaagcggaaa atttagattt
    94081 aaaacaatat aaataagatg aaagaatttg aaaacaatca gtggattgct aactaccgga
    94141 cggatcaacc gcattttggc ttggaacgaa tggtggaact gttagctttg cgtggcaatc
    94201 cccatctcaa actcaaggtc atccatatcg gagggactaa cggcaagggt tcgaccattg
    94261 cttttttgaa aaagatgcta gaaaagctag ggctgagagt tggcgtgttt agctctccct
    94321 atctcattca ttacacagac cagattagca tcaacgggga atccattcca gaggctaggc
    94381 tagaagccct catggcagac taccggtctt tgcttgaggg ggaatcggct accaatttgc
    94441 aggggacaac tgagtttgaa ataattacag ccatagccta tgactacttt gccttagagc
    94501 aagtagatgt ggccatcatg gaagttggca tgggtggact tttggatagt accaatgttt
    94561 gccagcccat tttgacaggc atcaccacta ttggactgga tcatgtggcc ctacttggtg
    94621 acaccttgga ggccatagca gagcagaagg caggcattat caaacaagga actcccttgg
    94681 tgacaggtcg tatcgctcca gaagccttgg ctgtgattga ccgcattgcg gaagggaaag
    94741 atgcgccgag acttgcctac gggacagatt atcaggttcg tcatcaagaa agtgtggtga
    94801 caggggaagt ctttgactat acaagtgctg tcagacaagg tcgcttccag actagcctgc
    94861 ttggtttgta ccaaatagag aatgctggga tggccatagc tttacttgat actttttgtc
    94921 aagaagatgg tcgagagcta gcaagcaatg actttcttgg tcaagccttg gaagaaacaa
    94981 gttggccagg gcgtttggaa atcgtgtcaa gagatccctt gatgattttg gatggagccc
    95041 ataatcccca tgctatcaag gccttgttgg taaccttgca agaacgtttt gcggattatc
    95101 ataaggaaat cctcttcact tgtatcaaaa ccaaagcctt gggggatatg ttggacttgc
    95161 tgggagctat gccagatacc gagcttactc taacacattt tgcggatagt cgggcgacgg
    95221 atgaaagcgt gctgaaagag gcagctaagt ctagaaatct cagctaccaa gattggcatg
    95281 attttctaga gcagaatttg acagataaaa aagaagagaa acaaacagtt aggattgtca
    95341 caggttcctt gtatttcttg agccaagtga gggcctatct gatggagagg aagaacgaga
    95401 atggatacac aaaagattga agcagctgta aaaatgatta tcgaggctgt aggagagaac
    95461 gctaatcgcg agggcttgca ggaaacacct gctcgtgtag cccgtatgta tcaagagatt
    95521 ttttcaggtc ttggtcaaac agcagaggaa catttgtcaa aatcctttga aattattgac
    95581 gataatatgg tggtagaaaa ggatatcttt ttccatacca tgtgtgaaca ccacttcttg
    95641 ccattttatg gtagagcgca cattgcctac attccagatg gtcgtgtggc aggcttgtct
    95701 aagctagccc gtacggttga agtttattcg aaaaaaccac aaattcaaga acgtttgaat
    95761 atcgaagtgg ccgatgcctt gatggactat ctaggtgcta aaggagcctt tgttgtcatt
    95821 gaggcggaac atatgtgtat gagtatgcgt ggtgttagaa aaccaggcac tgcaaccttg
    95881 acgacagtag ctcgtggtct atttgaaaca gataaggacc tccgcgacca agcttatcgt
    95941 ttaatggggc tataaaaaga atccgtttca agcggatttt tctagaaagg aatcattatg
    96001 gatcaactgc agattaagga tttggaaatg tttgcctatc atggtctttt tcctagtgag
    96061 aaagaattgg ggcagaaatt tgtcgtttca gccatcctat cctatgatat gaccaaggca
    96121 gctacagact tggatttaac agcctctgtc cattacggag aattgtgtca gcagtggacg
    96181 acttggtttc aggaaacgag tgaagatttg attgaaacgg tagcctataa actggtggaa
    96241 cgtacttttg agacctatcc tcttgtccaa gaaataaagc tggaactaaa aaaaccttgg
    96301 gcaccagtgc atttgccact agatacttgc tcggtaacca ttcatcgccg caagcaacga
    96361 gcctttatcg ccctaggaag caatatggga gataaacaag caaacttgga gcaagccatt
    96421 gacaaactgc gagctcgtgg catccatatt ctcaaagagt ccagtgtctt agcgacggag
    96481 ccttggggtg gagtggagca ggatagcttt gctaatcagg tgattgaagt agaaacctgg
    96541 ctaccagcac cagtcttgtt agaaaccttg ttagccattg agtcagagat gggacgggtg
    96601 agagaagtgc attggggacc tcgtttgatt gatttggact tgctctttgt ggaggaccag
    96661 atcctttata cagatgacct tatcttgcct catccttaca tagcggaacg cctttttgtc
    96721 cttgagtcct tacaggaaat tgcgtctcat tttatccatc cgacattaaa gcaaccgatc
    96781 cgcaacttgt ataatgcttt gaaaaaataa aaaaactcta gttttcagtc atttgtaact
    96841 gaagactaga gtttttaaaa taggtcattt tcttctggga ggaggatagt ttctctacca
    96901 tccatgtcta aaaccagtac tcttggcgga tatagagggt caaaaggatg gttaaagtca
    96961 aaatcaatag ctgtagggag gtgttgactt gaaaaatgga aggtaatttt tccttggtta
    97021 ttgagcaatt gaaactcaag ttcttcttcc aattcaaaga cattttttaa gaaatggtcg
    97081 ataatatacc aaaaagagtc aatgatgtca tcaggcaagc tggtaacaat gccaaaacta
    97141 gcagaccgca tgtgggtatt ggtaaaagcc atatctctgt ctcctttctt ttcccttatc
    97201 atacagcaaa taggattaaa aatcaagaaa aggtgatttt ttgaaaagga ttttaactac
    97261 agggaaaaag aaggaaaaaa attcccaaaa atctaccgaa gttaataggt aaattcccaa
    97321 attaacttga ttatataact ttcagttact ttgagaagtt accgaaaaat atttttcata
    97381 tctattgact tttaggggtg aaatttggta tgatagtagg cggtattgtt taccccattt
    97441 gaaaggcccc ggaaccttcc aaatactttt cgatgggaag gaacacccat caccgtaaac
    97501 aaaaatcgaa ctatatatag gagaaatcat gaacaaaaca acatttatgg ctaaaccagg
    97561 ccaagttgaa cgtaaatggt acgtagttga cgcaactgat gtaccacttg gacgtctttc
    97621 tgcagtagtt gctagcgtac ttcgcggaaa aaacaaacca acatttacac cacacactga
    97681 tacaggtgac ttcgtgattg ttatcaatgc tgaaaaagtt aaattgactg gtaaaaaagc
    97741 aactgataaa atctactaca ctcactcaaa ccacccaggt ggattgaaac aaatctctgc
    97801 aggtgaactt cgttctaaaa atgcagtacg tttgattgag aaatcagtta aaggtatgct
    97861 tccacacaat acacttggac gcgctcaagg tatgaagttg aaagtatttg ttggagctga
    97921 gcacactcat gctgcacaac aaccagaagt tcttgacatt tcaggactta tctaaggaaa
    97981 ggaacaaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
    98041 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
    98101 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
    98161 caactgtagg ttcatacgac gttttcgtta acgttgtagg tggtggatac gctggtcaat
    98221 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
    98281 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
    98341 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
    98401 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
    98461 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
    98521 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
    98581 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
    98641 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
    98701 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
    98761 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
    98821 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
    98881 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
    98941 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
    99001 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
    99061 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
    99121 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
    99181 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
    99241 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
    99301 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
    99361 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgagtcttat
    99421 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
    99481 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
    99541 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
    99601 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
    99661 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
    99721 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
    99781 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    99841 gacaagctag taaggttaga atactctcaa actggaaatt ttgaggatag aacgacacaa
    99901 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    99961 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
   100021 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
   100081 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
   100141 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
   100201 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
   100261 tttgcttatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
   100321 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
   100381 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
   100441 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
   100501 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
   100561 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
   100621 gaagaagctt atcctcaaat cgcaaaacga ttggggttaa atgtagaact agaagaacct
   100681 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
   100741 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
   100801 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
   100861 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcactgcta ccctgttggt
   100921 ttttcagggg atactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
   100981 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
   101041 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
   101101 cgattacata gttctagaag tccttttaat agtaaagaac cttggttttt ttcagaaaca
   101161 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ttatctatat
   101221 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
   101281 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
   101341 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
   101401 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
   101461 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
   101521 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
   101581 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
   101641 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
   101701 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
   101761 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
   101821 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
   101881 ttaaaagata gattgttaaa tcaattcatc aatgcgaaaa actctcatga cttaatgaat
   101941 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
   102001 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
   102061 tattcgttat cactggtcac attgaaaatg tgaaataagc acctacaaca tagactttac
   102121 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
   102181 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
   102241 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
   102301 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgattcgttt tcctagtggg
   102361 ccagatttct ggtcttgtaa ccagacatag agagggtctg cttccttacc gttgacctta
   102421 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
   102481 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcaaag
   102541 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
   102601 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
   102661 gcttggttgt tttggttcaa aaaggaaaaa tcataaagtg aagtcatgag ggcctctttt
   102721 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
   102781 aagaataagc cctcaatatg atagaaaccg tttacaaata actttaaaaa tggtatgatt
   102841 taattaaacc gatttactta gttgctataa atctctaatt tgagatttag ttcctattga
   102901 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
   102961 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
   103021 aagaaacgac tacgaatact attcagcaaa gccagaagga agttcagtat cagtaaaggg
   103081 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagtccgt
   103141 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
   103201 atgcctcaac tcgagtcatt gaggctaagg atggagctat cactatctca agccctgaga
   103261 aattaagggc agcggttcac cgtatggttc ctattgaagc taagaaaaag tataaactgc
   103321 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
   103381 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
   103441 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
   103501 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagacc
   103561 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
   103621 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
   103681 cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca
   103741 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggatg
   103801 catacacagc ccgtttggat gactggactg gcatcatcgc tgggaatcaa tactatgatt
   103861 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
   103921 tatctagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
   103981 aaatgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
   104041 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
   104101 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
   104161 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
   104221 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
   104281 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
   104341 tgggaagggt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
   104401 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
   104461 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
   104521 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
   104581 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
   104641 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
   104701 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
   104761 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
   104821 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
   104881 caggagtcgc aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa
   104941 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
   105001 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatgtga
   105061 tgttctatct ttacaatggc gatttgaatc actatagcga tggctactgg ccaacagtca
   105121 atccatataa gatgcctggt acaacagaga cggatgctga gagagcggat agcgatacag
   105181 gtaaagttct accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
   105241 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
   105301 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
   105361 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
   105421 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
   105481 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
   105541 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
   105601 aggaagttga aaatgaattt cttacgatta gtcaggatca taagcaaaat ggagattctt
   105661 atggctatat gctcatccct aacgtggatc gtgccacctt caatcaaatg ataaaagagt
   105721 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
   105781 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
   105841 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
   105901 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagtaag
   105961 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
   106021 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
   106081 ggttcttgct acttggggcg ttttatctat tccgtagagg aaagaacaac taatttgttc
   106141 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
   106201 atcttcggat ttttctttta aaaagggata agttgatact tatccttttt tacttcatta
   106261 tgtgactata gcgttttgaa actagaatag tacgtcataa ctgctaaaag atttctataa
   106321 attcatttga ttttcctaat caatttgttc gtatcctatt tcactccact atattagtcc
   106381 gtctcgctcc gtgaggtgcg agacaaaaca accacccgct atgcgggtgc gcgtcgaagg
   106441 ttataccaaa aaaactccaa acgcgataca ataaaggtgt tcaatccaat tgtaaagcga
   106501 aaggagaaaa aatatggcac aaaaggctca tagtttatct cacacaaagt ggaggtgttc
   106561 tatcacattg tgttcacccc taagtataga cgaaaagtca tctataatca atatagaagt
   106621 agtttaggcg aaatatttca tcgcttgtgt agttataaag gtgttgaaat gatcgagggt
   106681 cacttaatgc cagaccatgt acacatgtta gtcagtattc cactaaggct aagtgtttcg
   106741 agtttcatgg gttatttaaa aggcaaaagt gcactcatga tgtttgacaa acacgccaat
   106801 ctcaagtaca agtttgggaa tcggcatttc tgggtggaag gttattatgt aagtacagta
   106861 gggcttaata aagccacaat taagaaatat agtcaagatt aaagaaatta tccagtggat
   106921 gatttcttca cgagtatgaa aatttgagaa cgagtaaagc atgatatata gtaaaatgaa
   106981 ataagaacag aacaaatcga tcaggacagt caaatcgatt tttaacaatg ttttagaagt
   107041 agaggtgtac tatttcagtt tcaatctact atagcactag ataaattgag tgtaaaagaa
   107101 tatgaggatc cctttaggga tagtggtaag taataccaaa gtctcttaaa gaggcaagtg
   107161 acgagtcaag agcaataagg cttgaacaac gtgaaagcca gcgtctttag gcgctggctg
   107221 gtaatttggg cttatagctc tgggataaac cacctgtttg acgggtggtt atgattttat
   107281 ctgagtgtaa catactgttg ggcaatctcg ctgatgcggt caaagttgcc ttgggaagcg
   107341 agtttattga gttcgccacc aattccaacg gcgtctgcac cagcagcgaa ccattgaggg
   107401 atgttgttta gaccgactcc tccggttacc attacggaaa cttgtgggat cggtgccttg
   107461 actgcagaga tatatgctgg actgagagca ctacctggga agagtttgat gatttcacta
   107521 ccggcttcaa gtgcagtcgt gatctctgtg agggtaatac agcctggaat gtacggtgtg
   107581 ctgtagagat tgcacatttt cgcagtttca gcatggaaag atggagaaac aacgtaattt
   107641 gctccggcta gaatggcatc tctagcagtt acggcatcaa gcacagtacc tgcaccgata
   107701 caaacactct gatcgtcctg atacaagtct acaagttcct tgatgatttg tcctgcatac
   107761 ggattggtat aggcgatttc aatagctttg ataccgccct tgatacaagc aatcgaggct
   107821 tgcagtcctt cttcctttgt attccctcga atgacagcga caattttctg tttttttagt
   107881 tcaataatcg tatctgattt ggtcatgtaa ttctcctaac gaatgatatc ttgtgcattt
   107941 gccagtaaat tttcaatact agttgcggaa gtggagagat ggtctcctgg aagagtgcat
   108001 ttgagagttg cgctcgcaac tgcaaagtca atggtagttt ttagggagga atgatggagt
   108061 agttggtaaa gggcaccaga tataaaggca tccccgctac caattcgttg atagactgca
   108121 gtttttagtt ggacagactc ttcaaatcgt tcttccagag cataggcttg atagacattt
   108181 ttgtcttgct catcactaga gcggagggta tggaaaatgg ccttgaaacc ataggcttct
   108241 tttaaaagtc gcatgcgatt ttccacctct tctaggctag cactgtctct tggaaacatc
   108301 tctagatttt ggtcatcaat catgagagga tcaataccga agcaatagtc agtaaaacgt
   108361 acaaacttag aaaattcata cttggcttct agaactgaaa tcatctttgt tctcagattg
   108421 agatccattg aaacgacaat tcctcggcgc ttggcttctt ccaagagtag gagaaggatc
   108481 gtacggacct cttgaccgat agctacggtg attccactaa aatgaaaatg gctaatcccc
   108541 tgaaagagag aatccatatc tagcatgttt ggccgaatct ggctgatact cgtatgctta
   108601 cgatcgtaga aaacttcact ttgacgacaa ccaaagccgt tctccaaata gtagaggccg
   108661 attcgatagc caagccgaca gattgaactg gtatcgattt ggtgctgttt caagaatgtg
   108721 agaaaacgat ctccaatctc gttggcaggg agtgcggtaa agactttcgt tgagataccc
   108781 agggcttgca aattacaagc gatgttaatt tctgatccgc caaaataagt cgaactggca
   108841 acatgatctc cgatactggt ggcatctaat ggtgagattc gaattaatgg ttcgccaaac
   108901 agtaatattt tcgtcatcca ttagttcctt tctggtttag aatggcttta cttggctaat
   108961 acttctttca aataagcagc gacttcatca tcttggcagt tttcaaagaa gtattcttgg
   109021 aagtatttgc cagagatggt gtctttgagg aagtcttggt cgattgtttt aaggatggtc
   109081 atcaaatcat tgtgggtgat ttgtttcacc tcgtttaaga tacgagcgtt gcgttgttca
   109141 gggactacac gttctcttgg gtagccaccg cccatttctt cagcaaataa gcgttcaaac
   109201 attaatttga gggtcagttc tgccccccag ccaaatcctt tggcataagg gatagacaag
   109261 gcgttaccac cattgatttg agaataaagg taagcgtcag ttgggtccac tgctagacca
   109321 cagacaacac cagggaagct gtttaaagca agcatagctc ctacacccgt accacagccg
   109381 gtaacaacaa agtcgactgc ttttgtattt aaaaggatgg cagccattag gccgttttgt
   109441 acgtatgtta atgggttttc accttcttct ccacgcatac catagttaaa taattggtag
   109501 ccttttttat ctgtcgcttc ttttagacta tcgtaaataa tgtgattctt gctagcttga
   109561 ctattttcat tgattaatgc gattttcata agatcttctt tctattttta ctcaggttgt
   109621 tttccgatgt aggctaagat accgccatct acatatagga tgtggccatt gacaaagtcg
   109681 ctggcatcac tagcgagaaa gacagcaggg cccattaaat cttcaggatt tccccaacgt
   109741 gcagcaggtg tttttgcaat gatgaactgg tcaaatgggt ggcgagaacc atcttcttgc
   109801 aactcacgaa gaggtgctgt ttgaggagtg gcaatataac ccggtccgat tccgttacat
   109861 tggatattgg ctccaccgta ttcagacgca atattgcggg tcaacatttt caagccgcct
   109921 ttagcggcag cataagcgct aaccgtttca cgtcccagtt cgctcatcat cgagcaaata
   109981 ttgataatct ttccatgccc tttctttatc atagaaggaa tgactgcttt tgaaacgata
   110041 aatggtgcgt ttaagtcaat atcgatgacc ttacggaaat cagcggcgct catttcgcac
   110101 attggaacgc ggcggataat accagcgtta ttaacgagga tgtcaatgac accaacctct
   110161 tgttcgattt gcttgaccat ggcttggata ccgtcctcgt ctgtcacgtc acagacatac
   110221 ccatgggctt cgatgccaac ttcacgataa gcttcaatcc ctttattgac caggtcttga
   110281 ttgatatcat taaagacaat agtagcgccg acctcagcgt aggatttggc aatagcaaat
   110341 ccaattccat aagaagcgcc ggtgatgaga gcaatttttc cttttaaaga aaactgttca
   110401 attgagaatg atgtatttgt catttgatac ttcctttcaa atttgttaag acttctctat
   110461 aaccaaatta tattctagta aaccggtttt gtcaatgatt aaatattttt atttctgaaa
   110521 atctttgttt tcctaaaaaa acggaagatt ttgaagtttc tgtctattgt aatggttaaa
   110581 taagcaatga aagcgctaat atttttttga aaaaactatt gacaagataa aaataaaggt
   110641 ctacaatgta aaatatagag taaaccggta aactcaaaaa gaaaggagaa aagatgaaaa
   110701 ttgtacttgt agggcatgga cattttgcca cagggattta tagttcttta caattgattg
   110761 caggcaatca agaaaatgtg gaggcgattg actttgtgga aggaatgtca gcagatgaac
   110821 tcaagcaaaa aatcttactt gcaatttcaa atgaagaaga agttttaatc ctaagtgatc
   110881 tcttgggagg atcgccattc aaggtttctt ctaccataat gggagaaaat ccagccaaaa
   110941 caatgaatgt tctctcgggt ttgaacttag ccatgttaat ggaagcagtc tttgctagaa
   111001 tggctcatag ctttgatgag gttgttaata aatcagtagt ggcggctcag ggcggagtcg
   111061 taaatggtaa agaattgttt tcaacggatg cagaggaaga ggaagaagat ttcgaatcgg
   111121 gtatttaaag ggtaaaagaa tgataaaaaa ggttacgatt gaagaaataa aatcgcctga
   111181 gcgcttctta gaagtaccac ttctgacgaa agaagaagtc gaccaggcaa tcgataaggt
   111241 tattcggcag ttagaactca accttgacta tttcaaggaa gatttcccga cgccagctac
   111301 ctttgataat gtctatccaa tcatggataa tacggaatgg accaatggtt tctggacagg
   111361 agaactgtgg ttggcttatg aatacagtca acaggatgaa tttaaaaaca tcgctcataa
   111421 aaatgttctt tctttcctgg atcgtgtcaa taagagagta gaattggatc accatgatct
   111481 cggcttcttg tacacaccgt cttgtatggc tgaatataag ataaatggag atggagaggc
   111541 cagagaggca gccttgaaag ctgcagataa gttgattgaa cgctatcaag aaaaaggtgg
   111601 ttttattcaa gcttggggag acttgggcaa gaaagagcat taccgtttga ttatcgactg
   111661 cttgctcaac atccaactct tattctttgc ttatcaagaa acaggcgatc aaaaatacta
   111721 cgatattgca gaaagccatt tctatgtttc agctaataat gtaatccgtg atgacgcttc
   111781 gtccttccac accttctact ttgatcctga gacaggtcaa ccccttaaag gtgtaacgag
   111841 acaagggtat agtgatgatt catgctgggc acgtggtcaa tcatggggag tctatggtat
   111901 tcctttgact tatcgtcacc tgaaagacga gtcctgcttt gacttgttta agggtgtaac
   111961 caattatttc ttgaatcgtc tgccaaaaga tcatgtttct tattgggatt tgatttttaa
   112021 tgatggtagt gatcaatcac gagattcttc agcaacagct atcgctgtct gtgggattca
   112081 tgaaatgcta aaacatctcc cagaggtgga tgctgacaaa gatatttata aacatgctat
   112141 gcatgccatg cttcgttctt tgatcgaaca ttatgcaaat gatcaattta cccctggtgg
   112201 gacaagtctc ctccacggtg tgtactcatg gcattcaggt aaaggagtgg acgaaggcaa
   112261 tatctggggt gactactatt acctagaagc ccttatccgt ttctacaagg attggaacct
   112321 atattggtag gaggagaaat atgacaatgc caaatattat tatgacccgt atcgatgaac
   112381 ggttgattca tgggcaagga caactttggg taaaatacct aggttgtaat acggtcattg
   112441 ttgccaatga tgaagtaagc acggacaaga tgcaacaaac tctgatgaaa acagttgtac
   112501 cagactcagt tgccatgcgt ttcttccctt tgcaaaaggt gattgatatc attcacaagg
   112561 ctaatcctgc tcaaacgatc tttatcgttg taaaggatgt aaaggacgct ttaaccttgg
   112621 tagaaggtgg tgtccctatc aaagaaatca atattgggaa cattcacaat gcccctggta
   112681 aagagcaagt gacacgctct atcttcctgg gtggagagga caaggcagct ctcaaggaat
   112741 tgaaccaaac ttatcaagta acatttaata cgaaaacaac tccaacagga aatgatggag
   112801 ctgttgaagt caacattatg gactatattt aaaagaggag atcgttatgt cgattaatgt
   112861 atttcaagcg attttaattg gattatggac agctttctgt tttagtggaa tgctgttagg
   112921 aatttacacc aatagatgca ttgttctgtc atttggtgtc ggaattattc taggtgattt
   112981 gcctactgct cttgcaatgg gagctattgg tgaattggct tatatgggat tcggtgttgg
   113041 tgctggaggt actgttccac caaacccaat cggacctggt atctttggta ccttgatggc
   113101 tatcactagt gctggtaaag tcagtccaga agcggctctt gccctctcta ctccgattgc
   113161 tgtggcgatt caattcttac aaactttcgc ctacactgta cgtgctggtg cgcctgaaac
   113221 ggcgatgaag cacttgaaaa accataattt gaagaaattc aagttcactc taaatgcaac
   113281 aatttggtta tttgccttta ttggatttac cttgggttgc ttgggtgccc tttcaatgga
   113341 taccttgttg aaactcgtag actacattcc accggtattg cttacaggtt tgacagttgc
   113401 tggtaaaatg ctcccagcta tcggttttgc gatgatcttg tcagtgatgg ctaagaaaga
   113461 gttgattccc tttgtcttgt tgggatatgt ttgtgcagct tatctaaaca tcccaacaat
   113521 tggtattgca attgtaggta ctatctttgc tttgattgaa ttttataaca agccaaaaac
   113581 agcgaatcat gtggtagagg aggaagcaca cgatgactgg atctaacaaa ttaacaaaac
   113641 gtgattatct taaaacgtct ttgcgggcat tcttttgtca aaatggattt aactatagta
   113701 actatcaagg gttgggatat gccaatgtga tgtatcctgc tttgaaaaaa cactatggag
   113761 aggatcagga aggtttctac caagccttgg aagaaaactg tgaattctat aataccaacc
   113821 cacacttcct gccttttatt accagtttgc accttgtaat gttggaaaat ggccgtccgg
   113881 caaaagagac acgtagcatc aagatggcct tgatggggcc attggcaggt attggggatt
   113941 ctctttctca attctgttta gctccattgt tctcaaccat cgccgcttct tttgctcaag
   114001 aaggcctggt tgtcggtcca atcttgttct tcctagcgat gaatacgatt ttgacagcga
   114061 ttaaattgtc aactggtctc tatggataca aactaggaac gactgtgatt gataaactaa
   114121 gtgaacagat ggcaacgatt tctcgtattg ctaatattat cggtgtaacc gtaattgctg
   114181 gtttggcagc gacatctgtg aagattatgg tgccaatcac ctttgctgca ggggaagtta
   114241 aagcagatac caaacaaagt atcgtaagta ttcagggaat gcttgataag gttgctccag
   114301 ctcttctacc agccctattt acacttttag tttactactt gatcaaagaa aagaaatgga
   114361 caacatataa actcgttatt ttaacagtta tcatcggaat tatcggaagc tggcttaaga
   114421 ttctagctta atggatacaa cattgtttta tggaatagtg attgtcttgg cagtgagccc
   114481 ccttttactg tcaagctttc attctattcg tcagcaaaag ttgcttcgca aacagatgga
   114541 gcaacgaaaa gagtatttag cttctttaac atctggtgat gaagtgttgt tattgtctgg
   114601 aattcatgga aaaatcattt ctatcaaaga tgacttggtc tccttgcaga ttgcaaaagg
   114661 tgtggtcatc tatgtagaaa aggaaagtgt aatgggaaag acaaaagaac tgctttttaa
   114721 gtagttcttt ttctggtaat agataatgaa agaagaaaga agacaatttt ttgaaaaaat
   114781 tgatggggat caatatcgtg attatatctt gtcccactgt tcacaagact atgagaaagt
   114841 caagcgttcc cttgaacgct tgatggacaa tcgttttatg tttgatagtc cttgggatat
   114901 ggaaccttgt tcaaaaatcc atcaaatcca gccgatggtg tggaatcaag tatttgaaga
   114961 tgatccagaa tgggcttata tgctcaatcg acaagaatat ctcttgcagt ttatgatagg
   115021 gtacctggta gaaggagata agggctatat ccaaaagtgc aagttctttc tatttgattg
   115081 gattgagcag gtgagagaat ttcgtcctca atctttgatg actagaacct tggatacggg
   115141 tattcgttcc tttacttggt tgaaactact cttgctcctc ttgaaatttg acctgctaga
   115201 ggaggaagaa ctagagaaca ttttggtcag tctagaaaag cagattgact ttatgaaaag
   115261 ccattatcgc gccaagtaca cccttagtaa ctggggaatt ttacaaacga ttccgatact
   115321 tgcaacctat catttctttt cagataagat ggacctagaa gaagcttacc attttgcttc
   115381 aaaggagttg aaacagcaga tcgagacgca gattttagag gatggaagtc agtttgaaca
   115441 gtcgattctc tatcatgtag aggtttataa agccttgctg gacttgtgtc tcttgcttcc
   115501 ggacttgcaa gatagctttc aagagctgct ggaaaagatg gcgacttaca ttcaaatgat
   115561 gacaggtcta gatggacgga ccttggcttt tggtgatagc gattctacag aaacgacaga
   115621 gattttgagc ctgtctgcta tggttttgaa caaggaagac cttcttaacg gtctggatgt
   115681 taaagtcgat ttacttagcc tcctgttcct ggggcgagaa aaggtcaagc gactgcagga
   115741 atttgaaaag agagcttggc agcctaagtt caggagcttt gaagattctg ggcatgtttg
   115801 cattaaggat gaacatcgtt atctattttt taaaaacggt ccgctgggaa gtgcccatag
   115861 ccatagtgac gagaatagtt tttgcttaca gtatcaaggc caaccgattt tcatagatac
   115921 tgggcgttat tcttatcggg aggtagatga acgttatctc ttaaagagtg cttggagtca
   115981 ttcgacctgt atagtagatg ggaaagctcc agaaaggatc gtgggatcct gggaatatga
   116041 atactatcct cactccctgt tttgtcacca caaagaaaga gagggagtgc attatattga
   116101 gggggcgtat ttgtcagcag aacctgattt gccttatctt cacaggagaa aaatcctcat
   116161 gttggcagag gatgtatggc tcttggtaga tgatatcagg tgtcaaggtc agcatgaggc
   116221 gttgactcag tttatccttg acaaggatgt gacctatcaa gatgggaaaa tcaatcagtt
   116281 gaaactatgg agtgaagttg attttgattt ggaagctacg atcatttctc ctaaatacaa
   116341 cgagcttgaa aaaagtagca aactcatcaa acaccaattc tttgagaatc agatgctgga
   116401 ttatacaatc attgcgcatg agagttttga aatcatccgt cattctgtct accagacaga
   116461 tggtcatcaa gtagaaaatg ctctggcttt tgaagtgaaa aatgacgaaa cagacaagct
   116521 gattctgtta ttaagcgagg atatttgtgt aggtgaaaaa ttatgcctcg ttgacggaac
   116581 aaaaatgcgt ggaaaatgtc tagtatatga taaaataaat gagagaatga ttcgcttgca
   116641 gtgctagaaa tagacgtttt gaatagtgaa tatgttataa tgggtattag taggaggtgt
   116701 tttagattgg agaagaaact gaccataaaa gatattgcag aaatggctca gacctcgaaa
   116761 acaaccgtgt cattttacct aaacgggaaa tatgaaaaaa tgtcccaaga gacacgtgaa
   116821 aagattaaaa aagttattca tgaaacaaat tacaaaccga gcattgttgc gcgtagctta
   116881 aactccaaac gaacaaaatt aattggtgtt ttgattggtg atattaccaa cagtttctca
   116941 acccaaattg ttaagggaat tgaggatatc gccagccaga atggctacca ggtaatgata
   117001 ggaaatagta actacagcca agagagtgag gacaggtata ttgaaagcat gcttctcttg
   117061 ggagtagacg gctttattat tcagcctacc tctaatttcc gaaaatattc tcgtatcatc
   117121 gatgagaaaa agaagaaaat ggtctttttt gatagtcggc tctatgaaca ccggactagc
   117181 tgggtcaaaa ccaataacta tgatgccgtt tatgatatga cccagtcctg tatcgaaaaa
   117241 ggttatgagc attttctctt gattacagcg gatacgagtc gtttgagtac tcggattgag
   117301 cgggcaagtg gttttgtgga tgctttaaca gatgctaata tgcgccacgc taggctaacc
   117361 attgaagata agcatacgaa tttggaacaa attaaggaat ttttacaaaa agaaatcaat
   117421 cccgatgaaa aaactctggt atttgttcct aactgttggg ccctacctcc agtctttacc
   117481 gttatcaaag agttgaatta taacttgcca caagttgggt tgattggttt tgacaatacg
   117541 gagtggactt gcttttcttc tccaagtgtt tcgacgttgg ttcagcccgc ctttgaagaa
   117601 ggacaacagg ctacaaagat tttgattgac cagattgaag gcctcaatca agaagaaagg
   117661 caacaagtct tggattgtag tgtgagttgg aaagagtcga ctttctaaga tgaaagggaa
   117721 ataactggca acctctgtta agaaataaaa taatcccatc tagcatgaac tggatgggat
   117781 tatttgtcta taaaatgaga aattacggga gtaatctcct aaatcaactg tttttgattt
   117841 acttctttaa ctacttgata aaagttatag aagtagacca aacttgagat gatggttacg
   117901 actaggaata ttggaaattt ccattggatg gagtttcttg attgtcttgg ttcaagactg
   117961 aaaaatcgta tagtgcagtc attgcttgct tttctccttc tgtttggtat ttttaggaat
   118021 tttctcctcc tgtagtgata gaaatccgta ggtcagggtt ccaaaaatgc tgccgataat
   118081 caggccgtac attaggaaag gaacactttt gtcgaattgc atgagcaact tcacaaaatc
   118141 tgaaagggac atctgctgaa cgaagacttt atgaaagatg agtaaggtaa agaggccaat
   118201 ctgaagaccg ataaacacaa tccaacttcg gaatttgatt tgggctttgc tgtaggtttt
   118261 gaggatgatt tctgacttgt catctttttc catatggagt tctttgacga ctctttgagt
   118321 ttttaaggta atgaaaaaaa tgagtccaga gtaaacgtag ggcatggcat agcgaacggc
   118381 ctctatgaag cgtccaaata atagataaaa caagaagagg aagaaggaag aataaacgat
   118441 ttggaccatg gaacgggcac aagctttgta gataatctct tgtcggcatt catcaaaagg
   118501 gccttggata tgaaagagat ttcggagtag gcgagtggtt aagtcttctt ttttcatgtt
   118561 agtaacctcc taaatgagcg gttttactga ttttctttta cgaattgata gagataataa
   118621 agataaatga tagaagaaag gctagcgata gtcagcagta aataataatt ccaattgcct
   118681 gagacgagca tcagttgtgg aaaagataga atcataaagt atagtgctaa gttaagtgtg
   118741 cgcgtttttg gggagtcaat ctttagataa gtcagtactt tgttaagggc tggaacaaag
   118801 actagcacga ggaatatctc tctgattaag ttccctgaaa cgatgatgaa gatgagcaga
   118861 gaactgaaca aaagatgata ggtaagtaaa gttagtaatg atttcatagg gcacctctta
   118921 atcctggtct tttttagctc ttgcaatacg aagtgagtcg acaatatgta tcatcactcc
   118981 gaaaaagaaa gctcccagta tagttttaaa aatatgtttt gtatttagaa gagaactgat
   119041 aaaatttgga ttttcacttg ttagggtatc aatgagtgga attataaaca atatcactgt
   119101 tccataaatc gaacctgctt tcagaccagg ataacgtaac tgtttctttt cttttttcat
   119161 gagtttcctc ctaatcatta tcctgatttt tcctggcttt tgcaatgcga cgggagatga
   119221 gaatctgtat aaccactcca aagaagacag actggaggat acttgaaaaa atatttttaa
   119281 aagcgagaag tgactgaaga tagtcctgac tctcacctag cagtatatgg agaagagggg
   119341 ttgtaaaaaa actcattaat ccatagacta tcccagcttt cagacctggg taatgtagtt
   119401 gcttactttc tttctcattc agcatatctg gttcaatagt tgtaatccct gttttttgca
   119461 tttggtaggt gagatatcca gcaacgatga gggcaatcac taaaattaga ggaggataga
   119521 ctagagccac tagttgagga tatttatagg ccagaaggag tggaataaga ttgccgaaaa
   119581 tcatcagata aaagaggaag ataaagactt gattgccgat acgatcagcc tcgcgtcgtt
   119641 tgtattcgtc aagtggatca gaaataccgt atgtgcgctt gatcagtttt tcagtgaagg
   119701 tttctttttt catgagttgg ctcctaatcc tcatcttgat ctttcttagt ttttgcaatg
   119761 cgacgggaga tgaggaactg tatgctcgct ccgaagaaaa tagaaccgag aatgcttgat
   119821 acaccatttc ttatagtgag gagagaatga aaatagtcct gaccttcacc tatgagtata
   119881 ctgagaagag gagttataaa aaacatccat agaccaaaga acaaacctgc tttaagacct
   119941 gggtaatgta gttgcttact ttctttctca ctcagcatat ctggatcaat agctgtaatc
   120001 cctgtttttt tcatttggta ggtgacatag ccagcagcga tgagggcaat cactaaaatc
   120061 agaggaggat agattagagc cacttcttga gggtatttat aggccagaag gagtggaata
   120121 agatttccga aaatcatcag ataaaagagg acgataaaga cttggttccc aatacgatcg
   120181 gcctcacgcc gtttgtattc gtcaagggga ccagaaatac cgtatgtgcg tttgatcagt
   120241 ttttcagtga aggtttcttt tttcataagt ttgctccttt tttaaaaatc ttcctcccaa
   120301 aagagactgt tgaggtcagt ttggaggctg cgggcgagat tgagacagag ttccagggtt
   120361 ggattgtact tgtcgttttc aatcatattg atggtctgtc tcgagacacc gatatccttg
   120421 gcgagctcga gctgggaaat gcccagttcc ttgcgaaatt ctttcacacg attcatctct
   120481 tctcctttct gatttgtgtc ggatatattt gactatatta tattcttcta tagagtgaat
   120541 gtcaagcata tttgacatat ttcttaaaga aatcttactt gggtttgctc tatttgtctg
   120601 actagtgcaa gctagtcgga tttgtggtaa aatagataag atatgacaaa agaatttcat
   120661 catgtaacgg tcttactcca cgaaacgatt gatatgctcg acgtaaagcc tgacggtatc
   120721 tacgttgatg cgactttggg tggagcgggc catagcgaat atttattaag caaattaagt
   120781 gaaaaaggcc atctctatgc ctttgaccag gaccagaatg ccattgacaa cgcacaaaaa
   120841 cgcttggcac cttacattga gaaggggatg gtgactttta tcaaggataa cttccgtcat
   120901 ttacaggcac gtttgcgcga agctggtgtt caggaaattg atggaatttg ttatgacttg
   120961 ggagtgtcta gtcctcaact agatcagcgt gagcgtggtt tttcttataa aaaggatgca
   121021 ccactggaca tgcggatgaa tcaggatgct agtctgacgg cctatgaagt ggtgaatcac
   121081 tatgactatc atgacttggt tcgtattttc ttcaagtatg gcgaggacaa attctctaaa
   121141 cagattgcgc gtaagattga acaagcacgt gaagtcaagc caatcgagac aacgactgag
   121201 ttggcggaga ttattaagtc ggctaagcct gccaaggagc tcaagaagaa gggccatcct
   121261 gccaagcaga tcttccaggc tattcgaatt gaagttaatg atgaactggg agcggcagat
   121321 gagtccatcc agcaggctat ggagatgttg gctctagatg gtagaatctc agtgattacc
   121381 ttccattcgc tagaagaccg cttgaccaag cagttgttta aggaagcttc aacagttgaa
   121441 gttccaaaag gcttgccctt catcccagat gatctcaagc ccaagatgga attggtatcc
   121501 cgtaagccaa tcttgccaag tgcagaagaa ttagaagcca ataaccgctc gcactcagct
   121561 aagttgcgcg tggccagaaa aattcacaag taagaggaaa aatgatggca gaaagaatgg
   121621 aaaaaacagg tcaaatacta cagatgcaac ttaaacggtt ttcgcgtgtg gaaaaagctt
   121681 tttacttttc cattgctgta accactctta ttgtagccat tagtattatt tttatgcaga
   121741 ccaagctctt gcaagtgcag aatgatttga caaaaatcaa tgcgcagata gaggaaaaga
   121801 agaccgaatt ggacgatgcc aagcaagagg tcaatgaact attacgtgca gaacgtttga
   121861 aagaaattgc caattcacac gatttgcaat taaacaatga aaatattcga atagcggagt
   121921 aagatatgaa gtggacaaaa aaagtaatcc gttatgcgac gaaaaatcgg aaatcgccgg
   121981 ctgaaaacag acgcagagtt ggaaaaagtc tgagtttatt atctgtcttt gtttttgccg
   122041 tttttttagt caattttgcg gtcattattg ggacgggcac tcgctttgga acagatttag
   122101 cgaaggaagc taagaaggtt catcaaacca cccgtacagt tcctgccaaa cgtgggacta
   122161 tttatgaccg aaatggagtc ccaattgctg aggatgcaac ctcctataat gtctatgcgg
   122221 ttattgatga gaactataag tcagcaacgg gtaagattct ttacgtagaa aaaacacaat
   122281 ttaacaaggt tgcagaggtc tttcataagt atctggacat ggaagaatcc tatgtaagag
   122341 agcaactctc gcaacctaat ctcaagcaag tttcctttgg agcaaagggc aatgggatta
   122401 cctatgccaa tatgatgtct atcaaaaaag agttggaaac tgcagaggtc aaggggattg
   122461 attttacaac cagtcccaat cgtagttacc caaacggaca atttgcttct agttttatcg
   122521 gactagctca gctccatgaa aatgaagatg gcagcaagag cttgctggga acctctggaa
   122581 tggagagttc cttgaacagt attcttgcag ggacagacgg cattattacc tatgaaaagg
   122641 atcgtctggg aaatattgtc cccggaacgg aacaagtttc ccaacaaact gtagatggca
   122701 aggatgttta tacgactatt tccagcaccc ttcagtcctt catggaaact cagatggatg
   122761 cctttctaga aaaagtaaaa ggtaagtata tgaccgcgac cttggtcagt gcaaagaccg
   122821 gtgaaattct cgctaccacc caacgaccta cctttaatgc agatactaaa gaaggaatca
   122881 ctgaggactt tgtttggcgt gatattcttt atcaaagtaa ctatgaacca ggatcagcca
   122941 tgaaggttat gacgttagct tcttctattg ataataatac cttcccaagt ggagaatact
   123001 tcaatagcag tgaattcaaa atagcggatg cgacgactcg agattgggat gttaatgatg
   123061 gtttgactac tggtgggatg atgactttct tacaaggttt cgctcactcc agtaatgttg
   123121 gaatgagtct acttgaacaa aaaatgggag atgctacttg gttggattat ctaaaacgct
   123181 ttaaatttgg ggttccaact cgctttggct tgacagatga atacgctggt caacttccag
   123241 ctgataatat tgttagtatt gctcaaagct catttgggca aggaatttca gtgacacaaa
   123301 cacaaatgct tcgtgccttt acagctattg ctaatgatgg agttatgctg gagccaaaat
   123361 ttataagtgc tatttatgat actaacaatc agtctgtacg taagtcacaa aaagaaatag
   123421 taggaaatcc tgtttccaaa gaggcagcaa gcacaactcg aaatcacatg atcttagttg
   123481 ggacggaccc tctatatgga actatgtata atcactacac aggaaagcca attataacag
   123541 ttcctggaca aaatgtagca gttaaatccg gtacggctca aatcgctgat gagaaaaatg
   123601 gaggatactt ggttggttct accaattata ttttctcagt tgtgactatg aatcctgctg
   123661 aaaatcctga ttttatcttg tatgtaacgg ttcaacagcc tgagcattat tcaggtatcc
   123721 agttgggaga atttgccacc ccaatcttgg agcgggcttc agctatgaaa gaatctctca
   123781 atcttcaatc tccagccaaa aatttagata aagttacgac agaatcttct tatgcaatgc
   123841 ctagcatcaa ggatatttca cctggtgagt tggcggaagc cttacgccga aatattgtgc
   123901 aaccaatcgt tgtaggtact ggaacaaaga ttaaagagac ttctgtagaa gaagggacca
   123961 atcttgcacc aaaccaacaa gttctccttt tatcggataa ggtagaagaa attccagaca
   124021 tgtatggctg gaaaaaagag actgccgaga cctttgctaa atggttggat attgaactgg
   124081 aatttgaagg ttcaggttcc gttgttcaga agcaagatgt tcggactaat acagctatca
   124141 aaaacattaa aaaaattaaa ttaactttag gagactaata tgtttatttc tattagtgct
   124201 ggaattgtga catttttact aactttagta ggaattccgg cctttatcca attttataga
   124261 aaggcgcaaa ttacaggcca gcagatgcat gaggatgtca aacagcacca ggcaaaagct
   124321 ggcacgccaa ctatgggggg acttgttttc ctcattgctg cagttgtggt gagtttcctt
   124381 cttgctcttt tttcaaaaca attgaccaat aatgtgggaa tgattttgtt catcttggta
   124441 ctttatggac ttgtcggatt tttagatgac tttctcaagg tctttcgtaa aatcaatgag
   124501 gggctgaatc ctaagcaaaa attggctctt cagctcctag gtggggtcgt tttctacctt
   124561 ttctatgagc gcggtggcga tatgctttct gtctttggtt accaagtgca tctagggatt
   124621 ttctatattg tcttcgctct tttctggcta gtcggttttt caaacgcagt caacttgaca
   124681 gacggtattg acggtctagc tagtatttcc gttgtgatta gtttgtcagc ttatggagtt
   124741 attgcctatg tgcaaggtca gatggatatt cttctagtga ttcttgccat gattggtggc
   124801 ttgctcggtt tctttgtctt taaccataag cctgccaagg tctttatggg agatgtggga
   124861 agtttggctc tcggtggaat gctggcagct atttcaatgg ctctccacca agaatggact
   124921 ctcttgatta tcggaattgt ttatgtattt gaaacaactt cggttatgat gcaagtaagt
   124981 tatttcaaaa tgactggtgg taaacgtatt ttccgtatga cgcctgtaca tcaccatttt
   125041 gagcttggag gattgtctgg taaaggaaat ccttggagcg agtggaaggt tgacttcttc
   125101 ttttggggag ttgggcttct agcaagtcta ctgaccctag caattttata tttgatgtaa
   125161 gaatggcacc ctgatgttca gtttcagggt gtttttgcat tctaaaaaac attggtcaat
   125221 taaagtcaaa actcttgacc ttttctgact aatgtagtat attataaacg taaggtaaat
   125281 gaaagcctta ctcgaacgct tatactcaat gaaaatcaac gagcaaatta ggaagtgctc
   125341 aaaacactgt tttgaggtta cagatagaac tgacgtggtt tgaagagatt ttcgaagagt
   125401 ataaaaacat tggtcaatca aagtcaaaat ccttgacctt ttctgaccaa tgtagtatat
   125461 tatgaacgta aggtaaatga aagccttact cgaacactta tactcaatga aaatcaacga
   125521 gcaaactagg aagctagacg caggttgctc aaaacactgt tttgaggttg cagatagagc
   125581 tgacgtggtt tgaagagatt ttcgaagagt attatttaaa gtaaaataga aagaggtggg
   125641 gtctatgttt aatctagaaa tcttcagaag taaagatagt ctactcctgc ttgaaaaaga
   125701 aaaaccagaa atagtaccta gagtagcgat ttagctaatc taaatttttt aaaacaaagg
   125761 tcaaagatag tcaatatcag taatcataac taagtaaata aaaagaggta aagaatatga
   125821 acaacaactt taataatttt aacaacatgg atgatttatt taaccaattg atgggtggta
   125881 tgcgaggata cagttctgaa aatcgccgtt acttgattaa tggacgtgaa gtaacacctg
   125941 aggaatttgc tcactatcgt gcaactggcc aattggcagg aaatgcagaa gttgatggaa
   126001 aaatgccaca acagccttca ggtatgaaac aagatggtgt ccttgcaaaa ctaggtcgta
   126061 acttgacagc agaagcgcgt gagggcaagc tggatcctgt tatcggacga aacaaggaaa
   126121 ttcaagaagc atctgaaatc ctctcacgcc gtaccaagaa caatcctgtt ttggtcgggg
   126181 atgcaggcgt tggtaagaca gcagttgtcg aaggcttggc acaagccatt gtgaacggag
   126241 atgttcctgc tgctattaag aataaggaaa ttatttccat tgacatctca ggtcttgagg
   126301 ctggtactca ataccgtggt agctttgaag aaaatgtgca aaatctagta aacgaagtaa
   126361 aagaagtagg aaatattatc ctcttctttg atgaaattca ccaaattctc ggtgctggat
   126421 ctactggagg tgacagtggt tctaaggggc ttgcggatat tctcaagcca gccctctctc
   126481 gtggagaatt gacagtgatt ggagcaacga ctcaagacga atatcgtaat accatcttga
   126541 aaaatgcagc tcttgctcgt cgtttcaacg aagtcaaggt caatgctcct tcagcagagg
   126601 atacttttaa aatccttcaa ggaattcgtg atctctatca acaacaccac aatgtcatct
   126661 tgccagacga agttttgaaa gcggcagtgg attattctgt tcagtatatt cctcaacgta
   126721 gcttgccaga taaggctatt gaccttgtcg atgtaacggc agctcacttg gcggctcaac
   126781 atcctgtaac agatgtgcat gctgttgaac gtgaaattga ggcagaaaaa gacaagcaag
   126841 aaaaagcagt tgaggcggaa gattttgaag cagctctcaa ctataaaaca cgcatcgcag
   126901 aattggaaaa gaaaatcgaa aaccacacag aagatatgaa agtgactgca agtgtcaacg
   126961 atgtggctga atctgtagaa cgaatgacgg gtattccagt gtcacaaatg ggagctacgg
   127021 acatcgaacg tttgaaagat atgggtcatc gtttgcagac gaaagttatt ggtcaagata
   127081 aggccgttga agcagtagca aaagctatcc gtcgtaatcg tgctggtttt gatgaaggta
   127141 atcgcccaat tggtagcttc ctctttgtag gaccaactgg ggttggtaag acggagcttg
   127201 ctaagcaatt ggcgcttgat atgtttggaa ccaaggatgc gattatccgt ttggatatgt
   127261 ctgaatacag tgaccgcaca gccgtttcta agctaatcgg tacaacagct ggttatgtgg
   127321 gttatgatga taatagcaat accttaacag aacgtgttcg tcgcaatcca tactctatca
   127381 ttctcttgga tgagattgaa aaggctgatc ctcaagtgat cactcttctc ctccaagtct
   127441 tggatgatgg tcgtttgaca gatggtcaag gaaatacggt gaacttcaag aacacagtca
   127501 ttatcgcgac ctcaaatgct ggatttggtt atgaagccaa cttgacagaa gatgcggata
   127561 aaccagaatt gatggaccgt ttgaaaccat tcttccgtcc agagttcctc aaccgcttta
   127621 acgcagttat cgagttctcg cacttgacga aggaagacct ttctaagatt gtggacttga
   127681 tgttggctga agtcaaccaa accttagcta agaaagagat tgatttggta gtcagtcaag
   127741 cggctaaaga ctatatcaca gaagaaggtt acgatgaagt catgggtgtt cgtccgctcc
   127801 gtcgcgtggt tgaacaagaa attcgtgata aagtgacaga cttccatttg gatcacctag
   127861 atgccaaaca tctggaagca gatatggaag atggcgtttt agtcattcgt gaaaaagcct
   127921 aatactcttc gaaaatcaaa ttcaaaccac gtcaacgtcg ccttgccgta ctcaagtaca
   127981 gcctgcggct agtttcctag tttgctcttt gattttcatt gagtataaga caaaattttg
   128041 agaataaaaa aagaaggagc cagctgaaaa aaactggttc ctttttttat gtttaaatca
   128101 catgacgctc aaaagcatca tctgaaatcc cttgttccaa gatgagtttt gcccattctt
   128161 tagcagaaaa gaggctgtgg tccttgtagt taccgcaaga ttcgatggtt gttccaggga
   128221 cgtcttccca agtagtagtt tcagcgattt ccttgagcga atccttgata acagctgcaa
   128281 tctcggcgct ggtatgacgc ccccacataa tcatgtggaa acctgtacgg caaccaaatg
   128341 gtgaacagtc aatcatgccg tcgatgcggg tacggatgag tttggctaag aggtgctcga
   128401 tagtgtgcag accagcggta gggattgagt cttcattggg ttgtactaag cgaatgtcat
   128461 aattggagat gatgtctcct tttggccctg tttcttcccc aatcaagcgg acatagggtg
   128521 ctttaacaat agtgtggtca agttcaaaac tttcaacaat aacttctttt gacatggtaa
   128581 atcctttcag ttttctaatt tcattataac ataaagccgg ctcctgagac agagagaaaa
   128641 cctctccgag ggtggagagg ttgaaatcgt tacttgcgat acaagcggtc gtattggtag
   128701 taagggtcaa aggttacatt gatacctagt ttgcgaagga cattcttgtc ttcatcggtt
   128761 aagatgatgg ttgagtgggc ttcgcttcct ttgaggttac caagctcttc catagcgcgg
   128821 gcagcatcag gattttctgt agctgtgata gcaagtgcaa tcaggatttc atttgaatgc
   128881 aggcgtggat tgcggctacc tagatgatcg attttaagac cttggatcgg tttgacaagt
   128941 tcaggttcga ttagttttac ttctttagca atgtcagctg atttcttgat agcgttgata
   129001 agagcagctg ctgtagggcc gaagagttcg gagttcttac ctgtgacgat ttctccgctt
   129061 ggtaattcaa gggctagggc tggtccgcca gtttcttctg ctttttgacg cgcaacgaca
   129121 gcaaccttgc ggtctgaagg tgtgataccg aggtcgttca taagcaactc aattttcttg
   129181 acagcagatt cgctaacttt ttcggctttg aaatcaagaa cagtctgata gtagcgacgg
   129241 atgatttctt gtttagaggc ttcgatagca gcctcattat ctgtaatagc gaaaccaacc
   129301 atgttgacac ccatgtctgt tggtgaagcg tatggagatt caccaaggat acgttctaac
   129361 atgcgtttga gaactgggaa aatttcaata tcacggttgt agttgacagt ggtttctcca
   129421 taggtttgaa gatggaaagg gtcaatcatg ttgacatcat caaggtcagc tgtggcagcc
   129481 tcgtaggcca aattgactgg gtgatgaagg ggaagattcc aaactgggaa ggtttcaaat
   129541 ttagcgtagc cagacttgat gccattgatt tggtcgtggt acatattgga catacaggtt
   129601 gccaattttc cagaaccagg tccaggagcg gttacgacaa tcaagttgcg actggtttta
   129661 atgtagtcat ttttccccat accttctggt gaaatgatgt gatccatatc tgtcggatat
   129721 cctttgattg gataatgaag ataagaatca attccgtttt tttcaagttg atttcggaag
   129781 gcatctgcag ctggttggcc agcgtactgt gtgatgacaa cggaaccaac aaaaatccct
   129841 aattcattaa atttgtcaat caaacgaaga acttcttggt cataagaaat gcccaagtca
   129901 ccacgtgctt tggaatgctc gatattactt gcattaatag caatcacaac ctcaacctgc
   129961 tctttcaatt cttgcaagag cttgattttg ttgtcaggct cataaccagg aaggacacga
   130021 gcagcatgga aatcttctaa cattttacca ccaaactcca agtagagctt gccgtcaaat
   130081 tgattaatgc gctccaagat gtggtcgcgt tgtagattca aatattgttc agaactaaaa
   130141 gcttgttttt tcattttttt acctctgacc tctattataa taaaaaattg gaagttagga
   130201 aactatggag tcaaaaaaga aattaaaaag attaggcaaa cgcttgcaca aaattctaaa
   130261 aagcgctatc atagactata gattattaaa ataatgaggt aagaagatgc aagaaaaatg
   130321 gtggcacaat gccgtagtct atcaagttta tcctaagagc tttatggata gcaacggaga
   130381 tggaattggt gatttgccag gtattaccag taagttagac tatctagcta agttaggaat
   130441 cacagcgatt tggctttctc ccgtttatga cagccctatg gatgataatg gctacgatat
   130501 tgctgattat caagcaattg cagctatttt cggaaccatg gaggatatgg accaactgat
   130561 cgcagaagcc aagaagcgtg atattcgtat catcatggac ttggtggtca atcatacctc
   130621 agatgaacat gcttggtttg tcgaggcctg tgaaaatcct gatagtcctg agagagacta
   130681 ctatatttgg cgggatgaac ccaatgattt ggattctatc tttagtggtt ctgcttggga
   130741 atacgatgaa aagtcaggtc aatattatct ccactttttc agtaagaaac agcccgatct
   130801 caactgggaa aatgaaaaac ttcgtcagaa aatttatgag atgatgaact tctggattga
   130861 taaaggcatt ggtggtttcc gcatggatgt cattgacatg attggcaaaa ttcctgacga
   130921 gaaagtagtc aataatggtc ctatgctcca tccctatctc aaggagatga atcaggcgac
   130981 ctttggagat aagaatctct tgacagtagg ggagacttgg ggagcaacgc cagcgattgc
   131041 caagctctac tcagatccaa aggggcaaga attgtctatg gtcttccagt tcgaacacat
   131101 cggtcttcag tatcaggaag ggcaacctaa atggcactat caaaaagagc tgaatatcgc
   131161 taagttaaaa gaaatcttca acaaatggca gacagagtta ggagttgagg acggttggaa
   131221 ttccctcttc tggaacaacc atgaccttcc tcgcatcgtc tcaatctggg gaaatgacca
   131281 agaataccgc gaaaaatctg ccaaagcctt tgcaatcttg cttcatctca tgagagggac
   131341 tccttatatc taccaaggtg aggagattgg gatgaccaac tatccctttg aaacactgga
   131401 ccaagtagaa gatattgaat ctcttaacta tgcgcgtgaa gctcttgaaa aaggtgtttc
   131461 gatggaagaa atcatggaca gtatccgtgt cattggtcgt gacaatgccc gtacccctat
   131521 gcaatgggac gagagcaaaa acgccggttt ctcgacaggt cagccttggt tggcagtcaa
   131581 tccaaactac gaagaaatca atgttcaaga agcactggca aatccagatt ctattttcta
   131641 tacttataaa aaactcgttc aaatccgcaa ggagaatagc tggctgattc gagctgactt
   131701 tgaattgctt gatacggctg acaaggtctt tgcttatatc cgtaaagatg gcgaccgtcg
   131761 ttttctagtt gtggccaact tgtccaatga agagcaagac ttaacagtag aaggaacagt
   131821 caaatctgtc ttgattgaaa acaccacggc tcaagaagtc tttgaaaaac aaatcttagc
   131881 tccatgggat gctttctgtg tggaattgac tgactaaaat gagagagagt gggcaaaaac
   131941 tcgacttcag gagaaaatga agtaaatctt tccacaataa aatgcatagt accaagtttt
   132001 ttcaagacct gatattatgc gttttttgtt ttaaagactt ttttcccagc ctctttttgc
   132061 taaaagttgt gtaaaaactc ttttaaaaac atttgttaga attttctaac aaattccata
   132121 agaactcttg catttataaa aaaatagggt ataatagtga aaatactatt ttgaaggaga
   132181 ttatttatgc aatcgaaaaa gtggctcata ggagcaggag tgaccttgag tacagccatt
   132241 cttttaacag cttgtgggaa aagtgaaaag aatgcagatg ctcccaaaac attttcttat
   132301 gtttatgcag ttgatccatc atccttggat tatagcctta caagtaaaag ttcaacttct
   132361 gacgtaatag gtaatgtcgt cgacggtctt ttagagaatg ataaatatgg gaatctcatt
   132421 ccttctctag cagaggattg gtcagtttct aaagatggtt tgacttatac ctacaaacta
   132481 cgtaaaggtg tgaagtggta tacttcagaa ggagaagagt atgcggaagt taaagctcag
   132541 gattttgtta caggtctgaa acatgcagca gatggaaagt ctgatggtct ttctttggtt
   132601 gagaaatcta tcaaaggatt ggaggcttat gttagtggtg agacaaacga cttctcaact
   132661 gtaggtgtga aggctcttga tgattatacg gtagaatata cccttaataa cccggaaagt
   132721 ttttggaact ctaaagtaac cacagcaacc atgcttcctg taaatgaaga atttttgaat
   132781 gcaacaggca aggattacgg agcgccaact ccatcaagta ttctttacaa tggcccatat
   132841 tttttgaaat ctttgatttc taaatctgtg attgaatatg aaaaaaatcc taactattgg
   132901 gataaggaca atgtcaaaat tgataatgtt aaattgacat tctatgatgg ttcagatcaa
   132961 gaatccttaa ttcgtagctt tacacaaggt gcctatacca ctgcacgtct ttttccagca
   133021 agctcaaact ttgagtcaac taagaaagag tacggagata agattgtcta tagtccacaa
   133081 gaggcaacaa gctactacct cactgtgaat gtaaaccgcc agtcttacaa taaaacagct
   133141 aaaacagatg agtcacaaaa aacatcaaca aaagaagctc ttctcaataa gaacttccgt
   133201 caggctctta attttgcatt taatcgccac gcctatacag ctcaattaaa cggtgaagag
   133261 ggtgcggata agattattcg taatagtcta gtgccagata attacgttca agtagctggg
   133321 aagaccttcg gacagttggc tcaggatgaa ctactgaaat atggagaaca gtggaaagat
   133381 gtgactctca cagatggtaa ggatacaatt tacaatccaa caaaggccaa gtctgcattt
   133441 gaaaaagcga agtcagaatt gcaagctaag ggagtgagtt tcccgattca tctggatgtg
   133501 cctgttgagc aaactgatgt agttgcggtt caacaaacca attcgctaaa acaatcaatt
   133561 gaagaaacgc ttggaacgga gaatgtcatt atagatgttc ttcaaatgac agataatgag
   133621 aaggaaagta ttacttctca agctaaagtt ccaacccaaa aagattatga tttgaacgga
   133681 acaggttggg gaccagatta ccaagatcca gcaacctatc tcaatatttt agatgctaag
   133741 aagggttctg ccttgaaaca tctaggtata acaaagggca aggatcctga agttgtggcg
   133801 aaagttggct tggatgaata caagaagctc ttggatgatg cggcttctga gacaagtaat
   133861 cttgataaac gatacgaaaa gtatgccaaa gcacaggctt gggttactga tagttcactt
   133921 cttattccag ttgcttcttc agggggctct cctatggtta gtcgtactgt tccatttacc
   133981 aaagcttatt cacaggtcgg tattaagggg gatccattta tttttaaagg aatggaactt
   134041 caaaatgata ttgtgacaac taaagagtat gatgcggcct tcaaaaagtg gcaaaaggaa
   134101 aaactggaat cgaatgctca gtatcaaaag gatttagaaa agcacataaa ataatgagaa
   134161 tgagaatctt gctttcgtta ggttatcagt taattcattg atattcaaat gataaatcgt
   134221 ataaaaacaa gggaggattg tatgaaaagc agaaatcctt tgttttttta taaccaaagt
   134281 ttataaactt tggttataaa aattcaatta actttacaaa ttcccactat tttggtaaaa
   134341 taaatatatg ttataaaaac taacataaag gagaaagaag atgactacaa aaaagcgtat
   134401 ccttagtgca ggactgactt ttgcagctgc tttgctttta gctgcttgcg gacaatcagg
   134461 ttcagataca aaaacttact catcaacctt tagtggaaat ccaactacat ttaactatct
   134521 attagactac tacgctgata atacagccat cattaccaac ctagttgatg gtttgcttga
   134581 aaatgacaac cacggaaacc tagttccatc tttggcagaa gactggtctg tttcaagcga
   134641 cggtctgact tatacctaca aattgagaaa agatgccaaa tggttcacag ctgacggtga
   134701 agagtacgcc ccagtcaagg ctcaggattt tgtgacaggt atcaagtatg cagtggataa
   134761 taaatcacag gccattgact tgattcaaaa ctcgatcaag ggcttgaatg attatattac
   134821 aggagcggat tctgactttt ctaaggttgg ggtgaaggcc attgacgacc agactgtcga
   134881 gtatactttg acacgcccag aaccttactg gaattcaaaa acaaccaata gtattctttt
   134941 cccagtaaac gaagagtttt taaactcaaa agggaaagat tttgggaccc tatctccaga
   135001 tagcattctc tacagcggac cttatttgtt aaaagatttc acatcaaaat catcaatcga
   135061 gtatgtgaaa aatccgcatt actatgatca tgacaaagta tcaattgaac atgtgaaatt
   135121 ggcttatttt gatggctcag accaagaatt gaccatccgt aactttgaaa gtggagctta
   135181 ttcaatcgct ggggtttatc caaatagttc aaactttgct aagactaagg aaaaatataa
   135241 ggataatatc gtctatagct tgcaggacaa gacttcttgg tacttcaatt ttaacgtcaa
   135301 ccgtaaggca tacaaccata catctaaaac gacagatgag cagaagaagt caactgagac
   135361 agctgtcttg aacaagaact tccgccaagc agtgaacttt gccttggacc gcacagccta
   135421 ttctgcccag tcaaatggag aagaggcggc tagcaagacc cttcggaaca ccttggtgcc
   135481 tcctacattt gtccaagttg gagacaagac ctttggagaa gtagtcgctt ctaaattggt
   135541 caactatggc acagaatggt caggtattaa cttggcagat gctcaggatg cctatttcaa
   135601 caaagaaaaa gcccaagcaa aatttgtgga agctaaaaaa gaattggcaa gtcaaggtgt
   135661 gactttccct attcacttgg atgtggcggt tgatcagaca agtaaaaatg ccgtgacagg
   135721 tatgaactca gttaagcaga cccttgagtc agttttaggt gctgataacg ttgtcattga
   135781 tgttcagcaa ctttcaacag atgattttaa taatgtagcc ttcttagcgc caacagcagc
   135841 tgatcgtgac tatgatttga actttgatgg ctgggtaggt gactaccaag atccatcaac
   135901 ttatctcaat cctttcaatg cagaggatgg cttctacctt aagatttttg gactagatgc
   135961 caaggaagac aaggaaaaaa tcactagtct aggtctggat acctacacta agatgctcaa
   136021 agatgcagat agtgaaaaca aagatgtagc taaacgttac gaaaaatatg ctgaagcaca
   136081 ggcttggatg attgacaatt ctctgattat gtcagctatg tcaagtggtg gaacagcatc
   136141 tgtaaccaaa gtaacgccat ttacaagagg ctattcgttg gttggtatca agggtgatgg
   136201 caataactac aagtacatga aactgcaaaa agacactgtt acaactaaac agtttgaaga
   136261 agctaagacc aaatgggagc aagaaagcaa aaaagcaatc gaaaaagccc aaaaagaagc
   136321 agaaaaacat gttaaatagt tagaaatagc cttttcaagc aaaatcctaa agacaaacat
   136381 cagttttggt gcttgtcttt ttaaatcact cggctattga aaactgagaa atgatttgtt
   136441 ttgtgctaaa atagattgaa acgaatactc aataaaaatc aaagagtaac tgggaagtta
   136501 gctcaaagta cagctttgag gtggtagata gaactgacga agtcagttca aaatactgtt
   136561 ttgaggttgc agatggacgc tgacgtgctt tgaagagatt ttcgaagagt ataaagatcc
   136621 tctcttttgc tatagttaag gagatgagag gtaaatgata aggaagagac tatgtacgac
   136681 tatctaatcg ttggtgctgg tttgtcggga gcaatttttg cttatgaagc aaccaagcgt
   136741 ggaaaaaaag taaaagttat tgataaacgt gaccacattg gtggaaatat ctactgtgag
   136801 aatgtagaag gggttaatgt tcataaatat ggtgcccata tctttcatac ttctaataaa
   136861 aaagtttggg attatgttaa tcaatttgct gaatttaaca actacatcaa ctcgcctgta
   136921 gctaattaca agggtagcct ttataatcta cctttcaata tgaatacttt ctatgctatg
   136981 tgggagacaa aaactcctca agaagtgaaa gataagattg ctgagcaaac ggctcacatg
   137041 aaggacgttg aacctaaaaa tttggaagaa caggctatca agttgatcgg tccagatatt
   137101 tatgaaaaat tgattaaagg atatactgaa aagcaatggg gacgttctgc gactgacctt
   137161 ccacccttta tcatcaaacg tctaccagtt cgtttgactt ttgataataa ctacttcaat
   137221 gaccgttacc agggtattcc aattggcggt tacaacgtca tcatcgaaaa tatgctcaag
   137281 gatgtggaag tagaacttgg tcttgacttt tttgccaatc gtcaggaatt agaagcttct
   137341 gctgaaaagg ttgtctttac agggatgatt gaccaatact tcgattataa acatggtgag
   137401 ttagaatatc gtagtcttcg ttttgagcat gaagttctca atgaagaaaa ctatcaagga
   137461 aacgcagttg tcaactatac agaacgagaa attccttata ctcgcattat tgagcataaa
   137521 cactttgagt atggtacaca agctaaaacg gtcattactc gtgaataccc agctgattgg
   137581 aaacgaggag atgaacctta ttatccaatc aatgatgaga gaaacaatgc tatttttgcc
   137641 aaatatcagg aagaagcggc aacaaatgac aaggttattt tctgtggtcg tttagcagat
   137701 tataaatact atgacatgca tgtggtcatt gaacgggctt tggaagtagt cgcggaagag
   137761 ttgggacaat aatgcaagga ttctgtcatt ttagaatctt tgctacttaa gatttttaga
   137821 agtaaggtca acaagattct tttctgctta tcagaagaga acttctgttg gctttttttt
   137881 ggcataaatg aacaatttta tttttcagaa tatatcaaat ataacaaata actcttaaaa
   137941 ttcagaaaat tctattgaca ggacttgaaa aagagtctat aatgaataaa aaaacaaagg
   138001 agaagactat gaaaacaaga aaagtattgg ctcttgcggg agtaacctta ttagcagctg
   138061 gtgttttagc tgcttgttct gggggttcag gtgctcaagg tgaaaaaacc tttgccttta
   138121 cctacgagac acatccagat aatctcaact atttgacaac tggtaaggca gcaacttctg
   138181 agattactag taatgtgatc gatggattac ttgaaaatga taaatacggg aaccttattc
   138241 cctcaatggc agaagactgg tcggtctcta aggatggctt gacttatact tataagattc
   138301 gtcaggatgc caagtggtat acatctgagg gagaagagta cgctcctgtt aaggctcagg
   138361 actttgtaac aggacttaaa tatgcaacag ataagaaagc agaagccctt tacttggtac
   138421 aggattcaat caaaggtctg gatgcctatg ccaaaggtga aatcacagac tttgctcaag
   138481 tcgggattaa agcccttgac gatcagacag tccaatacac cttgaacaaa cctgaaactt
   138541 tttggaattc taaaacaacc atgggtgtgc ttgcgccagt caatgaagag tttttgaatt
   138601 caaaagggga tgattttgcc aaagctacgg atccaagtag tctcttgtat aacggccctt
   138661 atttgttgaa atccattgta actaaatcct ctgttgaatt tgcgaaaaat ccgaactact
   138721 gggataaaga caatgtgcat attgacaagg tcaaattgtc attctgggat gggcaagata
   138781 ccagcaaacc agcagaaaac tttaaagatg gtagccttac agcagctcgt ctttatccaa
   138841 caagtgcaag tttcgcagag cttgagaaga gtatgaaaga caatatcgtc tatactcaac
   138901 aagactctac gacttattta gtaggaacaa atattgaccg tcaatcttat aaacacacat
   138961 ctaagactag cgacgaacaa aagacatcta ctaaaaaagc tctcttaaac aaggatttcc
   139021 gtcaggctat tgcctttggt tttgaccgta cagcttatgc ttctcagttg aatggagaaa
   139081 ctggagcaag caaaatcttg cgtaatctct ttgtgccacc aacatttgtt caagcagatg
   139141 ggaagaactt tggcgatata gtcaaagaaa aattagtgac ttatggggat gaatggaagg
   139201 atgtcaatct tgcagattca caagatggtc tttacaatcc agaaaaagct aaagcagaat
   139261 ttgccaaagc caaatcagcc ctacaagctg agggagtaca attcccaatt cacctagata
   139321 tgcctgttga ccagacagca actacaaaag ttcaacgtgt ccaatctatg aaacaatcct
   139381 tggaagcaac tttaggaact gataatgtcg ttattgatat ccaacaattg caaaaagatg
   139441 aattgcttaa tgtaactcta tttgccgaaa atgctgctgg cgaagactgg gatttatcag
   139501 ataatgtcgg ttggggtcca gactttgccg atccatcaac ctaccttgat attatcaaac
   139561 cttctgtagg agaaagtact aaaacatatt taggatttga ctcaggggaa gataatgtag
   139621 ctgctaaaaa agtaggtcta tatgactacg aaaaattggt tactgaagct ggtgatgaga
   139681 ctacagatgt tgctaaacga tatgataaat acgcagcagc ccaagcttgg ttgacagata
   139741 gtgccttgat catcccaaca acttctaaaa ctggtcgtcc aatcttgtct aagatggtac
   139801 catttacaat accatttgca ttgtcaggaa ataaaggtac aagtgaccca gtcttgtata
   139861 aataccttga acttcaagac aaggcagtta ctgcagatga atatcaaaaa gctcaagaaa
   139921 aatggatgaa agaaaaagca gaatccaata aaaaagcgca agaagaactc gcaaaacatg
   139981 tgaaataaga taaaaagaga ctgagcaaaa agtctttaaa agcaaaacgc atattgtcag
   140041 gtgatgaaag ccttgatcgt atgcgtttta ttgtggggaa atgtacttga tctctgtatt
   140101 tcattttgaa aatgacaaaa tcctgagttt agagttctca ggattttttc gtttactgtt
   140161 gtggttgctg ttgaacttgt ggattttgtg gcgttggttg tactggttgt gtcggttgaa
   140221 cagcttgtcc ttgattagga tcagttgctg gagcattatt gggttgttga ccaaccgtag
   140281 tacttgcctg tgtagttgaa ctttcagctg ttgaggattg ttgagtagag ggttcagtcc
   140341 atattgggcg agctccattt ttgaatacaa attccccgtt tctgaaaagt ccgtctggca
   140401 tcgtccagtc ttctggatga gtatcttctg atagatacgt tatcattgag cgataaactt
   140461 tagctgcaac taggaaacca tctccaacga taggagttaa acgattcgaa taacctgtcc
   140521 atacagccat agaatactta cgagtataac caacaaacat ttcatctgga gctacatagc
   140581 cagtgttctt gatgtgtttt tcaatttcat catctgtgta gttagaagta cctgtcttac
   140641 cagcttgcgc taaccatggg agataggctc cacgaccagt tccgtatgcc aagacagttt
   140701 tcatcatttc ggtcatcatg taagcagttg tttctttcat agctcgtgta cctacatctg
   140761 aaaattcttt ttcactaccg tcactgaaga cgaccttatt gatatacatg ggtttgtggt
   140821 aaattccacc gttggcaaag gcagcataag cagcagccat tttttcacta cttgctccgt
   140881 attgtttatt agattctgtt gtattacttg aaatggcgtt tgcataatgc atgcttggat
   140941 agtcgatacc aagaccatta aggaaggttt tagctctatc tagaccgacc ttattcaaag
   141001 tctcaacggc tgtgacattt cgtgattgtt gaagagcata ttgcagagta atattaccga
   141061 aatatgctct atcccagttg tagacaggtg tgcttgttcc cggatagtta taaggaatat
   141121 cattaaccat agttgcagtg gaatcataaa caccgtattc tatggcaggt gcataatcgg
   141181 tgattggttt catagcagaa ccccagtcac gattggtttc cacagcttgg ttggtaccaa
   141241 atgaaacgtt acttgcttgg tgacgagctc caagttgggc gatgacttta ccatttgaaa
   141301 catctacgac cgtagatgcg acttgcaaat catcgtcagg gtaagagacg tattgatcgg
   141361 agttgtagat atcccacaga tgtttttgag cttcttggtc tacatttgtg taaacatcca
   141421 tcccagtagt tagaaggtta tagccagttt cttgttctac ttgattgatg acctccttga
   141481 ggtaattatc catgtaagca gggtaattac ttgctgattt gagactttgt agtccatcag
   141541 taattggtgt attgactgct ttctcatact gttcagcaga gatgtaacct tgatttttca
   141601 tttcagataa gaccaagttt cggcggtctt gggctgcttc tggatgtgaa taggggtcat
   141661 attggtttgg tgcctgaggc attccagcca gcaaggctaa ctgaggtaaa cttaaattat
   141721 tgaggtcttt accatagtag ttttgagctg ctgtctgcat tccatagttg ccattagaca
   141781 tgtagacctt atttatatag taggtcaaga tttcctgttt ggttgctttt tgttctaact
   141841 gaatcgctaa ccaagcttcc tgagccttac gagaaatagt ctggtcggaa gtcgaggttg
   141901 aaaagtaagt caacttaatc aactgttggg tgagagttga tccaccttgg agggaattac
   141961 tttgcagatt gcgcaagaaa gctcccagga tacggatgga atcaatcccc ctgtggtcga
   142021 agaagcgatg gtcttcgata gaaacgattg ccttaaccaa atctgtggga atatcattag
   142081 cttgggcatt gacgcggcgt tcagaaccca agtcagcaat gagttgattt ttattgtcgt
   142141 agattttact agaagttgtt gcaactagtt tactctcgga taggctagga gccttgctaa
   142201 cgtagtagaa aaaaactcct ccgcctaaga caatggctgc gataaccaag cttaagaagc
   142261 taatgctcag atacttgatt aggcgcagaa tcgttggttt gttcatcttg ttttaccacc
   142321 taataaatgt tctttgataa cattgagata aggaatttga gggaaggcac cagccttgat
   142381 ttcatatcca tattctcgaa tatatccaag tggcattgat ttttgtccct tatcttgatg
   142441 atagaagcga atcaaatcga atgccggcaa taagtaggtt tcttgctgag aagaaaagtg
   142501 aagaaggaca aagcagattc cttgttgggc aaggacttgt tccatatgct gaatctgatg
   142561 tggatgaaaa tttttcatcg gaatcgcacg tttttgtttt gtttccttgg cttcaaagtc
   142621 gatgtaatat ccattataaa cgccagaata gtccgtcgtt gaagcttgtc gaaaataggc
   142681 ctcaacaatc ttggcacgac ttcgttgtgg atagtccact cgtacgattt gaataggagt
   142741 tggtttcttg tgtataacag ccaagccctg agacaaatag tagtcgttgg tagcattgat
   142801 catcttttca aaagacattc ctcgatttgc gaaatttttg ggttgagaaa gagaggtttg
   142861 tcttttttgt gatgaaagtt tatgtggata gttgaccata attctcctta ttggtacaat
   142921 aacatcactc tattatacca taaatttgca cagaaagggt taaaaatggc tacagctttg
   142981 gttttaggct attctgcttt tgatttgggt ttattttctg acaaggatcc tcgtcttaaa
   143041 ttgataaaaa aagcaatacg taaagattta gaggctatgg cagcagatgg ggtgtcttgg
   143101 cttgtgttta caggaagttt gggttttgaa tattgggttt tagaggttgc tcaggaaatg
   143161 aagaccgaat acggtttcca gttggcgacc atttttgctt ttgaaaccca tggggaaaat
   143221 tggaatgaag gcaatcagat gaaactgagt cgttttaagc aggtagactt tgtcaaatat
   143281 gcttatcctc gctatgaaca caaggggcag ttaagagatt accagcagtt tttgctggaa
   143341 aatacgacta gttcctatct tttttatgat gaagaaaatg agacgaaact agcttatttt
   143401 taccaaaaga tgaaaaatca agaggactat tttataaaga gattaacatt tgatcaatta
   143461 aatgaacttg ctgaaaattt ttccgaaaat tgaagctttg accttgattt ttgtttgcct
   143521 ttttttatat aataatacta gcaagcgaga atggagagag acatggcaag tattattttt
   143581 tcagcgaaag atatttttga acaagagttt gggcgtgaag tccgtgggta tagcaaggta
   143641 gaagttgatg agtttttaga cgatgtcatc aaggactatg aaacctatgc tgccttggtc
   143701 aagtcacttc gtcaggagat tgcggatttg aaggaagaat taactcgtaa accgcaagtg
   143761 agttcggctc caagtcctag tcacccagat ccaattgatg tggctgcttc atcttctatg
   143821 acgaattttg atattttgaa acgcttgaat cgtcttgaaa aagaagtatt cggtaaacaa
   143881 attttagaca atactgattt gtaattcagg tcttgttaca tgcaattttt ggataatcgc
   143941 gtgaggagag ttgcttctca tgaggaaagt ccatgctagc acaggctgag atgcctgtag
   144001 tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc agttgaaatg
   144061 gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg agtctttctg
   144121 gaaacaggga gagtggaacg cggtaaaccc ctcaagctag caacccaaat tttggtcggg
   144181 gcatggagta cgcggaaacg aacgtagtat tctgactgct atcagctaga gctgttagtg
   144241 gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa acatggctta
   144301 tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt ttaaagtgga
   144361 catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta attgcaactg
   144421 tggcagcagg gcttgaagct gttgtaggac gagaagtacg agagctgggc tacgattgtc
   144481 aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc gaaaccaacc
   144541 tctggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aactttccca gctaagactt
   144601 ttgaagagct gtttcaggga gttttcgctt tagattggga aaattattta ccactcggag
   144661 ctaggttccc aatttcgaaa gcaaaatgtg ttaaatctaa actgcataat gaacccagtg
   144721 ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat gctcgcccag
   144781 aaggtgttcc tctgatggag aatggtccag agtttaagat tgaggtctct attctcaaag
   144841 atgtggcaac tgtcatgatt gatacgacag gctccagtct ctttaagcgt ggctatcgta
   144901 ccgaaaaagg cggcgctcct atcaaggaaa acatggcggc agctatttta caactttcta
   144961 actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact ttctgtatcg
   145021 aggctgtcat gattgctcga aagatggcac caggacttcg tcgctctttt gcttttgaag
   145081 aatggaactg ggtcagcgat cgcttgattc aagaagtgcg tacagaagca gctaaaaaag
   145141 tggatcgtga gctggagctg gatatcatgg gctgtgatat cgatgcacgc atggtggaaa
   145201 ttgctaaggc caatgcccag gcagttggtg ttgcaggaga cattactttt aagcagatgc
   145261 gcgtgcagga tttgcgttcc gataaaatca atggtgtgat tatttccaat ccgccttacg
   145321 gggagcgttt atcagatgat gcaggggtga ccaagctcta tgctgagatg ggtcaagtat
   145381 ttgcaccact gaaaacttgg agtaagttta tcctaactag tgatgaagca tttgaaagta
   145441 agtatggtag tcaggcggat aagaaacgta agttatacaa cggaaccttg aaagtggatc
   145501 tgtatcaata ttttggtcag cgtgttaaac gccaagaggt aaaatagaaa gggatactca
   145561 tgagtaagaa aagacggaat cgtcataaaa aagaaaacca agaatcgcga tttgattttg
   145621 atgaagcaaa agagttaaca gttggtcaag ctattcgtaa aaatgaagaa gtggaagcag
   145681 gagtcttgcc tgaagattcc attttggaca agtatgtcaa gcaacacaaa gatgaaatcg
   145741 aagcagataa gtttgcgact cgccaataca aaaaggagga gttagtcgaa actcagagtc
   145801 tggatgattt aattcaagag atgcgtgagg ctgtagaaga gtcagaagct tcttcggagg
   145861 aagttccatc ttctgaagac atcttaccac ccttgcctct ggacgatgag gagcaaggct
   145921 tggattctct attgctagag gatgaaaatc caacagaaat gactgaagaa gtggaagagg
   145981 agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa aaaggctttg
   146041 ttttgaccgc tttggcgctt gtatcagtga ttatctgtgt cagtgcttac tatgtttacc
   146101 gtcaagtgaa tcgctcgacc aaggaaattc aaacttctca atcagctaca gccaatcaat
   146161 cagatgtgga tgattttaat acactttatg acgccttcta cacagatagc aataaaacgg
   146221 ctttgaaaaa tagccagttt gataaactga gtcaactcaa gaccttactt gataagctgg
   146281 aaggtagtcg tgaacatacg cttgccaaat cgaagtatga tagtctagca acgcaaatca
   146341 aggctattca agatgtcaat gctcaatttg aaaaaccagc tattgttgat ggtgtgttgg
   146401 acactaacgc taaagctaaa tcggatgcta aatttacaga tattaaaact ggcaatacgg
   146461 agcttgataa agtgctagat aaggctatca gccttggtaa gagccagcaa acaagtactt
   146521 ctagctcaag ttcaagtgaa actagtagct caagctcaag tcaagccagc tcaaatacga
   146581 ctagtgagac aagcccaagt agttcaaatg ctgcctcaaa tgagactaga agttctcgta
   146641 gcgaagtcaa tatgggcgta tcaagtgcag gggttgctgt tcaaagaagt gctagtcgtg
   146701 ttgcctataa tcagtctgct attgatgata gtaacaactc tgcttgggat tttgcggatg
   146761 gtgtcttgga acaaattcta gcgacttcac gttcacgtgg ctatatcact ggagaccaat
   146821 atatccttga acgtgtcaat atcgttaatg gcaatggtta ttacaacctc tacaagccag
   146881 atggaaccta tctctttacc cttaactgta agacaggcta ctttgtcgga aatggcgctg
   146941 gtcatgcgga tgacttggac tactaagcag tcgttacaaa attctttctt ttcaaaagta
   147001 aaaatgataa aataaaacaa atcaaacaag aggagtgtca aatgacaaaa gctaactttg
   147061 gtgtcgtagg tatggccgta atgggtcgta accttgccct taatattgaa tctcgtggtt
   147121 acacagttgc tatttacaac cgtagtaaag aaaaaacgga agatgtaatt gcttgccatc
   147181 ctgaaaagaa ctttgtacca agctatgatg ttgaaagttt tgtaaactca atcgaaaaac
   147241 ctcgccgtat catgctcatg gttcaagctg gacctggtac agatgctaca attcaagccc
   147301 ttcttccaca ccttgacaag ggtgatatct tgatcgacgg aggaaacact ttctacaaag
   147361 atacaatccg tcgtaatgaa gaattggcaa actcaggcat caactttatc ggtactgggg
   147421 tttctggtgg tgaaaaaggt gcccttgaag gtccttctat catgcctggt ggacaaaaag
   147481 aagcctacga attggttgcg gatgttcttg aagaaatctc agctaaagca ccagaagatg
   147541 gcaaaccatg tgtgacttac atcggtcctg atggagctgg tcactatgtg aaaatggttc
   147601 acaacggtat cgagtatggt gatatgcaat tgatcgcaga aagctatgac ttgatgcaac
   147661 acttgttagg tctttcagca gaagatatgg ctgaaatctt tactgagtgg aacaagggtg
   147721 aattggacag ctacttgatt gaaatcacag ctgatatctt gaaccgtaaa gacgatgaag
   147781 gccaagatgg accaatcgta gactacatcc ttgatgctgc aggtaacaag ggaactggta
   147841 aatggactag tcaatcatca cttgaccttg gtgtgccatt gtcactcatc actgagtcag
   147901 tatttgcacg ttacatttca acttacaaag aagaacgtgt acatgctagc aaggttcttc
   147961 caaaaccagc tgacttcaaa tttgaaggag acaaggctga gttgattgaa aagatccgtc
   148021 aagcccttta cttctcaaaa atcatttcat atgcacaagg ttttgctcaa ttgcgtgtag
   148081 cttctaaaga aaacaactgg aacttgccat ttgcggacat cgcatctatc tggcgtgatg
   148141 gctgtatcat ccgttctcgt ttcttgcaaa agattacaga tgcttacaac cgtgatgcag
   148201 accttgccaa ccttcttttg gatgagtact tcttggatgt tactgctaag taccaacaag
   148261 cagtgcgtga catcgtagct cttgctgttc aagctggtgt accagtccca actttctcag
   148321 cagctattac ttactttgat agctaccgtt cagctgacct tccagctaac ttgatccaag
   148381 cgcaacgtga ctactttggt gcccacactt accaacgtaa agacaaagaa ggaacattcc
   148441 actactcttg gtatgacgaa aaataagtag gtctgccatg gggaaacgga ttttattact
   148501 tgagaaagaa cgaaatctag ctcatttttt aagtttggaa ctccaaaaag agcaataccg
   148561 agttgatcag gttgaggagg ggcaaaaagc cctctccgtg gctcttcaga cagactatga
   148621 cttgatttta ttgaatgctc atctggggga tatgacagca caggattttg cagacaagct
   148681 gagtcggact aagccagctt cagtcatcat ggtcttggac catcgcgaag aattgcaaga
   148741 agagctggaa gttgttcagc gttttgcagt ttcatacatc tataagccag tccttatcga
   148801 aaatctggta gcgcgtattt cggcgatctt ccgaggtcgg gacttcattg atcaacactg
   148861 cagtctgatg aaagttccaa ggacctaccg caatcttagg atagatgttg aacatcacac
   148921 ggtttatcgt ggtgaagaga tgattgctct gacccgccgt gagtatgacc ttttggcgac
   148981 acttatggga agcaagaaag tattgactcg tgagcaattg ttggaaagtg tttggaagta
   149041 tgaaagtgcg accgagacaa atatcgtaga tgtctatatc cgctatctac ggagcaagct
   149101 tgatgttaaa ggccaaaaaa gctacattaa aaccgtgcgt ggtgttggtt acaccatgca
   149161 ataatagaaa agcagttgca gttgtgtaac tgcttttttg aggagttttt atatattgac
   149221 atgcagtcgg gtctttgcta caatcgtttt aggagggtat atagatgaaa attttgaaaa
   149281 aaatgatgca agttctacta gcagtctttt tctttggttt gctagctaca aatacggtat
   149341 ttgcgaatac cacaggtggc cgatttattg ataaggataa tagaaaatat tatgtaaaag
   149401 atgatcataa agcaatctat tggcataaaa tagacggtaa aacctactat tttggtgatg
   149461 gaggagagat ggttgtcggt tggcaatact tagaaattcc tggaacaggt tatcgtgata
   149521 atttattcga taaccaacca gttaatgaaa ttggccttca ggagaagtgg tactattttg
   149581 gacaagatgg tgctttgcta gaacaaacag ataaacaagt actagaggca aaaacgtctg
   149641 aaaatacagg aaaagtatac ggtgaacaat atcctctatc tgctgaaaag agaacttatt
   149701 attttgataa taattatgct gtaaagacag gctggattta tgaagagggt cattggtatt
   149761 atttaaataa gctaggaaat tttggcgatg attcttacaa tccactacca attggtgaag
   149821 ttgctaaggg ttggactcaa gattttcatg ttactattaa cattgataga agcaaacctg
   149881 ctccatggta ctacctagat gcttcaggta agatgcttac agattggcaa aaagtaaacg
   149941 gaaaatggta ttattttggc tcctctggtt ctatggcaac aggttggaaa tatgtacgag
   150001 gcaaatggta ttacttagat aataaaaatg gtgatatgaa gactggttgg tatcaagatg
   150061 gttcaacttg gtactattta gatccttcta atggagatat gaaaataggt tggacaaaag
   150121 taaatggaaa atggtattat ctcaattcaa atggagcaat ggttacaggt agtcaaacta
   150181 tcgatggtaa agtttataac ttcgcttcat ctggtgagtg gatttaatgt tggaggatat
   150241 ataaaatgaa gcttttgaaa aaaactatgc aagctggact aacagtaatt ttctttggtt
   150301 tgctagctac gaatacagta tttgcagata actctgaagg atggcagttt gtccaagaaa
   150361 acggtagaac ctattacaaa aagggggatc taaaagaaac ctactggcga gtgattgatg
   150421 gtaagtacta ttattttgat tctctatctg gagagatggt tgtcggctgg caatatatcc
   150481 cgtttccatc taaaggtagt acaattggtc cttacccaaa tggtatcaga ttagaaggtt
   150541 ttccaaagtc agagtggtac tacttcgata aaaatggagt gctacaagag tttgttggtt
   150601 ggaaaacatt agagattaaa actaaagaca gtgttggaag aaagtacggg gaaaaacgtg
   150661 aagattcaga agataaagaa gagaaacgtt attatacgaa ctattacttt aatcaaaatc
   150721 attctttaga gacaggttgg ctttatgatc agtctaactg gtattatcta gctaagacgg
   150781 aaattaatgg agaaaactac cttggtggtg aaagacgtgc ggggtggata aacgatgatt
   150841 cgacttggta ctatttagat ccaacaactg gtattatgca aacaggttgg caatatctag
   150901 gtaataagtg gtactacctc cgttcctcag gagcaatggc cactggctgg tatcaggaag
   150961 gtaccacttg gtattattta gaccagccaa atggcgatat gaaaacaggc tggcaaaacc
   151021 ttgggaacaa atggtactat ctccgttcat caggagctat ggcaactggt tggtatcaag
   151081 atggttcaac ttggtactac ctaaatgcag gtaatggaga catgaagaca ggttggttcc
   151141 aggtcaatgg caactggtac tatgcttata gctcaggtgc tttggcagtg aatacgaccg
   151201 tagatggcta ttctgtcaac tataatggcg aatgggttcg gtaatgacag ggcgcttata
   151261 attatattag aacactcgct taatcaaaga agtgactttg ttgtacttga cctgacgatt
   151321 ggggagatta aaagcatgtg aaatctacac atgctttttc gttagttatg agtgttgaac
   151381 ttgactaacc attgacaaaa gataagagca attaaaataa gatacaaaaa tatcgatgct
   151441 aactgcaccg aaacgcccga tgctatggat agggctaata gggagagcag ggacggggcg
   151501 agaatgtcca ctgtgctcag agcagagccc accgtcccca tcttgtcact ggggatatgg
   151561 gcaaagacag ctgcttgtag gcgagggctg agaatgccga taatcgtaga actgatgaaa
   151621 ctggtcatga aaattacgat ataggcttga caaaggatac tagttattag agtcaatagg
   151681 gaaatctcac agaaaaccaa gaggtgcgtg aaacggatat ttttaaatag attactgctg
   151741 gtcatattgc caaggatagc tccacaagac atgatgatgg agagcagggc gaagagttgc
   151801 ccaatgctca gttgtgctag tgtctgttgg atgaagcgga gggcaatcag ccgaggggac
   151861 acatccaaga tggcaatcat actggtcgtc agaaacagta gtatgacggt atcttttaac
   151921 ctcaggagca cagccagcga ctgtttaaga tgttgaaaat atttcttaaa actcagtgct
   151981 gtatgtgaca tttcaatcct tttttcaacc tcatacaagg tatgtcgaat aacatacagg
   152041 cccaaaaagg caatgacaaa agtcagagtg ttgataaggg aaatagtttg aatacttata
   152101 acattgataa ggaatgcgcc agccagattg gcgacaatgc ggacaaccct catcagagac
   152161 tgcctgaacc ccatggcatc atgcaggtcg tccttaatta cactgatgta gagggcgttc
   152221 atcatgtagg cagacaggta gctcaaggtg tcagagatga ggttgatgat gacaatcata
   152281 atgactgaaa ctaatgaaaa gggcgacaag acgagaaata ctgtcaaaat agcgtagagc
   152341 aggattttga ttttggcaat acagagtgcg tgtttgactc tattttcttg aaaatctcct
   152401 agaatcctga gaaagagttg cgatagtagg ggaaccatct ctgaaatgga aatcagtaaa
   152461 atcgctagcg gagcgaaatt gtactgagcc acataattga taatggcgag gtagaaaata
   152521 ctgtcgccga atgatgaaaa acagctgttt agcagcaact gtctatatat gttgtttgtc
   152581 caaaataatt tcatacattt ctccttatgt ctgcacatcg aatgggaatt tattatttaa
   152641 tagacaccaa tataccccat gcttcctatt ccgaagtcaa acaaatctgc tttaccacta
   152701 tctccttgaa acatcagtaa accgtgatca tctcgttcag aacatgctaa aattacctgt
   152761 tggatttttt tcatcagtaa tttgttttga ttgtagacag tggtttgtag taagctagtt
   152821 attccgtggc aatatcctgt catcattttt agatgatggt taaaaacaaa ttcttgatat
   152881 ttactaataa tatctttgtt tccgtcacaa tcgtacatac aaagatataa gattattccg
   152941 gaaattcctt cgcaccaaga aagttataaa tttcctaaat tttcagtatt agaagtaact
   153001 ttttctaata atttttttaa ttcagtatgg aatgtatgga gatcattata gaacatagaa
   153061 ggttctaaga ctttagaata ggcaaataaa gcatatgcaa ttccacaata ttcatgagca
   153121 aagctatagt ctaaaatgct ttctttggct gtatctcttt gtaggaaata atgataaatt
   153181 tccccatata ctattgtgga tgaaagtttt aagagtattg tcattggtaa aatgatagta
   153241 ttttattaat gataatagga catcagattt tcccaatgca aagtctattt cctctagagt
   153301 atcataattc tctattaatt tcttagcggt gacgtttgct aattgtagat agtattgatt
   153361 tttactgata gaaaataaat gtaggagtaa ctatagatag cctgcatcac caaatagcag
   153421 tgagtattga tattcatatg tgtgtgtcgt tctaattgtc actgccttct tgatgataga
   153481 gagtatttta gaatccagtt ctggggggta caatttattt agatgaaaca gtagtccagc
   153541 tattccgtgt tggaatgata aattacttac gaaatttcca aattctgttg aagaagtgat
   153601 ccttccttca gaatttacag ttttatctag taaaaatcgt agaacactat tacattctgt
   153661 tttgtaatca tatttatgtt cctctatttt tttaattttg actaattatt tgtttgactt
   153721 aaatttagta gacattgtaa ccaaaatagt tgctcatctg tgagctgacc ttgagtatgt
   153781 gatagttcta gtaattgaat aggatccttt aggtagattc aatcaatcta taacacaaca
   153841 acataataat acttttagga taacttgtca aatattatag taaaatgaaa taataacagg
   153901 acaaattgat caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact
   153961 attctagttt caatctacta tagtatatat ttttacatct tgaattgtca aattaagtgt
   154021 ataactttac cgtagcatac ttcataaggc gttttccact taagaaattt tcgtggtcga
   154081 ttatttagaa cctgtattca caaaaaaatg ttaaactaga gatatgatac gcaaagcata
   154141 tgatactgat ttaaacgatc aagagtgggc gaagattgaa ccctatttct ccaaacaccg
   154201 cacctataaa tggccgaaac gagtacttgt taatgagact ttgtacgtca ctaaaacagg
   154261 ttgtcaatgg cgcatgctcc ctcacgactt tcctctttac ttaatggtat ggagtttctt
   154321 tcgtcgttct atgacgacag gttggttcca ggtcaatggc agatggtact acgcttatag
   154381 ctcaggtgcc ttggcagtga atacgactgt agatggctat tctgtcaact ataatggtga
   154441 atgggttcgg taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat
   154501 ataataaaat agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct
   154561 agtaaaagga aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt
   154621 taatagggga acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg
   154681 tggaggtgac ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata
   154741 ccttgtccat ggcggtttat gcctcactgg agtatttgga tatcacagaa gcctgcattc
   154801 gttgtgagat tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca
   154861 gcatagcggc cattcgtgcg gtatttgact actatcaggc tgatctgtct catgatgtac
   154921 tagaaatctt ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg
   154981 ctaagacctg tctcagtgac caacctattc gctttatcaa gaacgtagga tttacagaac
   155041 ttgagatgga tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc
   155101 gtgaagccat ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct
   155161 tgggagaatt aacccagcaa gcagaagttg caatttcaca aaaagatgct gaaggactgg
   155221 gacaaatcct cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg
   155281 cagacttttt ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg
   155341 gtgggctagg aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag
   155401 cagaaagatt agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg
   155461 ttcctacgca aatattgcta ttattaaata ttggggaaag aaaaaagaaa aagagatggt
   155521 gcctgctact agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc
   155581 gcctttacca gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga
   155641 ggtcgagcat gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt
   155701 tgtccgtatc gatactcaaa acaatatgcc tacggcagcg ggcctgtcct caagttctag
   155761 tggtttgtcc gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag
   155821 tcagttggca caggaagcca aatttgcctc aggctcttct tctcggagtt tttatggacc
   155881 actaggagcc tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact
   155941 agctatgatt atgttggtgc tagaggacaa gaaaaaacca atctctagtc gtgacgggat
   156001 gaaactttgt gtggaaacct cgacgacttt tgacgactgg gttcgtcagt ctgagaagga
   156061 ctatcaggat atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac
   156121 ggagaaaaat gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta
   156181 tctgacggat gcctcttatg aggctatggc ctttgttcgc cagcttcgtg agaaaggaga
   156241 ggcctgctac tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga
   156301 cttggagtat ttgtcagaaa ttttcggtca gcgttatcgc ttgattgtgt caaaaacaaa
   156361 ggatttgagt caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat
   156421 atgctatttt agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg
   156481 ctgagattgc tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg
   156541 acttaaggcc taatcctgac tacagcttga ttcaagaaac gattgctttg atgggagact
   156601 tcctcgctgt tcgcggtcag aatttaagac ctttttccct aaaaatctgt ggcaaaatgg
   156661 aacgagaagg gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca
   156721 aggctttact ggctctctat aatctttcgg ttgatcagaa tctcttgttc aagctgacta
   156781 gcgctgtctt gctcaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg
   156841 cagaggattt ggttctctac cagtcatttg atcgccagaa ggcggctgct tggttagaag
   156901 aagaaaactt ggcgacagtt ctggagcgtg attggggatt ttttatctca caagtgaaac
   156961 caactttaga atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca
   157021 tggtccagca aatcaagcaa aatatcaatc aaaatttttt aacttcctca aaagaaacgg
   157081 tggtttcttt ggtcgaagcc ttggagcagg ggaaagccga aaaagttatc gagcaagtag
   157141 aagtagccag caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac
   157201 agttgaaaga agccagtcaa gatttgcaag ctgttgctaa gagtagcggt gctggtggtg
   157261 gtgactgtgg tattgccttg agttttgatg agcaatcaac tgaaacccta aaaaatcgct
   157321 gggccgatct ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt
   157381 aaggacgagc atatccgcta tgctcttgag cagaaaagtt cctataatag ctttgatgag
   157441 gtggagctga ttcattcttc cttgcctctt tacgacctgg atgaaatcga tctgtcgaca
   157501 gaatttgcag gtcgcaagtg ggactttcct ttctatatca atgccatgac gggtggaagc
   157561 gataagggaa aagaaatcaa tcaaaagctg gctcaagtgg cagaaacctg tggaatttta
   157621 tttgtgacgg gttcttatag cgtagccctc aaagattcag cagatgactc tttttctgtt
   157681 aagtctagcc atccaaatct ccttcttgga accaatattg gattggacaa gtctgtcgag
   157741 ttaggtcttc agactgtaga agagatgact cctcttctcc tgcaagtgca tgtcaatgtt
   157801 atgcaggaat tgctcatgcc tgagggagaa aggaagttca gaagctggca atcgcatctg
   157861 gcagactata gcaaacaaat ccctgttccg attgtcctca aggaagtagg ttttggaatg
   157921 gatgtgaaga ccatcgagag agcctatgaa ttgggcgttc gaacctttga cctgtcaggt
   157981 cgtggtggca ccagctttgc ttatatcgaa aatcgtcgca gtggccaacg tgattatctc
   158041 aatcaatggg gccaatctac catgcaagcc cttctcaatg cccaagactg gaaagacaag
   158101 gtcgaactct tggtcagtgg tggcgttcgg aatccgctgg atatgattaa gtgtttggtc
   158161 tttggtgcca aggctgtagg actgtctcga acagttctgg aattgattga aagctacacc
   158221 gtcgaagaag tgattgacat tgttcaaggc tggaaagacg atctgcgttt gcttatgtgt
   158281 gctcttaatt gtgctaccat agcagatctg caaaaagtag actatcttct ttatggaaaa
   158341 ttaaaagaag caaaagatca gatgaaaaag gcgtaaccac cgcctttttt ccatcttcag
   158401 actgaggtga cttttttgaa ttgtgataaa atagaaggga gaggatgaaa ctatgagaaa
   158461 atttaaaatc tttttattta tcgaagtctg tcttttgaca ggagctctga ttttgatggt
   158521 atcagagcat ttttcgcgtt ttctgctgat tctattcctc tttttgcttt tgattcgcta
   158581 ttacactggt aaagagggca ataatcttct gttagtggtg gcaagcattc ttttcttttt
   158641 catcgtcatg ctcaatcctt ttgtgattct agctattttt gttgcggtca tctatagtct
   158701 ctttcttctt tacccgatga tgaaccagga aaaagagcag acaaatttgg tttttgaaga
   158761 ggttgtgacg gttaagaagg agaaaaatcg ttggtttggc aatctccatc atttttcaag
   158821 ctaccagact tgcaagtttg atgatatcaa tctctttcgt ctcatgggta gggacactat
   158881 tcatctggag agggtcatcc taaccaatca tgacaatgtc attatcctca gaaagatggt
   158941 aggaacgact aaaatcattg tacctgttga tgtggaagtc agtctcagcg ttaactgtct
   159001 ctatggtgat ttgacttttt tcaaccagcc caagcgagct ctccgcaatg aacactatca
   159061 tcaggaaacg aaagactatc tcaagagtaa caagagcgtc aagattttct tgaccgctat
   159121 gattggggat gtggaggtgg ttagaggatg aaaaaacaag cttatgtaat cattgctctc
   159181 acctcctttc tgtttgtctt atttttctcc cacagcttgc tggacatcct tgactttgac
   159241 tggtctatct ttctgcacga tgtcgaaaaa acagaaaaat ttgtcttttt attgttggta
   159301 ttcagcatgt ccatgacctg tctcctagct ctgttttggc gaggtgtcga agagctttct
   159361 ctaagaaaaa tgcaggctaa tcttaagcgt ttgttggcag ggcaagaagt ggttcagctt
   159421 gcagatccag atttggatgc cagtttcaag tccttgtcag gtaaacttaa cctcttgaca
   159481 gaagctcttc aaaaggctga aaatcacagc ctttctcggg aagaggaaat catcgagaaa
   159541 gaacggaagc ggattgctcg ggatttgcac gatacagtca gtcaggagtt gtttgcggcc
   159601 catatgattt tgtcaggtgt cagtcagcag tctttgaaat tggatagaga aaagatgcag
   159661 acccagttgc agagtgtcac agctatttta gaaaccgccc agaaggattt gagagtcttg
   159721 ctcctgcatt tgcgaccggt tgaattggaa cagaagagtc tggttgaagg gattcaagtc
   159781 ctcttaaaag agcttgagga caagagtgat ctcaaggtta gttttaagca aaatgtgacg
   159841 aaattaccta aaaaaatcga ggagcatatc ttccgtattc tgcaagaatt gatcagcaat
   159901 actctccgcc atgctcaggc ctcttgtttg gatgtctatc tctatcagac ggatcttgaa
   159961 ttgcaactga aggtggtgga taatgggatt ggtttccagt cggggagctt cgatgatttg
   160021 agttatggac tccgcaatat caaggagcgg gttgaagata tggcaggaac ggttcagtta
   160081 ttaacagctc ccaagcaagg gctggcagtt gatatccgta ttcccttgct cgataaggaa
   160141 tgataaagga gtaaagatga aaattttact agtagatgac catgaaatgg tccgattggg
   160201 cttgaaaagc tactttgacc tccaagacga tgtagaagtt gtgggtgaag catccaacgg
   160261 atctcagggc attgacttgg ccttggaatt acgtccagat gtcattgtca tggatatcgt
   160321 catgcctgag atgaatggga ttgatgcgac cttgactatc ctcaaagaat ggcctgaagc
   160381 caagattttg attgtgagct cttacttgga caatgaaaaa ataatgccgg ttttgaatgc
   160441 tggtgccaaa ggctatatgc tcaagacttc tagtgcagat gaattgcttc acgctgtccg
   160501 taaggtggct gctggcgagt tggccattga gcaagaggtc agcaagaagg tcgaatacca
   160561 ccgcaatcat atggagcttc atgaggacct gactgcgcgt gagcgagatg tactacaact
   160621 catcgccaag ggctacgaaa atcagcgtat cgcagacgaa ctttttatct ctctcaagac
   160681 ggttaagacc cacgtgtcca acattcttgc caaacttgaa gtcagcgatc gtacccaggc
   160741 ggctgtctat gcctttcagc accacttggt ggggcgggaa gatttttaat tgttatataa
   160801 gaataatatt gaggaaatga ttgagttgag taccaaagaa gtgagcaagt acctctagca
   160861 tggttgaaaa gcgcagtcat tacttgaaaa aagtcgctcg tttatgtcat aatagaggat
   160921 atttaaagaa ggcggtagat ttcttgattc tatagtagat tgagaaattt agaatggtat
   160981 gctataatta cattaggagg atagaataat gaagaaaact ttttataaaa aattgggtat
   161041 ttcaattatt gcgagtactt tattggctag ccagttatcg acagtatctg ctttgactgt
   161101 tatttctagt acaggtgaag aatatgaggt aagtgagaca ttacagaaaa gtccaggaac
   161161 taataatttg tcacttcctg agatttcgcc aacttatggt caatattata caaatcagtc
   161221 agaagtcatt attggcaaaa atgatttagt taaagtaaaa aatactttac aatatcctta
   161281 ctctacatca gcttatgtaa aagcaacatt caaaattaaa aatgccgatt cagtagaaat
   161341 aggtacaggt agaggaagtg cttcctttat caaagacaat gttttgatta cagcagctca
   161401 tgtcgtttat gaccgtgaat ccaaaacaga agcgactgaa gtagagatta tgcctgcggc
   161461 tactccagat agtaatccat ttggtgaaat aaaagtcaaa gaagttcgtt atttaaaaga
   161521 atttcgaaat actgctccaa atgagcttac tacctatgac ttagcagttt taattttgga
   161581 agaaccgatt ggtgctcaat tggggacgtt aggacttccc aataatttag aaaatactaa
   161641 aaatctagat gtaacagtta cgggatattc tgctgttaat aagggtatta agcagatgta
   161701 tactgataca aaaacgatac ttcaagatac aaatgatttt ttattctacc aaatagatac
   161761 aaagggtggt gctagcggtt cagcagtgta tgattctaat aataggattg ttggagttca
   161821 tactaatggg agtgaccctg aacaaatgaa ttatgctgtt aagttaaatg agaaagctct
   161881 atctttcatc tactctgtta ttaaagggca ttctattgat ggatggaagt tgattagtga
   161941 tacttggtat tattataaga atagtaataa acaaacgggt tggcaaaaga taaatgatac
   162001 atggtactat ctagatgctt caggtaagat gcttacagat tggcaaaaag taaacggaaa
   162061 atggtattat tttggctcct ctggttctat ggcaacaagt tggaaatatg taggaggaag
   162121 atggtattat ttcgataaga ccaatggtga tatgaagact ggttggtata aagatggctc
   162181 aacatggtac tatctagatc ctactaatgg agacatgaaa aaaggttgga taaaagtagg
   162241 aggaaactgg tattatctca attcctctgg agcaatggtt acaggtagcc aaactatcga
   162301 tggtaaagtg tataatttcg cctcatctgg tgagtggatt taatattgga ggatatatag
   162361 atgaaaattt tgaaaaaaac tatgcaagtt ggactgacag tatttttctt tggtttgcta
   162421 gcgacaagta cagtatttgc gaataccaca ggtggccgat ttgttgataa ggataataga
   162481 aaatattatg taaaagatga tcataaagca atctattggc ataaaataga cggtaaaact
   162541 tactattttg gtgataaagg agaaatggta gttggttggc aatacataga aatccctggg
   162601 acaggctatc gtgataattt attagacaac caaccagtta atgaaattgc ccttcaggag
   162661 aagtggtact attttggaca agatggtgct ttgctagaac aaacagataa acaagtacta
   162721 gaggcaaaaa cgtctgaaaa cacaggaaaa gtatacggtg aacaatatac tccatctgct
   162781 gaaaagagaa cttattattt tgataataat tatgctgtaa agacaggttg gatttatgaa
   162841 gagggtcatt ggtattattt aaataagcta ggaaattttg gcgatgattc gtacaatcca
   162901 ctaccaattg gtgaagttgc taagggttgg actcaagatt ttcatgttac tattgacatt
   162961 gatagaagca aacctgctcc atggtattac ctagacccag aaactggcat tatgcaaaca
   163021 ggatggcaat atctaggtaa taactggtac tatctccgtt catcaggtgc tatggcaact
   163081 ggttgggtga aagatggttc aacttggtat tatctagatg ctcaaaatgg tgatatgaag
   163141 acaggttggg cttatgttgg taacagttgg tactaccttc gttcatcagg tgcaatgtct
   163201 accggttggg tgaaagatgg ttcaacttgg tactacctaa atgcaagtaa tggagatatg
   163261 aagacaggct ggttccaggt caatggaaaa tggtactatg cttatagctc aggtgcttta
   163321 gctgttaata ccacagtagg tggctactac gtcaactaca atggtgaatg gattaagtaa
   163381 tgaaggctaa ttgtaaactg tgatggatac ttaacttttt ataataggtg gataaaagtc
   163441 tttaaaatag aaaaaaacgc atattattag gtgttcaaaa accttgataa tatgcgtttt
   163501 tgtagtggaa agatttcttc tttagttgat ttcctatcac tattatataa tgctttttga
   163561 tttcaatcta gtataaagaa aaccaaggag aaaccatact tccagcatga ttgaaaagcg
   163621 cagtcattac ttgaaaaaag tcgctcgttt atgttataat agactgtatt taaaaaattt
   163681 taaggagaaa tgacagaatg tctgtatcat ttgaaaacaa agaaacaaac cgtggtgtct
   163741 tgactttcac tatctctcaa gaccaaatca aaccagaatt ggatcgtgtc ttcaactcag
   163801 tgaagaaatc tcttaatgtt ccaggtttcc gtaaaggtca ccttccacgt cctatcttcg
   163861 acaaaaaatt tggtgaagag tcactttatc aagacgttat gaacgctctt ttgccaaacg
   163921 cttatgaagc agctgttaaa gaagctggtc ttgaagtggt tgctcaacca aaaattgacg
   163981 taacttcaat ggaaaaaggt caagactggg ttatcactgc tgaagtcgtt acaaaacctg
   164041 aagtaaaatt gggtgactac aaaaaccttg aagtatcagt agatgtagaa aaagaagtaa
   164101 ctgacgctga cgttgaagag cgtattgaac gcgaacgcaa caacttggct gaattggtta
   164161 tcaaagaagc tgctgctgaa aacggcgaca ctgttgtcat cgacttcgtt ggttctatcg
   164221 acgatgttga atttgatggc ggaaaaggtg aaaacttctc acttggactt ggttcaggtc
   164281 aattcatccc tggtttcgaa gaccaattgg taggtcactc agctggcgac actgttgatg
   164341 ttatcgtaac attcccagaa gactaccaag cagaagacct tgcaggtaaa gaagctaaat
   164401 tcgtaacaac tatccacgaa gtaaaagcta aagaagttcc agctcttgac gatgagcttg
   164461 caaaagacat cgatgaagaa gttgaaacac ttgctgaatt gaaagaaaaa taccgcaagg
   164521 aattggctgc tgctaaagaa gaagcttaca aagatgcagt tgaaggtgca gcaatcgata
   164581 aagctgtaga aaacgctgaa atcgtagaac ttccagaaga aatgattcac gaagaagttc
   164641 accgttcagt aaacgaattc cttggaaact tgcaacgtca aggtatcaac cctgacatgt
   164701 acttccaaat cactggaact actcaagaag accttcacaa tcaataccaa gcagaagctg
   164761 agtcacgtac taagactaac cttgttatcg aagcagttgc caaagctgaa ggatttgacg
   164821 cttcagaaga agaaatccaa aaagaagttg agcaattggc agcagactac aacatggaag
   164881 ttgcacaagt acaaagcttg ctttcagctg atatgttgaa acacgatatc acaatcaaaa
   164941 aagctgttga attgattaca agcacagcaa cagtaaaata atcttaataa acaaaaagcc
   165001 cacctgaatt ggtgggtttt cttatgcact attttccaaa aatctctttg aggtctgcgt
   165061 ctgtaatccc aatcatggcg gggatgctgt cccagttttc ttcggttagg gtgtaggatt
   165121 gttcagaggt acttgatgtg gcagtttcag agacagcttg ttgcttttct tcaacatttt
   165181 caattagatc actgaagcgt tcaatcagat aggtttttct ggcagttccg atatgttggg
   165241 tagcatagtc gaaggcctgt aattcgccta gtaagataag cttgcttttg gcgcgagtaa
   165301 tggctgtgta gatgagattg cgctccagca tacgcctact agcactggtg atcggtagga
   165361 tgacaacagg gaactcactt ccctgtgatt tatggatgct catggcatag gccaggcgaa
   165421 tcttgtacca ttcgttacgt gggtaagaga cctcgttgcc atcaaaatca atgacaatct
   165481 cgtcttgttt cgactcggtg tatttaccag gaatcaggtc tgtgatgact cctaaatctc
   165541 cattaaagac attgatttca gcatcgttga ccaggtgaat gaccttgtcg cccttacgaa
   165601 agtggcattg gggagcttca aaactaagtt ggtctttttg tggtggatta aggaggtctt
   165661 gcatgagctg gttgatggca tcaatccctg cagtccctcg gtacatggga gccagaacct
   165721 gaatatcacg agcagggata ccacttctga gggcggcacc taagattttt tcaatggtag
   165781 caggaatatg gccactagca atttcaaagt aggaacggtc agcttttttc tgggtgaaat
   165841 cggctggcaa gatgccctgt cgaatttgac tagctagggt aacgatggtt gattcttcgc
   165901 tttgtcgata aattttttcc aagcgagtct gaggaatcaa aggaatatga agcagatccg
   165961 ctagaacctg tccaggactg acagaaggca actggtcgct atctcccacg atgagaattt
   166021 tactgttaga agagatgttg gagaagagtt gattggccag ccaagtatcc accatggaaa
   166081 attcatccac gatgataaag tcagcatcca gataatcttc cagatgactg gtgtcatcgt
   166141 cacctgtcat tcctaaatga cggtgtatgg tcgcacttgg caagcctgtc aattcattca
   166201 tacgtcgagc agctcgacca gttggagcag caagaagaat cggcagattg ctttttttcc
   166261 tgaggtcaag tccttctaaa agggcataaa cagcgatgat cccattgata acagttgtct
   166321 taccagtacc aggtccacct gtcaggataa agaccttgtt ctggatagca tcacagatag
   166381 cttgtttttg aatgctatca tactcaatcc ccagttcttc ctcgatagta gcgatatgtt
   166441 tttgaatggt ttctaaatcc tggctcttct gttttccttt ttcaaggata cgaaccaagt
   166501 gactgcggat gccttcctca gcgaaaaaga gactattatc aaagattttg gtatcaattt
   166561 gctgaacctt gtcttcttca atcaggtagg agagttcttg ggcaacttga ctgggatcca
   166621 gttctacggg gcgggaagac tcaaggagag taagggtttg ttctagcaaa tcccgtgctt
   166681 caacataggt gtcccctgtt tccatacagg cctgaaaaag actatgaatt agaccggcac
   166741 ggaagcgttc aggagcctga ctttcgatgc ctagttcttc cgctagttgg tcagcaatag
   166801 taaagcccaa acccttgata tcctcgacca actggtaggg ataattttca accacatcaa
   166861 gggtttcttc cttgtaaaag tcttgaattt gaaaggctag tttgttggga atgccgtagt
   166921 tggctagttt ggccaaaacc atctccgttc cgtagttgag acggagagtg gagacgaaag
   166981 cctcgcgatt ttttgcagag agtcctgcga tgtcttctaa cttttctggg tgttgcaaaa
   167041 tttcgtcaat ggtattgtcg ccataggtgt ccactatttt ctgagctgtc ttgagaccaa
   167101 ttcccttgaa atggctactt gaaaagtact tgaccaagcc cttgctagtt ggttttgcac
   167161 gttcataacg gttgatttgc agttgttccc catacttgga gtgctggaca atttgccccc
   167221 aaaaggtata gtcttctccc tcaatcacgt cagccatggt gccggtaaca atgatttcaa
   167281 aatcatcaaa atcctctgcg tctgtatcgt cgatttctag gagaaggata cgataaaaat
   167341 tgctgggatt ttcaaaaata atccgttcaa tggttcctga aaaataaact tccataagat
   167401 tcctttgcat aaataggtga gagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc
   167461 ttcgccttgc cgtatatatg ttactgactt cgtcagttct atctacaacc tcaaagcagt
   167521 gctttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataact
   167581 ttgtttctat cttaatcaaa ctgggtagtg aataatcata ttatcacgat agaagaagag
   167641 gctgagattg ctgattctcg gcctcttcga tttcttaaaa tgttccgata cgggtgattg
   167701 gccagaagcg gaatttagct tcccctgtga tatcttttgc tttgaaggta cctacgtggc
   167761 ggctgtcgct cgaaaccaag cggtcgtctc cgaggagaag gtattctcct tctggaacag
   167821 taaagctaaa gttggtgtta tagttgacat cgactgtgaa ggattgggct ttttgagcga
   167881 tacttctaaa gaaagttcct ttatttcctt caaagccctt gcctgagtaa gtgctttgga
   167941 gtttgtcgtc cttgaagcgt ttgatgtagt ctgctaggta aggctcgtcc gtctctttgt
   168001 cattgatgta aagtttatcg ttttcgtaac ggatggtgtc gccaggcatt ccgataacac
   168061 gtttgacgat gtccttatta ccgtcttcct catgggcaac cacgatatca aatcggtcaa
   168121 tagggagatg tttgacaaca aagaggattt caccatccgc cagggtagga tccatggaat
   168181 gcccttctac gcggacatta ctccaaaaaa agatacggct caaagctagt aatgacagaa
   168241 tcaggaggaa caatccccac tcttttaaga aatttttaaa tgaattcata acttaccttt
   168301 ctaagcgttt tttcgctttt tcagtatttt taaagtgtag cttggcgcag aagctgagtc
   168361 cctgcatacc ataggcttgc aaaatctggc tagctacctt atcagaagcc gttccagctc
   168421 cacttggaag ttgatagccc agttctcgtc ccagattttc aagattttcc agaaagagat
   168481 cacgcgcaat gatagaagaa actgcgacag ccaagtattt gccctcagcc ttttcttcta
   168541 agctgatagg attactgaaa cgattggcct cttgtgccaa gtacttgtca taatttttag
   168601 cactggtaaa ggcatcaatc acaatttttt caggctgaac acctttttga aggaggagat
   168661 agatagcctg attatggagg gctaccttaa cagaaacagc attgtagcgg tctccgatga
   168721 tctcgttgta cttgcttggt gagagaagca gtgcctggtg ctggattttt tcctttagga
   168781 taggggcaat ctgacgaatc ttttggtcgg tcagagtctt agaatctccc acaccgagtt
   168841 ttcgcaagaa gtcatgctgg tcaggtgtga caaaggaagc cacaactgca agtccaccaa
   168901 agtaggaacc atttccaacc tcatcagtcc caatcaaagg aagattttga tcgctgtttt
   168961 cttctacaat ttgatagcca aagaaacgag cgtatttctc ggccccctca ccctgaagca
   169021 agacctttcc agaagtatag atagaaaccg ttgcttgagg tagtcgcaaa aagtagcgaa
   169081 tatagggatt cttgctggga gccagactgg tttgatagtg ttcaagaaaa gactgaatct
   169141 ccttttcgct tggtgtgagt gttatacttg ccatagtttc tattgtacca caaaagcagt
   169201 aaaatttgta aaaactgaca aaattagcga attttggtat aatatcgtga ggtgaatttt
   169261 atggcaaatc taaatcgatt caaatttaca ttcgggaaaa aaacgttaac cttgacaagc
   169321 gagcatgata atctctttat ggaggaaatc gccaaggttg cgacagaaaa ataccaagca
   169381 attaaagaac aaatgcctag tgcagatgat gaaacaatcg ctcttttgtt ggcagtcaac
   169441 tgtttatcaa ctcagctcag tcgtgagatt gaatttgacg ataaggagca agaattagaa
   169501 gaactgcgcc acaagcttgt gacttgcaag caagaacaga gcaagattga ggattcctta
   169561 tgatttcact ccttcttcta ttggtcttgg cttggggatt ttatatcggc tatcggagag
   169621 gcctgctctt acaggtttat tacctgattt cagccatggc atcggctttt atggctggcc
   169681 agttttataa ggggcttgga gagcaattcc atttattgct cccttatgca aatccgcagg
   169741 aaggtcaggg aactttcttt ttcccatcgg atcaactctt tcagttggat aaggtctttt
   169801 atgcaggtat tggctacttg cttgtatttg ggattgtcta tagcatcggt cggttgcttg
   169861 gtctcttgtt acacttactt cctagtaaaa aactgggtgg taagttgttc caagtttcag
   169921 cagggatctt gtccatgttg gtgaccttat ttgtcttgca aatggccttg accatcttgg
   169981 cgaccatccc catggcagct atacaaaatc ctcttgaaaa gagtatcgtc gcaaaacaca
   170041 tcatccagag cataccggta acaactagtt ggctcaaaca aatctgggtg acaaatttaa
   170101 tcggataaaa agggcaggag ttttcctagc cctttgttta cagatttgac tcgaatctat
   170161 cagaatgtaa aaagctaata ctcttcgaaa atctcttcaa accacatcag cttccatctg
   170221 caacctcaaa acactgtttt gagcaacctg cggctagctt cctagtttgc tctttgattt
   170281 tcattgagta caatacacct agacattcaa agacaaggaa ataaagatga ataagaaaat
   170341 attagaaaca ttagagttca ataaggtcaa ggccttgttt gagccccatt tgttgaccga
   170401 gcagggcttg gagcaattga gacagctagc tccaactgcc aaagcggata aaatcaaaca
   170461 ggcttttgct gagatgaagg aaatgcaggc tcttttcgtc gagcaaccgc atttcactat
   170521 tctctcaact aaggaaattg caggagtctg caagcgtttg gagatggggg cggacctcaa
   170581 tatcgaggag ttcctactct tgaagcgcgt gcttcttgct agccgagaac tgcaaagttt
   170641 ttatgccaat ctggaaaatg tcagcttgga agaattagcc ctatggtttg agaaattaca
   170701 tgattttccg caattacaag gaaatctcca agcctttaat gatgcaggtt tcattgaaaa
   170761 ttttgccagt gaagaattgg cgcgaatccg tcgaaaaata catgatagcg agagtcaggt
   170821 acgcggtgtt ttacaagact tgctcaagca aaaagcgcaa atgttgacgg aaggaattgt
   170881 tgctagcaga aatggccgtc aggttttacc agtcaaaaac acctaccgca ataagattgc
   170941 aggtgtcgtt catgatattt ctgctagtgg aaacaccgtc tatatcgaac cccgtgaggt
   171001 agtcaaactg agcgaagaaa ttgctagtct gcgagcagat gagcgctatg aaatgcttcg
   171061 cattctccaa gaaatttctg agcgtgtccg ccctcatgcg gctgagattg ctaatgacgc
   171121 ttggattatc ggtcatctgg acttgattcg tgccaaggtt cgatttatcc aagaaagaca
   171181 agcagtcgtg cctcagctgt cagaaaatca agagattcaa ctgctccatg tctgccatcc
   171241 tttggtcaaa aatgccgtcg caaatgatgt ccattttggt caagatttaa cagctattgt
   171301 cattacaggt cccaatacag gtgggaagac catcatgctc aaaactctgg gcttgacaca
   171361 ggtcatggcc cagtcaggat tgccgatttt agcagacaag ggaagtcgtg ttggtgtttt
   171421 tgaagaaatc tttgctgata ttggagatga gcagtctatt gagcagagct tgtctacctt
   171481 ctctagccat atgaccaata tcgtggatat tcttggcaag gtcaaccaac attcactctt
   171541 acttttggat gagttggggg ctggtactga tccccaagag ggagcagccc ttgccatggc
   171601 tattctggag gaccttcgcc tgcgtcaaat caagaccatg gcgacgaccc actatccaga
   171661 actcaaggcc tacggtattg agacagcctt tgtgcaaaat gccagtatgg agtttgatac
   171721 tgcaactctt cgcccgacct atcgctttat gcagggtgtt cctggccgaa gtaatgcctt
   171781 tgaaattgcc aaacgtctag gcctatctga agttatcgta ggagatgcca gtcagcagat
   171841 cgatcaggac aatgacgtca atcgtatcat tgagcaacta gaagagcaga cgctggaaag
   171901 ccgcaaacgc ttggacaata tccgtgaggt ggagcaagaa aatctcaaga tgaaccgtgc
   171961 gctaaaaaaa ctctacaacg agcttaatcg tgaaaaggaa accgagctta acaaggcgcg
   172021 tgaacaggct gctgagattg tggatatggc cctaagtgaa agtgaccaga ttctcaaaaa
   172081 tctccacagt aaatcccaac tcaagcccca cgaaatcatt gaagccaagg ccaagttgaa
   172141 aaaattggct tctgaaaaag tggacttgtc taaaaataag gtccttcaaa aggccaaaaa
   172201 aaaacgagct ccaaaggtgg gagatgatat cgtggttctc agttatggtc agcgtggtac
   172261 cttgactagt cagctcaagg acgaccgctg ggaagcccaa gttggcttga ttaagatgac
   172321 cttggaagag aaagagtttg accttgttca agcccagcaa gaaaaaccag tcaagaagaa
   172381 acacgtcaat gttgtgaaac gaacttctgg gcgaggacct caagctagac tggatcttcg
   172441 aggcaagcgc tatgaagaag ccatgaatga gctagatgcc ttcatcgacc aagccttgct
   172501 taacaatatg gctcaagttg atatcatcca tggtatcgga acaggagtca tccgtgaagg
   172561 agttaccaaa tacttgcaaa gaaataaaca tgtcaagagt ttcggctatg ccccacaaaa
   172621 tgctggaggc agtggtgcga ctattgtcac ttttaaagga tagcagtatt ctggacttta
   172681 taaagtaaaa actgttgaac taatttttac taataaacac attgacaaaa gccaacattt
   172741 tttgtaaaat tagaatcaat taaataccaa caccgaatga agtttaatag aagtggggaa
   172801 tcgtttgatt ttccatgact gtaaatggac ggaactctgg agagaccgta aaggcaccga
   172861 aggggcaagg caggcaactg ctcaaactct caggtaaaag gacagagcta ggatagacgg
   172921 ctttttagca tttatctaag cattccagag tacatgtatc ttgcatgtgc tctttctttt
   172981 ggggttgaaa cgataggaga aggaaatgtt agaattgctt aaatcaatcg atgcttttgt
   173041 ttggggaccg cccctcttga ttttattgct cggaacaggg atttacctaa ctattcggct
   173101 aggactcttg caggttttgc gtctgcccaa ggcctttcag cttattttta tccaggataa
   173161 gggacatggt gatgtatcca gttttgcagc tctgtgtaca gccttggcat caactgttgg
   173221 aacaggaaat atcataggag ttgcgacggc tatcaaggtt ggtggaccag gagctctatt
   173281 ttggatgtgg atggcggctt tctttggaat ggctaccaag tatgcggaag gactcttggc
   173341 catcaaatac cgcaccaagg acgaccaagg tgcagtagcg ggaggtccca tgcactatat
   173401 ccttctaggg atgggagaaa agtggcgacc acttgctgtt ttgtttgcag tagcaggagt
   173461 attggttgct ctcttgggaa tcggaacctt cacccaagtc aactcgatta cagaatctat
   173521 ccaaaataca acgacgattt cgccagccat cacagctctc gtcttgtctg tctttgtagc
   173581 gattgcagtc tttggtggac tcaagtctat ttctaaggtt tcaactactg ttgttccttt
   173641 tatggccatc atttatatct taggaactct tacagttatt ttctttaata tcggaaaaat
   173701 ccctgccaca atcgctttag tctttacctc agcttttagt ccccttgctg tggtaggtgg
   173761 atttgctggt gctagcgttc ggatggctat tcaaaatggt gtggcgcgtg gtgtgttctc
   173821 aaacgaatct ggtctaggtt ctgctcctat tgcagctgca gctgccaaga caaatgaacc
   173881 agtagagcaa ggtttgattt ccatgacagg aacctttatt gataccctca tcatttgtac
   173941 tctaactggt ttgaccatct tggtaactgg agtttggagt ggtgacttga atggggttgc
   174001 cttgactcag tcagctttct caacagtctt ttcacacttt gggccggccc tcttgaccat
   174061 cttccttgta ctttttgcct ttacaacgat tctaggttgg aactattacg gagaacgctg
   174121 ttttgagttc ctctttgggg ttcgctttat ctggctctac cgtgtggttt ttgtgctcat
   174181 ggtcttgtta ggaggattta tcgagttgga tatggtctgg attatcgcag atatcgttaa
   174241 cgccttgatg gctctgccaa acttgattgc cctcttggtc ttgtcgccag tcgttattgc
   174301 tgaaactaaa aagtattttg acaaataatg gaatcacaca gctcgtgtga tttttttgcc
   174361 tataaataat ttttatcagc ctgatatata atatatatta tacaagtgat tggaagtgtg
   174421 ataaactaat ataacaacga aaatcttatg agagaataaa gctttatctt agataaactt
   174481 aggaatcagg attttataag attttccaat aatattagtg tcaataataa gaaaagaggt
   174541 atcttatgac aacatttact atccatacag tagagtcagc accagcagaa gtgaaagaaa
   174601 ttcttgaaac agtagaaaaa gccaacaatg gctatattcc caacctaatc ggtctcttgg
   174661 ccaatgcccc gactgtttta gaagcctacc aaattgtctc atctatccac cgtcgcaaca
   174721 gtctgacacc cgttgagcgt gaagtggtgc aaatcacggc agccgtgacc aatggttgtg
   174781 ccttctgtgt cgcaggtcac acagcctttt ccatcaaaca aatccagatg aatgatgact
   174841 tgattcaagc tcttcgcaat cgtactccaa ttgaaacaga tcctaaattg gatacactag
   174901 ctaagtttac cttggcagtt atcaatacca agggtcgtgt aggagatgaa gccttgtctg
   174961 agtttttaga agctggctac actcaacaaa atgccttgga tgtggttttt ggtgtcagcc
   175021 taacaatcct ctgtaactat gccaacaact tagctaatac accaattaat ccagaattgc
   175081 aaccttatgc ctaattcata tctgagtaaa atgaagtctg aaataagcgg actgcgtttt
   175141 tttaaatcct catttaagcg cttttatgtt atactgaaac taacatgatt attggaggtt
   175201 aggatgaaaa aactcccctt agtattttca ggttgtttgc taggtttggc aggagctgga
   175261 aatcttattt tagatacgtt gccggttcta tcccatcttt ttagtctgac tggtttggtt
   175321 ttatggattt actttctaat tctgcatctc tttaattgga aagaaaccaa gcaagaattg
   175381 accaagcccc ctcttttgtc aggaatggca acctttccta tggctgggat gattttatcg
   175441 acctatgtct ttcgcgtatt ctcttatctt cctttggtag cacaagggat ttggtggttt
   175501 tcatttctct tggatttgac cttgattgct gactttacca tcaagtttgc ttgtccaggg
   175561 cggagggttc atgccactcc aagctggacg gttctctatg tggggatagc agtggctgcc
   175621 ttgacctatc ctctggtagg tattatcgaa attgcctatg cgaccttgag ttttggtttt
   175681 ctcttgacct tctatctcta tccccttatt tatagcgatt taaagaaaca tccactccca
   175741 ctagccttgc ttggacaaga aggaatctac tgtgctcctt tctctctact cttggcttct
   175801 ctagttcgag taggaggaac cagcctgccg acttgggtct tgattgtcat gattttggct
   175861 tctcaatcct tctttttctt tgttttaact cgtctgccca acattttaaa acaaggtttt
   175921 caaccagcct tctcagccct caccttccca accattatca cagcgacctc gctcaagatg
   175981 gctcagggaa ttttgaaact tccatttctg gattacctgg tattgactga aaccattata
   176041 tgcctaacta ttttattctt tgtactaggt gcttatctga tttggttacg aaaaaaggtc
   176101 tagctagaaa tagctaaacc ttatttttta tggtttgatg acttcagctc cacccatgta
   176161 tggacgaagt gcttctggga tggtcacaga accatcttca ttttggtaat tttcaagaat
   176221 tgcagccact gtacgtccaa ctgcaagtcc agaaccgttc aaggtatgaa ggagtttcac
   176281 cttgccatct gcttcatcac ggtaacgggt ttgggcacga cgggcttgga aatcttctgt
   176341 gtttgaacag cttgagattt cacggtaatt gttttgtgct ggaatccaca cttccaagtc
   176401 gtaagtcttc gcagctgaga agcccatatc tccagtagag agagcaacga cacggtatgg
   176461 aaggttgagt ttttgaagaa tgttttcagc gttggctgtc attttttcca attcttcgta
   176521 agattcttct ggtttggcaa atttgaccat ttcaaccttg tggaattggt gcaaacggat
   176581 caagccacgc gtatcacgac cggcagaacc agcctcagaa cggaatgacg gactcatagc
   176641 agtgaagtag attggaagat ctttgccgtc taagatttca tcacggtagt agtttgtcag
   176701 aggaacttca gcagttggaa tcaagacaaa gttggtatcg ctgagttcaa aagtatcttc
   176761 cttaaatttt ggatactgac cagtaccaaa catagaatca tggttgacta tgtaaggtgt
   176821 gatgacttca gtatagcctt cttttccatg ttcatccaac ataaagttgt agatagcacg
   176881 ttccaaacga gcaccgaggc ctttatagaa gaggaagcga gcgcctgtta ccttaccacc
   176941 gcgttcccag tcaaggatac caaggtcttc accgagatcc cagtgagctt taggttcgaa
   177001 gtcaaactcg cgtggagtac cccaacggcg aacttccaca ttgtcgtctt cgtcagcccc
   177061 aacaggaacg ctgtcagctg ggatatttgg aagagtcgtt gtaaattctg tcaatttagc
   177121 atcgatttct gccaattcag catccaaggc tttaacctca gcagatagat tttgcatggc
   177181 agcaatcttg tcatctgtat tttccttgtt gcgcttagct tgggcaatct cagcagaaac
   177241 tgtgttacgt tctgctttga gagtttcaac cttgaccaag atgttacgac gtttagcatc
   177301 gatttctttc atttcattca agacagcagc atctacacca cgtgtagcta atttttctgc
   177361 gacagtttca aaatctgtac gaatacgttt gatatctaac ataagaactc ctttatgaaa
   177421 aaagcacgcc tgacaaaacg ttggagtggc agggccacgg ttccatccaa cttcacaggt
   177481 gtgcacttga ttgtgtatgt aattgttact aacggtagaa tttcacctat ccctcctatc
   177541 tgctcgcagt acccgcagac tttctgaaag aagaagataa cctacttatc cgttgctatg
   177601 attatactaa agtttctact tttttgcaaa tagattttta aatttttggc taattgtctg
   177661 aatcagggtc ggaagtttga cgaccttgtc attgcctagt ttttcgcgtg caattttgag
   177721 aatggcacct gagtcttttg aagcaaagag gaattttcct ttgtctgtaa agacttcgaa
   177781 gtggcggctg attttgcgtc cagtgacatt ggctccaatc tgattgatat ggctccaagg
   177841 aatctggata aattgttcga cattgacatc tgggtaaaat tccaaagcct gatctccgac
   177901 aaggaatttc ccaactttcc cagcgataga gaggtaggaa gtgcctgtcg tactgaggag
   177961 tactgttttg ttaagtgatt gggccatgct tagtcttcct tactttctcc aaaaaaggca
   178021 ttgtagaggg ctttaattgc tgctttctct tggtctttat tgacaacaaa cataatagaa
   178081 acttcactag aaccttgaga catcatctgg atgttgattt tgttttcaga tagagcgcgt
   178141 gtcgcagtag cagtcactcc gatacggctc ttcatttttt caccaacaat cataatgata
   178201 gaaaggtcgt gttcgatttc tgcatgatct actttagcct tttgaaccaa ctgacgcagg
   178261 atttcttctt ccttgatggg agttagttgg cgagaacgga gaatgataga aagatcgtcg
   178321 atacctgttg gcatatgttc ccaaccgatg ttaagttctt ccaggatttg cagaaccttg
   178381 cggccaaatc caatctcacg gttcatgagg tatttcgaca tattaatgct gacaaagcct
   178441 gagtcaccag caattcccac aactggaaat tcatcattac tgtgttttag aacgatacga
   178501 gtacctggat ggtcagggtt gttggtattc ttgataacca gaggaatttt tccacggtag
   178561 gcaggaagaa gagcctcgtc atgaaggact gagaagcctg cataggccaa ctcgcgcatt
   178621 tcacggtagg tcaactcagg aatcgagtgt ggttggtgga taataccagg gtgggctgca
   178681 aagataccat caacgtccgt aaagttttca tagaggtcag ctttgacacc agcagcaatg
   178741 atagaacctg taatatcaga tcctccacgt gagaaagtac agatttgatt ttccttagtg
   178801 acaccaaaga aaccaggaat gacaaggact tcattggtgt ttgtcaattc ttcaatcttg
   178861 tcataacttg atggaatgat gcgagcgtga ccaggttcac ttgtgaccat aatcccagct
   178921 tctctagggt gcatatagcg tgcatcaata ccattttggt taaagtaggc agcaatcaat
   178981 ttggcattgt tattttcacc ggctgctagg aaagtatcgt agagaaattc attttcttca
   179041 ataggaagag tggccaaggc gtgaatgctt ttagaaattt tttctagcac agctggtttt
   179101 agtcccaatt cactaaccat agcagcatag cggtcgataa tccagctttg gctcttgcta
   179161 atatcgttac ccgcaacata gtcgcggtag tatttaatca gggcatccgt aaccttagta
   179221 tcttcagcat tgcgtttacc aggcgcagaa acgactacaa aacgacgctc tgaatcgctt
   179281 ttaacgatat ttaaaacttt ttctaattga ctagcagagg caagagaact acctccaaat
   179341 ttaacaactt tcataagaac tcctaaagta agtattctat acgattatag cagaaagaaa
   179401 ggcttttttc aatgaagaaa atgcaatctt gtttgggtga aaaatgacaa gtattttgat
   179461 aataacttgc caacatctat cacttatcgg aatgttaaaa aagttagcgt tttgctgttc
   179521 aaatttgtaa aaata
//
LOCUS       DAVFJR010000002       113771 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVFJR010000002 DAVFJR010000000
VERSION     DAVFJR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 113771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 113771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..113771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.002"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            91..789
                     /locus_tag="VU722_000180"
     CDS             91..789
                     /locus_tag="VU722_000180"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU1771246.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            780..4319
                     /gene="smc"
                     /locus_tag="VU722_000181"
     CDS             780..4319
                     /gene="smc"
                     /locus_tag="VU722_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU1771247.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLHRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEATLKTLQDEMARLTESLEAIKFQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLATIARDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEQVAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKMQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            4316..5110
                     /locus_tag="VU722_000182"
     CDS             4316..5110
                     /locus_tag="VU722_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1771248.1"
                     /translation="MTIKLVATDMDGTFLDGSGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            5110..5928
                     /locus_tag="VU722_000183"
     CDS             5110..5928
                     /locus_tag="VU722_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1771249.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDDHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYTKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPNNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            5932..7221
                     /gene="ftsY"
                     /locus_tag="VU722_000184"
     CDS             5932..7221
                     /gene="ftsY"
                     /locus_tag="VU722_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU1771250.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDIEPAFTEAEEVS
                     QEEAEVESSEESVFQEEDSQDTVEENLDLEPVVEVSQEEVEEFPNSQEVTEEEKLEHE
                     GTIEENNSEVLEPETPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVTEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(7267..8754)
                     /locus_tag="VU722_000185"
     CDS             complement(7267..8754)
                     /locus_tag="VU722_000185"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU1771251.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKFFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(8903..9643)
                     /locus_tag="VU722_000186"
     CDS             complement(8903..9643)
                     /locus_tag="VU722_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1771252.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(9643..11808)
                     /locus_tag="VU722_000187"
     CDS             complement(9643..11808)
                     /locus_tag="VU722_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU1771253.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYQIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            11981..12934
                     /locus_tag="VU722_000188"
     CDS             11981..12934
                     /locus_tag="VU722_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1771254.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLTILISSVLFTLLHVGNAGLTPLS
                     LVNLFLFGVAMALYLLKIDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            13011..14999
                     /gene="uvrB"
                     /locus_tag="VU722_000189"
     CDS             13011..14999
                     /gene="uvrB"
                     /locus_tag="VU722_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU1771255.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            15009..15572
                     /locus_tag="VU722_000190"
     CDS             15009..15572
                     /locus_tag="VU722_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771256.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            15538..16047
                     /locus_tag="VU722_000191"
     CDS             15538..16047
                     /locus_tag="VU722_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771257.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            16100..16567
                     /locus_tag="VU722_000192"
     CDS             16100..16567
                     /locus_tag="VU722_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1771258.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYRHRTEDDWEKKIF"
     gene            complement(16564..17079)
                     /locus_tag="VU722_000193"
     CDS             complement(16564..17079)
                     /locus_tag="VU722_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU1771259.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALEQLGYLVKD"
     gene            complement(17091..17618)
                     /locus_tag="VU722_000194"
     CDS             complement(17091..17618)
                     /locus_tag="VU722_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1771260.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(17900..18463)
                     /locus_tag="VU722_000195"
     CDS             complement(17900..18463)
                     /locus_tag="VU722_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1771261.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(18447..18998)
                     /gene="coaC"
                     /locus_tag="VU722_000196"
     CDS             complement(18447..18998)
                     /gene="coaC"
                     /locus_tag="VU722_000196"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU1771262.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(19010..19699)
                     /gene="coaB"
                     /locus_tag="VU722_000197"
     CDS             complement(19010..19699)
                     /gene="coaB"
                     /locus_tag="VU722_000197"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU1771263.1"
                     /translation="MKILVTLGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEIQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            19930..21600
                     /locus_tag="VU722_000198"
     CDS             19930..21600
                     /locus_tag="VU722_000198"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU1771264.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRAVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVTKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            21928..23103
                     /gene="mutY"
                     /locus_tag="VU722_000199"
     CDS             21928..23103
                     /gene="mutY"
                     /locus_tag="VU722_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU1771265.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            23159..23863
                     /locus_tag="VU722_000200"
     CDS             23159..23863
                     /locus_tag="VU722_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1771266.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            23856..25205
                     /gene="vicK"
                     /locus_tag="VU722_000201"
     CDS             23856..25205
                     /gene="vicK"
                     /locus_tag="VU722_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU1771267.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            25207..26016
                     /locus_tag="VU722_000202"
     CDS             25207..26016
                     /locus_tag="VU722_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU1771268.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVNS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            26107..26349
                     /locus_tag="VU722_000203"
     CDS             26107..26349
                     /locus_tag="VU722_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU1771269.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            26351..26605
                     /locus_tag="VU722_000204"
     CDS             26351..26605
                     /locus_tag="VU722_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU1771270.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            26652..27428
                     /locus_tag="VU722_000205"
     CDS             26652..27428
                     /locus_tag="VU722_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU1771271.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS"
     gene            complement(27684..28670)
                     /locus_tag="VU722_000206"
     CDS             complement(27684..28670)
                     /locus_tag="VU722_000206"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU1771272.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            28864..31332
                     /gene="gyrA"
                     /locus_tag="VU722_000207"
     CDS             28864..31332
                     /gene="gyrA"
                     /locus_tag="VU722_000207"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU1771273.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDVVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQFLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            31332..32075
                     /gene="srtA"
                     /locus_tag="VU722_000208"
     CDS             31332..32075
                     /gene="srtA"
                     /locus_tag="VU722_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU1771274.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            32319..33116
                     /locus_tag="VU722_000209"
     CDS             32319..33116
                     /locus_tag="VU722_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU1771275.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            33264..34523
                     /locus_tag="VU722_000210"
                     /pseudo
     CDS             33264..34523
                     /locus_tag="VU722_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            34619..35893
                     /locus_tag="VU722_000211"
     CDS             34619..35893
                     /locus_tag="VU722_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU1771276.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            35903..36781
                     /gene="truB"
                     /locus_tag="VU722_000212"
     CDS             35903..36781
                     /gene="truB"
                     /locus_tag="VU722_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU1771277.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAIGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSQLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLSPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            37022..37324
                     /locus_tag="VU722_000213"
     CDS             37022..37324
                     /locus_tag="VU722_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU1771278.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            37432..38070
                     /gene="udk"
                     /locus_tag="VU722_000214"
     CDS             37432..38070
                     /gene="udk"
                     /locus_tag="VU722_000214"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU1771279.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            38198..39538
                     /locus_tag="VU722_000215"
     CDS             38198..39538
                     /locus_tag="VU722_000215"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU1771280.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            39516..39728
                     /locus_tag="VU722_000216"
     CDS             39516..39728
                     /locus_tag="VU722_000216"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU1771281.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            39725..40600
                     /locus_tag="VU722_000217"
     CDS             39725..40600
                     /locus_tag="VU722_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU1771282.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            40593..41408
                     /locus_tag="VU722_000218"
     CDS             40593..41408
                     /locus_tag="VU722_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU1771283.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMIQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            41401..41832
                     /locus_tag="VU722_000219"
     CDS             41401..41832
                     /locus_tag="VU722_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1771284.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            41839..43506
                     /gene="recN"
                     /locus_tag="VU722_000220"
     CDS             41839..43506
                     /gene="recN"
                     /locus_tag="VU722_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU1771285.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKINKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDNVTEAALTQARELLRNREK"
     gene            43508..44236
                     /locus_tag="VU722_000221"
     CDS             43508..44236
                     /locus_tag="VU722_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU1771286.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHEAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDSKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHYFIENDGFVAED"
     gene            44315..46138
                     /gene="lepA"
                     /locus_tag="VU722_000222"
     CDS             44315..46138
                     /gene="lepA"
                     /locus_tag="VU722_000222"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU1771287.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGDTYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPVINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPEPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNGKTFDVTEVGIFTPKAVDRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAESLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNQTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEE"
     gene            46551..47027
                     /locus_tag="VU722_000223"
     CDS             46551..47027
                     /locus_tag="VU722_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1771288.1"
                     /translation="MGLDHFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVYNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEPLYAYIAEAIA"
     gene            47066..47371
                     /locus_tag="VU722_000224"
     CDS             47066..47371
                     /locus_tag="VU722_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1771289.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGFDVHCDAVMVKDVN
                     EDLIKGYDIFTPIAATDLGFDPGIPVIEAGLILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            47419..48894
                     /locus_tag="VU722_000225"
                     /pseudo
     CDS             47419..48894
                     /locus_tag="VU722_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
     gene            48920..48997
                     /locus_tag="VU722_000226"
                     /pseudo
     CDS             48920..48997
                     /locus_tag="VU722_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            49145..50041
                     /locus_tag="VU722_000227"
     CDS             49145..50041
                     /locus_tag="VU722_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEU1771290.1"
                     /translation="MVIELKSEQLSVQFNSFGGALSSIKDAEGLEYLWQGDATYWSGQ
                     APVLFPICGSLREDTALYIDEKGQESKGKIPRHGLVRKKEFELVEQTDKSVTFAIEDD
                     ENSYQNYPYHFRLEITYSLTGKTVRTQYKIFNKETSKVMPYFIGGHPGFNCPLLDDEV
                     YEDYYLEFEKEETCSVPRPFPETGMLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDEL
                     QSRTIALRSRKHDKGVKVHFAEFPNLIIWSTLNKGPFIAFEPWSGLSTSLEEGDHLED
                     KKNVRLLEANQVEEIGFEIEVL"
     gene            50199..50624
                     /gene="lacA"
                     /locus_tag="VU722_000228"
     CDS             50199..50624
                     /gene="lacA"
                     /locus_tag="VU722_000228"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU1771291.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGRDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            50655..51170
                     /gene="lacB"
                     /locus_tag="VU722_000229"
     CDS             50655..51170
                     /gene="lacB"
                     /locus_tag="VU722_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU1771292.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            51181..52110
                     /locus_tag="VU722_000230"
     CDS             51181..52110
                     /locus_tag="VU722_000230"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU1771293.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTINRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            52112..53092
                     /gene="lacD"
                     /locus_tag="VU722_000231"
     CDS             52112..53092
                     /gene="lacD"
                     /locus_tag="VU722_000231"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU1771294.1"
                     /translation="MALTEQKHVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            53351..53968
                     /locus_tag="VU722_000232"
     CDS             53351..53968
                     /locus_tag="VU722_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771295.1"
                     /translation="MATKKSFKALVVGLGIVSIFSSALPMVSGSVFADSALTTVDKAN
                     DIVLNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEELSKNIGISVQE
                     ASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAGWHLKQFAVNPV
                     TSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            54366..55202
                     /locus_tag="VU722_000233"
     CDS             54366..55202
                     /locus_tag="VU722_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1771296.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            55238..55555
                     /locus_tag="VU722_000234"
     CDS             55238..55555
                     /locus_tag="VU722_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1771297.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            55555..57246
                     /locus_tag="VU722_000235"
     CDS             55555..57246
                     /locus_tag="VU722_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU1771298.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVVLAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            57418..58824
                     /gene="lacG"
                     /locus_tag="VU722_000236"
     CDS             57418..58824
                     /gene="lacG"
                     /locus_tag="VU722_000236"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU1771299.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGKKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQVIE"
     gene            58867..59115
                     /locus_tag="VU722_000237"
     CDS             58867..59115
                     /locus_tag="VU722_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU1771300.1"
                     /translation="MFKDFIQSIYEKVYIINFDKCSQIPCLTNEELKSLGKWYVYTGK
                     EWICHSDYELEEFKNIFLNFINPEEWDTISFDSDFMPF"
     gene            complement(59407..60168)
                     /locus_tag="VU722_000238"
     CDS             complement(59407..60168)
                     /locus_tag="VU722_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1771301.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIARFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFELSKLTKVIKP"
     gene            60347..60433
                     /locus_tag="VU722_000239"
                     /pseudo
     CDS             60347..60433
                     /locus_tag="VU722_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(60502..61464)
                     /gene="nrdF"
                     /locus_tag="VU722_000240"
     CDS             complement(60502..61464)
                     /gene="nrdF"
                     /locus_tag="VU722_000240"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU1771302.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNLGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDNDYNYGLD"
     gene            complement(61652..63811)
                     /gene="nrdE"
                     /locus_tag="VU722_000241"
     CDS             complement(61652..63811)
                     /gene="nrdE"
                     /locus_tag="VU722_000241"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU1771303.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLESMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYAKGSYFDKYITGEFVPKSERVKELFKDVFIPSAADWAELRDKVQ
                     ADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKKENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(63892..64110)
                     /gene="nrdH"
                     /locus_tag="VU722_000242"
     CDS             complement(63892..64110)
                     /gene="nrdH"
                     /locus_tag="VU722_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU1771304.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            64460..64723
                     /locus_tag="VU722_000243"
     CDS             64460..64723
                     /locus_tag="VU722_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU1771305.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            64729..66462
                     /gene="ptsP"
                     /locus_tag="VU722_000244"
     CDS             64729..66462
                     /gene="ptsP"
                     /locus_tag="VU722_000244"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU1771306.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFNEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            66597..67091
                     /locus_tag="VU722_000245"
     CDS             66597..67091
                     /locus_tag="VU722_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HEU1771307.1"
                     /translation="MSKEIDIEYYHQLALQKQKEHRKVLANLKKKPPKNLDKIAQQIH
                     QEVFEEIDCTACANCCKTLGPDFKEADITRIAKYFKMKLPAFEAEFLQVDEDGDKVFK
                     SMPCPFLGGDNLCSIYDVRPKACREFPHTDRKKIHQINHLTIKNTLTCPAAYLFVEKL
                     KDKL"
     gene            67149..67721
                     /locus_tag="VU722_000246"
     CDS             67149..67721
                     /locus_tag="VU722_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU1771308.1"
                     /translation="MPRPKTKEELVLASKENYDKLNRFISQLSEDELQTPFDFSKDQK
                     KKEAHWKRDKNLRDVLIHLYEWQQLLLTWVHSNQKGHERPFLPEPYNWKTYGKMNVTI
                     WKKHQKTSLEEATRLLEQSHREVLELMEGFSNDELFAKGIYKWTGGTSLGSYFVSSTS
                     SHYDWALKKIKAHQKNCKMQMDSLKKNEFF"
     gene            complement(67783..68772)
                     /gene="dhaQ"
                     /locus_tag="VU722_000247"
     CDS             complement(67783..68772)
                     /gene="dhaQ"
                     /locus_tag="VU722_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DhaKLM operon coactivator DhaQ"
                     /protein_id="HEU1771309.1"
                     /translation="MTFISNHKQKIISSYISATVSSHPELEKHPTLPLVYQKNRNPHQ
                     VPILSGGGSGHEPAHIGYVGEGMLTAAIYGQLFTPPTRTEILESIRFLNNGHGVFIIV
                     KNFEADIKEFSWAINTARQEGIKVGYSLAHDDISIEPHNRFQIRGRGLAGTILLHKVL
                     GYAAQNGADIEQLTDLGHELAPEIATIGFATKSASLPQATLPLFNLEEGNISYGIGIH
                     GEEGYRIVPFQSSEILANEIISKLRLHYHWKKGDQFILLVNNLGTTSNLEMGIFINDI
                     LQLLEIEGVTITFIKSGTFMTSLDMAGISVTLCPVKNKQWLKALNAPTTAFAW"
     gene            complement(68769..69299)
                     /gene="dhaS"
                     /locus_tag="VU722_000248"
     CDS             complement(68769..69299)
                     /gene="dhaS"
                     /locus_tag="VU722_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase transcriptional
                     activator DhaS"
                     /protein_id="HEU1771310.1"
                     /translation="MASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFY
                     NHFLDKYELLDWIFETDLTEYITNNLDFISGQKLLQELFLYFEQERDFYIQLFDIQGQ
                     NNFYDQFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSPV
                     PQPDFLIMTIIGKRPQ"
     gene            69453..70442
                     /gene="dhaK"
                     /locus_tag="VU722_000249"
     CDS             69453..70442
                     /gene="dhaK"
                     /locus_tag="VU722_000249"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEU1771311.1"
                     /translation="MKKIINKPTQVVDEMLQGLSFMHDDLVERLDGFDVIVRKVEKTG
                     KVGLISGGGSGHEPSHAGFVGDGMLSAAICGAVFTSPTPDQILEAIKAADEGAGVFMV
                     IKNYSGDIMNFEIAQELAEMEGIDVASVVVDDDIAVENSLYTQGRRGVAGTILVHKIL
                     GAAARSGKSLSEMKDLADKLVLEIKTIGLALSGATVPEVGKPGFILEDDEFEYGVGIH
                     GEPGYKKEKMQPSAQLASELVEKLSEGFQLKAGERYGLLINGLGSTPLMEQYVFANDV
                     AKLLHEKGVELSFKKIGNYMTSIDMAGLSLTLIRLANDEWLDALNAPVTTPAW"
     gene            70464..71039
                     /gene="dhaL"
                     /locus_tag="VU722_000250"
     CDS             70464..71039
                     /gene="dhaL"
                     /locus_tag="VU722_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEU1771312.1"
                     /translation="MNAEQALEWMKLFNEKIQEQKDYLSELDTPIGDGDHGGNMARGM
                     AAVMENLEGKQFETSSDVFKVVSMQLLSKVGGASGPLYGSAFMGMSKADSHSKLEEIL
                     QSGLDMIVKREKAVVGEKTMVDVWTPAIAALSDGQLTHELIDKVVNATKDLLATKGRA
                     SYVGERSLGHIDPGSFSSGLLFTAILETGVV"
     gene            71039..71413
                     /locus_tag="VU722_000251"
     CDS             71039..71413
                     /locus_tag="VU722_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU1771313.1"
                     /translation="MESIGLVIVSHSKNIAEGLVELISEVAKDVPITYVGGTEDGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLEMVADFSDKSIMINRVPIVEGAYTAAA
                     LLQAGAELSVIQTQLSELEINK"
     gene            71861..72574
                     /locus_tag="VU722_000252"
     CDS             71861..72574
                     /locus_tag="VU722_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU1771314.1"
                     /translation="MSYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQGKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIDRDYDLYAATNGITAIQTGRLAQSGLEPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVH
                     SYQDLLDCLDKNILEKITF"
     gene            72588..73037
                     /locus_tag="VU722_000253"
     CDS             72588..73037
                     /locus_tag="VU722_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771315.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNETVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLNCKKWFR"
     gene            73083..73736
                     /locus_tag="VU722_000254"
     CDS             73083..73736
                     /locus_tag="VU722_000254"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU1771316.1"
                     /translation="MEHSSWHALIKEQLPKGYFGKINQFMEQVYAQGTIYPPKEKVFQ
                     ALLTTPLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAVQANGHAGQIWEPFTDAVIQVVNQLDKPVVFILWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANALLKETGQEPIDWLR"
     gene            73746..74210
                     /locus_tag="VU722_000255"
     CDS             73746..74210
                     /locus_tag="VU722_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1771317.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            74223..75491
                     /locus_tag="VU722_000256"
     CDS             74223..75491
                     /locus_tag="VU722_000256"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU1771318.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQEVLQSAAKDKINVKTVATITKNFNGQDLTDFKALLEVGAVGFSDDGIPLESSKVV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAKEHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAQVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPSKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            75505..75765
                     /locus_tag="VU722_000257"
     CDS             75505..75765
                     /locus_tag="VU722_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771319.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPASNRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            75776..77137
                     /gene="pdrM"
                     /locus_tag="VU722_000258"
     CDS             75776..77137
                     /gene="pdrM"
                     /locus_tag="VU722_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU1771320.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            77291..78259
                     /locus_tag="VU722_000259"
     CDS             77291..78259
                     /locus_tag="VU722_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU1771321.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRCMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESVFEDIYAD"
     gene            78275..79242
                     /locus_tag="VU722_000260"
                     /pseudo
     CDS             78275..79242
                     /locus_tag="VU722_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
     gene            79459..80502
                     /locus_tag="VU722_000261"
     CDS             79459..80502
                     /locus_tag="VU722_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU1771322.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYSEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            80566..82251
                     /gene="lpdA"
                     /locus_tag="VU722_000262"
     CDS             80566..82251
                     /gene="lpdA"
                     /locus_tag="VU722_000262"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU1771323.1"
                     /translation="MPKVGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYRVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPVMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIATKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            82319..82675
                     /locus_tag="VU722_000263"
     CDS             82319..82675
                     /locus_tag="VU722_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU1771324.1"
                     /translation="MMKYIFSEEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFT
                     SGKVEVFANVTESKIQDIKIYGDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITR
                     YFAGISREEIAEAVVG"
     gene            complement(82741..84018)
                     /gene="ltrA"
                     /locus_tag="VU722_000264"
                     /pseudo
     CDS             complement(82741..84018)
                     /gene="ltrA"
                     /locus_tag="VU722_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(84719..85789)
                     /gene="xerS"
                     /locus_tag="VU722_000265"
     CDS             complement(84719..85789)
                     /gene="xerS"
                     /locus_tag="VU722_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU1771325.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDLVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(86373..87923)
                     /locus_tag="VU722_000266"
     CDS             complement(86373..87923)
                     /locus_tag="VU722_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU1771326.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(87939..88718)
                     /locus_tag="VU722_000267"
     CDS             complement(87939..88718)
                     /locus_tag="VU722_000267"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU1771327.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(88705..89556)
                     /gene="ylqF"
                     /locus_tag="VU722_000268"
     CDS             complement(88705..89556)
                     /gene="ylqF"
                     /locus_tag="VU722_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU1771328.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTCALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(89816..94930)
                     /locus_tag="VU722_000269"
                     /pseudo
     CDS             complement(89816..94930)
                     /locus_tag="VU722_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(94979..100195)
                     /locus_tag="VU722_000270"
     CDS             complement(94979..100195)
                     /locus_tag="VU722_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEU1771329.1"
                     /translation="MEKYFGEKQQRFSFRKLSVGLVSATISSLFFMSVLGSSSVEAQE
                     TQETKGVHYKYVTESELSSDEKKQLVYDIPTCMENDDETYYLVYKLNSQNQLGELPNT
                     GSKNDMKTLVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSAHALENN
                     LLLNYNTDYELTTGEKLPLPKEISGYTYIGYIKERNITSESKVNNQEKSVDTSKNQQK
                     VDYTIAPNFIESPSKIQVINGQYETVPEFRDGQVGAVATESAATKADTLSSDMNSEVE
                     SHSIPPTVDSSQNGENLGKQGEDATPVEKPKEQEPEKTEEVPVNPTEGTTEGTSNQGA
                     KNPVQPAEESTTNSEKISPDTSNENTGEVSSNPSDSKPPVEETNKPEKDESKDETSTK
                     PENSAHPITESGQTEPDQPKGNSPEDVSTESKTSNSNESEEIKHKTEVEPDKKVEEQE
                     KTIELRSVSDVELYSYEGNQSKQHTSLDKVPDNKSAYFIKVKSAKFKDVLLPVSNIED
                     TTKDGKAVYKITARLEHLKQSVDNQYQDNFTYYLPKLVQNDSPIYTSFKKLITDMNSR
                     PSGTFTLGATMNAREFELNENQESYVTSKFTGTLIGSHQGKHYAIYNLKKPLFNTLNN
                     ATIQNLTLKDVNISGKNHVASVAKEATNSSTLDNVHANGIIAGELGIGGLVQKVDNST
                     ISNSSFTGRITNTFVTTSQYAIGGLVGQLTGTNASVDRSIATVTISSNAEYSNQTIGG
                     IAGIVENNATVQNSYAEGEINNVKPFARVGGVAGSLWTNGSSTEDNSGILQNVLSDMN
                     ITNGNAISGYHFNGMKKKAVYSNKDNKVVNVQAVGDEVMSIDSTVERGTEIEKTAVQA
                     KKEQITKKHTITVEDFTNSVKQDVDYTKATHYQVARDIAYKNIEKLLPFYNRDTIVKY
                     GNQLSTDHNLFKKELLSVVAMKNEEVVSDITSNKNSINHLLLHYKDGTSEKVNVTYHS
                     DFANLAEYTIGTTGLVYTPNAFLKDYTSIIDRVKNDLNTVQYDPTSLKNLLGISDNVK
                     LTELYLDEQFAKTKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLT
                     YLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPLDTIIELGKSGYNNLLAKNNVVTYN
                     ALLTNNYGTKDLFSALEGYRKAFAPTQTNNDWFKSQTKAYIVEEKSNILEVKANQEKA
                     GSKYSIGVYDRITSDSWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNKEHQA
                     SGDLNSFVEENARETAKRQRDHYDYWYRILDEKEREKLYRNILLYDAYKFGDDHTEGK
                     AKKVATFDDPNPAMQHFFGPVGNKVGHNEHGAYATGDAVYYMGYRMLDKDGAITYTHE
                     MTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPNDATITINSILKHSKSDSTEGQ
                     RLQVLDPTTRFNNADDLKQYVHNMFDVIYMLEYLEGKSIISQLSATEKMTALRKIENK
                     YVKDREDGNEVYATNVVQNLTEEDAKKLTSFENLIDNNILSAREYKSKEYERNGYFTI
                     KLFAPIYAALSSDIGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEVAKQNGKKI
                     TIYGKERGLVTDELVLQKVFNGQYETWTEFKKAMYNERVAQFDRLNKVTFNDTTQPWQ
                     TFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNPDIDSEVHKLKKAIFKAYLDQT
                     DDFRSSIFENKK"
     gene            complement(100434..101612)
                     /locus_tag="VU722_000271"
     CDS             complement(100434..101612)
                     /locus_tag="VU722_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771330.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTKKV
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFSPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERVYQDYFGFTETLTQEERKWAKIFFGKNRTERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNPYFRELPEEKSRLARLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKESLQADHLSSAQESWIEGILLNCIKPFLERLVI
                     "
     gene            complement(101630..105280)
                     /gene="addA"
                     /locus_tag="VU722_000272"
     CDS             complement(101630..105280)
                     /gene="addA"
                     /locus_tag="VU722_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU1771331.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGHGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQTFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILEKFPQVREAYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAKNPHEGKLILLKENFRSSSEVLSATNDVFEGLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKVEFLLYDKDDTGEEEEGQAETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIGMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKEYPAAK
                     NGKLNSTTRLQARNFQDWLWAVSKVFTKDKLNFSYRFVGEDQLTREAIGELKTKSPLQ
                     DSSQADNRQSETIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVDKKISFDLPDFSSKEKVTGAEIGSATHELMQRIDLSQQPTLASLTETLK
                     QVQTSPAVRDKINLAKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYEGRIVLFDYKTDRYDEPSQLIDRYRGQLALYGEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(105277..108552)
                     /gene="rexB"
                     /locus_tag="VU722_000273"
     CDS             complement(105277..108552)
                     /gene="rexB"
                     /locus_tag="VU722_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU1771332.1"
                     /translation="MKLLYTDIRTSLTEILTRKAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLRYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLIAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(108752..108910)
                     /locus_tag="VU722_000274"
                     /pseudo
     CDS             complement(108752..108910)
                     /locus_tag="VU722_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            109081..109725
                     /locus_tag="VU722_000275"
                     /pseudo
     CDS             109081..109725
                     /locus_tag="VU722_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            109825..110034
                     /locus_tag="VU722_000276"
                     /pseudo
     CDS             109825..110034
                     /locus_tag="VU722_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            109934..110383
                     /locus_tag="VU722_000277"
     CDS             109934..110383
                     /locus_tag="VU722_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1771333.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSSLQRANERLKKPIPKHLSPHIFRHTTISILSE
                     NKIPLKTITDRVGHSDSEVTTSIYTYVTKNMKDEAINVLDKVMKKIF"
     gene            complement(110521..111825)
                     /gene="eno"
                     /locus_tag="VU722_000278"
     CDS             complement(110521..111825)
                     /gene="eno"
                     /locus_tag="VU722_000278"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU1771334.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            111989..112435
                     /locus_tag="VU722_000279"
     CDS             111989..112435
                     /locus_tag="VU722_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU1771335.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(112432..113547)
                     /locus_tag="VU722_000280"
     CDS             complement(112432..113547)
                     /locus_tag="VU722_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU1771336.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVEYLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGSGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(113556..>113771)
                     /locus_tag="VU722_000281"
     CDS             complement(113556..>113771)
                     /locus_tag="VU722_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU1771337.1"
                     /translation="KKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAK
                     EVLKKEIPHHVDKRDFLEVLPLIDRLE"
BASE COUNT        33974 a        21213 c        24031 g        34553 t
ORIGIN      
        1 ccaaatcccc tccagtcccg ttttaaagtg actcaggggg ctttttttga tataataaaa
       61 aggactgtta tcagttagaa agaggttagt atgaaagaat tacaaactgt actaaagaat
      121 cattttgcaa tcgaatttgc agacaaaaat ttactggaaa ctgcctttac tcatacgagt
      181 tatgccaatg agcaccgcct cttaaaaatt tcacacaatg aacgcttgga atttttagga
      241 gacgctgttc tacagttatt gatttcagaa tatctatata aaaaatatcc taaaaagcct
      301 gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt
      361 gcgcgtgatt gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatctggt
      421 ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt
      481 ttggataagg atgtggccaa ggtcaaggaa tttatctacc aagttatgat tcctaaggta
      541 gaagcaggcg agtttgagat gattacagac tacaaaaccc atctccaaga gttacttcag
      601 gtcaatggtg atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat
      661 aaggtctttg atgtagaagt tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt
      721 tctaagaaat tagcagagca ggaagctgcc aaaaatgccg ttgagaaagg gctggattca
      781 tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg
      841 tttttgacca aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta
      901 cagaaagtct gcgttgggcc ttgggggagt caagtgtcaa gagtctccgt gggggcaaga
      961 tgccggatgt catctttgct gggaccgaaa gtcgcaaacc gctcaattat gcttctgtag
     1021 ttgtgactct ggataatcat gacggattta tcaaggatgc aggccaagaa atcagggtag
     1081 aacgccatat ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc
     1141 tgcgtgatat tcatgacctt ttcttggata caggtttggg acgagattcc ttctctatca
     1201 tttcccaagg gaaggttgag gagattttta attctaagcc tgaggaacgc cgagctattt
     1261 ttgaagaagc tgcaggagtt ttaaaataca agactcgcag aaaagaaact gagagtaaac
     1321 tgcaacaaac tcaggataat ctagaccgct tagaggacat tatctacgag ttggataatc
     1381 aaatcaagcc tcttgagaag caagctgaga atgcccgtaa gtttttagac ttggaaggac
     1441 aacgtaaggc tatttattta gacgttctgg ttgctcaaat caaggaaaat aaggcagaac
     1501 tagagtcgac agaagaagag ctggctcagg ttcaagaact cttgatgagt tattaccaaa
     1561 agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg
     1621 ctgaaatggc caaagaccaa ggcagtttga tggacttgac tagtctgatt agtgatttag
     1681 aaagaaaatt agccctatcg aaactggagt ccgagcaagt ggccctgaat caacaggagg
     1741 cacaagctcg tttggctgct ttggaggata agagaaattc actcagcaaa gaaaagtatg
     1801 ataaagaaag ctctttagct ctgttagagg gaaatctagt ccaaaataat caaaaactcc
     1861 atcgtttaga agctgaattg ctggctttct cagacgatcc tgatcagatg attgagctct
     1921 tacgtgaacg ctttgtagct cttttacaag aagaagcgga tgtctcaaac cagttgaccc
     1981 gtattgagaa tgagttggaa aatagtcgtc agctttctca aaaacaagca gatcaactag
     2041 aaaagctgaa agagcaattg gctatagcta aagagaaggc tagtcagcaa aaggaagagc
     2101 ttgaaactgc caaggagcag gttcagaaat tattggctga ctaccaagct attgccaagg
     2161 agcaagagga gcagaaaact tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg
     2221 ataatctcaa aaacaagcag gccagagctc aaagtttgga aaatatcctg agaaatcata
     2281 gtaactttta tgcaggtgtt aagagtgttc tccaagaaaa agatcgccta ggtgggatta
     2341 ttggtgcagt cagtgagcat ctgacctttg atgtttatta tcaaactgcc ctagagattg
     2401 ccttaggggc aagtagccag catatcatcg tagaagatga agagtcggca accaaagcta
     2461 ttgatttcct taaacgaaac agagccggtc gtgcaacctt ccttccgttg acaacaatca
     2521 aggctcgtac gatttctagc cagaatcaag atgctatcgc tgtaagtcca ggtttccttg
     2581 ggatggcaga tgagttggtg acttttgata ctagactgga agccattttc aagaacttgc
     2641 tagctacgac ggctatcttt gataccgtag aacatgcgcg tgcagcagct cgccaagttc
     2701 gttatcaggt tcgtatggtg acattggatg ggacagagtt gcgcacaggt ggttcttatg
     2761 caggtggtgc caatcgccag aataacagca tttttatcaa gccagaactg gagcaattac
     2821 aaaaagaaat tgctgaagaa gaagcaagct tgggttcaga agaggcgact ttgaagacct
     2881 tgcaagatga gatggccaga ttgaccgagt cattagaagc tattaaattt caaggagagc
     2941 aggcacgtat tcaggagcaa ggcttgttcc tcgcttatca gcaaactagt cagcaagttg
     3001 aagaactgga aactctttgg aaactccaag aagaggaaat agatcgtctt tccgagggag
     3061 attggcaagc ggataaggaa aactgccaag agcgccttgc tacaatcgcc agagacaagc
     3121 aaaatctgga agctgagatt gaagagatta agtccaacaa aaatgccatc caagaacgct
     3181 atcagaactt gcaagaacag gtagcgcaag ctcgtttgct taagacagaa ctgcaagggc
     3241 aaaaacgtta tgaagttgct gatattgagc gtttaggcaa ggaattggat aatctggata
     3301 tcgaacaaga ggaaatccag cgccttcttc aagaaaaggt tgacaatctt gagaaagttg
     3361 atacagaatt gctcagtcaa caggcggaag aagccaaaat gcagaaaaca aacctccaac
     3421 aaggtttgat tcgcaagcag tttgagttgg atgatattga aggtcaactg gatgatattg
     3481 ctagtcattt ggatcaggct cgccaacaga atgaagagtg gattcgcaag caaacacgtg
     3541 ctgaagccaa gaaagaaaag gtcagcgagc gcttgcgcta tttacaaagt caattaacag
     3601 accaatatca gattagctat actgaagctc tagaaaaggc gcatgaattg gaaaacctca
     3661 atctggcaga gcaagaggtg caggatttag agaaagctat tcgctcactg gggcctgtca
     3721 atatagaagc tattgaccag tacgaagaag ttcacaatcg tctggatttc ctaaatagcc
     3781 aacgagatga tattttgtca gcgaaaaatc tgctccttga gaccattaca gagatgaatg
     3841 atgaggtcaa agatcgcttt aaatcaacct ttgaggccat tcgtgaatcc tttaaagtga
     3901 ccttcaaaca gatgtttgga ggaggtcagg cagacttaat cttgactgag ggagacttgt
     3961 tgacagctgg ggttgagatt tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc
     4021 tcatgagtgg tggtgaaaaa gccttatcag ctcttgcttt gcttttttct atcattcgag
     4081 ttaagactat cccatttgtc atcttggatg aggtagaggc tgcgctggac gaagccaatg
     4141 ttaaacgttt tggggattac ctcaaccgct ttgacaagga cagccagttc atcgtcgtaa
     4201 cccatcgtaa gggaaccatg gcagcggctg attctatcta tggagtgacc atgcaagaat
     4261 cgggggtctc aaaaattgtt tcggttaagt taaaagattt agaaagtatt gaaggatgac
     4321 aattaaacta gtagcaacgg atatggacgg aaccttccta gatgggagtg ggcgctttga
     4381 tatggatcgt ctcaagtctc tcttggcttc ctacaaggaa aaagggattt actttgcggt
     4441 ggcttcgggt cggggatttc tgtctctgga aaaattattt gctggtgttc gtgatgacat
     4501 tattttcatc gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc
     4561 gactatgtct cgtgactttt atctggcaac ttttgaaaag ctgaaaacgt caccttatgt
     4621 agatatcaat aaactgctct tgacgggtaa gaagggttct tatgtgctag atacggttga
     4681 tgagacctat ttgaaagtga gtcagcacta taatgaaaat atccaaaaag tagcgagttt
     4741 ggaagatatc acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaactcttga
     4801 agctggggaa gcttgggtaa acgaacatgt tcctggtgtt aaggccatga caactggctt
     4861 tgaatccatt gatattgttc tggactatgt tgataagggt gtggctattg ttgaattagc
     4921 taaaaaactt ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt
     4981 acatatgatg caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt
     5041 agaattagca aagactgtga ttggtcacca taaggaccag tcggttatag cttatatgga
     5101 gggcttataa tggcagatat aaaattaatc gcattggact tggacggtac cttgctgact
     5161 actgataaaa ggctgacgga tcgcaccaag gcaactttga aagctgcgcg tgatcgtggt
     5221 atcaaggtcg tattgacaac tggtcgtccc ttaaaagcca tggatttctt tctccatgag
     5281 ctaggaactg acgaccacga agatgagtat acgattactt ttaatggtgg tttagttcag
     5341 aaaaatacag gagaaatcct tgataaaaca gtcttttcat atgatgatgt ggcacgtttg
     5401 tatgaagaaa cagagaaatt atcactgcct cttgacgcta tctcagaagg aactgtttat
     5461 caaattcaat cggaccaaga aagtctttat accaaattca atccagcctt gacctttgtt
     5521 ccagtggact ttgaagactt atctagtcaa atgacctaca acaaatgcgt gactgccttt
     5581 gctcaagaac ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat
     5641 gaaatcttta aatcacgtga aatgttgcta gaatggtcac caaataatgt tcataaagca
     5701 acaggtttgg caaaactaat cagtcatctt ggaatcgacc aaagccaagt gatggcttgt
     5761 ggtgacgagg ccaatgacct ctctatgatt gaatgggcag gtctcggtgt tgccatgcaa
     5821 aacgctgttc ctgaagtcaa ggcagtcgca aatgtggtaa ctcctatgac caatgatgaa
     5881 gaagctgtcg cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggatta
     5941 tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct
     6001 ctggaaaatc ttgatttgtc tgaagatatt gagcctgcct tcacagaagc tgaggaagtt
     6061 tctcaagaag aagcagaggt tgaaagttct gaagaatctg tgttccaaga agaggatagt
     6121 caagacacag tcgaagaaaa tctggattta gagccagttg tagaggtttc tcaagaagaa
     6181 gtagaagaat ttccaaactc acaagaagtc acagaggaag agaagcttga gcacgaagga
     6241 actatagaag aaaataattc tgaagttctt gaaccagaaa ctcctcaaac agaagaaact
     6301 gttcaggaaa aatatgaccg cagtcttaag aaaactcgca caggtttcgg tgcccgcttg
     6361 aatgccttct ttgctaactt ccgctctgtt gacgaagaat ttttcgagga actggaagaa
     6421 ctgctgatta tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga ggaactacgt
     6481 tacgaagcca agcttgaaaa tgcgaagaaa cctgatgcac ttcgtcgtgt catcattgag
     6541 aaattggttg agctttatga aaaggatggt agctacgatg aaagcatcca cttccaagat
     6601 aacttgacag ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac ttctatcgga
     6661 aaactagccc accgctacaa acgagctggt aagaaggtca tgctggttgc agcagatacc
     6721 ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc gacgagtaga tgttccagta
     6781 gtaactggac ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc
     6841 gtggctgaag gtatcgatat tctcatgatt gatactgctg gtcgtctgca aaataaggat
     6901 aaccttatgg ctgagttgga aaagattggt cgtattatca aacgtgttgt gacagaagca
     6961 ccacatgaaa ccttcttggc acttgatgca tcaacaggtc aaaatgccct agtacaggcc
     7021 aaagaatttt cgaaaatcac acctttaacc ggaattgttt tgactaagat tgatggaact
     7081 gctcgaggag gtgtggttct agccattcgt gaagaactca atattcctgt aaaattgatt
     7141 ggttttggtg aaaaaatcga tgatattgga gagtttaact cagaaaactt tatgaaaggt
     7201 ctcttggaag gtttaatcta atcagaagca aaaatcctgc aaggcataaa cttgcaggaa
     7261 atttttttat tcgaaacgac catcttgacg ataggcgata tccggttgcc aagtccattt
     7321 ggcaccgaat ttttcaagta ggtcaaagct ggcttgaggt cccatgcttc cagctttata
     7381 gtcatgaagt ggggcaccat tttcagccca gagcttttca atacggtcaa tcaacttcca
     7441 tgacgcacca acttcatccc agtggctaaa gttagttgag ttgttattta ggacatcata
     7501 aatcaatttt tcgtatggtt ctggagaagc accagttgca gtcgcatctg tacggtaatc
     7561 aagtgagtta ggagccaagt taaattcttc tcctacttgc ttcccattta ggctaagaga
     7621 gaagccttct gttggttgaa tatagatagt caaaatattt ggagcaagtg gttctccaaa
     7681 gatagaatcc atttgtttaa agacgatgtt gacatgagtt cctttttcag tcagtcgttt
     7741 acctgtacgg aaaaagaaag gaacactacg gaatcgatcg ctgtctacaa agaaggcacc
     7801 agatgtaaag gtttcagttg ttgattctgg attcacattt ggctcgctac gataagagat
     7861 gtatttcatg ccatcaatct taccagagcg gtattgccca cggataaagt gttctttgag
     7921 ttcttcatca gttggatgat agaggttttt aaagacctta atcttttcag cacgaatctc
     7981 gtcttttgtg aagcttgctg gtttgtccat ggcgaggagc gaaagaagtt gtagagtgtg
     8041 gttttggacc atgtcacgga gggcaccgga ttggtcatag tagccaccac gttcttctac
     8101 acccaagcgc tccgcaaagg taatttgaac attgtcgata aaatccttgt tccaaacgtt
     8161 ttcaaaaatc aagtttgcaa agcgaactgc aaagatgctt tggatcattt ccttaccaag
     8221 ataatggtcg atacggaaaa tttgttcttc gtcaaatgtt gctaggagtt cgtcattcaa
     8281 cttgcttgca gttgcgtaat ctgtaccaaa tggtttttca acgatcaagc gctcaaaacc
     8341 tttgccatcg acaatgtttt cagatttgag gtgtttggca atggttccaa agaactgagg
     8401 tgccatagac aagaagaaga acttattgtg ttcagcttgg tatttttcat taagctcagc
     8461 ttgtaattga cgcaaagcaa tataatgttc cgaatcattg acatcatggc tttgatagta
     8521 gaagtggcta gcaaattctt gggcttgctc ggtactatct gccaaatcaa ggatggactc
     8581 gacaactaca gattcaaaat attccttact ccaaggtcta cgggcagttc caataacggc
     8641 aaagtgcttg gaaagattgc cggatttata taatctaaaa agggaagggt agagcttgcg
     8701 tttagccagg tctccactcg caccgaaaat tgtaacaata accttagatg acatctagct
     8761 acctaatttc tatttttatt cctagtcttg ctaggtatga ggaaacctca tttcataaac
     8821 ttaattctaa cataattttc cgaaaaatca aaaattccaa tacgaggtag aaaaactgca
     8881 aggaaatcct tacagtttga gtttagacgt ttaagacctt atctaagaac tctttcagac
     8941 gagggtgttg tgggttatca aagatttggt caggtgttcc gtcttcaagg aactcgccat
     9001 ctgcagtaaa gataacgcgg ttggcaacct gacgagcaaa tcccatctca tgggttacga
     9061 taatcatggt catgccttgc tcagccaatt ccttcataac gttaagtacg tctccaacca
     9121 tctcagggtc aagggcagaa gttggttcat cgaagagcat gatgtctgga ttcattgcta
     9181 ggccacgagc tatggccaca cgttgttttt gaccacctga taggctatct ggattggcat
     9241 tagctttatc tgctagtcca accttttcaa gcaactccat tcccaatttc tcagcttctt
     9301 ccttagtcat caacttgtgc tcaataggag caaaggtgat gttgtccaat acagacatat
     9361 gagggaagag gttgaagtgt tggaatacca tgccgatatt ttcacggacg tggtcaacat
     9421 tggttgtttt ttcagttaaa tcatagccgt tcacagtgat gtgaccgcta gtgacttctt
     9481 ctaaaagatt gaggctacgg aggaaagttg acttaccaga acctgaagga ccgatgatac
     9541 aaacaacatc tccttcatag aacttagtcg taattccttt taggacttca ttttttccat
     9601 agtgcttgtg taaatcattt acatcaattt ttaattttgc cattaacgaa tcctcttttc
     9661 taagcgtttc gctagtctag tcaaaagtgt gataattaca agatagaaga tagcaaggat
     9721 tgcatacatc ttgaaacttt ggtagttacg agcaatgata atcttaccag tttggaagag
     9781 ttcaaccaaa ccgatagcag atacgatagt tgtatcttta agagcgataa cgaattggtt
     9841 gacaaagttt ggcaacatca atttagttgc ttgtggcaag ataatcttac gcatggtttt
     9901 tccataagag atacccaagc ttcggctggc ttccatttgg ccaactggaa cggcctgaat
     9961 accaccacga acgatttcag cgatataagc agccgcattg agtgagaggg caatggttcc
    10021 agctacaaag tcgttaattg ggctttgttg gcctgtgata gactcgatga agtttggaat
    10081 cccccagaag atgaaggctg caagaatcat caatggaata ccacgaataa cgtcaacgaa
    10141 aatctcagag atgactcgaa gagatttgta tgggctaacg ctaaacatac cgaagataat
    10201 tccgatgaca atggcaatag caaatgagat aagagctaga gcaagagtga taccaagacc
    10261 gctaaggagt tgtttgtagt tgttttgaag caagccccag agcgttgttt cgtcaacagt
    10321 acttgttgaa gcagttgaag attcgctagc taggtatttg tcaagaatct tttggaattc
    10381 accgtttgct ttaaggtttg caagtccgtt gttgaacatt tcaatcagtt ctggatttgc
    10441 tcctttttta acggcaaagg ctgtttcacc gattggagtt ccagagattg gagttttcaa
    10501 tttttgacct tggctgatag aatatttgag aacaggttca tcatccataa cagcatcaat
    10561 ggcaccagtg tttaaactgt catacattga tgaaccatca gcgaaggttt taatttgata
    10621 accgtatttg ctttgatttt ctgttaggaa ggtttgagaa gcagttccgt ttttaacacc
    10681 gactgtcttt ccttttagat cttcataaga agcaatattg cttgattctt tgacaccaag
    10741 aatggtatta gcagtgtagt atgattctga gaagtcaaaa gttgccttac gagcatctgt
    10801 gacagacata ccagcaatga taccatcggc ttgaccagct tggacagcac tgatagcagc
    10861 atcaaaacca gggttggtga tttcaatttc aaaaccttgg tctttagcga ttgccttaat
    10921 caattccata tcaataccag tgtattggtt gcttgaattt tggaaaacaa aaggtgcaaa
    10981 agaagaatcg ctggcaatga tatatttagc cttaacagga atagctttta atcctgctag
    11041 agtagttgta gttggcactg ctgaagatga tgaagcagtc catttcttga taattttatc
    11101 aagactacca tcttttttca tttcagccaa ggcttggtta aattcagtaa ccaggtgctc
    11161 gtatttactt ccttttttca caccgaaagc aaaacttcct acagcttcac catccatttc
    11221 aatatggagg tcttgacctt ggttaatggc atattcgata acaggtttgt catccatcat
    11281 ggcatcgatg gcaccagcac tcaagctgtt attcattaaa tcaccagtgt caaatgtttt
    11341 aatagtaaag ccgtatttat ctttgattgt ttcaaggaaa cgttgagcgg cagttccgtt
    11401 tttaacacca acggttttgc cagttaattg gtcgtacttg ctaattttgt gtgactttgt
    11461 agtagcaatg acaacttttg tatcatagta agtatcagac atggtgaaga ctttttcacg
    11521 ttctttagtc tttgtcatcc ctgccatgat agcgtcggct tgcccagctt gaaccgcatt
    11581 gactgctgcg tcaaatccag gataggacat ctgaatgttc cagcctttaa tctcagcgac
    11641 tttgttaata atgtcaacat caattccttt ataagtttga tctgaatctt taaactcaaa
    11701 aggtgcatag gcggtatcag aaacaatctt aatcgtttct gctttggcaa tacctagtga
    11761 gaaaattggg aataaaatta gcaaaaatgc tagaaatttt ttcttcattt ttagtctcct
    11821 tttccgaata ttctctcatt atatcagaaa aagtaaaaaa aggcaaattt ttatattttt
    11881 cgtgtcagaa aatataacat tgatttttcc ttttctttct tgaattgcta ttaaaaagtg
    11941 ctataataat agtgtatata gaagaaaaga ggacggggat atgaagaaca aaagaatatt
    12001 taaagacttc caagcttcaa aaatgagttt aaacatttac acaagcccct tgttagcctt
    12061 tgtttttgtc ttcataggag agtttgtggc ttatacttta tatggtatta gtttgttagc
    12121 tctcatcgga cttgctagaa attttggaga ggccggtcaa aatcttgcaa gctacttgca
    12181 gaccttgcat cagagcttga cggataaaac aagtgatttt cgtttaattt taggattact
    12241 ggcctttggt tttattctta acactgtgtt cagatggaca agaaaagttg agaaaagacc
    12301 tattcgaacc ttgggatttt atagagagaa ttgcctcagc aatcttctga aaggatttag
    12361 tctaggcctg gcactttttc ttctgacctt gttaggttta gtggtcttag gtcaatatcg
    12421 tttggaatcc attcacttga atccttattc tcttgccttt gtcgtcttta ctatcccatt
    12481 ttggatttta caggggacag cagaagaagt ggtggcccgt gcttggctac ttcctcaatt
    12541 ggcctcaaga accaatctaa aacttactat tcttatatct agcgtacttt ttactctgct
    12601 tcatgtgggg aatgcaggtc tcacccctct atctctagta aatctctttt tattcggagt
    12661 tgccatggct ctttaccttc tcaaaattga tacagtttgg ggtgttgcag gtattcatgg
    12721 tgcttggaat tttgctcagg gtaatctctt tgggatttta gttagtggtc aaccgtcagg
    12781 aacgtctctg atgacctttt taccacaagg caatcaagat tggctatcag gtggttcttt
    12841 tggcatagaa ggttccatta tgacaagtct ggtattacta ctgctgattg tctatcttgc
    12901 taataaatta aagaaagaaa atgaaaggat gtgacttcgg tccgtccttt tcttcgtgaa
    12961 aatactataa gtatgctaaa ataggaatag cacatggaga gaggattctt atgatcaatc
    13021 acattacaga taatcaattt aaactagtat caaaatatca accatcagga gatcaacccc
    13081 aagctatcga gcagttggtg gataacattg aggggggaga aaaagctcag attctgatgg
    13141 gggcgactgg aacagggaag acctatacta tgagtcaggt catttctaaa gtcaataaac
    13201 caactctggt tattgcccac aataaaactc tggctggtca gctctatggg gagtttaagg
    13261 aatttttccc tgaaaatgca gttgagtatt tcgtatccta ctatgattat taccagccag
    13321 aggcctatgt cccttctagc gatacctata ttgagaagga tagttctgtc aatgacgaga
    13381 ttgacaagct tcgccactca gctacctcag cccttttgga gcgtaatgat gttattgtcg
    13441 tggcctcagt ctcttgtatc tatggtttgg gttcgcccaa ggaatacgct gatagtgtcg
    13501 ttagtctccg tcctggtcta gagatttctc gtgataaact cttgaatgac ttggtcgata
    13561 ttcagtttga acgtaatgat attgatttcc aacgcggaag atttcgcgtt cgtggggatg
    13621 tggtagagat tttcccagct tcccgagatg aacatgcctt tcgagtagaa ttttttggag
    13681 acgaaattga ccgtattcgt gaagttgagg ctctgacagg tcaggtgttg ggagaagtgg
    13741 atcatttagc gattttccca gcgacacact ttgtgaccaa tgacgaccac atggaagttg
    13801 ccattgcaaa gattcaggcc gagttggagg agcagttagc tgtctttgaa aaggaaggta
    13861 aactgcttga agcccagcgt ttgaaacagc ggacagagta tgatatcgaa atgttgcgtg
    13921 agatgggcta taccaatggg gttgaaaatt attctcgcca catggatgga cggagcgaag
    13981 gagagcctcc ttatacgctt ctcgacttct tcccagatga tttcttgatt atgattgacg
    14041 agagtcatat gaccataggg caaatcaagg gcatgtacaa tggagaccgt tcgcgtaaag
    14101 aaatgctggt taattatggt ttccgtttgc cgtctgcttt ggacaatcgt cctctccgtc
    14161 gggaggagtt tgagagtcac gttcatcaga ttgtttacgt ttcagcgaca cctggtgact
    14221 atgaaaatga acagaccgag acagtgattg agcaaatcat tcgtccaacg ggactcttgg
    14281 atccagaggt ggaagtccgt ccgactatgg gacagattga tgacctcttg ggtgaaatca
    14341 atgcccgcgt tgaaaaaaat gagcgtacct ttatcacaac tttgaccaag aaaatggcag
    14401 aggacttgac cgactacttc aaggaaatgg gtatcaaggt caagtacatg cactcggata
    14461 tcaagacctt ggaacggacg gagattatcc gtgacctgcg cttgggtgtc tttgatgtct
    14521 tggtcggaat taacctgctc cgtgaaggaa ttgacgttcc tgaagtgagc ctcgtagcta
    14581 ttctcgatgc tgacaaggaa ggtttccttc gcaacgaacg tggactcatc cagactattg
    14641 gacgtgctgc tcgtaacagt gaaggccatg tcatcatgta tgcagacacg gttacccagt
    14701 ctatgcaacg tgctatcgat gaaactgccc gccgtcggaa aattcagatg gcctataatg
    14761 aagagcatgg tatcgtacca cagacaatca agaaagaaat ccgtgacctg attgccgtga
    14821 ccaaggcagt tgctaaggaa gaggacaagg aagtcgacat caatagcctc aacaaacaag
    14881 agcgcaaaga actcgtcaag aaactagaaa aacaaatgca agaagccgtc gaagtgcttg
    14941 actttgaact ggcggctcag atccgtgata tgatgttgga agtcaaggcc ttggattagg
    15001 ggaatagtat gatttattta agaaagttaa agagagaaga tttgatgtct ttatgggaaa
    15061 tggcttattc acaacttaat ccagtttgga aacagtatga tgctccctat tatgatgatt
    15121 atcagtattt ttcaaatttt aaagaattcg aactacaaaa atcagaatcc attttaagca
    15181 actcaaatcg ccttggtatt tttgttgatg ataaactagt tgggactgtt tcgcgttatt
    15241 gggtatgtaa acaaacaaga tggatggaat tgggaattgg tatttatgat aaaaaattct
    15301 ggaacactgg tattgggaaa gttgctatgt tgcagtggat agataggacg tttcaggatt
    15361 acttggagtt ggagcatctg ggtttgacaa cttggtcagg gaatcttggt atgatgaaac
    15421 ttgctgaaaa attaagaatg aaaaaagaag ctcatattcc aaaagttcgt tattatcaag
    15481 gtaaatattt tgatagtatt aaatatggta ttttgagaga agactgggag aaaataaatg
    15541 acggttatta tcaaatcaat ggaaactcct aaagagatag aaggtaaatc ccttgttcac
    15601 tggcaaatgt ggagagaggc ttatgatgac cttttgcctg cagaatttca ggagacaatg
    15661 acattagaaa gatgtcgact ctttagtcaa aagtatccag aaaatacatt gattgcgata
    15721 ggtgatctga aggtagttgg ttttatcagt tatggtaact ttcgtgatga gactatgcaa
    15781 gctggtgaaa ttattgcttt atatgtttta aaagactatt acggaaaagg cattgcacaa
    15841 aagttaatga aagcagcttt gactgctctg aatcattttt ctgaaatttt cttatgggta
    15901 ttgaaagata acaagcgagc cattgctttc tatcaaaaaa tgggttttac ttttgatgga
    15961 caagaaaaga tacttgaact tggaaagcct ataaaggaaa aacgaatggt attctattct
    16021 aaaataattt taaaaagtag aagctaatgg cactggtacc aagtctgaaa atttaataaa
    16081 ttagaaagcg agtaaattta tgtcccgttc ccaattaacg attttaacca atatttgtct
    16141 gattgaagac ttagaaactc agcgcgtagt catgcagtat cgctctcctg acaccaatcg
    16201 ctggtcaggt tatgcctttc ctggaggtca tgtagaaaat gatgaggctt ttgcggagtc
    16261 tgtcattcgt gaaatctacg aagaaacagg gttgactatc caaaatcctc aacttgtcgg
    16321 cattaaaaat tggccactag atacaggtgg gcgctacatt gttatttgtt ataaggcgac
    16381 tgagttctct ggtacccttc gctcttcaga agagggagaa gtttcttggg tgcaaaaaga
    16441 ccagattcca aacttggatc tggcctatga tatgctacct ctgatggaga tgatggaagc
    16501 tccggacaaa tcagagtttt tctaccgtca tcgtacagaa gacgattggg aaaagaaaat
    16561 tttctaatcc tttactaaat aaccgagctg ctccaaggcc tcctcgatat agtggaggtc
    16621 ttgttgtgtt tcggcttcga ctaggtggta atggatgcca tctgtcaatt cagatagagg
    16681 tctaaagtca gaatgctcga cttgttctag aaaatgttgc acatctctgc gacaagacag
    16741 tttaagcaag gtttcaattt ctccataaac gggatggtca atcaaggtat tctggacatg
    16801 cccaccatta tcgacaatag caaggagttc ctgaccgatt tcttcaactt catgtttcac
    16861 tttgaaaagt ttgtgaacat aaggattggt atcaatttgc ttatagatgt agccacgatt
    16921 ggtggatagg ataggagcgc catcggctct caaaattgca atgtcctgca caatgacctg
    16981 acgtgtgaca tgaaaatgtt ccgccaaact ttggccatta agggctttag gagcttcttt
    17041 caagagttgg agcagggctt gtttgcgatc ttttgtcata gcttttcctt ttaacggcgt
    17101 tttcgaagca ctttatagac agctagtgct aatgtatagt ctaccatact atggataatt
    17161 gtgccaaatc caactagcac aaatagaaca tagaacatgt tttctacatt ggtacccgaa
    17221 gttgcgtaaa aaaggacaca ggctaatact tcagcaaggg catgaacaac agccaaaaca
    17281 aagttgaaaa cccaggaaga ttttggttta tctagggtat cggggaattt ttgtaggtaa
    17341 agagctccta aagcaccaaa agatatatgg gaaaaagccc gaaaaacgat aaccatggga
    17401 tagccagcca tcaaaaatcc aaaactagag gctaggatga caaaaactgc catcaagggc
    17461 gacaagaaca tggctataaa aatagcgatg tggctcccca aagtatagga agcaggtgga
    17521 atgacaatct tgaaaggcat aacaattgga atcaaaatcg caatagccgt taaaagggct
    17581 gtcattgtca taaattgtgt ctttttccgt gtattcacaa gaatctcctt tttaactgca
    17641 tatacactag tatggtacaa taaaccagac aataaagcaa gaatttactt gggtttatag
    17701 atcatttttt agttaaaagt tatagtagat tgaaactaga atagtccacc tctacttcta
    17761 aaacattgtt agaaatcgat ttggctgtcc tgatcaattt gtcctgttct tatttcgttt
    17821 tactatagta aagatttcat taaaaagaaa ctgtatagag caaaatctcc accttcaggt
    17881 ttgaaagcgg agattgtttt tattttttca aggtttgtag tcgtggaaca atggctaggg
    17941 ttagaattgc agaaatgacc aattcagcaa ttgaatttgt tgagataacg gttgccagaa
    18001 gaagttggat atttccgtta taaacatttc caaataggaa gaagattcct ccaaggacaa
    18061 agatagtatt tgtcaaggaa ccaagagccc cagctaaaat cagaccagtc ttgtttttca
    18121 tcagtttata gactaagtaa ggagttaaac caatcaaaat acgtgggaca atggcaatga
    18181 tagctgagta gatgtttccg tttggtacga agggagagaa gaggtagctt gtcggtagaa
    18241 tcgtaatcgt gttaaccgtc aagctaagta atcccatcaa aaatccaagt gtaaccccaa
    18301 ctcgtggacc ataaataatg ctggcaataa tgacaggaat atgaacaatg gtcggtttga
    18361 ttggaaatgg aaaaaggtta aagataagtg agctcagaaa gtgtatcacg agcatggtag
    18421 caaaaaagat agcaatgggt gcaatattag agcgtttttt catcgatagt ttcctttatt
    18481 ctttctaaaa taattgtgag gtcagctaaa gctcctcgtc cgtggtctcc acaagctagt
    18541 agggattcct taggagcaat cagctgatag ccgtaggttt ctaatgtttt cagattattc
    18601 tgagttactg gatggtcata catttttgta ttcatagcag gagctattag tttgggaata
    18661 tgacttggta gggctagagc tgtactggtt accatgttgt ccgcaaatcc gtgagctagt
    18721 tttgcaatag tgttagcagt tgcaggtacc acgataaata aatctgcttt ttttccaagt
    18781 tcgatatgat tgacctgatc aggatagggt tctttcatga catccaagtg gacaggattc
    18841 tgtgagagta cctgtagtgt caaaggttgg ataaactctg tagcagcctg agtcattaag
    18901 acagtgactt gatggccttg tttttttaga gaactgacta aatctgccga cttataagag
    18961 gcgattgaac ccgttacagc caagagaatg tttgccatag ttttcctttc taagaatgat
    19021 aggcttgaat tttttcaagg aggagttctg caatttcttc tttagtctgg actgtttgaa
    19081 gctgattttt ctcaacaaat atagctcggt gctgatctgc tgaaatttga gtcaggtcat
    19141 tcgcgatgat taaatctgct tgattcttga taagactttt tcgtgcaatg tcaaccagat
    19201 gatcttcggt aacatcaacc agcagtttga aaccaatcag atgaatagta ggattccatt
    19261 ccttgactag ggatatgatt ttgggtgtct ttttaaggaa caaaacctga acctcatcag
    19321 ttgaagaaat cttggcctga tgattctgct tgcttaaaaa ttcttttaga ttggagctag
    19381 cctgaacttc ctcaagccct gtcatataaa caggagtgta gtcagaaaca gccattgagt
    19441 ggatcaagac ctgataatcc tgaacacgtt cttgtatttc tattagaagg tccttggtat
    19501 tggtaatttc tcgaatactt aggttaggat gaggctctgg cttcagagct cgttttgtcg
    19561 taattaaaca aacttcatgc cctgcagaaa gcaaagtctc tgtgataatt ttccccaagt
    19621 gacctgtaga atggttagtg atagagcgga cgctatcgat agcttcactg gtaccgccca
    19681 atgtaactaa aattttcata gcactattgt acacaaaaat aagcggtaag taaaatgaaa
    19741 gtgataaatt tttggtaaaa acgaagattt actatagttt caaactataa agccatataa
    19801 aatttaagaa aggactctaa aagccttaaa aaacagagat atttacgaac gtttagagag
    19861 ttttagggtg ttaaaaatct tgttttgtga tataatgaat tatcatataa gaggttagag
    19921 gaattttgaa tgaaaacaga tattgaaatc gcacagagta ttgagttgaa gccaattgtt
    19981 gatgttgtag agaaacttgg tatttcttac gacgatttgg agttgtacgg aaagtacaag
    20041 gctaaactca gctttgataa aattcgtgca gttgagagca atccagtcgg taaattgatc
    20101 ttggttactg ccatcaaccc aacacctgca ggtgaaggaa agtcgacgct taccattggt
    20161 cttgcggatg ccttgaacaa gattggcaag aaaaccatga ttgctatccg cgaaccgtct
    20221 cttggtccag tcatggggat caagggtggt gctgctggcg gtgggtatgc acaagttctg
    20281 ccaatggaag acatcaacct ccactttact ggagatatgc atgctattac aactgccaac
    20341 aatgcccttt ctgccttgat tgacaaccac ttgcaccaag ggaatgagct gggaattgat
    20401 caacgtcgta tcctctggaa acgcgctgtg gacttgaacg accgtgcgct ccgccatgtg
    20461 actgttggtc ttggtggtcc tctaaacggt attccacgtg aggatggttt tgatattaca
    20521 gttgcttcag aaatcatggc aattctttgc ttggcaacgg acatcgagga cttgaaacgt
    20581 cgtttggcga atatcgttat tggttatcgc tatgaccgta cgcctgtttc tgtaggtgat
    20641 ttgcaggttg agggtgcctt ggctttgatt ttgaaggatg ctattaagcc aaacttggtt
    20701 cagacaattt acggtacacc tgcctttgta cacggtggtc catttgccaa tatcgctcat
    20761 ggatgtaact ctgttttggc gacgacaaca gcccttcact tggctgatta cactgttact
    20821 gaagctggtt ttggtgcgga ccttggtgct gagaaattcc ttgatatcaa gacaccaaac
    20881 ttgccaacat ctccagatgc agttgttatt gtcgcaaccc ttcgtgccct taagatgaat
    20941 ggtggtgtga ctaaagacgc tctgactgaa gaaaatgtag aggcagttcg tgcaggtttt
    21001 gctaacttga aacgccacgt tgaaaatatc cgtaagttcg gtattccagc agttgtagct
    21061 attaacgaat ttgtatctga tacagaagct gaaattgcag tcttaaaaga actctgtgcc
    21121 tcaatcgatg taccagttga attggctagt gtctgggctg atggagcaga aggtggagta
    21181 gcacttgccg aaacagttgt taagacaatt gctgaaaatc cagctaacta taaacgtttg
    21241 tatgataatg acctttctgt ccaagaaaag attgaaaaaa ttgtcactga aatctatcgt
    21301 ggtagcaaag tgaactttga gaagaaagct caaacacaaa ttgctcaaat cgttcaaaac
    21361 ggttgggaca aattgccaat ctgtatggct aaaactcaat acagtttctc agacaatcca
    21421 aatgcgcttg gagcaccaga aaactttgaa attaccattc gtgaattggt accaaaatta
    21481 ggtgcaggct tcatcgttgc cttaactggt gatgttatga ccatgccagg tcttccaaaa
    21541 cgtccagcag ctctcaacat ggatgttgaa agcgatggaa ctgtactagg cttgttctag
    21601 tggattgaaa ttgactttaa gtgagtttgg aaataatatc caagctcatt ttttctcaga
    21661 ctgcaagcag ttcatcaata agatttatac tcttcgaaaa tctcttcaaa ctatgtcagc
    21721 ttcaccttgc cgtaggtata tgatactgac tctgtcagtt ctatccacaa ccttaaaaca
    21781 gtgttttgag caacctgcgg ctagcttcct aatttgctct ttgattttca ttgagtataa
    21841 gtagatagaa aagttatata ctatctattg aaaatattat aaatcagata caaagacagg
    21901 tgaaaccttc tgtgttatac tagagatatg ttagatttga aagaatacgg tatcgtcatg
    21961 tggccggagg agaaagtcat ttctttccgt gagaaacttc tcgcttggta tgatgaaaac
    22021 aaaagagatt tgccttggag gagaagtaaa aatccttatc acatctgggt atctgaaatc
    22081 atgcttcagc agaccagggt ggatacagtt atcccttact acgaaagatt cctggactgg
    22141 tttccaactg tcgaaagtct ggcaactgcg cctgaggaga gtttactgaa agcttgggag
    22201 ggcttgggct attattctcg agttcgcaat atgcaggctg cagcccagca gattatgact
    22261 gactttggtg gccaatttcc aaatacctac gaaggaattt ccagcttgaa agggattgga
    22321 ccttacacag caggagccat ttccagtatt gcttttaact tgcctgagcc agctgtagat
    22381 ggtaatgtca tgcgggtctt ggcgcgtctg tttgaagtca accacgatat tgggattcca
    22441 agtaatcgaa aaatttttca ggcaatgatg gagatcttga ttaatccgga tcgtccgggt
    22501 gattttaatc aagccttgat ggacttaggg tctgatattg agtctcctgt aaatcccaga
    22561 cctgaagaaa gcccagtcaa ggactttagt gcggcatatc agaatggaac catggaccgt
    22621 tatccaatta aatctcctaa gaaaaagccg gttcctattt atcttaaagc cttagttgtg
    22681 aaaaattctc aaggacaatt tttacttgaa aaaaatgaaa gcgaaaagct cttggcaggt
    22741 ttttggcatt tcccctttat agaagttgat aacttttcgc aagaagagca gtttgacctc
    22801 tttcatcagg ttgcggaaga aagtgtgaac tttggtccca gtccagaaga gagtttccag
    22861 caggactatg acctagatgt tgattggctt gatgtttgtt ttgatacagt ccagcatgtt
    22921 tttagtcatc gaaaatggca tgtacagatt gtagcaggtc aggtgagtga cttccatgat
    22981 ttttcagata gggaagttcg ctggctttca ccagaagaat tcaagaatta cccacttgcc
    23041 aaaccccaac aaaaaatctg gcaggcttat gcacaagcca acttagacag tagccaagac
    23101 tagctattgt gtcttctgac tatttttttg gtataatagt agagaaaaag gtgaacatat
    23161 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
    23221 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
    23281 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
    23341 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
    23401 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
    23461 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
    23521 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
    23581 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
    23641 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
    23701 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
    23761 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
    23821 gacacgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
    23881 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
    23941 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
    24001 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
    24061 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
    24121 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
    24181 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
    24241 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
    24301 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
    24361 atggtgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
    24421 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
    24481 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
    24541 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
    24601 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
    24661 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
    24721 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
    24781 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
    24841 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
    24901 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
    24961 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
    25021 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
    25081 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
    25141 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
    25201 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
    25261 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
    25321 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
    25381 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
    25441 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
    25501 aaggtgaatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
    25561 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
    25621 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
    25681 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
    25741 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
    25801 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
    25861 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
    25921 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
    25981 tcaccagata ccgcaacacc attgacagag atataaaaag aacgctgaga aggtgttctt
    26041 tttatattga ctgaacacat aaaaagtaat acaatggtgt taccattaaa aaagggagca
    26101 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
    26161 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
    26221 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
    26281 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
    26341 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
    26401 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
    26461 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
    26521 taattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
    26581 tggtcatcgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
    26641 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgataca acaattattt
    26701 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
    26761 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
    26821 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
    26881 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
    26941 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
    27001 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
    27061 tatatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
    27121 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
    27181 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
    27241 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
    27301 atgaacagat aaaacttgat aaactcaaag acgaattatc gagccaaaga atattaatag
    27361 agaaacaatc tgaaaaaatc gaagaactac atcgaatgat aaaagactta gttgaaaaaa
    27421 tatcataaag gtgagacaaa acaaaacttg attcgaggag aaatcaagta agttttgaca
    27481 caatagaacg catattatca ggtataaaaa tttgataata tgcgttttat agagaaatga
    27541 aataaaattt gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
    27601 atggggtgct atttcaactt caacctacta taatacagaa agaaacaact ccctgatgat
    27661 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tggatttttc
    27721 catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
    27781 gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac aacagctggt
    27841 tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga aagtggaagt
    27901 actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
    27961 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
    28021 aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc ttcaaggttt
    28081 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
    28141 atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc ttgacggaaa
    28201 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
    28261 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
    28321 aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
    28381 aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac aacaaggtca
    28441 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
    28501 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
    28561 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
    28621 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
    28681 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
    28741 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
    28801 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
    28861 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
    28921 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
    28981 aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac cccagacaaa
    29041 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
    29101 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
    29161 cttgtagatg gtcatgggaa ttttggttct atggatggag atagtgctgc cgctcaacgt
    29221 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
    29281 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
    29341 cgttttccaa accttttggt taatggagca actggtattg cggttgggat ggcaaccaat
    29401 attccacctc ataatctggg tgaaaccatt gatgtagtga agttggtcat ggataatcct
    29461 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
    29521 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
    29581 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
    29641 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
    29701 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
    29761 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
    29821 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
    29881 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
    29941 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
    30001 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
    30061 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
    30121 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
    30181 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
    30241 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataaa
    30301 cgccgtacag agttgatggt tggacagttc ttgagtctcg aggatgagga cttgattgaa
    30361 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
    30421 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
    30481 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
    30541 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
    30601 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
    30661 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
    30721 gtgaagagaa ccagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
    30781 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
    30841 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
    30901 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
    30961 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
    31021 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
    31081 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
    31141 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
    31201 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
    31261 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa tgaaacagaa
    31321 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
    31381 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
    31441 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
    31501 agaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
    31561 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
    31621 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
    31681 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
    31741 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
    31801 tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa gtttatactt
    31861 atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt gatgatagag
    31921 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
    31981 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
    32041 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
    32101 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggacgaatc
    32161 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
    32221 tttcaatcta ctataaactt ttatgaaata tagaaaacgc ttcctaaaac ctaaagtttg
    32281 tgatataatt atcaagaaaa aagatttagg agtttattat ggtttcttca gaatttatct
    32341 caaagattga atttgcttgc aataagaaag aaagtcttta tagtcaaagc aaatttaagt
    32401 atgcgattcg ttcgatgttc gcaggtgcat ttttaacctt cagtactgct gcaggtgcag
    32461 ttggggctga cttgattaat aaaattgcac caggtagtgg acgcttcctc tttccattcg
    32521 tttttgcttg gggcttggcc tacattgttt ttttgaatgc cgagttggtc acttcaaaca
    32581 tgatgttctt gactgctggt agtttcttaa aaaaaatctc ttggagaaaa acagctgaga
    32641 ttttactata ctgtaccttg ttcaacctta tcggagcctt gatagcaggg tggggctttg
    32701 ctcattcggc agcctatgcg aatctgacac acgatagttt catctcaggt gttgttggga
    32761 tgaagttagg ccgctcaaat gaattggtct tgcttgaggc gattttggca aatattttcg
    32821 taaatattgc gattctgtca tttattttgg tcaaagatgg tggtgccaaa ctttggcttg
    32881 tgttgtcagc tatttacatg tttgtattct taacaaacga gcacattgcg gcgaactttg
    32941 cttctttcgc gattgtgaaa ttcagtgttg ctgcggattc aattgccaac ttcggtgttg
    33001 gaaatatgct tcgccactgg ggtgtgactt tcatcggaaa ctttatcgga ggaggcctct
    33061 tgatgggtct tccatatgcc ttcctcaata aaaacgaaga tacttatgta gattaagaaa
    33121 atgagcacga ttgagtcgtg cttttttcat tttcaaaata aggtaatagc tatttcttat
    33181 atcaaaatat agaaaactga tatttgtaaa ctataactca aggtgctaca atatccttaa
    33241 taaaataata tggaggtcac cttatgactc gtgattttaa atttgaaact ctacaactac
    33301 atgctggtca agttgtggct ccagctacta agtctcgtgc agtgccgatt tatcaaacaa
    33361 cattttttgt ttttgatgac acgtaggaag gtgccgatct gtttgccttg aggaaatcag
    33421 ggaacattta tactcgtatc accaatccta caacagctgc ccttgaaggt ggtgttgaag
    33481 cgctagcaac agcatcaggt atgactgcag tgacttatac gattttggcg cttgcccatg
    33541 ctggtgagca tgtagtggct gcttcgacta tttacggtgg aaccttcaat cttttgaaag
    33601 aaccccttcc tcgttatggt atcacaacaa cctttgtcga tgttgataat ttggaggaag
    33661 tagaagcagc tatcaaagac aataccaagc ttgtcttgat tgaaaccttg ggtaacccct
    33721 tgattaatat tccagacctg gaaaaactgg cagagattgc tcataaacat caaatcccac
    33781 ttgtgtcaga caatactttt gcaacacctt atttgattaa cgtcttctct catggcgttg
    33841 acattgccat tcactctgcg actaagttta tcggtgggca tggtacaact attggaggaa
    33901 taattgtcga tagtggtcgt tttgactgga cggcttcagg gaaattccct caatttgttg
    33961 acgagagtcc aagctgccac aatttgagct atactcatga tgtgggtgca gcagccttta
    34021 ttatagctgt tcgagttcaa ttgcttcgtg atacaggtgc agccttgtca ccattcaatg
    34081 ctttcctctt gctacaaaga cttgaaaccc tttcacttcg tgtggaacgc catgtacaaa
    34141 atgctgagac aattgttgat tttcttgtca accatcctaa ggtagaaaag gtaaattatc
    34201 caaaacttgc agatagtcct tattatgcct tggctgagaa atacttgcca aaaggtgtcg
    34261 gttcaatctt taccttccac gtcaaaggtg acgaggagga agcacgcaag gtcattgata
    34321 atttagaaat cttttctgac cttgcaaacg cggcagatgc taaatcgctt gttgtccatc
    34381 cagcaacaat cactcacggt caattgtcag aaaaagacct agaagcagca ggtgtcacac
    34441 caaatcaaat ccacttgtct atcggtcttg aaaatgtaga agatttgatt gaagacttac
    34501 gcttggcctt ggaaaaaatt taaagtaaaa gaagataaac agtgggtttt gactcactgt
    34561 ttttgatttt ccctcaggca tgatataatg gttacagaag tctagaaaga ggaatgtaat
    34621 gaacgaaatc aaatgtccca actgtgggga agtctttaca gtaaatgaaa gccagtatgc
    34681 tgaacttttg tcccaagtga gaacggcaga gtttgataag gaactacacg ataggatgag
    34741 gcaggaactg gccttggctg agcaaaaggc tatgaatgag caacagacta aactggctca
    34801 gaaggatcaa gaaattgcgc aattgcagag tcaaatccaa aactttgata cagaaaaaga
    34861 attggccaag aaagaagttg aacagacaag ccatcaggcc ttattggcta aggacaagga
    34921 agtacaggcc ttggaaaacc agttggcgac cttgcgtttg gagcatgaaa atcaattgca
    34981 aaagaccctt tctgacctag aaaaagaacg caatcaggtc aaaaatcagc tcctactgca
    35041 agaaaaggaa aatgagttgt ctttggcttc tgttaagcaa aactacgaag cccagctcaa
    35101 agcagccagt gaacaagtcg agttttataa gaattttaag gctcaacaat ctacaaaagc
    35161 gattggggaa agcctagaac agtatgcaga gagtgagttt aacaaggttc gtagtttcgc
    35221 ctttccaaat gcttactttg agaaggataa caaggtctct tcgcgtgggt ctaaagggga
    35281 ctttatcttc cgtgagtgtg atgaaaatgg agttgaaatc atttctatca tgtttgagat
    35341 gaaaaacgaa gcggacggaa cagagaagaa gcacaagaat gcagattttt acaaggaatt
    35401 ggacaaggac cgtcgggaga agaactgtga gtatgccgtt ttggtgacca tgcttgaggc
    35461 tgataatgac tactttaaca cagggattgt tgacgtcagt cacgagtatg aaaaaatgta
    35521 tgttgttcgt cctcaattct ttatccaatt gattggtctc ttacgtaatg cggcgctaaa
    35581 ttccctaaaa tacaagcagg agttggcctt ggttcgcgag caaaatattg acattacgca
    35641 ttttgaggaa gacttggatg cctttaagct agcttttgct aagaactata attcagcttc
    35701 gactaacttt ggaaaagcta ttgatgaaat cgacaaggcc atcaaacgca tggaagaggt
    35761 taagaaattc ctgactacat ctgaaaacca actccgtcta gctaacaaca aattggaaga
    35821 tgtctctgtt aaaaaattga cccggaaaaa tccaaccatg aaagcgaaat ttgaagcatt
    35881 gaagggggag tagaaagcaa aaatgaacgg tattatcaac ttaaaaaaag aagcaggaat
    35941 gacctcgcat gatgcggttt ttaaactgcg taagattttg ggcaccaaga aaattggtca
    36001 tggtgggacc ttggatccag atgtagtggg tgttttgccc attgcgattg gcaaggcgac
    36061 ccgcatggtt gagtttatgc aggacgaggg taaaatctat gagggggaaa tcactctggg
    36121 ctattccacg acgactgagg atgctagtgg ggaagtggtc gcagaaaccc ctgttttgtc
    36181 tcccttggat gaaaagcttg ttgatgaagc gattgcgagc ttgactgggc ctattaccca
    36241 gattccccct atgtattcgg cagttaaggt taatggtcgc aagctctatg agtatgcgcg
    36301 tgctggtcag gaagtggagc gtccagaacg tcaggtgacc atttatcaat ttgagcgaac
    36361 aagtccgatt tcttatgatg gccaacttgc ccgattcact tttcgtgtaa aatgcagtaa
    36421 agggacttac atccgtactt tgtcagttga tttgggtgaa aagcttggtt atgcggctca
    36481 tatgtctcag ttaactcgta ctagtgctgc tggcttacaa ttagaagacg cactgacctt
    36541 ggaggaaatt gctgaaaaag tagaggctgg gcaattagat tttctccatc ctttagagat
    36601 tgggacaggt gatcttgtca aagttttcct aagtccagaa gaagctacag aagttcgctt
    36661 tggtcgtttt attgagctag accaaacgga caaagaactg gctgcctttg aagatgataa
    36721 attgttagcc attctagaaa aacgaggcaa tctctataag ccaaggaagg tttttagcta
    36781 gattgtttag gaataaaaat cgggtgatag ataacaattg cttgataaaa ccccatacta
    36841 atagtagaat agttttggga attataatat tccaattgtt gcgagttgta gatactcaaa
    36901 taatctatat agaaatttag aggtgtgaaa tgaagcaact taaaattctt tcagataaat
    36961 atttagagtc cattacaggt tctggtggga acttaggccc aggatttggt gtgataattc
    37021 catgatgcga aatgagtttc gagaaagggt ggagcaactt cttcaacaaa aagaaataaa
    37081 tgaaaatagt gagttgagtc acctgtttcg tcttgctata caaaatttag acagaaatga
    37141 aaaataccaa tcggtcatgg ccaatttgag tcaagggttg tcactttacc tcatgacgca
    37201 tcattaccag gcacctaagt ctgtcattga ttttggttta tggattgcca aagctcctag
    37261 ccaggaaaga gggagactgg ctttcttgca gatgcttgct caaaccctac agggctttcg
    37321 ttaaaactgt cgaacatcag agggaagact ctggtgtttt ttgctgatga gactataaat
    37381 tttgtaaaaa atgtgataga atagacgacg gataaaataa cggaggatag catgcaaaat
    37441 agaccaatca ttattggagt gacaggtggt tctggtggtg gtaaaaccag tgtttcaaga
    37501 gccattttat cgcattttcc tgatgaaaag atttccatga ttgagcatga ttcatactac
    37561 aaggatcagt ctcatttgac ctttgaagag cgtgtcaaaa ccaactatga ccatcctttt
    37621 gcctttgata cagacttgat gatcgagcag attaaggaat tgttggcagg gcgtccggtg
    37681 gacatcccga cctacgacta tacagagcat acacggagta gcaagaccta tcgtcaggag
    37741 cctcaagatg tctttatcgt tgagggcatt ttggtcttgg aggacaagcg tctgcgcgat
    37801 ttgatggata tcaagatttt tgtggatacg gatgacgatg tgcgcattat tcgtcgtatc
    37861 aagcgtgata tggaggagcg tggccgtagc cttgatagcg ttattaacca gtacttaggt
    37921 gtggtcaaac caatgtacca ccagtttatc gagtcaacta agcgttatgc tgatatcgtc
    37981 attcctgaag gggttagcaa taccgtggct atcgacctgt tgacgaccaa gattgcaaag
    38041 attttggaag aagctcgaaa cagcaaataa tcacatgtgg aggccttgcc tcctttttct
    38101 atttttccct cataatggta cataaatgga gatttttagg catatttttg gtataataat
    38161 acccatgaaa gagcaagtaa atgaatagta ggtggagatg gaaaagtatt tatcggtaac
    38221 aactttgacc aagtatctga aaatgaaatt cgataaagac ccatacttgg aacgggtcta
    38281 tttaactggt caagtttcca actttcgtaa acgacctact caccaatatt tctccctaaa
    38341 ggatgaccat gcagttattc aagcgaccat ctggtctggg atttatcaga aattagggtt
    38401 tgacctggaa gaaggaatga agatcaatgt gattgggcgt gtacaggtct atgaaccaag
    38461 tggtagctac tccatcatca ttgaaaaagc tgagcctgat ggggttgggg cgcttgcgat
    38521 tcagtttgaa caacttaaga aaaaattgac agaagaaggc ctgtttcaag aacgcttcaa
    38581 gcaagctcta ccccaatttt ctaagagaat tggggtagta accagccgta gtggagccgt
    38641 tattcgagat attatcacga ccgtcagcag gcgattccca ggtgttgaca tccttcttta
    38701 tccgaccaag gttcaaggtg aaggggctgc ggaggaaatt gcaagaaata ttgcgcgtgc
    38761 taatcaacgg gacgatttgg atttgctcat tattggtcgt ggaggtggtt ctattgagga
    38821 tctctgggcc tttaacgaag aaattgtggt acgagctatt tttgaatctc gtttgccagt
    38881 tatctctagt gtggggcatg agacggatgt gaccttggca gattttgtgg cagatcgacg
    38941 cgctgcaacg ccaacagcgg cggctgaact ggcaacacct gtgaccaagt tggatgtatt
    39001 aactcatttg caaaatcagg aaaaacggat ggcaacggca gtccgaaatg ttctatctaa
    39061 gaaacaagag gctttgaaaa aatgcagtca gtctgttatc tttagacaac ctgagcgctt
    39121 gtatgacggt tatttgcaac gcttggacca actgcaactg cgtttgaaac aaagtttgcg
    39181 aactcggatt tctgataaca aacaattagt tcaagcaaga actcatcaat tagtacaatt
    39241 atcacctgtt accaaaatcc aacgctatca agaccgttta ggacagttgg acaagctctt
    39301 aggtagccaa atggcgttag tttatgacgc caaggttgct gaggccaagc gactttcgga
    39361 agctttgctc atgttggata ctagccgaat cgtggcgcgt ggttatgcta ttgtcaaaaa
    39421 agaagagtcc gttgtagatt cggttgagag tttgaagaaa aaagaccaag taacgctttt
    39481 gatgcgagat ggtcaagtag aattagaggt taaagatgtc aaaacaaaag aaatttgagg
    39541 aaaatctagc agaactggaa accattgtcc aaagtttgga aaatggtgaa attgctctgg
    39601 aagatgcgat tactgccttt caaaagggca tggtcttgtc aaaagagctc caagctacgc
    39661 tggacaaggc tgaaaagacc ttggtcaagg tcatgcaaga agacggaaca gaaagtgatt
    39721 ttgaatgaaa aagcaagaaa aattagctct tgtcgagtcg gctttggaag atttttatgg
    39781 agaccagcag tttgcctcta gtttacggga gtctgttctc tattctattc atgctggtgg
    39841 caagcgtatt cggccttttc tcttgttaga agttctggaa gccttgcagg ttaccatcaa
    39901 acctgctcac gcgcaggtag ctactgcctt ggagatgatt catacaggga gcttgattca
    39961 cgatgacctt cctgctatgg atgatgacga ttatcgaaga gggcggttaa ccaatcacaa
    40021 gaaattcggt gaagctatgg ccattttggc tggagatgcc ttattcttag acccatatgc
    40081 cttgattgcg caggcagatt tgccaagtca gatcaaggtg gacttgattg ccaacttatc
    40141 ccttgcttca ggtagtctgg gtatggtggc agggcaagtt ttggatatgg agggcgaaca
    40201 ccagcacttg tctctggaag aacttcagac tattcatgcc aataagactg ggaagttact
    40261 agcctatcct ttccaagcgg cagctattat agctgaattg tcacctgaaa tgcaggtgaa
    40321 gctgaaaact gtgggtgaat tgattggact tgcttttcaa gtcagagatg atgtactgga
    40381 tgtgacagct agttttgagg aaatcggcaa gacacctcaa aaggatctgc aggcagaaaa
    40441 atcaacctat cctgccttgt tgggcttgga agagtccatt gccttttgta accaaaccct
    40501 ggatcaagct aatgaaaaat tagaagaaat tgcccagcag cttccctttg aaacagaatc
    40561 gattgtaagt gtagtagaaa gtttgagaat caatggctaa ggaaagagtg gatgtactag
    40621 cttataaaca ggggttgttt gaaacgagag agcaggccaa gcgaggtgtg atggctggcc
    40681 tagtcgtagc agtccttaat ggagaacggt ttgacaagcc aggagagaaa attccagatg
    40741 acaccgaatt aaaactcaag ggggagaaac tcaagtatgt cagccgtggt ggtttgaaac
    40801 tggaaaaggc cttgcaggtc tttgatttgt cggtggatgg cgcgactacg attgatatcg
    40861 gggcctctac tggaggtttt accgatgtca tgatacagaa tagtgccaag ttggtctttg
    40921 cagtcgatgt tggtaccaat cagttggctt ggaaattacg ccaagaccca cgagttgtca
    40981 gcatggagca gttcaatttt cgctatgctg aaaagactga tttcgagcag gagccgagct
    41041 ttgccagtat tgatgtgagt ttcatttccc ttagtctgat tttgccagcc ttgcaccgtg
    41101 tcttggctga tcaaggtcag gtggtagcac ttgtcaaacc tcagtttgag gcaggacgtg
    41161 agcagattgg gaaaaatgga attattcgag atgctaaggt tcatcagaat gtccttgaat
    41221 ctgtaacagc tatggcagta gaggcaggtt tttcagtcct tggcttggac ttttctccca
    41281 tccaaggtgg acatggaaat attgaatttt tagcgtattt gaaaaaagaa aagtcagcaa
    41341 gcaatcagat tcttgctgag attaaagaag cagtagagag ggcgcatagt caatttaaaa
    41401 atgaataaaa aagaaagact tgaaaaaatt agaagattgg tgacagatta tcaaatcggc
    41461 acgcaagaag aaattgtaga acatttgaaa gaagcaggta tcactgccac tcaggcgacg
    41521 gtatcccgag atatcaaaga gttaggtatt gtcaaaattc ctttgagaga caacacctat
    41581 gtctacgaat taccaaaatc aatcgtaaaa agtctgcaac tggctgaaga caatatcgaa
    41641 tcggctgaat tgatggataa gatgatcaat ctccaagtta ttccaggaaa tacggctttt
    41701 gtaaaagctc agttaatcga gacttttgca gacaagattt ttagctgttt gactgatgat
    41761 agctcgattt tagtcattgc cagaagtgga agtctagcag aggaaatctt tgaacaagta
    41821 aaaaattggt aggtctatat gttacttgaa atttcgataa aaaactttgc cattattgaa
    41881 gctatttccc tcaattttga aaaggggatg actgtcctga ctggtgaaac gggtgcaggg
    41941 aagtcgatta tcattgatgc catgaatatg atgttgggag ctcgtgcgac gacagatgtt
    42001 attcgtcatg gtgcaccaaa ggcagagatt gaggggcttt tctcagttga gaatagtcgt
    42061 cttttacagg aaatttttga tgagcaaggt ttagaattag gtgatgaaat tatcatccgt
    42121 cgggaaatct tgcaaaatgg tcgtagtatc agccgtgtaa atggtcagat ggttaatctg
    42181 tctgttttgc gagctattgg gcaacatctt gtagatattc atggtcagca tgaccatgag
    42241 gagttaatgc gtccccaact gcatatccag atgttggatg aatttggtga tgccgctttt
    42301 tgggacttga aagaaaccta tcaaacgagt tttgatgcct atcggaaaat gcgcaagcag
    42361 gttctggaag tcaagaaaaa ccaacaggaa cacaaggaac gtatcgaaat gttggaattt
    42421 caaatggcag agattgaggc agcaaacttg caggctggag aagacttggc tctcaaccaa
    42481 gagcgagata aactcctcaa ccacaaaaat attgcggata cactgaccaa tgcctacagt
    42541 atgttggaca atgaagattt ttcaagtctg gccaatgttc gttcagctat gaatgacatg
    42601 gaaagtgtcg aagagtatga tcctgaatac cgtgaaattt caagctctct gtctgagacc
    42661 tactatgttt tagaagacat tagcaaacgt ttggaagcta tcattgagga ccttgatttt
    42721 gatggcaatc gcctcatgca ggttgagaat cgtttggacc tccttcatac tattactcgt
    42781 aagtatggtg gaactgttga tgatgttttg ctttattttg ccaagattac ggaagaatac
    42841 aatctcttga caggcaataa tctttcgtct gaggacatgg aagcagagct taagaagttg
    42901 gaagtcaatc ttgtcaattt ggcaggtcaa cttgcttctg ctcgtcataa tttagctcag
    42961 caactcgaag ctgagattaa acaagaactg caagatcttt atatggaaaa agcccagttt
    43021 caggttcgtt ttagtaaggg aaaattcagt cgtgagggaa atgaaatggt tgagttttat
    43081 atttcaacca accctggaga agactttaaa cccttggtta aggttgcttc tggaggggaa
    43141 ttatctcgtc tcatgttagc cattaagtct gccttttcac gtaaagaagg caagactagc
    43201 attgtctttg atgaggtgga tacgggagtt tcaggtcgtg ttgctcaagc tattgctcag
    43261 aaaattaata aaattggtca gcatggtcag gttttggcta tctcccattt gccacaagta
    43321 attgcgattg cagattatca attctttatt gagaagatta gtaatgacca ttcaacggtt
    43381 tcgactgttc gtcttttgac ggtcgaagag cgagtggagg aagttgccaa gatgttggca
    43441 ggtgataatg tgacagaagc agccctgacg caagccagag aattgttgag aaacagggag
    43501 aaataagatg acagattatt atgtaattgg agatgttcac ggaaaagctg ggatgctgga
    43561 agaccttctc aaaacctggg atggtcagcc ccagttgctc tttctaggtg atttgattga
    43621 cagaggtgag gatagtcacc gtgttcttga aatggtcaag gacttggtgg acaatcaagg
    43681 ggctatctgt ttgtccggaa accacgagta tatgtttttg acttggctag atgacccaga
    43741 agaaagttat gaccattatc gtcgcaatgg tggagataca accattaact ctatcctagg
    43801 tcgtcccttg gatgcaccag ttgatggagt agaagatgcc aaacgggttg ccgctgaagc
    43861 ggcagacttg gtcgaattca ttcgtcaaat gccatttgta gtagagacag acaagtatat
    43921 ctttgttcac gcaggtattg atttgacctt ggatgattgg catgaaacaa cagattataa
    43981 aaaagtctgg ctcagaaaac cgttccacga agccgaaaat catactggaa aaactattgt
    44041 cttcggtcat acaccggtct atggtttgtt acagcaagaa cgcggtacat ctgagctttg
    44101 gactacagaa gatagcaaga ttggcatgga cggaggagct gtctatggtg gggtccttca
    44161 cgggattgtc tttactgacc agggaatgac agaacactac tttatcgaaa atgacggctt
    44221 tgttgctgaa gattagtact cctagcaggg tatggtcttg tcaaaatgtc aaaaacaatt
    44281 tataataaat agataccctg aaaggaagag aatcatgaac ttagaagaat tgaaaaaacg
    44341 acaggagaag atccgtaact tctctattat cgcccatatt gaccacggga aatcaactct
    44401 agcagaccgc attttggaaa aaacagagac ggtttcaagt cgtgaaatgc aggcccagct
    44461 tttggatagc atggatttag aacgggaacg tgggattacc attaagttga atgccatcga
    44521 gctgaattac acggcaaaag atggcgatac ttatatcttc cacttgattg acactccggg
    44581 gcacgttgac tttacctatg aagtttcacg ttcgctcgct gcctgtgagg gggctatttt
    44641 ggtggtcgat gctgcccaag gaattgaagc tcaaaccctt gctaacgttt atctggcctt
    44701 ggacaatgat ttggaaatca tgcctgtcat taataaaatt gacctgcctg ctgcagatcc
    44761 agagcgcgtg cgtacggaga ttgaggatgt gattggtttg gatgccagtg aagcagtttt
    44821 agcatctgcc aaggctggca tcggtatcga agagatccta gagcaaattg tagaaaaagt
    44881 accagaacca acgggtgatg tgacagcgcc tcttaaagcc ttgattttcg actctgttta
    44941 cgatgcttac cgtggggtta ttctccaagt tcgtgttatg gatggggtgg ttaaacctgg
    45001 ggataagatt cagctcatga gtaatggcaa gacctttgat gtgacagaag ttggtatttt
    45061 tactccgaaa gcagttgatc gtgatttcct tgcgacgggt gatgttggtt atattgcggc
    45121 ttctatcaag acggttcagg acacccgtgt cggtgatacc gttactttgg caaccaatcc
    45181 tgcggcagag tccttacatg gttacaagca gatgaatcct atggtctttg cgggtctcta
    45241 cccaatcgag tcaaacaagt acaatgacct gcgtgaagcg cttgaaaaat tgcaactgaa
    45301 tgatgctagt cttcagtttg aaccagaaac atctcaggcc cttggatttg gtttccgttg
    45361 tggattcctt ggacttctcc atatggatgt tatccaagaa cgtttagaac gtgagttcaa
    45421 catcgacctc atcatgacag ctccatccgt tatctataag gttaatcaaa ccgacggtga
    45481 gtcaatggat gtgtctaacc catctgagtt tccagaccca actaagattg cgaccattga
    45541 agagccttat gttaaagctc aaataatggt accgcaagag tttgttggag cagtgatgga
    45601 attggctcag cgtaagcgtg gggattttgt gactatggat tatattgatg ataaccgtgt
    45661 caatgttatc tatcaaattc cgcttgctga aattgtcttt gacttctttg ataaacttaa
    45721 gtcttcgaca cgtggttatg caagctttga ctacgaattg tcagaatatc gcccatctaa
    45781 gctggtcaaa atggacatcc ttctcaatgg agacaaggtg gatgccctca gctttatcgt
    45841 tcacaaggac tttgcctacg aacgtgggaa actcatcgtt gataagctca agaaaattat
    45901 ccctcgccaa caatttgagg ttccaattca agcagctatt ggacacaaga ttgtggctcg
    45961 tactgatatc aaggcccttc gtaagaacgt acttgctaaa tgttatggtg gtgacgtttc
    46021 tcgtaagcgt aaactgcttg aaaaacaaaa agctggtaag aaacgcatga aagctatcgg
    46081 atcagtagaa gttccacaag aagccttcct tagcgtcttg agcatggacg aagaataagt
    46141 tattataatt gttttcttgt tcacaggaaa tttacataag aatcaatagt aaaacaggct
    46201 taaattggcc tgttttttta gtttttatac tcttcgaaaa tctattcaaa ccacgtcagc
    46261 gtcgccttgc cgtagatatg atcactgact tcgtcagtct tatctacaac ctcaaaactg
    46321 tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
    46381 aacagaaaaa atgctggtag tatttgtttg tgtgtttatt tttatataac aaactacaaa
    46441 cgaaacaaaa atataaaaaa agagacaaaa atcaacagaa aactattgac aacggtttca
    46501 tatagtgtta tacttatggc ataaagttaa tggaaagaag ggaaaacttt atgggattag
    46561 atcatttctt tgacaaaaac cttgtgtttt gcttagaagc ggataatcaa gaacatctct
    46621 ttgatcaggt tgcaacttta ttggaagaac gagaaattgt aactccaact tatcgtgaag
    46681 ccttgatcac gcgtgaaaag tcatttccaa ctggcttaga tatggaattt ttgggtaagg
    46741 atttgccgaa tgtggctatt cctcatacag atattgttta taatctagct gaaaaagttg
    46801 tggtcgttcg attagagaaa ccggtgactt tccacaatat gattgcgcca gataaggaag
    46861 tagaagtatc cttgctcttc tttatcatca ataactcaag ttcaagtcaa accaacattc
    46921 ttgctcagtt gatggacttc tttactggaa atggtcatct tgaagaccta tcaaaaattt
    46981 ctgaaccaga acccctctat gcttatatag ctgaagcaat cgcttaatct tgtttattaa
    47041 aaatattaaa tcggaggaaa tccatatgat taaaattctt gctgcctgcg gtgcaggtgt
    47101 taactcaagt caccaaatta aaagtgctct tgaagaagaa ctttcaaacc gtggttttga
    47161 tgttcactgt gatgcggtaa tggtcaaaga cgttaatgaa gatcttatca aaggttatga
    47221 catcttcaca ccaattgctg cgacagacct tggttttgac ccaggtattc cagttatcga
    47281 agctggacta atcttattcc gtatcccagc aatgagtgct ccagtatttg acaatattga
    47341 agcagctatc aaagaacacg ggttaagcta attttaattt gttaacattc atataacata
    47401 aaaaagggag gaactgttat gtatgcaatc tttgacctaa tcggaaaggt tttcaatccc
    47461 atcttagata tgggtgggcc tgtcatcatg ttaatcattt tgacagtatt ggctttactt
    47521 tttggagtga aattctccaa agcgcttgaa ggtggtatca aacttgccat cgctcttaca
    47581 ggtatcggtg ccatcatcgg tatgcttaac actgctttct cagcgtcgct tgcaaaattc
    47641 gttgaaaaca ctggtatcca attgagtatc actgacgttg gttgggcacc acttgctaca
    47701 atcacttggg gttctgcttg gacactatac ttcttgctca tcatgttgat tgtcaacata
    47761 gtgatgctag ctatgaagaa aacagataca cttgacgttg atatcttcga tatctgacac
    47821 ttgtctatca caggtctttt gattaaatgg tatgcagata acaacggtgt gagtcaaggg
    47881 gtttcactct ttattgctac agcagctatc gtccttgttg gtgtgttgaa aattatcaac
    47941 tctgacttga tgaaacctac atttgatgac cttcttaacg ctccaagttc atcaccaatg
    48001 acatcaactc acatgaacta catgatgaac ccagttatca tggttttgga taagattttt
    48061 gaaaaattct tcccaggtct tgataaatac gactttgacg ctgcaaaatt gaacaagaaa
    48121 atcggtttct gggattctaa attctttatc ggtttcatcc ttggtatcgt tatcggtatt
    48181 atgggaactc cacatccaat tgcaggagtt gaagatgcag ataaatggcg tcttgttatc
    48241 agaggatggt tgtctcttgg tttgactgcc ggtgtatctt tggaactctt ctcacttatc
    48301 ggttcatggt tcattgcagc cgtagaacct ctttcacaag gtattacaaa cgttgctact
    48361 aaacgtcttc aaggacgtaa attcaacatc ggtcttgact ggcctttcat cgctggtcgt
    48421 gctgaaatct gggcttgtgc caacgtactt gctccaatca tgttgattga agctgttctt
    48481 ctttcaaaag tcggaaatgg tatcttgcca cttgcaggta tcatcgctat gggtgttact
    48541 ccagctctct tagttgtaac tcgtggtaaa ttgctccgta tgattatctt cggaacactc
    48601 ttgttgccac tcttccttct ttcaggtaca cttattgcac catttgcaac agaacttgct
    48661 aaaggtgtag gtgccttccc agcaggtgtg agccaaactc aattgatcac tcactcaact
    48721 cttgaaggac caatcgaaaa acttcttggt tggacaattg gtaacactac aactggtgat
    48781 atcaaagcaa tccttggtgc tgtagtcttc cttgtattct atatcggtat ctttgcttgg
    48841 tacagaaaac aaatgatcaa acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct
    48901 cctataaaat gtaagctcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
    48961 ctcaaaacac agttttgagg ttgtagataa gactgacgaa gtcagtgacc atatctacgt
    49021 caaggcgacg ctgacgaagt ttgaattgga ttttcgcaga gtgtaaattg ttgaaactag
    49081 gttgtcatac cattaggagt gacagcctag ttttttataa actatcaaga aattggagaa
    49141 aataatggta attgaattaa aatcagaaca attaagtgtt caatttaaca gttttggtgg
    49201 ggctctttct tctataaagg atgctgaggg actggagtat ttgtggcaag gggatgctac
    49261 ttattggagt ggacaagctc ctgttctctt tccaatttgt ggttcattga gagaggatac
    49321 agccctctat atagatgaga aggggcaaga aagtaaagga aagattcctc gtcatggtct
    49381 ggttcgtaag aaagaatttg aattagttga acagacagac aagagtgtaa cttttgcaat
    49441 tgaagacgat gagaatagct atcaaaacta tccttatcat ttccgcctag aaatcactta
    49501 tagccttact ggaaagacag tacggactca atacaaaata tttaataaag aaactagcaa
    49561 ggtcatgcct tactttattg gtggacatcc aggatttaat tgtcctctac tggatgatga
    49621 ggtctatgaa gattactatt tagagtttga gaaagaagag acttgctctg ttccacgtcc
    49681 tttcccagaa acggggatgc tggattttca agatagaagt ccatggctag agggacaaaa
    49741 agaaatagat cttagttatg atcttttcag cacagatgca gtgactttgg atgaattgca
    49801 atctcgaaca attgcccttc gttctcgtaa acatgataag ggggtgaaag tgcactttgc
    49861 agagtttcca aacctcatca tctggtcaac tttgaataag ggacctttca ttgcctttga
    49921 accatggtct ggcttgtcaa catcccttga agaaggagat catttagaag ataagaagaa
    49981 tgttcgtctc ttagaagcca atcaggttga agaaataggg tttgagatag aagttttata
    50041 aaaaagtaaa aaataaataa caaaaaacaa acacaaactg ttgacttttt caaacaatag
    50101 tagtatatta tgtttgtgag gactaattga ctgtttttta aagacagcca atacactgct
    50161 ggaatccagc atagaaaaaa taaaaaggag tatacaatat gtctattgtt atcggtgcag
    50221 atgctgcagg tttgagattg aaagaagttg tgaaagattt cttagaaaaa gaaaatttcc
    50281 accttgtgga tgttacagct gaaggtcgag actttgttga tgtgactctc gctgttgctg
    50341 cagaagtaaa caaagaagaa caaaaccttg gtatcgtgat tgatgcttat ggagctggtc
    50401 catttatggt tgcaacaaaa atcaaaggaa tggttgctgc agaagtatct gacgaacgtt
    50461 cagcttatat gactcgtggc cacaacaact ctcgtatgat cactatgggt gcacaacttg
    50521 ttggtgatga attggctaaa aacatcgcta aaggatttgt taatggtaaa tacgacggtg
    50581 gtcgtcacca aatccgggtt gacatgttga acaaaatggg ctaattagat tatagtaaga
    50641 aaggtaagtt aaaaatgaga attgcaattg gatgtgacca catcgtaact gatgaaaaaa
    50701 tggcggtttc agaatttttg aaatcaaaag gatatgaagt cattgacttt ggtacctatg
    50761 accatacacg gactcactac ccaatctttg gtaaaaaagt aggggaagca gtaactagtg
    50821 gtcaagctga tctcggggta tgtatctgtg gtactggtgt tggtatcaac aacgctgtaa
    50881 ataaagttcc aggtgttcgt tctgccttgg ttcgtgatat gacaacagcc ctttatgcta
    50941 aagaacaatt gaacgctaac gttattggtt ttggtggtaa aattactggt gaattgctta
    51001 tgtgtgatat catcgaagct ttcatccatg ctgaatacaa accaactgaa gaaaacaaaa
    51061 aattgattgc gaaaattgaa catgttgaaa gtcacaatgc tcaacaaaca gacgcaaact
    51121 tctttacaga attccttgag aaatgggatc gtggagaata ccacgactaa gaggtgacct
    51181 atgattttaa cagtcacaat gaacccatcc atcgatattt cctatccctt ggatgagttg
    51241 aagattgata ctatcaatcg tgtggtggat gtaaccaaaa cggctggtgg taagggactc
    51301 aatgttaccc gagtactttc agaatttggc gattctgttc ttgctactgg tttagtgggt
    51361 ggcaaacttg gtgagttttt ggttgaacat atcgataatc aagtaaagaa agatttcttc
    51421 tcaattaagg gagaaactcg taactgtatc gctattctcc acggagacaa ccaaacagaa
    51481 gttcttgaaa aaggtcctga agtattggaa caggaaggtc aagagttttt ggaacatttc
    51541 aaaaaactct tggagtcagt tgaagtagta gccatctcag gtagtctgcc agctggcctt
    51601 ccagttgatt actatgcgag cttggtagaa cttgctaatc aagctggcaa gcctgtagtc
    51661 ttggactgct caggtgcagc acttcaggct gttcttgaat caccccataa accaacagtc
    51721 atcaaaccaa ataatgaaga attgtctcag cttcttggaa gagaagtttc tgaggatttg
    51781 gatgaattaa aagaagtact tcaagaacct ttgtttgcag ggattgaatg gattatcgtt
    51841 tcacttggtg ccaacggtac ttttgccaaa catggtgaca ctttctacaa ggtagatatt
    51901 cctagaattc aggtggtaaa tcctgttgga tctggagact ctactgtggc aggaatttct
    51961 tcaggacttc ttcacaaaga atcggatgca gaattactca tcaaggcaaa tgtccttggt
    52021 atgctcaatg ctcaagaaaa aatgactggt catgtcaaca tggccaacta tcaagctcta
    52081 tatgatcaat taatagtaaa agaggtataa aatggcttta acagaacaaa aacatgtacg
    52141 cttagaaaaa ctttctgatg aaaatggtat catctcagct cttgcatttg accaacgtgg
    52201 tgctttgaaa cgcctcatgg ctcaacacca aacagaagaa ccaactgtgg cccaaatgga
    52261 agaacttaaa gtcttggtag cagatgaatt gactaaatat gcttcatcta tgcttcttga
    52321 ccctgagtat ggacttccag caactaaagc tcttgatgaa aaagctggtc ttctccttgc
    52381 ttatgaaaaa acaggttatg acacaacaag cacaaaacgc ttgccagact gcttggatgt
    52441 ttggtctgca aaacgtatta aagaagaagg tgcagatgca gttaaattct tgctttacta
    52501 tgatgtagat agctcagacg aactcaatca agaaaaacaa gcctacatcg aacgcatcgg
    52561 ttctgagtgt gtggctgaag atatcccatt cttccttgaa atccttgctt acgatgaaaa
    52621 aattgcggat gcaggttctg tagaatacgc taaagtaaaa ccacacaaag ttatcggcgc
    52681 tatgaaagtc ttttcagacc cacgctttaa cattgatgtt ttgaaagttg aagttcctgt
    52741 taacattaaa tatgttgaag gcttcgctga aggtgaagta gtttatacac gtgaagaagc
    52801 agcagccttc ttcaaagcgc aagatgaagc aacgaacttg ccatacatct acttgagtgc
    52861 tggtgtatca gctaaactct tccaagatac tcttgtattt gctcatgaat caggtgcaaa
    52921 ctttaacgga gttctttgtg gccgtgctac atgggcagga tcagttgaag cttacatcaa
    52981 agatggtgaa gcagcagctc gcgaatggct tcgcacaact ggatttgaaa acattgacga
    53041 actcaacaaa gttcttcaaa gaacagcaac ttcatggaaa gaacgcgtgt aagaaagtcc
    53101 tcctagttta ggaacatgaa tctaaaaaaa tttaaaaaaa gttgtatgta aaggtttaca
    53161 aaataactta cttgtgctat acttaaatca caagttaata tgaattagaa agtaactata
    53221 tgaagtataa taaaaatagg atatagttta ttttacgagc taggaaggaa aaaatacgga
    53281 aacaatattg ccagaataaa ctatatttag atgcacattt cactcattgt tttataaaag
    53341 gagaagataa atggctacta aaaagagttt taaagcgtta gttgtaggac taggtattgt
    53401 ttcaatattc tcatcagcct tacctatggt tagtggttct gtatttgcag atagtgccct
    53461 aactacagta gataaagcaa atgatattgt tttgaatgtt gatgggaata aattttataa
    53521 tgtttcggtt tcagaagata ttgtaaatgc tggtcaaatt ttggaagatt atttttatgt
    53581 agataaattt ggaaatataa atttaaaagg cactcctgaa gagttatcaa aaaatattgg
    53641 tatttctgta caagaagcaa gtttgatgta tgaagctgta aaagagttgc ccaacgttta
    53701 cgaaagaggt cctgtaggtt ttcgtttcaa tcttggtcct caagtgaggg ggatgggtgg
    53761 ctgggctgct ggagctttcg ctactggata tgctggatgg catttgaaac aatttgcggt
    53821 taatcctgtt acatctggat ttgttgctgt aataagtggt gcgattggct gggctgtaaa
    53881 aactgctgta gaaaattatt ggacagttgc tgtagctaca gtagaagtgc cgtttgtgaa
    53941 ccttgtttac accatagatt taccttagag gttatttctt tatgaatcat tcttttaaaa
    54001 aaataactgt attttgtttt atagtttctt gtgttctttg tttattagac ttaatgaatt
    54061 ttaaaaatgt agctactttt ttatttttct gtcttcctgt ttttgttttg atttacaaaa
    54121 ataaataaaa acagagcctc tgtttgatga attttagaac atagttaagt tttaaaaaaa
    54181 gttgtatgta aaggtttaca aaacaaccga cttgtgctat acttaaatca caagttaata
    54241 caaggtgagt gttactaagt aatattaggc atgatcacag gtgaattaga aatcagctga
    54301 ttttctagtt catttgtggt cattttttgt actcatatac ctttaagata taaaaggagg
    54361 ttgacatgta tcgaattcta aatccaatga atcacaatgt ctcgcttgtc agaaatgata
    54421 agggagaaga ggtgattata attggtaagg ggattgcatt cggaaaaagg aagggggatt
    54481 tgattgctga aaatcaggtt gagaaaatct ttcggatgaa gaccgaagag tccagagaaa
    54541 actttatggc tcttctcaaa gatgttccgc ttgattttat cacagtgacc tatgaaatca
    54601 ttgataagct atcaaagaaa tatcattatc cgattcaaga gtatctctat gtaaccttga
    54661 cagatcatat ttactgttct tatcaagctc taactcaagg aaggtacaag gatagtaatc
    54721 tgccggatat ttccgctaag tatcctgtcg cttttcaaat cgcaaatgaa gcttttgaaa
    54781 tttaccgtca gaagctagca gatcattttc ctgaggacga gattattcgg attgcttatc
    54841 atttcatcaa tgccgaaggt gaaaatgaag tggaacttgt ggagtcgatt gataagagga
    54901 aagaaattct caggaatgtt gaagaagtgc taaagggtta tgcaattcaa cgaaccaaaa
    54961 aaaataatca tttctatgat cgctttatga ttcatttgaa ttatttcttg gattatttag
    55021 acagatctag agatgataac caatcacttc tggatatgga agatcatatt aaacaatcct
    55081 atccaaaagc cttcgagatt ggttccaaga tctatgatgt gattacgcaa catacgggtc
    55141 ttgatttgta taaaagtgaa cgagtttatc tagttctaca tatccaacgt ttattgtcat
    55201 aaaaatttat ttaaaactat ataaggagaa ttctatcatg aatagagaag aagtaacatt
    55261 gttaggtttt gaaatcgtag cctatgctgg cgatgctcgt tcaaaactat tggaagcctt
    55321 gaaggctgct gaagctggtg attttgaaaa agcggacgct ctggtagagg aagctggtag
    55381 ctgtattgca gaggctcacc acgcgcaaac aagtctattg actaaggaag cttctggtga
    55441 ggacttagcg tatagtgtga ccatgatgca tggccaagac cacttgatga caactatctt
    55501 gttaaaggat ttgatgcacc atttgatcga actctataag agaggagtta aataatgaac
    55561 aaactaattg catttatcga gaaaggaaag cctttctttg agaaactatc tcgtaatatc
    55621 tatcttcgtg ctattcgtga tggtttcatt gcaggtatgc ctgttattct cttctcaagt
    55681 atctttatct tgattgcctt tgtaccaaac tcatggggct ttaaatggtc tgatgaagtt
    55741 gtagcctttc tgatgaaacc ttatagctat tctatgggta ttctggctct cttggtagct
    55801 ggtacaacag ctaagtcatt gaccgactca gtaaaccgta gcatggagaa aaccaatcaa
    55861 atcaactata tgtcaacgct gttagcagcg attgttggtt tgttgatgtt ggcagctgat
    55921 cctatcgaaa atggtctagc tactggattc ttggggacaa aaggtttgct ttcagccttc
    55981 cttgctgcct ttgttactgt agccatctat aaggtctgtg ttaagaacaa cgtcactatt
    56041 cgtatgcctg acgaagttcc accaaatatc tcacaagtct ttaaagatgt gattccattc
    56101 actctatcag tggtttctct ttatgctctt gatttactag ctcgtcattt tgttggttct
    56161 agtgtggcag aatcaatcgg taaattcttc gcaccactct tctcagcagc agacggatac
    56221 cttggtatta ccattatctt tggtgccttt gccttcttct ggtttgtggg tattcatggt
    56281 ccatctattg ttgaacctgc tatcgcagcg attacctatg caaatgctga agtcaacttg
    56341 aaccttctcc aacaaggtat gcatgctgat aaaatcctta cttcaggaac tcaaatgttt
    56401 atcgttacta tgggaggtac tggtgcgaca ctggttgttc cattcatgtt catgtggtta
    56461 acaaaatcaa aacgtaaccg tgcaatcgga cgtgcttcag tagttccaac tttctttggt
    56521 gtaaatgaac caatcttgtt tggtgcacca cttgtattaa atccaatctt cttcattcca
    56581 tttatctttg ctccaatcgc aaacgtatgg attttcaaat tctttattga aactcttgga
    56641 atgaactcat tcactgctaa tctaccatgg acaactccag ctccactagg tctagttctt
    56701 ggaactaact tccaagtgct atcattcatt cttgctgccc ttctaatcgt ggttgacgtt
    56761 gtcatttact atccattcct taaggtctat gatgaacaaa ttcttgaaga agaacgttca
    56821 ggtaagtcta atgatgaatt gaaagaaaaa gttgctgcaa acttcaacac tgcaaaagcg
    56881 gatgctattc ttgaaaaagc gggtgtagaa gcagcacaaa atacaatcac taaagaaaca
    56941 aatgtcctcg ttctctgtgc aggtggagga acaagtggtc tccttgcaaa tgctttgaat
    57001 aaggcagcag cagaatacaa tgtccctgtg aaagcagcag caggcggcta tggtgctcac
    57061 cgtgaaatgt taccagagtt tgatcttgtt gtccttgccc ctcaagttgc ttcaaacttt
    57121 gaagatatga aagcagaaac agataagctc ggtattaaac tagcgaaaac agaaggcgct
    57181 caatacatca aattaactcg tgatggaaaa ggtgccctag cattcgtaca agcgcaattc
    57241 gattaaggct agagactctg aaattgtctc ctatcgttac ggaaatcgct atggcgaatt
    57301 tcctaatcgc cttattaatt cggtgacttg gtacaagaag tgagatggag aaggatggct
    57361 cactgactcc cctcctctca cttttacttt atttaaatca agaaataggt gaaaaaaatg
    57421 acaaaaacac ttccaaaaga ctttattttt ggtggcgcaa cagctgccta tcaagcagaa
    57481 ggtgctacac atactgatgg taaaggacca gtagcgtggg ataaatatct tgaagataac
    57541 tactggtaca ctgcagaacc agccagtgat ttttacaatc gatatccagt tgacctcaag
    57601 ctagcagaag agtatggtgt caatggcatt cgaatttcta ttgcctggtc acgtattttc
    57661 ccgactggtt atggtcaagt aaatgctaaa ggtgttgagt tttatcataa tctatttgcg
    57721 gagtgccaca aacgtcatgt tgagcccttt gtaactcttc atcactttga cactccagaa
    57781 gctctccact caaatggaga cttcttaaac cgtgaaaaca ttgaacactt tgtagactac
    57841 gcggctttct gttttgaaga atttccagaa gtaaactatt ggacaacctt caatgaaatt
    57901 ggaccaatcg gtgatggtca atatttagtt ggtaaattcc ctccaggaat tcagtacgac
    57961 cttgccaaag tcttccaatc gcaccacaat atgatggtgt ctcatgcacg tgctgtaaag
    58021 ctatataaag ataaaggata taaaggggaa attggtgttg ttcacgccct gcctactaaa
    58081 tatcctctag atcatgaaaa tccagcagat gttcgtgcag ctgagttgga agatatcatc
    58141 cacaataaat ttattttgga tgcaacctat ctgggtcact actctgaaaa gactctggca
    58201 ggggtagagg ctatcttatc agtcaatggt ggtagtttgg atcttcgtga agaagatttt
    58261 acagcattag aagctgcaaa agacttgaat gatttcctag gaatcaacta ctatatgagt
    58321 gactggatgg aagcctttga tggagaaact gaaattatcc ataatggtaa aggtaaaaaa
    58381 ggaagctcta agtatcaaat caaaggtgtt ggtcgtcgtg tagctcctga ctatgtacca
    58441 cgcacggatt gggattggat tatctaccct caaggtttgt atgaccaaat catgcgtgtg
    58501 aagaaagatt atcctaacta caagaagatt tacatcactg aaaatggtct cggctataaa
    58561 gatgagttcg ttgataacac tgtttacgat gatggtcgta ttgattacgt gaaacaacac
    58621 ttggagatct tgtctgatgc gattgcagat ggagctaatg taaaaggtta cttcatttgg
    58681 tcattaatgg atgtcttctc atggtcaaac ggttatgaga aacgttatgg tctcttctat
    58741 gtagactttg aaactcaaga acgttatcct aagaaatcag ctcactggta caagaaagta
    58801 gcggaaactc aagtaattga gtagtagaat tagtaattag atatagaatt ttagtgaggc
    58861 aaaaagatgt tcaaagattt tatccaatct atttatgaaa aagtttatat tatcaatttt
    58921 gataaatgtt ctcaaatacc gtgtttgacg aatgaagaac tgaaaagtct cggaaaatgg
    58981 tatgtctata ccggtaaaga atggatttgc cattcagact atgagctgga agaatttaaa
    59041 aatatctttt taaattttat caatcctgaa gaatgggata ctatctcctt tgattcagat
    59101 tttatgccgt tttaacaatc gtaaccaatt tccaaaaaag ttaaatctcg tatttagtac
    59161 gctgcaaaac tcttatctaa tcacgttgct tatactcaat gaaaatcaaa gagcaacttt
    59221 aaactagaaa gcgagtcgca ggtttctcaa tgcatcgctt tgaggttgca gataaagcaa
    59281 ttaggcaaaa agtctttaac gcagaaaaac gcataatatc aggtttaaaa aaccttgata
    59341 ctatgcgttt tattgtggga agatttactt ctgaaattga gttgttaccc agaatctttc
    59401 agtttattaa ggcttgatga ctttagtaag tttagatagt tcaaaaagga ttgaatcact
    59461 tagtttagaa tctgaaacaa tagtatcaag atttgataca ttataaaaag tataaaaatc
    59521 aaacttattg aacttactat gatctgcgag taaatatttt ttattagaat tatttaaagc
    59581 gatgcgttga gcctctccct cttcctcgct aaaagtagct agagctccgt tttgaatacc
    59641 attacagcta acgaaagctt tagaaaattg gagattagag agattttgta gggtcaatgt
    59701 gccaacaaaa gcacctgtaa tatcgcgata atttccacct atcaaaatca aatctgttaa
    59761 ttttcgttcg cttaaaatca gaaaaacagg tagactgttg gtcacgacgc ggatattgtc
    59821 aataggcaac tcacgcgcaa aaaattctaa tgttgttcct ggtccaatga aaatagtttc
    59881 tctttcttct actagactgc ctgcaaaacg ggctatttct tgtttttctg ccgtttggag
    59941 ggcttgtttt tcaatatttg atcgctcatt agtcaaaagg gagttggttc gaagtttttc
    60001 agctccacca tgcacacgaa tcagcaaatc tttatcagct aattcctgta aatagcgcct
    60061 tgcagtcata tctgaaacgg ctatttcgtc cataatctgt ttaaccgtta tggttccttt
    60121 actatttact atctctaaaa ttttggttaa tttttcttgt ttgagcatat tatcacctcg
    60181 tttcctacta ctatcttacc ataaactagc tcatcattca aatacaaaaa caacaaaata
    60241 aaacaaaaac aaaaatatcg aggtttattt tcaaaacttt cgatattttt attaagttat
    60301 tattttgttg tttctagttt actttttgat gattgagagt ggtggagaat tatactcaat
    60361 gaaaatcaaa gagcaaacta ggaagctagc cgtaggttgc tcaaaacaca gttttgaggt
    60421 tctagataag actgatgaag tcagtgagca tatctacggc aaggcgaagc tgacgtggtt
    60481 tgaagagatt ttcgaagagt attagtccaa accgtagttg tagtcattgt cttgcatggc
    60541 ttcaacttca ccaaggaggt aaccatttcc gacttgagag aagaagtcgt ggttagatgt
    60601 tcctgttgaa ataccgttca taacgattgg attgacatca tctgctgaat ctgggaagag
    60661 tggatcttgt cccaggttca tgagagcctt gttagcattg tagcgaagga aggttttgac
    60721 ttcttccgtc caaccaacac cgtcatagag gctttctgtg tagccttctt cattttcata
    60781 aagagtatag agcaggtcgt acatccattc tttgagtttt tcttgctctt cttcaggtaa
    60841 ttcattgaaa ccaagttgga atttgtaacc aatgtaagtt ccgtgaacag actcatcacg
    60901 aataatcaat ttgatgattt ccgcaacgtt ggccaacttg ttatttccta gatagtagag
    60961 gggagtgaag aaacctgaat agaagaggaa ggtttcgagg aagacactgg caactttctt
    61021 ttcaagtggg ctaccgttta ggtagatttc gttgacaatc tcagccttct tttgcagata
    61081 aggattggta ttggtccatt cgaaaatttc ttcaatctca gccttagtat ttaaggtaga
    61141 aaagattgat gagtaagatt tagcatggac agattccata aattggatgt tattgaaaac
    61201 agcttcttca tgtggtgtac ggatgtctgc gcgaagggct tgaacccccg tttcagattg
    61261 catagtgtca agaagggtta aaccaccaaa aacttttccg accaagtctt tctctttgtt
    61321 tgatagtttt ctccagtcat ccaagtcatt tgacaaagga atacgtgtat cgagccagaa
    61381 ttgctccgtc agtttttccc aagttgattt gtcgatgaca tcttcgatgg cattccagtt
    61441 aatggctttg tagtaagttt ccatttgaaa tctctttctg tgtatagtat tgtgaactca
    61501 caattatttt tattttatca taattccaga ggaatatcgc acaaaaagtc ggagaaccga
    61561 cttttgaaat gttacataaa ttatgttatg acatagtaga tttgatttta tcagtgctgc
    61621 ttagggaaaa atagtgtttc tctgctagaa actaaatcac acagctttca cactggttgg
    61681 caccgacttc tccaccgtcg tctgtaaagg tacggacgta gtagatagac ttgataccct
    61741 tgttaaaggc atagttacga aggatagata agtcacgtgt cgtttgtttg ttttctttct
    61801 tccattcata aagacctttt ggaatatcac tacgcatgaa gagagtaagt gaaagtcctt
    61861 gatccacgtg ctccgttgca gcagcgtata catcgatgac tttacgcata tccatgtcgt
    61921 aggcagaagt gtagtaagga atggtttctg ttgacaagcc agcagcagga tagtagattt
    61981 taccgatttt cttttcttgg cgttcttcga tacgttgcgt aattgggtgg atagaagcag
    62041 aaacgtcatt gatgtaactg atagaaccat ttggcgctac agcaaggcgg ttttggtggt
    62101 aaagaccatc tgcttgaacc ttgtcgcgaa gttcagccca atcagcagca cttgggataa
    62161 agacatcttt gaagagttct ttaacacgtt ctgattttgg aacaaactcg cctgtaatat
    62221 acttgtcaaa gtagcttccc ttagcatagt ctgatttttc aaagttgtgg aaggtgatac
    62281 cacgttcacg cgcgatattg tttgactcaa ccaaggtcca gtagttcata agcataaagt
    62341 agatgcttgt gaattcaaca gactcaggcg atccatattc aatgagttgt tgggcaaggt
    62401 agctatgaag tcccatggca ccgagaccaa aggtgtgggc ttggctattt ccatggtcaa
    62461 tcgtaggtac agctacgatg tgtgaactat ctgtaacgaa agtcaaagca cgaaccatgg
    62521 cacggataga acgaccaaag tcaggtgaag tcatcatgtt gaccacgttg gttgaaccaa
    62581 ggttacatga aacatccgtt cccatttgaa ggaattcttg agcatcgttg atcaagcttg
    62641 gttcttggac ttgaagaatc tcagaacaca agttactcat aataatcttt ccatcaacag
    62701 gatttgcacg gttagccgta tcaatgttga ctacataagg atagccagac tcttgttgca
    62761 atttagagat ttcagtttcc aaatcacgcg ccttgatttt tgtcttgcga atatttggat
    62821 ttgcgaccaa ttcatcgtat ttttcagtga tgtcaatgta gttgaatggc acaccgtatt
    62881 ctttttctac agagtaagga ctgaagaggt acatttcttc atttttacga gccaattcgt
    62941 agaatttatc tggtactaca acaccaagtg atagggtttt gacacgaact ttttcgtcgg
    63001 cgttttcttt cttagttgaa aggaaggcga tgatatctgg gtgaaagaca ttgaggtaga
    63061 caaccccagc accttgacgt tgccccaatt ggttggagta agagaaactg tcttcgaaaa
    63121 gcttcataac aggaacgaca cctgaagctg ctccttcata acccttgata ggtgcaccag
    63181 cttcacgaag gttgctgagg gtaattccca caccaccacc gatacgtgaa agttgaaggg
    63241 cagagttgat agaacgtccg atagagttca tatcatccgt cacttggatt aggaaacaag
    63301 ataccaactc cccacgacga gcacgtccag cattcaagaa ggaaggagta gcaggttggt
    63361 agcgttggtg gatgatttca ttggcaatat cgattgcaac agcttcattc ccatcagcga
    63421 aataaagggc gttaaagaag acacggtctt ccatactttc aagatagtat tcaccgtcat
    63481 tagtctttaa ggcatattga ttgtaaaatt tataggcagc catgaaagac ttgaattgga
    63541 agttttggtc tttgataaat tgagccaatt cttccaagaa ctctggacgg tatttcttga
    63601 taaaggctgt ttcgatgtag ttgtgttcaa tgaggtaatt gattttgtct ttgattgaat
    63661 caaaaaccat agtgtttgga actacatttt ctttaaagaa agcatccaag gcttccttat
    63721 ctttatgaag catgatttgt ccattaacag gacggttgat ttcgttatta agacggaagt
    63781 aagtcacgtc ttcaagatgt tttaatccca taaaatttcc cttatctaat tacaaaagaa
    63841 aggcttctaa gttagcccta aaagcagttt cttctggatg atgtactaag attatgctaa
    63901 ttgtttcagt tttcctggtt ggaaacctga aaagacttca gttggtgttt ggataacagg
    63961 agctgcgcta aaaccgagct ctttaacttg atcgacgtac tcaggttgct catcaagatt
    64021 gatttcacga taagagacat tattactgtc caagaaacgc ttggtcattt tacattggac
    64081 acaattgttt ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa tttaatacta
    64141 tcttagtata tcagaaaata aaattttgtc aatgatttga actaaatata gtggtgttct
    64201 tttgttgttt ttatatacaa acacaatata tagtgtttgc gttgtgaata gcaatgatta
    64261 tcctataaat tgtttttgaa gaaactatat cctgtgtttt gttatctagg atagaagatt
    64321 ttcagcaagt tatctgaaag gaaattgaag gaaaatccag aaaatgcttg aaaaaaatcc
    64381 tagaagatgg tataatacca aattgtaagg gttatcacat ataactcaaa aaaagaaaga
    64441 acaaaaggag agtcaaacta tggcttctaa agatttccac gtagtggcag aaacaggtat
    64501 tcacgcacgt ccagcaacat tgttggtaca aactgctagc aaatttgctt cagatatcac
    64561 tcttgagtac aaaggtaaat cagttaacct taaatcaatt atgggtgtta tgagtcttgg
    64621 tgttggtcaa ggtgctgacg taactatctc agctgaaggt gcagatgcag atgacgctat
    64681 cgctgcaatc tcagaaacaa tggaaaaaga aggattggca taagggaaat gacagaaatg
    64741 cttaaaggaa tcgcagcatc tgacggtgtt gcagttgcaa aagcatatct actcgttcag
    64801 ccggatttgt catttgagac tattacagtc gaagatacaa acgcagaaga agctcgcctt
    64861 gatgccgctc tacaggcatc acaagacgag ctttctgtta ttcgcgagaa agcagtaggt
    64921 acgctcggtg aagaagcagc tcaagttttt gatgctcact taatggttct tgctgaccca
    64981 gaaatgatca gccaaatcaa ggaaactatc cgtgcgaaga aagtgaatgc agaagcaggt
    65041 ctgaaagaag ttacagatat gtttatcact atctttgaag gcatggaaga caacccatac
    65101 atgcaagaac gcgcagcgga tatccgcgac gtgacaaaac gtgtattggc aaaccttctt
    65161 ggtaaaaaat taccaaaccc agcttctatc aatgaagaag tgattgtgat tgcacatgac
    65221 ttgacaccat ctgatacagc tcaattggac aaaaattttg taaaagcttt tgtaaccaac
    65281 atcggtggac gtacaagcca ctcagctatc atggcacgta cacttgaaat tgcagctgta
    65341 ttaggtacaa acaacatcac tgaaatcgtt aaagacggtg acatccttgc tgttaacggg
    65401 atcactggtg aggttattat caacccaact gatgaacaag cggcagaatt taaagcagct
    65461 ggtgaagctt atgcgaaaca aaaagctgaa tgggcgctct tgaaagatgc tcaaacagtg
    65521 actgctgacg gtaaacactt cgagttggct gctaatatcg gtactccaaa agacgttgaa
    65581 ggtgttaaca acaacggtgc agaagctgtt ggactttacc gtacagagtt cttgtacatg
    65641 gattctcaag acttcccaac tgaagatgag cagtatgaag catacaaggc tgttcttgaa
    65701 ggaatgaacg gtaaacctgt tgtcgttcgt acaatggata tcggtggaga taaggaactt
    65761 ccttacttcg atatgcctca cgaaatgaac ccattccttg gattccgtgc tcttcgtatc
    65821 tctatctctg agactggaga tgctatgttc cgcacacaaa tccgtgctct tcttcgtgcg
    65881 tctgttcacg gtcaattgcg tatcatgttc ccaatggttg cgctcttgaa agaattccgt
    65941 gcagcgaaag cagtctttaa tgaagaaaaa gcaaaccttc ttgctgaagg tgttgcagtt
    66001 gcggataaca tccaagttgg tatcatgatc gagattcctg cagcggctat gcttgcagac
    66061 caatttgcta aagaagttga cttcttctca attggtacaa acgacttgat ccaatataca
    66121 atggcagcag accgtatgaa cgaacaagtt tcataccttt accaaccata caacccatca
    66181 atccttcgct tgattaacaa cgttattaag gcagctcacg ctgaaggtaa atgggctggt
    66241 atgtgtggtg agatggctgg tgaccaaaca gctgttccac ttcttgtcgg aatgggcttg
    66301 gatgagttct ctatgtcagc aacatctgtc cttcgtacac gtagcttgat gaagaaatta
    66361 gatactgcta agatggaaga gtacgctaac cgtgccctta cagagtgttc aacaatggaa
    66421 gaagtccttg aacttcaaaa agaatacgtt aatttcgatt aatgtcatta accttgtaac
    66481 ctagttgcaa ggtttttttg acgcattttg gaaaagtatg gtcttataaa gtccactttt
    66541 caatgagtca gaggcatgat ataatagggg gaaacaaata gaataagaga gaaaccatgt
    66601 ctaaagaaat tgatattgag tattaccatc agctagcctt gcaaaagcag aaggagcatc
    66661 gaaaagtttt agccaatcta aagaaaaaac ctcctaaaaa cctagacaag atagcccagc
    66721 agattcacca agaagtcttt gaggagattg attgtaccgc ctgtgctaac tgttgcaaga
    66781 cattgggacc tgactttaaa gaagcggata ttactcgtat tgccaagtat tttaagatga
    66841 aattaccagc ttttgaagcg gagtttctgc aggtagatga agatggggac aaggttttca
    66901 aatccatgcc ttgcccattt ttaggaggag ataatctctg ctctatctat gatgttcgtc
    66961 caaaggcctg tcgtgaattc cctcatactg accgcaaaaa gatccatcaa atcaaccatc
    67021 tgacgattaa gaataccttg acctgtccag cggcctatct ctttgtggag aaattaaagg
    67081 ataagttgta gagatttaaa ggataaaaaa tctctaataa taactaggga tatgaaagga
    67141 gtactcctat gcctagacca aaaacaaaag aggagctagt gctagcctct aaggaaaact
    67201 atgacaagct caaccgtttc atctcccaac taagtgaaga tgagctacag actccatttg
    67261 atttttcaaa agaccaaaag aaaaaggaag cgcactggaa aagagataaa aatctaagag
    67321 atgttctgat ccatctctat gaatggcagc agttactttt gacttgggta cattctaatc
    67381 aaaaggggca tgagagacct tttctccctg aaccttataa ttggaaaact tatgggaaga
    67441 tgaatgtcac tatttggaaa aagcaccaga aaacctcctt agaagaagcg actagactcc
    67501 tagaacaatc acatagagag gttttagagt tgatggaagg cttcagcaat gacgaactct
    67561 ttgccaaagg tatctataag tggacgggag gaacaagtct aggttcctac tttgtcagta
    67621 gcacctccag tcactatgat tgggctctaa aaaagatcaa agcacatcag aagaattgta
    67681 aaatgcagat ggactctttg aaaaagaatg aattctttta aacatgagat aagattaaaa
    67741 gggctatcaa gtgacgtagc ccttttgagt tatagaatag aattaccatg caaaagctgt
    67801 cgttggagca ttgagcgctt ttaaccattg tttatttttt acagggcaaa gagttacgga
    67861 tatacctgcc atatccagac tggtcataaa tgttcctgat tttataaagg taatagtgac
    67921 tccttcaatt tctaagagtt gaaggatatc attgataaat atgcccattt ctaggttgct
    67981 agtagtgcct agattattta caagcaatat aaattgatca ccctttttcc aatgatagtg
    68041 caatcttaat ttgcttataa tttcatttgc caggatttcc gatgattgaa atgggacaat
    68101 acgataacct tcttcaccgt gtatcccaat accataggaa atatttcctt cttccaagtt
    68161 aaatagtgga agggtggctt gagggaggct agcagatttc gttgcaaagc caattgttgc
    68221 gatttcggga gcaagttcat gacctaaatc agttagttgc tcgatgtcgg caccattttg
    68281 agctgcatat cctagaactt tatgaagtaa aatagtccct gcaagccctc ttcctctaat
    68341 ttgaaatcta ttgtgaggtt caatagaaat atcgtcgtgt gctagactat agccgacctt
    68401 aattccttct tgtctagcag tattaatggc ccagctaaat tctttgatgt ctgcttcgaa
    68461 attttttaca atgatgaaga caccgtgacc attgtttaaa aaacgaatgg actctaagat
    68521 ttcagttctt gtaggaggag taaataattg gccatagata gcagcggtaa gcatgccttc
    68581 tcccacatat ccaatatgcg caggttcgtg accggaacct ccacccgaca atattggaac
    68641 ctgatgagga ttgcgatttt tttgatagac tagtggtaaa gtagggtgtt tttctaattc
    68701 aggatgactg ctgacagttg ctgaaatgta acttgaaata attttttgtt tatgatttga
    68761 aataaatgtc attgtggtct ctttccaata attgtcatga ttagaaagtc tggttgtgga
    68821 actggacttt ttttattgac gtaagccttc acgatttctg ctagagcatg tgaatgatag
    68881 tctaacaaaa aacaagtata ggcagatgaa tcgatatcaa tctgaccata ttctcttaaa
    68941 atttttgata caagcaagcg acagtagctg ataaattggt catagaagtt attttgccct
    69001 tgaatatcaa aaagttgaat ataaaagtca cgctcttgtt cgaaataaag aaataattct
    69061 tgtaatagtt tttggcccga aatgaagtcc aagttattgg taatatactc ggttaagtca
    69121 gtttcaaaaa tccagtctag cagttcatat ttgtcaagaa agtgattgta aaaggtctgt
    69181 ctacgaatgc cagctgattc catgatatct acaatagaga ttttgtcaaa ttctctagta
    69241 gctaataggt ctctaaatgc cttggcaatc cgtttttttg taatgagtga tgatgccata
    69301 ggaagccttt cttttactta cttcatttta ccaaaaaaat gttttaaacg ggtttaaaag
    69361 gggacaaata atagaatctg tcccttatca tccagcaata aaaaatatat aatgaaagcg
    69421 aaaacaaaag taaatgccga aaggagtttc tcatgaaaaa aattataaat aaaccgacac
    69481 aagttgttga tgaaatgttg caaggattgt cattcatgca tgatgacttg gtagaacgct
    69541 tagatggttt tgatgtcatc gttagaaagg tagaaaagac aggaaaagtt ggactcattt
    69601 caggtggagg ttcaggacat gaaccaagtc atgctggatt tgtaggagat ggaatgttgt
    69661 ctgctgccat ttgtggagca gtcttcactt cacctactcc ggaccaaatt ttagaagcca
    69721 tcaaggcggc tgatgaaggt gctggagttt tcatggtcat caagaactat tctggtgaca
    69781 ttatgaactt tgaaattgca caagaacttg ctgaaatgga aggtattgat gtagcaagcg
    69841 ttgtggttga tgatgatatc gctgttgaaa atagtctcta tacccaaggg cgtcgaggtg
    69901 ttgcaggtac tatattagtc cataaaattt tgggggctgc agctcgttct ggtaaatcat
    69961 tatctgaaat gaaggacttg gccgataaac ttgtcttaga aattaaaaca attgggctag
    70021 ccctgtctgg agcaaccgtt cctgaggttg ggaaaccagg atttattctg gaagatgatg
    70081 aatttgaata tggagttggt attcatggtg agccaggata taagaaagag aaaatgcaac
    70141 cttcagcaca attagcctca gaattggttg aaaaactatc tgaaggtttc caacttaaag
    70201 ctggtgaacg ctatgggctt ctcatcaatg gtttaggaag cacccctctt atggagcaat
    70261 acgtatttgc aaatgatgtg gctaaattac tccatgaaaa aggtgttgag ttgtcattta
    70321 agaaaattgg gaactatatg acctcaatcg atatggctgg cttgtcattg acattgattc
    70381 gattggcaaa tgatgaatgg ttggatgctc taaatgcacc tgttactaca ccagcttggt
    70441 aaaactcaag gaggaaatgt cgcataaatg ctgaacaagc acttgaatgg atgaagcttt
    70501 ttaatgaaaa gattcaagaa cagaaagatt accttagtga gttagacact cctatagggg
    70561 atggagacca cggtggaaat atggcgcgtg gaatggctgc agttatggaa aatttagaag
    70621 gaaagcaatt tgagacaagc agtgatgtgt ttaaagttgt ttcaatgcaa ctactgagta
    70681 aggtaggcgg tgcttctggt cccttgtatg gctctgcttt tatgggaatg tccaaggctg
    70741 attctcattc aaaattagaa gaaatcttac aaagtggttt ggatatgatt gtcaaacgtg
    70801 agaaagcagt agttggagag aagacaatgg ttgatgtttg gactcctgct attgctgcct
    70861 tgtctgatgg ccaattgact catgagctta ttgataaggt agtgaatgct accaaagatt
    70921 tacttgcaac taaaggaaga gcatcttatg taggagaacg ttctcttgga catattgatc
    70981 ctggatcatt ctcatcagga ttactcttta ctgctatttt agaaactggg gtggtttgat
    71041 ggaaagtatt ggtcttgtta tcgtttcaca ttccaaaaac attgcagaag gtcttgttga
    71101 actgattagt gaagtagcta aagatgttcc aattacttat gtaggaggaa ccgaagatgg
    71161 aggaattgga acaagttttg atcaagtaga tagggttgtt tccgaaaatc cagcagatac
    71221 tttattagcc ttttttgacc taggttctgc taaaatgaac ttagaaatgg tggctgattt
    71281 cagtgataaa agtatcatga tcaatagggt tccaattgta gaaggtgctt atactgcagc
    71341 tgctcttctt caggctggtg cagaactgtc agttattcaa acacagttgt cggagcttga
    71401 aatcaataaa taaggaattt tactataaca ctttttatag gtgggctatt gattatctca
    71461 actatcaaat tttaagtaaa taaaaaggga ttgctttggg cagttccttt ttattttaac
    71521 aagagtaaac ctatagtgtt tctaaattgt gaatcattca aaactgattg tgatgagact
    71581 attctagctt tagaatcctt caaaaattaa agtttaaggc aatcaattac ttagaagagt
    71641 acgaaaacat ttagtttata ggaattctag gtttagaatc acatggatat ttattaagtc
    71701 agggtgttcg atagttagga ttgttctatt ctgaaagatt tgagctgtca attgtatagg
    71761 atagtgttcg aatttttttc aagtgattaa attagttaat tgtatgaggt gctttatgat
    71821 ataatgttct taatgaattt tcagaaagga aaacctcaaa ttgtcctaca aatttctact
    71881 cttcgacctc gaccacactc ttcttgattt tgatgctgct gaggatgtgg ctttgaccca
    71941 acttctaaaa gaagaaggag ttgcggatat tcaggcttat aaagattatt acgttcctat
    72001 gaacaaggct ctctggaaag acttggagct gaagaaaatc agtaaacaag agctggttaa
    72061 cacgcgcttt tctcgtttat tttctcattt tggacaggga aaagatggta gttttcttgc
    72121 ccaacgttac caattttacc tcgcccagca gggacaaaca ctatcgggcg ctcatgatct
    72181 cttggacagc ctcattgatc gtgattatga cttgtatgct gcgacaaatg gcattactgc
    72241 cattcagaca ggacgtttgg ctcaatctgg tctagaacct tatttcaatc aagtctttat
    72301 ctctgagcaa ttgcaaactc aaaagcctga tgctctattt tatgaaaaaa tcggtcagca
    72361 gattgctggc tttagcaaag aaaagacgct gatgattgga gattctctaa ccgccgacat
    72421 tcaaggtggc aataatgctg gaattgacac gatctggtac aaccctcatc acctcgaaaa
    72481 tcacacacaa gcccagccaa cttacgaagt ccattcttac caagacttgc tggattgttt
    72541 ggataaaaat attcttgaaa agattacatt ttaaaggata cgagctaatg actacaaaaa
    72601 aagctaatat tactattgaa gagtacattg aaatgtctga agttgatttt aatgaaactg
    72661 ttaattatga atttacatct gacacttgtc aattagcaaa tagtatttat caatctcttt
    72721 ttaagttttt tgataagaaa aatttctctg gcgatttaat ttttacttgg aaatctccat
    72781 cattagtcaa agaaggggat tatattggga gaagggattc acaagtagat aatcttagag
    72841 taataggaaa tatatttccg aattatctta ctaatcgaaa atatagcctc aatatgaatc
    72901 gtaatggctg tatgggagat tttcctcatg acttttttga tatataccta gatcatgtag
    72961 caaaatatgc ctacgaacaa aaagttaata atattaaaga gtattatcct ttaaactgta
    73021 aaaagtggtt tagatagcca ctttttgcta taatagaggc agtaaaaacg aaggagttgg
    73081 ctatggaaca ctcgtcttgg catgctttga taaaggaaca attgcctaaa ggttatttcg
    73141 ggaaaatcaa tcagtttatg gaacaggtct atgctcaggg aactatttat ccacccaagg
    73201 aaaaggtttt tcaggctctc ttgacaacac cgcttgaaga agttaaggta gtgattctag
    73261 ggcaagaccc ctatcacggg ccaggtcaag cgcagggctt gagtttttct gtacctgact
    73321 ctatcccagc tccgccatcc ttgcaaaata tcttgaaaga attgtcagat gatatcgggg
    73381 ttaagaaatc tcatgatttg acagcttggg ctgaacaagg agtcttgctt cttaacgctt
    73441 gtttgacggt tcctgctgta caggccaatg gtcatgctgg gcagatatgg gagcctttta
    73501 cggatgctgt gattcaggtg gtcaatcaat tagataaacc agtagtcttt atactctggg
    73561 gagcttatgc acgcaagaag aaggccttag ttaccaatcc tcaccatctg attatcgaat
    73621 cagcccatcc aagtcctttg tcggtttata gaggattttg gggttccaaa cctttttcca
    73681 aggccaatgc attattaaaa gagacaggac aagagccaat cgattggctt agataaggag
    73741 aaaatatgcc tcagttagcg acaatttgct acattgataa tgggaaagaa ctgctcatgc
    73801 tccaccgtaa taagaagcca aatgatgtcc atgaagggaa atggattggt gtgggtggta
    73861 agctagagcg tggtgagacg cctcaggaat gtgcagcgcg tgaaatcctt gaggaaacag
    73921 ggctcaaagc caagccagtt ctaaaaggtg tcatcacttt tcctgaattt acaccagatt
    73981 tagactggta cacctatgtt tttaaagtga cggagttcga gggtgactta attgactgta
    74041 acgagggaac gctagaatgg gttccctatg atgaagtttt gagcaagcca acttgggaag
    74101 gtgaccacac ctttgttgag tggcttttag aggacaaacc cttcttttca gccaagtttg
    74161 tttatgatgg ggataaattg ttggataccc aagttgattt ctatgaataa aggagaaagc
    74221 agatgctact aattaaaaat ggtcgtgtaa tggatcccaa atctggtttg gatcaagtgt
    74281 gtgatgtctt agttcaagat gggaaaatta tcaaaattgc gcctgaaatc actgaagaag
    74341 gagcagaaac gattgatgct agtggtcttg tggttgctcc tggtttggtc gatattcatg
    74401 tgcatttccg tgaacctggt caaacacata aagaagacat tcatactggt gccctagcag
    74461 ccgctgcagg tggttttaca actgttgtca tgatggctaa tactagccca accatttcag
    74521 atgtagagac tttgcaagaa gttctccagt cagctgccaa agataagatt aatgttaaga
    74581 cggttgcgac cattactaaa aattttaatg ggcaagattt gactgacttt aaggcacttt
    74641 tagaagttgg agcagttgga ttttcagatg atggcattcc acttgaaagc agtaaagttg
    74701 tcaaggaagc catggaggaa gccaaaaaac tcaatacctt tattagcctt catgaggaag
    74761 atccaggatt gaacggtgtt cttggcttta acgaaaatat tgctaaagaa cattttcata
    74821 tctgcggtgc tactggggtg gctgagtatg ctatgatggc gcgtgatgtc atgattgcct
    74881 atgcaaccaa ggcccatgtt catattcagc atttgtctaa ggaagaaagt gttaaagtag
    74941 tggagtttgc tcaaggtttg ggtgcgcaag tcacagcaga agtagcgcca cagcattttt
    75001 ctaagaccga agcgctcctt ttgacacaag gaagtaatgc caagatgaat ccgccgcttc
    75061 gtttggaatc agaccgtcgt gccgtgattg aaggtctcaa gtcaggtgtc atcacagtta
    75121 ttgcgactga ccatgcgcct catcatgtag atgaaaaaaa tgttgaggat attaccaaag
    75181 cgccatctgg tatgactggc ttagaaacct ctctgtctct cggtttaact tatttggtgg
    75241 aagctggtga gttaagcttg atggaattac ttgaaaaaat gacatacaac ccatccaagc
    75301 tttacaattt tgaagcaggt tacttggctg agaatggtcc agcggacatc actatttttg
    75361 atgctaaggc tgaccgcctt gtggactccc attttgcttc gaaagcagct aattcaccat
    75421 tcatcggtga aaccttaaaa gggcaggtta aatacaccat ctgtaaggga caaatcgtct
    75481 atcaagcttg ataggagttg gaatatgaat tattttcgaa aacgtaggga gagacaagca
    75541 aaatctaata gcggaattta ctgtcccgca tctaatcgtt ctaaaattca atatgaaact
    75601 aaagaaaaag ctgaccatgc ggttcaatat gataacggag gtttagttag aagctattat
    75661 tgtcgtacat gtgcgtgttg gcatactact tcaaaatcta ataaacctcc gctaagtttg
    75721 aaaaactatg gtctgaaact ctttggttta gataaatcag aatagaaaga gaagtatgta
    75781 taagacaaag tgtttacgag agaagttagt attattttta aaaattttct tcccaatcct
    75841 tatctaccaa tttgccaatt attctgcctc ttttgttgat actgcaatga caggtcaata
    75901 caacactatg gacttggctg gtgtatctat ggcaaccagt atctggaatc ctttctttac
    75961 atttctaaca gggattgtgt cagccttggt gcctatcatt ggtcaccatc ttggtcgagg
    76021 caaaaaggaa gaagttgcgt ctgattttta ccaatttatt tatttggcct tgggcctatc
    76081 tgtggtcttg ctggggatgg tacttttctt ggcaccaaca atcttgaatc atattgggtt
    76141 agaagcagca gtagcggcag tagcggttcg ctatctttgg tttttatcta tcgggattat
    76201 ccccttgttg ctctttagcg tcattcgttc cttgctggat tcgctgggct tgaccaaact
    76261 gtccatgtac ctcatgcttt tgttactccc tctcaatagc ggatttaact atctcttgat
    76321 ttacggtgcc tttggtgttc cagaactggg aggggctggt gctggtttag gaacatcctt
    76381 ggcctactgg gtcttgcttg ggatttctgt tctggtttta tttaaacagg agaagctcaa
    76441 agccttacac cttgagaaac gaattccact taatatggat aaaattaagg aaggcgttcg
    76501 tttaggtctg cctattgggg gaactgtctt cgcggaagtg gctatctttt cagtagttgg
    76561 cttgattatg gctaagtttt cgtccttgat tatagctagt caccagtcag ctatgaactt
    76621 ttcaagtctt atgtacgcct ttcctatgag tatctcatcg gctatggcta ttgtcgtttc
    76681 ctatgaagtg ggagccaagc gatttgatga tgcgaaaacc tatattggtc taggaagatg
    76741 gactgccctc atttttgcgg ccttcacctt aaccttcctt tacattttta ggggaaatgt
    76801 ggccagtctt tatggtaacg acccaaaatt tatcgatttg acagcgcgtt ttttaactta
    76861 tagtcttttc ttccagttag cagatacctt tgcggcgccg cttcagggaa ttttgcgggg
    76921 gtataaggat acagttattc ctttttacct tggtttgctt ggttattggg gcgtagcaat
    76981 ccctgtggct acgctatttg attccctaac agattttgga gcttattctt actggatcgg
    77041 cttgattatt agtttgattg tgagcggggc gctctaccgt tggcgtttaa ctgtgattat
    77101 gaagagattt gaatctttag caaaatccaa acgctaaaaa gtttgtgaaa aaatattctt
    77161 gacaagaaaa tcccttgttt ttacggggtt ttctttttta ttttgtgaaa tttcttttag
    77221 aaaaactttg acagtatttg ccaaaagcgg taaaatagta aggtaagaag aaagttagaa
    77281 aggcaagaag atgtcaactt tagataaaaa tcttttgcta gaaatgttcc gtaagatgga
    77341 agaaatccgt tgcatggact taaaaattgc acaattagta aagaaaggga aagtgccagg
    77401 aatgacgcac ttttctgttg gtgaagaggc agctaacgtg ggggctatgt tagctctcaa
    77461 tccagatgat ctgattacct caaaccaccg tggacacggg caagctattg ctaaagggat
    77521 tgacctcaac ggaatgatgg ctgaaatcct tggtaaatac actggaacct gtaaagggaa
    77581 aggtggatct atgcatatcg ctgaccttga tgctgggaac cttggtgcca atggtatcgt
    77641 aggtggtggt atggggatcg ctgtcggtgc agccctcagt cagcaaatgc aaaataccgg
    77701 taaaatcgtt gtttgcttct ttggagatgg tgcgaccaat gaaggtgttt tccacgaagc
    77761 agtgaacatg gcttctatct ggaacctgcc agtcattttc tattgcatta acaacggtta
    77821 cggtatctct gcggatatca agaaaatgac caatatagaa catatccatc aacgtagcgc
    77881 cgcttatgga attcctggaa tgttcatcga agacggtaac aatgtcatcg atgtctatga
    77941 aggatttcag aaagctgtag accatgttcg cagtggcaat ggtccagtct tgattgaaag
    78001 tgtaacttat cgctggctcg gtcactcatc atctgaccct ggtaaatatc gtacgcgtga
    78061 agaagtggaa ttgtggaaac aaaaagatcc aatcgaaaac ctccgcaatt accttattga
    78121 aaataacatt gcaagtgccg aagaattgga agaaatccaa gcgcaagtaa aggaagcagt
    78181 agaagcttct gttaaatttg cagaggaaag cccattccca ccgcttgaat cagtctttga
    78241 agatatttac gcagactaag gagaaagaga taaaatggaa acaaaaacaa tgtccttccg
    78301 tgacaccatt atccttgcta tgtctgagga aatgcgtcgc gatgaaaatg tgttcttgat
    78361 gggagaagac gtcggtgtct ttggaggaga cttcggtact tctgttggaa tgcttgaaga
    78421 atttggtcca gaacgtgtcc gtgactgtcc gatttctgaa gctgccatct ctggagcagc
    78481 agcaggagca gccatgacag gacttcgtcc aatcgtcgat atgaccttca tggacttctc
    78541 tgttattgcc atggacaata tcgtcaacca agctgctaaa acacgttaca tgtttggtgg
    78601 taaaggtcag gttccaatga ctgttcgttg tgcagctggt aacggagttg gctctgccgc
    78661 ccagcgctca caatctcagg acttaaggtt gtggcacctg gaacacctgc ggacatgaaa
    78721 ggcctgctta agtcttctat ccgtgataac aacccagtta ttatacttga gtacaagtca
    78781 gaatttaacc aaaaagggga agtgccagtt gatccagact acacaattcc acttggggtt
    78841 ggtgaaatca aactccaagg aacggatgta acagttgtta cttatggaaa aatgcttcgc
    78901 cgtgtggttc aagctgctga agaattagca gaagaaggaa tttcagttga aattgttgac
    78961 ccacgtaccc ttgttccgct tgataaggat atcatcataa actcagtgaa gaagactggt
    79021 aaggttgttc tggtcaacga tgcccacaaa acaagtggct atatcggtga aatttcagct
    79081 attatttcag aatcagaagc atttgactat ctagatgcac caatccgccg ttgtgcagga
    79141 gaagatgtgc cgatgcctta tgcacaaaac ctagaaaatg caatgattcc aacagttgaa
    79201 agtatcaaag atgcaatccg aaaaacttat aacaaagaat agagttacat aatataagtt
    79261 atgtaactaa aacaaagctg acgagaaact ttatatcttt taggtgcaga gctcttcgtc
    79321 attaatatct tagattagag cacgggctaa aagctcggaa aaaagataaa tctccttggc
    79381 ttcatcgaag ccaaggagat ttcctatttt tcagtcgctt ttgacgccct ttgtatcata
    79441 aatagaattg gagagatcat ggctgatgac aagctaagag cgactcctgc agctagaaag
    79501 ttagcggatg atttagggat aaacctctac gacgtttctg gctcaggtgc aaacggtcgt
    79561 gtccacaaag aagacgtgga aacttataaa gacacaaacg tggttcgcat ttcgccactt
    79621 gcaaaacgaa ttgccctcga acataacatt gcttggcagg aaatccaagg aaccggtcat
    79681 cgtggtaaaa tcatgaagaa ggatgttttg gccctgcttc ctgaaaatat cgaaaacgat
    79741 agcatcaaat ctcctgctca gattgaaaaa gtggaagaag tccctgataa cgtaacacca
    79801 tatagtgaaa ttgagcgtat tccaatgaca ccaatgcgta aggttattgc ccaacgcatg
    79861 gttgaatctt acttgactgc gccaaccttc accctcaact atgaagttga tatgactgaa
    79921 atgttggctc ttcgtaagaa ggttcttgag ccaatcatgg aagcaactgg gaagaagact
    79981 actgtaacag accttctttc gcttgcagtt gttaagactc ttatgaaaca cccatacatc
    80041 aacgcttcat tgacagaaga tggcaagact attatcactc acaactatgt caatcttgcc
    80101 atggcagttg ggatggataa tggattgatg acacctgttg tttacaatgc tgagaagatg
    80161 agtctttcag aactggttgt agcctttaag gatgttattg gccgtacctt ggatggtaaa
    80221 ttggctccaa gtgagttaca aaattcaaca ttcacaatca gtaatttggg aatgtttggt
    80281 gttcagtcct ttggtccgat tattaaccaa cccaactcag ctatccttgg tgtcagttcg
    80341 acaatcgaga agccagttgt cgtcaatggt gaaattgtga ttcgcccaat catgagttta
    80401 ggattaacca ttgaccaccg tgtcgtagat ggtatggctg gtgctaagtt tatgaaggac
    80461 ttgaaagagt tgattgaaac gccaatctca atgttaattt aagagcaaga gtattcattt
    80521 ttaagatata gataaaggaa gcaagacatg gccttagaag taattatgcc aaaagtcggc
    80581 gtggatatga cagaaggaca aatcgtccaa tggaataaaa aagtcggaga atttgtaaaa
    80641 gaaggagaaa tccttttgga aatcatgact gataaagtca gcatggaatt ggaagccgaa
    80701 gaagatgggt acttgattgc cattctcaaa ggagatggtg aaactgtccc tgtaacggaa
    80761 gttatcggtt accttggtga agaaagggaa aacatcccaa cagctggagc agcatcgcca
    80821 gaagctagcc ctgtacctgt agcaagtacc tcaaacgatg atggtaagag cgatgatgct
    80881 tttgatatcg ttgtgattgg tggaggtcct gctggttatg ttgcagccat taaagctgcc
    80941 caattcggcg gtaaggttgc ccttgttgag aaatctgaac ttggtggaac ctgcttaaac
    81001 cgtggatgta ttccaaccaa gacctacctt cataacgctg aaattattga aaatatcggt
    81061 catgctgcaa atcgtggtat cgtgattgaa aatcctaact tcactgttga tatggaaaaa
    81121 cttttagaaa ctaaatctaa agttgttaat actcttgttg gtggtgttgc aggacttctt
    81181 cgtagctaca gagttactgt tcataaagga attggtacaa tcactaaaga caagaacgtc
    81241 ttggtaaatg gttctgaatt gcttgaaacc aagaaaatca ttcttgctgg tggttcaaaa
    81301 gtcagcaaga tcaacgtccc tggtatggaa tctccacttg tcatgactag tgatgacatt
    81361 cttgaaatga acgaagtgcc agaaagcctt gttatcatcg gtggtggagt tgtcggtatc
    81421 gaactcggtc aggccttcat gacatttggt tcaaaagtga ctgttatcga aatgatggac
    81481 cgtatagttc cagttatgga tgcggaagtt tctaagaacc ttcgcttgat ccttgagcgt
    81541 aaaggaatga ccatcttgac tggtactaaa ctgcaagaaa tcattgagga aaatggtcaa
    81601 cttcgtatca aggttgaagg aaaagacgat atcatcgcaa ccaaagctct tctttcaatt
    81661 ggtcgtatgc cagaccttga aggtattgga gaggttgagt ttgaattgga tcgtggttgt
    81721 atcaaggtca acgaatacat ggaaacttca gttccaggca tttatgcacc aggtgacatc
    81781 aacggtacta agatgttggc tcacgcagct ttccgcatgg gtgaagtttc cgctgaaaat
    81841 gcccttaaag gaaatcatgc agttgccaaa ttgaatttga ctcctgcagc catctacact
    81901 ctccctgaag tagcagcagt aggtttgaca gaagaacaag cccgtgagaa atacgatgtt
    81961 gccatcggta agtttaactt tgctgctaac ggtcgtgcta ttgcatctga cgctgctcaa
    82021 ggtttcgtaa aagttatcgc tgataagaaa tacggagaaa tccttggtgt acacattatt
    82081 ggtcctgcag ccgcagaatt aataaacgaa gcatcaagca tcatcgaaat ggaaatcact
    82141 gttgaggaaa tgctgaagac catccacggg cacccaactt actctgaagt gatgtacgaa
    82201 gcgtttgcag atgttctagg aatggccatc cattcaccta agaaaaaata aaacgaaaat
    82261 agattagact ggaaggttat ttccagtttc tatcatatat catataaagt aaagggatat
    82321 catgaaatac attttttcag aagaagaatt ggccgaaatc aatcgcatca aggatactaa
    82381 gtttggaact tgggactgga actatggtaa atcacctgaa tttaacgtcc gtcgtggaac
    82441 caaattcact agtggtaagg ttgaagtctt tgctaacgtt actgaatcaa aaatccaaga
    82501 catcaagatt tatggtgact tctttggtat tgaagacgtt gctgcagtag aagatgtcct
    82561 tcgtggggtg aaatacgaac gcgaagatgt tcttaaggcg ctaaaaacca ttgatatcac
    82621 acgctacttc gctggtatta gccgtgaaga aatcgctgaa gcggtagttg gataaatcga
    82681 gtaggggata atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt
    82741 tcaactaact tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg
    82801 tttttccagg actggttttg atatagcacg tttaagtacc tacttctgag ctactaattg
    82861 ataatggtcg tcccagccag ataccttatc tgctatccat ttaggaactc ctaacttaag
    82921 caatccccat aatcgtctcg atttcttctt ccattgcttc cagataatca ctcgtaggcg
    82981 agtacgcaag cgctcatcta tgctagtgac tatacttttc atattcccca atgagaaata
    83041 gtttatccag cctcgaatgg acaaattcag ttgctcaata cgtcttgtta agtctatact
    83101 ccatttcatc tgtgttagtt tcttcaattt aagcttaaat ctccgaacac tatcttgatg
    83161 tggacgactt ttccaaccat ctgatgattt ccagaacccg aaacctagat atttcaactc
    83221 tcttggtctg gtaatcttag tcttggttat gtttactttc aaacctagcc gtttctcaat
    83281 aaaataactg actgaataca tcacacgctt agcggcagcc tcgcttccga ctgtaatcac
    83341 acaatcatct gcgtagcgca caaatcgaag tcccctcttt tctaattcct tgtccaattc
    83401 attaagcatg atattggata agagaggaga taaatttcct ccctgtggcg tgccaactag
    83461 cgttttatga cgctgaccat taatgataac acctgaatga agatacttac gaatcaagga
    83521 ttccgtatct ccgtcttcga taatgttatg tactaaggac atcaatctat cttgaggaac
    83581 cgtatcgaaa aatttctcta ggtctatatc cactatccac tcatagccgt catttaagta
    83641 ctctaagaac ttcatgatgg ctttttcaca tgacctattt ggtctgaaac cataactcgt
    83701 atctgagaaa tggggttcac aaatggggct catgacttgg acaatggcct gttgaatcat
    83761 tctatccata actgttggaa ttcctagttg acggatgcct ccgtttggtt taggaatctc
    83821 aactctaaga actggttgag gcttatattt tctctgtttt atcagttcct tagtcaagcg
    83881 ccagttttgt ctgagataat tatccatctc ttcgatagtc attccatcaa tcccagctga
    83941 gcctttattg gattttactt gattgtaggc ttcaagcata ttttcgcgtg ataatatctt
    84001 atctagcaat tttgacatgt gcgtattcct ttcttgtttt ggtgcctgag ggatatctta
    84061 tattggtgaa ccttcatcta gtcaatacgt gacagaggcc agttctataa gaccgcttgt
    84121 tttacagaca caattgaagt aggattactt caattagttg ttcacccctt cgctccactt
    84181 ccattacaga agtttcctca ctactatggg ttcggctgac ttctcatgat tcgttgttac
    84241 tacgctttca tcgctcatga gacctcacgg gataagtcgt acatctttcc tcgtttatac
    84301 aagatatgag gacgttaaaa ggttacagtg aaaataggaa atctgacgca gagtctttag
    84361 actctagaaa gatttatctt tttcacacaa accttagtcc gaattcaatt actctcgtga
    84421 tttacgcata taggttacga ctaccttttt ggactttaga gtttgaggcc ccttatccgc
    84481 tatatacgcc ttactatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
    84541 tccctgctac ctcacgatag tcaggcttgg gaatcgctat tgggttcacc ggtagcgggt
    84601 gcccacggag gacttacacc tcagatgcac gacatgcccg tcgtacttca aaaagaagtt
    84661 ggccaactaa ccaacttctt tttttgatat ttatttacat aatttaaaat acgtaaaatt
    84721 ataaactatc cagagcattc ttttgttcat cactaacaat atgggtatag aggtcagtga
    84781 cttgtgtgct agcatgccct agttggtgac tgactaaaac ttgtgattta gtcgcatcat
    84841 agagcctagt tgctagcgta tggcgcagtt tatggggggt tacacgtact ttaaaatcct
    84901 ctgagtattt agcaaccatt ttctcaacgc tagaagcatc gatacgatta ggaacacctc
    84961 tgtagagagt taaaaaaagg gctgtatctg ttttttccgt tttatagcgt tgattccgaa
    85021 tggccagata attctctaaa taaggtttag caaaagcagc gacattgact aagtcacgtt
    85081 tgccaccttt tcgagtaaca tcaataacca tcatttttag attgagatct cttagatcta
    85141 gattaacagc ttcagataag cgaacaccag atgccaagag aagggcaata atggctaaat
    85201 ctcgttcttt atttttgttg aatgatgaga gagctcgatt tgaaagctgt tgtgggtgct
    85261 cttgatcgat ataagttaga aaaccttctg tttcatcacc tagaaagagt ttttgcttga
    85321 tattttcagc tctggcagca agggtttctt tctttttctt ggttgaaact tttttcatta
    85381 cattacgata gaaataaggt tccccctgat cgttttcaac ctcctcggtt agatacttgt
    85441 aaagactaga aagtgctgat aaggttcgat tgatagttgt ctgtgaaaca ccttgttttg
    85501 ttgtattagc attcagcaag ggacgttcac gtagataaag gataaaggat tccatgtctt
    85561 tcttagacat attttccaaa actgataaag gaatatcgga tattttatca gcgtttgaaa
    85621 taccagactc caaaacccag ctgaaaaatc ggtcatattc cttaaggtat tcgtacaggg
    85681 ttgtaaaact gtagggcaca gccagcttag attggtagta ttccagaaca taccagggca
    85741 tgagttgttt tagtttgtcg attcgttcca gtaaaatctc acgtttcatg tattttctcc
    85801 ataagtaagt atactagtag tatagcatag acttgtatat ttttcaagaa aattatagtt
    85861 tttcagaaag atgttatagg agtttttcaa agtgataaaa agacttagac ctacaaacaa
    85921 aacagaataa ggaaaataat aaaaatctca cccactaaac ttctgttaat actacataac
    85981 tgaagagcta tataaggagc tatgagatac aaaacacatt gtataataga ttgaaactag
    86041 aatagtacat ctggacttct aaaacattgc tagaaattga tttgattgtc ctgattgttt
    86101 tatcatattt ctatttcatt tcactatata attgctattg ttttcttttt catgatttta
    86161 atcttactgt acagatttga tacagtaaac tcctttctag ctttatactt tatcatttct
    86221 aacttaatta tagtcttatt tttaataaag ttcaattatt tatatgtaaa attcctcatc
    86281 agtaaaaaat aaccgatctc atttctgaga atcggttttc taaataaatc aagctgatta
    86341 tttacatagc ataaattatg taaataatca tactacaaca acaaatcttt gacttttcca
    86401 atttcacttt ttggaataac caggtgaatc atatcaccca gatacattct ggttgagccg
    86461 ttaactgttt ggctcttgcc attatggact tgagttgtga tgaggacgtt gtgtggtaag
    86521 ttgagttcat gaacttgttt cccagcaatt ttatcagaaa ctggtatttc gataagtgta
    86581 acttctcctt cgctagatac ttcttctgga agcatttttt ccagcatggc ttcatagact
    86641 ggcgtacctt tgagcaaatc catgataata taagaaacaa gagtgacaag accaagtggc
    86701 atgaggttgc gaatatctcc taccatctca gttacgagga tcatagcggt taagggagct
    86761 tttgatatgg ctccaaaata gccactcatt cctagaatga caaatatagg gaattgctct
    86821 tgactgacaa gtccaagatt gacacagata acaccaacta aggcaccaag caaagaacca
    86881 agagctaaaa tggggaggaa aattcctcct ggcagtccac ttccatagct aatcatactc
    86941 caaataaagc ggatcaaaaa gtaagctaat aaaacttgga aactaaaatt ttgttcagtt
    87001 aaagaaagga caagctgatt tccgccacca aggatttgag gtaagaagat tccgactggt
    87061 atgataagga taaaagccaa gatgggataa taagctctat ccaaatggat tttttgacca
    87121 atcaagtcat aaactcttcc aacgtttaat acagctttct catagagaaa gcctgaaaat
    87181 ccaaggaaaa ttcccatgac gagatatatc caatactgat ctagggtcat gggaggaatg
    87241 ttatctggca tatccaatac tggtgtcaaa ccgaacatga gtagagacac aaagtttgct
    87301 acgatgctgg ctgctagagt tgagacccag aaaaagcgcg aaaaatggtg atagacttct
    87361 tctacaacaa agagaagtgc tgcaatagga gcattaaagg ctgcggctaa acctgctgca
    87421 gctccactgg caatcaagga gcgttcctct actggactgg atttgagcca cttggcaatt
    87481 cctttaccac caactgctcc aagttgaata ctgggtccct ctcgacccag catgagtcca
    87541 ctggcaatag caagaatacc tagcacatat tttttccaaa gaatgcccca ccagttgagg
    87601 gacatgaggc ctttcagttc ggcttcgact tgaggaattc ctgagccttt aatatctttt
    87661 tctgaccgtg ttagtttggc actgagccaa cagatgagta tataaaacaa aaccagtaca
    87721 aaaagattgc gcactaagta cccttgatct tgataaactc cttgtatcag gtggaagccc
    87781 ttttcaatta agaaacgaaa ggatccgacg ataattccaa cgatgaggcc gacaatgatt
    87841 cctcgaccaa cttgggatag tatagtgctg gatgcaaagg cgaattcttt cttagaacgg
    87901 actatttccg actgttcctc catggtattt cctttcaatt aactttcttt tttacctaaa
    87961 accagtgatt taacgggttc aaagctggtt cggtgaattg gggtaactcc tagttttgtg
    88021 aggccttcca gatgtttagc tgtgccatat cctgcattag tagcgaaatc atagccaggg
    88081 aactgctgat cgtattcctt catcaattca tcacgtgtta ccttggctac tatagatgct
    88141 gctgcgatag agagggagtt ggcatctcct ttgataatgg aggtttgtga aatgggcaag
    88201 tccagtttca tggcatcaat caaaaggtgc tctggttgag ggctgagctg ggagattgct
    88261 tcttgcatgg ctagtttggt tgcttcatag atgttgactt ggtcgatgac ctgattatct
    88321 atgataccaa ttccaatcga caaggcttgg tcttgaacgg cttggaaaat ctccagatgt
    88381 ttctttttag gaattttctt gctgtcgttg agacctttaa tcttacaatt tttaggtaaa
    88441 ataacggccg cagcgactac aggaccagca agaggaccac gaccaacctc atcaatacct
    88501 gcaattaagg tcaatccttg cttataaagt tctttttcat aagaaagcat ggattccaag
    88561 cgcaaatttt catctaattc agcttgaatg gctcttttac gcttgctgat ttccttttga
    88621 actcctgagc gattatcctt ttcaagctct aaaaaaatag ggctttctaa ctccttgact
    88681 gtcacaagga gttctttgat ttctttaatc gttgccatcg aggtcttcca atgtatctaa
    88741 ggtatagtta ccgagtttgc catcacggac ttccttcacg aagagactgt aaaaacggtc
    88801 atagtcatca cggaaaccga gggcacaggt catatccata ataatcacag gcgcttcttc
    88861 ttcaattttc atttgtttga agcgttcagc cagcttttct ggataatgtt ctttgaaata
    88921 attgatacca aaaatggtaa cctcatccat aggaagcaac tgatccttga tagctccagt
    88981 caatgccaac ttaagtgcaa cagtttcatc ctcaaactta ggccagagaa tccccggtgt
    89041 atccaagatt tccagatctt tattggtttt aagccattgt tgaccttttg tgacccctgg
    89101 cttgtttcca acaacagcaa tctttttacc agccaaacgg ttcatcagag ttgatttacc
    89161 agcgtttgga atcccaataa tcatggtacg caaggtttca atctgaatcc cacgttcttt
    89221 ctggcgagca atcttatcag ccatgagctt cttggccgca tctgttacaa cttttacagt
    89281 cacttgctct ttggagttga tagctagcgt ctggattcct tgtgattcaa aatactgacg
    89341 ccattccttg gtcattgctg gatcagccaa gtcggccttg tttaaaatca agagttttgg
    89401 tttatcacca acaatcttgg tcaacatagg attttgacta gatagaggca agcgtgcatc
    89461 tactaaaatc gtcacaaaat caacaaattt taaattttcc tgcacctgtc gacgcgcttt
    89521 agacatgtga ccaggaaacc attgaatagt agccattgag ttttttcctt tcgtagcaag
    89581 gatttagatc ccctatttta ttttactatt gtttgaacat agagagtttt caaatgaatg
    89641 atgtccaaac agttcttgtt ttatgacata gaaatctact ttatattata tcatgccttc
    89701 tttattttgt ccgatgatag ccttttaccc tatcttttac cctatataga aaaaagccat
    89761 caaatgatga cttttcagag ggagcaaaaa actgttccct ttatatttta aagatttaaa
    89821 tgtctttttt gaacaatgga ttaaagaaac cgtctgtgtt tttaagaagg gctttaaaga
    89881 tcttggattt caagtccact gtatttttga aatgattttt aatttttgga tctgacatac
    89941 catcaagatc tttttgaact gcttcagcaa ataaagtgcg caactcatca tagttgctaa
    90001 tatggactcc atcaatatcg atagcctcaa aacctttctt agctttagca agaacttctt
    90061 cgtaccaatg tctcttccac tcttcaaggg tactaaagtt tccttttgat actttagtaa
    90121 ttattagctt atcgcttagt aaaccatggt tgtttttatc cgcttctgct ttgtatttat
    90181 ttgacacata actgataaat ccattttcat aaccatagta accccacata cggaaagcat
    90241 tgtgcttaaa cgataatgaa ccaggtgcac catcactcgt atttccaccg taaattcctg
    90301 ccatcatatt gacatttacg taagctgatt ttggtgtaaa atcctctggt ctataacgtc
    90361 cgttacctgg attaccatga atggtcatga aattattatt tactaagtca tcaatggaat
    90421 tcagtggtgt tgttctctca gcgtctgtca agtcacgcac tttgtcccat tggtgaggag
    90481 cacttagttt atttctatcc attggtcgac gtatttcacg gtcaattttc ttgaaccatt
    90541 tgctattgtc accatttaat tttggaatta cagcatctgc ttcaacataa tccaacatca
    90601 ttaacgcttc attgtagttc ttcatgtagc gatcgatgtc ttcacgagtt tgtaacttat
    90661 caggattata attgtaccat tggttaccat cattttcacg gtgataagcc atgttaaggc
    90721 ctaaagcacc atattctccg tttggatttg ataccgatgg cgtttgcaac ataccttgag
    90781 caaaggcttc taaatccgta ccttggcgat gccaatgacc accatagtaa accatacgat
    90841 cattaacgtg agtagtttca tgtgtaaatg cggatgttcc aaaatcacta attaaatctg
    90901 tcataacgaa ataaactgaa tccatcggtt gcggtgctgc aaaaatatat gcatatgctc
    90961 cgtatccata ttggtaagga tgatacttcc caatacgacc aaagaattcc ctgactggat
    91021 tatagtctgg ttttccattt ctatgtccga atctatcagg ccagccacct ggagcgttat
    91081 gattatccca tacaggagtt ggaactacat tttgactctt aagaagttta tcgcggacat
    91141 tatcagtagc aagacgtgac caaaaatcta agtaattaac ttgctctttg gcacgtagat
    91201 taatctcttt tttaaaggct tcacgttctt cttcagtatt tttgttgtat ttttcaaacg
    91261 aactaaatga gatagtatta tacgttgaaa tcataaataa atgtgcattt ttcaagttaa
    91321 gaagaggtaa aatcatacgc ccatgctgtc cattattaat tccttcgtat agacgatatt
    91381 ttttgttagc aaatgcaggg ttcgttgatg gttgttcaac tacatacgca ttcttttcaa
    91441 tagctttctt aaaccagtca tttatatctg tatggttagt caatagcttc atattgtaat
    91501 gtaagaatcc atttaattca tttattccga ttgttccacc tatagtttca cgataagctt
    91561 ctaaagttct atcaccttta acatttcttt cacttgaacc aattttgatt aagaaatcta
    91621 agatattaac attcttacca taaaaatcag gtttaaacat cataatatct ttaattgata
    91681 acttatcgta tttaaaacca taatattgat ttaagtaggc aagtcccatc atgattttag
    91741 ctttgttgtc ttcaactttc ttcagtaaag cacgctcgac tgcttccccc catttaactg
    91801 atgatcttca ttttctaaaa tctgactaac aagtttttct aagtttcctt ttagttctgc
    91861 gaaactttct tctaagtaca agcctttaat atactccgtc ttcttctcag gagtatatta
    91921 aaggcttctc acgtttatcc atcaaagcac gaacttcatc tgaaagtaag gtaacactag
    91981 ctaacttctc tttaataccg cttgctaact ggttacgatt cttcataacc atatttggag
    92041 tatagacaat gttttgacct gctacatcat actcttttac ttgatctact ttagagtcag
    92101 ttttagcagt tacagttaac tcttcctttg taccatcagc atagtgaacc ataatcttat
    92161 caatatctga caaatcagtt acaaactgcc ctgctttcat acctgttaca gacagaacgg
    92221 ttttcttaac aagattggac tcatctgtta acttattccc ttggtttacg atccactctt
    92281 tattatagaa cggttgaagt ttttcaatat tgcgataggc ttgttcacgt tcagctttgt
    92341 aatcttgcgt tgtcttatac tcattatcac gagttgtcag gttgttgagt gtgtttacaa
    92401 gtggatccgt gatttcatac ttatcagcag tgatattgaa ggtggcaata cgtttatcag
    92461 cttcagcttg gtctacaccc tgaatttgtt ttgaacgttt atatgaaaca ttgcctgacg
    92521 caacatctct cacatataca ttgttcttga agtaatggaa tccaaagtct gggtcgcccg
    92581 aatccactga accagaaccg tacatgattt caccattgtt tactttcatc atgctgacgt
    92641 tgttttcaac ccatccccaa ttgtagttat cgtgaataac accaccactt tgaccatgat
    92701 ttttaagtgt catagtacct ttaacaacag atttcgttaa gcgacctcgt tgttttacat
    92761 ccatagggtt tacaccatgg tcaattttag caattagccc accgacctta gagttgttgg
    92821 ctttgatatc agcatcaata tatgagctat cgacattact tctccaactt tcactaacaa
    92881 gtccaccaga ccaccagcct ttatctccaa gactgttaat cttaccaata aatgctacat
    92941 tgcgcatatt agcttcatct aacttattaa cagcaccggt tacatcgtta tttcctgtta
    93001 ctgaacctac tactttgata ttttcaagtg tagagttctt aaacatatta ccgatagggg
    93061 caactttatc agcccaaggc atgttgatat ttacattacc caagttaaag tttttgagtg
    93121 tagcaccttc agcttcatta aacaaaggtc tttctaagtt atgaatcgtg tattgatgat
    93181 tctctacact tgataaagta cctctaaact taaccataac ataagcttta cctgctggct
    93241 taacgttaac tgcattcaaa tctgcaccaa gtttaaactc accggtagga tttgcttgca
    93301 tatcttttgc taaatcatgg aagttgtaat aaaccttatc ctcggtagcc ctcggttttt
    93361 caaaataata agtgtaagtg tctcttaact taccgtcttt gtcacgttga actaagtcag
    93421 gtgcttttgc tgttaccttg taaagttgct taccttcctc aatgacctct tcaatcttat
    93481 caattgctaa acgggtcact ttgttttctc tggaggttac ttttaagtaa tagttggtaa
    93541 catcacttgg aagagaggtt aagtgattac tatcactttc gacaccgctt tcgttcactt
    93601 gtacgagact tgtgtttgca atatctttca actcaacttt ctttaaatct aaacgtaaag
    93661 gtctatcttc caaagtcgat acttctgcac ccttacctac atcataagtc atagtagttg
    93721 aaatcgtata atctttgtaa taatccaagt tctctaagac ttgagataag ttatcggttt
    93781 ttaaatcaac cgttggtttt tcttttgtac cttttacaag aatttcaggc ttcatttctt
    93841 tcaaaattgt tactgtttca actggttcac taattttttt gccatgtaac tcttcatagc
    93901 tagtaacaat ttgacgttcg ccatcctcac caatttgttt aacagaatta tcgcctataa
    93961 atttggtagg atcagattct tctatagtgg ttttaggaat agtctctgtc cgaatatcgg
    94021 tatgtaaaga aggtgactct tctctttctg atgcaacttc tgaaactgta gatatcggct
    94081 cagtatactc tggaatgttg ctaacgggtg gctcaatcaa gtttccattt tcatctactc
    94141 ctgctgtacc tactggctca gtatattctg gtttctcagt tttaggtgct tcgtcaggaa
    94201 ccatacctac aggttgagtg tactctggtt tttcgctaac aggtggttca atcaagtttc
    94261 cattttcatc cacttctgtt gtacctactg gctcagtgta tgctagtttc tcatgaactt
    94321 caggctcaac aaggtttgca cctattggtt gcgtatagtc aggcttctca tgaatttctg
    94381 gttccccttt ttcagtcaca acttttggtt gctcaactgg cgaaacagtt gatgctggag
    94441 aaactgacga aacagttcta tcatcaagct ccaagtaacc aacatatctg taactggaaa
    94501 tttgcaacac accatcacgt ccagactcat ggatgttagc attcaaatta agtgctgaag
    94561 cagttgatag tgtaactaaa cctgtcgccc ctacaatcaa aaatgtagct atttttttcc
    94621 tctttttatc ttttgtgata atcacaataa gactcccgat agctaacaaa cccaatgcag
    94681 tcataataga ttgagaactt cctgtgtttg gtaatgcgtc tttttcataa accaaagcat
    94741 atgactcttt tgatttatca ggtctacctg atttcagttg agcacgctca ttttgtgtta
    94801 aattactata atctaagtaa tgataaggcg atgcaccaac aactgacggt gcgaataaaa
    94861 gactccccaa gaataccgaa ccaacaatac cctttatttt ccgaatggaa aatttatctt
    94921 ttttaataat gacaattcta attctctaca ttcacttttt atttcctaat agtaaacact
    94981 attttttatt ctcaaaaatt gaacttctaa aatcatcggt ttggtcaaga taagctttaa
    95041 agattgcttt cttgagcttg tggacttcac tatctatgtc tggattgtag ttattccaat
    95101 ggtagtaatt gtgttctgca tccttacgaa cagcaacgtc cattaatttc tgtaattcat
    95161 ctacactgct tgtagttttc ttggcaaatg tttgccaagg ctgtgttgta tcattaaaag
    95221 taactttatt cagtctatca aattgagcta cacgttcatt atacatagct ttcttgaatt
    95281 ctgtccaagt ttcatattga ccgttaaata ctttttgaag aacaagttca tctgtcacca
    95341 atccgcgttc tttaccataa atagttatct ttttaccatt ttgtttggca acttcttcgt
    95401 attggttgga aatatatggt accataccat ctttaaagcc tttagcagct agtagttcat
    95461 aggctatacg acgtcccatc aggtcacctg gtgttcctat atcactactt aatgctgcat
    95521 aaattggtgc aaataactta atagtgaagt agccatttct ttcgtattct ttagacttgt
    95581 attcacgagc tgaaaggatg ttattatcaa tcaaattctc aaagcttgtc agttttttgg
    95641 catcttcttc tgtcagattt tgtactacgt tagtagcgta aacctcattt ccatcttcac
    95701 gatctttcac gtatttattc tcgatttttc tcagggccgt cattttttct gttgcagata
    95761 gttgactgat tattgatttt ccttcaagat attctaacat ataaataaca tcaaacatat
    95821 tgtggacata ttgcttcaaa tcatctgcat tattaaatct cgtggttgga tcaagtactt
    95881 gtaatcgttg tccttctgta ctatccgatt ttgaatgttt taagatcgag ttgatggtga
    95941 tggttgcgtc atttggatgg tctggcgctt gtagtaatcc tttagcaaag aactctggtc
    96001 ccagtccact tcttctgcca tatccgccta gataaatgtc ctggtctgaa tcgtgcgtca
    96061 tttcatgagt ataggtaatg gcaccatcct tatccaacat acgataaccc atataataaa
    96121 cagcatcccc tgtagcgtaa gcaccgtgtt cattatgacc aaccttattt ccaacaggtc
    96181 caaagaaatg ttgcattgca ggatttggat catcaaaagt tgctactttt ttagcctttc
    96241 cttcggtatg atcatcacca aatttataag catcataaag caagatattt cgataaagct
    96301 tttcacgctc tttttcatct agaatacgat accaataatc atagtgatct cgctgacgtt
    96361 tggctgtctc acgcgcgttt tcttcaacaa agctatttag atcaccactt gcttgatgtt
    96421 ctttattacg atatcgatca taagcaccaa aacctagact agatatggtt gaaatgacaa
    96481 atactgattt ttctggcaag gtaagtagag gtagtaccat gttacggtat ttccagctgt
    96541 cgctagtgat tcgatcatag acaccgatag agtacttgct accagctttt tcctgattag
    96601 cttttacttc tagaatatta gatttttctt caacgatata agccttggtc tgtgatttaa
    96661 accagtcatt gttagtttga gtaggtgcaa atgctttacg atagccttct aaagcactaa
    96721 acagatcttt tgtaccgtag ttattcgtca gcaaggcatt gtaagtaacc acattatttt
    96781 ttgccaagag attgttgtag ccagatttac ctagttcaat aatcgtatca agaggagagg
    96841 tatttccctt accaaagaaa tccatatgga acataagcaa atcttttgcg ctagccttat
    96901 caaatttgaa atcataccag cgttctagat aggttaatcc tagcatcaag gcttctttgt
    96961 ttcgcttgat tttatcaaca atgtaattgt caattatatc attatttcca gaaacagctg
    97021 catcagctga aagtaatttt ttaagagtct cagtcaagtg ctctttggtc ttagcgaatt
    97081 gctcatctag atagagttct gttaatttaa cattatcaga gattcctaac aaattcttaa
    97141 gagaagttgg atcatactga actgtattta aatcattttt aactctgtct attatagatg
    97201 tataatcttt taggaaagca tttggtgtgt atactagacc tgtagttcca atagtatact
    97261 cagccagatt tgcaaagtca ctatggtagg ttacgtttac tttctcagat gttccgtctt
    97321 tgtaatgtag tagtaagtga ttgatagagt tcttatttga agtgatatca gagactactt
    97381 cctcattttt catagctaca acagacaaca attctttttt aaacaggtta tgatcagtag
    97441 ataattgatt tccatatttc acaatggtat ctctattata gaaaggcaat aatttttcta
    97501 tatttttata tgcaatatct cttgccactt gataatgagt tgcctttgta taatctacat
    97561 cctgtttaac agaatttgtg aaatcttcta cggttatagt gtgtttttta gtaatctgct
    97621 ctttcttagc ttgaactgct gttttttcaa tctcagtacc acgttctaca gtggaatcaa
    97681 ttgacattac ctcatctcca actgcttgaa cattgactac tttattgtct ttattactgt
    97741 aaactgcttt tttcttcata ccattgaagt ggtaaccaga aatcgcattc ccatttgtaa
    97801 tattcatatc gcttaggaca ttttgtagaa tcccagaatt gtcctccgtg ctagagccat
    97861 ttgtccaaag ggaacctgca actccaccaa ctctagcaaa tggtttaaca ttatttattt
    97921 caccttcagc atagctattt tgtacagtcg cattattttc tacgatacct gcaattccac
    97981 caatggtttg atttgagtat tctgcattac ttgaaatggt tactgttgca atagaacgat
    98041 ctacactagc attcgtacca gttaattgac cgactagacc accaattgca tactgagagg
    98101 ttgtaacgaa ggtatttgtt attcttccag tgaagctact attacttatg gtagaattat
    98161 caactttttg gacaagtcct ccgataccta gctcaccagc aatgattcca tttgcgtgaa
    98221 cgttatctaa agttgaagaa tttgtggctt ccttagcaac tgatgcgaca tgattcttac
    98281 cagaaatatt gacatctttc aaggtgagat tctgaatagt agcattattt aatgtattaa
    98341 ataacggctt tttcaaatta tagatagcat aatgtttacc ttgatgacta ccaattaatg
    98401 ttccggtaaa tttacttgta acataacttt cttggttttc atttaactca aactcgcgag
    98461 cattcattgt tgcaccaagt gtgaatgttc cacttggtct actattcata tcagttatta
    98521 attttttaaa tgatgtgtag atagggctat cgttttgaac aagttttgga agataataag
    98581 taaaattgtc ttggtattga ttgtctacag attgcttcaa gtgttccaat ctagctgtaa
    98641 ttttatagac tgctttaccg tcttttgtag tgtcttcaat gtttgaaact gggagcagta
    98701 catctttaaa tttagctgac ttcactttga tgaaataagc agatttatta tctggtactt
    98761 tatctaagct tgtatgttgt tttgattgat tgccttcata actatagagt tccacatcag
    98821 aaacacttct tagttctatt gttttctctt gttcttctac ttttttatca ggttctactt
    98881 cagttttatg tttaatttct tcgctttcat ttgaattgga tgtttttgat tcagttgata
    98941 catcctctgg cgaatttcct tttggttggt ctggttctgt ttgtccgctc tctgttattg
    99001 gatgagcaga attttcaggt tttgttgaag tttcgtcttt tgactcatct ttttcaggtt
    99061 tatttgtttc ttcaactggt ggttttgaat cactaggatt actggacact tccccagtat
    99121 tttcgttaga tgtatctggt gatattttct ctgaattcgt tgttgattct tctgcaggtt
    99181 gaactggatt ttttgctcct tgatttgagg ttccttctgt agtgccttct gttggattta
    99241 ctggaacttc ttcagttttt tctggttctt gttctttcgg cttctcgact ggagttgcat
    99301 cttctccttg ttttccaaga ttctctccgt tttgagaaga atctacggtt ggaggtatag
    99361 agtgactttc cacttctgag ttcatatcac tagataatgt atcagcttta gttgcagcgg
    99421 actctgtagc tacagctcca acttgtccat ccctaaattc tggaacagtt tcatactgtc
    99481 cgttaatcac ttgtattttt gatggactct ctataaaatt cggtgcaatc gtataatcca
    99541 ccttttgttg atttttagaa gtatctactg atttttcttg attatttact ttagactcag
    99601 aagttatgtt tctctctttg atatatccaa tataagtgta gcctgaaatc tctttaggaa
    99661 gaggtaattt ttctcctgtg gtcaattcat agtcagtatt gtaattcagt aagagattat
    99721 tttctaaagc atgagccgat acaagaacac catttcctat ccctgcaacc aatactaaat
    99781 gtaatactgt tttattctta acttttttct tagaaacggc aaaaattaaa atccccagag
    99841 cagctaagct agcaccagca actaaggttt tcatatcatt cttgcttcca gtatttggca
    99901 attctcccag ttgattttga gaatttaatt tataaacaag ataataagtc tcatcatcat
    99961 tctccatgca tgtcggaata tcatagacaa gctgcttctt ttcatctgat gatagctctg
   100021 actctgtcac atatttatag tgaacacctt tagtctcttg agtctcttga gcctctacag
   100081 atgaactacc taatacagac ataaaaaata aacttgaaat cgttgcagat acaagtccta
   100141 ctgataattt tctaaatgaa aaacgctgct gtttttcacc aaaatacttt tccatgattc
   100201 ctccttgaaa tacaatttat agatgttaca aaaaccttta ttatattagt gtgttatcta
   100261 taaaaaatgc agtataattt aattatacta ttaatttaca aaaaaatctt aaaattgagt
   100321 tgcgctttca tactttgttt tacgtgtaaa atacgaatgc gcagggtttg aatttcttat
   100381 attctttttg gataaaatgt aacctaccat gaaatttcca cggcaggtgt tattcatatc
   100441 actaatcgtt ctaaaaatgg tttgatgcag ttgaggagaa tgccttctat ccagctttct
   100501 tgtgctgagg agagatgatc tgcttggagg ctttctttca gaaaatctcg aacttgttct
   100561 ggtgcgattt caaactcaaa agctttcatt ttatagaaaa agtcgataag atgatctgat
   100621 agatattcag ttgaaaatgg aacttctcca ctttttcgat attctaataa gagccgagcc
   100681 aatctggatt tttcttcagg aagctcacga aaatagggat tgaggagcca ggtctgcttc
   100741 tgctttcttt caattggatc ctgactggct attcgttggt ctttttccaa ctctttttgg
   100801 tattgtttgg ccttgatagc ccgttctgtt cgatttttac caaaaaaaat tttcgcccac
   100861 ttgcgttctt cttgagtcag agtctctgta aagccaaagt aatcttgata gacacgctct
   100921 gctgggccca tggctaggac tagattgtct gcatattgct tggcgatttt atccctcttc
   100981 ttgcgctctt tctctgcctg gatacggagt tcttgctcgt aatcaatttt ctccttgcct
   101041 agctttacaa gatagagttg gtcatccgat ttcccaagta aaaagggttt gatacacttt
   101101 tcaagaactt cctccatacg agccttcttc ttgggctctg ccttggtcca acttcctcct
   101161 tgaaagactt ctaggaagag ttggtagtct ctctcaggtg agaactgatt gccacgatta
   101221 ggtttaaaaa cacctttttc ccagagccac tttagaagcc gctcgtcaaa gtcactttta
   101281 ttgaccttga ttttttcctt tttctggact tttttggtca gattttcaac ctttctgagc
   101341 agtttttctt cctcttctag ttgctggtca aggggcaatc gatgaaaatg acgaacacag
   101401 tcgctaccaa tcggaaagag gcgttggcct gtgacaccat taaagagttc gtaggcgtac
   101461 ttgatggcat ttccacagac acaattacta cggccgattc cgttaaaaat caaggaaact
   101521 tcattccatt ccttggtagc ttgttcccaa gtatcagctt ttgaagcctg taaaaccgca
   101581 tcgtgcaggg attttctaac tggaagtgtc atgaggtctc ctttctagat tatactttta
   101641 caacttgaac ctcatcttta ccgagtaaaa tcaagtattt ttcaatattt tcaatcgaat
   101701 aggctcgtga taaagcctct ccgtataggg ctaattgacc acgatagcga tctatgagtt
   101761 gacttggttc atcatagcgg tctgtcttat agtcgaacag aacgattctg ccctcgtaaa
   101821 gcagatagcc atcaaggata ccacgaacaa cgaaatcttc ctggctcttt tggtctcgtt
   101881 tgagcatgga gaaaggttgc tcgcgataga gatggtcggt attagcaaga atttcctgac
   101941 cgagtgctgt gtcaaagaat gcaagaattt tagcaagatt gatcttgtct ctgacagctg
   102001 ggctggtttg aacttgtttg agagtttctg tcaggctagc aagcgtcggt tgttgactga
   102061 ggtcaattct ctgcatgagt tcgtgggtag cactaccaat ctcagctcct gttacctttt
   102121 ctttgcttga aaaatctggt aaatcaaagc taattttctt gtctactgac tgaccttgac
   102181 ctgcaatctc gacaccttcc atatccataa caggttcgta aaatttcttg atttgacttg
   102241 gggtttgaac actaggaagt tcaatagctg cacggtgaag agtattataa acttccactt
   102301 ctttcagcat ttccagagct tctttaatag tttcagactg gcgattgtct gcttgggagc
   102361 tatcttggag aggactcttg gttttcaact ctccgatagc ttctctggtc aactgatctt
   102421 cgccaacaaa acgataacta aagttgagct tgtccttagt aaacacttta ctgacagccc
   102481 aaagccaatc ttggaaattc cttgcttgca gtctagtagt gctatttagt tttccatttt
   102541 tagctgctgg gtattccttg gcttccaact tttcacgaga acccttaccg acaagataga
   102601 gctttttctc agccctcgtc atggcaacat acagcagacg catttgctca gaatagcttg
   102661 ctagctgtaa ttcttcttcg ttctgcctat aggtcagact aggaatggag agtttgatgg
   102721 ttttaggata gtggtcttct actgcccctg tctccatctt ggcaatatat ttgacaccaa
   102781 gaccattttg acgactgaga atgacttctg acatagagtc ttgcttgttg aaatcttgat
   102841 ccatattgag gataaagaca taaggaaact ccagcccttt actcttgtgg atggtcatga
   102901 gctctactgc atcttttggc ggtgcgacgg ccacgcttgc caaatcgtgc tgggcttcta
   102961 aaacttggtc aatcatacca ataaaacgcg acaaaccttt gaaattgctc ttttcaaatt
   103021 gatcagcacg cagtgctaag gcatagagat tggcctgcct agcaggacca ttcggcaaag
   103081 ccccaacata gtcataataa aaacggtcgt tgtaaatctt ccaaatcaag tcatagagag
   103141 agtgggtttt ggcatacaag cgccaagaag ctaggatatc catgaattgc tttagtttct
   103201 cagctagagc tgtgtgaatt aagccttttt gactacttgc cattttttgt gcattgacca
   103261 gtttctcata gagattttcg tggactttat cctctgcttt ctgaagggac aaacgtgcta
   103321 gctcatcctc atcgaaacca aacattggag acttcataag ggcaaccaag gcgtagtctt
   103381 gcaggggatt gtgaatgaca cgaagggtgt ctagcatgac ttgcacttct agggattgga
   103441 gataattgtt ttgctctccg tcagttttga caggaattcc gtactcagac agggcgagga
   103501 gaatctggtc attacgactg cggctggagg tcagaagggc aatttcttta aaggcaacac
   103561 ctttttcttg atgaagtttc agaatctcct tgataactaa gcgcatttcg cctgttagtt
   103621 tcgtttctgc ctgcccctct tcttcctcac ctgtgtcgtc cttgtcatag aggagaaatt
   103681 ctaccttgtt gtctggattg ggagtcagtt tggtattggc aaaaacaagc tggtgcatgt
   103741 tatcatagtt gatttcgccg acctcttgat ccataagacc ttcaaaaaca tcattggttg
   103801 ctgatagcac ttctgaacta ctacggaaat tttctttaag caaaatcagc ttgccttcgt
   103861 gtggattttt cgcatagcgt tgaaattttt cattgaaaat ctgcgggtct gcctgacgga
   103921 aacgatagat ggactgcttg atatctccca ccataaagcg attgtgccca ttggacaaca
   103981 attccagcat ccgttcttga atatggttgg tatcctgata ctcatcgacc atgacttcgt
   104041 ggaaacgctc ctgataagct tcacggactt gcgggaattt ctctaaaatc tcaatggtgt
   104101 aatggctgat atcagcgaat tcaaaggcat tttcctgacg tttacgctga cgataagcct
   104161 ccacaaaatc gctcataaag gtttggaagg ttttagctag tttccaagtg tctccatgat
   104221 aacgttcttg atagtcgaga atggttatct ggtctgataa ttgtcctagt ttagcaaact
   104281 gggtctttct ctcttcgttg taggcatcag ccaggggctt caaatcagcc ttacgactgg
   104341 cattagtaag agctcgaccg tttttctcct tagagatggc gacaacacgc gcaagcactg
   104401 cctgataagc ctgactatcg gactcctgat ttagggagcc aatttcatcc agaattaact
   104461 gaacattttc taaataggca gcctttgcaa actccttggc atcgttatcc agatggtaac
   104521 ggaaaaagct ttccaaatcc caaagggctt gtttgatttg ctcagtcagt ttttcttttt
   104581 cactggtaaa atcagctttc tcaaagcctt tgaggaaaga ttcactcagc cacttttgag
   104641 gattactggt ggattggagg aagtcataga ttttatagac ctgctggcgc agaccccgtt
   104701 cgtccttgcc atgcccagca aagtttttca gcaaatgact aaaggtctct ttctgtttac
   104761 cttggtaatg cgcttcaaag acctcatgaa agacttcgtt ttcgagaaga agttgctcgc
   104821 tttggttttg taaaatacgg aaattaggtg caatatcaag cagataacca tgtttgccaa
   104881 ggaatttttg tgtgaaagaa tccatggttc cgatggcagc gttgggtagg tctgccaact
   104941 ggcgacccaa gtgttgtttg aggtcgacat catctgtttc ttggattttc ttgctgattt
   105001 ttttctctaa acgttcttta agttcagttg cagccttgac ggtaaaggtt gagataaaga
   105061 gttgagaaat ttcgacacca cgcgccaatt ggtccagaat gcgctctgcc atgacaaagg
   105121 tctttccaga accagccgat gctgagacca ggatattctg accagaagtg tagatagctt
   105181 cgatttgctc ggcagttttc ttctgttcct tgctcgaatt tgcttctgct tcttgcagtt
   105241 tttgaatctc ctcctcactt aaaaagggaa taagcttcat cgattcaact cctctcttat
   105301 tttttcaagc caagcttgct tgagtttttc tccgaccaga cgcttgccat cagctaggtc
   105361 caacttttct aggaaacggg cttggcccag atggtaattg gcttcaaagc ctgtaatagc
   105421 ctgatgttgc tggacgtatg gggcaatgct tctgccattt tcagtataag gattgatggc
   105481 gaaccggcct gctaaaatct tctcagcagc tttcttgtaa agataggcat tgtagtccag
   105541 taggagctga aattcctcat ctgtcagttg attagccttg tttttgttat aaaattcgcc
   105601 taaataactg ctttcttttt ccaagaagag cccttggtat ttcatagatt tgctggcttc
   105661 taccactgct cctgccagac tttttaccgc tatcagagat tggacaggtt cagccatttc
   105721 caagtacatg gcgccgaaaa agttctgctc cccttctctt tttagggcag caagataggt
   105781 tggtaactga gaattgagcc cattaaagaa atgaggaaac tggaactgag tcagactgga
   105841 tttgtagtct actactccta tcgctccatt agctttcaaa cggtcaatcc ggtccacctt
   105901 gcctcgtaca aagacactgc gtccattgtc taattgaata aaggcttggt cttttccacc
   105961 aaaatttgct tcttctttga tggtttcgat ggctggattg tgtcggagaa tatgtccagt
   106021 tgtccgtgca acatcaagca aaacttcctt ggtaaactgg gcttccaaac tttcttgata
   106081 aatagcttca aattcgcgtt cttgactggt ttcttgaata gcttgttcta gacgttggtc
   106141 aaaggaatct tcattaggca actgcaaggc gcgttcaaag atacgatgca agaaattccc
   106201 gtgactacgg gcatcaggac gcaaacgtaa ttcctcctgc aagcctaaaa cgtagcgtag
   106261 gaaataactg tattcattgc gataaaactc tgtcaaaccc gacgtagaca ggtaaaactc
   106321 ctgtttggca ggatagagag cttgcaaggt gtccttggct aaggtcttgc tgcttggact
   106381 ggttgggatg gctggatttt ccagaccttg cagatctagt tttttaccta tgacacgcga
   106441 cagaaccttg acaaaagtca aatcttgctc agtatcgctc atctcaccct gctggtgata
   106501 ggcaaccaga ctagacaaaa gactgtgata ggaccccata tcctccttag acagtccttt
   106561 gtgattcatc ctcttctctc tccgcctaaa tccaaaatgg atcaactctt gaagataggc
   106621 agattcctta ctttcacttt cgttaaaaag gcttggagcc gacaagaaca actgcttacg
   106681 agcagaattg accaaggaaa gcatagtgta gcgatttttc ttgagatttt cactgctggc
   106741 aatcagtaat tgaacgcctt cttcggtcgt ttggtttagg ttttgccttt cttcatctgt
   106801 cagaagactg gtgttttgag aaatttttgg taaattgtcc tgagttagtc caatagcata
   106861 gacaaagtca gcagtcaatg gtgcaatcaa atcgtaactc tgcaccagaa cagtgtccac
   106921 tgttgctgga atggtacggt attgggacaa actcattcca gaatggagca aggctaggaa
   106981 gtcttccaga ctaacctgtg aaccagcaaa aacagtcgca aattgttcta aaacatggca
   107041 gaaagccttc caaacttcgg cttgtctttc ctgttctaca gcttccaaag tggttgtcaa
   107101 atcttgtaac tgcttggtca cagctccttc ttttagaaag acactccatt tttgtaggag
   107161 gttttcagcc ttttgttttc ggctggcaaa gagggtttca agaggtgcta aaattctcag
   107221 gcggaggaca ttcaaacgct caagattaaa ttttccatgg tgggatttgg tgaagatttg
   107281 ctgaaaggct ggcaagccat tgataccaag atagcggata tattgctcaa aagcatcaat
   107341 atcagactga ctgaggtcag tatacaagtc agttctaaga agattaatca aatcctcctg
   107401 acgaaaacgg taacgtttta aagctaaaat agactcgaca aactgagtca agggatgatg
   107461 agccatggct tcgcttctac caagataaaa aggaatctga tactggtcaa aaatggtttt
   107521 gagagataac tggtaagaag ctacatcccc caagagaata cgaaaatgct tgtatctcag
   107581 gtctgagttc tcatgtaatt tctgacgaat actacgggct actagctcca actcctcctt
   107641 ttgcgtcaaa caagaccaga tttgtaaatt ttcacggtct ttctcatcga catccaaagc
   107701 gagttctgaa aagtcataag aagactccaa caaacgagag gccttgtcaa aactatccat
   107761 cttctcatga gtttgagaac agtcctgagc aggcgtttgg tatttagaag ccagatgatg
   107821 gagaaatttt acgctggctt ggtagagatt gccctcgcta aaaggactgg tataggcttt
   107881 cttactagca taagccccga taacaatctc aacacctttg ccgtgaagta agtccacaac
   107941 ccgctcttcc tcagcagaaa aacgagtaaa gccgtcaatg accaaggcga tttgattaaa
   108001 atcactactt accttgtcat tctcaatagc ctcaatcaaa tgggacaact gacttccctg
   108061 ggctaactga ccttgattaa gataggctgt tactttctca aaaatcaaga gtaaatccgc
   108121 cctcttatcc tcatctgtta aattctccaa gtccaaaaaa ctcatctgag atttggtcat
   108181 ctcatggtaa agctcaatta actgctggat caattgagga tcctgcttaa tagcgccata
   108241 aacacgcaag tccttgggat cgagttcggc aaggcatttg taaaaggcca acccaagacc
   108301 gatatcatca agagtagttt tagctggtaa atcattcaag accagatagc gagccatttg
   108361 agcaaagcgc gtgacggtaa tcgaaaaaga agcctgctgg gacaagtatt ccagcacggc
   108421 gcgttccttt tcaaaagaaa gagagttggg ggcaatgtag aagacccgct tgccagctgc
   108481 aactagctct tctgcctttc ttgttagaat ttctgtcaaa gaagtccgaa tatcagtata
   108541 aagtaatttc atctcagcct cgttggaatt tttcatcacc ctatattata ccatgattat
   108601 cctcgtaaat ctgttaaaat atttaggcca tcctttcttt tcttcatcat ctgctaaatc
   108661 ttaaatactt agctttactt gtattagata gaataagtct ggctactgaa aatcacataa
   108721 taaaaaagcc tcggtaacaa ggctttgagt tttatgattg tttcttatta ggtacggaat
   108781 acacttcaat gtgttgtccc agtatcttaa tgtcgactgg tagattgtct gatttatcac
   108841 catcaacatc ggactctaat tcgatatcag aagaagtttt aatattacgt gcctttatat
   108901 attcaatatt cttgatagaa tgattgaact atagcaaatt gaaactataa tagtacaccg
   108961 tggatgctaa aatatttcta gaaattaatt tgatttccct aatcaagctg ttcgtatctt
   109021 atttcaatct actatagtaa aatgaaccaa aaatagtaca taatgtggta taatcgtctt
   109081 atgggatatt caatagattt tcgtaaaaaa gttctctctt attgtgagcg aacaggtagt
   109141 ataacagaag catcacacgt tttccaaatc tcacgtaata ccatttatgg ctggttaaag
   109201 ctaaaagaga aaacaggaga gctaaaccac caagtaaaag gaacaaaacc aagaaaaatt
   109261 gatagagata gacttaaaaa ctatcttact gacaatccag acacttattt gactgaaata
   109321 gcttctgaat ttggctgtca tccaactacc atccactatg cgctcaaagt tatgggctac
   109381 actcgaaaaa aaagaaccac acctactatg aacaagaccc agaaaaagta gccttatttc
   109441 ttaagaattt taatagttta aagcacctag cacctgttta gattgacgaa acaggattcg
   109501 atacttattt ttatcgagaa tatggtcgct cattaaaaga tcagttaata agaggcaaag
   109561 tatctggaag aagatatcag aggatttctt tggttgcagg ggctaacaaa tggtgaatta
   109621 atcgttccaa tgacttacga agagacgatg acgagcgact tttttgaagc ttggtttcag
   109681 aattttctct taccaacatt aaccacacca tcggttatta tggtaaaatg aaataagaat
   109741 aggacaaatc gatcaggata gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt
   109801 actattctag tttcaatcca ctatattatg gataatgcaa gattccatag aatggggaag
   109861 ctagaactct tgtgtgaaga gtttgggcat aaacttttac ctcttcctcc ctactcacct
   109921 gagtacaatc ctattgagaa aacatgggct catatcaaaa agcacctcaa aaaggtatta
   109981 ccaagttgca atacctttta cgaggctctt ttgtcttgtt cttgtttcaa ttgactatat
   110041 aaattgtcta agcgaaacaa ccgataagaa ttggcacaaa agcgaccgta tttttgttac
   110101 caatacagga aaaccagttc atagttccat cttgagcaag tcgtctctcc agcgagcaaa
   110161 cgaacgcctt aaaaaaccaa ttcccaaaca tctgtcccct cacatcttca gacacaccac
   110221 tattagcatc ttatcagaaa ataaaattcc tttaaaaaca atcacggaca gggttggtca
   110281 ttccgactct gaagtcacta cttccatcta cacctacgtc acaaagaaca tgaaagatga
   110341 agcaatcaat gtactggata aagttatgaa aaagattttt taaaaagttt tgcccctttt
   110401 ttgtcctcta aatacaaaaa tagcccttcg gataaaatcc gaggggctag aaacgttgtt
   110461 aaatcaacga ccgaactttt gagtttcaag gttcgggata aaatagttca ctgaactatt
   110521 ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt caccaagttg
   110581 gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg aaagtgaacc
   110641 agtcttgatt tgtcctgcgt tagttgcaac tgcgatatca gcgattgttg aatcttcagt
   110701 ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca tttcgatagc
   110761 ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg agttagcagc
   110821 accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt cgtcaccaac
   110881 aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc agtcgttttc
   110941 atccatacca tcttcaatag tgatgattgg gtatttatta accaattctt caaggtagtc
   111001 gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag tgtagtcgta
   111061 aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga taaatacgtc
   111121 tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa caccatcttc
   111181 agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt ccaaaccacg
   111241 tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa gggcttcttt
   111301 aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg gagcgtcaga
   111361 gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag tgttgaatcc
   111421 accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag ctacagcgat
   111481 agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac cgtcaagtgc
   111541 gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga tagcttcagc
   111601 aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt aacgagattt
   111661 gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg atggaaccat
   111721 accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg ggttaccgcg
   111781 tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt actctcctta
   111841 tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc aagaaaaaac
   111901 gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt tgtctgtttt
   111961 attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat tacttgaaaa
   112021 agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg gtacttttga
   112081 ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt tagaaaaagg
   112141 ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg tgaagatttc
   112201 accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag aaactgatag
   112261 tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg ttattcatag
   112321 caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa aactttggga
   112381 agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta gctaaatctt
   112441 gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga gactggcatt
   112501 tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag cttggatatt
   112561 ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa taacaggaac
   112621 tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc tttgactatc
   112681 aagccttcct tctccaacaa caaccaagtc agcatctgaa actttcttat taaagttgat
   112741 taagtccaag caggtatcaa ttccagacac tatacttgcc tgagcaaagg cacacaaacc
   112801 accagcaagg cctccacctg atcctgctcc tttaatttct aatgttgcag gtgagaattt
   112861 ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat gtagaccttt
   112921 ttgattacca aaagtgtaag tcgcaccttg atgaccacat aagggactca cgacatctgc
   112981 tagaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg aaacagaagc
   113041 taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat cataaaattg
   113101 ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc caccaacacc
   113161 gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc caataccaca
   113221 agtttggatt tgaagtggat ttcgcttctc tagcggaatt tttccaagac caaccaagtc
   113281 agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt ctttttgtcc
   113341 aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc ggatagcatc
   113401 tacagtacct tctcccccat caccaacagg gcagaggaga tattctacat ctgctatcga
   113461 ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc tttccttaaa
   113521 cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacggtc aatcaaagga
   113581 agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt gagcacttct
   113641 ttggcacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt attaacccca
   113701 tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca tttttccaga
   113761 gtctcttttt t
//
LOCUS       DAVFJR010000003        90268 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVFJR010000003 DAVFJR010000000
VERSION     DAVFJR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 90268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.003"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(506..1696)
                     /locus_tag="VU722_000282"
     CDS             complement(506..1696)
                     /locus_tag="VU722_000282"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU1771338.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(1911..3254)
                     /locus_tag="VU722_000283"
     CDS             complement(1911..3254)
                     /locus_tag="VU722_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1771339.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(3394..4209)
                     /locus_tag="VU722_000284"
     CDS             complement(3394..4209)
                     /locus_tag="VU722_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU1771340.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPL
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(4261..6441)
                     /locus_tag="VU722_000285"
     CDS             complement(4261..6441)
                     /locus_tag="VU722_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU1771341.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPNQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(6727..7653)
                     /locus_tag="VU722_000286"
     CDS             complement(6727..7653)
                     /locus_tag="VU722_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1771342.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEEAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(7646..8338)
                     /gene="ftsE"
                     /locus_tag="VU722_000287"
     CDS             complement(7646..8338)
                     /gene="ftsE"
                     /locus_tag="VU722_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU1771343.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(8356..9451)
                     /gene="prfB"
                     /locus_tag="VU722_000288"
     CDS             complement(join(8356..9378,9380..9451))
                     /gene="prfB"
                     /locus_tag="VU722_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU1771344.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIVILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(9559..10215)
                     /locus_tag="VU722_000289"
     CDS             complement(9559..10215)
                     /locus_tag="VU722_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1771345.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(10523..11233)
                     /locus_tag="VU722_000290"
     CDS             complement(10523..11233)
                     /locus_tag="VU722_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771346.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(11233..11997)
                     /locus_tag="VU722_000291"
     CDS             complement(11233..11997)
                     /locus_tag="VU722_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771347.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(11997..12953)
                     /locus_tag="VU722_000292"
     CDS             complement(11997..12953)
                     /locus_tag="VU722_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU1771348.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILTVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVTS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(12957..13826)
                     /locus_tag="VU722_000293"
     CDS             complement(12957..13826)
                     /locus_tag="VU722_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU1771349.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGIVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(14094..15254)
                     /locus_tag="VU722_000294"
     CDS             complement(14094..15254)
                     /locus_tag="VU722_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1771350.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(15356..15604)
                     /locus_tag="VU722_000295"
     CDS             complement(15356..15604)
                     /locus_tag="VU722_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU1771351.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(15683..16273)
                     /gene="clpP"
                     /locus_tag="VU722_000296"
     CDS             complement(15683..16273)
                     /gene="clpP"
                     /locus_tag="VU722_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU1771352.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(16447..17076)
                     /gene="upp"
                     /locus_tag="VU722_000297"
     CDS             complement(16447..17076)
                     /gene="upp"
                     /locus_tag="VU722_000297"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU1771353.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(17165..17632)
                     /locus_tag="VU722_000298"
     CDS             complement(17165..17632)
                     /locus_tag="VU722_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU1771354.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(17651..18208)
                     /locus_tag="VU722_000299"
     CDS             complement(17651..18208)
                     /locus_tag="VU722_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU1771355.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            18333..19178
                     /locus_tag="VU722_000300"
     CDS             18333..19178
                     /locus_tag="VU722_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1771356.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            19237..20412
                     /locus_tag="VU722_000301"
     CDS             19237..20412
                     /locus_tag="VU722_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU1771357.1"
                     /translation="MKHFDTIVIGGGPAGMMSTISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTIIELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVNGGEVLSLDVLPQLSEKNLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            20432..20887
                     /locus_tag="VU722_000302"
     CDS             20432..20887
                     /locus_tag="VU722_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1771358.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDCRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            20996..22286
                     /locus_tag="VU722_000303"
                     /pseudo
     CDS             20996..22286
                     /locus_tag="VU722_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(22426..23175)
                     /locus_tag="VU722_000304"
     CDS             complement(22426..23175)
                     /locus_tag="VU722_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU1771359.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            23280..23501
                     /locus_tag="VU722_000305"
     CDS             23280..23501
                     /locus_tag="VU722_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU1771360.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            23498..24749
                     /locus_tag="VU722_000306"
                     /pseudo
     CDS             23498..24749
                     /locus_tag="VU722_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(24771..25715)
                     /gene="manA"
                     /locus_tag="VU722_000307"
     CDS             complement(24771..25715)
                     /gene="manA"
                     /locus_tag="VU722_000307"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU1771361.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGPGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFIVLSDVESWTLEGQDLELIVSHP"
     gene            complement(25836..26133)
                     /locus_tag="VU722_000308"
                     /pseudo
     CDS             complement(25836..26133)
                     /locus_tag="VU722_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380709.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            26198..27305
                     /locus_tag="VU722_000309"
                     /pseudo
     CDS             26198..27305
                     /locus_tag="VU722_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(27422..27769)
                     /locus_tag="VU722_000310"
     CDS             complement(27422..27769)
                     /locus_tag="VU722_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1771362.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVK
                     GPAGLVLDFYRMK"
     gene            complement(27880..29655)
                     /gene="spxB"
                     /locus_tag="VU722_000311"
     CDS             complement(27880..29655)
                     /gene="spxB"
                     /locus_tag="VU722_000311"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU1771363.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(29862..32105)
                     /locus_tag="VU722_000312"
     CDS             complement(29862..32105)
                     /locus_tag="VU722_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU1771364.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDETEVLGLATSLEEASQHPLAEAIVKRASEAGLEFHTVENFQALHGKGV
                     SGQINGKQVLLGNAKMLDGMDISSIYQEKLEQLEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLKTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKVHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(32115..32486)
                     /locus_tag="VU722_000313"
     CDS             complement(32115..32486)
                     /locus_tag="VU722_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU1771365.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYAPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(32497..32892)
                     /locus_tag="VU722_000314"
     CDS             complement(32497..32892)
                     /locus_tag="VU722_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU1771366.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      33076..33174
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33258..34049
                     /gene="thiD"
                     /locus_tag="VU722_000315"
     CDS             33258..34049
                     /gene="thiD"
                     /locus_tag="VU722_000315"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU1771367.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDTPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(34258..34890)
                     /locus_tag="VU722_000316"
     CDS             complement(34258..34890)
                     /locus_tag="VU722_000316"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU1771368.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(34883..35686)
                     /locus_tag="VU722_000317"
     CDS             complement(34883..35686)
                     /locus_tag="VU722_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU1771369.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVSASPIRKG
                     LVRDLLDYSPTILKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSILRRDENWLDTIKGEVYE"
     gene            complement(35686..36210)
                     /gene="thiW"
                     /locus_tag="VU722_000318"
     CDS             complement(35686..36210)
                     /gene="thiW"
                     /locus_tag="VU722_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU1771370.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(36215..36907)
                     /gene="tenA"
                     /locus_tag="VU722_000319"
     CDS             complement(36215..36907)
                     /gene="tenA"
                     /locus_tag="VU722_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU1771371.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(36918..37568)
                     /locus_tag="VU722_000320"
     CDS             complement(36918..37568)
                     /locus_tag="VU722_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU1771372.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(37570..38955)
                     /locus_tag="VU722_000321"
     CDS             complement(37570..38955)
                     /locus_tag="VU722_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771373.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(38956..39516)
                     /locus_tag="VU722_000322"
     CDS             complement(38956..39516)
                     /locus_tag="VU722_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1771374.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(39779..39867)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(40090..40719)
                     /locus_tag="VU722_000323"
     CDS             complement(40090..40719)
                     /locus_tag="VU722_000323"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU1771375.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(40721..41503)
                     /gene="thiM"
                     /locus_tag="VU722_000324"
     CDS             complement(40721..41503)
                     /gene="thiM"
                     /locus_tag="VU722_000324"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU1771376.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(41730..42398)
                     /locus_tag="VU722_000325"
     CDS             complement(41730..42398)
                     /locus_tag="VU722_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU1771377.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(42613..42701)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42955..44091)
                     /gene="lctO"
                     /locus_tag="VU722_000326"
     CDS             complement(42955..44091)
                     /gene="lctO"
                     /locus_tag="VU722_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU1771378.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(44715..46205)
                     /gene="lysS"
                     /locus_tag="VU722_000327"
     CDS             complement(44715..46205)
                     /gene="lysS"
                     /locus_tag="VU722_000327"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU1771379.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            46390..46770
                     /locus_tag="VU722_000328"
                     /pseudo
     CDS             46390..46770
                     /locus_tag="VU722_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(46857..47504)
                     /locus_tag="VU722_000329"
     CDS             complement(46857..47504)
                     /locus_tag="VU722_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771380.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(47501..48199)
                     /locus_tag="VU722_000330"
     CDS             complement(47501..48199)
                     /locus_tag="VU722_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771381.1"
                     /translation="MGKLSSHMWRLNQIIYAKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLVVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(48209..48961)
                     /locus_tag="VU722_000331"
     CDS             complement(48209..48961)
                     /locus_tag="VU722_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771382.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFHLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(48961..49725)
                     /locus_tag="VU722_000332"
     CDS             complement(48961..49725)
                     /locus_tag="VU722_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771383.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEV
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESYFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(49821..50224)
                     /locus_tag="VU722_000333"
                     /pseudo
     CDS             complement(49821..50224)
                     /locus_tag="VU722_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(50404..51036)
                     /locus_tag="VU722_000334"
     CDS             complement(50404..51036)
                     /locus_tag="VU722_000334"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU1771384.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(51070..51771)
                     /gene="pyrF"
                     /locus_tag="VU722_000335"
     CDS             complement(51070..51771)
                     /gene="pyrF"
                     /locus_tag="VU722_000335"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU1771385.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            52090..52182
                     /locus_tag="VU722_000336"
                     /pseudo
     CDS             52090..52182
                     /locus_tag="VU722_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(52505..53218)
                     /locus_tag="VU722_000337"
     CDS             complement(52505..53218)
                     /locus_tag="VU722_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1771386.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEEFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(53211..54044)
                     /locus_tag="VU722_000338"
     CDS             complement(53211..54044)
                     /locus_tag="VU722_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771387.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            complement(54254..55402)
                     /locus_tag="VU722_000339"
     CDS             complement(54254..55402)
                     /locus_tag="VU722_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU1771388.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYITLLFSKEA"
     gene            complement(55439..55627)
                     /locus_tag="VU722_000340"
                     /pseudo
     CDS             complement(55439..55627)
                     /locus_tag="VU722_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(55611..56618)
                     /locus_tag="VU722_000341"
     CDS             complement(55611..56618)
                     /locus_tag="VU722_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU1771389.1"
                     /translation="MRIVDKIKILPTPYEGQYHLYIPSSKKHVLVGKQEKKWLEQLIG
                     QEFTISDLLVLVGKKYYLRFYIVLSKMGLIDSMKSRKKINIFKISWDFNITLSEKLNY
                     KRFNKNFEKILFGIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISA
                     TIHEFSHAIIANNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIAS
                     NSILSLTGLLVLLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNL
                     NFQYIVQLLIAFVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLR
                     K"
     gene            complement(57200..58399)
                     /gene="divIB"
                     /locus_tag="VU722_000342"
     CDS             complement(57200..58399)
                     /gene="divIB"
                     /locus_tag="VU722_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU1771390.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(58409..59467)
                     /locus_tag="VU722_000343"
     CDS             complement(58409..59467)
                     /locus_tag="VU722_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU1771391.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(59471..60823)
                     /locus_tag="VU722_000344"
     CDS             complement(59471..60823)
                     /locus_tag="VU722_000344"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU1771392.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGTIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAVNEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(60927..61568)
                     /locus_tag="VU722_000345"
     CDS             complement(60927..61568)
                     /locus_tag="VU722_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771393.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(61570..63591)
                     /locus_tag="VU722_000346"
     CDS             complement(61570..63591)
                     /locus_tag="VU722_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1771394.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(63674..63973)
                     /locus_tag="VU722_000347"
     CDS             complement(63674..63973)
                     /locus_tag="VU722_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU1771395.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASTAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(64337..64591)
                     /locus_tag="VU722_000348"
     CDS             complement(64337..64591)
                     /locus_tag="VU722_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU1771396.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(64611..66452)
                     /gene="typA"
                     /locus_tag="VU722_000349"
     CDS             complement(64611..66452)
                     /gene="typA"
                     /locus_tag="VU722_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU1771397.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            66614..67339
                     /locus_tag="VU722_000350"
     CDS             66614..67339
                     /locus_tag="VU722_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU1771398.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(67379..67606)
                     /locus_tag="VU722_000351"
     CDS             complement(67379..67606)
                     /locus_tag="VU722_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771399.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(67695..68075)
                     /locus_tag="VU722_000352"
     CDS             complement(67695..68075)
                     /locus_tag="VU722_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1771400.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(68075..68344)
                     /locus_tag="VU722_000353"
     CDS             complement(68075..68344)
                     /locus_tag="VU722_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU1771401.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            68408..69316
                     /locus_tag="VU722_000354"
     CDS             68408..69316
                     /locus_tag="VU722_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU1771402.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(69370..70125)
                     /locus_tag="VU722_000355"
     CDS             complement(69370..70125)
                     /locus_tag="VU722_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU1771403.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(70146..71075)
                     /locus_tag="VU722_000356"
     CDS             complement(70146..71075)
                     /locus_tag="VU722_000356"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU1771404.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCAGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(71090..71713)
                     /locus_tag="VU722_000357"
     CDS             complement(71090..71713)
                     /locus_tag="VU722_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU1771405.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(71706..72944)
                     /gene="hflX"
                     /locus_tag="VU722_000358"
     CDS             complement(71706..72944)
                     /gene="hflX"
                     /locus_tag="VU722_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU1771406.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(72937..73821)
                     /gene="miaA"
                     /locus_tag="VU722_000359"
     CDS             complement(72937..73821)
                     /gene="miaA"
                     /locus_tag="VU722_000359"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU1771407.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSETKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            73942..74112
                     /locus_tag="VU722_000360"
     CDS             73942..74112
                     /locus_tag="VU722_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU1771408.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(74160..74999)
                     /locus_tag="VU722_000361"
     CDS             complement(74160..74999)
                     /locus_tag="VU722_000361"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU1771409.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLIQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(75096..76055)
                     /locus_tag="VU722_000362"
     CDS             complement(75096..76055)
                     /locus_tag="VU722_000362"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU1771410.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(76182..77180)
                     /locus_tag="VU722_000363"
     CDS             complement(76182..77180)
                     /locus_tag="VU722_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU1771411.1"
                     /translation="MNKRLFLKMSLATLPVLALFSQPVLAEENIHFSSCKEAWGNGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTATQINTSSATTSGWVKQDGA
                     WYYFDGNGNPVKNAWQGSYYLKADGKMAQSEWVYDSSYQAWYYLKSDGSYAYSTWQGN
                     YYLKSDGKMAQSEWAYDSSYQAWYYLKSDGSYAYSTWQGNYYLKSDGKMAKGEWIYDS
                     SYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGDDGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(77230..77847)
                     /locus_tag="VU722_000364"
     CDS             complement(77230..77847)
                     /locus_tag="VU722_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1771412.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSSYQKA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALVLSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMIGVSEELKTLDLTDIAGICPYPTLLICGSKDRPNL
                     SSMKTLHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKIRSFLELLK"
     gene            complement(77848..79569)
                     /gene="pabB"
                     /locus_tag="VU722_000365"
     CDS             complement(77848..79569)
                     /gene="pabB"
                     /locus_tag="VU722_000365"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU1771413.1"
                     /translation="MHRKTVIDFRALGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     KQGYYVVGYVSYEAAPAFEEKFAVHKAPLLGEYLLYFTVHDSVETSPIPLTYDEVDLP
                     SDWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVIEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNGRELATRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVEHLCQVEQYSTVWQMTSTIKSRLRADVDLI
                     TIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYQEVHQKAAVLYRKQARFQLITTGKISQKNLLFEA
                     QHLERLRKASRYFASPFDAEDLKQKIKEECQDCDVNQDYRLRISLSKSGEIEVNRQVL
                     TPLSRTFCYAQLCLQEANLQQAFTYFKTSHRPHLGLRKQEIIYHNAAGELLETSIGNL
                     VLKISGRLYTPPIELGILPGIYRQHLLERGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILQEN"
     gene            79756..81012
                     /locus_tag="VU722_000366"
     CDS             79756..81012
                     /locus_tag="VU722_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1771414.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINMDTHKEIIAKLDYDAPSCP
                     NCGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKASMTDIAHQLSISTSTVIRKLNDFRFKHDFSYLPEIMSWDEYS
                     FTKGKMSFIAQDFKKLNIIAVLEGRTQAIIRNHFLRYDRAIRCQVKIITMDMFSPYYA
                     LAKQIFPCAKIVLDRFHIVQHLSRAMSRVRVQIMKQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLTYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(81060..86996)
                     /locus_tag="VU722_000367"
     CDS             complement(81060..86996)
                     /locus_tag="VU722_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1771415.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVDKEVI
                     SQEAKDLIQTGNPDGDEVVYGLVYQKAQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASAFLVGAMGLVVLPNAGAVDPVATLAPASREDVVEMEGYRYVGYLSGEILKRLGLD
                     TVLEEASVKSGEVTVVEVETPQSTTNQEQVRPENQAVETEEAPKEQAPRTEESPKEEP
                     KSEVNPTDETLPKVEEEKEVSAEPAPVEEVSGVVESKTDEQAPVKSESQPSDKPAEES
                     KVATPVEQPKIPEQPVQPRTPKESSQEENPTENRGAEETPKQEDEQPAVIETKDEAAN
                     QLVEEPKVETPAIEKQTGPAEEPKVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVE
                     KAPKQEESTPDAKVEETVEPKEETKTAKDTQEEGHVDEALAQEQLPEYKVTEGTLVEE
                     TTTELNYKTETTDDPTKYTDEETVLRTGEKGSQVTKTIYKTVEGVKTDQVLSTSTEVT
                     KEHVNQQVSRSTKPIEGTLVEESLEKIPFKEKIEEDDQLKKGSEVVAQEGKEGQKKIT
                     KTFNTIKGVKTEDAPKVIEEVIEVPQDKILKRGTKIFEKPVLTITAVESKDLKRTSDV
                     KYSLENPSKATIKSITLTLKKGDEIVKTLIVSPDNLTASLTDLQYYKDYKLETKMVYD
                     RGEGDEEEVLNEESLRIDLKKIEIKDIKSTKLIKVSENKEEIDDTNFTTIPTDKNNYY
                     LKITTNDNKTNRLAVKSITEETVDGENFYKITSEATDLIQHTKEEQIKNEYTYYIAKP
                     KQKENNVYYDFGELVEAIQNNPEGDYKIGESLNATNIKPNGKSYITKKFKGSLTSTDG
                     NKFAIHNLANPLFNEIENATIKDLIFSNVNINKPNTEQIATLGKDATNTIIENIKITG
                     SIVGSNDVAGVVNNLNNGSKMKNVAVIGKLHTEGKKGWSISGLVNNQRKANIERVYTD
                     VEITGERARGSALVSTLDRGTDPRDVRANGHIKKAVAKGSINLKNNVETGGVISKNWP
                     YGFMEDVISYVKVTNAEKLYGSGDIGDDDFGFPYLSRVVSVAGEATGNVTRKNANRLK
                     EISKEEADKKLEDFGITAKDFEAPTLLVDKLNNNISKDDEYKTTQDYDKTKEQAYRNI
                     AKLQPFYNKEWIVNQGNKLTNENLLNKKVISVIGMKDNDFVTDLSEVNKILVHYSDKT
                     KDIFTVVQKDSNVSQIKEYSINELKDIVYTPNMIAKDRDSIASKIKEKLNSVELQSDG
                     MYNLMDKRNNPQENTTERRKRYVRDLFLEESFEEVKNNLDNLVNKLLLNYDFQLNESK
                     ASEDVLLQKIEANKEKIMLGLAYLNRYYGINFDNMNIKEIMLFKPDFYGKNVNFLDFL
                     IKIGSSEKNVKGDRTLEAYRETIGGIIGINELNGFLHYNMNLLTEYTNINDWFKDATK
                     KNVYIVEPETSIEDFKNKKHRAYDGLNNDVHSRMILPLLNLKKAHIFLISTYNTMAYS
                     AFEKYGKNTEEARNEFKKEIDKVAKAQQDYLDFWGRLASDKVRNKLLKSQNVVPSPVW
                     DNMNAPGYGWLDKYGYKDGSSDYAPSRELFGPTGRYFPPNWNMGAMAKIWDNPYKEES
                     VYYMVTDMISDFGISAFTHETTHINDRLAYLGGWRHREGTFVEAFAQGMLQSPSVSNP
                     NGEYGALGINMAYERNNDGNQWYNYNPNKLKNRQEIDDYMKRYNEAMMLLDYVEAESV
                     LSKNLSDNSQWFKKVDRKMREKGSYNNNLVAPNQWDLVRDLNEDEKVIKLNTIKDLVD
                     NNFATRHGVGNGVFKPEDFTPNSAYVTVNMMAGIYGGNTSEGAVGALSFKHNTFRMWG
                     YFGYEKGFVGYASNKYKDIANKENNGLLSDKLIIQKVSEGRFNTLEEWKNSWYEEIYN
                     KATTKGFVPISVDNEQISTYARLKELFNEAVQKDLNELSNQTIKNKYRHTVALKEKVF
                     KQLLKESDGFSGDLFNTSQA"
     gene            complement(87018..87581)
                     /locus_tag="VU722_000368"
     CDS             complement(87018..87581)
                     /locus_tag="VU722_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU1771416.1"
                     /translation="MNETQIQRETRQILEDVLEKANLKQGSIFVLGLSSSEVIGGQIG
                     KESSQEIGELIVETILGILGTRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVLPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPLLREIGHA
                     HVTALASRPKLIGGARAHYPQDSIRKS"
     gene            complement(87697..89388)
                     /locus_tag="VU722_000369"
     CDS             complement(87697..89388)
                     /locus_tag="VU722_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1771417.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLAVVGTFYYRSSSSAIEATIEGD
                     SQTTISQTSHFIQSYIKKLETTSTSLTQQTDVLAYAENPSQDRVKGIQNLFLTILKAD
                     QDLKTVVLVTKSGQVISTDDTVQMKTSSDMMTEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTLDHQSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     MWTLLWASVTSLFAFLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAEETGAYELR
                     EVTRQFNAMLDQIDQLMADIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFQ
                     DSQRVVQVTKSLATYFRLALNQGKDLISLSDEINHVRQYLFIQKQRYGDKLDYEIAEN
                     PAFDHLVLPKLVLQPLVENALYHGIKEKEGQGHIRVSVQKEDTGLVIRIEDDGVGFQA
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSSPQKGTKVEIYINRIETS"
     gene            complement(89385..90122)
                     /locus_tag="VU722_000370"
     CDS             complement(89385..90122)
                     /locus_tag="VU722_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1771418.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRHDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEGR"
BASE COUNT        27020 a        19414 c        16029 g        27805 t
ORIGIN      
        1 tttaattcta ggtttactag attctgtggt tctatctatt tattcggaaa agaaagtcta
       61 gtacagaagt catgctatgg aaacagctag tgtattagaa gtttgaacaa ggcttgggta
      121 acagactttt gaatgaagtc caagcaacaa ggagaaatct ccaccatgag tccattccat
      181 gactctgttg ctctagaaaa ccttgcaata gtcaagtgat aacgaataaa actttggatt
      241 gaaatatccc caagattatc tattacgagg agaaatctta acctttatca tttttaaaga
      301 aatatagtaa aatgaaacaa gaacaggaga aatcgatcag gacagtcaaa ttgattgcta
      361 acaatgtttt agaagttgag gtgtactatt ctagtttcaa tctactatac atgtaaatct
      421 ctactttcgc aaaatggatt ttcagaacag tatcccagta tagttaaaaa ctataaaaaa
      481 gagaggacgt tcccctctta aaatcttatt ttactgcttc tttcaaagca tctaccttat
      541 ccaaacgttc ccatggaaga tcaatatctg tacgtcccat gtgaccgtaa gccgatgttt
      601 gacggtaaat tggacgcttg aggtccagca tttggataat ccctgcaggg cgaaggtcaa
      661 agatttgacg agccgctttt tcaagttgac tttcagctac tgttcctgta ccgaaagtat
      721 cgatacgaac agaaacaggt tgcgcaacac cgatagcata ggccaactgc acttctgcct
      781 tcttagcaag gcctgctgca acgatattct tggcaatata gcgagccgca taagaggctg
      841 aacgatccac cttagtcgca tctttaccag agaaggcacc accaccatga cgagagtagc
      901 caccataagt atctacaata atcttacgac cagtcaaacc tgagtcccct tgaggaccac
      961 cgattacaaa acgacctgtc ggattgataa agaattttgt cttatcatca agataagaag
     1021 atggaataac ttctttgatg accttgtcaa tcacatcttg atggatttgt tcattagtgg
     1081 cctctggatc atgctgagta gaaataacga ctgtatctac acgtaccgga cggtcatttt
     1141 catcgtactc aactgtaact tgtgattttg catctggacg gagatagcta atttctccag
     1201 acttacgaag ttctgccaga cgacgaacca atttatgact gagtgcaatt ggcaatggca
     1261 taagctcttc tgtttcatct actgcaaatc caaacatgag cccttggtca cctgctccaa
     1321 tcaagtccag tggatcttga tcagcatttc cacgaacctc caaggcttcg ttaacacctt
     1381 gagcgatgtc aggagattgt tccaccaaag atgggtgtac tcccaccgtc tcagcagaaa
     1441 atccatattc tgtattggta taaccaatct ctgcaatggt atcacgaacc acacggttaa
     1501 tatccacata ggcatttgta gaaatttcac caaaaacgtg gacagaacca gtatatacag
     1561 ctgtttcagc agcaacgtgc gcctctggat cctttgctaa aatagcatcc aaaatcgcat
     1621 ctgaaatttg gtctgcaatc ttatccggat gcccctcaga tacagattca gacgtgaata
     1681 atttacgttc tgacataaaa atgtcccccc ttaaaaaata ttgttataga gttacaaagt
     1741 actgatagga aaactcttcg taataaatac ctaccatctt atcgggacta tataacttta
     1801 tcattatagc atttttaatc gcaatttgca gtctttaatg tagtgtttcg gtttagatag
     1861 ttcgttctca taaagcaaaa agttggagct cagtactcca acaatttcta ttaaaatgtt
     1921 tgacgtttag ctttacgctc tgcacgaccg cgagcgcgat tttcagcacg cttggtttta
     1981 cggcgctttt catcaaccgc ccattgaatt ttcttcttat aacccggttt gacttttttc
     2041 tttttctttt taaccaaacc aatcatttcg atatcaagtt tatcttgttt tttctcacgg
     2101 ttggcacgac gatcacggtc ataggtatct tgaaattccc cgtctttgac catcttagga
     2161 ctaaacttga ttcccaattt ctccaactca cggatatccg agtcatcact tggctgataa
     2221 agggtaatag ctgtacctgg taggccattt cgtccagtac gaccaacacg gtgaacaaaa
     2281 aaagataagt cttgcggaat ggcatcattg atgacatggc tgacaccttc aatgtcaatc
     2341 ccacgtgctg ccaaatctgt tgcgacaata tactcaaaat ccagattttg cacctgattc
     2401 atgattcgct tgcgttcacg aggggcaata tcgccatgga tttttgcaac cttcaagcct
     2461 tgagcagtca gatatgaatg caattcatca gcacgcgttt tagtgttaac aaaaatcatt
     2521 gccaaatacg gctgcatcaa ctgagtcaac tggtaaattt gagcattctt atcatgtccc
     2581 ttggtcgaaa tcaaccaatt atcaatggtg tcagaaataa ccgttttggt cttaattttc
     2641 tccataacag gattggataa gtattttttc aagaatggtt gcagtttttg tgggatagtc
     2701 gctgagaaga ccatgaattg caagtctttt ggaagactgc cagcaatctt atcaacagtt
     2761 tccaagaatc ccatatccaa ggtcatatcc gcttcatcaa caacaaatgt cttggcttta
     2821 tgaatagcta aatcaccaga tttaaccaag tcgtagatac ggcctggtgt tccaataaca
     2881 atatgaggct gattgcttgc caatttctca atctggcgag ccttatccgt accacccaca
     2941 taattaacca cacgaacttc gacatctgag tgagctgaaa tctgacgcgc tacttggtaa
     3001 atttgagtag ccaactcacg actcggtgca gtaatcactg cttgtacact atcgctagct
     3061 tcatctaatt gctggaaaat cggtaacaag aaagtatgag tcttacctga acctgttttt
     3121 gattctccta ctaggtcacg acctgccaaa acaataggaa tcaacttgtc ttgcacctct
     3181 gttggagttg taaattttaa ctcctccaag gcttctctaa tatagttttt aaattgaaat
     3241 ttcgtaaatg acataacatc ctcgattcta tctatcttat caattatacc atattttatt
     3301 ccattacagt agtctcactt atttaggcta tttccagtag cttctctagt aagaaaaggc
     3361 tggaatttta tagttccaac ctcttttcag ttattatttc cagtttaaca tagcattcaa
     3421 gccatagtga tcactcactt gtggactctt gttaccatca aatacgacat gtaaattttc
     3481 caccgctaac tctttggtag taaagacata atcgattcga aggggttcag tgttcccttt
     3541 ccagccatca atttcaagcg gaacagtata gctaccactt ttctcttgag caacttcaaa
     3601 tgcgtcttgt aagcctaatg gactagctaa aatagcttgg taaccttcct gacctgctgg
     3661 gttgttaaaa tctccagcta gtaaaagtgg cttgttcaat tttttcaaga cagcctcaaa
     3721 tcgtgcccat tcttcttgaa aacctttatc ccaccaagag agatgaacac tggcaactgc
     3781 tagctccttg ccatcgacta cagtttcagc tagggcaaca cggcgagtat gatagtctgt
     3841 tggatcatcc acatctgaaa ccaaaatttc tctggcttca ataggtgttt tagacaagat
     3901 agccacacct tcgtggtagc ggtcatagcc gatatggtta taggcccagg tccagtagta
     3961 atttttccct tgctcagata acttttcaac caagagtcta acatagtgat cttggtgaat
     4021 aggctcagct gctggcaaag cttgataaag gtcattaacc tccacctctg acgaggtcat
     4081 ctcctgatta atttcttgga aacaaatcaa atcatagtcc ttttcaagaa tatcttcaag
     4141 caaaatctgg aatttttcct ctgcttcttt ctccatccaa ctatgagtat tgagtgttaa
     4201 aaatttcatt cttttctccc aaaataagag gttggaatac agcttccaac ctcaagtata
     4261 ttacaattct actttagcaa ctgctgtttt agctgcaaga gaacctgttt tttctaattt
     4321 aactgattta attgcatcac catttgtgaa gacaactact gttgaagttt cacgtcctgc
     4381 tgcacggata gcattcaagt cagctgtgac aaggagatct cctgctgcaa ctttttgtcc
     4441 ttcagcaaca tgaactgtaa atggtttacc ttcaagactt actgtgtcca aaccaatgtg
     4501 aaccaatact tcaagacctg cttccgtcac aataccaaaa gcatgttttg ttgggaagat
     4561 gcttgataca gtacctgaaa ctggagatac aatgtttcca tttgcaggtt ctactgcaaa
     4621 tccatcaccc atcatttttt gagcaaatac tggatccttt acttgttcca aagcaacaac
     4681 ttgaccgtct gctactgagt aaacttcctc agtaagatct ttgaagtgaa cagtgttttg
     4741 ttgtacttca gtcatttggt ttggaagagt ttcaggaatg atttcacctg aatcaaggat
     4801 atcttggata tcagatttca aaatgtcagc ttttggaccg tagatagctt gaaccccttg
     4861 tcctttcatc acaagaccca tagctccttc tgctttccat tgctctgcat ttcctacttt
     4921 atctgcatct ttaacagtta cacgaagacg agtcatacat gcatcaacat caacgatgtt
     4981 tacacgtcca ccaagaaggt tgataatgtt tacagcttga gagcctgctg caactttcac
     5041 ttcgctgctg gtttcttctg aaccttcagc agtttcgtag tttccgttgc gccctggagt
     5101 tgcgtagttg aatttttgaa tcatgaagtt tgcgataaag tacatgatta cagcaaagag
     5161 aacagttacc caaacgaagt taacgatatc cataccaata ccagcactga ttgcaatagg
     5221 tgtacgagtc aagaactcga ttgaaccgaa tgagtgcata cgtaggttta cgacgtcagc
     5281 catagcgaag gcagcacctt gaacaagtga gtaaacaaga tacataggtg ttgcgatgaa
     5341 catgaacatg tattcgattg gttcagtaac ccctgtcaag aatgttgcaa gagctgttgc
     5401 aatcatcata cctttgtatt tatgtttctt gtcagcatca acattacggt agatagcaac
     5461 aatcacaccc atcaagatac cgaatgaacc gatcatttgt ccaactttga aacgagctgg
     5521 atgtactgta tctaacaagt gttggtattg actagcatca gtacctttaa ggtttacaag
     5581 gtctgttacc catgcaagcc atagtgggtc ttgaccgaat acttgagtac ctttagctgc
     5641 accagttaaa atgtcataag taccaccaag agctgtgtag ttcattggga tagtcaacat
     5701 gtggtgaaga ccaaatggca agagcaaacg ttccaaagta ccatacaaga atggtgcaag
     5761 aattggagca gtttcttgtg agttggcaat ccagataccg aaattattga tacctgtttg
     5821 aactactggc cagaaagcag caagtagaat tgcagcgatt gctgaacgaa gaataactac
     5881 aaatggtacg aaacgtttcc cgttgaagaa tgaaagtgca tcaggaagtt tacggaagtt
     5941 gtagtatttg ttgtaagcag ttgcccctac aaaacctgag ataatcccta cgaatacccc
     6001 catgttcaag gctggagctt caagaacact gataaagtaa tcagcaactt tgattgaacc
     6061 accaaagaaa gtagttacca tagcatctgg atttttcaac atatcgcctg atacaccaaa
     6121 gattgtacca gtgatacggt taatcaagat gaaggcaaga ccagcggcga aagcaccacc
     6181 agcacgttct ttagcccagc ttcctccaat ggctagggca aacaaaatgt gaaggttacc
     6241 gataaccccc caaccgattt gctcaagaat tccacctgtg atgacaagtg gtgtaaaggt
     6301 tgggttaatc atcacgatag acttaccgat tgaaatcatc aaaccagcag ccggcataac
     6361 cgcgataact accatcaaag ccttaccgaa tttttgccaa aattcgaaag acaagacatt
     6421 tttgaatgta tctttcatca ttcaaatctc ctttattttt atttaggcaa acgtttcacg
     6481 aaaacgtttg caccttctat gatttaatta taccacttta attttttttg taaaggcttt
     6541 tataaaaaaa ttacactttt ttctaaaaaa tttctagtgc gccaaatttc aagttcaaat
     6601 tagccatcaa gaagtcttct ctgggggact tctttggaag cccttttctt ctacgcatct
     6661 cttttcaaaa actcttgtag caaaaaagga gattttgcaa tctcctcata aaagcagcta
     6721 ttttacctaa atcttcaaga atcggcgcat ggatattcct gatcccaatg aaccaatgaa
     6781 aaccccaatc acaaatagta gggcaatcat caacggacta aataaatctg gactaatcat
     6841 ggatagattt tgccctacca acgatttgtt gacagattgg taaacaattt gataaacaat
     6901 aaagaccaaa acagatggtg cgatagctcc caataaaccg ataaaggctc cttctaacaa
     6961 gaacggtcca cggatataac tgtttttagc tccgaccaag cgcatgattt gaatttcgcg
     7021 actgcgggaa ataatggtaa tacgaatggt atttgaaatc aagaaaactg cgataaaaat
     7081 taacaaagca gcaatcccta gtccccaaac acggataaat gaagctaact tgaagagtct
     7141 ttctgtattg gcaccgccat cttgaacctc agagacacct tcaatttttt tagcctcttc
     7201 ggctatagtt tttacatcat ttggagtgtt tgcctctaca atataggcat catagagagg
     7261 attagcatct ccttcaaaga ttttccagtt atctcccatt atctcggtta atttttcata
     7321 ttgttcttct ttacttgaaa aggtaacact tttaaccgta gacatgttct tcaaagaatc
     7381 atataccttg tggtagtcat tatttgtaac agtttgacct tctttttcaa ttgtctgact
     7441 attatcttcc acatcctttc ggatataaac tactacacgg acattatttt caatatctgt
     7501 agctagtttc gctgtattga aaataacaga tgcaaatatt gccaccaagg tcaaagtaat
     7561 catgactgaa ctgacagcag ctactgtcat ccaaccattt cgtttcaaac tttttaaggc
     7621 ttcaaataaa tggcgaaaaa atctactaat catcgtatcc atactctcct tttgattcgt
     7681 cacgaacgac acggccattt tcaatggcaa tgacacggtg gcgcaaggta tttacaatct
     7741 ggctattatg agtcgccatc aaaatagttg ttccttgtag gttaatccgt tccaagagat
     7801 tcataatttc ccatgaatta tccggatcca gatttcctgt tggctcatca gctatcaata
     7861 ctttgggatt atttacaatt gcacgcgcaa tcgcaatccg ctgttgctcc ccacctgaga
     7921 gttcatttgg gaaagaacga accttatgct tcaatccaac caagtccaaa acttccatca
     7981 ctcgtctttt gatattacgg cgattttccc cgattacttc catagcgtaa gcaatatttt
     8041 catagacagt tttctttggt aacaatttat aatcctggaa gacaacccca acactacgac
     8101 gtagaagcgg gacatctttc tttttgatct taaccagatt aaaaccagca actgataggc
     8161 ttcctttatc gatttttact tcacgataca gagaacgaat aaaagttgac ttccctgctc
     8221 ctgaaggtcc tacgatgtaa gcaaattccc ccggttgaac gctgaccgaa acaccgcgta
     8281 gagcagtcgt tccgttgtcg tattttttaa cgacatctct catttcaata attgacatgt
     8341 gagttccttt ctatcttagc taattcgcca cttgagataa gcatcgataa aaccatctag
     8401 gtccccatcc ataaccttat ctacctgagc aacctcaaag ctagttcggt gatcttttac
     8461 catagtataa ggcgtgaaga cataagaacg gatttggctt ccccaagtga tctccttttt
     8521 ctcacctttg agagaatcta cctccgcagc cttcttctct tgctccattt gatagagctt
     8581 agcctgcaac atcttcatgg cacgatctct atttccatac tgggtacgat ccactgttga
     8641 ttggacaaca attccagttg gaatgtgggt taaacgtaca cctgttgaaa ccttattgac
     8701 gttttgtcca ccggcaccac ctgaacggaa ggtatccatc ttgatatcat cttcacggat
     8761 ttccacttca atagtatcat ccaattctgg catcacttct acagatgtga aagaggtatg
     8821 gcgacgtttg gcagagtcaa atggtgagat tcgcactaag cggtgaacac ccatttctga
     8881 cttgaggaga ccataggcat taggcccttc aaatgataaa gttaccgact taataccagc
     8941 ctcatcacct gcttggtaat ccaacacttc cactttaaag cctttagcat taccataacg
     9001 agtatacata cgaagcaaca tatcacccca gtcctgcgcc tcagtaccac cagaacctgg
     9061 atggatttcc aagatggcat tgttgtggtc ataaggttct gacaagagta gagtcatctc
     9121 gtagctggtc attatcttat caagttcggc taactgcgct accagttcat catgcactga
     9181 ctcgtcttca gccaaaaaat ccaataaaat ttcgacttca tcctgcaact cttccatctt
     9241 atggaaggta ttgtaagtgt tttttaattc atttaattct tgcgacgttt tttgggccgc
     9301 aatattatcg ttccaaaaat caggttctgt catcttgttt tccaagatga caatctcttc
     9361 ctctagccct tcgaggtcaa agagaccccc tgaaagaagc taatttttca cgatttgcgt
     9421 caattttctg acgaattact gaaatgtcca taaatactcc ttttttacat tatttcatta
     9481 tagcatattt tatcatttct ttccatcttt ttctctaatc cccttttcat gaaaaaagaa
     9541 gcctttgggc ttcccttctt acaagacttt tgctgaagtg cgagcgattt cttccacttg
     9601 aataccattt gcttcaaatt tttctttcaa ggctggtaaa tcaattgatc catcgatttg
     9661 cacttcgata atcaccttac catccttacg cggaatattg actgtatggg agatattcaa
     9721 attttcttct acaatcaaag aaacaatttt tccaagaaca ccaacttcat cttctgtaac
     9781 aaagcgtaca cgaatccctt cttcgccata acctgcaatt tcaagaaagg cttggaaaac
     9841 gtcacggtca gtaataactc cgtatacttg atggttatct acgacaggga gaatactaat
     9901 cttatttttc aacatcagat aagttgcatc ttctagacta gcatagcctg agacagtgac
     9961 aacatcgcga atcatgacat cttttacttt tgtcttattc agaagataat tcatctcata
    10021 gatagaaaga cttgttgctt tagatggact tgcttgtgca atggttccct cagtcaccaa
    10081 accaactaat tgatcatttt cgataacagg cagacggtgc aaaccttgct ctctcatcaa
    10141 atctgctgca tgagatactg ttgtatctgg actaatataa actaccttgc gggtcataaa
    10201 atctttaact gccatgagac ttctcctttt ctattcttat ccctattata caatcttttt
    10261 gtaaatctat caaacgctta catttctttt tcgaaattca gaaaagtatg aataagctag
    10321 caaaaagagc tctgaaatcg agctctgtga atgaaggtaa gaaatttttc attcgatttt
    10381 ttcaattatt agaaattaag ctttcaatgt agatgcagat ttgtttgcaa tctcaatcta
    10441 ccgactaaaa aggtcccccg gactatattg atgattactt cgtaatctcc atctgccgac
    10501 taaaacaatc cactggattg ttttagccac ctagatatgc ttttctgact tcttctgatg
    10561 aagcgagttc ttttcctgtt cctgatagga cgattttccc tgtttccagt acatatcctc
    10621 ggtcagagat tgcaagtgct ttattggcat tttgttcaat caagaggacc gttgttcctt
    10681 gcttctgaat atcttgaatg atatcaaaaa tttcttggat aaagattggg gcaagtccca
    10741 ttgatggttc atctaaaaga agaagttttg gtgttgacat gagggcgcgt cccatggcaa
    10801 gcatttgttg ttccccccct gaaagagtgg ctgcatcttg gttcttccgt tcttcaagac
    10861 gaggaaagcg tgagaaaacc ttcttcaagt tagcttgatt ttcttcacga tttttcttta
    10921 agaaagctcc catttcaaga ttttccataa cagtcaagcc aggaaagacg tggcgtcctt
    10981 ctggaacttg tgaaagacca cttgccacga ttttctgagc tggcattttt tggatttctt
    11041 gacctaaaaa ttcaatcttt cctgaacttg gtcgaaccaa acctgacaag gtgcgaagaa
    11101 tagttgtctt acctgcaccg ttggcaccga taagggaaac aacttctcct tcattaactt
    11161 caaagcttac atcacggact gcttggatca taccgtaatg cacagaaaga ttttcaactt
    11221 ttaacataga cattaggctt cacctcctag ataagcttcg ataacgcgtt tattggtctt
    11281 aatttcgtct ggagttcctt gagcaattaa acggccatat tcaagtacgt agatacgttc
    11341 tgttacttcc atgaccagat tcatatcgtg ttcaatcaac atgattgtaa tcttaaattc
    11401 atctttgata cgacgaatta actcagtcaa ttcggctgtt tcctgtgggt tcatacctgc
    11461 tgctggttca tctaagaaga gaattttagg ttccgtagca agggcacgaa caatttccaa
    11521 acgacgttgt tgtccgtagg aaagattttt agcaagagtc tctgcatcac catctaaatc
    11581 aaagattttc aacaattcca aagctttagc ctttaattct ttttcactct tgtaaaaagc
    11641 tggtaagcgt aagaaactag taaaaacatg ctgtttgtga tggtttccaa aagcaatcaa
    11701 aacattatct aaaactgtta aatctttaaa gagacggata ttttggaaag tacgtccaag
    11761 tcccaaagag gcaatcttat aaggtgattt cccattcaaa aggtgaccat ctagggttac
    11821 tgttccctcg cttggttcat aaacaccggt caaaaggttg aaaagggtgg ttttcccagc
    11881 tccgtttgga ccgattaatc caaccagttc cccttcgttc aattcaagag tcacatctcc
    11941 aacagctgtt agaccaccaa aatgtttggt taactgtttt acttcaagta atgccattag
    12001 ttttgttcct ccttcttaga ttttttaaag aaacgtgata ggctcagttc ccatgttcca
    12061 aggagtccac ctggtctgaa aatcattacc aataccaagg ccaaagcgta aataatcata
    12121 cgcacactag taacatcttg gagaagcata ttcaaaattc ccagaacaat agccgaaaca
    12181 atcgcacctg taatggaacc gagtccacca aatacaacaa taatcaaaac gttgattgag
    12241 ttgatgaagg tgtaatcttt cggtacaaca gacccgataa atcctgcctg aagtgaccca
    12301 gcaatacttg cagtaatggc accaaagaca aaagcgatga ttttaatttt agtcgtatta
    12361 accccaactg actcagcagc gatttcatct tcacgaacag agagggttga acgaccaatt
    12421 gggctacgca agaagttcaa ggttgcaatg gttgtaatca cgacaaagaa gtaaaccatt
    12481 tgccaagttg taaagttagg aatccctaag atacctgccg caccatttgt aaggcttcca
    12541 ccattgatga taaagatacg gataatttca gaaacaccca gagttgctac cgcaagatag
    12601 tcccccttca agcgcaaggt tggaatgccg acaagtaagg caactgctcc tgaaagcaaa
    12661 gcccctacaa gcatagctcc aaagaaggca ccgtaggttg gtgatttaga accaataata
    12721 gctgctgcat aggcaccaat cgccatgaaa ccagcatgac caagtgaaaa ttgtcctgaa
    12781 aaaccaacga ttaagttgag accaacagtc aaaataatat taattccaat ttgttgtaaa
    12841 atctgtacat agaatagatt aagtactccg actgaaacca gtacactaat caagctatag
    12901 ccagctaaca aaaggagtaa ccatagaata ttaactttta aattttcctt catcgtttac
    12961 accttctctt tcacattctt accaaggata ccagctgggc ggacaatcaa gatcaacaac
    13021 aagattccat aaacaatggc atcacggaaa tctgacatcc caaaggctgt cgcaaaggtt
    13081 tccaatagac caatcacaaa gccaccaaga gcagcaccag gaataattcc gataccacca
    13141 agtactgcgg caacgaaaga tttaagacct ggagtaaccc ccatcaaagg ctcaagagag
    13201 ttataataaa gagcaatcag aacaccagcc gcacccgcaa gagcagaacc caaagcgaag
    13261 gtaaagctaa tcgtacggtt tacattgatc cccatcaatt gcgccgcgtc gctatctact
    13321 gatactgcac gcatggcttt ccccatctta gtcttttgga caatgacttg taacaaaatc
    13381 atcaaaatca aggaaatgcc caaaatcatt aactgcacat ttgttaagct aattggtccc
    13441 aaatcatatc gaactgtttg aatcgcttga gggaaggcac gggtattggc accaaccaga
    13501 tagaccattc catactccaa taggaaagaa accccaatag ccgtaatcaa aacagcaata
    13561 cgagtagagt ggcgcaaagg tctgtaagca agaaactcaa tcacgatacc aagaatagct
    13621 gtcgctagca tagctacaat aagcgctaca aagaaattca tttggaaaga attgatcaag
    13681 aaataaccga taaaggctcc catcatataa atatcaccat gggcgaagtt gatgagcttg
    13741 ataattccgt aaaccatggt atatcctagg gctaacagcg cgtaaacact acctagaatc
    13801 aaaccattta cgagttgttg gagcataaga ttcactcttt ctatttataa ttccgagggg
    13861 tttccctcac tttttgatag gttcttatac tcaatgaaaa tcaaagagca aactaggaaa
    13921 ctagccgcag gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt
    13981 cacatatata atccaaggcg acgttgacac agtttgaaga gattttcgaa gagtattaaa
    14041 catcgaaaca gggagtgagt caaaggctca ttccctattt caacattttt ctattatggt
    14101 tttacaactt ctgctgcttc aactttacca ttgttcatgg tcatcatgta agcagttttg
    14161 actgtgttgt ggtctgcatc gaagcttgtt tgaccagtta caccttcaaa atcttttgtt
    14221 ttagcaaggt tatccttgat ttcacctgaa tttttagcac cttttgctgc gtttgctaca
    14281 aggtgaactg aatcataagc caaggctgca aatgttgaag gctcttcatt gtacttagca
    14341 cggtaagcgt caaggaaggc tttagcttta gctgaaactt ctacagtagt tgaaaagcct
    14401 gagataaagt agatgtttga tgctttttca gcagttgctt gttgtacaaa ctcctcaccg
    14461 ttgaatccat caccaccaac gattggtttg tcaattccca tgccacgcgc ttggtttaca
    14521 atcttaccag cctcattata gtaaccagga acaacgatag catcaaagtc tttccctttc
    14581 atttttgtaa gggctgcttg gaagtctgtg tcacctgcta cgaaagtttc atctgcaacg
    14641 atttcaccct tgtatgactc gcggaaagat ttggcaatcc ctttagcata gtcactggca
    14701 ttgtcagtgt aaagaacaac tttcttagca tttaattttt cagaaacata gtttgagata
    14761 atttttcctt ggaagctatc ttggaaagtt ccaataaaga ggtaatcttg acctttagtc
    14821 aatccatctt gagtcgcact tggtgagatc aatggaacac ctgcttttgt agcgttcgct
    14881 accgcagctg cagtcgcacc agatgtcgca ggtcctacga ctgctgatac tttagattgg
    14941 gttacaaggt tagttgtaac tgaagcagcc tcagctgttt cagacttatt atctttatcg
    15001 attacttcga tttgttttcc atcgatacca cctgcggcat tgatttcatc aacagccaat
    15061 tgggcacctt tttgttcagc tgttccgtat gcagctaaag aacctgattc ttcaaagtta
    15121 aacccgattt taattgtctt ttcctctact gagttaccag cagtgttgac tgctccagac
    15181 ttcacttctc cacaggctgc aagaagtgct acacttgcaa gcgccacaaa cgatagggca
    15241 aattttttct tcatcttttt tgtctcctta tttcttaaat agtctgttaa gaatataccg
    15301 aattatcaga aaattgtcaa tgttttcctt gaactttttc gatgataacg ttttcctatc
    15361 gataaagatt gcccacaaag ggtgtttcca actcttggat atgacaaacc ctaacttttt
    15421 taataaattt ttccttgctc aagcgtccga ccaattgctc cacttcttga gttggaacat
    15481 agagttgtaa gtaacgatgt ttcttggaat gataggtaat atctccataa tcctgcagtt
    15541 ttttggcatc acgattatag taaagataga taatcaagcc agagcgattg actttttcaa
    15601 acatgataaa tcctctttct aagaaatctc tccctattat accaaaaaaa gcaaacccag
    15661 tcgagtttgc cttctatcat cattagttca atgaattgtt ggccataatt tcatcaataa
    15721 agccatattc aagtgtttcc tgggcgctca tccagttatc acgttctgca tctgcatgga
    15781 ctttttccat tgactgacct gaattttcag ccaagatttt ttccaaggta ttacgagttt
    15841 tgagcaagtg ttctgcagcg atagccatat cagtttgttg ggtaccacca cctgtaccgc
    15901 ccattggttg gtgaatcatg tattcagcat ttggaagcat gaaacgtttg ccttttgctc
    15961 cacttgatgc gatgacagtc cccatagatg cagccattcc cataacaatg gtttggacat
    16021 ctgccttgat aaagttcatg gtatctacga ttgccaaacc agctgaaaca gaaccacctg
    16081 gtgtattgac ataaaggtaa atatcttttg tactatcttg ggcatccaag aaaagcaatt
    16141 gggcaataac agagttagcc atattgtctt caaccggacc tgtcagcata atgatacggt
    16201 ctttgagaag acgtgagtaa atatcgtaag aacgttctcc acggcttgtt tgttcaataa
    16261 ctacaggaat cattcatttc tccttttgag ttttaatttt gttggtcaaa tgactgaaga
    16321 taagactatt ataatatctt ggtcaaaaaa ggtcaaattt ttgctctgct ttcattagac
    16381 agaaacaaaa acccaacctc ctttcgtgac tagaaatact tttccaagtc attcttcttt
    16441 tcgatcttat tttgtaccga acaagcggtc tccagcatct ccaagacctg gaacgatata
    16501 accgtgttcg ttcaaacgtt catccaaggc tgctgtaaag atttctacat ctggatgagc
    16561 ttcttgaagg gcttttacac cctctggagc agatacaagg cagacaaatt tgatatttga
    16621 tgcgccacgt tttttaagag aatcaacagc caagattgct gagccacctg ttgccaacat
    16681 tgggtctact acaaaaattt gacgttggtc aatgtcctca ggcaatttca ccaagtattc
    16741 aactggttga agtgtttctt catcacggta cataccgatg tggccaactt tagcagctgg
    16801 aaccaagctc aagagaccat caaccatccc gatacctgca cgcaagattg ggacgatggc
    16861 caatttctta cctgccaatt gtttttgaac tgtttttgta attggtgttt cgatttccac
    16921 atcttctagt ggaagatcac gaagtacttc ataccccatc aacattgcaa tctcatctac
    16981 tagctcacga aaagcttttg tagaagtatc tgtacgacgc aagattgaca atttgtgttg
    17041 aatcagtggg tgattaataa cttcaatttt tcccattttt ggaattcctt ctttcaattt
    17101 attcttctta ttataccaaa aaacggttta aaaatctttc taaaccattt atttttgata
    17161 atttttacat tagatcagcc tctttaagag ctgtctgtac tgtctcaagt ggtaaatggg
    17221 tcaattctgt ccctttttct tgataaaggt attgggcgta gtcgtccatt cggtactggt
    17281 tgatataaac cacgcgcttg cagccgacct gaagcaattg ttttgtacag ttgagacaag
    17341 gaaaatgggt tacataggct gtaaagcctt tgggaacacc acgctcagca ccttgaagga
    17401 tagcattgac ctcagcgtga agggtgcgaa cgcagtggcc ttcaatgacc aaacattcgt
    17461 gatcaataca atgctcagtc cctgacaccg aaccattgta accagtggaa ataaccttat
    17521 tatcttttac cagaatcgcg cccactttag cacgtttaca agtggaacga ttcgcaatta
    17581 gtagagcttg ggctgcaaaa tactcatccc aggccagtct tttttcagtc atctcttttc
    17641 tcctttttct ctatttttta aaaaatggta aacctaaatc tgcaatcttt tcagctggta
    17701 ccttcatgcc atccttgatc cattttagaa ggacagagac gatggctgag ctccagaagg
    17761 aatgaagata agagctgaca ccttttgatt tcccatggta tttttctaga aattcctgca
    17821 tggcttggac aaagattttt tccagatggt aatccaaggc caattgaatt actctagctt
    17881 cctttctggc ctcccggaaa aggtgaaccc aaaccaaata aaggtctgtc tttaaatcgt
    17941 aatgatgcag ctgttccata atattgtgga cagttcgttt aaagacgctc tctaaaattt
    18001 cctctttgga gtcataattg cgataaaagg ccgcacgcga aacacctgca cgtttgacca
    18061 attcagaaat actaatcttg gtcagttcct ttttttccaa gagttgcaag agggctgttt
    18121 caatggcttc tctggttaat aaattggatt cttggtttga ttttctgaga ttttcaagag
    18181 acttttcaga gattctacgt tcagacataa cattttcttt ctacttgtca caacagacgg
    18241 atgatgcttt tgtttcaagg gttttcatga tataattgta aaaaaagaca gaacctttgt
    18301 caatgtataa ctgacaaaga tggagaattt ctatgacttg gaagattatt gctgactctg
    18361 gttgtgatta tcgtcaactg ccaacaccag ctattaacac aacctttgta agtgtcccct
    18421 taaccattca agtagctgat caggtctttg ttgatgacgc cagtctcgat attgaccaaa
    18481 tgatggaaac catgtatgca actgcagaag cttcaaaatc ggcttgtcca agcccagatg
    18541 actatttgcg agcatttgaa ggtgccaaaa acattttcct agtaaccatc acaggtaccc
    18601 tttctggcag tcacaatagt gctcaactag caaagaatat ttatctggaa gaccatcctg
    18661 acactaagat tcatgtgatt gatagtttat ctgctggtgg tgaagttgac ctactcgtag
    18721 aaaaattgaa tgacttgatt gaccagggct tgtcttttga agaagtggtt gaagctatca
    18781 ccgcctatca agaaaaaact aagttgctct ttgtcctagc caaagtcgat aacttggtga
    18841 agaacggccg tttgagcaag cttatcggta cggtcgttgg ccttctcaac attcgtatgg
    18901 tcggaaaagc tagtgaaact ggaactctcg aattgctaca aaaagcaagg ggatcaaaga
    18961 aatcagttca agctgcctat gatgagttag taaaagctgg atatgctggt ggccgtattg
    19021 tcatggccca acgcaataac gaaaaatgtt gtcaacagct ctcagagcga atccgtgaaa
    19081 ccttcccaca agcggatatt aaaattctac caacctctgg tctctgcagt ttctatgcag
    19141 aagagggcgg tttgctgatg ggctatgaaa ttgattaatt gcattcttga caagaggtga
    19201 ccatcatctc ttgttttttt gtggtacaat agagctatga aacattttga tactattgtc
    19261 atcggtgggg gacctgctgg tatgatgtct acgatttcca gtagctttta tggacagaaa
    19321 accctcctca tcgaaaaaaa tcggaaactt ggaaaaaaat tagctgggac tggtggggga
    19381 cgttgcaatg tgaccaacaa tggtagctta gacaacctgc tagctggaat tcctggaaac
    19441 ggacgctttc tttacagtgt tttctcccag ttcgataatc atgacatcat caactttttt
    19501 acagaaaatg gtgttaaact taaggtcgaa gaccacggac gcgtctttcc agccagtgac
    19561 aagtctcgga ctattatcga agctttggaa aagaaaatca ctgaactagg tggtcaagtt
    19621 gctactcaaa tagaaatcgt ttctgttaaa aaagtagatg accagtttgt ccttaagtca
    19681 gcggatcaaa ccttcacttg tgagaaactc attgtcacaa caggtggtaa gtcttatcct
    19741 tcgactggtt cgactggttt tggtcacgag attgctcgcc attttaagca taccatcatc
    19801 gagcttgagg ctgctgaaag tcctttatta acagattttc cacataaagc cttacaaggg
    19861 atttctctgg acgatgtgac cctaagttat ggtaagcatg tcatcactca tgatttactc
    19921 tttacccact ttggtttgtc aggtcctgct gccctacgca tgtctagctt tgtaaacggt
    19981 ggggaggttc tctcactcga tgttttgcct caactttctg agaagaactt ggttacattt
    20041 ctagaagaaa atcgggaaaa atccttgaaa aacgctttaa aaaccttgtt accagaacgc
    20101 ttggccgaat tttttgtaca aggatatcct gaaaaagtca aacagctgac tgaaaaggaa
    20161 cgagaacagc ttgtccagtc cattaaagaa cttaaaattc ctgtaactgg aaaaatgtcc
    20221 cttgcaaagt cctttgttac caagggtgga gtcagtctca aggaaatcaa tcctaaaacc
    20281 cttgaaagta agctggtacc tggcctccac tttgcaggcg aagttatgga tatcaatgcc
    20341 cacacgggtg gctttaacat cacttctgcc ctctgtaccg gctgggtggc gggaagtctg
    20401 cattatgatt aaagattaaa ggttgtgaag aatgaacaga agagaggcag tcgaatttgt
    20461 taacatgtgt atgattaaaa acggagataa ggtcctggtc caagaccgag ttagtcccga
    20521 ctggcctggc attacttttc ctggtggtca tgttgaacgt ggcgaatcct ttgtcgatgc
    20581 tgtcattcgt gaagtgaaag aagaaactgg tctgatcatt tccaaacccc aactctgtgg
    20641 tatcaaaaac tggtatgacg acaaggattg tcgttatgtc gtcctttttt acaagacaga
    20701 acactttact ggtgaactcc agtcttcaga cgaagggaaa gtttggtggg aggactttga
    20761 aaatctttct catctaaaac ttgcaaccga tgatatgtct gatatgcttc gtgtgtttct
    20821 agaagaagat ctcagtgaat tcttttacta caaaaacggt gacgactggc tttatgattt
    20881 gaagtaaaaa atatgctagg aaattcccaa tgtcattaag ttaagaaatt caaatacaat
    20941 tctgtatttg ggtctctttt ttatgtgata aactatagtt aaggaggtat ttcccatgat
    21001 aaaacagata aaagcccact tgaataagag tattcagagt atcattggcc aaaaagttga
    21061 gttcgtcaaa caagatgaac aggcctttac tcgtaaaaga aggttatcac tagaaactat
    21121 gattcgtaca attctgggca tgggaggaaa atcactatca aaagaattac tagatgccag
    21181 actgacagtt tcaaattcag cctttgttca aagacgctat cagataaaac ctgaagcttt
    21241 ctatgcccta tttaaagaat ttacagcacc tattccactt aatactgatt ttccaatatt
    21301 cgctgcagat gggagtgata tctgtattcc tcgaaatccc atggatacag aaacctctat
    21361 ccaaacccaa acggatgtta aatcctataa tctcatacac ataaatgccc tatacgactt
    21421 gacgactgga gtgtatagag atgtctctat tcaagacaaa catgcacaac atgagcgctt
    21481 agctctgatt cagatgacgg aggcttctcc ctttcgagaa agctcttgtt atcatggata
    21541 gaggctatga aagttacaat ctcatggctc attttcaaga aaaaggttgg ctttatatca
    21601 tccgtattcg agatggaaaa caatccatgc cttcctcctt caacttgcca aatacggagt
    21661 gttttgatca aaaagtttct ctaaaattat cacgaaagca aaccaatcag ctcaaaaaac
    21721 tttatcgtga ttttcccaat gactatcatt ttattccaca caattctatt tttgattttc
    21781 ttccagaaac aagtcgaaaa caagatcctg taacactcta tgaacttcct tttcgtatgg
    21841 tgcgtttaga agtggaagaa ggaaaatacg aaactttagt gacgaataca gactattcag
    21901 tccaagaatt aaaaaatctc tacgccagta gatggggcat agagactagt tttcgtgacc
    21961 tgaaatacag tattggcttg gtcaattttc acgccaaaaa gaaggaaggg attctccaag
    22021 aaatctttgc tcgctttaca aattttaact tttgtcgttg ggtaaccttg caagttgcca
    22081 tcgacagtag tcacaaaaaa caaagatata aagtgtgttt ctcagatgcg gcttatgcct
    22141 gccgtttgtt ttttaacggt tccctttctt ccctccagtt gaaaaactac ctcaagaaac
    22201 agttatctat tattcgaccg aatcgaaaat attcaagaaa gataaaagct caatcggtag
    22261 ttgatttcat ctatagagta acataaatct caaaaaatag ggtgaaaaaa cctttatttg
    22321 tcatgcaaaa aaatagaaga tgtgatagag aatcactttg atgatcccaa tcacacctcc
    22381 tattcaagta gttagatcac taacttaatg acattgagga aattcctagc ctattttttc
    22441 tgcatttgtc tgaacgtaag ctgcaatggc atctgacgtg tactgggctg ttccagaacc
    22501 aaacttgtca atgttttcct taaactctgg gttgtagacg taacctttac cgatatgacc
    22561 gaatacctca atagagcagt caaatccata agtgcgaatg gcttgcaaga gcttggctgc
    22621 ttgctcttgg ttttcggttg ctgttgcagg taaaccaact tgaagatttt gtgccaaagt
    22681 ttgaaagact tggttaaagg cggccgtagc ctcgtcttcg tgaccttttt ggcgttcgag
    22741 cgcttgtccc atgacttctt gaccatattt ctctaccgct tcttggtggt atttttgatt
    22801 gtcttgatag ctaaatcccg tgaatttttc ctcaatggtc atttttcttt ctcctttttg
    22861 ttcttgaata gttttttgca aggtggaaat caaggtatcc agatgttgcc tttcgcgagt
    22921 tagatagtcc aactgcctag tcaaatgggg caataaatct gtcctttctt cctttaacag
    22981 ctctgctatt ttctctaaag aaaagcctag atatttgtag taaagaatga cctgaaggcg
    23041 ttccaaatcc tcttgactgt aggttcgata gccgttttcc gactttaagg ggaccaagag
    23101 tcctatcttg tcatagtgat gcagggtctt gacagagaca cctgaaagct gcgcagcttc
    23161 ttttatatgg tacatgattt cctccttaca atgatagtat aacccctccc cttaggtcag
    23221 agtcaagcgt ttttgagaaa attttttaac ttttttgaga aaggtgtgaa aacttgaaaa
    23281 tgattttctt gacagacctt agaaaacatg ataggatagt caagtctatc aatcaaacag
    23341 aaggctattt gacaactcaa gtagcttttt cttattttga aaaaggagat cagagtttaa
    23401 ctatgtcaga aaaatcacaa tgggggtcga aacttggttt tattctagca tctgctggct
    23461 ggccatcggg cttggttccg tttggaagtt tccctacatg actgctgcta atggcggtgg
    23521 aggcttttta ctaatctttc tcatttccac tattttaatc ggtttccctc tcctgctggc
    23581 tgagtttgcc cttggccgta gtgctggcgt ttccgctatc aaaacctttg gaaaactggg
    23641 caagaataac aagtacaact ttatcggttg gattggcgcc tttgccctct ttatcctctt
    23701 atctttttac agtgttatcg gaggatggat tctagtctat ctaggtattg agtttgggaa
    23761 attgttccaa cttggtggaa cgggtgatta tgctcagtta tttacttcaa tcatttcaaa
    23821 tccagccatt gctctaggag ctcaagcgac ctttatccta ttgaatatct tcattgtatc
    23881 acgtggggtt caaaaaggga ttgaaagagc ttcgaaagtc atgattcctc tgctctttat
    23941 catctttgtc gtcatcatcg aacgctctcc cagtttgcca aatgccatgg aaggggttct
    24001 ttacttcctc aaaccagact tttcaaaact gactagcgct ggtcccctct atgctctggg
    24061 acaatctttc tttgccctct cactaggggt tactgtcatg ttgacctatg cttcttactt
    24121 ggacaagaaa accaatctag tccagtcagg aatctccatc gtagccatga atatctcgat
    24181 atccatcatg gcaggtctag ccattttcca agctcggtcc cccttcaata tccagtctga
    24241 agggggaccg agcttgctct ttatcgtctt gcctcaactc tttgacaaga tgccttttgg
    24301 aaccattttc tacgtcctct tcctctttgc gactgtcact tcttctgtcg tgatgctgga
    24361 gatcaatgtg ggcaatatca ccaaccagga taacagcaaa cgtgccaaat ggagtgttat
    24421 tttaggaatt ttgacctttg tctttggcat tccttcagcc ctatcttacg gtgtcatggc
    24481 ggatgttcac atttttggta aggccttctt tgacgctatg gacttcttgg tttccaatct
    24541 cctcatgcca tttggagctc tctacctttc actttttaca ggctatatct ttaaaaaggc
    24601 tcttgcaata gagaaactcc atctcgatga aagagcatgg aaacaaggac tgttccaagt
    24661 ctcgctcttc cttcttcgtt tcgtcattcc aatcatcatc attgtggtct tcattgccca
    24721 atttatgtaa tcaaaaagga cttgagtagt gaactcaggc cctttctttt ttatggatga
    24781 ctaacaatta attctaaatc ttgcccttct aaagtccaag attcaacatc acttagtacg
    24841 ataaagtggc tccctttttg gattggatag ttttttccat caacagtcag ttgaccttgg
    24901 ccagctaaga tactaaacaa actgtaatca gctgtcttct caaaatcaac ttttccagtg
    24961 atttcccact tgtaaactgc gaagaaatca ttagaaacaa gtaaagtgga acgcaaatta
    25021 tctgctttaa cagttacagg acggctattt gctggctcgc caatgttcaa aacatcgatg
    25081 gatttttcaa ggtgaagttc acgcaagttg cccttatcgt cctttcgatc aaagtcatag
    25141 acgcggtaag ttgtatcact agactgttgg gtttcaagaa tcaagatgcc aggaccgata
    25201 gcatgcatgg tgccacttgg tacatagaag aaatctccag ccttgacagg gactttggta
    25261 agcaaggtat cccagttctt gtcctcgatt tgctggcgga gttcttcttt tgacttggca
    25321 ttgtggccgt agataatctc tgaaccttca tccgcagcga tgatgtacca gcattctgtt
    25381 tttccaagtt cgccttcatg ctctagtcca taagcatcgt ctgggtgaac ttgaacgctg
    25441 agccagtcgt tagcatccag aatcttagtc aaaagcggaa atacaggctc aggacgattg
    25501 ccaaacaatt cgcggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
    25561 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
    25621 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
    25681 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
    25741 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
    25801 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
    25861 tcaatgacat ccttgtacca atagaaggac ttcttcttgc tccgtttgaa acttccatga
    25921 ccagcattat ctcgatccac atagataaag ccatagcgct tgttcatttc gcctgttcca
    25981 gctgaaacca gatcgataca accccaagtc gtataaccaa gcaagtcaaa ctccatcttg
    26041 gtaaatggca tctcgcatgg ccttgatgtg ggcctctaag taagtaatcc gatagtcatc
    26101 tgctacataa ccattctcat ccggtgtatc catagcaccg agtccatttt ctacgataat
    26161 actaaactaa aatcaaaaag cattatataa tagtgatatg aaatcaacta aagaagaaat
    26221 ccaaaccatc aaaacacttt taaaagactc tcgtacagct aaatatcata aacgccttca
    26281 aatcgttcta tagtaaaatg aaacaagaac aggacaaatt aatcaggaca gtcaaattaa
    26341 tttatagaaa tattttagca gccaaggtgt actgttatag attcaataca ctatagactg
    26401 taatcaaaca acgatttggc gaaatgtaaa aaaatatgag gagttcggac tcgactctct
    26461 ccttcaagaa acacgtggtg gtcgtaacca tacatatatg acagttgagg aagagaaagc
    26521 ctttcttgct cgccatttga aggctgcaga gacaggagaa tttgttacaa ttgatgcctt
    26581 atttcaggct tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact
    26641 gttgaagcgc catggttggc aaaatattat gccacgtcca gaacatccta agaaagcaga
    26701 cgctcaaacc attgttgcgt ctaaaaataa aatctcaatt caagaaaaca agaaagcgct
    26761 ttaaaaccag tagacgtttt cgtaaggttc gcttgatgta ccaagatgaa gctggtttcg
    26821 gtagaatcag taaactggga tcttgttggt ctccaatagg agtaggtcca catgtccata
    26881 gtcactatat acgagaattt cgctattgtt atggagctgt tgatgcccat acaggcgaat
    26941 catttttctt aatagctggt agatgtaata ctgagtggat gaacgccttt ttagaagagc
    27001 tttcacaagc ttatcaagat gattattttt tactcgttat ggacaatgct atatggcata
    27061 aatcaagtat cttaaagatt ccgactaata ttggctttgc atttattcct ccatacacac
    27121 cagagatgaa ctccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata
    27181 aagcctttca aactttggaa gatgtcatga atcaactcca agatgtcata caaggactgg
    27241 agaaggaggt gataaagtcc atcgttaatc ggaaatggac tagaatgctt tttgaaagca
    27301 gatgagtatt atatgcaatt tctttatata aaaagatcgg attgctccga tctttcaata
    27361 gttcatattc tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat gactacgcga
    27421 cctatttcat acgataaaaa tcaagcacta gaccagcagg tcctttaact aataaggact
    27481 ctgttcccca atcggttaca gttggtccgt gtaaaacctt tataccaagc tcgttcaacc
    27541 gtttgtagtt ctggtctaca tcctcaacct cgatatgaat aatgattcct gactgaaagt
    27601 tttccaaagg aaccaaatga ttttgtgaca acataagaca gtgactgcca atcgtaaact
    27661 gagcaaaacc atcatcagca taatctgcct ttttatccaa gatatgctcc aagtcagcac
    27721 agacttgggg aacatttgaa acgataatat ctaattgatt taaattcatt tactctcctc
    27781 cataaaaaga ccgaattgct ccgatctttt aaagttccgc tctatgaaaa tcaaagaata
    27841 aagtctacaa gtttcatatt tgattttcgg cgagaggaat tatttaattg cgcgtgattg
    27901 caatccttct tcttccaaga agagacggaa tggtacgagt tcttctgctt cgtatttttc
    27961 cttgaaggct ttaatagctt cttctgagtg aagttttgga tccaattcaa gtacttctac
    28021 tggaagtgga cggtgttgag tgatgcgagc atcgatgaca acagttttac cttctttgtt
    28081 caatttaaca gcttctgcaa caactgcatc gatgtcttcg atacggtcaa ctgtgaatcc
    28141 aacagctcct tgagcttccg caattttagc gtagtcagcg tttgtgaagt ctacaccaaa
    28201 caagtgtttg tttgtatctt cgtatttgtt cttgatgaag ccgtactcag catttgagaa
    28261 gacaaggttg ataactggaa ggtcgtattg aacgtttgtg ataacgtctg ggtagcacat
    28321 gttgaatgct ccgtcaccca tgatgttcca tacttggcga tctggattgt ctttcttagc
    28381 agcgatacca ccaggaaggg caatacccat tgtcgcaaag agtggagatg tacgccacat
    28441 gttcttaggt gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac ctacgtcgat
    28501 tgagtagata gcgtcttgat cagcatgttt gttgattgca ttgtaaactt gatacaattg
    28561 caattcaccc tcagttttac cttcgagttt gttcatgtaa tcacgccagt tttggttgtt
    28621 cttaacgttt gcacgccacc atggagttga ttcaactggg tttactttgt caaggatagc
    28681 tttagctgct tgaccagcat caccaaggat tgaagcgtca agggcatgac gtttaccaag
    28741 tttgtaaggg tcgatatcga cttggatgaa tttttcagtg ttcttgaatg cttcgtaaac
    28801 ttcagcaaat gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa agaccacttc
    28861 gttggctggt ttccaaccaa cacggtaagc agaacctgtc aaaccttcat agttccattc
    28921 gaaagcttca aagtttttac cagttgtgat gattggtgct ttgattttac gtgacaattc
    28981 agtaatcact tcaccagctt taacaccacc aaatccagca tagataactg ggcgttcagc
    29041 attgttcaag atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag gagcgatgaa
    29101 tgagcgttcg tatgaacctg aaccgtagta tgagttttcg tcgatttctt ggaaaccgaa
    29161 gtttactgga atttcaacaa cagctggacc ttttttagaa actgcagcac ggcaggcttc
    29221 gtcaattact tttggcaatt gctcagcgta agctacacgt ttgttgtaaa cagcgatacc
    29281 gttgtacatt gggttttggt taagctcttg gaaagcatcc atgttcaatt cgttaactgg
    29341 acgtgatcca aggatcgcta ggaatggagt gttatccata gctgcatcgt aaacaccgtt
    29401 aatcaagtga gtcgcacctg gaccacctga accaactgca accccgattg agccgccgaa
    29461 tttagcttgc ataaccgctg caagagcacc tgtctcttcg tggcgaactt gtaagaagcg
    29521 gatatctttg tcttcagcca aagcgtccat caatgagctg agtgttcctg atgggatacc
    29581 gtagattgta tctacgcccc atgttttcaa tacgttaagc attgctgcag atgcagtaat
    29641 tttcccttga gtcatagtga taactctcct tcaatttttt tagacttgga gaatacgatt
    29701 acatagaatt ggaaacgttc tccaaatttt tactattcca ctgtatcata tttattctga
    29761 cttttctaaa aatctgctca aaactctcta ttctctattc taatacagtt ttgaaagtgc
    29821 tgtcatttct gttttacaac aaagaaatct agtcattact tttagtctat tttactaaag
    29881 tttaacagaa gagaactggt cagaacagat acagaactaa aggccatggc tagacctgcc
    29941 aattctggat tgagagccag tccaacacct gaaaagactc ctgctgctat cggaattccg
    30001 acgacgttgt agataaaggc ccagaaaaga ttgagcagaa tacgatgaaa ggttttctta
    30061 ctcatatcaa aggcacgcac cactcctagg aggttattag ttgtcaacac caaatctgct
    30121 gactcgatgg caatatctgt tccagccccc atggcaattc ccacatctgc tacactgagg
    30181 gcaggagcgt cattaatccc atccccaaca aaggctactt tgccagccgc ttgtagttta
    30241 tggatttcat ggactttttc ttctggcaag acgcctgcaa tgacctcttc aattccgatt
    30301 tgatctgcaa tagcacgcgc cacacctgca ttgtctcctg tcagcatgac tgttttaaga
    30361 ccacgttttt tcaactgact gatggctagc ttggcatttt ccttgggaat atcttgtagt
    30421 gcaagcaagc ctttgatttc attgtccaca gccaagaaca caactgtctt agcttctttt
    30481 tctaattgtt ctagtttttc ttgataaatg ctagaaatat ccatgccatc cagcatttta
    30541 gcatttccaa gcaaaacttg ttttccattg atttgccctg agacaccttt tccgtgcaag
    30601 gcttggaaat tttccacagt gtgaaactca agtccagctt cactcgctcg tttcacaatg
    30661 gcttcagcca atgggtgttg ggaagcttct tctagggagg tagccaatcc aagcacttct
    30721 gtctcgtcgc caataatatc tgtgaccaca ggtttccctt ccgtcaaagt cccggtctta
    30781 tcaaagacaa gagtttgaac tttctggatt tcctgtaaga cagttccatt tttgaggaga
    30841 acccccatct tggcactacg tcctgtcccc accataaggg ctgtcggtgt tgcaagtccc
    30901 aaggcacaag gacaggcgat aatcaaaacc gccactccgt agagaagaga ggacacaaag
    30961 ctagctccaa gcacgaccac actatccctg agcaagacga accaaaccca aaaggtcatg
    31021 attcctaaaa tgacaactac tgggacaaaa atccctgaaa tcttatccgt caagtcctga
    31081 atcggcgcac gacttgtctg agctttcttc acaaaatcta caatctgagc caaaacagtc
    31141 tctgagccaa ctttttctgc tctaaagaca agcgttccac tatgattgat ggttgagcca
    31201 atgacagtat ctccaactgt cttgtccaca ggcagactct cacctgtcac catggattca
    31261 tcaatactag agacaccttc tactacgaca ccatcaacag caatcttttc accgggacgc
    31321 actcgaatca ggtcgcctac cttgacttgt tccaaaggaa cttggacata actatcatca
    31381 ctcaagactt ctgcggtttt agcttgcaag tccagtaatt tctccacagc ttgggacgta
    31441 ttttttctca ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag gataaatcca
    31501 gcactttcga agtaaacagg gagaccagca aagagagcaa ctaggctata gaaataagcc
    31561 actagagttc ccagcgcaac caaggtatcc atgttggcat tgtgcttttt aaaactggcc
    31621 caagcactct ggatatatgg cttacccgca actaacataa taggcgttgt tgctaaaaag
    31681 gttccccaat gcatgacttg atgactaatg ctacctgcca acatcccaat catgagaatc
    31741 acaagaggca cagtaaagat actagtaatc caaaaacgtt gcaggagaga tagagatttt
    31801 cgagtcttct caacgactat atagcttccc ttttgcatct tcatgccaca agaaaattca
    31861 tgtctcccta attcttgagg tgtaaaacga atgactttct cctcatctac gccgattgct
    31921 tccaagatac cttcttcttc aaacagaatt tccttataac agtttgaagg agtagcacga
    31981 tgaaaggtaa tctcagctgg aattcccttt tgaagctgga tatgggctgg atgatagcct
    32041 ttttcagctc ggatacggat tttttgaatg ccattttcta agcttgcttt cacaatttct
    32101 gtcatagtct ccacctactc tacaatcatc ttgccgtgca tcatgttcat accacaagca
    32161 aagccaaact ctccagcctg ttcaggcgtg atttccacta catactcttc ccccattggc
    32221 aggttcgcat gtacaccaaa atctggaaaa acaatttgat ccagacatgg tgaaggatcc
    32281 ttgcggtcaa agacaatgcg ggctggcact gatttcttga ggacaatcaa ctcaggagca
    32341 tagcccccca tgacttccac tcgaatctct tggtatccgt ttttttgctg ggctttttgt
    32401 ccagattttt caggcttttt gaaaaaccaa aacaagataa acgcgataag ggcaatacaa
    32461 ataatggtta caatactatt taacatggcg tctcctttac atacaattac atcttacttc
    32521 tgttacagca cttgatttct tctctgaaat cacagcttcc aagtcttcca agtcagtctg
    32581 agtaaattca cattctacaa tcaagtcagc caacaaattc ctaatcctac gggaacaaac
    32641 cttgtctttg atatcttgga caagtaaatc ccgactttgg tctagagtta aaagggctga
    32701 ataaacaaag gacttgcctt cttttttccg agtcaaacac tctttctcaa ctagacgagc
    32761 caaaagtgtc tgaaccgtgg acttggacca gtcaaaccgc tctgccaaaa ccctaatcaa
    32821 atctgtactg gtctgctccc cctgcatcca aataatcttc atgacctgcc attctgcatc
    32881 tgaaatctgc attaccatac ctccaaaatc tatatttgtc aattacactc aacagtatac
    32941 tctcaaaatc tacatttgtc aattatagaa ataatatttt cttcgaaaaa tagaatttta
    33001 atcatttgaa aaacgatttg cagtcaaata ttactatata aacaataaaa atatgctata
    33061 ctaaagaaaa aagaaaacaa ccactagggg tgcgtaaagc tgagattaac gactgttaga
    33121 tccctctgac tcaatctagg taatgctagc tgatggaagt ggaaatgata atggggacta
    33181 gcagtcttct attgcctttc taaaacagac tagcttgttc ttaagaatac aaacttcagt
    33241 tggttgggag gttttagatg acttatttac ccgttgcttt gaccattgca gggactgacc
    33301 ctagtggtgg tgctggcatt atggcagatt taaagtcatt ccaagcgaga gatgtctatg
    33361 gaatggctgt tgtaaccagt cttgtcgctc aaaataccag aggtgttcag ctaatcgagc
    33421 acgtttctcc tcaaatgttg aaagcccaat tggagagtgt cttttctgat actccacctc
    33481 aggctgtaaa aactggaatg ttggctacta ctgaaatcat ggaaatcatc caaccctatc
    33541 ttaaaaaact ggattgtccc tatgtccttg atcctgttat ggttgctaca agtggagatg
    33601 ccttgattga ctcaaatgct agagactatc tcaaaacaaa cttactacct ctagcaacta
    33661 ttattacgcc aaatcttcct gaagcagaag agattgttgg tttttcaatc catgaccccg
    33721 aagacatgca gcgtgctggt cgcctgattt taaaagaatt tggtcctcag tctgtggtta
    33781 tcaaaggcgg acatctcaaa ggcggtgcta aagatttcct ctttaccaag aatgaacaat
    33841 ttgtctggga aagcccacga attcaaacct gtcacaccca tggtactgga tgtacctttg
    33901 ctgcagtgat tactgctgaa ctagccaagg gcaagagtct ttaccaggca gttgataagg
    33961 ccaaggcctt tatcacaaaa gctattcaag atgcccctca actcggtcat ggttctggtc
    34021 cagtcaacca tacaactttt aaagattaag aaaaaaactc tctagttccc actttaaggg
    34081 aattagagag tttttatact cttcgaaaat ctcttcaaac tacgtcagct tccatctgca
    34141 acctcaaaac actgttttga gctgacttcg tcagtcttat ctaaaacctc aaggcagtac
    34201 tttgagcaac ctgcgactag ctttctagtt tactctttga ttttcattga gtattaatta
    34261 ggaaagaatg tcatgcaact ttgttaaaaa ggcttgcgtt tttgcctcaa tatcttctgc
    34321 ttgcatcaaa tcacgtacaa cagctacacc agctatgcca gtgtccataa gctgatcaat
    34381 attctctgat gtcaagccgc caatagcaac tactggaatg gcaaccgttt ggcaaattgt
    34441 tttcaaggtc gatatcagag taatgggcgc attttccttg gtggtggttg ggaaaatggc
    34501 tcctgtaccc aagtaatctg cacctgattt ctccgcttcc agagctcttt taaccgtttt
    34561 agcggtgaca ccgaggattt tttcaggacc caagactttg cgagctaccg aaactggtaa
    34621 ttcatcatct ccgatatgca gacctgctgc atcaaccgca agacaaacat ccaaccgatc
    34681 atcgattatc aagggtacct gataagcatc tgttatttcc ttgacttgtt ttgccagttg
    34741 ataatattga ttggttgtga gatttttttc tcgcaattgg actatggtaa cccctgaacg
    34801 gcaggccgtc tcaacttttg caagaaagct ttccacggaa tcttgatagc gattggttac
    34861 cagatatagt ctaagtgctt ctctattcat aaacctctcc tttgatggta tctagccaat
    34921 tttcatctct tcttaggatc gaaagctgat tgagtacttg gtaacgaaat tcttccaatc
    34981 ccattccttg aacaactatt ttctcagcag cgatattaag ataagagact gctaagcaag
    35041 aagcttcaaa accagtcttt ccttggctga gaaaaacagc tgttaaggct ccaaccaagt
    35101 ctcctgtccc tgttatccag tctaattcag tacagccatt ctccagtaca gcaacttgat
    35161 tctccgaaac aataaggtcc ttggggccag taactaagaa agacatacca ggataggtct
    35221 gacaccaatc tttcaagact tgaagcaaat cctccgtttc ttgatcttta gcactcgcat
    35281 cgaccccaac gccgtggtgc tttaaaccaa caagacttcg aatttctgac atgtttcctt
    35341 taaggatcgt agggctatag tctaaaaggt ctctgactag tcccttacga atgggcgacg
    35401 ctgatacacc aaccgcatct actaccatcg ggagagaaga ttggtttgca tacgaagctg
    35461 ccatgcggat tgctttttcc ttctcagctg acaaatgccc caaattgatg aagagagcct
    35521 gactttgctt agtaaaatca agaacctcac ggggatcatc tgccatgaca ggtttgcatc
    35581 ccagagccaa aatcccattt gccagcatct cacaagaaat ctcattggtc atacagtgaa
    35641 tgagggaact agagcctata ggaaaaggat ttgtcaatgc ctgcatcatt ctatcctttc
    35701 agcaaagaaa tatccttgca cttttttaaa gaattcctgc ttgattaaaa atctaaatgc
    35761 aataaaggaa atcgctgtac caatcaaggt tgctccgaaa aatcgaggag tgtagataaa
    35821 ccaactaagc ttagcagccg atcctgtaaa gagcaccata acaggatagg aaacaataga
    35881 accaataata cctgttccca caatttctcc caaggcagaa aagtaaaatt ttcgaccgta
    35941 cttataaaag agacctgcta gaagggctcc aaaagtcgct cctgtgagag ctaaaggcgg
    36001 aatcccttga gtcgtcatac ggataaaggc tgtcactgta gccatagcca aggcataaac
    36061 aggtcccatc atgattcccg ctagaatatt gactacactg gacatcggtg ccattccctc
    36121 aatccgaaag ataggtgtaa ggactacatc aagggcaatc atcatagata aaatggtcaa
    36181 tttgtgaact tgtagttggt gctttctcat gtttctattc ttctcctttt tctaaagact
    36241 gtaaatcgct cttccatgtc tggtgttggt aggccatttc ccaaaacttg gcttccatat
    36301 gaacactgat gtggaaggca tctagcattt tttgcttatc tgtctcatca ctttctcgat
    36361 agagctgatt gaccagtgct ccctcctctc tgatctgttg ctctaactca tccgtaatat
    36421 aagtttcaat ccattgttga tagagaggat ttggtgatgg tttaagatta agtgatttgc
    36481 ctatgtcatg gtataaccaa ggacaaggaa gcaagcttgc aaaagctatg gctaagttcg
    36541 gctctgcaaa ttgcctataa atatgagaaa tgtaatgata acaggttgga gcgattggat
    36601 gttgctccat ttcctggtcg ctgatttcca attccttgaa aaattgttgg cgaataaata
    36661 actcaccctc cactaaaccc tgagcatttt gtttcaagag tcttttcatc tcttggtttg
    36721 aagtcttatc agccaaaaga tgatagattt ctgagaaggc cttcagatag taggcatcct
    36781 gaatcaggta atagcggaaa atggcaggtt ctaaattccc ctcttgtaat tgtaaaataa
    36841 agggatgatg aaaggaagcc tgccaagctt tcttggataa ttccatcgca atatctgtaa
    36901 attccataat aactccttta taaaaataga ctggtttgaa gcaataaaaa gaaaagcagg
    36961 tagattaatt ttgttttttt aggaatataa aaagtccgat agctattctt caactgtgca
    37021 tgttcgtcat atccgtgagc agatagagct ctcaggtaaa gatggcgcca cctaaagact
    37081 gtcatcagaa ccttactgta aatcaagggc gaccaaaaat gtagttcttg accacgtaat
    37141 aggcaagctt ctttgaggga cttgatttct tgctgaatga gaggaaaaga attgaatacc
    37201 acaatcaagg cataggacca agagcgtgat agcccctttt gagccaagta caagagaagc
    37261 tcttttagtg aaatagagga aacaaagaca aggccgatac aaactgtcac aaaggccctc
    37321 gttccaagca tgactgcctg tgaagcatct ccgtgtaact gaactgccca gtagttggca
    37381 aaagatggta aaatggcaag tatgatcatc caagctaaca ttttaaatcg acggtaatag
    37441 agcataaaga gaatacaaaa tgcgactacc gaaagattca gagcaatcga aggaatgaaa
    37501 gatgtttcca aggataaaat cagcaagaag agactgataa tcggtgtctg ggttgctact
    37561 ttgaccatac tatctcactt ccccttgggt attgctactc tgagatgtaa gtggtttggt
    37621 aatggtcact tctttcacat gccgaagacc ctgactagtc atctcaatcc aataatcaac
    37681 cacagaaatc aaagggtcta aacgatgact aatgagcaga aaacttcttc cttgattcct
    37741 ctcctccaca atccacttgc aaaaataatg gcaggctcta tcatccaaac ctgcaaaagg
    37801 ttcatctagc aagatcacgg aagccttact ggtcaagatg gtcaagagct gaagaatttt
    37861 ttgctgacca ccacttaatt gatagggact cttatcgact gcctgctcca aatcaaaata
    37921 tcgtaaagct tgaaaaatcc gctgatttct ttcagaatca ggtccatcta attgaagctc
    37981 ctctcgcaga ctgactcgga taaactgctt ctcagcttcc tgaacaacac ccgtcagatc
    38041 acggtacaaa ctctttttct ttttcaggac tgtccccttc catgcaatgc gccccttata
    38101 cttttgaaat tgaagaatag agcgaaagag ggttgatttc ccgacaccat tgtcacccag
    38161 gatacaggaa atcccttgat agaatgtgaa atcagcaatt gaaaagaggg ggcgattacc
    38221 aagctcacca gtcacacggt tcatatggaa tagttccggg ctagaagcaa cttcctttga
    38281 agcaacctgt gtcatctcat aggaagggat ttgaaacact tcccttagtt ttccgtctct
    38341 tagctcaacc atatggtcga tataggcttt atagtcagat aaatcatggt cgcacaaaat
    38401 aactgtcttc ccatcaagag ccaactcttt tagaatctcc aatatctcga ttctgctctt
    38461 gcggtcaata gaagcgaagg gctcatccaa gagatagacc ctaggattca tggcaaagag
    38521 gacagccagc gctgcttttt gcttttcccc acctgatagg tgatgaatgg gacggtgtaa
    38581 gattgcctcg caacgacatt gctggacaac ctctgctatt ttagaatcaa tttcctgaag
    38641 gtgatagccg atattctcca aggtgaaaat cagctcctca aacaagttct ccatggtaaa
    38701 ttgatgattg ggattttgaa agagaatgcc aaccttctgg acacgtgcga tgatagaaag
    38761 ctgactgacc tcgctcccat ctatcaggac ttgaccacta tagggaagag aactgacttg
    38821 ggcaatcatt tgaaagaggc tggattttcc tgaaccactg ctcccaacta acaaggtaaa
    38881 ggcttgcgca tgaaaagtaa aatcaaacgg ctcagagaag attggggact gaatcgctcg
    38941 tagttccaga cccatctatg cttttcctcc agttgcaaac tgatgataga gtttgacaat
    39001 ggcacgaacc aagatggtac agaagaaata aacagaaata aaacgtacca caagcaagga
    39061 aaggacaaac ggaagggaaa aggcgtagta acctaactta atgtattcat agacaaagct
    39121 aacaagcgta atcccaatac tattagcagt tagagagagc caactttcat agcgattctt
    39181 agttacgata aaaccaaatt cacttcccaa accttgaacc aagccagaca aaagagctcc
    39241 tagaccaaat tggctaccat aaaggacttc agcaagcgca gctagcactt ctccaatcgt
    39301 tgcacttccg actctcggaa caaagatggc agcaatgggc gcagccatac accagagacc
    39361 gaagaggatt tcattggcaa aggcctgcaa accaagaggt gttaagagta gactgagaat
    39421 attatacaca tatcctgaac caacgaaaac cccaccaaaa aagatagaca agaaagcaag
    39481 caagataaca tcttttaact gccatttttt caacataaaa aaactccttt ttttaaagaa
    39541 aagtggggca ctcaagaaga ccgacctaaa tactttgtat agcagactga atttagaaca
    39601 gtacacaaga acactaaaat atttctagaa attaatttga attttctaat tgatttgttc
    39661 gcatcttatt tcaatctact atatcatctt catccagttt cgtaaaagaa aaaactctaa
    39721 ttacagatac gaattagagt tcagcttaca agattagaca gttcttttcg acatacgaaa
    39781 aaaacatttc acatttccct tcgccagtct taactgtatc aggttcaatg ggtatcatct
    39841 cagcctaaag caccccaaat gtctttatta tttaattatg tgattattat aacacacatt
    39901 ttatactagt tcaagaaatt gaactggaaa tacagccttg cactcacaaa gacagcagat
    39961 ctttcttttg caaaaaacaa atgacctgtt tgatgaatta gccattcaag ctgaatctgg
    40021 acatagcttt ctggacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag
    40081 gatagatatc tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga
    40141 tattgccgaa atgattgaaa cgccatccat attggtcttt ataatgtctt taatatgttt
    40201 cgtctgtatc ccaccaattg caactaaagg catttgtggc aatagttttc tcatcaattc
    40261 aagaccttca taacctatag caccaccagc atcatctttt gactgggtat caaatacagg
    40321 cccaacacct acataatcta catattcaac ttttgattgt tgaaattctt cttcgtttct
    40381 tatagaaaga ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc
    40441 atcttgacct acatgtacgc catcggcgtc aatttccatt gctaaatcta tatcgtcatt
    40501 aacgataaat ggaacattgt attttttaca aagttcttta atttggatag ctagctcaag
    40561 tttttctaag ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc
    40621 accttttaag gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc
    40681 acaaataaaa tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt
    40741 cctttacatc ttcatctgta atctcgtata aggcatttat aaattcaact ttaaatgtcc
    40801 caggaagatg tccatttgga cgtttttctg ccatttctcc agcgatattg taaactaaca
    40861 ttgctgtttc taatgatttt aattcttgac ctttttccag tccgataaaa cttgctacta
    40921 cagctcctaa taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa
    40981 tcgttaccac ttctccatta acagcaatgg catccacttc acctgttact actattggaa
    41041 tattgaactt ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat
    41101 ctactccttt agatgccaca tctattccta ctaaagaggc aatctcgcca gcatttcctc
    41161 taatcgctgc tagtttataa ttgttgatta gatcatctgc tacttttttt ctatattctc
    41221 ctgctccaca ggctacagga tctaaaactg ctgggacatt atatttctcc gcaattttca
    41281 gagcagcttg gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac
    41341 caccagcata ctttaacaaa tcctctaaat ctgctggaaa ctcactcatg gctggtgagg
    41401 cgcccagtgc tactaatcca tttgctgtga aattttttac tacatcattg gtgatgcaaa
    41461 tgaccaatgg tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt
    41521 tcactttata cgatctactg atttcgattt atctctatct ttcgttaaga aatttttttc
    41581 atttacgttg aatgatttat actcaatgaa aatcaaagag caaactagga ggctaaccgc
    41641 aggttgctca aaacactgct ttgaacctgt agataagact gacgaagtca gctcaaaaca
    41701 ctgttttgag gttgtggcat gagccttctc tagacatcgt aaccaatatc aaaaaaagct
    41761 aattctaaag cgactgcttg attccagcgt tgctgaagtt ctgtcaaatc ttctcgattt
    41821 ttaccgacac gattgagttc gtcaaccaga aattgaaccc actctgcaaa gaaaggacct
    41881 ctgtggagat tgatccattc cgaatgaata tagacttcag gtagagccaa atctttagaa
    41941 ccccagtcta aatagagacc ttctgcaatg accagcataa ccaaaagatg ggcatagtct
    42001 gatgaagcca ctgccgaata cattagatcc tgaaaggctt ttgttacagg gtgcaaagtc
    42061 acttctagat agtcattctc tgctactttt aactctttaa aagccttttg gaaataacca
    42121 tcttcatctg cttcaagaaa gcctagttgc ttggcaaaac gaagcttgga ttcaagttta
    42181 tctgcgtgag ctacgcaggc acccagcatg gataagaagg catcaaagaa gtgataatct
    42241 tgaatcagat agtcctttaa gaccttattc tcaattgtcc ccgcaaaaag ttccttaaca
    42301 aaacgatgat tgattgcagc ctgccaatcc ttctgactgc tttttaataa ttctccaaca
    42361 gtcaaacctg gctgaaatgc atagtcttgt gtttccatat ttacttctcc tctctttact
    42421 tgttagtaat taataaaaca ccaagaaata tcaagcaaaa tcgtaattcc acttgatcct
    42481 tttaaagcac atcgagagca tttgcagaga gctaactaaa caagcctatc cagtttatat
    42541 aaacaaaaaa ctccaattac aatcaagaat tagagttgac ttacaagatt agaccgttca
    42601 tttcaccata cgaaaaaact gttcacattt cccttcgcca gtcttaactg tatcaggttc
    42661 aatgggtatt atctcagcct aaagcacccc aaatgtctct attatttaat tactgaacca
    42721 gtatagcaaa aaatgaaagc cctagcaaga tatttgaccg aaaaatatct ttatatataa
    42781 tatattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac
    42841 tgtcctgatt gatttgtcct attcttattt cattttacta tagttttcga tagcgattta
    42901 ttcttccaat acacgaagaa aaacctccac attcagtgaa ggcaatctgt tttatcaata
    42961 caattttaag tcacgagggt caactgggaa ggttgggttg tatggattgt gacggagctt
    43021 aaagtgtttg acatcttcaa tggtctgagc tccagacaat tgcataactg tcttcaattc
    43081 cgcattcaag tgttcaaaga cttgacgcac accgacacta ccaccgagag ccaagccata
    43141 aataacaggg cgaccaatag ctaccaagtc tgctcctgaa gccaaggctt taaagacgtg
    43201 ttgaccacga cgaacaccag agtcaaagac aatcggcaca cgtctatcaa ctgcttctgc
    43261 cacttcttga agcgagtcaa aggcagctgg tccaccgtcg atttgacgac caccgtggtt
    43321 ggttacccag ataccagaag ctcctgcagc aagtgaacgt tcaacgtcct cacggcattg
    43381 tggtcccttg acatacacag gaagaccaga gtattcagcg ataaattcta catcgcgtgg
    43441 agacaagcgt tgtttagctg atttgtaaac aaagtccatt gatttaccag caccttctgg
    43501 caggtattct tcaacaatcg gcatgccaac tgggaagaca aaaccattac gcttatccac
    43561 ttcacgattc ccccctacag tagcatctgc cgtcaagaca atcgctttat aaccttcagc
    43621 cttcacacgg tccatgatgt ggcggttgat accgtcatcc ttactaaagt aaaattggaa
    43681 ccaatggggt gtcccttgaa gggcttcaga aatctctgga aggtcaacag tagagtaaga
    43741 gctggttgta taaagagaac caaactcatg cacaccacgc gcagtcgcca cttccccctg
    43801 ttcatttgcc aatttatgag ccgcaacagg cgccataatg attggtgaag atagtttttc
    43861 acctgcaaat tcaatctctg tacttggatt ttcaacatcg caaagtgtat gaggaacgat
    43921 gagtttgtgg ttaaaggcgc ggatattctc tcttaaagtg aaagtatctt ccgccccact
    43981 agcgatatag ccaaatgctg ctttaggaat aacttgttgc gccattggct ccaaatcata
    44041 ggtattgatg aagtctacat gaccttctgc attgcttgtt ttgtatgaca taaaatgccc
    44101 tccttgatta agtaagcgtt tgctttttac tacacaacta taataactct tttttcaatc
    44161 attttcaaga gttttgctta aaaaccatct tattttttca tacaatatac tagccctact
    44221 ttccttaaac tctaaacttt agtctatatt aagtgaatcg ttgagatttt ttgctgccag
    44281 gcatttgaac tactttttta tttgctgatt ctatctacta atactataaa aaacaagtga
    44341 ataagacacc agaacatcct ctaataggac ctatggactt atatcagtcc catatatact
    44401 gtttaagcaa gatactatcc tagttgacgc taacttccta tcccacttat taatttttta
    44461 tttatagtga atctgaacaa atcaattggg gaatccaagt caatttctag tactttttga
    44521 acagtttcag cgtactatcg taaaatgaaa taaaacatgc acaaattgct tagggaattt
    44581 aaaccaattt ctaacaatgt cttagaaatc aaagtgtact atttcaactt caatatacta
    44641 cacttcattt tctccttaaa ttcagtctct ttttgaatca aaaaatcctc tggtaagagc
    44701 cagaggataa gaatttattt cattgttggg aagagcaata catcacggat agttgttgta
    44761 tcagtgagga gcatgcagag acggtcgata ccgattccca aaccacctgt tggtggcata
    44821 ccgtattcaa gagcttcaat gtagtcatag tcgattcctg tcgcttcatc atcaccaagt
    44881 tctttggctt tagcttgggc ttcaaaacgg ctaagttggt cgattgggtc gttgagttca
    44941 gtaaaggcat taccgtactc cttagtcatg ataaagagct cgaaacggtc agtaaagcgt
    45001 tggtcttcag gatttttctt agcgagtgga gatacagcta ctggatgtcc atagacaaag
    45061 gttggttgga ttaaagtttc ttcaacaaac tcttcaaaga aggcattgat gatgtgacca
    45121 acctcagtgt agtgtttctc aactggaact ttcttctcag cagcgatagc tttagcttct
    45181 tctaaagtca tgtcttgcca gaaatcgaca ccagtaattt ctctgatagc atccaccata
    45241 tgaacacgct taaatggttc gttaatcttg atttcagtac cttggtagtt gactgggcca
    45301 tcgcccttaa ctgatttagc agcgtgttgg ataatgcctt ccgtcaagtc catgatgtct
    45361 tggaagtctg cataagcttg gtaaacttcg atagaagtaa actcagggtt atgagtagcg
    45421 tccattcctt cgttacggaa gatacggcca atttcataga cacgttccat accacccacg
    45481 ataaggcgtt ttaagtgaag ctcagtcgcg atacgaagca ccatgtcaat gttttgggca
    45541 ttgtggtggg tgataaatgg acgggcagca gcaccaccgg cttcattatg aagaacaggt
    45601 gtttccactt caaggaatcc tttttggtca aggtaacgac ggatttcaga gatgattttt
    45661 gaacgagtga caaagcgttc aaagctttca cggttagaaa tcaagtcaag gtaacgttta
    45721 cggtaaattg tttcaacgtc tgtcaaacca tggaatttct caggaagagg acgaagagcc
    45781 ttagacaagt gtgtgatgtg ggttgccttg atagagagtt ctcccatatc cgtacgcatc
    45841 acttcacctt cgacaccaag gaagtcacca aggtctgctt ttttgaagat ttcgtagttt
    45901 tcttcaccga cagcatcctt acgaacgtag atctgaatct ggccttcgcg gtcttgaagg
    45961 tgggcaaaac caacttttcc tttaccacgt ttggttacca agcgtcctgc gatagtagct
    46021 gtttcgtttt tatcgtgtaa ttgttcttta tcgaggttgg catatttatc ttttaattct
    46081 tgtgaatttg cagtacgttc aaaacgtttt ccgaaaggat cgattccttg ttcgcggagc
    46141 gcagccattt tttcacggcg aacgatctgc tggtcattta gttcttccat atgttctgta
    46201 gacatgggat cctcctagtt ttactcaaaa ttgaatacga tgagtcattt ttttcgatac
    46261 tcccatttta tcataaataa gcaagaaatt cacggataat ctttcaaaac taaaaagaat
    46321 ttgacgccaa gatcactgag ccaaatcact gaaaagactg ggataagcaa gaaattccaa
    46381 aatctcagaa aaggaacgac tgctgagact tattttgaaa agaatcatcc agaaattaaa
    46441 ctccaaaaat atgaccaata cagtgactct taccaagctc ttcttgacgg acgtggagat
    46501 gccttctcta ctgacaatac tgaagttcta gcttgggcgc ttgaaaataa aggatttgaa
    46561 gtaggaatta cttccctcgg taatccagat accattgcgg cagcagttca aaaaggcaac
    46621 caagaattgc tagacttcat caataaagat attgaaaaat taggtaagga aaacttcttc
    46681 cacaaggcct atgaaaaaac actccaccca acctacggtg acgctgctaa ggcagatgac
    46741 ctagttgttg aaggcggaaa agttgactag tcattaactc ttaaaagggg ctggatttta
    46801 agctccaatc cctttttaag attttaccta taacatcctg agtctatcta agatgttcaa
    46861 tctgaacaca gtgtacatac tttatcttct attgcatata ctttatcaca taagatacga
    46921 atatcctctt cactatgact agcaatcaaa attgttgtcc ctttttcact agagagcttt
    46981 ctaaacaatg ttctcatatt ttctacactt gatttatcca aggcattcat aggttcatct
    47041 agtaaaagaa tagagggatt ctccataatt gcttgagcaa tccctagctt tttcctcata
    47101 cctagcgaat aagttttaac tttctggtct ttttgctcat atagaccaac tattttcagt
    47161 gtatcattga tttcctgatt accaactact cctcgtatgc ttgccaaata ttgtaaattc
    47221 ttaaagccac tataataatt tataaaacca ggttcttcaa tcaaagctcc caaattagct
    47281 ggaatttttc tctcaggaac aatattttcc ccattgatta acacttctcc ataagacgga
    47341 ctatataaac cagctattaa tttaaacaat acacttttcc ctgagccatt cgcaccagta
    47401 attcctataa tttccccctg tttacaacta aagttaaggt tttgaaaaac acatgttttt
    47461 tttaatttca actcaatatt ttttaatgta attatttcat tcattctata aacctcctct
    47521 tttgacgagt gaaatagaaa atgcttttaa aaagaaagac taaaaatagc aactgaagaa
    47581 ataaatctcg tcctatatct ccattccctc gattcaaaat ataaaataga taattagttc
    47641 gatttcctac aaatagacca ccaaacacaa tcatgagtaa aaagaaacta acgcaagcaa
    47701 agttcatttg tacattcgct cctagtgcgt ataacataaa gcaaagcaag gatagcacac
    47761 aagcattcaa agaatcaact ataaacaaaa ctcctatatc ccagtttggt aactgtaaca
    47821 taaattgaat cactagaact tttaccatga ttaaaataag tccataaaga aaacaggtcc
    47881 aaatctgata cctaatccag agcttaatag aagaaaatcg aatcacttcc agaaagaaat
    47941 cggatgctct tctacgatat acaactacta gaaaaaatgt atgaataata aaccaatgaa
    48001 gcaaccatat agataagact aaaaaagagt tttgactcag attaggccct tttaaaattt
    48061 ctataacaag tctatcattt ccttctaacc aataccataa tcctaaacaa atcaatatcc
    48121 aaaaaagaac ataaccccaa aagtacttgg catagattat ctgattcaac ctccacatgt
    48181 gactacttaa ctttcccatt tccaactttt acactctcct ccagtttcta tgaacagaaa
    48241 atacagtcaa tggaattatg atagatagta atgtaagcca ataaatcaat gcatacggat
    48301 tggaatttac catatactga aaaattggca ataatccaat tatcccattg ttcaactgat
    48361 aaatccagaa taaggattct acaaataaaa aagtaaacag aaatactaag ctcatgtttg
    48421 attttttaaa ccaagaaaaa ctgctaatag taagtaagga taaaaagaaa tagtatgcta
    48481 tataagagaa aaaaaatcct ataaagaaac tagcattgtt tgcaatactt ataccataaa
    48541 attctcttaa aaaatcaacc tcctttatct ccaaagagaa gctaaaacca ttactaaatg
    48601 caattagaaa aatcaataaa aataaagtcg ccgtccaaat ccccgtacta agagctgcta
    48661 atttgaaact aaaactggta aagtgcttaa ttgatttcag acgaatgcga cactccaacc
    48721 tattaaaata gttattcatc aaatgaaaaa agaacaatat atatgtgaac ggaaagcaat
    48781 atactccagt cgtcatatct tgaagtaaaa ctaagatcca ttctaataca tttggatgga
    48841 ttgaatattg gcgacagcgc aataaatata ctgtactaga taaaacacag gatagcagta
    48901 atataaaata aaccaatact gctaagaaat cttttttata aaattgaaca aattgtttca
    48961 ttatacatag tcctctgaat gtagaaaaaa tgtaccataa acaaccaaac aactaacaaa
    49021 taaaataaaa gcaagatgcc cactaactaa ggaaagactg atatctttct gatatcccaa
    49081 agctagcgtt gtcacaggtt ctaagtaaga tagccctaaa atagcccata aaataccacc
    49141 aaccatcata taggcaactg ggatgaaaat agctcctaat tttttcttca ctagcaaagc
    49201 actagctagt ccaaaaatag agaacacagc gccccaaact ccataccaga gagtcgtcac
    49261 aagactatag agaaactgat tagaatcaaa taattctttt aaggcaccac tataatctcc
    49321 aatataaatt tcctgataag gagtcactaa aagattaatt cctaataata ataaataggg
    49381 gagaaaaaag actagaaaag aagaaataat tgcagtacta cctacaatag ctagatacct
    49441 ctttttagaa attcggcaca attgtgctgt tagaaaataa ctctcagcat cctctattat
    49501 ctgactagaa tagggcagtg tacagataag tgcagctact aggctaatcg gtgaaaatcc
    49561 tcgaatagaa gaagcggcaa aaaaaatcga taaaacttca attttataaa taccattgaa
    49621 agcaaggaaa tttcctaaac tcatgcaaag aagggtcaaa aataaagaca tataaaaccg
    49681 aggtgattga acgactcgta caagattaca aatgaaaaat tccatcctta ctcctcctta
    49741 taataaaaat agggtgtagc attctttttt catgctacac ccacaatcaa ccatctttaa
    49801 ggcttactct gacaagtaag ttaataagaa tctggactcc aagaacctga agtatgaatt
    49861 cttacatgat ttccaaattg tggcgccata gctaatctag taccagaacc aatataattg
    49921 tcaccacctc cattatagta catgacaatc ctagagccag accccaatga atataccggg
    49981 gtaatatctg acccactata ggcgctacga atagaggtat ttaacctttt accgccacca
    50041 gtgctgtcac tattattaat tccagcagag gcgttttctt tctcaagctc actagttgta
    50101 tccgaacccc aacgcggcaa cgttaaatca taatttccaa tctgtctagc taaaactgta
    50161 gggagaaaca aactagatgc aattgtaact acgcaaaaaa ggaatatatt tttcttcttt
    50221 tcatgacatc gtcctcctaa gaagtgataa acaagatagt taattgatca atttgataca
    50281 tattacattt tcattatatc aataaaagaa agcgttgtca attatttcat ttaaaatatt
    50341 gtcatatttt aaatgaaatg gtaaaagagg ctcggtagcc tcgtctctct ttatcttact
    50401 gacctaacct tcttgccaat tttcttggtc ttctttaaag cgttttagaa gatcaaggcc
    50461 ctctggcgtg atgtaacctt cttcttgggc tagatggata agctcgctat agtttgaaag
    50521 cgtcacaagt ttaacaccag catctgcaaa gttcttatct gcttttggca attggtagct
    50581 gaaaatcgct acaactccaa gcacatctgc tccttctcgc ttggctgctg ctacagcttc
    50641 aagaactgaa ccacccgttg aaataaggtc ttcaaccact accatttttt gaccttgagc
    50701 tacgcgacct tcgatttgat taccagctcc gtggtctttt ggtttgctac ggatgtaggc
    50761 aaaaggcaag tccatcttat cagcaataat ggctccgtgt ggaatccctg ctgttgcagt
    50821 tcctgcaatc acttctactt caggaaaggc ttctttgata gcttccacaa aaccattttc
    50881 aattagggta cgagtttctg gataggctag tgtcacacga ttatcagtgt aaatcggtga
    50941 cttgatacca gatgcccaag tgaagggttc ctctggtttg aggtaaacgg cttggatttt
    51001 caagaggtgg ctagcgatat ctttagcaag tgtcatggta ttctcctttt atttttctaa
    51061 tctagttctt taattccagt cctgtgtcca ttcatccttg atggcatgat aagctgcaac
    51121 aggatcctca gcttgggtaa tgggacgtcc cactacgata tagtcactgc cgatttgata
    51181 ggcatcagca ggtgtcatga ctcgtttttg atctccaact gcaacaccag ctggacgaat
    51241 ccctggtgtc agacagataa aatctggatt ggtagcctgc ttgatgactt gtacttcctg
    51301 agccgagcaa acaacaccat ccaagccagc ttcagctgtc ttcttggcat agtgaatcac
    51361 agactcttgc agactggttt ggatattttg aaactcctgc atctgagctt ctgacgttga
    51421 tgtgagctgc gttacagcga tcaatttggc ttgactccca agaccttcac gcgccgcctt
    51481 catcatctct acaccaccag ccgcatggac attagtcata tcgacaccaa gctgagacaa
    51541 gaccttcatg gctgacttga ctgtattagg aatgtcatga agtttgagat ccaaaaagac
    51601 actatgaccc aaacctttta agtaggacac aatctcaggc cccgctgcgt aataaagctc
    51661 catccctacc ttgagataaa ggctttcttc tgctgggaaa agagctaaaa attccttgac
    51721 cgcctcaaaa ctaggaaaat caagagcaat gattggacga tgttctcgca taggtttctc
    51781 cttttgcctt tactagtgag agagtctggc caacagaagc cacgaaaaaa ggaacctgcc
    51841 aacagcaagg ttccacgaaa aatgggtagt ctccaccctt tcaccgtcta accttagctg
    51901 cctctctgga ctgctttaaa ggttttttac tattctatta tttctactag cacttgtcaa
    51961 gtaaaaacag ctaaatccat gttgactgct attgaacacc tcacaagact ctttccaaaa
    52021 gaatagttaa agactttcac ttcggacaga gaaaaagagt ttgcttgtta ccctttaatt
    52081 gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca aaggggaagt
    52141 aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg gcaacaatta
    52201 ccgaaaaaat ccttaatgat gctttgctag cttattaatc accgtcccca aaaatacttg
    52261 gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg cattttttat
    52321 tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag cactattgtt
    52381 atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc tgtagaattg
    52441 ctgtcaaaaa gatcagttca ttttttcctt cccacttgtg tttataatca ttaaaataac
    52501 tcaattaaga aattttcttt ttcctaatag ttatcgtaat taaagttaat agaagaacaa
    52561 tccaaataag tagtgttaga ttaggaatta gagttttatt ccatgaaaat tcctcccatt
    52621 ttgtgaaaaa cttagtaaat agtcccataa aactataatc tgttatcttc gcaactgtct
    52681 tatccaaacc agatagcatc ggtaagaaag caactaaaat catagcagga agactgataa
    52741 cctgagctac tacttggctc ttcgcggtta aacctatcaa taaatagaat aaaatgatgg
    52801 ataaagaggt tagaagaacg attgtaatat aattaaaagt atgtacaatt gtaactccta
    52861 aaataagagg agtagttccc ataatcacaa aagttagcaa aaaaggaaga aacatagttg
    52921 ataaaatgta ttcggagcct ttaacaccac tcaacagaag agtttgtaaa ttgtactttt
    52981 ctttctcttc agacaagata atagttatag gacttccaac agccaaagcc aaagaaaaag
    53041 gtaaacacat catcaaaaga actaatgcct gttgatcgtt gaccttcccc tgtgtttcca
    53101 taagatattt ataaaaatat gtgaaagcaa aaggcactaa aacttgcaat aaaatactct
    53161 tattggaaag gatgatttga caacgcaacc ataccaaagc cagaaaccgt ttaagcattt
    53221 agctttcctc ctgttaatgt gataaaaata tcttctaaag taggctcaca tgaatgaatt
    53281 gaaaaaatat tttccagatc agcctgagat acctgttcta gtgatgtaaa atcaaaagtt
    53341 atctgattcc cattataatc tgtaacctta atctttttat ctttattata tctttgaatg
    53401 agttcagaag gagctccttg ctcaactaat ttccctttat ttaataaggc aacataatca
    53461 cataaaagac ttgcttcatt catatcatga gtcgttagaa aaatcgttgt ccctgctgtt
    53521 ttcaattcta aaattaactc atgaattgtt cgagaagttg tgggatctag acctgaggtc
    53581 ggttcatcca gaaagagtac agcgggtttg ttgataagag ctcgtgctaa aagcattcgt
    53641 tgcctcattc cagtggataa ttttcctgct accatcttgc gactatcata taatcctact
    53701 cgctttaaca aattatcaac acgtgattta ctaatattat aaaatttact ataaaaaaga
    53761 agattgttat acagagacat tttctcataa aatccacttg tatcgctaac caatccaatt
    53821 ctctttaatt caccgcttgt taaattttga gatttttgtc ccaaaataat agattgtcct
    53881 ttatcggcaa ggagctgccc agtcagaata ttaatcgttg tggtctttcc agaaccagat
    53941 ggtcctaaaa atccaaaaat ctgaccttct ttaacagtga aacttatatc atttaaagct
    54001 attttatcac caaaactttt tgataaatgg ctaacttcaa tcatactcat tgcccctcct
    54061 ttatattcta catttttact taacatctat ttacttagct ttatcaaata aacgtcttaa
    54121 aaaaaacaat aacattaagc atataaccgt tagcaagatt gtttcaatat tattgataat
    54181 atgatacatt ctcaagcagt ataaaataat tatatatatg caaatgctca ttatacctat
    54241 ttttttaaac atactaagcc tccttgctaa ataataaagt tatataataa ctaagacaca
    54301 ctatacctaa cataataaat atccacagca ttaaaaatat tatcatacta ataaaaatat
    54361 ccactggtaa ctgaataaat gttctaaaat taacaagcaa aaataaaatc tcaaacgatg
    54421 aaaaaagcca tactatattt tccaatgatg tttgaatatt tttattgtag taagcataat
    54481 atatagcaaa aataataccc aagaacaata ctattaattg tgtttctata acagtgaact
    54541 gcccaatagc agataaaaaa gctactcctc ctgataataa gcaaaaacaa actgaacgaa
    54601 taaatgtttt cgctctaata ttgttatctt tcactttatt atttttttta caaattggac
    54661 attctccgtt ttccagaaca tatttttctt gacttagagc atgatttctc atattataaa
    54721 cgtaagcgtt atctattagg atttcattat aacatcccag aaatatttta attattaaat
    54781 tagtcattat ccctcccaaa atagcaggca tctctggtgt agtcggccac tttgtcttat
    54841 cagataaagt gtacttattt atatctttgt ttatattccg acaagcaaag caagaaccga
    54901 tggtagggat atatatatta tcaataataa gatagcatcc attaaaccct cctgatatgt
    54961 aggatatctt atgcgataca gcaaattgat tgacaatttt tataatatca atgggcgtat
    55021 caattgcttt aacgataaaa tctatactcc catattccgc aacaatgttt tctaattctt
    55081 ctactgaaga aactttaata gaaataggta ctacctgaac atctgaatta tacttgtgta
    55141 ttttttgaga aagaacatta atcttctcct taccaacatc cgactctgta taaagaattt
    55201 gcctatttaa atttgatggt tctattatat cgtaatcagc gacaataagt ttcctcactc
    55261 catacatact tagacttaga gatatataac atcctaaggc tccggctcct aatactaata
    55321 ctgttttatt ctgtatttta ttatactctt cattataaaa taacgaatag taacctttag
    55381 ttctagaata tctactatca atatctatct catccgaaat taaaatttgt tcatttaata
    55441 gttcaaatgt tagtttacta cctaatactt cttctatctc taatagttcc ttacaactat
    55501 taaatagatc gttgataaat tcttgcgaaa tttgaggttc tatagctatt tcccgcatac
    55561 tccgaccacg caaatacatt ataccttctt ttttataagc aaaaacataa ctatttacgt
    55621 agaacatatt tcgtccttcc tctcatatat aatatagaaa gcagtataga aacaactacc
    55681 cctcctatac tacgaacaat aatattaggt gtcaaaaatt gtaatagttg actcaaaggg
    55741 aaataaataa taacaaatgc tattaaaagt tgaactatat attgaaaatt caagttatta
    55801 ttgttagaat tcaagtatct taaaataata ccactatcat actgaaaaaa aggaattgaa
    55861 ttaataaaaa tcatacctaa gttaatgata aaaaataaga gtccaagcaa tttatacgat
    55921 gtgaacaata aaacaagtaa acctgtaagt gataaaatcg aatttgaagc aattcctgct
    55981 aacataattt tcaaaaattg ttttttattt tttaggaatt gcaccccact taaatctaca
    56041 aaaaaagcca aattaaacaa aagtagcatt attccacaat ttgggatctc aatttgataa
    56101 ttattagcaa ttattgcatg actaaattca tgtatcgttg cagatataat aacaacaagc
    56161 aaccaaaata aaagaatgtt tagcgttatt ggaaagtttt ggaaattagt caaaatatcc
    56221 gccctataaa tatacataat aaaacattgc aaaataagag ccaatgggaa aataccaaat
    56281 aggatttttt caaaattctt attaaatctt ttatagttta atttttcaga taatgttata
    56341 ttaaagtccc aagatatttt aaaaatattt atcttttttc gtgatttcat agaatctata
    56401 agtcccattt tactaagaac aatataaaat cttaaataat atttcttccc tactaacact
    56461 aataagtccg atatggtaaa ttcttgacct attagttgct ctaaccattt tttttcctgt
    56521 ttcccaacta atacatgttt cttactggat ggtatatata gatgatactg tccctcataa
    56581 ggagtaggta atatcttaat cttatcaaca attctcataa caaacctaac atttaataaa
    56641 taaaagaggg gctaagtaaa acatactcta gtccctcagt ccgcaatcaa taaaataatg
    56701 actaattcta ttaatctctt gctgcaagac taatacggaa aattcaaatg actgtctaaa
    56761 atgaaattga aaaagcttga tattagtaag tgaacaaact tcaacaacca gcaagagcaa
    56821 ggattgctaa accaaatccg atacctgttg caagtccagc tgaaaaatca ctaactggta
    56881 ctgaaatttc ttcaatttcc tcaaataaaa agttatcttg catgattatc actccctatc
    56941 tttttaacaa caggctactc caattaagag aactacccca gttccaagta aaactccccc
    57001 ccaaaattca ccatctgtag gggctacgat ttcttcaatt tcttcaaata agaatacttc
    57061 atctgacata tgtgttacct tcttcataaa aaattttttt gtaatcgatt acattgcaaa
    57121 tataacataa agaaaaacag atgtcaaata ttaaacgtaa aaacatggtc actaaataac
    57181 tataagagaa aaagtaaacc tagcgacgcg atgagcgctg ggtcgtttgg tttcgattgc
    57241 tctcttcctc ttgttttttc tgttcttctt cttgtttttt ctcagcttcc ttggcctctt
    57301 gtttggcttt ttcctcagcc tccataatca atttatccgc cacagtgtaa ctgtaaattc
    57361 cagcttccat gtcgaccaca ctcggttctg acaattgtgg cttaatctta ctgtaatatg
    57421 gcagtttctt actcatttca gatagaggaa ccaagacttc gtccgaatca ttcatggtca
    57481 atcgaattaa atcggatgtc accttgcttg gggctaattc caccttttgg atagccgcct
    57541 tgagttctgg gctaatttga gcaagttctg agacaaaaac cttgatttgt tcactatcat
    57601 taaagagaac tgataaataa gtttctggta aactgttcag actcacagaa ctagtctcaa
    57661 gctgaccact ggaaagaata ggataatgat tttcaccaga aatatagtag gccacaatat
    57721 catattcctt gaccttaata gtgaacttag ttggaaattg atagacaagt tgagctgatt
    57781 caacccaata gttagactta atctgctttt catattttgc cttgtctagc agaaggttaa
    57841 tcgtataatc cgaatcctga atgcctgaag cctgtcgaat atcatcagct gtagtttgca
    57901 ccgttccctc aacacgaata tctttcatgg tcgcataagg actgagcaag taggcagaga
    57961 caatcaataa aagcagactt ggaaataaaa tcgtgaaggc tcgcaagata tggataccag
    58021 gaatctttgc tttggctggt ttttcctttg tagccttttt agcaagcttt ttatcctgtt
    58081 cctccttctc tttagactct ggttcttctt tctcttcttt ctctttgtca gcctctgagg
    58141 atgctacttt ttcttcagac tcttccttag ctgattctga atcttcctgg tctgtttcac
    58201 tctcctggtc ctgtttatcc tctgacttct cagattcttc tcccattcga gcttgtcttt
    58261 ccttttcctt ctcctcagct agagccgcct cttcttcagc cttctttttt agatattctt
    58321 ggtttcgttt ctgccattct gataactctt tcaattcttc gagggtttct ttgtcctcat
    58381 ttttcttatc ttttgacatt tactttcctt atgataaatc ttttttcaac aattgataaa
    58441 aatctgctag agatttcaat tccttagaag ctttcatctt agcttggtaa tcttccttgt
    58501 gacttagtaa gtgagaaagc ttctcttcca aactatccaa ggtcaaatcg ctttcttgaa
    58561 ggtcttctgc atagcctttt tttacaaagt aagctgcatt ttcaagctgg tcaccacgac
    58621 tagcttcacg accaagcggc acaatgacat gcaattttgc tatcgccaag agctcaaaaa
    58681 tcgtattggc accacctcgt gtcacaacaa tatcagccaa ttccatcaag ggttgataga
    58741 gatcggtcac atagtcaaca cgaaaaagat tttggctcaa ctcattcagg ctagaatctc
    58801 cagttagatt gataatattg tagcgctctg ttagttcttt cttatggtct gtcaccaatt
    58861 ggttaaagac acgagcacct gcagaaccgc caacaaacaa tacagtcggc aatttatgat
    58921 taaagtggct ttgaatatcc accaattcat ctggttctgg atttttttga tctgaaacct
    58981 tggtcactgc tcccacatgc tcaaccttag acaaactcga agcttgctca aaggttgaat
    59041 acatcttagt cgcaaattta taggcgattt tattggccaa gcccatagac aggtcagatt
    59101 cgtgaataaa gacaggcact cctgacacac gcgcagcgat aacaggcggt actgagacaa
    59161 agcctccctt tgaaaaaagg gtctgtggac gaagtcgcaa catgataaag agcgattgga
    59221 cgattcccca gccaactttg aagacgtcca gcatattttg ccaagagaaa tagcgacgca
    59281 atttcccagt cgcaatggag tggaaagtga catccaaacc tgacttaagg atttcttggt
    59341 gttcgatacc acgcttgtcc ccgatatagt ggacttccca accatcttcg atgaacttgg
    59401 gcattaacaa aagattgagg gtaacgtgtc caaccgtccc cccacctgta aagacaattt
    59461 ttttcatatt ttattctttt aactccgcta ctgtgtcgat aaagaggtcg ccacgtactt
    59521 caaagttagc atacatatcc cagctggcat tggcaggact aagaagaacc acatctcctt
    59581 gagtcgcaag ttcataggcc ttgcgggtcg catctgcaat atctgtcgcc tccacataag
    59641 cgacaccagc cttgtctgct gcccgtttga cacgttctgc agattgaccc aggatgacca
    59701 tcttcttgag tccagtaatg tctggcacca attcgtcaaa ctcattgcca cggtccaaac
    59761 cacctgcaat caagacgacc ttgctgttgt caaatcctga taaggctttt tgagtagcca
    59821 agatattagt tgatttactg tcgttataga atttaacacc cttgatgtca tccacaaact
    59881 ggagacggtg tttgacacca ccgaaggctg aaagagtttc cttgatggtt tgattgtcca
    59941 caccacgaag cttggctaca gcaatagtcg caagggcatt ttccacattg tggctacctg
    60001 gaacaccgat ttcattcact gccatgacta cttcaccacg gaagtagagt tgaccatctt
    60061 ccagataagc tccatcaacc ttttcaagtg ttgaaaatgg tacaacagtg gcttctgtct
    60121 tggaagccaa gtcttttgcc aagtcttgat taaagttcaa gacaaggaaa tcagctgctg
    60181 tcatcttgtt ctggatattc cacttggctg ctacatattc ctcaaataat ccatgataat
    60241 cgatatgagt tggcatgagg ttggtaataa ccgcaatctc tggatggaat tcttgaacac
    60301 ccatgagttg gaaagaagaa agttccataa caagcgtgtc cttatctgat gctatttgag
    60361 caacctgact ggcaggatag ccgatattcc ctgataaaag accatgttgc ccagcagcag
    60421 tcaaaacttc cccaatcata gtcgttgtgg ttgtcttacc gttcgatcct gtgataccaa
    60481 taatcggtgc ttctgaaatc aaataagcca attccacctc agtcaagact ggaattccct
    60541 tggccaaagc cttttcaatc atgggattgt tgtaggggat acctggattt ttcaccataa
    60601 gggcaaactc ttcatccaag agttccaaag gatggccacc tgtaatgacc ttgatccctt
    60661 cttccagcaa actttgggca gctggattgt cctcgaaagg tttcccatca tttactgtca
    60721 caatggtacc tagcttgtcc aacaaacgag ctgcagattc accagacttg gccaaaccta
    60781 aaacaaggac tttcttattt ttaaattgat ctattacttt catgtctcga actccatttc
    60841 tactcctact attttaccat ttttatggaa ataaaaaagc cacaaagtgt gtttgtgact
    60901 ctttcttcta actgaatctt accatatcat ctatgtgata aatcggtaac tcgaatgacc
    60961 tgatccactt gctcccaaat cagaggatta tgggtcgcaa taataatggt ccgattcgga
    61021 ttttttaaag attctaggat ggaaagtaat tcctcagagt ttttggggtc taaggaagcg
    61081 gttggttcat ctgcaaggat caaaggtgga tcctttaaaa ttatcttcgc tagtgcaaca
    61141 cgttgtgctt ctcctcctga taactcaaat ataggttgct tcaaatccaa ataagagagg
    61201 tttacacggt ttagagcttg tttcatcaaa gagattttct ctttttcctt caacttttta
    61261 ccaactaaac ccagattgag attctctttg acggtttggc tttcaattaa gccaaaatct
    61321 tgaaataagt atcctaagta atctctaaag aaaacagaag gcttaatgtc cttaagagaa
    61381 gtgccatcat atatgatttg ccctttgtca tatggctcta atcgtccaat catattcaag
    61441 agtgttgtct taccacagcc acttgtaccg attaaggcat aaattttccc accttcaaaa
    61501 tgaagattcg tatctgaaaa tagctgacgg cttccaaatt ttttagatat attctttagt
    61561 tcaatcatcc tattttcctt tcataattgt catagaaaca cgagattctt tctgcgcttg
    61621 acggtaaagc gtcaaaactg cactagctag aaagaccaat aaagtgagta agccaatcac
    61681 caagtctcga ctgcttaaaa taaagagact agcaccaaat acaaaactgg caaattggct
    61741 aaccatatac tgagcatgtg tttcaaaaaa tcgtaaacct gaaattcgtt taatcaagat
    61801 atctcggcgg aattgctcga aatatagaag attgacagaa taaaagagta acaaggaact
    61861 ggctattcca acaatagctc ctaagattaa agttgctgtt tcagtttgaa cttcattata
    61921 acgagttaga taaacacttc ttccttcttt aagataggat acttgctcat aaattccagc
    61981 tttcttcaag agttctagcc cactctcata tcctttgata aagagttgtt ttccagcatt
    62041 gatagaccaa ctagataagg atataaaact atcacctgta gaagtcggcg tgaatactac
    62101 taaaatcgga tcagtcaaat actgagtgga tacgggattc tcaccgttat tataaacaaa
    62161 ccgcttttct cccattgaaa gataactaac gtgcgctttc atctcataat ccaaaggagc
    62221 acttgcctcc tcaccagatt ttccataata actcaatctt tcttcaaaaa ctttcttaag
    62281 ttctgcttct cgagagcgca aatgttctgg gagcaagagg ataaactcac ctttttggag
    62341 atgggctaac ttctgtttgg tctcagcatc taccacgacc ttttccttgt ccaaataact
    62401 gggactaaca tagagcgtat tagcatctgg actataggta tccagtgtct ctccctgttc
    62461 attttttcct tgtggattgg caaaatggag cagattatcc tttacataaa gagcttgttc
    62521 ttcttcgatt gcttccttgg caaaggcata ccacttgctc tgattttctg tatcttttcc
    62581 tctatcacct aagccaaaag aaatttgata atagtctgct ctatcctgcc atgcttgttt
    62641 tgaaatttca agttctttca atcgttggta agacgtcaaa cctgtcttaa cagcgtatcc
    62701 tactgtaaag acagcaacca actgacacaa tagggttaaa atcatcaggc gtttaagggg
    62761 taatctcccc ttaataacgg gaactaatgc tttgtaactc aaactcatta ggtaaaggag
    62821 cattagtaaa attgaaatcg ccaataaaaa caacagatag aaactaatcc caaaaccata
    62881 ggtggctaac aagataggat aaaacaaacc ttgactaaaa agaacgactc ccccacctag
    62941 gaaggaaagg agggctgata gaaggagcca tttgatatca gtagataaag aatgccccat
    63001 gatggataag agagtctgac cagaaaagag ttttatacct gctgctctca tttccttaat
    63061 ccgagtaata atcaccagag caaagaaaga taagccaaat attgctaaac taattaaaat
    63121 aaggggattt agtaatattc gaaaagcaag aaaatagggc ggtatctttc ggtcagcact
    63181 tgctttataa cccaaatctc ctaatttatc ggcaagcttt tctttcgtca aggagcctga
    63241 caaaaggaga taactattta gcggatcact acgttcacga ctttcttggc tagcttcttg
    63301 gaattctttt ggtaaagttc cctgaccata agttgcataa gtaaagtgag tcgtcccatc
    63361 cttactcggc tctacaattc ttctagctat taaactctgt tctgagtttg caaaattctc
    63421 caattcctgt tcaaatacct cacgcgtcgg ttcctgagta tcttttttga cacgaagtaa
    63481 agaaacggaa tcatagcttg catataaata ttgtggcgca cgtaagacaa taatccaagc
    63541 aaggaagaag ctgagaaaaa aagttgataa taatatgaat agtttcttca tagtagactc
    63601 cttggtagac tccttgtaaa caaaattccc cctgtaattt cttacaaggg gaacgattta
    63661 aatcaatgaa cgattagtca taatcacagt aaaatgctac ttgttctccc catttagtcc
    63721 aaatccatgc ataggaggtt tttccagcag gagcttctcc tttatcagaa tgaccatccc
    63781 atctgctcac gatggatgaa taatgatatt ttttaccatg atagtaattt gaaaaagccc
    63841 aaccacctcc tgaaccttct ccatatgtcc atactcctcc atctggatat tgtacagcag
    63901 ttgatgcagc tcccaataat gtaaaacttg aaataagaac tagagcaagt aatctatgtt
    63961 ttttcgtttt cattttattt tttctttcaa aaaaagcaca ccttgagcaa caatgcaaca
    64021 aaataaaccc tcctctctct tttgttgaaa ccgctttctt atgtgataag aataacattt
    64081 ttattatttg ttgtcaagga aaaaatcgaa tttttagata ttttactata ttacctctat
    64141 gaataatatt atatagtagt tttatttcaa aataatatgc aaccagtact aagcaaatat
    64201 aaaatagatt ccattaaaga attttattca agtttttccc attcatatta tccaaacaaa
    64261 agagatggtg ataactcaaa aataaattgc aatcttgtaa aattcctagc aaaaaagaga
    64321 gccgaaactc tcttttttat cttcttttac tttttttgac tggcatgagt gtgatgtctc
    64381 taacactaaa gtaagctagg atcaacatgg ctattgctag gaatatttct gttggtaatt
    64441 gaaaaatttt cagaaaagat agaaccaata aaatcaagag tgccactaaa atacatacca
    64501 tagcgacgat attgacagtc cctttaatgc tttctggtgt cgcaaataca tagagtagga
    64561 gcagtaaaat tcctaggact aaatagacca tctttctctc tttctaactc ttattcagct
    64621 gattttttct tcttgttagc tttctcacgc tctgctttgt taaggatttg tttacgcaaa
    64681 cggatagact caggcgttac ttccatgtac tcatcgtcgt tcaagaactc aagagactct
    64741 tcaagggtca agatacgagg cgtcttgata acagctgttt ggtccttagt agctgaacga
    64801 acgttggtca tttgttttgc cttcgtgatg ttaactgtca agtcattttc acgagagttt
    64861 tcaccgatga tcattccttc ataaacctca gtacctgggt tgacaaagat cgtaccacgt
    64921 tcttcgatag acatgattga gtaagttgta gccttaccag catcgataga aacaagggca
    64981 ccacggtgac gtccaccaat ttcccctgga atcaatggca agtattggtc gaaggtatgg
    65041 ttcatgatac cgtaaccacg agtcattgac aagaactcag ttgagtatcc aatcaaacca
    65101 cgcgctggaa caaggaagac caaacgagtt tgaccattac cagttgaaat catatccaac
    65161 atttcacctt tacgttcaga aaggctttgg ataacagacc cttggtattc ttctggagtg
    65221 tcgatttgta cacgttcaaa tggttcacat ttaacaccgt cgatttcttt tacgataact
    65281 tctggacgag atacttgaag ttcatagccc tcacgacgca ttgtttcgat aaggattgac
    65341 aagtgcaatt ctccacgtcc tgaaacagtc catttatctg gtgaatcagt tgggtcaaca
    65401 cgaagggaaa cgtctgtttg caattctgcc tgcaagcgtt cttccacctt acgagaagtt
    65461 acccatttac cttctttacc agcaaatggt gagttgttga ccaagaaagt catttgaaga
    65521 gttggctcat cgatgtgtag gattggaaga gcttctactg catctgtcgg agtgatggtt
    65581 tcaccgacaa agatgtcttc catacctgaa acggcaatca agtcacccgc tttggcttct
    65641 tggatttcac gacgttccaa accaaagaaa ccgaagagtt ttgtaacacg gaagttttta
    65701 gttgtaccgt caagtttaga aagggtaact tggtccccaa ccttaactgt accacggaag
    65761 acacgaccga taccgatacg tccaacgaag tcattgtagt ccaaaagtga cacttggaac
    65821 tgcaaaggct catctgagtt atctactgga gctgggatat ggtcgataat cgtgtcaaag
    65881 attggtgcca tagtcgcttc ttggtcagct ggatcatctg acaatgaaga agttccgttg
    65941 atcgctgaag cataaaccac tgggaaatca agctggtcgt catctgcacc aagctcgatg
    66001 aaaagttcca agacttcatc cactacttct gctggacgag ctgatggctt atcgattttg
    66061 ttaacaacca cgattgggac aaggtcttgt tccaaggctt ttttcaatac gaaacgagtt
    66121 tgtggcatgg ttccttcata ggcatctacg accaagacaa caccgtcaac cattttcatg
    66181 atacgctcaa cttctccacc gaagtccgca tgtcctggtg tgtccataat gttgatacga
    66241 gttccgttgt aagcaacggc agtattttta gcaaggatgg taatcccacg ctctttttcg
    66301 atatcgtttg agtccatagc acgctctgcc aattcagtac gtgcatcaag cgtttctgat
    66361 tgtttcaata attcgtcaac cagggttgtt ttaccgtggt caacgtgggc gataatcgca
    66421 atgttacgga tatcttctct taattttgtc atgatttcct ctataatatt caaaatttat
    66481 tttctaactg aacgattata ccataatttc aaataaataa cataactcaa gcaagtgtaa
    66541 atgttttcac tccgcttttc ttttcacgtc aagccttttc aaagcaagcg acttatgata
    66601 agataggcac agtatgcgtt tagataattt attagctcaa gaaaaaatca gccgaaaggc
    66661 catgaaacaa gccttactca aaggggacat tctcgtcgat agttgcccag cccgatccct
    66721 agcccaaaat atcgatacag gactacaaga actccttttt caggatcgaa tcattcaagg
    66781 ctatgaacac acctatctta tgcttcataa acctgctggt gtcgttacag ccaacaaaga
    66841 caaggaactt ccgaccgtca tggacctgct tccatctgat atccagtctg acaagctcta
    66901 tgccgtcggc cgactggacc gagatacaac aggactcctt ctcttgaccg ataacggtcc
    66961 cttgggcttt cagctcctcc atccccaata tcatgtcgat aagacttatc aagttgaggt
    67021 taatggactt ctaacacctg accatatcca agcctttcaa aagggaattg tctttttaga
    67081 tggtactgtc tgtaaacccg caaaactaga gattctatct gcaagtccct ccctcagtca
    67141 agcctctatc accatttcag aaggaaaatt tcatcaaatc aagaaaatgt tcctctcggt
    67201 tggtgttaag gtaactagcc tcaagagaat ccaatttggg gacttcacat tgaacccaga
    67261 tttagcagaa ggtaactacc gccctttgaa ccaaaaagag ttacaaatca ttaaaaacta
    67321 tttagagatg agtcgataaa ataaagaaag ctttaaaact aaagcttttt tcttttattt
    67381 accgaaaaat taaggcgatt gctacaatcc agttaactac agaaatcaca attcctaaga
    67441 tattaagaat cttttctatt ttatagtcta attgtgactc tttttggtat gaaatagcca
    67501 agaccaatcc tatgataccc aaaatcaggc ctacaattgg aaataacaaa ccaagaataa
    67561 tcgacaagat acccacaaaa agtggatttt tcttcttttc tttcatgttc taagaactct
    67621 ttaaatttta tacaaattaa ttatactata aaacaatagc ttcatcctat cattcgacta
    67681 atttggaaat aaggttagct agtcttcact ttccctttcc aagaatccaa gccataagaa
    67741 aggatataaa tctcagaaaa accttgtttt ttcaagtaaa gagctgcatt tgtaactcgt
    67801 tgcgcacgtt ggttttcgta gagaaggaca ggtttatctt tacgaagggc tgcaagacta
    67861 gttttcaact gacttgaagg aatattgcgt gcaccaagga tatgttttct gtggaattct
    67921 gctgggtcgc gcaaatcaat caattgaccc gtacgaatca aggcttcaaa ctccttattg
    67981 tccacaattt tagccgcacg gcgaatacga agatagttaa agcccatcca cgccaacatt
    68041 gctagtataa gtgcccacaa aatccaagta accattagtt cttttctcca tttttctcaa
    68101 tataatccaa ttctaccttg tgctctctgc gaagaactgc ttctgcctct agatagtcta
    68161 atttatccat caaccctgca tcgtaaatcc gagatagttc caacttcatc agttcaatat
    68221 catataagcg ttttcccatg taaacaataa taccaaatcg tttgaggaat tgctgcacat
    68281 catagaatgt tttcataaga ctcattctag caaaattttg tgtttttttc aagaagagac
    68341 tcacacaatg ctccttattt tcctatcttc tttagcgatt ctaaggcaag tatggtacaa
    68401 taaaaacatg agaattcaac aattacatta tattatcaaa atcgtcgaaa ctggctccat
    68461 gaatgaggca gccaagcaac tctttatcac tcagccaagt ctctccaatg cagtgcgaga
    68521 tttggaaaat gaaatgggca ttgagatctt tatccgcaat cccaagggaa tcaccttgac
    68581 ccgtgatggg atggagtttc tctcctatgc ccgtcaggtt gtcgagcaga cccagcttct
    68641 ggaggaacgc tataaaaatc ctgtcgccca ccgcgaactc tttagcgttt cgtctcaaca
    68701 ctatgccttt gtggtcaatg cctttgtctc tttgctcaag aaaagcgata tggagaaata
    68761 cgaactcttc cttcgtgaaa ctcggacttg ggagattatt gacgacgtca agaatttccg
    68821 tagtgaggtc ggtgtcctat ttttgaacag ctacaaccgt gatgttttaa ccaagatgct
    68881 ggatgacaat cacctgctat cccaccatct cttcacagcg caaccgcata tctttgtcag
    68941 caagaccaac cctctggcaa agaaagacaa ggtgaaactg tctgatttgg agaatttccc
    69001 ttacctcagc tatgaccaag ggacgcacaa ctccttctac ttttcagaag agattctttc
    69061 tcaagaacac cacaagaaat ccattgtggt cagtgaccgt gccaccctct ttaatctctt
    69121 gattggtttg gatggttata ccattgcgac agggattttg aacagcaacc taaacggaga
    69181 caatatcgtt tctatcccac tggatattga tgacccgatt gagctggtct atatccagca
    69241 tgagaaaacc agcctatcta agatgggcga acgctttatc gactatctac tagaagaagt
    69301 tcagtttgat agttgagaaa tgataagaac caatatgtag gctagcaaca acctgcacat
    69361 tggttctttt tacttataat taaaagtttc ccctgccaac ttatcagcta gcttgggaaa
    69421 gagagtataa aacttatggg ctaggttcaa caaaatcggg agattgagtt ctcgtttatt
    69481 tttgcctata atcttgacaa tctttttagc cactgcatct gcctctaaga ggaagcggtc
    69541 aaccgattta agataagttc catctgggtc agcttggtca aaaaatcctg ttcggattgg
    69601 acctggattg actgttgtca catagactcc atagggcata agttcgagtc gcagagcatt
    69661 tgaaaaacca atagccgcaa acttggtcgc tgagtaaaga ctagacttgc cagtagctat
    69721 tagacctgcc atgctgacga tgttgatgat atgccctttg ctgctttcct tcatacgagc
    69781 cgcaaggtga cgagacagat tcatcagggc aaaggtattg acctcaaaca tctggtgaat
    69841 atctttatca gcaatctggt caaatccctc aaaaatcccg taaccagcgt tgttaatcaa
    69901 gacatcaatc ttgccatagc ggagataaag atcagttacc agagcttcta gggctgaatc
    69961 gtcggtaata tcaatttcaa tcaattctgc atgggaataa tttccgtaga gttgggctaa
    70021 tttttcctta tttctaccaa gcaagatgag ttggtcattg ggcaggagtt tgaccatttc
    70081 ttgagctaga ccaccgctag ctccggtaat gagaatagta ggcatactta tcctttctgt
    70141 gactgctaga tttccacttc ttccaagtct ttgaccacat ggacattttc aaaaattgtg
    70201 gcagcgtctt tcttgagttt gctaatatct tttgagagga aacgggcact gatatggttg
    70261 agtaggaggc gtttggcacc tgcttctacc gctacttgtg cagcttgcat attagttgag
    70321 tgaccatggt tacgagcgat tttttcatca cccttgccat aagtggactc atgaactagg
    70381 acatctgcat tgacagccag acgcacactg gcatccgttt ttcgagtatc tcctaaaata
    70441 gtgataatct tacctggacg tggcgctgag atatagtctg ctgccttgat ttcagttccg
    70501 tcttccaaaa caagatcctg gccgtttttg attttaccaa aaagcgggcc gaacggaaca
    70561 ccagcagcct tgagtttttc agcatccagc gtcccttcta gatccttttg catgacacga
    70621 tagccagcac agaaaatagt gtggtccagc tcctctgcat acacagtgaa tttatcggtt
    70681 tcaagaattt tacccagaga atcttggtca aactcatgga aatgaatgcg gtagggcaga
    70741 cgagaacctg acacacgaag gctggttaag acaaatgact tgattccttg aggtccgtag
    70801 atttccaaat ctgtctgctc ttcattggcc tgaaaggcac ggctagaaag gaaacctggc
    70861 aaaccaaaaa tgtggtctcc atgcagatgg gtaataaaga ttttgctgac cttacgtggt
    70921 cgaattgtgg tttccagaat gcgattttgc gtaccttctc cacagtcaaa gagccaaact
    70981 tcgttaatct cgtccaaaag tttcagggcg agacttgaaa cgttgcgggc tttagagggc
    71041 tgaccagccc ccgttcctaa aaattgaata tccattcgat actttctaat taatcaatat
    71101 ataacatggc tgtgcggttt tccgatcgga aatagcgttt gccagaaaaa gcagcagctt
    71161 cttgcaataa atcctcttgg ctgtagcctt tgagacgttt tcgaccatca gccaatcttt
    71221 ccaaatcagt caaagctgtg agactttcta ggctgacaac ttcctcgtcc tcgacaggct
    71281 tcatgtaaat cttaccagac tcttcaaaga ctaattgatg ggggaaaatt tgcgcaattt
    71341 caaagagcaa gtcatccgag attttctcct cattttcaga gaaaatccga ccaaagccgt
    71401 cactctcata acaaaaacca aaggatttac cagacagatt aagccgaata aaagacttat
    71461 tttctagggt gaaacttggc tcagtattgt aaagattcag ttcctgactg agttctgcaa
    71521 aataatccgt cgcagcctga ggactttttt tctgatagag ttctgcaaag taggcattaa
    71581 caacacttgg cggaggtgta ataagtgtta actgctcctg ctctgtctta ccagctagaa
    71641 gctgatccag atagaccttg tccagacttg tataacctcc atactttaga gccaaagttt
    71701 taatatcagt cataaaattc ttctaacctc catttatttt tctcggaaat gtagcctgta
    71761 atcacttcgc cgtcttcctg ataatcacgt tcttccagaa ttgcaacact ctctaaatca
    71821 tgaatcttgt aggactttga aaaaggcact cgcagggtaa atgcttcaaa aatttcctta
    71881 atcttatcta gcaataatgc ttgcaagttt tcacgactgt cctcagactt ggcagaaatg
    71941 agggtatatg gcgtttgggt aggcgtgaaa tcctccacca aatccgcttt attataaagc
    72001 gtcaagtgag gaatatcttc catgtccagg tctttcatga tggagagaac cgttttttca
    72061 tgttcctcgt ggtaaggatt gctagcatcg ataacatgaa ccagaaggtc cacatgcttg
    72121 ctttcttcca aggttgactt gaaactggac accaactctg tcggcaaatc ttggataaag
    72181 ccaacggtat ctgtcaaagt tacttggagg ttgcctccca gatgaatact cttggttgtc
    72241 gcatccagag tcgcaaagag ctcatctgct tcatactggg tcttactggt caagatgttc
    72301 atgatagttg atttcccagc attggtataa ccaatcaaac caatcttaaa agtgctagac
    72361 tccaaacgtt tttctctgac agtcgcacga tttttctcaa ccaccttgag ctggcgctcg
    72421 atatccgtga tttgattgcg aacgctacga cggttcagct ccagttggct ttcaccagga
    72481 ccacgggaac caattccccc tgcctgacgg ctgagcataa tcccctgacc aaccaagcga
    72541 ggcaagaggt atttgagttg ggctaggtgg acttggagct tcccttcatg gcttcgagcc
    72601 cgcatggcaa agatatccaa aatcaactgc atacggtcaa tgaccttaac accgagaact
    72661 tcctctagat tgacattctg ccttggggtc agacggttgt tgacgatgac agtagtgatt
    72721 tcttctgcat ccaccataag cgcaatctct tccaacttac cagagccgac gaaggtcttg
    72781 gaatcatatt tttcacgttt ttgtctgtag ctatctacaa cgactgcccc tgccgttttc
    72841 gctaaactag ccaattcttc catggagagg tcaaaactgt ccataccctg caattccaca
    72901 ccaatcagca ggactcgctc ctcttttttc tccgtttcaa tcatctaaaa actcctctat
    72961 ctggcttaaa atgcggtctt gtacaccaga ttctccaatc tgataaaagg tgacctgcat
    73021 gcgattacgg aaccaggtca gctgacgctt ggcaaaacga cgggtcgcct gtttgagact
    73081 ctcactagct tcctccaagg tctgctctcc acggaaataa ggaaagagtt ccttatagcc
    73141 aattccttta gcagcctgta cattagggga atggtcaaac agccacttgg cttcatccaa
    73201 aagcccagcc tcaaacatca aatccactcg gtggttgata cgctcataaa gttgactacg
    73261 ttcatcatcc aagcagataa tcagcggttc atacaaggtc tcttgatttt ccaaatcctg
    73321 accaaaatgg gcaatttcta aggcacgcat agcacgacga cgattaaact ggggaatctc
    73381 aaggcctgct tgatccacca aatgggctaa ttcctcatct gaatatggct ccaaactagc
    73441 tcgataagct aaaatctcct catgaggagt ctctccacct aggtggtaac cttctagcaa
    73501 gctctggata taaagtccag tcccaccggc gataatggct agcttgccac ggttgtgaat
    73561 accctcaata gtcatcttag tttctgaaac aaaatcaaaa gccgagtaag actcggttat
    73621 ctctctaaca tcgattaaat gatgaggaac agctgcctgc tcttctggac tagccttggc
    73681 cgtcccaata tcaagtcctc gatagacttg ctggctatct ccactaacca cttcgccatt
    73741 aaaacgcttt gcaacttcaa tagctagagc cgtctttcca acagcagtcg gtccaacaat
    73801 cacaattatt tttgttttca tcttttttcc ttgaaaaatt cccatttttt cgttactatt
    73861 attataacac aaaaaggtca gtcagaaaaa tgtgacctct tgaggaggct ggctgattga
    73921 gaatataaag gaggaagact catggctaaa ggattcgcta aaggtcttgt aacaggtgtc
    73981 gcaggaactg tcgctgccgt tgcaggtgca gtatacgcat ttaaaaagaa agtaatcgaa
    74041 ccagaagagc aaaaagcagc tttcatcgaa gaaaaccgta aaaaagcagc tcgtcgccgc
    74101 gtatcacgtt aagaaacaaa agaagttggg attattctca acttcttttt tctattcttt
    74161 taaatagcta ggtcaaactt caactgtggc ttaacagggt cataatccac caactcaaaa
    74221 tcttctgctt tgatatcaaa gaaattagtc ccatcaggaa catttaaaac caagcgtggt
    74281 tggcagtttg acggctcccg acggagcaat tcctgagctt gttcaaattg attatcatag
    74341 atatggaggt tgttgatgaa gtagaagaac ttcccaacct tccagccaaa atgtttggca
    74401 atcatcatct gcaaagccac atactgcata gcgttgatgt ggtgggctac tagcatgtca
    74461 ttggagcgct ggatcaaggt cgcatccaga tagatttccc catcaacacg ccggacatca
    74521 aacatggtct gaaaggcgca cgggagcagc ccatctgttt cttcgaaagc ttggtaatcc
    74581 cagagcgaaa taatattgcg gcggttccaa ggattggttt ccaactgttt gagaagctta
    74641 ttgataatgt cgtgtttctt aacaacggca ccatagcgct caccaatggt tcccgtgtct
    74701 ccaacttccc agtcattcca gtagtgaaca ttgtacttgt cattaagcac ttctaagcta
    74761 tttgactggt cttggtaaat ccagagaact tctttgatgg cggatttgat tgcaatggga
    74821 cgcaaggttg tgataggaaa ttctccttta gataagtcgt actcggaaaa ggcaccagtt
    74881 acatacttgg aattagcaac agtcccatcc ttgtacttag gacgagcctg ctctgagaaa
    74941 acaccttcct ttagaatgcg ttcaatattc tctttaaaaa tcgtatctgc ttttgtcatt
    75001 tcgtttcacc tcattcattg tcctaactag tatagcataa aaaataaaag aggaacatta
    75061 ctaactctag gttagcattt tcctctctca ttatcttatt gcaatacaag tgatgctgct
    75121 ccgataactc cagcgtcatt tcctagagtt gcaagagcta atttagtaga tgtgcgtact
    75181 tgtgggaaac tattttcatc gtaaactttt tgaacacctt gtagaaggaa ttctcccgca
    75241 gctgacacac caccaccgat gacgattgtt gatgggttta ggattgaacc aatgttagca
    75301 caagcgattc ccaagtaacg tgagaagtta cggtaaacaa tcaaagcaag gtcgtctcct
    75361 tcttttgcga gatcaaagac agtcttagca gttacttctt ctccgttatc aatcaagcgt
    75421 ttcaaggctg catcgccttc gtattcatcg gcatagcgac gagtcaagtt gacaatccct
    75481 gttgctgaag caactgtctc aaggcagcct ttcttaccgc aagtacatgc gattggctgg
    75541 tcaaagtcaa cagtgatgtg accaagctca cctgctgcac cagcaacacc gtgaagcaat
    75601 ttgccttctg cgacgatacc gccaccaaca ccagtaccga gtgtcataaa gacaacgtct
    75661 ggttggttat ctccagcacc catccagcgc tcaccaagag ctgctacgtt ggcatcatta
    75721 tcgatgaaaa atggaatgcc caaagctttt tcaatctttt gtttgattgg ttgaagggtt
    75781 ttccagttca agttgtaggc accgataaca gtcccttttt cacggtcaac cacacctggt
    75841 gatcccattc caatgccttg gaagtccgct gctgccaatc caagcaagtc caaacgatgt
    75901 tgaatagact caatcatatc atcaacgata tgacttccct catccaaaat gtttgtcttg
    75961 attgaccatt ttccttggat ttctcctgct gttgttaaga ttgcaaattt gatagaagtt
    76021 ccaccaaggt caatcccaat aatcttttga ctcatcatat tctccttttt cattgtgtag
    76081 taattgaaaa tgcttacagt actagtatat caaaatccat tcacttatgc aaaggtttgc
    76141 gtaaatgaat tataaggaat tttttcgcct accagtatct gttaatcatc taaatgatca
    76201 atggcatatt gagctgcatc atttgaaaat ttatcaaaat cagaagttaa ttgtctatac
    76261 atacgttttt ttgacatgtg gaataacgaa ttataacttt ttgcctttcc taaagcagca
    76321 gaatattcac tattgctatc attactagaa gaagctgtac ttgcttgacc ttccttccaa
    76381 actccgtcat cgccaacata ataacgtcca ccatcaaccc attcattgac agccatttta
    76441 ccatccgatt ttagatagta atttccttgc catgtactgt aagcataaga accatctgat
    76501 gtcaaataat accaagcttg ataagaagag tcataaatcc attcaccttt agccatttta
    76561 ccatctgatt tcaaatagta attgccttgc catgtactat aagcatacga tccatctgat
    76621 ttcaagtaat accaagcctg ataagaagag tcataagccc attcgctctg ggccatttta
    76681 ccatctgatt tcaaatagta attgccttgc catgtactgt aagcatacga tccatctgat
    76741 ttcaagtaat accaggcttg ataagaagaa tcataaaccc attcgctctg ggccattttt
    76801 ccgtctgctt tcaggtaata gcttccctgc caagcatttt tcactggatt tccatttcca
    76861 tcaaagtagt accaagcgcc gtcctgctta acccaaccac ttgttgttgc tgaacttgtg
    76921 ttgatttgag tagccgttga ctgttttgct ttaaaagcac ccttaggagc atttttcaat
    76981 tcgcaagcca caccatcatg atcacggtct aacttggcag aataaccagg ttctccctcg
    77041 tgaatatccg aatagccatt cccccaagct tccttacagc tcgaaaaatg gatgttttct
    77101 tccgccaaaa ctggttgtga aaacaaggct aaaactggta atgtagccag actcattttt
    77161 aaaaatagac gtttgttcat ttgtttctcc tataacgata atatcgattt tagtattatt
    77221 ttacaaaact tatttcagca attcaaggaa acttctgatc ttttctacaa actcctttgg
    77281 ttttgcctta ttcaagacat gagggccatc aggaatgatc tgaaactgcg aatctgtcaa
    77341 cagtctatgg agagttttca tagaactaag attcggtcta tctttgctgc cacaaattag
    77401 taaggttgga taggggcaaa tccctgctat atccgttaaa tcaagtgtct tcaattcctc
    77461 agaaactccg atcataagag tcttatctgc tccctgtttt tcaaataccc ttttgggaag
    77521 tagtttaaaa atcagcaact gaagataaaa tagaatattc cctgctaatt taagcgggca
    77581 tcctgataga accaaagctc gaagatttgg taaatcgtaa ctggaaagtt ctagtgccag
    77641 ggcagcacct aaggacaatc caatcaaaac aaaaggttct gtctcttgag ctaggtgttg
    77701 ataaactcgc tccttggctt tttgatagct gctaactcca gaaggaaata actcaatagc
    77761 ctcagaagga taatctgtca gtagatttcg aacttctttc caagactctg ctgactgccc
    77821 taacccatgt aaaaatatca gtttcatcta gttctcctgt aagattaact catacaagcc
    77881 tctcactgca ttacagccgt aaatagcttc tgcttgggct aaatctgcca aggtcaagac
    77941 tttctcttct acctgtcctc tttccagcaa atgctgacgg taaattcctg gcaagattcc
    78001 aagttcgata ggcggtgtgt agagtctccc agaaattttc agaaccaaat ttccgattga
    78061 ggtttccaat agctctccag ctgcattatg gtaaataatt tcctgcttcc ttaggcccaa
    78121 gtgaggtcgg tggcttgttt tgaagtaggt aaatgcttgt tgcaaattgg cttcctgaag
    78181 acagagttgg gcatagcaga aggttcgact gagaggtgtt aatacttgac gattgacttc
    78241 tatctctcca gacttgctaa ggctaattcg caagcggtaa tcttgattaa catcacaatc
    78301 ctgacactct tcctttatct tttgtttcaa gtcttctgca tcaaaaggag aagcaaaata
    78361 gcgactagct tttctcagcc tttccagatg ttgtgcttca aacagcaggt tcttctggct
    78421 gattttccca gtagtaatta gctgaaaacg agcttgttta cgatagagaa cagctgcctt
    78481 ttgatgaacc tcttggtatt cagattccca agtgctatcc catgtaatgc ctccgccaac
    78541 tccatagatt gcttgacctt tgtgaagttg aatggtacga atggccacat taaaaatccg
    78601 tcgtccattt ggaagcaaga gaccaatcgt tccacagtag actccgcgtg gttgaggctc
    78661 taaatttttg ataatctcca tagtcgcaat tttcggagct cctgtgatgg atccacaagg
    78721 aaagagagag cgaaaaatgg taatcaagtc aacatctgct cgcaaccgac tcttgatggt
    78781 cgaggtcatc tgccaaacag tagaatactg ctctacctga cacagatgct ccacgtgctc
    78841 actgcccact tcagaaatac ggttcatatc attgcgcaag agatccacaa tcatcatgtt
    78901 ttcagagcga tttttggggt cctgttctaa ccaactggcc tgttcaagat cttcttggtc
    78961 agttacccca cgctgggtcg ttcccttcat tggtctcgta gccaattcac ggccattttg
    79021 ctcaaaaaag agctctggac tcatggaaat cactgccatc tcgtcatgtt ccacataggc
    79081 attgtagccc gcctcctgct ctatcaccat acgattgtag atggcaaaag gattggcatt
    79141 taacttttgc ttaagttgga cggtgtagtt gacctgatag gtatctccct gccgtaaatg
    79201 atgatgaatt tgggcaatcg ccttctcata gtctgctgca gacgtcactt cctgccaatc
    79261 agaaggcaaa tcaacctcat cataagtcag aggaataggg gatgtttcta cactatcatg
    79321 aactgtaaaa tatagcaggt actctcccag tagaggagcc ttatgaactg caaacttctc
    79381 ctcaaaagca ggagcagcct cgtagctgac atagcccacc acataatagc cttgcttttg
    79441 gtagctttcc acttgtgcca gcaagtctgc cacttctgct acatttctcg tttttatctc
    79501 tttgataggc tgggtaaagg tgtatctctc ccccaaagcc ctaaaatcaa tcactgtttt
    79561 tctatgcata ccttaagtat agcataaaaa ggcagatcaa gaaaaactta atctaccttt
    79621 ttatgatttt atggctctat aatatttgta gtgggtaacc cccctatgga tattacggag
    79681 cctattttgt gtagaaaaaa aatcccataa gatctataat gaaaagcgac aaaacaactc
    79741 attagaaaga atcatatgga acaattacat tttatcacaa aactccttga cattaaagac
    79801 cctaatatcc aatttatgga tatcatcaat atggatacac acaaggaaat catcgctaaa
    79861 ctggattatg atgccccatc ttgtcctaat tgcggaagcc aaatgaagaa atatgacttt
    79921 caaaaaccat ctaaaatccc ttaccttgaa acgactggga tgcctactag aattctcctt
    79981 agaaaacgcc gattcaagtg ctatcagtgc tcgaaaatga tggtggctga gacttctatc
    80041 gtcaagaaga atcaccaaat ccctcgtatc atcaaccaaa agatcgctca aaagttgatt
    80101 gaaaaggctt ctatgaccga tattgctcat cagctgtcta tttcaacttc aactgttatt
    80161 cgcaagctca atgacttccg gtttaagcat gatttttctt acctccctga gattatgtcc
    80221 tgggacgagt actcctttac caagggaaag atgagcttta ttgcgcaaga ttttaaaaaa
    80281 ctcaacatca tcgctgttct tgagggcaga acacaagcca tcattcgaaa tcactttctg
    80341 cgctacgata gagctattcg ttgtcaggta aaaatcatta ctatggatat gtttagccct
    80401 tattatgcct tggctaaaca gatttttccg tgtgctaaaa tcgttctgga tcgctttcac
    80461 attgttcaac acttaagtcg tgctatgagt cgtgtacgtg ttcaaatcat gaagcagttt
    80521 gagcgaaaat cccatgaata caaggctatc aagcgctact ggaaactcat tcaacaggat
    80581 agccgtaaac tcagtgataa gcgattttat cgccctactt ttcgtatgca cttaaccaat
    80641 aaagagattc ttgataagct tttgacctat tcagaagact tgaaacatca ctatcagctc
    80701 tatcaactct tgctgtttca ctttcagaat aaggaaccgg agaaattttt cggactcatt
    80761 gaggacaatc taaagcaggt tcatcctctt tttcagactg tctttaaaac ctttctaaag
    80821 gacaaagaga aaatcgtcaa cgcccttcaa ctaccctatt caaacgccaa attggaagcg
    80881 accaataatc tcatcaaact tatcaagcgc aatgcctttg gttttcggaa ctttgaaaac
    80941 ttcaaaaaac ggatttttat cgccctgaat atcaaaaaag aaaggacgaa atttgtcctt
    81001 tctcgagctt agcttttctt caacccacta cagttgacaa agagccgatt ttattcatct
    81061 tatgcttgtg atgtattaaa tagatcacca gagaaaccgt ctgattcttt tagtaattgt
    81121 ttaaagactt tttcttttaa tgcaacagta tgtctatatt tatttttaat tgtttgatta
    81181 gacaattcat ttaaatcttt ttgtactgct tcattaaata attcttttaa tctagcataa
    81241 gttgaaattt gttcattatc aacagatata ggaacaaatc ctttagttgt agctttatta
    81301 tatatttctt cgtaccaaga atttttccat tcttcaagag tgttgaatct accttctgaa
    81361 actttttgga tgattaactt atcacttagt aagccgttgt tttctttatt agcaatatct
    81421 ttgtatttat ttgaagcata tccaacaaaa cctttttcat atccaaaata tccccacatt
    81481 ctaaatgtgt tgtgtttaaa cgacaatgca ccaacagcac cttcacttgt gtttcctccg
    81541 taaatacctg ccatcatatt tactgttaca taagcagagt ttggagtgaa gtcctctggt
    81601 ttaaacacac cgtttccaac accatgtcta gtagcaaagt tattatctac taaatctttt
    81661 atagtattta atttaattac tttctcgtcc tcattaaggt cgcgaactaa atcccattgg
    81721 tttggagcaa ctaaattatt gttataactt cctttttcac gcatttttct gtcaactttc
    81781 ttaaaccatt gactgttatc agataagttt ttacttaaaa cagattcagc ttcaacatag
    81841 tctagtaaca tcattgcttc attatatcgt ttcatataat catcaatttc ttgtctattt
    81901 tttaatttat ttggattgta attataccat tggttcccat cattatttct ttcataagcc
    81961 atgttgatac caagggctcc atattcacca ttaggattag aaacagatgg agattgcaac
    82021 atcccttgag caaaagcttc cacaaaagtt ccctctctgt gtcgccatcc tccaagataa
    82081 gctaatctat cattaatatg agttgtttcg tgtgtgaaag cagagatacc aaaatcacta
    82141 atcatatctg taaccatata gtaaacagat tcttctttgt atggattatc ccagatttta
    82201 gccattgctc ccatattcca gtttggtggg aaatatcttc cagtaggacc aaataattct
    82261 cttgaaggag cataatcaga agaaccatct ttatatccat atttatctag ccaaccataa
    82321 ccaggtgcgt tcatattatc ccagacaggt gaaggaacta cattttgact ttttagtaat
    82381 ttatttctta ctttgtcgga agctagtcta ccccagaaat ctaagtaatc ttgttgtgct
    82441 ttagcaactt tatcaatttc ttttttgaat tcatttctag cttcttctgt gtttttacca
    82501 tatttttcaa aagcactata tgccattgta ttatatgttg aaattaagaa tatatgtgct
    82561 tttttaagat ttaataaagg taaaatcatt ctgctatgaa catcattgtt tagaccatca
    82621 tatgctctat gttttttatt cttgaaatct tcaattgaag tttctggttc aacaatataa
    82681 acatttttct tagttgcgtc tttaaaccaa tcgtttatat ttgtatattc agttaataaa
    82741 ttcatattat aatgtaaaaa tccatttaat tcatttattc caattattcc acctatagtt
    82801 tcacgataag cttctaaagt tctatctcct ttaacatttt tttcacttga acctatttta
    82861 attaagaaat ctaagaagtt aacatttttt ccgtaaaagt caggtttaaa caacataatt
    82921 tctttaatat tcatattatc aaaattaatt ccataatagc gatttaaata agctaatcct
    82981 agcattattt tttctttatt ggcttctatt ttttgaagta aaacatcttc tgaagcttta
    83041 ctttcattta attgaaaatc ataatttaat aacaatttgt ttactaagtt atctaaatta
    83101 tttttcactt cttcaaaact ttcttctaag aataaatctc ttacatatct ttttcgtctt
    83161 tctgttgtat tttcttgagg attattacgt ttatccatta aattatacat tccatcagat
    83221 tgtaattcaa cagaatttaa tttttcttta attttacttg ctatagaatc tctatctttt
    83281 gctatcatgt taggtgtata aacaatgtct ttcaattcgt taatactata ttccttaatt
    83341 tggctaacat ttgaatcttt ttgtacaact gtaaaaatat cttttgtttt gtctgaataa
    83401 tgtactaata ttttgtttac ttcggataaa tctgtaacaa agtcattatc tttcattcca
    83461 ataacagata taactttttt atttaataag ttctcattag ttaatttatt tccttgatta
    83521 actatccatt ctttattata aaaaggttgt aatttagcaa tatttctata tgcttgttct
    83581 tttgttttgt cataatcttg tgttgtttta tattcatcat cttttgatat gttattattc
    83641 aacttatcta ctaataatgt tggagcctca aaatctttgg cagtaatacc aaaatcttct
    83701 aattttttat cagcttcttc tttagaaatc tctttaagtc tattcgcatt ttttcttgtt
    83761 acattaccag ttgcttctcc agctacgcta acaactctac ttaaataagg gaatccaaag
    83821 tcatcatctc caatgtctcc tgaaccatac agtttttcag cattagttac tttcacataa
    83881 ctaattacat cttccataaa tccataaggc cagtttttag aaataactcc acctgtttcc
    83941 acattgtttt ttaagtttat tgatcctttt gctacagctt ttttaatatg tccattagct
    84001 cgcacatccc ttggatccgt acctctgtct aatgttgaaa ctaaagctga acctctggct
    84061 ctttctcctg taatctctac atctgtataa actctttcaa tgtttgcttt tctctggtta
    84121 ttaactaaac cagatatact ccaacctttt ttcccttctg tgtgtaattt tcctataaca
    84181 gcaacatttt tcatcttgct accgttattt aaattattaa caacaccagc tacatcatta
    84241 ctacctacaa tacttccagt aattttaatg ttttcaatta ttgtatttgt tgcatccttt
    84301 cctaatgttg ctatttgttc tgtgtttggt ttgtttatgt ttacattaga aaaaatcaaa
    84361 tcttttattg tagcattttc tatttcatta aataatggat tagctaagtt atgtatagca
    84421 aacttattcc catcagtact tgttaaactt cctttgaatt tctttgtaat ataagatttt
    84481 ccatttggtt taatattagt agcgttcaaa ctttctccga ttttataatc tccttctgga
    84541 ttgttttgaa tagcttcaac taattctcca aaatcatagt aaacattgtt ttctttttgt
    84601 tttggttttg ctatataata agtatattca tttttgattt gttcttcttt agtatgttga
    84661 attaaatcag ttgcttctga agtaatctta taaaagtttt ctccatctac tgtttcttct
    84721 gtaatagatt ttactgctaa tctatttgtc ttattatcat ttgttgtgat ttttaaataa
    84781 taattatttt tatctgtagg aattgttgtg aaattagtat catctatttc ttctttattt
    84841 tcactaactt ttattagttt cgtagactta atatctttaa tctcaatttt cttaaggtca
    84901 attcttaaag attcttcatt cagaacttct tcctcatcac cctcaccacg gtcataaacc
    84961 atctttgttt caagtttata atccttgtag tattgcaaat ctgtcaggct ggctgtcaag
    85021 ttgtcaggtg aaacaatcaa tgttttcaca atctcatcac cttttttcag agttaaggtg
    85081 atggatttaa tggtcgcctt gcttggattt tctagactgt atttaacatc tgaagtacgc
    85141 ttcaaatcct tagactcaac cgccgttata gtcaatactg gtttttcaaa aattttggta
    85201 ccacgtttca aaattttgtc ttgagggacc tcaatgactt cctctataac ttttggagcg
    85261 tcttctgttt taactccttt gatggtatta aaggtcttag taattttttt ctgaccttct
    85321 ttgccttctt gagctacgac ttctgaacct tttttcagtt gatcatcttc ttcaatcttt
    85381 tctttaaatg gaatcttttc aagactttct tctacaagag tcccttcaat tggttttgta
    85441 ctacggctta cctgttgatt tacatgctcc ttggtcactt ccgtactggt tgaaagaact
    85501 tggtcagttt taacaccttc tactgtttta tagattgttt ttgtaacttg acttcctttt
    85561 tcaccagttc gtaggacagt ttcttcatct gtatacttag ttggatcatc agtcgtttca
    85621 gttttatagt taagttctgt agttgtttct tcaacaagtg ttccttcagt cactttatac
    85681 tcaggtaatt gttcttgagc aagagcctca tccacgtgac cttcttcttg cgtatcttta
    85741 gctgttttgg tctcctcttt tggttctaca gtttcttcaa ccttggcatc tggagttgat
    85801 tcttcttgtt ttggggcttt ttctacagcc ttctcttctt caggagcttc tggttgcttt
    85861 tctggctcga ctggtgcctt ttcgtcttcc cttggcgcga ctggttcacc tgcttgttca
    85921 acttttggtt cctcagctgg tcccgtttgt ttttctatag caggcgtttc aacttttggt
    85981 tcttcgacaa gttgattagc agcctcatct tttgtttcta ttactgctgg ctgttcatct
    86041 tcttgtttcg gtgtctcttc cgctccccta ttttctgtag gattttcttc ttgtgatgat
    86101 tcttttggtg tccttggttg aacgggttgt tctggaattt ttggttgttc tactggagtt
    86161 gcaacttttg attcctcagc tggtttgtct gatggttgac tttccgattt gactggtgct
    86221 tgttcatctg tttttgactc aactactcca cttacttctt caactggagc tggttctgct
    86281 gaaacttctt tttcctcttc tactttagga agggtttcgt cagtaggatt tacctccgat
    86341 tttggttctt cttttggact ttcttctgtt ctaggtgctt gttcttttgg agcttcctct
    86401 gtctctactg cttggttttc tggcctcact tgctcctgat ttgttgttga ttgaggagtc
    86461 tcaacttcga ctacagtcac ctctccagat ttaactgaag cttcttctaa aacagtgtcc
    86521 aaaccaagcc ttttgaggat ttcacctgat agataaccca catagcgata gccctccatt
    86581 tcaacaacat cctctcgact agccggtgct agggtcgcaa ctgggtctac agcccctgca
    86641 ttaggaagga ctaccaatcc catagctcca actagaaagg cgctagcaat tttctttctc
    86701 ttgtagatta aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa aacagatgct
    86761 tctgtgcctg tttgaggcaa ctgagctttt tgatacacca aaccatagac aacttcatct
    86821 ccatcaggat ttcctgtctg gattaaatct ttagcttctt gtgaaataac ctctttatct
    86881 acatagtgat aggtggctgc gtccactaca gaaggagcca ttaaaaggct tccaagaaat
    86941 acagaaccta caactccctt aatcttacga attgaaaaac gatctttttt aaacactttc
    87001 atctccttta ttcattctta cgactttcta atagaatctt gcggatagtg cgcacgcgca
    87061 cctccaatta attttggacg actagccagt gccgttacgt gggcatgacc aatctctctc
    87121 aaaagagggc gaatcggaac ctgaacatgc ttgacatgca tgccaattgc agtgtctccg
    87181 atatccaatc cagcatgagc cttgataaat tcaacctcaa ctggatcctg catgaacttg
    87241 aaggctgcta actgccccga acctcctgca tgaagtgtag gaaggacact gacaatttcc
    87301 agaccaaact gctctgccac ctgacgttca acaacgaggg cccgattgac atgttcacaa
    87361 ccttgaacag ctaaatggat acctctagta cctagaatac ccaagatagt ctccactatc
    87421 agctcgccaa tctcttgact ggattctttc ccaatctgac cacctatcac ctcactagaa
    87481 gaaaggccta aaacaaagat ggagccttgt ttcaaattgg ccttctctaa aacatcttct
    87541 aatatctgac gtgtttctct ttgaatctgt gtctcattca tctctgccac ctcttttatc
    87601 actcttctat cataccgttt tttcttgttt ttagcaagat agacaacctg gaaagcttgc
    87661 ccaattacgc ataaaactcc cagaattgac tgggagttag ctagtttcta ttctatttat
    87721 gtatatttcc actttcgtcc ctttttgggg gctagaatca atcttcatct ggtaattggc
    87781 tccaaaatga agtttgagcc gttggtcgac attttgaaga ccaactcccc cacgtttgag
    87841 ttgactttga ctactatcgc cagcagcttg gaagccaacg ccatcatcct caatacggat
    87901 gaccaagcct gtatcctctt tctggacaga gaccctaata tgtccctgac cttccttttc
    87961 cttgatgcca tggtaaagag cattctctac aaggggttgc aacaccagct taggcaaaac
    88021 tagatgatca aaggcaggat tttcagcaat ttcatagtct aacttatctc catagcgttg
    88081 tttctggata aagagatact ggcggacatg attgatttcg tcagacaggg aaatcaagtc
    88141 cttgccttga ttgagcgcca agcggaaata ggttgccaag gacttggtca cctgaaccac
    88201 tcgctgactg tcctgaaatt cagccatcca gatgatggta tccaaggtgt tatagaggaa
    88261 atgggggtta atctggcttg atagggcttg aagttggtac tgacgggtcg tttcttcctg
    88321 gctacgaata tctgccatca gttgatcaat ctgatccagc atggcattga actgacgagt
    88381 cacttctctc agttcatagg caccagtttc ttcggcgcga agattttgag caccagaggc
    88441 aatttccagc atggtttctc tcagatcctt caaaggagca atccagcgtt tgagactgaa
    88501 ccacaccaag cagagaaagg caaaaagaga tgtgacacta gcccaaagca aggtccacat
    88561 gagttgactc cgaacctgat ctaacttttc caatgatgac acgccaagca ccgtccaatc
    88621 agttcctgca atcttttcct gactgacgta ggattggtgg tctagtgtat agccctgacc
    88681 tgtctcgatg tagggtttca tagcctccat tttgctagac gaactataaa ctgtgtgttg
    88741 aggatggtag acaaattcat ggttttcatt gataatgaag gcaaagccct gctgccccaa
    88801 ctggagttga ttgagatagg cttccagagt ttcataagaa atatccaaac gaagcacacc
    88861 cagattggct cccttcgcat caacaagttc ttgagtaaca gaaatgaccc attggctgtc
    88921 tgacttacgc gctggggtca aaacgggcat ggctccctga tgaatagcct tttggtacca
    88981 atcctcagtc atcatatctg aggatgtttt catctgcaca gtgtcatctg tagaaatgac
    89041 ctgacctgac ttggttacca gtaccaccgt tttcaagtcc tgatccgcct tcaagatggt
    89101 caaaaacaga ttttggattc cctttactct gtcttggcta ggattctcag cataggctag
    89161 gacatccgtc tgctgggtca aactggtcga ggtcgtttct aattttttga tataagactg
    89221 gataaagtgg ctagtctgac tgatagtcgt ttggctatcg ccttcaatgg tagcctcaat
    89281 ggctgatgaa ctagatcgat agtagaaagt cccaaccaca gctaggagaa tgagaaagac
    89341 cagaaagatg gaaataacca ttctaactaa aagagaagaa cgcttcatcg gccttctccc
    89401 ttcttaaact gacgaggtgt cacacctgca atctgcttaa aacgttgggt aaaatagttc
    89461 atatcttcaa aaccaacctt ctctgcaatc tcataaatct tcagatctgt agttaaaagc
    89521 aagagcttag cttgtttaac acgttctctc accagataat cctgaaaagg caagcccaac
    89581 tctttcttaa tcaaggaact cagataggtc ggactaaaac ctaagtcact ggctaaagac
    89641 tttaaactaa attggctatc agccagatga gactggattt tctgggccat gtttccttca
    89701 aacctattag tcaataaatc ttgtaactgc tcttctttct cttccttgtc tagtttttgt
    89761 ttgattttcc ccaacatttc ctcaatatca tgacgagaaa agggtttgag caggtagtcg
    89821 tccacaccta gtttgacagc agacaaggca taatcaaaat catcgtaacc tgttaaaaag
    89881 accaaatgaa cctgaggata ggtttctcgt accagactgg ccaactggat gccatttaga
    89941 tgaggcatgt tgatatcggt taaaatgata tctggcacct gcttttggat caattcccaa
    90001 gcctgccttc cattttcagc ctgaccgatg atttccatat cgtaggctgc tacattgacc
    90061 agtttagtca aaccttgtct taccagatat tcatcttcta cgattaagat tgtgtaggtc
    90121 atgcttctct ccttatgtca cttactagta tcagtatagc aaaattctcc tctaactgct
    90181 taggaaatac ctcttatact caatgaaaat caaaaagtaa actaggaaga tagccacagg
    90241 tttctcaaaa taccgctttg aggttgta
//
LOCUS       DAVFJR010000004        85361 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVFJR010000004 DAVFJR010000000
VERSION     DAVFJR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 85361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.004"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(538..4104)
                     /locus_tag="VU722_000371"
     CDS             complement(538..4104)
                     /locus_tag="VU722_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU1771419.1"
                     /translation="MFLYLKGLGKYRKSKAYGLVGCLALVSMIGLAAPDLPVIGGGVV
                     AADVIQGGNDIKDVNVHSKSAEGVAMTYTTYDSGTSGKQTASGSGVFVAPNVMVTVAH
                     NYYDKNQEDKSAVLRGGASARSYVVMNSETEKHNKVPTSGVSETLEKDSIHLYDEKNF
                     GKDYSNDLAVVVTKKTVEAMTGGEDSPRELSHKEVSTGDKISMVGYPNDFSTPNLSAE
                     NKARLKDGKAYSVTTTVSSVNKESGTVTYHSSALGGFSGAPLFNDKGEVVGIHQHGTN
                     TPNAQESERIGGGTLFTEKHRAWIRSMIDKYGIKGWYIDGANRYYYDENHRALKDVES
                     EIDGALYRFDEKGRATLLEGEEKGRVLLRVEDTKGTPLISDKVVQEGSVGSGLNFHLR
                     QNPNFKQLIATSPTAKVVSYNGVPINKLASDTSWSDEYVSKLALGDTIIRAVVDSVTP
                     PSTSSSDFARTEVGKVDLSGKSNLPVPSKEVLQAPNGSENFYATTHIQTPDGSGSGTL
                     IAPNLVLTVAHNFLTVKGSEVVTKSGRTNTVYKATLPSGQPVNFSDDDIVYWNKKDSV
                     FGFKNDLALVRLKEKLTAVSPVEVVSESTSITKGDKVSVYGFPDGRLSPVLDSEVVAT
                     TDFGSGIEGISYGGTKPGASGGGLYNDKGSLIGVHQNGVVGSRSGGLVLSKEQLDWVR
                     SYIEGKPKAPVYVTDNILVDEKDKDKLPSTSKEEKPTTPKVESDKDKPNTPLKPQEKP
                     KTEVITSYEGDSTLEVGKERTEETEGEKEGVSLIYRTVYKGTKSKTEMSPIAFDTVYQ
                     GDETKELGFRSVLEGKEGLVTRTTSYQVDKYTGAVSSKISEEKIAPQSQVITLGIKKN
                     SSTKEVPITERFEDSAELEKGKTEVISEGSVGKEVTTVTYKVLPDGKVIENSRTVDVT
                     PMRERVVRKGVKEVVSPDKVESLVPKDAPIREEQPALSEGFSESDALVSGEKIQGDLG
                     ILIVSSEELVPERVEVPDFVTKVTGGEKLTVEGHRNESKIKTPSKQERSSRPETTAQF
                     TTNGTGSSSLTAVFGGKTDKILLSTVEHSVIKHNQQRGWHKINNQWYFRNSDGKERTG
                     WMKENDAWYYFDTNGTMQTGWLEDTDGNWYYLNDNGRMEIGWFQDSSGAWYYLGSSGR
                     MESNTWIYYKGKWYYIDALGKLLFNSVTPDGYRVNEYGEWIN"
     gene            complement(4776..7659)
                     /locus_tag="VU722_000372"
                     /pseudo
     CDS             complement(4776..7659)
                     /locus_tag="VU722_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285043.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
     gene            complement(7775..8002)
                     /locus_tag="VU722_000373"
     CDS             complement(7775..8002)
                     /locus_tag="VU722_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771420.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            complement(8855..9811)
                     /locus_tag="VU722_000374"
     CDS             complement(8855..9811)
                     /locus_tag="VU722_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU1771421.1"
                     /translation="MKNPALLEEMKIYLGRDEVPEDVDAFWDEEVKKVSTLPAYQLEE
                     INFHISQVKCYELTFEGSKQGKVYARVVLPKSEEKVPLIFHFHGYMGRGWDWADMLAF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIIASLPQVDEKRLSSYGASQGGALALVAAALNPRIQKPVAIYPFLSDFRRVLEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMAILAHRIKGEVKMITGLDDDVCYPITQFAIYN
                     RLTCDKAYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(10132..12147)
                     /gene="recG"
                     /locus_tag="VU722_000375"
     CDS             complement(10132..12147)
                     /gene="recG"
                     /locus_tag="VU722_000375"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU1771422.1"
                     /translation="MNLHQPLHVLPGVGLKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILIDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGKMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVVSYISSIEGWQEDPEWRMIAFHLEKKEHLD"
     gene            complement(12166..13269)
                     /locus_tag="VU722_000376"
     CDS             complement(12166..13269)
                     /locus_tag="VU722_000376"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU1771423.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKEIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(13259..13627)
                     /locus_tag="VU722_000377"
     CDS             complement(13259..13627)
                     /locus_tag="VU722_000377"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU1771424.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(13666..14697)
                     /locus_tag="VU722_000378"
     CDS             complement(13666..14697)
                     /locus_tag="VU722_000378"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU1771425.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(14699..15730)
                     /locus_tag="VU722_000379"
     CDS             complement(14699..15730)
                     /locus_tag="VU722_000379"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU1771426.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYARRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(15811..18324)
                     /gene="secA"
                     /locus_tag="VU722_000380"
     CDS             complement(15811..18324)
                     /gene="secA"
                     /locus_tag="VU722_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU1771427.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(18470..18757)
                     /locus_tag="VU722_000381"
     CDS             complement(18470..18757)
                     /locus_tag="VU722_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771428.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFFPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(18768..19418)
                     /locus_tag="VU722_000382"
     CDS             complement(18768..19418)
                     /locus_tag="VU722_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1771429.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(19422..20063)
                     /locus_tag="VU722_000383"
     CDS             complement(19422..20063)
                     /locus_tag="VU722_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771430.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FLDYTRKRLVVISKFFTQDLFVWFLGLLPIGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            complement(20056..20847)
                     /locus_tag="VU722_000384"
     CDS             complement(20056..20847)
                     /locus_tag="VU722_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771431.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLTLVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPITIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAIAYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(21032..21367)
                     /locus_tag="VU722_000385"
                     /pseudo
     CDS             complement(21032..21367)
                     /locus_tag="VU722_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21507..21842)
                     /locus_tag="VU722_000386"
     CDS             complement(21507..21842)
                     /locus_tag="VU722_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771432.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(21933..23243)
                     /gene="der"
                     /locus_tag="VU722_000387"
     CDS             complement(21933..23243)
                     /gene="der"
                     /locus_tag="VU722_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU1771433.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIHEQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(23257..23970)
                     /locus_tag="VU722_000388"
     CDS             complement(23257..23970)
                     /locus_tag="VU722_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU1771434.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(23967..24863)
                     /gene="dnaI"
                     /locus_tag="VU722_000389"
     CDS             complement(23967..24863)
                     /gene="dnaI"
                     /locus_tag="VU722_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU1771435.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKQASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEELELHFAKGKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(24864..26033)
                     /locus_tag="VU722_000390"
     CDS             complement(24864..26033)
                     /locus_tag="VU722_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU1771436.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLRHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPISSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKNQAQKSSTPSPAKSNVPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(26034..26507)
                     /gene="nrdR"
                     /locus_tag="VU722_000391"
     CDS             complement(26034..26507)
                     /gene="nrdR"
                     /locus_tag="VU722_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU1771437.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            26647..27012
                     /locus_tag="VU722_000392"
     CDS             26647..27012
                     /locus_tag="VU722_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1771438.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     SVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            27017..27712
                     /locus_tag="VU722_000393"
     CDS             27017..27712
                     /locus_tag="VU722_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771439.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            27729..28496
                     /locus_tag="VU722_000394"
     CDS             27729..28496
                     /locus_tag="VU722_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771440.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(28849..30048)
                     /locus_tag="VU722_000395"
     CDS             complement(28849..30048)
                     /locus_tag="VU722_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1771441.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETLLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(30045..30938)
                     /locus_tag="VU722_000396"
     CDS             complement(30045..30938)
                     /locus_tag="VU722_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771442.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            31055..31135
                     /locus_tag="VU722_000397"
                     /pseudo
     CDS             31055..31135
                     /locus_tag="VU722_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            31645..31833
                     /locus_tag="VU722_000398"
                     /pseudo
     CDS             31645..31833
                     /locus_tag="VU722_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            32248..32865
                     /locus_tag="VU722_000399"
     CDS             32248..32865
                     /locus_tag="VU722_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU1771443.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQMI"
     gene            complement(32908..33795)
                     /locus_tag="VU722_000400"
     CDS             complement(32908..33795)
                     /locus_tag="VU722_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1771444.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLAYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(33944..35881)
                     /locus_tag="VU722_000401"
     CDS             complement(33944..35881)
                     /locus_tag="VU722_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEU1771445.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIVFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGDAVIEVKI"
     gene            complement(35876..36002)
                     /locus_tag="VU722_000402"
                     /pseudo
     CDS             complement(35876..36002)
                     /locus_tag="VU722_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915902.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator T protein"
     gene            36257..37711
                     /locus_tag="VU722_000403"
     CDS             36257..37711
                     /locus_tag="VU722_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU1771446.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWEQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFIEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNCSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSHAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            37692..38657
                     /locus_tag="VU722_000404"
     CDS             37692..38657
                     /locus_tag="VU722_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1771447.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(38693..39967)
                     /locus_tag="VU722_000405"
     CDS             complement(38693..39967)
                     /locus_tag="VU722_000405"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU1771448.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEQDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKHVGGFT
                     AQVHQRQMIGQVSLYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSSQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(39967..41139)
                     /locus_tag="VU722_000406"
     CDS             complement(39967..41139)
                     /locus_tag="VU722_000406"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU1771449.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKNLPQEKKDLLQNHFDHSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTDLSVADYEKVFFEEVDLDETNSAQFAGYENQYFALVEILDHQRRYSKVEK"
     gene            complement(41270..41518)
                     /locus_tag="VU722_000407"
     CDS             complement(41270..41518)
                     /locus_tag="VU722_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771450.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QEFVDEMGRTYSGNLILQELITVNEAYKATYIGELYIN"
     gene            complement(41586..42210)
                     /locus_tag="VU722_000408"
                     /pseudo
     CDS             complement(41586..42210)
                     /locus_tag="VU722_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(42272..42721)
                     /locus_tag="VU722_000409"
     CDS             complement(42272..42721)
                     /locus_tag="VU722_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU1771451.1"
                     /translation="MTLTTFLLQAVASLLAIITFLIVLNVQRSMLLPGGILGMAVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGIASGTVILRLYHYIKTHRVS"
     gene            complement(42723..43481)
                     /locus_tag="VU722_000410"
     CDS             complement(42723..43481)
                     /locus_tag="VU722_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU1771452.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSIMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGMIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(43596..45575)
                     /gene="pknB"
                     /locus_tag="VU722_000411"
     CDS             complement(43596..45575)
                     /gene="pknB"
                     /locus_tag="VU722_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU1771453.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVMKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRKSSDVIAELKEKKVPDNLIKIEEEESSESEPGTIMKQSPGAGTTYDVN
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVSTAPAGTAE
                     GTVVEQSPRAGEKVDLNKTRVKISIYKPKTSSATP"
     gene            complement(45572..46312)
                     /locus_tag="VU722_000412"
     CDS             complement(45572..46312)
                     /locus_tag="VU722_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU1771454.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(46327..47640)
                     /gene="rsmB"
                     /locus_tag="VU722_000413"
     CDS             complement(46327..47640)
                     /gene="rsmB"
                     /locus_tag="VU722_000413"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU1771455.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKA
                     LVTELVYGTVARRLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(47633..48568)
                     /locus_tag="VU722_000414"
     CDS             complement(47633..48568)
                     /locus_tag="VU722_000414"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU1771456.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(48581..50977)
                     /locus_tag="VU722_000415"
     CDS             complement(48581..50977)
                     /locus_tag="VU722_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU1771457.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDEEEMEQDLKDIAEVLDFSPVLTQEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHVQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGTLDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLCYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGLTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(51043..51357)
                     /locus_tag="VU722_000416"
     CDS             complement(51043..51357)
                     /locus_tag="VU722_000416"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU1771458.1"
                     /translation="MMLKPSIDTLLDKVTSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(51382..52008)
                     /gene="gmk"
                     /locus_tag="VU722_000417"
     CDS             complement(51382..52008)
                     /gene="gmk"
                     /locus_tag="VU722_000417"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU1771459.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVVAQRIEKAKEEIALM
                     REYDYAIVNDQVSLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(52138..53751)
                     /locus_tag="VU722_000418"
     CDS             complement(52138..53751)
                     /locus_tag="VU722_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU1771460.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERRKEAE
                     LERIGALSQAEARDIILAQTEENLTKEIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(53875..56862)
                     /locus_tag="VU722_000419"
     CDS             complement(53875..56862)
                     /locus_tag="VU722_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEU1771461.1"
                     /translation="MANLGLKERYDFQQWIIKDLRDKNDYIQRDATCYDPRLAMDVEL
                     LWDFLMETQEETMDYLLKKLSKETIVNLINKEIVKGGFLFALKEGVFIENKQLRLLYR
                     KPATSFNEKAVQQYQVNCLSIMEEVVYEESDRIDLVIFINGLALFAIELKFNPSGQSV
                     QDAIRQLKGRNPKNRLFRFEQGVLASFAVDTLEVYMTTQLKGQETYFLPFNVGKGEGI
                     EMGSGNPHNPDGVDTDYLWLDVLTKDSILQLIDSFIFFEMDEMDKHNSKKKTLIFPRY
                     HQRRAVSRLLEDMKVNHTDSNYLIQHSAGSGKTNTIAWLAHSLVSLHDEQNQNIVDTV
                     LIVTDRIVVDRQLQEAVKEISHKPGVVKVMGDKETSSDLADAIAGNTKIIATTIHKFA
                     QINQSNWMSVGNTAKKKFAILIDEAHSSTTGSYMSSVSQVLTETDTEDGTIDEIQEVS
                     VADAIEQEIARTGKQDNVSIIAFTATPKATTLQLFGTTQADGSKAPFDVYSMKQAIEE
                     GFILDVLDNYTTYKTYYKLNKAVEEDPELKTTLAKRKIAKFVELSDENINQKVEIIMD
                     HFISHDIMAELGGQGKAMIVTSGREAAVKYQLAFQKYFKDHSITSIGTLIAFSGKVDY
                     QGSEYTESQMNQVKEDYLKDHFDTEDYQILIVANKYQTGFDQPKLVAMYVDKKLRSVA
                     AVQTLSRLNRIYRGYNKRTFILDFKNTYDDIRSAFSPYYRETILADTVTPSDVLTLDR
                     KIDEYGILDSDVIHEFNQFLYQEKRNSREKQKMVSLLNQGYDRVRRFDEKEQLSIRKV
                     IRGFLRMYTFLIQATAYQNEVLHERYNYLQSLVKMIDVRIGGDDFTIADKIVVDYMKH
                     KQTGSFRSVSELEYHPELILTKPSTGGVTTDQEKRLSEILDEINEQLDLDIDPQVGLS
                     GAVSIRELMKKNPRLKQSARVNSREDFVFAFEEEIDNALIEGYSQSQDLFGALLNNDS
                     FKKRLADIFIDDVFKSLKGSEEV"
     gene            complement(56970..57971)
                     /locus_tag="VU722_000420"
     CDS             complement(56970..57971)
                     /locus_tag="VU722_000420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771462.1"
                     /translation="MVEIYAIGWQVGRGKSLGKLKNFRKVISDEASNYIGNIQFANNQ
                     NSNESTLTLKEKFEESIESLQNVETNGNNTEVPFYRKIDESLQSEIDRIQLVSSQLET
                     DLPPLKNFEDIRLYLVCEEIDGVQYKYFLKSIRVAKLKTRFIATLTSGKVKIVDIEKD
                     EGRSLPFIISYAEKTENNETIQYIFDVQDYEIMFGLNESKIITAEENYKKFLSHNFKL
                     STDFKVKVSDEESEKIKAKLKSHRKLINLLAKYNDEASSYEWKCVKRANKLSAQFFQT
                     PFTFNEKSKEIYLTAESLEAFISVITNAKKLGIAKNEYEDSLADKRQKDKKDNIEVQ"
     gene            complement(58007..58657)
                     /locus_tag="VU722_000421"
     CDS             complement(58007..58657)
                     /locus_tag="VU722_000421"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771463.1"
                     /translation="MLFGTDLKFRLAYFFTAFFPAFLLIYFSLVDIHHFLLKETESLP
                     CYLSRNLWHFLMLSVLLSIMLISIYSIRGYINGRRSEENIVKNIVLNFNVFKVTLKNN
                     SQGKVIDIQDGPKINPGFISFVSSTIVPSLVLKFMNGVSALVAIIIIVFFFVLLMLSN
                     DIFPNLILPIFGVNLLVTKDNYNIFFFRKDSAAFSGVKRICTLGNTGTMARTFVFF"
     gene            complement(58660..59931)
                     /locus_tag="VU722_000422"
     CDS             complement(58660..59931)
                     /locus_tag="VU722_000422"
                     /inference="COORDINATES: protein motif:HMM:NF013579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1771464.1"
                     /translation="MTRMKESGIDWIGQIPEEWVISKIKFTTQLNGRIGWQGLTSAEY
                     KEEGPYLITGTDFYNGAINFETAVHIDEKRWSEASQIQVENGDLLITKDGTVGKVAII
                     SGLDDKASLNSGVLRIQTVDEIDRKFLYLVLLSDEFWMWFNYTNSGASTILHLYQNVF
                     DEFTFTFPSKNEQQKIADFLDKKTAQLDKVKALLEEQIQKLKDYRASLIYETVTKGLD
                     KNVPMKDSGIDWIGQVPEGWEISKIRYLVTTRSEKRITDSSIPYIGLENIESQTGKFV
                     ETGIQVDKSENIVVEIGDVLFGKLRPYLRKYWRATFPSTASSEFLVFQSSELDMNFLY
                     YAIQSDSFIEEVNTSTYGSKMPRASWEYIKNMKITFPSSLVEQQKIANLLDENTAQID
                     NLIQIKNQQIKNINKQRQTLIYDYVTGKRRV"
     gene            complement(59924..62032)
                     /locus_tag="VU722_000423"
     CDS             complement(59924..62032)
                     /locus_tag="VU722_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009659312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU1771465.1"
                     /translation="MSSFKEKLPLFQANDIQISNDVNTVWSIANTLRGAYRADKYRDV
                     IIPMFVLTRLEAALLPTKDQVVAQYKANPNTPEKVLEKLSGYRYYNVSPFTLENLQND
                     PNAIEENFIAYLDGYSCRVKDIIENLKFKEQVRTLAQSGRLFTVIKKFSQIDLSPSSV
                     DSMRMGYMFEDIIRRFSENEEAGSHYTPREVIALMVNLLLIEADEELFVDKKELKILD
                     MAAGTGGMLATAKSYIRQLNTGATARLFGQEVLPETFGIGRADMLIRQEDSDYFVKVD
                     TLKDPDPFPDTKMSFVIANPPFGQAWGGKDADDGVEDAVKKDHQLFDKTEGRQGRFVA
                     TPGTGDAQLLFHLHALTKLEENGRAAIISNGSPLFSGGTSSGESQIRRYILENDLLEA
                     IVALPGQFFYNTGIGIYIWIYNKNKSPERQNKVQFIDATEEFIPLRKSLGQKRRELSQ
                     DNIRQILRWYDDFQENDHVKIFENQEFLYREFTVMQPLQRRGQISEETIEKAKSVPFL
                     AKLFDEYKYQELLEMEPRSAKDEKKLQDFVAGKIKQEAILTALAKGSSDKTYPDFENF
                     VQVIKDLLGEFKLTPANINALALAMSEMDKTAEVIRTKKKDKANEIADGIVYDKTTKD
                     SEIVKLTEDVETYFAREVYPHVPDAHYWFDEEKGYGAEIPFTRYFYQYQEPESAEKLL
                     AEFYALEAELQTLLEELKHD"
     gene            complement(62248..62502)
                     /locus_tag="VU722_000424"
     CDS             complement(62248..62502)
                     /locus_tag="VU722_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEU1771466.1"
                     /translation="MLLKFTEDAWADYCYWQTQDKKTLKRINKLIKDIQSDSFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSIAFLSFKDHY"
     gene            complement(62506..62760)
                     /locus_tag="VU722_000425"
     CDS             complement(62506..62760)
                     /locus_tag="VU722_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU1771467.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIVQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(62892..63989)
                     /locus_tag="VU722_000426"
     CDS             complement(62892..63989)
                     /locus_tag="VU722_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU1771468.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLEQAEGLKVVAMSGNFMQRGEPAI
                     IDKWIRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDTLAFGTEEVLD
                     YQKIADLYTEQEAEMEKFVEKLPDSLSYPQKTQAMWKEFADLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVDKDVDFASATALRQHQSDQDFLERFMPSVALFEQA
                     SKVSWDDYFPMLRYQILSNSDLTTIYQVNQEMAVRIKEAIKPAQSVEDLVKVVATKRY
                     TKARVRRLLTYILVQARESDLSEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDT
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(63999..64745)
                     /locus_tag="VU722_000427"
     CDS             complement(63999..64745)
                     /locus_tag="VU722_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU1771469.1"
                     /translation="MIMATYETFAAVYDEVMDDSLYDKWTDFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRAASAKQKIDFMEGNMLDLSKAGQ
                     YDFVTCYSDSICYMQDEVEVGDVFQEVYNVLNEDGVFIFDVHSTYQTDEIFPGYSYHE
                     NAEDFAMLWDTYEDAAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEVLTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSARWFFVAQK"
     gene            complement(64958..65308)
                     /gene="rsfS"
                     /locus_tag="VU722_000428"
     CDS             complement(64958..65308)
                     /gene="rsfS"
                     /locus_tag="VU722_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU1771470.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIADNIREKVAQAGFKGSHIEGDATGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEAHSVDLSETL"
     gene            complement(65309..65902)
                     /gene="yqeK"
                     /locus_tag="VU722_000429"
     CDS             complement(65309..65902)
                     /gene="yqeK"
                     /locus_tag="VU722_000429"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU1771471.1"
                     /translation="MAYQDYINCSREALLEKMAELLPEKRLTHCLGVELAAIELAERF
                     GVDVEKAGLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LNLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETVHTVEHLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(65902..66531)
                     /locus_tag="VU722_000430"
     CDS             complement(65902..66531)
                     /locus_tag="VU722_000430"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU1771472.1"
                     /translation="MAIELLTPFTKVELEPEIKEKKRKQIGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIEGLAIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(66583..66894)
                     /gene="yhbY"
                     /locus_tag="VU722_000431"
     CDS             complement(66583..66894)
                     /gene="yhbY"
                     /locus_tag="VU722_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU1771473.1"
                     /translation="MSLTSKQRAFLNSQAHILKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(67108..68214)
                     /gene="yqeH"
                     /locus_tag="VU722_000432"
     CDS             complement(67108..68214)
                     /gene="yqeH"
                     /locus_tag="VU722_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU1771474.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFISGNDV
                     LLVGNKKDILPKSVKSGKISQWIMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPRTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASTFYDKHLGTLLTPPNSKEKEDFPRLVQRVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVIRKAII"
     gene            complement(68217..68807)
                     /locus_tag="VU722_000433"
     CDS             complement(68217..68807)
                     /locus_tag="VU722_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU1771475.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYMPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIRIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(68759..69667)
                     /locus_tag="VU722_000434"
     CDS             complement(68759..69667)
                     /locus_tag="VU722_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU1771476.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(69724..70284)
                     /locus_tag="VU722_000435"
     CDS             complement(69724..70284)
                     /locus_tag="VU722_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU1771477.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVNPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            70423..71628
                     /gene="sstT"
                     /locus_tag="VU722_000436"
     CDS             70423..71628
                     /gene="sstT"
                     /locus_tag="VU722_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEU1771478.1"
                     /translation="MKRIIHAWNKASLVKRILIGMLCGGILGLTLPNLSGIGLLGDLF
                     VGGLKAVAPILVFALVANALSQHQKGQDSNMKTVVFLYILGTFAAALVAVVASFIVPI
                     EITLNSANTEIAPPDGIGQVLSNLLLKLVDNPVNALITANYIGILSWAVVFGIAMREA
                     SKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGIGSPANYGILLVLLVT
                     TMLFVALVVNPLIAFFFMRRNPYPLVWNCLRVSGVTAFFTRSSAANIPVNMKLCHDLG
                     LNPDTYSVSIPLGSTINMAGAAITINVLTLAAVNTLGIPVDFATAFVLSVVAAISACG
                     ASGIAGGSLLLIPVACSLFGISNDIAIQVVGGGFVIGVIQDSCETALNSSTDVLFTAV
                     AEYAAARKK"
     gene            71696..72547
                     /locus_tag="VU722_000437"
     CDS             71696..72547
                     /locus_tag="VU722_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU1771479.1"
                     /translation="MSISQRTTKLILATCLACFLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFFLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEALK
                     LVYLDHSDHLFHQTDYHIHYFEMRQRQRRILRNMAQQINTCHLAVSESLILAQLFSKI
                     AGQLSQTNPASDLLDEIERYLEVFRNRSLPKTRDEFETRATLLQLLREAKTFIQVKVD
                     FYQKYGQ"
     gene            72690..73070
                     /locus_tag="VU722_000438"
     CDS             72690..73070
                     /locus_tag="VU722_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1771480.1"
                     /translation="MTYLEKWFDFNRRQKEIETLLEDTIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTSD
                     GQKTLASLQKAVETSLETGLDFLI"
     gene            73168..73389
                     /locus_tag="VU722_000439"
     CDS             73168..73389
                     /locus_tag="VU722_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU1771481.1"
                     /translation="MIEITYLDASKNERTVTFDSYEDFDRSQQACLIGVADYYPVQKL
                     TYKGYDLDYHGTYGDVFFYLMKQDLSQYN"
     gene            73405..73719
                     /gene="trxA"
                     /locus_tag="VU722_000440"
     CDS             73405..73719
                     /gene="trxA"
                     /locus_tag="VU722_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU1771482.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTADQIKAIVAE
                     LS"
     gene            74024..74559
                     /gene="queF"
                     /locus_tag="VU722_000441"
                     /pseudo
     CDS             74024..74559
                     /gene="queF"
                     /locus_tag="VU722_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
     gene            complement(74814..75482)
                     /locus_tag="VU722_000442"
     CDS             complement(74814..75482)
                     /locus_tag="VU722_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU1771483.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            75840..76610
                     /locus_tag="VU722_000443"
                     /pseudo
     CDS             75840..76610
                     /locus_tag="VU722_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISSpn10 family transposase"
     gene            complement(76675..77466)
                     /locus_tag="VU722_000444"
     CDS             complement(76675..77466)
                     /locus_tag="VU722_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU1771484.1"
                     /translation="MYQKLLRKIAEEKPSYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFYFIAEGISSDGGLDKDIDKVGLSTLERSFRALIYVNLLSADANQ
                     QSIFYQRLKSEIRNVLLNQGLYYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPN
                     FPKTRVHEVFDILGQLFKRITIRFTDDEDWRLARVLYEPILQGKLEQEQVASWIKIVD
                     FPIEEREDFYKFSNFRSCLSEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(77891..78655)
                     /locus_tag="VU722_000445"
     CDS             complement(77891..78655)
                     /locus_tag="VU722_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1771485.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIAPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWSGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(78648..79334)
                     /locus_tag="VU722_000446"
     CDS             complement(78648..79334)
                     /locus_tag="VU722_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771486.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GKNIETNRRKSKSCLGIVGQEDMLDMTLNVYDNLFAHGLCYGISSVELRKRIGSLLDF
                     VQLSKHAQKMVNQLSGGMRRRLVLARALINRPDIIILDEPTVGLDIQSRNIIWDKLLE
                     LKELGVSIIITSHYMNEIEYLTDRVLMLHQGTIKEEGTVEDLLIKYDADNLETLFLGL
                     TGTEKEDLHV"
     gene            complement(79304..80416)
                     /locus_tag="VU722_000447"
     CDS             complement(79304..80416)
                     /locus_tag="VU722_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU1771487.1"
                     /translation="MNLPKIKDIHSVLFLKDKIRLGIGKDYGIEIENLDEKYTQLIKL
                     LDGQYTINEICSLVDSLSPNEVEESISLLDTLGYLEDNFVTTTELTSEELDRYSVNLN
                     FFNTLDTLSLTKYDYQLKLKKTRILLLGIGGIGSNICLALAELGIGHITAVDFDTVEA
                     SNLNRQILYSTSDIGKRKVEAAKESLRKFNPLIEFEVLDKEIGSKEDVDELIKTSKCD
                     IVVNVADYPTGYIDFWVNEACVQYNKLCLSAVVGKKNGKVYSIIPYKAACYYCQFLED
                     LEKIPEYAEELETVRTMTNSLELEMFRTPNGALGPACLFQGYFISFEILRYIFWGYEA
                     LLTFNKRFSIDFITFEQHFDELTKYPTCSICGGKKE"
     gene            80684..81361
                     /locus_tag="VU722_000448"
     CDS             80684..81361
                     /locus_tag="VU722_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1771488.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            complement(81421..83217)
                     /gene="pepF"
                     /locus_tag="VU722_000449"
     CDS             complement(81421..83217)
                     /gene="pepF"
                     /locus_tag="VU722_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU1771489.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALANLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAQYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(83229..83972)
                     /locus_tag="VU722_000450"
     CDS             complement(83229..83972)
                     /locus_tag="VU722_000450"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU1771490.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(83974..84927)
                     /locus_tag="VU722_000451"
     CDS             complement(83974..84927)
                     /locus_tag="VU722_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU1771491.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTAL
                     AEEDWADNWKKYYAPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNT
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(85062..>85361)
                     /locus_tag="VU722_000452"
     CDS             complement(85062..>85361)
                     /locus_tag="VU722_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1771492.1"
                     /translation="GREGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQ
                     SVFLVGQLTQNQFDSIVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
BASE COUNT        24701 a        19268 c        15660 g        25732 t
ORIGIN      
        1 ctgatgatgc acctgaatct caatgattac ttgagtacca ttatccaact ccgccaagac
       61 gtctatacta gtgtaaaaat cttgagctga gtaaggcata gaaggcaaaa catgaatgtt
      121 acttccctcc aaaatagtca cattttttgc tggcaagtcc agcatatcgc gaataaattg
      181 acaagtgatt tccggattgc taaagatttt cttagcaact aagtcattgg ttgggctgat
      241 gcccggatgt ctgagaatta tccttctcct ccctctatta taccatagtt ttaaatctaa
      301 ttttgctaga ttctatggtt ctatctattt attcggaaaa gaagtgagaa agttaaaaac
      361 tattgaccct aatcacttgc aaagagatat atcttgctca cattatttat taaaagctat
      421 attttacaaa aaagattaca aaatcaacca ttttagaaaa gccttaccac tttctagact
      481 atgaattcta gtgtttttat actcctagct ttctcgtcaa tatgccataa agcaagttca
      541 gttgatccat tccccatact cgttcactct atagccgtct ggtgttaccg aattgaaaag
      601 tagtttaccc aaagcatcaa tatagtacca ctttccttta taataaatcc atgtattgga
      661 ttccatgcga ccagatgatc ctaagtagta ccacgcgcca cttgaatctt ggaaccagcc
      721 tatctccatc ctaccattat cattgagata ataccaatta ccgtctgtat cctctagcca
      781 accagtttgc atggttccat tcgtatcaaa ataataccat gcatcatttt ctttcatcca
      841 acctgtccgt tctttcccat cagaatttct aaaataccac tgattattta tcttatgcca
      901 tcctctttgt tgattatgtt taataacaga atgttcaaca gtagaaagta atattttatc
      961 cgttttaccg ccaaaaacag ctgttaacga tgacgaacct gtcccgttcg ttgtgaattg
     1021 agcagtggtt tctgggcgag atgatctttc ctgttttgat ggagtcttta ttttactctc
     1081 atttcggtgc ccttctactg tcaatttttc tccacctgta actttagtca caaaatctgg
     1141 aacttctact ctttcaggga ctagttcttc tgaagatact ataagtatcc caagatctcc
     1201 ttgtattttt tctcctgata ctaaagcatc tgactctgaa aatccctcac taagcgcagg
     1261 ctgctcttct ctaatcggcg catcttttgg aactagagac tctactttat ctggagatac
     1321 cacttccttc acacccttac gaactacacg ctctctcatg ggtgtaacgt caactgtacg
     1381 agaattttca ataacctttc catcaggtaa aaccttataa gtaaccgtag taacctcttt
     1441 acctacagaa ccttcagaaa taacctcagt tttacctttc tctagttctg cggaatcttc
     1501 aaaacgttct gtaattggaa cttcttttgt gctgctattt ttcttaatac ctaatgtgat
     1561 gacttgagat tgaggtgcta ttttctcttc agaaatcttg gaggataccg ctcctgtgta
     1621 cttatctact tggtaacttg tagtgcgagt aactagaccc tctttaccct ctaaaactga
     1681 acggaaacca agctctttag tttcatctcc ttggtaaacc gtgtcaaagg caataggtga
     1741 catttctgtt ttcgatttag tacctttata caccgttcga taaataaggg aaacaccttc
     1801 tttttcgccc tcagtttcct ctgtacgctc tttcccaact tcaagggtac tatcaccctc
     1861 ataactcgtt ataacctctg ttttcggctt ttcttgcggt tttagaggtg tatttggttt
     1921 atctttatcc gactctactt ttggtgtggt cggtttttct tcttttgaag ttgatggaag
     1981 tttatccttg tctttttcat ccaccaaaat attatctgtt acataaacag gggctttggg
     2041 tttaccctca atataggaac gaacccaatc taattgttct tttgataaga ctaacccacc
     2101 actgcggctt cctacaacac cattttggtg aactccaatt aaagaacctt tgtcattata
     2161 aagaccacca ccagaagctc cgggttttgt accaccatag ctaatccctt caatacctga
     2221 accaaagtca gtagtagcta ctacttcact atccaaaact ggagacaaac gaccatcagg
     2281 aaaaccataa acggaaactt tgtcaccttt agtaatcgaa gttgactcag ataccacctc
     2341 tacaggagat accgctgtaa gcttttcttt caaacgaacc aaagctaagt catttttaaa
     2401 tccaaatact gagtctttct tgttccaata aacaatatca tcatcggaaa aattcacagg
     2461 ctgaccactt ggcaaagtag ctttatacac tgtattggtg cgaccagact tcgtaactac
     2521 ctcagaacct ttaactgtta agaaattatg agcgactgtt aacaccaaat ttggtgcaat
     2581 taaagtacct gaccccgacc catctggcgt ttgaatatgc gttgtagcat agaagttttc
     2641 tgaaccattc ggagcttgta atacctcttt actaggcaca ggtaagttcg atttaccact
     2701 caaatcaacc ttaccaactt cagttcttgc aaaatccgaa gaagacgtag atggaggagt
     2761 taccgaatct actaccgctc ttataattgt atcacccaaa gctaacttac tgacatattc
     2821 atcagaccaa cttgtatcac ttgctaattt gttaattggc actccgttat aggataccac
     2881 tttagctgtt ggagaagttg ctattaactg tttgaagttt ggattttgtc ttaaatgaaa
     2941 attcaaacca cttccaacag aaccttcttg aacaacctta tctgaaatca aaggagttcc
     3001 tttagtatct tccactcgaa gtagaacgcg acctttttct tcaccctcta gtaaagtagc
     3061 tcggcctttt tcatcaaaac gatacaaagc accgtcaatc tcagactcta catcttttaa
     3121 ggctctgtga ttttcatcat agtagtaacg gtttgcacca tctatatacc aaccctttat
     3181 accatattta tcaatcatag aacgaatcca agctctgtgc ttttccgtaa agagggtacc
     3241 accaccaata cgctcacttt cttgagcgtt tggagtattt gtcccatgtt ggtggatacc
     3301 gactacctct cccttatcat taaacaaagg agcacctgaa aaacctccta aagctgagga
     3361 atgataagtg actgtaccac tctctttatt gacactactt acagttgttg taactgaata
     3421 agccttaccg tctttcaatc gtgctttgtt ttctgcactt aaattcggag ttgaaaagtc
     3481 attaggatag ccgaccatag agattttatc accagtagaa acctctttat ggctcaattc
     3541 tcttggtgaa tcttcaccac ctgtcatagc ttctacagtc tttttagtta ccactactgc
     3601 taagtcgttg ctatagtctt tcccaaaatt tttctcatca tacaaatgaa tagagtcttt
     3661 ttcaagagtt tctgatacac cagaagtagg tactttattg tgcttttccg tctctgagtt
     3721 catcacaaca taactacgag cagacgcccc accacgcaag accgcagact tatcctcttg
     3781 gtttttatca tagtagttat gagctactgt taccatcaca ttcggcgcta caaagacacc
     3841 gctacctgat gcggtttgtt ttccacttgt tccgctatca taagtggtat aggtcatagc
     3901 aacaccttcc gcagatttac tatgaacgtt cacatctttt atatcgttac caccctgaat
     3961 aacatcagca gcaacgactc caccaccaat aactggtaag tctggtgcag ctaatccaat
     4021 catactcact aatgccagac atcccaccaa cccgtaagct tttgacttac gatatttacc
     4081 taaacctttt aaatataaaa acatcttttc ctcactttag tttctaatac ttatttatcc
     4141 agatataata gcttataatc ttttaaaatc ttcaaataag ttatgattgt tccatactct
     4201 tcaaaccatg tcatcttcgt cttgccgtat gtatatgtta ctgacttcgt cagttctatc
     4261 tgcaacctca aaacggtgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacg
     4321 gtgttttggg caggctacgg ctagcttcct aatttgctct ttgatttttt gagtataagg
     4381 acatattgga ttctatgtgc tatattgtca acaatacact cttcttcctg tatatctacc
     4441 aacatgaatt acagaatttt attttactat aattttacct atattccaag acaagaaata
     4501 aaataatcaa gaacaaaaac gcatataacc aataactagc tatatgcatt ttaacactta
     4561 aagcgaactg ttaaattgcg actagtagta tccagtcgga agtaagtcgg aaatatacag
     4621 tttatttacg attagcaagt catttacccg gcaatagaag ctcatttaaa ttgatttttc
     4681 cttagagtag aaatctctac gaaaactatc taaataaact tttaatctct atgacgaata
     4741 aaacgtgtct cagttattca tcaacatcca agtctctagt agttgaccca ctctccattg
     4801 gagttaactt gataaccatc cactatggta ttaacagcta atcttccgct ttcattgaca
     4861 tagtaccatt tgtctccaac ttggaaccat tgatttaccc tcattgcacc agatgattcc
     4921 tgatagtacc aatggtctcc atcttttatc caaccagtcg ccattgaacc gttagaatgg
     4981 agatagtacc acacaccact ggattcaacc cagccagtag acattgctcc actctcactc
     5041 aaataatacc attgattacc atctctgacc caaccagttg ccatcgcacc agtagaactc
     5101 aagtagtacc atttatccgc ttcctgatgc cagcctttca ccacttcacc agcagatgta
     5161 taaaaatacc acgcaccatt ttcttgcttc caaccagtcg ttattggaac tttagtctca
     5221 gttttaataa catctcctac ataagattgg aggtaacgag gagcaaaaga agtaagagga
     5281 gagtttgcta ccattctatc tgaagactcc aaagataatt tatccttctc tgacttcctt
     5341 tctgtcatct cctcagatac attttctctt actgtattca tggtctcgac aggattttct
     5401 ttcgcatctt caggaattct actaccagct agtgtaactg gtaaatcatg catactgtca
     5461 attctaccgg ccattagacc tgtaatttct tgacctgcat cttctttatt aaaggtgaaa
     5521 agtagagttt tttgatctgc ttgggtcaag aaggtagctt tgtgtccatt cgctaaagtc
     5581 aaagtcggaa tagcattcac tagtacctca gaatcaaatt gcatagctaa gatgccttgt
     5641 tctgcatcct cttcttctgt ttccaattta cgaacgtccc tgatagttac actcgttgga
     5701 tataccggct cctttgttaa aaagtcccaa ttaaattttc taaatgatag ggtatagtca
     5761 ttttgtcctt tttcagtatg ttcatacaag ataccatact ccccatttcc taattcttga
     5821 agcgaattat aggcaaactc tcctttttga attggtctat gatgtaaccc aagtcaagtc
     5881 tccgttgtcc tctacacgag ccaaatgagc cattccattc gtccgtttag gtcctcctga
     5941 attggttaaa atgatatatt cttttccttc gtgcatggtg tgaatagcag ccatttggac
     6001 ataaacatct ttaacctgat tatatctctt gatttccttg tcccaagttt gcccaccatc
     6061 tttacttgtg gcaacctgta aatcacccgt taaccctctc ataaagagtt tcacatcacc
     6121 attatttaac tgcacagcaa ctgactcagt attttgggca ttcctattat tcatagttga
     6181 ggaatgaatt ttccttctgc ctaccgtcct atcatcatta acagcagctc cagcctgcca
     6241 tgtttctcca tgatcatctg aataaatcaa acgtgaagac tgggagccgc ttagatggga
     6301 gatagcattg gtggtataag tgggaactag gatacgtccc ttgtgctctc ctgttctaag
     6361 cacaattcct gtacctggac ctgttcctaa aaatttcatc caatcttggc gaattgatgg
     6421 tgtaatatct cttggttgcg accaagcttt cccatcatca tcactatagg aaagccacaa
     6481 atagctcgta taggctacac gaaatggagt tttagcagat tgagcaaagt agatattccc
     6541 aagaagctct tctcctttat agaggtcgcc cttatctcta taggcttctt cttttggatc
     6601 cactacaacg cgataatctg ttttttgatt atttgcatca tatacttctt cgttttctcg
     6661 aacagtatat gcttgatttt ccccttgttt atatagtaat tgatagtgct tgtctccaac
     6721 ttgttgataa gctttttgag gtttgtttgg cattccaaag acagctcgac cctctggaaa
     6781 catatcgtag attgaaaaaa ttctctttgt ggtaggatct tgaaccaaga ccatatcgat
     6841 attaagtgga gatgatgcct gcggatcttt tgcttctgga ttgtctcgca ggttggtcaa
     6901 ggttaaggtt ggctgccaag tagttccccc atcctcactt ctcctaacga ccatagcaac
     6961 atctccccaa tcagaatggt ggagacgacg ctgatctgcc cctgccagta atgttccttt
     7021 atccgtacgt agcaaagctg gaatccgata actcttaatt ccctcactat ttggcttacc
     7081 attgacatca ctcataaaca actcttgctt ctctgtcaag actgcccctt cagcaagtaa
     7141 aggctcaata tctatcacat caaacaactg gctacgtttt ttgacttcct ctggagttag
     7201 agcacgattg tatacagtca gattacgaat agaaagatct gagctccact tcagttctcc
     7261 tgctctatta gttgcaccta actggagttt atctacatct ggcatatctg ccaggaattt
     7321 ccctgacttt ttattcgtac gagataatac accattcaca taaagacgaa cctgaccatt
     7381 tggactatcc tttcttggtc tttcaacagt aaaagtaacc gaattatact tgcctggtct
     7441 aatcttcaaa ggcgcatctg tataacttcc ataaaattgg ctaccatcag ctccacgtcc
     7501 ctctatcaaa gctgtcccat tattgattgc cattgtaaag tattcattta ctttagttgt
     7561 actggaagca gaaaagagat tgtaaaaact aggaccatca gcagccggtt tgaactccac
     7621 atgaacagtt gcattttgga gtccctttac tttctccaat cagactcctg ccaatctagt
     7681 ttatctacca ggacaccgct gcaattaaac taaaatatct ctttataagc aaatgatgga
     7741 catcagctta tgctatttac accatacttc ctgctcaatc cttatcgaac actttttcaa
     7801 atagcttttc ataagcataa atacttgtag aaataatggg aaatataatc aagctcacaa
     7861 tcagaatctt atccagctta aaggggacaa tcccaaataa gtgaagaaat aaatcaatca
     7921 gaaaactgtc gaaaaaaact gtcaaaagta gttcaacttg tctttttctc tgcttttttg
     7981 tcttgaatgc cttaaatatc atattattcc ccttttctaa gcttcaatcc cttctctcta
     8041 tctgttattt cgcatagcta ctactatttt tacagcaatc tatctttaaa tatacataaa
     8101 gatagattct atcacttttt ataagtgtta gtaaatttat tatacctcat ttttaaaacg
     8161 ctttcaatat agtgtagtat agtagatttt agtttcaaaa aactctttta tataataatg
     8221 tccttgaaag tagtttcagc tgaacattta tagttcataa aaagaaaaca gaaactcatc
     8281 tgttttttta cactcaatga aaatcaaaga ccaagctagg aagctagccg catgatgctc
     8341 aaaacactgt tttgaggttg tagataagac tgacaaagtc agctcaaaac accgttttga
     8401 ggtggcagat agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
     8461 tgacgaagtc agtaaccata cctacggcaa gacgaagctg acgtggtttg aagagatttt
     8521 tgaaaagtat taacacctac agacaagcct gacgatagca agaactaccc tactcgatag
     8581 gtatcggctt ttgctttctg aaaaaaatta ttttaagcaa tttgacaaat ctagcaacaa
     8641 aaaattctat aaatataata tattgaaact agaatagtac acatctactt ctaaaacatt
     8701 gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttgtttca ttttactata
     8761 tttccatgat aaaacgcata gtatcaagtc ttcttaatcc cctgatacta tgcgtgtttg
     8821 tgatttttaa gattttgtgc ctagagtcga ctccttattt tagatatttg aaaggaatct
     8881 cactcccaca gagccagtta taaacctggt cattgacaaa aacattcatg gcttcatggg
     8941 catactcagg catgatgcga taagccttat cgcaggtcaa acgattgtaa atcgcaaact
     9001 gggtaatggg atagcaaaca tcgtcatcca aacccgtaat catcttaacc tcacccttga
     9061 tacgatgggc aaggatcgcc atgatctcct cctcagtttc atggaagggg tcgtaaaatt
     9121 tgaaatatct aaaaagttcg tcataggctt cgctagtatt accaatctca agcactcgtc
     9181 tgaagtctga caagaaggga tagatggcaa ctggtttctg aattcgagga ttgagcgctg
     9241 ctgcaaccaa agctagagcc cctccttgcg aggcaccata gctggaaagt cgcttctcat
     9301 ctacctgagg cagactagca ataatttcaa ccaactggta aatgtccaga taaacatcct
     9361 tataaaagag gtggtcccga ccttccacag caccacggat gatatgtccc ttaacggtat
     9421 ttccaagagg agagcgcaaa ccgtcttgtg aatagcccga ctggcctcga acatccatgg
     9481 aaacaacacc gtaaccagct acggtgaaag ccagcatgtc ggcccaatcc caaccacgtc
     9541 ccatataacc atggaaatgg aagattaacg gaaccttctc ctcactcttt ggaagaacaa
     9601 ctcgtgcata gaccttgcct tgcttgcttc cttcaaaggt tagctcatag cacttgactt
     9661 gagaaatgtg gaaatttatt tcctccaact ggtaggctgg aagcgtggaa acttttttca
     9721 cttcctcatc ccagaaagca tcaacgtctt ctggaacctc gtcccttcct agatagatct
     9781 tcatttcttc taacaaagct ggatttttca tagcatgctc cttttgtttt gtaatcgcta
     9841 gcaccactgt agcacatcta agaaagcaat gcaagaaaga agggtaaata gaaagtgaat
     9901 ttagcttttc ttccttcaag cctattgact gaaagtagtt ttagaaacga aaaaagagca
     9961 tttccgccct ttttcttctg ctcaatctta atctgttgct tctttctttt gaaaagtgct
    10021 tgggtaattt actttaatcg ttactgtcat atgagagtcc tcgtttcttt ttgatgactc
    10081 tagtataagg gccaaacctg aaagctagct taagttttcc ttagagaaag cttaatccag
    10141 atgttctttc ttttccagat gaaaggcaat catgcgccac tctggatcct cttgccagcc
    10201 ttcaatagaa ctaatgtaac taacaacttt tctagcttct tctaaaatcg gaaaatcttc
    10261 gataatatca gccacttgga actctggaag tcctgactgt ctggttccaa aaatctcacc
    10321 agaaccacgc attttcaaat cttcctccgc aaggacaaat ccattggtcg tttctgtcat
    10381 gatgcgcatg cggtctttcc cagaatccgt cttgggattg gcaacgagaa cagcgtagga
    10441 ctgcttgtcc ccccgaccga cacgacctct gagctggtga agctgactaa gcccgaagcg
    10501 atcggcatcc atgatgatca tgacagtcgc atttggaaca ttgaccccaa cctcgataac
    10561 cgttgttgaa accagaatat ctgtttttct ctccttgaaa tcctgcatga tctggtcttt
    10621 ttcgtcactc ttcatcttac catgtagaag agccacttct gccttacctg caaaatgagc
    10681 cgtcagctct tctgataagg caatggcatt tttcaaatct agagcttctg attcttcaat
    10741 caaaggagag atgacatagg cttgggaacc tttttgaatt tccccctcta accaagtcaa
    10801 gacctgaggt agttgctcat gtttgatcca gcgcgtcaca ataggtttcc gacctgctgg
    10861 catctggtcg ataatggaaa catccatatc tccaaaggct gtgatggcaa gcgtccgtgg
    10921 aatgggagtc gccgtcatca tgaggacatc tggattgtcg cctttttccc gtaaaatacg
    10981 cctttgcccc acaccaaaac ggtgctgctc atcgataata atcaaaccaa gacgagcata
    11041 ctccacccca tcttgtatca gagcgtgagt tccgataatc aaatcagcct cacccttggc
    11101 aatggtctcc aagacttctc tcttttctgc agctttcaag gaacctgtca agagagccag
    11161 tttcaaattg ggaaaaaggt tctgtaaact ctcaaagtgt tgctctgcga ggatttctgt
    11221 tggtaccatt agggcagcct gataacctgc tgtcactgcc gcaaacatgg ccaagccagc
    11281 gactaccgtt tttccgctcc ccacatctcc ttgtaggaga cgattcatgt ggtggtcgga
    11341 cttcatatca attaaaattt cctgcaaact cttttcctga gcttgggtca gggcaaaagg
    11401 aagacttgct ttaactgctg tcactttttc ctgagaccaa ttcagaacca gaccacttcc
    11461 ctgaactcta ttttcagact tgagcgtctg caactgcatt tggaaataaa agagttcctc
    11521 aaacttgata cggcgaagag cctgcttgta ttctgccaaa tcctttggaa aatgcatagc
    11581 tcggactgcc tgacaacggg acatgagttt gtatttgtct agtaaagact ggggcagatt
    11641 ttcttctatc aagaggtcca gtccctgatc aaaagccgtc ttgatgacct taaccagact
    11701 ggcctgactg attccctgag ccagacgata gacaggctgg aggtcatctt ctacctgagc
    11761 cagaaccttc atcccagtca gactagcctt agcgcggtcc cattttccaa agacagcaag
    11821 ggttgctccc aactctattt tatcagccag atagggctgg ttaaagaaat tcaccgcaaa
    11881 aacgacctct ccctgcttga gactaaaacg caggcgattg cgcttgaaac cataatactg
    11941 gacactagca ggagtcacta cctgaccaga aagaactgcc ttctcaccgt cttccagctc
    12001 cagcacctgc ttggttttga agtcttcata acggaaagga aagtagagca agagatcttg
    12061 caagttttca attcctagtt tggcgtattt ttctgctgac tttagtccca caccaggtaa
    12121 gacatgcaag ggttgatgta gattcatgct ccactccttt cttttctaat aatattctct
    12181 cggaatacgg tcgctgagga ggcaaaccac ctcatagtta atggttacgc ggtaggtcgc
    12241 tacctgagtt gcagtgattt ccttatcccc attggagcca atcaaggtta ccttggttcc
    12301 gagtgggtaa ggcttaggta atcgaatagt gatttggtcc atcgaaaccc tgccgacaat
    12361 tgggcaagct tggccatcta ccaagacaga gaaattctgc atgtctcttg tccatccatc
    12421 tgcatacccg attggcacgg tcgcgatgac ttgctcgcta tccgcttgat aagttgctcc
    12481 ataacccatg caagctccag ctggaactgt cttgacatga accagagcag actccaaggt
    12541 caaggccggt atcaaatcat aaggcaaatc caagaccgct ccacttggat tgagaccata
    12601 catggcatct cccatacgaa ccgcattgaa aatagtctct acatgccaaa gagtcgttgc
    12661 agaattgcta gcatgaacca gctctggaac ttccttcata ctagctaaaa tagttttaaa
    12721 ccgttctaac tgggcattaa aatagtcatc tgattcctca tcagcagtag caaagtgggt
    12781 aaagattcct tcaacacaaa caccgtgttg ttggagcaaa tcttgagcct gctcaacctc
    12841 actggcctct ctaaaaccaa tccgtcccat ccctgaatca atcttgaggt ggactgtcaa
    12901 tccagttagg tccacttcct tatctaagag tgcttgaatc cactccagtc cagccactgt
    12961 caaggtgaag tcatattctt tagctagagc aacagcttcg atttcagaaa ctcctaaaat
    13021 gaggattggc ttgctgagtc cagcttgtct gagttcaatg gcttcatcga tattggaaac
    13081 gcaaaagcca tcaacatcat cttgaatttc cttggcaacg gcaacagctc catgaccata
    13141 agcattggcc ttgaccacag cccacttgag cgttccttga gggatatgag cccccatttg
    13201 ctgaatattt tgtcgaatag ctcccagatg aatcagaacc ttggttggtc tatgtggact
    13261 agctttcatg attttcctcc aaaatgacac tggctgtcac aaactgatcg gtgtggctga
    13321 tagacagcca aatctttcct gaaaatggtg cctgactaaa ataaggcgcc ccacgttcat
    13381 tgttcaagac ttccaaatcc tgaaaaccga gcttgctaat gcccgttccc atagccttgg
    13441 aaaaggcctc cttagccgac cagcgaccag ctaaatattc tatttgcctg cgtcctttga
    13501 gactggtgaa gcgctccatt tcctgagcgg tcagtacacg cttagcaaat ccttcatgtc
    13561 gtgtaactgc gctttctatc gaagccaatt cttcgatgtc aattccgtgt ccaactatca
    13621 ttctcatcaa aaggagttga gattccccaa ctccatcctt ttcacttatt ttgtcaaggt
    13681 aacataaatc tcttctacca aggcctctgt attttcccaa cctaggcaag ggtcagtaat
    13741 agagcaacca aagacctctg gttggttttg acgaccatct gctaggtaag attcaatcat
    13801 aaatcctcga accgtctttt taattttctc attccaatca cgattctgca aggtctggcg
    13861 aacaattcga atctgctcca tatattgctt gcctgagtta tcatggttgg tgtcaatgag
    13921 gataaaagga ttttcaagtc ccatggtttc atagcgttca atggcttgga gtaggttttc
    13981 atagtagtaa ttcggcatat aattaccata ctcgttgact gctccacgga ggataacatg
    14041 ggccaaagga ttacctgatg tctcaacttc ctgcccatga taaaggaagg tttgcttgtt
    14101 ttgagcagca tagatggcgt taaacataac acccaaattt cctgaggttg gatttttcat
    14161 ccctactggt gcatcaatcc cagaagccac aaagcggtgc tcttggtctt ccacagaacg
    14221 agctccaacg gcatggtagc tgaccaagtc atccaccaag atcagatttg acggataaag
    14281 catctcatct gccgttgtca aaccagtctc tgtaatcacg cggtagtgca actggcgcac
    14341 agcctgcaag ccgttaatca ggcttggagc cttagaagta tctggctggt gaaccaatcc
    14401 tttatagccg tctccattgg tacgaggctt agcagtatac acgcgcatga ccatgaaaat
    14461 cttgtccgct accttctttt gcaaggcgga taaacggcga gcatattcca agaccgcctc
    14521 ttcattatca gaagagcaag gaccaatcac caagagaata cggtcatctt cccctgaaat
    14581 aatatctgcc aattccctgt cacggctttc cttgagtctc aaggcttccg cagacaattg
    14641 ggtttcagcc ttgatgactt ccatatcgat ttcttgacct ttttcaataa atgccatctt
    14701 attctcctaa cgttttgtaa atttctctga caagagcttc tgtgttatcc caacccaggc
    14761 aagggtctgt gatagacttg ccaaatactt ctggctcatt ttgtcgacca tcttccagat
    14821 aagactcaat cataaaacca cgaacgaact gcttaatttt ttcattccaa gcacggttaa
    14881 tcaaggtctg gcggacaatt cggatctgtt caatatactg cttaccagaa ttgtcatgat
    14941 tggtatcaat gatgataaaa ggattttcca agcccatttt ctcatactgg gcaatggtat
    15001 caattaaatt gtcataatag tagttgggaa tattttttcc atactcatta agagcaccac
    15061 gaagaatagc gtgtgaaagc gggttcccag ttgtttctac ttcttttcct aagaaaagga
    15121 aactttgttt gttttgagca gcataaatcc cattaaacat gacattgaga tttccagagg
    15181 ttggattttt aaaaccagta gaaaatcctg ccccacttgc cacaaagcgg tgttgctggt
    15241 cttcaactga acgggcacca actgccatgt aagaaatcaa atcatctaca agcggaaggt
    15301 tttcaggata aagcatttca tcagcagttg tcatccctgt ttctgtgatg acacgatagt
    15361 gaagatggcg aacggctttg attccattga taagactagg cgcttctgtc gcgttaggct
    15421 ggtgaatcaa gcccttatag ccatctccgt tggtacgggg tttggcagta taaacacgca
    15481 taaccataaa gatacgatct gccacttctt cttgtaggac tgccaaacgc ctagcgtatt
    15541 caaggacagc ttcttcgttg tcagatgagc atggcccgat taccaagaga attcgctggt
    15601 cttctccacg tataatggct tctagctctt gatctcgctg tgatttcctc tccaaagcct
    15661 gaccttctaa ttttgacaag gcacgaactt cttctatatt tattttagag ctttttgctg
    15721 taaataccat aactcatctc cttataaagc aaacggatac ccagtaaaaa tttacttttc
    15781 acaagatatc cgcctctaaa ctatctcatt ttattgtctt ttaccgtgac agtttttaaa
    15841 tttcttacca gaaccacatg ggcaaagttc attgcgtcca atctggctca aatccaaatc
    15901 ttctggcata cttgcttggt gagcagcgat attgcgagtc gctgttgtac tgatatgacg
    15961 ttctgcctgt ggtctttctt gttcatgaat ttgtgctttc atcatcaagc gtgtcacatc
    16021 aaactcaatc gaaccaatca tatcattaaa catacggaaa ccttctgcct gatactcaac
    16081 aacagggttg ttctgagcat agccacgaag tccaaccgcg ttacgcaatt gatcaagggc
    16141 atcgatatga tctgtccact tgttatccac cactcgtaga atcaaaactt tttggaattc
    16201 tttaactgct tcttcatcgc gtagttttga aacctgacta tcgtaaacct tcaaggcacg
    16261 ttggaaaagc tcttccttga tggccttatc agacaagcct gacaagtctt ccatcgtaat
    16321 agaatcttca ggaagcaagt tgtacttagc aaagttcaag attgcctcta gtttttcatc
    16381 ttgtttggca cgcgcatgac catcaacgac acgttcaatc gtgcgtttga tcatagcctg
    16441 aatttcaggt gccaagtcac gatctgcagt gatgacatcg taacgttgag catagataat
    16501 ctcacgttgt tcacgcatga catcatcgta ttgaaggact tgtttacggg tatcgtagtt
    16561 atttccttcg acacgtttct gagctgcttc aacctgacgc gtcaacatgc gagactcaat
    16621 ggcctcttca gacatgttca agcgttcaaa gattcccttc aagcgttcag aaccaaaacg
    16681 tttcatcaaa tcatcttcaa gagataggta gaattgtgac tcacctggat ctccttgacg
    16741 acctgaacgt ccacgaagct ggttatcgat acgacgactt tcatgacgtt ctgtaccaat
    16801 aacacaaagt cctccaagtt cacgaacacc ttcaccaagc ttgatgtcgg taccacgacc
    16861 cgccatgttg gttgcgatgg taacggcacc acgttgacca gcattcatga tgatttgggc
    16921 ttctctatag tggtttttgg cattcaagac ttcgtgagga acaccagctg cgaccaattt
    16981 cttagaaatg tagtcactag tttcaaccgc tactgtacca accaagacag gttgaccctt
    17041 ttggtaacga gccttaacgt cttcgacaac cgctttaaac ttagattcaa tacttgcata
    17101 aagaaggtct gagtggtcaa tacgttgaac aggacggttt gttgggattg gaataacacg
    17161 aatgttgtag atttcacgga attcttcttc ctcagtctta cctgtacccg tcataccaga
    17221 caatttcttg tacatacgga agaggttttg gtacgtgatt gaggcagatg tcttggtttc
    17281 atcctggatt ggcacacctt ctttggcttc aatagcttgg tgcaatccat cagaataacg
    17341 acgaccttcc atggtacgac ctgtaaattg gtcgacaatc aagatttctt gctcttcgct
    17401 caccacatag tcaatatcga gaagcatgat gtagttggca cgaagggcgt tatcgataaa
    17461 gtgagtcaaa gccacgtttt caatgtcata gaggttttca agtttgaagt agctttcagc
    17521 cctgtcaatc cctgaatcag acaaaccaat agtcttagac tgcacatcga tgatgtagtc
    17581 atctttgttc aaagatttta catagtggtc tgccatgtga tacaactgac tggtttcaac
    17641 cgcattggca cctgatacaa tcaaaggtgt acgagcctcg tcaatcaaga tagagtcaac
    17701 ctcatcgacc aaggcatagt taagcggacg ttgtaccatg ttttcagcgc gaacgaccat
    17761 gttgtcacga aggtagtcaa atccgatttc tgagttagtt gagtaagtaa tatcacactc
    17821 ataggcttct tttttctcca ttggagattt ggtagccaag ttaatcccta ctgacaaacc
    17881 aagccaagag tacaattcac ccatctcagt cgcgtcacgt tctgacaggt attcattaac
    17941 cgtaactacg tgaacccctt tacctgaaag ggcattgagg tataccggca tggtcgcagt
    18001 caaggttttc ccttcccctg tacgcatctc tggcacgtca ccatggtgaa gaacaatccc
    18061 ccccatgacc tgaaccttat aagggaagag acctaggaca cgtttggcac cttcacggac
    18121 aaccgcaaat gcttcgtaaa gcaatgaatc cagtgattct ccattttgat aacgttcctt
    18181 aaattcaact gtttttgctt ttagttggtc gtcagtcaaa gcagccattt ggtcttcgta
    18241 tttgaaaacc ttgtcagcca tcttttccag acgacggatt tctcctttat cattttcgat
    18301 aattgttttt aaaatattag ccatgttttt ccttacttta aattccgaat attttagaat
    18361 gttcctttaa ttttagcaca attactgatt attttcaagg aagaatcccc attttgaaaa
    18421 ggaaaaagag gttagttttc aagctaacct ctccgacttt tatgactgtt taattgccaa
    18481 aaatcggcaa aatggcaaat gtgataaata agttaatcca aagagaaaga cagcaaatca
    18541 gtccaaaaac aaagagactg actttcttgg acagcaaggc catgagaatg gacagaattc
    18601 caaaaactag caagactttc tgtatgatga agatgtcaat ccttaccccc agaatcgctc
    18661 tatcccaagg gaaaaagaag aaagtcagcc agatcagcag aactaaacca atataaacct
    18721 tggaatagcg tgtaataaat gattttagat gtgccataag ccatctccta ggattgtata
    18781 tcctttacat attgtatatg tccattttcg acaactaata catctgtaca aaggtctgaa
    18841 atatcttccg atatgtgcga cgtcaggata accagaccat tttctttttt caggtaagat
    18901 aaaatgacct gtttggttaa cctcacactc ttctcatcca aagcattcat aggttcatcg
    18961 agaaagagta tagaaggaga ggaaataaag gcttgaatca aggccatttt ttgctttgtt
    19021 cctaaggata aatgacggta ttcaacgtct tcaaattcct gtaaatcata gtattgaatc
    19081 caataggcaa ttcttttttc cgtaacttta gatgaaaaat accttaacag ttccaaattt
    19141 tctctcaggg ataaatgaga taaaaactcg actttttcaa ttaaaattcc tgcatcctga
    19201 atataatgat tttttatccc gtagactttc ccgtcttgaa gaacttttcc tttgtcaagc
    19261 ttaatataac cagcaagtat ctttaaaaga accgtcttgc cagatccatt atcaccttta
    19321 agtccataaa tttttcctga ttgaaacacc aaattcaact gatttaaaat aggtcttttc
    19381 ccataaattt tctgtccatt tataatttca agtctcatcg tttatccttt cttaaatttc
    19441 tcttccaagc gactaacaat caacataact aataaactta aaagtactaa atacactgtt
    19501 acaatatgat ccatcatcca ttcttgtccc acaaatgcta aaaaatagag aaaaaaggaa
    19561 aaaccagcgc ccgcactaat cagtgctatc agataagaca gtagtaagta caacatcatt
    19621 aactgagcaa gtaaaaagaa aagtgcgact gttttgaaat gaattcctat aggaagtaaa
    19681 ccaagaaacc agacaaacaa atcttgagta aaaaatttag aaatgacaac caatcgtttc
    19741 cttgtataat ctaaaaagga gcttgattga tagcgaatca agtgatggta atgatctgcc
    19801 aaatcacttt caagtaaaat gacagagagc catcctacca tgaaaagcga aaggtttaac
    19861 aagagtttgg ggatttctaa attcgcttca gaatagtcat tataggaaaa gattgaaatc
    19921 aattctctct tgaaaaagat aacagcatcc tgcttttgaa ccgctgttga caatagatag
    19981 tttatcaaaa tcatcatcag aactatacga agtagtaaaa caatctttct ctttagcaaa
    20041 atattgttaa aattcttaaa cattatcttc atatttttca agaaccatat aagggacaat
    20101 ataaaggata taaggagtaa agagtttcat caaacttaca tccccatagc tagcttgcat
    20161 caaactcgtc ataggaacca tatagtaagg caaggcacta tagagtaaca tagaaccaag
    20221 ccaaagaaac atcaaatagg cgattgccga acgagtcaca tttcctaaat aatcaactat
    20281 tttaaaaaaa tagactgcat tgatgaaaat accgattagt aggacacaag taaagaacaa
    20341 atagcttgtt atctctccat ctaggagcct ttgtaaacta ctcccgtcag aaaatagaga
    20401 attccatcca agaggagaaa aagtcccaaa gaaatgagtt aaaattgcaa ttatcagcac
    20461 agtcactaaa tatattaaac aagggatact tgcaacttgc aaagtcaact ttctttttag
    20521 cccttgatag ctcacttctc ttccaatact caatcgtaaa actttatttt tcagctcaat
    20581 atattgaaaa cctagcaaaa caatggtgat tggaataata aatgattgat aaaaacctag
    20641 attgaactgg agaatacgaa aatctaatgc tgattttaat aagtcatttt taattgcttg
    20701 tccatcgaat ttagctagat cgggcgcatg aatatcaaaa aagaaataag tcatcaaaac
    20761 atcacgataa accaaagtaa gaaaaagcaa agtaagcaag acataaacaa atttatgcct
    20821 tgcaaaagtt aagagaggaa tcttcataag ccacctccta caaatagaaa gtaatataat
    20881 actcaatgaa aatcaaagag caaactagga aactagccgc aagttgctca aagcactgct
    20941 ttgaggttgt agataagact gacgaagtca gttacatata taatccaagg cgacgttgac
    21001 gtggtttgaa gagattttcg aagagtataa atcaatgcct tccgccttta gacttcccta
    21061 gttcccgtct caagtcaagc atttttttga aacagatata gtctaaccag tcactagcaa
    21121 aagcgataag tagtaataat agccaaatac cccataactt gatatctgtc aaatttctca
    21181 agacgatatt gaaaaacaga actgaaaaaa ctgtctaagc aaggctaaaa agagcataga
    21241 gggtgatgta aatccagtaa aaatagtaaa aaattgggaa aaatttactt tctctattat
    21301 ccttgtcaat ccagctgaaa aagtaaaaac agggtgataa gattatcatt ttaaacaagt
    21361 gttccatcac aagcctcctt ttttaaattg ttttctttag tttcgttcta ttaaatgtta
    21421 ttaccaatat aaaccttgga atagcgtgta ataaatgatt ttagaggtac cataagccac
    21481 ctcctacaaa tagaaaccga tataaatcaa tgccttccac ccttagactt ccctagttcc
    21541 tgtctcaagc gaaacatttc tttgaaacag gaataagtta accaattcat accaatagct
    21601 agcagaataa aaagaaacca aatgccccat aacttgatat ctgtcacatt tctcaagacg
    21661 gtattgaaaa acagaactga aacaactgtc caagcaaggc taaaaagaga atagaagggg
    21721 atgtaaaacc agtaaaaata ataaaaaatt ggaaaaaact tactatttct gttggccttc
    21781 tcaatccagt tatcaaaata aaagtacggt gctaaaagta agaatttaaa caaatgttcc
    21841 atcaccgaca tcaccctcct tcttttgata gcgttttcta ttattttatt atatcaaaaa
    21901 aatccggaac tgtcattcca gattctactt ttttatttgc gttttcttgc gatgagatga
    21961 atcggtgttc cctcaaaaac aaaggccttg cggatttgat tttccaagaa acgcaggtaa
    22021 gaaaagtgca tgagttcttc ttcattgaca aagatgacaa aggttggtgg tttggttgcc
    22081 acttgggtcg catagaaaat cttgagacgt tttcctttgt ctgtcggtgt tgggttgatg
    22141 gcaatggcat ccatgatgac atcgttcaag acagctgatg gaatacgtgt attttgactt
    22201 tcgctgattt gcttaatcat ctcaggaagt ttgtggagac gttgcttggt taaagctgat
    22261 acaaagataa tcggtgcgta aggcaggtat tggaactgct catggatatc ttcttcccag
    22321 tttttcatag tgtggttatc tttttcaagc gtatcccact tgttgaccac gataatcatc
    22381 cctttaccag cttcatgggc aaatcctgcg atacgcttgt cgtactcacg aatgccttct
    22441 tccgcattga tgaccatcaa gaccacatct gaacggtcaa tagcacgcat ggcacgcata
    22501 acagagtatt tctcagtatt ttcataaacc ttaccagact tacgcatacc agccgtatca
    22561 atcatggtaa actcttgacc atctgtatct gtaaagtggg tatcaatggc atcacgagtt
    22621 gttccagcaa caggactagc aataacacgg tcttctccca agatagcatt gatcaagctt
    22681 gattttccaa cgttaggacg accaatcaag ctaaacttaa tgacatctgg attttcttct
    22741 tcatattcat ttggaaggtt ttccacaatc gcatctagta catcccctgt accgatacca
    22801 tggacagatg agataggcag tggttcaccc aaaccgaggg catagaaatc atagatatca
    22861 tttcgcatct cagggttgtc caccttgtta actgcgagga taactggttt gtgggtctta
    22921 taaagcttac gggctacgta ttcgtctgca tcggtaattc cttccttacc ggacacgaca
    22981 aagacgataa catctgcttc ttccatggca atttctgcct ggtgcttgat ttgttccatg
    23041 aaaggagcat cgacatcatc aattcctcct gtatcaatca tgctaaaaga acgattgagc
    23101 cactcacccg ttgcataaat acggtcacgt gtcactcctt cgacatcttc tacaatggag
    23161 attcgctcac cagcgatccg attaaatagg gttgatttcc caacattggg acgtcctaca
    23221 atggcaatag ttggtagggc cataatttct cactttctac aataatttct tctgttcaag
    23281 attttttcta gttgagcttg gttcagcttg accaaactgt tctgctaggc gctgactcca
    23341 gcttgtggtc gcacgcgccc cagcatagtc agcctgaaca cggtcataag cttggattgc
    23401 ctcagttgac tgttcttggt attcttcctc aaagacaaca ttctctagtg gcagtctcgg
    23461 tttcatatca tgatgttgat ttggcacacc cagtgccatc ccaaagacag aataggtgta
    23521 gtcaggtagg ttaaagagct ctgccacttc ttcagacttg tatcgaacca aaccgataat
    23581 cacaccacca tagcccaagc tttcagctgc caacaaggcg ttttgtccag caagagctgc
    23641 atcgaccgaa ctaatcaaga gaccttccac accttggggt tggaaggtgt cggtatgaag
    23701 tcgggctccc ttttctgctc ggttcaaatc tccgacaaag agaaggaaaa cagcagactg
    23761 gcgaatggct tcttgaggta ccaattcata caaggcatct ttcttctctt gacttcgtac
    23821 cacaatcaca gagtaggatt ggaaattctt ccaagatgat gccatctggg ctgctgtcaa
    23881 aatctcattt aagtctactt ggggaatttc ttgctcttta aacctgcgca ctgaagtatg
    23941 agccttcatc aatttaatgg tttctgtcat cgacggttta ctccttctaa acgagtctcc
    24001 tcagccaaat aacggatgcg ttccatgacg cgtctggctt cccaggtttc gtcatttcca
    24061 tgcttccctt tagcgaaatg cagctccaat tcttcaaagt tgaagttgga ggtgaaaaag
    24121 gtcggtaaat tttcctgcat ccgatattgg agaatgacct gcaggatttc atcacgcacc
    24181 caagctgttg attgctcggc accaatatca tctaaaatca ggacttcaga aagcttaatc
    24241 tcatccacca aggtcttgac attaccatca ccgatagcat ttttgacatc aatgacaaag
    24301 ctaggatagt ggagaagagt ggaggaaaca ccacgttttt ctgataaatc atgagctaag
    24361 gcagccacca tgaaactttt acccacacca aagtctccat acaagtaaag accttttcga
    24421 atagctggat attgctccac gaatgctaat aacttttcaa aaactggtaa gcgccccaaa
    24481 tcatccaagt ctacttgagc caaactagct tgcttgagac tggctggcag attgattaac
    24541 ttgagacggt tcttaatagc cgcttctttt tccgctgcga ttagctcagg agtttcttca
    24601 taagaaacat ccgcatagcc atgattcata accaaaatcg gcttgtagcc tttggcaata
    24661 taatccgtat caccacggag aaacttgtcg cgctcggtga tgtactgatt aaacttggag
    24721 atactgcgat tcaattcctc tggggtcaag gattcttgct ggataaaggc cgcaacatca
    24781 gggtccttca tgattttctg gaccaaatct tgataatgaa aacggctagg ttgacgcttg
    24841 agtacgtctc cgacactttc catctaatct cctccttttt ctaatcgagc taatagttct
    24901 tgtttcttac gttctagttc cagacgagtt tcctcgctgg tttcattttt ataatctgga
    24961 ttgctccact tgggtacatt ggacttggca ggactagggg tactgctttt ttgagcctga
    25021 ttcttctgcc cacgctcacg gatgcgcaag actgcctctt ctgccgaatg tatcttttga
    25081 taggcatagt cattggctac cttcatggca tatttctcat tgatatttgc cgaatccacc
    25141 ttattaaagg tcaataaaag aatgatattg atgacttcgt ccagcaagcc caagccagcc
    25201 atctgttgca agagttctct ttctgtttgg gtaatggttc ccttgcgtgt ttgcttgatt
    25261 tctgccaaga actgcagggc agttttactt ttggcttctt tgataatggt tgtttcctta
    25321 agactaaagt cagaggaaat tggtttttga gcaatttttt cacgcatgcg tttggttgaa
    25381 ataacctgag aaacagctgt tgacttggcc aattgatagg tttcaaacca agtccatttc
    25441 ttctcctcgg caatagcaaa gaggtttaag acatcggact gctcatccgc aaaacgaagt
    25501 ccatctcgag ccatcagctg gcgaaaatgt tccaagtcaa aatcattggc cactttcttc
    25561 ttgagaccaa ggtcttcttg actgcctagt tctgccaatt ctggaaagac ttgattgagt
    25621 gagacaggta tttcttcacc atcagcactt tcaactttca aatcctccac agctacatcg
    25681 ccaatctttt tctctaagag tctgcgataa acaggatgcc tcaagaagtc ttgactagat
    25741 agaggagcat ggagggctag ctgataaaca tccccctttt gatagagggt caagagatta
    25801 aaagcagata agattttcaa tgattttatc agtctatcca tcccaaagtt gagatgattg
    25861 aggatacttg aaaaaagata ttccttccta ccattatccc aaaaactgat tgtataaaga
    25921 taaaggctca gtgcctcctg accgataatc gggaggtagc actgtaccag agatgaggta
    25981 tcttgcgaca cccgattatt ctttagataa gaaaaacggt caattggctt catttatctt
    26041 tcctttttct ttttagagga ctgggtgatt tgttggagca agctctctaa ctcactgaca
    26101 tccttaaaac tacgatagac actagcaaaa cgtacatagg taatctcgtc caattcagcc
    26161 aactcctcca tgacgagtga accaatgtcc tcactttgaa tttcattttc atttcgacca
    26221 cggagtttct gttcgatacg attgactacc atgttgattt catcacttga cacaggacgt
    26281 ttctgggctg agcggataat cccattaaag attttatctc tggagaattg ttcccgtgtg
    26341 ccatcttttt taacaaccac taaggttctt tcttctactc gttcgtaagt tgtaaaacgg
    26401 tgttggcatt cgtcgcactc acgtcttcta cgaatggtgt tcccttcttc tgcttggcga
    26461 ctatcgataa cacttgactt ggtagcccca cattttggac aacgcatcct ttccctcctt
    26521 atcgttttct tttcattata ccatttttta agcgattccc aaaacaattc ttctttttgc
    26581 ttgacaagtt ttttgttttg ttgtattatt taattaagac aaaagaataa gagaaaggag
    26641 actaagatgt cctggacatt tgacaacaaa aaacccatct atttacagat tatggagaaa
    26701 atcaaacttc agattgtttc ccatacactg gaacccaatc aacaacttcc aaccgtgagg
    26761 gagctagcta gcgaggctag tgtcaatccc aataccatcc aaagagcctt atcagacctt
    26821 gaacgagaag gatttgtcta cagcaagcga acaactggac gatttgtgac taaggataag
    26881 gagctaatcg ctcagtcacg caaacaatta tcagaagaag aattggaaca cttcgtttcc
    26941 tccatgaccc attttggcta tgaaaaagaa gaactaccag gcgtagtcag tgattatatt
    27001 aaaggagttt aagcctatgt cattactagc atttgaaaat gtatccaaat catatggagc
    27061 aacaccagcc cttgaaaatg tttctcttga cattccagct ggaaaaattg tcggccttct
    27121 tgggccaaac ggctcaggaa aaacaaccct gattaaacta attaatggcc tcttacaacc
    27181 agatcaagga cgtgtcctca tcaacgacat ggacccaagc ccagcaacca aggccgttgt
    27241 agcttatttg cctgatacga cctatctcaa tgagcaaatg aaggtcaaag aagccctaac
    27301 ctacttcaag accttctata aagatttcaa tcttgaacgc gctcatcatc tacttgcaga
    27361 cctgggcatt gatgaaaata gtcgtctcaa gaaactatca aaaggaaaca aagaaaaggt
    27421 tcaactgatt ttggttatga gccgtgatgc tcgtctctat gttttggatg aacccattgg
    27481 tggggtggat ccagcagccc gtgcttatat cctcaatacc attatcaaca actactcacc
    27541 aacttctacc gttttgattt ctacccactt gatttctgat atcgagccaa tcttggatga
    27601 aattgtcttc ctaaaagacg gaaaagtcgt ccgtcaagga aatgtagatg atattcgcta
    27661 cgagtcaggt gaatccattg accaactctt ccgtcaggaa tttaaggcct aagcaaagga
    27721 gattatttat gttttggaat ttagttcact acgaatttaa aaatgttaac aagtggtatt
    27781 tagccctcta cgcagccgtg ctagtccttt ctgccctcat cggaatacag acacaaggct
    27841 ttaaaaatct accttaccaa gaaagtcagg ctactatgct actttttcta gctacagtct
    27901 ttggtggctt gatgcttaca cttgcgattt caaccatttt cttgattatt aaacgcttca
    27961 aaggtagtgt ctacgaccga caaggctatc tgactttgac cttgccagtt tctgaacacc
    28021 atatcatcac agccaaacta atcggtgcct ttatctggtc attgattagc accgctgtat
    28081 tggctctaag tgctgttatt attctggctt taacagctcc agaatggatt cctctttctt
    28141 atgtgattac atttgtagaa acacatctcc ctcagatctt tcttacaggt atatccttcc
    28201 tactaaatac catttcagga atcctatgca tctacctggc tatttccatt ggacagcttt
    28261 tcaatgaata ccgtacagca ctcgctgttg cagcctacat tggtatccaa atcgtcattg
    28321 gatttattga acttttcttc aatcttagtt ctaatttcta tgtcaattca ctggtaggac
    28381 tcaatgacca tttctatatg ggagcaggta tagccattgt taaagaactc atattcatag
    28441 ctatctttta tctcggaacc tactacatct tgagaaataa ggttaatttg ctttaaataa
    28501 tttttaccta gatatgtaac atactcatag aacaaaagag accaggcaaa aagtctttaa
    28561 aattagaaaa cgcatagtat caggtgttaa aaatccttga tattatgcgt tttttgtgag
    28621 ctgacttatt tcctttcact atatcgcaaa atgaaataag aacggaacga tgggattttg
    28681 gaattcaaat caatttataa gaatgtttta gaagtaatat tatcctattc cagattcagt
    28741 tcactataca attgagtttt caagcaacct gtttacataa tgtgtacata attaggttcg
    28801 tgattccacc cttttcacct ttaaaaacct cgctttcgca aggctcttct atttataaga
    28861 taaggcacgt ttaaaggttt tccaaatccc taaatcatcc gtttgaagaa cgagactagc
    28921 atacatgcgt ccgataaatc ctgttgctac caccgcaaaa atcactgtaa tagcaagtga
    28981 aatccatgct tctgctcccc ccgcatagcc attaatcgtt cgaaacggca taaagaaggt
    29041 cgaaataaag ggaatataag aaccaatctt caagaggaga ttgtcaccag ctgcacctag
    29101 agctgtcact ccaaaaaaac cacccataat caaaatcatc aaaggcgaca aggctttccc
    29161 tgagtcctca ggacgagaag ccatagatcc taggaaggct gccaagacta cgtacatgaa
    29221 aagactgatc aaaataaaga gcagggtatt cagtgagata gcatctccca agtgaaccaa
    29281 aataccagac tgagccaaga atggcaaatc tttaaagagc aaaacggcag ccagaccacc
    29341 tacaacatag atcccaatat gcgttaaaat cactagaaac agagccatca tccgcgcata
    29401 gaaatagtga cttgccctta tgctagaaaa aacgacttcc ataattttgg tgcctttttc
    29461 actggcaact tcctgagctg ttacacccgc ataggtaatc agaatcatat aaagaaagaa
    29521 tcctaaggca cctgctgcaa ttgtttgaat aaacttttta ttttccttgg cttcatcaat
    29581 cttttctgtg aattgaattg tctgcgctaa gcgtttttcc tgctcttgag acaaggaagc
    29641 agttgaacga ttaagctgat tttgcagttc attgagtgta cctgtaacct caaatttaat
    29701 tccattttca agcaatgttt cgccatgata aactgccttt agaacactat cttcttgatc
    29761 aatggtcaaa taacctttta atttttcttc tttaattgct tctttggcac ttgcttcgtc
    29821 tttatagtcg aagttaacac catttacatt cttcagtcct tctgctacag atggcactgt
    29881 tgtcactact gccactttat tatttttagc catagaagaa ccttggatat gcccaattcc
    29941 tacagagatt cctaaaaaga ggaacggcga aatcaccata aagaagaaac tccatgactt
    30001 gacatgtcga agataggttt ccttgattac aacccacata tttctcatac ttccactcct
    30061 gattctagtt taaagatttc atcgatagtt ggcgcttgtt ggtcaaatgt tgcgatatat
    30121 tgaccttgag tcaagattgg gaagagttcc cttccagcgc tctcatcctc caaaatcaat
    30181 ttccaactgc cttgtttggt caagctcacc tgtttgacat gaggaagatt ttccagttct
    30241 tccttgcttc gttcactgga aacaaagaga cgcgttttcc cgtattgatt gcggacatcc
    30301 tgaactggtc cgtgcaagac cacacggcca tctcggatca tcagaatatc gtcacaaagt
    30361 tcctcaacat tggtcatgac atggtcagaa aagataatgg ttgctccgcg ctctttttcc
    30421 tgaaaaatga cttgtttgag caattctgta ttaactgggt ccaatccact aaaaggctca
    30481 tccaagataa tcaggtctgg ttcatgaatc agagtaataa tgagctgaat cttctgctga
    30541 tttccttttg acagactctt gattttatct gtcagctttc ctttcacttc caacctcttc
    30601 atccattgag ggagtttttc tttgacttct ttggcatcca tgccttttag agtcgccaag
    30661 tagcgaactt gttcaagaac tgtcaattta ggcatgagac tgcgttcttc aggcagataa
    30721 ccaatccgag cataggtctc ctgacgaata tcctgaccat ccagaccgat ttctccctga
    30781 tattctagga attttaaaat actatggaaa atcgttgttt ttccagcacc attttttccg
    30841 actagtccca aaatacgacc tggtcgcgct tgaaagtcaa taccaaacaa aacttgcttg
    30901 gatccaaaac ttttctctag acttcttact tctagcatct ttcacctccg aaatttcttg
    30961 cactcattat actccttttt gataaccttt acaacgtttt gtgtccattt ttagaagact
    31021 attgctgtgt aaaatatggc ctggagcact tttatactca atgaaaatca aagagcaaac
    31081 taggaagcta gccgtagact gctcaaagta cagctttgag gttgcagata aaactgacga
    31141 agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gtaactatat
    31201 ctacggcaag gcgaagctga cgtggtttga agagattttc gaagagtatt agtgataaat
    31261 ccattataca gcagcaaact taatttatac cttccgctcc tcaactgtct atttttaatc
    31321 ctgaattgtt atttgagtaa ctcctttttc ctcgtaaagt tttcttcctc taaaacttct
    31381 ggaaaaaggc taatagtttc agacaacatt tttataagaa acaagttcat ctgtcatttc
    31441 aagaaggagt aatcctttat ctactaatgg acggaacaga attcaaccgc ttgtccgata
    31501 tgttttctaa ggattatata gtaaaatgaa ataagaacag gacaaattga tcaggacagt
    31561 caaattgatt tctaacaatg ttttagaagt agatgtatac tattctagtt tcaatctgct
    31621 atatctatta tgcacacccc tataggatct aatgaaaatc acaacaggct cattcataga
    31681 tggttacctc aggaaactaa gaaaacgact acaaaggaag tcgcattcat cgaaaagtgg
    31741 attaacaact atcctaaaaa atgcttgaac tacaagtccc ccagagaaga cttctggatg
    31801 actaacttga acttgaaatt tagcaataat taattcacca tctaactata tttagtaatt
    31861 atttcagaac tgattaatat taaaattaac taacaattca aaggattcat actagccata
    31921 aattacgtcc atcagagaga gactcttact acttttagat tttagtcttt ctagcttcag
    31981 aatacatcta aactttaggg aaaatgacta ttcgaaagcg cgaatgcctc aaaattatct
    32041 cagataagct attcgaaact tagaatgctt ttaaatttat ggaattgcga ttattcaaaa
    32101 cctagaatgc atataacctt tagttgacag acctattcta agtctcgaag ggctatttac
    32161 tttctattcc ttatcaaaaa agactcattc cccctttctc ctccaaaata tggtatagta
    32221 gaaatatact atctatgagg agtttacatg tcacaggata aacaaatgaa agctgtttct
    32281 ccccttttgc agcgagttat caatatctca tcgattgtcg gtggggttgg aagtttgatt
    32341 ttctgtattt gggcttatca ggctgggatt ttacaatcca aggaaaccct ctctgccttt
    32401 atccagcagg caggcatctg gggtccacct ctctttatct ttttacagat tttacagact
    32461 gtcgtcccta tcattccagg ggccttgacc tcggtggctg gggtctttat ctacgggcac
    32521 atcatcggga ctatctacaa ctatatcggc atcgtgattg gctgtgccat tatcttttat
    32581 ctagtgcgcc tatacggagc tgcctttgtc cagtctgtcg tcagcaagcg cacctacgac
    32641 aagtacatcg gctggctaga taagggcaat cgttttgacc gcttctttat ttttatgatg
    32701 atttggccca ttagcccagc tgactttctc tgtatgctgg ctgccctgac caagatgagt
    32761 ttcaagcgct acatgaccat catcattctg accaaaccct ttaccctcgt ggtttatacc
    32821 tacggtctga cctatattat tgactttttc tggcaaatga tttgacacgt aaaaaatccg
    32881 tttggtttct caagcggatt ttgtgcttta ttttgaaact tcttttgcaa gaacaaagtt
    32941 cccaagtgtg gcagaaccat ttcctgcgac tgctggcgtc acgatatagt cacgcacatc
    33001 tggtactggt aggtaaccat taagaagaga tgtaaatttc tcacggacac ggtccagcat
    33061 atgttgttga gccatgaccc ctccaccaaa gacaatcacg tctgggcgga aagtcactgt
    33121 cgcattaacc gcagcttgag cgatatagta ggcttgaaca tcccaaacag ggttgttgag
    33181 ttcaatattt tccccacgta cacctgtacg agcttccaaa cttggaccag ctgcatagcc
    33241 ttccagacat cccttatgga aaggacaaac acccttaaac tctttttcaa tatccattgg
    33301 gtgtctagca acataataat gacccatttc agggtgaccc acaccaccga taaactcacc
    33361 acgttggatg acgcctgcac cgatacctgt accgattgtg tagtaagcca agttttcgat
    33421 acgaccacca gcattgttac gggcaaccac ttcaccgtaa gcagagctgt ttacgtctgt
    33481 tgtgaagtac attggcacgt tgagggcgcg acgaagggca ccaagcaagt ccacatttgc
    33541 ccagtttggt tttggagtcg tcgtgataaa gccataagtt tttgagtttt tgtcaatatc
    33601 aatcggccca aatgaaccaa ctgcaagacc agcaaggtta tcgaattttg agaagaactc
    33661 aatggtttta tcgattgttt cgattggagt tgttgttgga aattgtgttt tttctacaac
    33721 gttaaagttt tcatcaccga cagcacagac aaactttgta ccgcccgctt ccaagcttcc
    33781 atataatttt gtcatgataa acctcttgtt tttattttct ttattatagc atacttcgaa
    33841 agtctaaatg tctctatttt ttagattttc ctctgtaaat cttactatct aataaaaacg
    33901 aacaaacatg tcatttgttc gttttcacat tagagaggat tgattagatt ttcacttcga
    33961 tcacagcatc ccccttcgca actgaacctg ttgcgactgg agctactgaa gcgtagtcag
    34021 ctgtatttgt aacgataacc attgttgtat catcaagtcc agctgcagcg attttgtttg
    34081 agtcaaatgt tccaagaaca tcgccagctt tcaccttatt accttgagca acttttgctt
    34141 caaaaccgtc accgttcata gatacagtgt caataccaac gtgaatcaaa acttcagcac
    34201 catttcttgt tttcaaacca aaagcgtgcc ctgttggaaa gacaattgaa acttcagcat
    34261 cagctggtgc atagaccacg ccttggcttg gtttcacagc gataccttgt cccatagctc
    34321 cacttgagaa gactgggtca ttgacatcag caagagcgac aacatcaccg acgataggag
    34381 ttacaagtgt ttcattttga agagtatcag tctcttccac tactggtgct tctactgtag
    34441 gttctgtaac tgtttctgcg gttgctgtgg cagcttcatc agcaaagaca ctagctgctt
    34501 ttgttttccc gtagaaataa gtgaaagcaa aggcggcaac aaaggacata atttccgcaa
    34561 ttatatacat aggaattgaa ccagccttaa tagaaaggaa tccaataaat ccagccgctc
    34621 ccaatgaaac tgcaataacg tgagttaaac ctgctacaaa ggcaccaatt gctgaaccag
    34681 caagggcgca gaagaatggg aatttgtatt tcaagtttac cccaaagaga gcaggttctg
    34741 taataccaag gaaggcagaa acagcagccg aactggacaa tccttttgtt ttagcatttt
    34801 ttgtcaagaa gtagactgca agagtagccg caccttgtgc tacgtttgcc attgaagcaa
    34861 caacaaagat gtagtctcca aatccagtac cgttattatt gtatgcagac aacaattgtg
    34921 tttcgattgc tgggaatgat tggtgaagac ccgtcataac gattaatgag taagttccac
    34981 caaatagccc cataccaaag gcacctgttg tgttgtacaa ccatacaatc gcatttgtaa
    35041 tcgcatcaga cacaaccaac ataacaggac cgataactgt aaaggtaagg aatcctgtaa
    35101 tcatcactga taaaagcggt gtgaaagtga agtcaactgc agatggcaat ttcttgtgga
    35161 agaatttttc taaattagct aacaaccaga ctgcaacaag gactggaata acctgataag
    35221 catagtttgt ttgtgtaaca tggaaaccta agatgtccca gaaggcttct ttaccaccca
    35281 aatctggagt ggtcataatc ataccgattg ccgcaccaag gaattggttt gctccaaagc
    35341 gcttggctgc tgaaatacca accaaaacag ggaggaacat aaatggagca gcagacatca
    35401 attgaatcat agctgagaag cctttgatag caggatacat atcttcaatt gattgaggtc
    35461 caaacaaatc tggtgatgtc aagaagttcc gtaaagccat caagagacca cctgcaacta
    35521 aggcagggat aataggaaca aaaatgtctg acaaaagttt aatcaagtcc atcaatggat
    35581 tgaacttttt gtctttatta gcaatctctt tcaaatcatc tgtcgaaact tctttcaaac
    35641 cagttttctt aataatttcc gcatatacga agttaacatc accaggacca atgataattt
    35701 gatattgtcc gttagtgcta aaagtcccct tgacatccgc attattatcc agagctgctt
    35761 gattcacttt tgcttcgtct ttcaatacca agcgaagacg tgtcgcacag tgagctgcag
    35821 ctacaagatt atccttaccg acagcctcaa tgacctcggc agcaacttta ctataatcca
    35881 tagcaaaaat ctccttatat aacattttgt tcttgtttga aagcgatttt attcgccctt
    35941 acgactatta ttttatcatg ttttaaaaat atgtcaagcg ttttgcagaa aaaatattct
    36001 atctacttag tgggcaagct ttagattgat tgtttttgac tgtttcatca ggaatttctt
    36061 gaaaaataag tttgaaacct tggttaaaaa gtctttcatt tcattatctt tcacattttc
    36121 gtaaaaattt gattgatttc ctgtatttat tttatgataa tcgtttgaca gttttttctc
    36181 ttttttaata taaaaggctt gcatttttta tcgaaaacag ttactattaa aagtgataag
    36241 atttttggag gaatgaatgg aatggacaac tgagcgtcgt tacagacttt atcaagattg
    36301 gacgcaagaa gaaattcaac atataaagga aaatatggca caatctccat ggcatactca
    36361 ttaccatgtt gagccaaaaa caggacttct caacgaccca aatggctttt cttactttga
    36421 tggcaagtgg atcctctttt accagaattt tccttttggt gcagcccacg gtttaaaatc
    36481 ttgggaacag ctagaaagtg atgatttgat tcactttaaa gaaactggaa tcaaagtttt
    36541 accagatact ccattagata gccacggtgc ctactctggt tctgccatgc aatttggcga
    36601 taacttattc ctattttata caggaaatgt tcgcgataaa aactggatcc gtcacccata
    36661 ccagatcggt gctttgatgg acaaggaggg taagattaca aagattgaca agatcttgat
    36721 tgaccagcca gcagactcta ctgaccactt ccgcgatcca caaattttta actttcaggg
    36781 tcaatattat gccattgtcg gcggacaaga cttggagaaa aaaggtttcg ttcgtctcta
    36841 caaggctgtc aataacgact acacaaactg gcaagcagtt ggcgaccttg actttgctaa
    36901 cgaccgtact gcctacatga tggaatgtcc taatctggtc tttatagagg aacaacctgt
    36961 ccttctctac tgtccacaag gattggataa gaaagttcta gactacgata atatctttcc
    37021 aaatatgtat aagatcgggg cttcctttga ccctaaaaat gccaaaatgg tagatgtgtc
    37081 tcaacttcaa aacatggatt acggtttcga agcctatgca actcaagcct tcaacgctcc
    37141 tgatgggcgt gctctagcag ttagctggct tggtttgcca gatgtttctt acccatctga
    37201 ccgttttgac caccaaggaa ccttctcttt ggtcaaggaa ctcactatca aagacgacaa
    37261 gctctaccag tatccagtcg ctgctattaa ggaccttcgt gcttctgaag aagccttctc
    37321 aaactgttcc caaaccaaga acacttacga acttgaactc aacttggaag ctaatagcca
    37381 gagcgagatt gtcttacttg ctgataaaga aggtaaggga ctttcaatca actttgacct
    37441 tgtaaacggt caagtgacag tggatcgtag ccatgctgga gaacagtatg cccaagaatt
    37501 tgggataact cgttcttgcc ctatcgagaa tcaggctact actgctacaa tcttcatcga
    37561 taactctgtc tttgaaattt tcatcaataa aggagaaaaa gtattttctg gtcgtgtctt
    37621 cccacatgcg gaccaaaatg gtatcctgat caaatctgga aacccaactg gaacttacta
    37681 tgaattagat tatggtcgca aaactaactg atgtcgccaa acttgcaggc gtcagtccta
    37741 ctaccgtttc tcgggttatc aataaaaaag ggtatctatc tgagaaaacc atccaaaaag
    37801 tcaatgaagc catgcgagaa ttgggctata aacccaacaa cctggctcgt agtctgcaag
    37861 gaaaatcagc taagttaatc ggcttgattt tccccaatat ttccaatgtt ttctatgcag
    37921 aattgattga taaattggaa caccaactct tcaaaaatgg ttacaagacc atcatctgca
    37981 acagtgaaca tgattctgag aaggaacgtg aatacatcga aatgttggaa gccaatcagg
    38041 tggacggcat catttctggt agtcacaacc taggaatcga agactacaat cgtgtgacag
    38101 cgccgattat ttcctttgac cgaaacctat cgccagacat ccctgtcgtc tcctctgaca
    38161 actatgctgg tggggttctt gctgcccaaa ccttggtcaa gacaggtgcc cagtctatca
    38221 tcatgattac agggaatgac aattccaatt cgccaaccgg actgcgccac gctggttttg
    38281 catccgtact cccaaaagct cctattatca atgtttccag tgacttttct cccgtcagaa
    38341 aagaaatgga aatcaagaat atcttgaccc gggaaaaacc agatgccatt tttgcttcgg
    38401 atgatttgac agctattctg gtcattaaaa tcgctcaaga attgggcatt tctgtcccaa
    38461 aagagctcaa ggtcatcggc tatgatggga cctactttat cgaaaattac taccctcaat
    38521 tggctactat caagcaacct ttggaagaga ttgcttgtct cactattgat cttctcttgc
    38581 aaaagattga aggcaaggaa gtcgccacaa ctggttactt cttaccagtt acactattac
    38641 caggaaaaag tatttaaaca caagaaaact cagaccgatt cgtctgagtt ttttatgatc
    38701 ttaaattttc gagatagcgc tgggctgtct ctaggttaaa ggttttatct gcgataagct
    38761 gctcgactag gggagcaact tcagattcac tagccccagc taggagagct agggatttgg
    38821 cctgtagttt catgtggcct tgctggatgc ccgtacttac caaggctttg agggctgcaa
    38881 aattttgggc aagaccgatg gacacgataa tctgggctaa ttctctggca gaaggatttc
    38941 ctagtagatc atgactgaga gctacacgtg ggttgaggcc gatagagcca cccttagtcg
    39001 ctacaggcat gggcagggtc atctcaccga ccaattcttc tctttcaagg tccagcgtcc
    39061 agcaactaag accttgataa cgtccatctc gactggcaaa ggcatgggcc ccagcttcga
    39121 tggcacgcca gtcattacca gtggcaatca aaatcgcatc aataccatta aaaattcctt
    39181 tattatgagt agcagctcgg taaggatcag cctgcgcaaa ctgactagcc aacgcaattt
    39241 tctccgcaat ctctcgtcct tgatcctttt ggctgctcaa gtagcgaaag gcgatgcgac
    39301 agcttgcagt caccagagaa tcggtcgcgt agttggacag gattcccatg agactctgtc
    39361 cctgactgag ttcttctaag actggtttca aggcttccag catggtgttg agcatattgg
    39421 cacccatggc ttcctgggta tcgacatgaa tataaacaac gagaaagtct ggttcacctt
    39481 ttatctgctc gacatgcagg tcacgcgccc cacctccacg tttaacgata gaaggatagg
    39541 cttgattggc aagctccaag agctccgctt tcttgctggc aatcttctct tgcgctagtt
    39601 taggattagc aacttgataa agggatacct gcccaatcat ctggcgctga tggacttgtg
    39661 cagtaaaacc acctacatgc ttgatgattt tgctggcata gctggccgcc gcaaccacag
    39721 agggttcttc tgtcacatag ggaacggtgt attcctgacc gttgacaagt acctccggaa
    39781 ccagcgaata aggcagagaa aaagttccca ccacattctc actcagctgg tctgccacag
    39841 tcacactcat ctgttcatcc tgctccagac tagcttgtct ctcaggacta aggagcgcct
    39901 gagcttttaa cagctcgagg cgctcttggt atgatttttt agaaaatcca ttccaactta
    39961 tcttcattat ttttcaacct tgctataacg gcgttggtgg tcgagaattt caaccaaggc
    40021 aaaatattga ttttcatagc cagcaaactg ggcagagttt gtttcatcca agtctacttc
    40081 ctcaaaaaag accttttcat agtctgcaac ggataggtca gttcgttggt tgagcttgtt
    40141 caagcggtct ttatccaaat aagcttcata tccttcaacc aattcaccac tgaagaactc
    40201 agccacagct ccacttccgt aactataaag ggcgatttta tccccagctt tcaagctatc
    40261 tgtattttcc aagagagaca aaagtccaag gaaaagtgaa cctgtgtaga tattccccac
    40321 cttttgacta tagagaatag aatggtcaaa atggttttgc aagaggtctt ttttctcttg
    40381 aggcaagttc ttatccataa tttttttcaa gccttttagc gctaatttag gataaggcaa
    40441 gtggaagcaa accgccgcaa aatcatctaa ggtaagctgg tagcgttttt ggtattcaag
    40501 ccaagtcgtt ttcaaactat ccaagtattg ttgggtagaa tagacaccat ttacataagg
    40561 agttgtcgag taatttggtc gccagaaatc catgatgtca cgggtctgag ctacattgtc
    40621 attattaaag gccatcatgc gtggattttg tgtaatcaac atagccacac ttccagcacc
    40681 ctgagttggt tctcctggag tttcaattcc atacttggca atatcactgg cgatgaccaa
    40741 gactttcgac tctggagaat tttccacatg caatttggca taatgaaggg cagcagtcgc
    40801 tccatagcag gcttctttaa tctcgaaact acgagcaaag ggctggatgc ccagcaagcc
    40861 atgcacaaag acggccgcag ccttactctg gtcaattcct gactcggtcg ccacaatgac
    40921 catgtcaact tcttgtcttt cttgctcagt taaaatagag tcactagcac tggccgccaa
    40981 ggtcacgatg tcctcagtta ggggcgcaat actcaattcc ttgagtaaga gtcctttact
    41041 taatttttca gggtcaattc ccctcgcttc tgctaagtct tgtaatttca agacatattg
    41101 actggtcgca aaaccaatct tatcaatacc gattgtcata tttacctctg ttttatcatt
    41161 catgtaaaaa atcgttctat actattttat cacaaatggc agtaaaagag agaaaaaaga
    41221 cttgattcac caaatcaagc ctcttattgg tcataatttt aaagaatgat tagttgatat
    41281 agagttcacc gatataagta gctttataag cttcattcac agttatcagc tcctggagga
    41341 tcaaatttcc tgagtaagtc cttcccatct catctacaaa ttcttgataa aactgactgg
    41401 tcggaatttc tctgacatcc ttatcaaatg tcttgtcaag tgttttacta accttctcag
    41461 caatcaattg atgctcttgc catccacttt gaaactctga gcccgaacta gaaaccatga
    41521 ctgggataaa caacaaggtc catagactta cagacaataa ggaaaatagt agacttcctg
    41581 caaaactaga atcctagttc atgattgata atatcagcaa tcaaattcat tcgtaatccg
    41641 aagcgtttac gatgatttcg ataggttgtt gaaatcattt taaacgtttt tactttggca
    41701 aagatgttct caaccttgct tctctccttg gatagcgcat ggttacaggc tttatcttca
    41761 actgttagcg gcttgagttt gctggattta cgtggagttt gtacttgagg atatatcttc
    41821 atgagccctt gataaccact gtcagccaag attttaccag cttgtccgat atttttgcga
    41881 ctcattttga acaacttcat atcatgacaa tagttcacag cgatatccaa agaaacaatt
    41941 ctcccttgac ttgtgacaat cgcttgagcc ttcatagcgt gaaatttctt tttaccagaa
    42001 tcattcgcta attgtttttt tagggcgatt gatttttact tccgtcgcat caatcattac
    42061 cgtgtcctca gaactgagag gagttcttga aatcgtaaca ccactttgaa caagagttac
    42121 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
    42181 ttcttcataa gttcgatatt ctcgcacata tagaaagcgt tgttactata tttatctcat
    42241 ttttcagaaa attcttttat ttctgtaaaa tctacgatac tcgatgtgtt tttatataat
    42301 gatacagtct gagaatcact gttccgctag ctattccaat agagattacc aaagccagca
    42361 tgacaaccaa ggtcgcactt gccagcgctt tattatagtc tcctgtcaca aaaaaggcag
    42421 ttgtccgata agaaaggtag cccggaacca gcggtgccaa aatggccaag ataaagacca
    42481 cagcaggagt cttataaaga atacttaaaa tctggctgac acaagaaccg attatggcgg
    42541 caataaaggt agccacaata acattggtcg gttccttgag caagagataa atcagccaga
    42601 cagccatgcc caaaatccct ccaggtaaga gcatagagcg ttgcacattg agtacgatta
    42661 gaaaagtgat aatggcaaga agacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
    42721 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcaag ggtaatgagc
    42781 agagattcaa acatcttgct cataccagag tttatgtggt tggtcataat atcacgaacc
    42841 gcattggtca aggcaatccc tggtacaaac ggcatgaccg caccagctat aatcaaatct
    42901 gctgttgaag gaaagcctgt gtagcgagcc caaaactggg caatcatccc aaagacaaag
    42961 gctccagcaa aggctgtcac aaagggaatt cggataaact tctccacata gagggaaaag
    43021 gcaaagccaa ataaagtagc cactcctgcc ccaagtgcgt cgtaaatatt tccactaaac
    43081 ataattgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
    43141 ggaaggggtt gggcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa atcaatctgc
    43201 cccccaacca gctgacgaga aatctggttc acatcgcaga ctttttcaat gttataagaa
    43261 gaggaggtca cgcgcttcat gcgcgaaata ttagtatttt caatagagaa aaagatagca
    43321 gcaggcatgg caagaacatt gcaatccaca atcccctgcg aatgcgcgat ccgaatcatg
    43381 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
    43441 atcacatcga tgacggcatt taattctttt gactcttcca tgcttgcctc cttttatcaa
    43501 ctccctctat tctatcacaa atccggactc aaaaaaaatc tttgccacaa aatcatgaca
    43561 aagattgatt actcattttg attatccatc tgattttaag gagtagctga acttgtttta
    43621 ggtttgtaga ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta
    43681 ggactctgtt caacgactgt accttcagca gttccagcgg gagctgtcga cacttctaca
    43741 acttcaatat tggcttcctt aatcccaaca atttgaatca aattattctt agtaaactcc
    43801 aagctggaac caatgtagct cggcatggca acacttgtaa cttttttagc tactgtcaag
    43861 acgatttggg taggtttatt cacatcataa gtcgttccgg cacctggact ttgtttcata
    43921 atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa attatctgga
    43981 acttttttct cttttaattc cgcaataaca tcagaggatt tccgtccaat atagttccct
    44041 aattgaatcg tcgtagcttt tttagctact gtcaagacga tttgagttgc cttgctcaag
    44101 tcataggtcg taccttctgg tagactttgc ttcatgaccg ttccagcctc actctcattc
    44161 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgca
    44221 atgacatcag aggatttccg accgacataa ttactaattt ggaaggattg tttgcctgat
    44281 gagacaacca aattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
    44341 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
    44401 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
    44461 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
    44521 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
    44581 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
    44641 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
    44701 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
    44761 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
    44821 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
    44881 acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
    44941 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatagcata gatatcactc
    45001 tgcacagtcg ccttcgaacc acgcgcctgc tctggggaca agtaatgaac tgagcccaac
    45061 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
    45121 accttggcag tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
    45181 attcctctgg tatgggccaa acgcatggct aggaggattt gtcccatgat acggactgct
    45241 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtctag tccagcaaca
    45301 tactccattg caagatactg ttgaccgtct tcctcaccaa tatctgttat ccgaacgata
    45361 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
    45421 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
    45481 aagtctttgg ctaggtagac atccgccata cctcctcgac caatctgttt gacaatccga
    45541 tagcgtccgg caaaaatctt gccgatttgg atcattctgc atcctcctcg ttcatagaaa
    45601 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
    45661 ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa
    45721 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
    45781 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
    45841 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaac tcattgacca
    45901 aagaatgatc actcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
    45961 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
    46021 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
    46081 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag
    46141 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcgcga tgacctccca
    46201 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
    46261 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
    46321 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
    46381 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
    46441 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
    46501 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
    46561 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
    46621 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
    46681 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
    46741 agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
    46801 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
    46861 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
    46921 cgtcggagca accagctgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
    46981 attatgccct gcaaaatgcc cttgctcctt aacgagacca gtggttgcta aaagggaatt
    47041 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
    47101 ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc
    47161 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
    47221 ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc
    47281 gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg cttcattaac
    47341 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
    47401 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
    47461 cagagtcagt ctacgggcta ccgttccata gaccagctcg gtcactaagg ccttgtctgc
    47521 tgccaaaagt tgacttccct ttagatgctt atttaaggcg atatttgaat atgcttggtt
    47581 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
    47641 caaatcgttc tcctacagtc aatgtacgtc caactccgtt gaggaaggaa gcaatgtcca
    47701 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
    47761 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
    47821 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
    47881 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
    47941 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
    48001 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
    48061 ccaatttttc aaacaaggcg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
    48121 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
    48181 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
    48241 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
    48301 caaaagcagc agtcacaatt ccatctgctc ctagctttat aagttcttcc atctctggac
    48361 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
    48421 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
    48481 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
    48541 gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat tgctgcggct
    48601 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct
    48661 ggttgagggt cagccccagc tcatcttcta aacgatattt aattaaaatc tggtaatgat
    48721 agagattgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
    48781 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
    48841 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagcag agttgtcgtc
    48901 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
    48961 catagtgctg cgaattgtag gactgtatca agacttgacc tgctttttca gcccgacctg
    49021 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
    49081 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
    49141 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
    49201 gcaaggcttg gtgactacct ttctttcgag tcgtatccac atccatcctc agaatgcgag
    49261 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
    49321 gaatactgtg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
    49381 aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
    49441 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cgacgattga
    49501 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
    49561 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
    49621 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
    49681 tgccagcacg cgcccggctt tctaagctcg gcgttgcaga tccaagtacc agagttgctt
    49741 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctgtcct
    49801 gcttataagc cacttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
    49861 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
    49921 attcatcata cttttcacca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
    49981 aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt accagcaaaa
    50041 tagctgtctt gcccttatcc agggtacctt ggataatctg caagtaaacc tcggtcttcc
    50101 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
    50161 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
    50221 cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca gcaccttgat
    50281 ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
    50341 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
    50401 tctcaacacc ttctaattga acatggtcaa cctcatacca agactgggtc ttgaccttct
    50461 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
    50521 cagcttgctt acctaaatcc agagaagaaa aggcaagtga atcttctgaa ccaaacaggc
    50581 gtactcgttc ttcctgactc aagccttcca gaggatatag aatcttgtca tagctagaat
    50641 tcagaaatcc cggaagcatg gccttgagga tggaaatttt gtaggagaag acggacttgc
    50701 gtaactcctc agcaagccag agttgttctt gcgtgagaac gggagaaaaa tccagtacct
    50761 cggcaatatc ttttaaatct tgctccatct cttcttcgtc tgattgagac tccaaaccaa
    50821 gaacaatccc ttgaatcagg cgattgccct taccaaaagg cacatgaacc cgcatcccaa
    50881 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
    50941 tcaagggcac atctacgata atcttagcta gggccatctt ctcacctcct ccttgtcagt
    51001 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
    51061 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
    51121 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
    51181 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
    51241 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
    51301 tgaatatttt gaagtaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
    51361 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
    51421 gtgaccaatg acacgatcca cacaaaagtg ttctgcttca atcacacatt tgacacgttc
    51481 agcagctagg gatacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
    51541 ttcttccttg gccttttcga ttcgttgggc aaccacttct gcactatctg ttccacgacc
    51601 taccaagcgt tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
    51661 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
    51721 tcccttgtcc aaggtttcat tgacataagt cagaggagtt ccatagtagt tgccgacata
    51781 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
    51841 gaagaaatag tcgacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
    51901 agagtattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
    51961 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    52021 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    52081 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    52141 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    52201 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    52261 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    52321 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    52381 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    52441 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    52501 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    52561 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    52621 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    52681 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    52741 cattaagtct ggatgaaggt ttggcgcacc aatctcatag gctgctgcct caccgtattc
    52801 acggatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    52861 gtggatacga ccatccttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    52921 cgggtcaaat cctgacaagg tcaccacttc tggcgtatcg tcgataatca catcaacacc
    52981 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    53041 agtatcgtct ggtagatgaa ccgttgagtt tgttgactcc gctacatatt caccagcgat
    53101 acgttgcata gcttgaacca agatgtcctt ggccatttta tcagaacgtt ccttgacctc
    53161 ttgctcagct tcgcgaatac ggctggcaat ctccttggtc aaattttcct ctgtctgagc
    53221 caagataata tctcgtgctt ctgcctgaga cagggcacca atacgctcta actctgcttc
    53281 ttttcgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    53341 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    53401 acggtcgagg ctagtagctc tctcggtcaa acgactttct atttgtttga gttcttgacg
    53461 ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    53521 caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa ccagtaaatc
    53581 cgcttcacgt tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    53641 caactccgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    53701 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    53761 tcattttatt gttattctga atgacatata ttcttttaca ttctaccata aaaaagtgat
    53821 tttcacaaac ctaaaataga atatgttttg gggaaattag cgtgaatttt aagattacac
    53881 ttcttcggat cccttcaaac ttttgaatac atcatcaata aatatatctg ctaatctctt
    53941 cttgaaagaa tcattattta atagagcacc aaataaatct tgactctgag agtatccttc
    54001 tataagagca ttgtcaatct cttcttcaaa agcaaaaacg aagtcttctc tggagttgac
    54061 acgagcagat tgctttagtc ttggattctt tttcatcaat tcacgaatgg ataccgctcc
    54121 acttagaccg acttggggat caatatccaa atccaactgt tcgttaattt catctaagat
    54181 ttcagataaa cgcttctcct ggtcagtcgt aacacctcca gtacttggct tggtaagtat
    54241 taactctgga tgatattcca attcagaaac tgacctgaag gaacctgttt gcttatgttt
    54301 catatagtcc actacgatct tatctgctat tgtaaaatca tctcctccaa tgcgaacatc
    54361 aatcatcttg acaagacttt gcagataatt ataacgttcg tgtagaactt cattttgata
    54421 agcagttgcc tgaatcaaga aagtatacat tctaagaaaa cctcgaataa cctttcgaat
    54481 agaaagttgt tctttctcat caaaccgtct aactctatca taaccttgat ttaacagaga
    54541 aaccatcttt tgcttttctc tgctgtttct cttttcttgg tataagaatt gattaaactc
    54601 atgaataaca tcactgtcca agataccata ctcatcaatt ttccgatcca aggtcaagac
    54661 atcactaggt gtgactgtat ctgctaaaat agtctcacgg tagtagggag aaaaagctga
    54721 acgaatatcg tcataagtat ttttaaaatc aagaataaag gtcctcttat tgtagcctct
    54781 atagatacga ttcaaacgag acaatgtttg caccgcagca acacttcgca actttttatc
    54841 tacatacata gcaaccagtt tgggttggtc aaaccctgtc tgatacttat ttgccacaat
    54901 cagaatttgg tagtcttccg tatcaaaatg atctttcaaa taatcttcct tgacctgatt
    54961 catttgcgac tcagtatatt cactaccttg ataatcaacc ttgccagaaa aggcaatcag
    55021 ggttccaata ctggtaatgc tgtggtcttt gaagtacttt tgaaaggcta attgatactt
    55081 aactgctgcc tcacgaccag aggtcacaat catagcctta ccttgaccac ccaattcagc
    55141 cataatatca tgactgataa agtgatccat gataatttca accttttgat tgatattttc
    55201 atcagataat tctacaaact ttgcaatctt acgcttggca agagtcgttt ttagctcagg
    55261 atcttcttcg actgctttat tgagcttgta ataggtctta taagtcgtat agttatctaa
    55321 aacatctaga ataaaacctt cctcaatagc ttgcttcata ctataaacat caaaaggagc
    55381 tttagaacca tctgcttgtg ttgtaccaaa tagctgtaga gttgtcgcct tgggagttgc
    55441 agtgaaggca atgattgaga cattgtcctg cttacctgtc cgagcaatct cctgctcgat
    55501 agcgtccgca acacttactt cttgaatctc atcgatagtt ccatcttctg tatctgtttc
    55561 tgtcaagact tgactaaccg aactcatata ggatcctgtc gttgaactgt gagcttcatc
    55621 aatcaggatg gcaaatttct ttttcgcagt gttccctaca gacatccagt tagattggtt
    55681 gatttgggca aacttatgaa tcgtcgtagc tatgattttt gtatttcctg caatcgcatc
    55741 cgctaagtca ctggaggttt ctttgtcgcc cattaccttg accactccag gcttgtggga
    55801 aatttccttg accgcttctt gtaactgacg atcaactacg atacggtctg taacgattaa
    55861 tacagtatcc acaatatttt gattttgttc atcatggagc gataccaaac tatgagccaa
    55921 ccatgctatg gtattggttt tacctgaacc agctgagtgc tgaatcagat aattactgtc
    55981 tgtatggttg actttcatgt cttctaggag acggctaact gctcttcgct gatggtatct
    56041 cgggaaaatc agggtcttct ttttagaatt atgcttatcc atctcatcca tctcaaaaaa
    56101 gataaaacta tctattaact ggagaatact atccttggtc aagacatcaa gccacaagta
    56161 gtctgtatcg acaccatcag ggttgtgagg gttgccactt cccatctcaa taccttcccc
    56221 tttccccaca ttaaaaggta gaaagtatgt ttcttgtcct ttcaattgcg tcgtcatata
    56281 gacttctagg gtatccactg caaaggaagc caagactccc tgttcaaaac ggaaaagacg
    56341 attcttagga ttgcgtccct tgagctgcct gatagcatcc tgaacagact gaccactggg
    56401 attaaactta agttcgatag caaatagtgc taatccattg ataaagataa caaggtcaat
    56461 gcggtcgctc tcctcgtaaa ccacttcttc cataatagat agacagttga cttggtattg
    56521 ttgaacagcc ttttcattaa aactagtcgc aggtttacga taaagaagac gaagttgttt
    56581 attttcaata aaaactcctt ctttcaaggc gaataaaaag ccacccttga cgatttcttt
    56641 attaatcaga ttgacgattg tctccttact cagtttttta aggagatagt ccatggtctc
    56701 ctcttgggtc tccatcagaa aatcccacag gagttccaca tccatggcta atctaggatc
    56761 gtagcaagta gcgtcccgct gaatatagtc attcttatct ctcaaatctt tgataatcca
    56821 ctgctggaaa tcatagcgct ccttcaagcc caaatttgcc atagcttctc actttctttt
    56881 tctataattc aattaaaaat ttcgttataa ttacaaattt aaagtttaca atgaatttct
    56941 taaaatctaa aaatgataaa actgatattt tattgtactt caatattatc ttttttatct
    57001 ttctgacgtt tatctgcaag tgaatcttcg tattcatttt tagcaatacc caatttcttt
    57061 gcatttgtaa tcacagaaat aaaggcctca agagactctg ctgttagata tatctcttta
    57121 cttttttcat taaaagtaaa aggtgtttga aaaaactgtg ctgataattt attcgctctc
    57181 tttacacatt tccattcata gctcgatgct tcatcattat attttgcaag caaattaatc
    57241 aatttacgat gactttttaa tttagctttt attttttcag attcttcatc agatactttc
    57301 actttaaaat ccgtcgataa tttaaaatta tgagataaaa atttcttata attctcttca
    57361 gccgtgatta ttttcgactc atttaaacca aacataattt cataatcctg aacatcaaag
    57421 atatattgta tagtttcatt gttttcagtt ttttcagcat aacttatgat aaacggaaga
    57481 cttcttccct catctttttc tatatcaact attttaactt ttccagaagt caaagtagca
    57541 atgaatctag tttttaattt cgcaactcga attgatttca aaaaatattt gtactgtaca
    57601 ccatcaattt cttcacaaac tagatacaat cgtatatctt caaagttctt tagaggaggt
    57661 aaatctgttt ctaattgaga tgagactaat tgtattctat ctatttcaga ctggagactc
    57721 tcatcaatct ttctataaaa tggaacttcc gtattattcc cattcgtttc aacattttgt
    57781 aatgactcaa ttgattcttc aaatttttcc tttaaagtta aagttgattc attagaattt
    57841 tgattattag caaattgaat attacctata taattactag cttcatctga gataactttt
    57901 cgaaaatttt tcaatttccc aagtgactta cctcgtccaa cctgccaacc aattgcatat
    57961 atttctacca ttctactctc ctatttcatc atttaatact tcttgatcaa aaaaaaacaa
    58021 atgttcttgc cattgtacca gtatttccta gagtacaaat ccttttcaca ccagaaaatg
    58081 cagccgagtc ttttcgaaag aaaaatatat tgtagttatc ttttgtgact agtaaattga
    58141 caccaaaaat aggtaatatc aagtttggaa aaatatcatt gctaagcatt aataacacaa
    58201 aaaagaaaac aataattata attgctacta gagcactaac tccattcata aatttcaaaa
    58261 ctaaagaggg tacaatggtt gacgatacaa aggatatgaa tcctggattt atttttggtc
    58321 cgtcttgaat atcaatcact ttgccttgag aattattttt caacgtgacc ttaaatacat
    58381 taaaatttaa aacaatattt ttaacaatat tttcttcact cctccgtccg tttatatatc
    58441 cacgtatact gtaaattgat attagcatta tagaaagtaa tactgataac ataagaaaat
    58501 gccacaagtt cctacttaaa taacaaggta acgactcagt ctcttttaat aaaaaatgat
    58561 gaatatctac taatgaaaaa taaatcaata aaaatgctgg aaaaaatgcg gtaaaaaagt
    58621 aagctaaacg aaattttaaa tcagttccaa atagcaatcc tacaccctcc tcttccctgt
    58681 cacataatca taaataagag tttgtcgttg tttgttaata tttttaattt gctgattctt
    58741 gatttgtata aggttatcaa tttgagcggt gttttcatcc aaaagattag caattttttg
    58801 ttgctcaaca aggcttgatg gaaaagtaat tttcatattt tttatatatt cccaacttgc
    58861 tctaggcatt ttactaccat aagtagaagt attaacttct tcaataaaac tatcactttg
    58921 aatagcatag tagagaaaat tcatgtctaa ttctgaagat tgaaacacaa gaaattctga
    58981 actagctgtt gaagggaagg tagctcgcca atattttctc aaatatggtc tcagctttcc
    59041 aaataaaaca tctccaattt cgactacaat attctcactc ttatcaactt gtataccagt
    59101 ttcaacaaat ttcccagttt gactttctat attttctaat cctatgtaag gtatagaaga
    59161 gtctgttatt cttttttcac ttcgagtagt tactaaatat cttattttag aaatctccca
    59221 tccttcaggc acctgtccaa tccagtcgat tcctgaatcc ttcataggga cgtttttatc
    59281 cagtcctttt gtgactgttt cataaatcaa gctagcgcgg tagtctttga gtttttgaat
    59341 ctgctcttcc aatagggctt taaccttatc taactgagct gttttcttgt ctaggaaatc
    59401 agcgatcttt tgttgttcat tttttgaggg aaaggtaaaa gtaaattcat caaatacatt
    59461 ttgatataaa tgtaaaatag tgctagctcc tgaatttgta tagttaaacc acatccaaaa
    59521 ttcatctgat agcaaaacca aatataaaaa ttttctatca atctcatcaa cagtttggat
    59581 tcttaataca ccactattta acgaagcctt atcatcaagc cctgaaataa tagctacttt
    59641 acccaccgta ccatctttcg taattagcaa atcgccattt tcaacctgaa tctgtgaagc
    59701 ttctgaccaa cgtttttcat caatatgtac agctgtttca aaattaatcg ctccattgta
    59761 aaagtcagtt cctgtaatta aatatgggcc ttcctcttta tattcagctg atgttaatcc
    59821 ttgccaacca attctaccat taagctgtgt tgtgaatttt attttagaaa tcacccactc
    59881 ttctggtatc tgtccaatcc agtctatgcc actctctttc atcctagtca tgtttgagtt
    59941 cctccaagag agtctgtagt tctgcttcca aggcatagaa ctcagctaag agcttttctg
    60001 cactttctgg ttcttgatat tgatagaaat agcgggtaaa aggaatttct gctccatagc
    60061 ctttttcctc atcaaaccag tagtgggcgt caggtacatg gggatagacc tcacgcgcaa
    60121 agtaggtttc cacatcctct gtcagcttaa cgatttcact gtccttggtt gtcttatcgt
    60181 agacaattcc atcggcaatc tcatttgcct tgtctttctt cttggttcgg ataacctctg
    60241 ctgtcttatc catttcactc atagctaagg ctagcgcatt gatattagca ggcgtaagct
    60301 taaactctcc cagcaagtcc ttgatgactt ggacaaagtt ctcaaagtca ggataggtct
    60361 tgtcagaact tcccttagca agagctgtca ggatagcttc ttgcttgatc ttgccagcta
    60421 caaagtcctg taattttttc tcatccttgg ctgaacgtgg ttccatctcc agcaattctt
    60481 ggtacttgta ttcatcaaat agtttagcta ggaaaggaac acttttcgct ttctcaattg
    60541 tttcttcact tatctggcca cgacgttgca gaggttgcat aactgtaaac tctcgataga
    60601 gaaactcttg attctcaaag atttttacat ggtcattttc ttgaaaatca tcgtaccagc
    60661 gaaggatctg acggatgtta tcttgggaca actcacggcg tttttgacct agagatttac
    60721 gtagaggaat aaactcctcc gtagcatcga taaactgaac cttgttctgg cgctcaggag
    60781 acttgttttt attataaatc cagatataaa tcccaattcc tgtgttatag aaaaattgac
    60841 ctggaagggc gactatagct tctagcaagt cattctctag gatataacgg cgaatctgac
    60901 tttctcccga tgacgtccca cctgaaaaga ggggagaccc atttgaaatg atggctgcac
    60961 ggccattttc ttctaatttt gtaagagcat gaagatggaa gagtagttga gcatctccag
    61021 ttcctggagt cgcaacaaaa cgaccttgac gaccttctgt tttgtcaaag agttgatgat
    61081 ctttcttaac tgcatcctca actccatcat ccgcatcctt accaccccaa gcttggccga
    61141 agggagggtt agcgatgaca aagctcattt tagtatctgg aaaaggatct ggatctttta
    61201 aggtatccac cttcacaaaa tagtcagagt cttcctgacg aattagcata tctgcacgac
    61261 caatcccaaa ggtttcaggc aaaacttcct gaccaaagag tcgggcagtg gctcctgtat
    61321 tcaactgacg gatatagctt ttagctgtag ccagcattcc cccagttcca gccgccatgt
    61381 ctagtatttt caactctttt ttatcaacaa aaagttcttc gtctgcctca atcaagagga
    61441 ggttgaccat cagagcgata acctcacgag gggtatagtg agaccccgct tcctcatttt
    61501 cagaaaatcg gcggatgata tcctcaaaca tgtatcccat acgcatagag tcgactgaac
    61561 ttggagacaa atcaatttga gagaactttt taataaccgt gaaaaggcga ccactctggg
    61621 ccagggtacg gacttgctct ttaaatttta ggttttcaat gatgtccttg acacgacaag
    61681 aatagccatc cagataggct ataaaattct cctcgattgc atttggatcg ttttgaagat
    61741 tttccaacgt aaaaggacta acattgtagt aacgatagcc tgaaagtttc tccaacactt
    61801 tctcaggtgt attgggattt gctttgtatt gtgctaccac ctgatccttg gttggcagta
    61861 aggcagcttc taaacgagtc aggacaaaca ttggaataat gacatcgcga tacttatctg
    61921 ctcgataagc tcctctaaga gtgttagcga tagaccaaac cgtattgaca tcattagaga
    61981 tttggatatc atttgcttgg aatagtggta atttttcttt gaaactagac atttacttcc
    62041 cctgttttta ttattaacaa ttctcttcat tataccacaa aatacaagtg ataaagcgga
    62101 ttcaagggaa aaaatcgaag tttatatact aaatttcttt actgagtttt tgtcttttgt
    62161 attagggatt ctgtcatttt ctaaaaaact ttatcttaaa cttactcata aaaatttaaa
    62221 aaataaaaag cccacctttc agtagactta gtagtgatct ttgaaggaca aaaaagcgat
    62281 gctatctcca tccatcatat aaatcaagcg attttctgca tcaatacgcc gtgaccaggc
    62341 tccttggtag tcatacttga gtggttctgg ttttcctatt cctgtaaatg aatcactttg
    62401 aatatcctta attagtttat tgattctttt tagtgttttc ttatcctgag tttgccagta
    62461 gcaataatct gcccacgcat cttctgtaaa cttgagcagc attcctcact cctcaataac
    62521 atggacttga gtgcttccag cacggacttg agccattcct cgcaaaacct tgtctgataa
    62581 ctccttattt tgaacgattc tcagggtttc ctgaatactg tcccattcgc tctttgaaag
    62641 aactacaatg tcctcatctg gatttttatt aaccaccgtt aaaggctcaa attcatcatt
    62701 gaccttcttc atgtagtctt ttaaatgatt tcggaatgtt gagtaaagaa ctgcttccat
    62761 aaccatacct cgttttacct cttttccact attatacacg aaaagaaaga aattgtcaga
    62821 aacttgtaca agattttctt ttctatctat ttattcgtaa aaaatctcaa aaagcctacc
    62881 tttcagtaga cttagtttgt ttctattctt attggcactc ttccaaaatt ctgttctgct
    62941 atacttggat ttcctagttg gtaaatctgg tctgcctttt gggtcatagt atcccaaggc
    63001 tctttgccaa ttcgactgac tagattgacc tgacctttca aagacttgag atgttgcctg
    63061 cctttttcag taaatccaag gacatgaatg gcttctgaca agtcactttc tctagcttgc
    63121 accaaaatat aggtcaaaag acgtctgaca cgcgccttgg tgtaacgctt ggtcgcaacc
    63181 accttaacca agtcttccac agactgggct ggtttaatag cctctttaat gcgcacagcc
    63241 atttcttgat taacctgata gatggtggtt aggtctgaat tggacaagat ttgatagcgg
    63301 agcataggaa aatagtcatc ccagctcacc ttactggcct gctcaaagag ggcaacagat
    63361 ggcataaagc gttctaagaa atcttgatct gactggtgct gacggagggc cgtcgccgag
    63421 gcaaagtcca catccttgtc cacagaatgg taaccagccc cctgacgctg aatcggatgg
    63481 agcttgatat ttcgtccagc aaccgccttg gcataagcaa gagcaaggac atgattgggt
    63541 gtattgcctg aaaaatcaag atctgcaaat tctttccaca tggcttgggt tttctgggga
    63601 taggaaagag aatcaggcag tttttccaca aatttctcca tctcagcctc ctgctctgtg
    63661 tataagtcag cgattttttg ataatccaga acttcctccg tcccaaatgc tagagtatca
    63721 atgcccaacc gagccaagat atccacagct ccttgaccga agaaatctgc tgcctgaaca
    63781 ctgactaaaa agggcaattc tactaccaga tctgctccat tttccagcgc catctgggcc
    63841 cgtatccact tatctataat cgctggttct ccacgctgca tgaaatttcc agacatagcc
    63901 acgactttca gtccttcagc ctgttccagc aggtatttgt gtccattatg aaaaggatta
    63961 aactccgcaa taatacccgt gatggtcatg ctaatctcct acttctgcgc gacaaaaaac
    64021 caacgggcac ttgtctctgt cggctccttg tcctcaaaat ccgcatatag tttgaaggac
    64081 ttgaaaccgg cctgttccag caaaatatca taggtcagaa cctcataagt ccgctcctca
    64141 tgcacttcat cgtggcgact aaaggaaccg tccgcctcct tgataaagaa agttagctca
    64201 tggacgatgg agtgaggtgc tgcatcctca taagtatccc agagcatggc aaaatcttcc
    64261 gcattttcat ggtaggaata gcctggaaaa atttcatccg tctggtaagt cgaatgcaca
    64321 tcaaagatga aaactccgtc ttcgttgagg acattataga cttcttgaaa aacgtcccct
    64381 acttccacct catcctgcat gtagcagatt gagtccgagt aacacgtgac aaagtcgtat
    64441 tgacctgcct tggacaaatc cagcatatta ccttccataa aatcaatctt ttgcttggct
    64501 gaagccgctc tcttttcggc aattttcaac atatctgcgc tcaagtccag tccagtcaca
    64561 tcaaaaccag cctgagagaa gcgcactgat tgaattcctg tcccacaagc caattccaag
    64621 agtttctttc tctccttagt ttttggcaaa tgacgcagag aaaaatcagt ccatttgtcg
    64681 tataaactgt catccatgac ctcatcatag accgccgcaa aagtttcata agttgccata
    64741 atcatgatac caagagcctc catggtaaac accattcgcc ctttaccttt ctatccattt
    64801 tcttctaaaa taagcaaata aaacccagtt gactacaact gagttcaatt gtacactata
    64861 gtcttttcgt ttgcttttag tactaggcaa cgagttgcag gcataactgg agttaggcaa
    64921 aacgagttaa cgccgtaata aaagataaag gaaaagacta taaagtttca gataaatcta
    64981 cagaatgcgc ctcatgccat agtttttcta ggttatagtg ggcacgcatt tcttctgaga
    65041 agatatgcac gacaacagca ccaaggtcca gcaagaccca gcctccagtt gcatcacctt
    65101 cgatatggct acctttaaag cctgcttgag ctactttttc acggatattg tcagcgatag
    65161 catccaactg acggctattc attgaactag tgataacaaa gtagtctgtc acgctggtca
    65221 aatcttgtac atcaagtgcg aggatatcct ctgcacgttt ctcatcagcc gctttcacga
    65281 ctagttctag taattctttt tcgttcattt agtcctcttt caaatagtgc acaaaggcgt
    65341 tataggtttc aagggtttgg ggataaatgg gaaatccctg atgagctaga tgctccacgg
    65401 tatgaactgt ttcgtaggcc accgccttat taagcgatag actcgcaatc tcacgcgcca
    65461 cgtccactcc aggaaaggct cgattgtgct cgatatagtc tgcgacgtag ataactttgt
    65521 ctaggtcggt catctgacca gcaccgactg tatggatttc aatggctcgt agaatttcag
    65581 aatcatgcaa attcaaatct tcctgaatct tgtaaattcc gaccatacca tgccagacat
    65641 tattgcccca gtttttgagg tcggggtcta actgataacg gtcaatcaag tctaaaaatt
    65701 cctgatctga cagcttttta gcatagtcat gaagaaggcc tgctagacct gctttctcaa
    65761 catctactcc aaatctctct gctagttcta tggctgcaag ctccacaccc aagcagtggg
    65821 ttaaacgttt ttcaggtaga agctctgcca ttttttccaa caaagcctca cgggagcagt
    65881 tgatatagtc ttgataggcc atcagtagag cccctccttc tctatgtagt ccagtacagg
    65941 ctgaggtagg agaaagttgg gtttccgccc ttgagcaatg aagtcacgca ccatgctgga
    66001 tgagatgtcc atgagaggca catccaccca gataactgga taggaagttc cagccttata
    66061 gcgcgggcgc tgaaccccta caaactgaac catgtcaacc agctcatcaa ttcggtacca
    66121 cttaggcaga tagtccacca tgtcggcacc gatgataaag taataatccg tatctggatg
    66181 ttgctctgtc aagattttca tggtgtcgta ggtgtaggaa atgcccttgc gctccaactc
    66241 aatggtttca atggctaagc cttcaatccc ctcaatcgcc aactcaagca tcttgagacg
    66301 atggtgttca gggatggttt cctttttatc tacgtgagga ggttggtatt caggcataag
    66361 tagaacttgg tccagtccca actgctgccg tacttgatcc gcaacaatga gatgggcatt
    66421 gtgaacaggg ttaaaattcc cccctaaaat cccgatttgt ttgcgttttt tctccttgat
    66481 ttctggctcc aactctacct tggtaaaggg agtcaataat tcgattgcca taggctagtc
    66541 tcctttattt ctctgtaaaa acagttattt ggagtttcgg tcttagattt ctttgacttt
    66601 cttagaaatc ttgcgatttt ctttcttgct agattgttta aacaaaatca agatgcgtcc
    66661 tattttttgg actgtatcca caccgatttc ttcttccaaa atttcagcta cttcgtggat
    66721 gttttcatct gtgttttgta agagagtaac cttgattaat tcacgcgcat caagagcttg
    66781 acggacgctg gttttgattt ggtcgttcag tccatttttc ccgatttgga tgataggttt
    66841 gaggatgtgt gcctggctgt tgaggaaggc acgttgtttt gatgttaatg acataatttt
    66901 cttccttgtt ttttgatagt tattttaggt ggtgagggac ggtcggaact aattttccaa
    66961 agatttcatc tttgaaaaat ggatttcctg acctcacaat tgagccttgg tctcaattgt
    67021 gccccttgcc aatctacaga ttggcaatca caccacggca ataactatcg ctatatgagc
    67081 tcactttgtt cgctcagcga ttttgtttta aataattgct tttcgtatga cgacggcgac
    67141 gccttctggt gcccagacgg cgacttttgc tatgcctgtt acacgaatcc aacctaggcc
    67201 tgagatgact aggtctgtct tatctttaat ggtaaagaca cgctggacta accttgggaa
    67261 atcttctttt tccttgctat ttggtggtgt cagaagagtt cccaggtgct tatcgtagaa
    67321 agtactagct ccttcaagct tgctacggtg gagtttgagt tcattatcaa agaaagcagt
    67381 aaatccttgc ttttctcctg ctataaagtc aaagcgtccc aaaccaccta aaaatagggt
    67441 ttgctcagga ttaagctgat aggtctttgg cttgatttcc tttttaggac tgacatactt
    67501 gaggtttttg gccgtcaagt agtgagccat ctggtggcgg tggataattc ccggcgtatc
    67561 gtaaatataa gatccgtcgt caagcggaat ctctattttg tccaaggttg tccttgggaa
    67621 gcgtgaagta gtgatgacat tctgatcacc cgtgatttct tggataatag cattgattag
    67681 agttgatttt ccaacgttgg tcacaccgac cacatagaca tcgcggccct tacggtagtg
    67741 ttcaatcttg tcaatgactt ccttaatggc atgtttattt tgtgctgaag ttaggaccac
    67801 atcgactgga cgaagccctt cttcatgggc acgtttcatg atccactggc taatcttacc
    67861 agacttaact gacttaggga ggatatcttt tttatttcct accaagagga catcattgcc
    67921 cgagatgaaa cgtggtaaac ctgggatgac agatccatta aaatcaaaga tatcaatgac
    67981 attgacaact aaggcatcac tgtctcccac ctcgtgcaag agcttgagga aatcatcgtt
    68041 cgtcaactgg acatctgtga tttcattgta gtggcggaga cggaaacagc gttggcaata
    68101 gacttcgcca gtctccaaac ctttttcaag tgccgactgg ggggtaaaac caagaccagc
    68161 tttatctgtc gtctgaatgg ttgctccaca accaatacag agaatttctt ccatagttag
    68221 attccttttt tatatgtaat cggtccgtac ttttcagtaa tttttctcat aacacgacgc
    68281 tcacgagttc ggttaatctg cgttttgatt gagtcatgtt ggaccaaggg tttgactaaa
    68341 attgaccgaa tccctgcacg gtgggctgct cgtatatctg tcatgagctg gtcgccaacc
    68401 atgaccactt cctttttgtc atagtggaat tccttcatgg cacggtcaat accaaatgtg
    68461 aagggcttca aggcccagta aacgtaatca atcccaaatt tctcaactgc tcgttgaacg
    68521 cgttttttgg tgttatttga caccacgata atgcgaatgc ccgcgtcccg aaggtcatgt
    68581 agccattgct tcatctctgg cgttccatca gggttgttcc aagcaatgag ggtattatcc
    68641 aaatcgacca aaacagcctt gattccctgc gcctgcaggc ttgggactgt cagatcatag
    68701 actgcttcca cagcaaaatc tggcatataa ttttcaatcg ccattctggc tccttttctt
    68761 aacttttttt cgcaattttc cttagtaaca aggataaaac aatccataaa cctgcactag
    68821 ccaaactgat atagagccaa gcatggggct catctgttaa aggtaaggga acattcattc
    68881 cgaaaaagcc tgtcacgact gccaaaacag ctagcaagac tgaaatgata gtcaaggttg
    68941 tcaaattgtc attcagatta ttgtttagaa tattgttgta agaggctgaa agctgctgta
    69001 aaatctgaga gattaggtct gtcatggata ccagctgatg agcctcaatc atggcatcat
    69061 caaactgttc tctctcaatc tcatcaaaac tacgatacaa ggcatgacct tgaatatgct
    69121 ctaacaaaat ccgattttgt ttggcagctg ccgtcagata aaccatacca gtctccaaat
    69181 cagacagggc aaagaggttt ttcttggtag ttcgctggcg caagaggtca ttgacctcat
    69241 ccctactctt gtccatctgc tcaatgacag gatagtaggc attgctgatg atttccagac
    69301 tggcaaagag aaacttataa atcgaaagcg tgtcatggct ctccagataa cgagtcatct
    69361 gttcaatgac ataggcgttc ttggtattgc taatggtaat caggcgacga tgctccacga
    69421 taaaggtcat gggaaaagtc tcatagtagg ccttgtcctt ttttacgtct aggacattat
    69481 agataaaggt aaccgtccca ctttcacggt ggtagtccat gtgggcgcgc tcgtttctat
    69541 ccagtgcgta ttcaatggtt tccttgtcca aaccgtaaat ttcagaaagg tcttctagtt
    69601 tattcaactt tcctagatct aggtctatcc aggtacaacc attgcccaac tgcttttcta
    69661 aaaccatctt ttctccttat taaactccct ctattgtacc acaaattact taaaataaca
    69721 ggtctagtct gtgcgtgaga aattgctaac aactgtgata tttcggttag ggacaaagtg
    69781 aagggcttgc tcctcgctac gaagctgtgt cgtacgaatt cccacactga caaccttacc
    69841 cgatacagta atcggtccat ttgtcagaac gacctcatct cccacatcca gttgacgttc
    69901 aaagaggatg aaaaagccat tgataacatc agacagaaag ccttgggctc ccataccaat
    69961 cgctacccca gcaataccag ctccagccag caaactagaa actggcaaac ctaaaatcga
    70021 caaaatgcag tagagtaaaa agaaatatag cgtataatta aacacatttt ctagtaaacg
    70081 tgagatggtt ttttggcgtc cgacatcatg acgagacatt tttagagagg ggttgacaat
    70141 tctctgcacc atggtatgaa gcattttttt agcgatataa aatacaatca aaagcagtaa
    70201 aagagaaatg accttggtta gaatattctc gataatggtt gtcacatcta gcttttcaat
    70261 ataagcctga ataaattttt gcatataaaa ctcctttatt tcattatacc atattttcat
    70321 cagtctcatt ctccataaat attcaaaaaa tagacagaaa attcttgatt ttgtctatca
    70381 tttatactat aatcataacc actacacaaa aaggagatta ttatgaaaag aatcattcat
    70441 gcttggaata aggcaagcct tgtcaagcgt atcttgattg gtatgctttg tgggggaatc
    70501 ctaggactga cccttcctaa tctctcaggg attgggctac tcggggattt attcgtcgga
    70561 ggtctaaaag ctgttgctcc tatcctagtc tttgccctcg ttgccaatgc cctttcccaa
    70621 catcaaaagg gacaagatag caatatgaaa acggttgttt tcttgtatat cctagggact
    70681 tttgccgctg ctcttgtagc tgttgtagct agtttcatcg tccctattga aatcacccta
    70741 aatagtgcca ataccgaaat tgctccacca gatgggattg gacaagtcct cagcaacctc
    70801 ttgctcaaac tggttgacaa tccagtcaat gccctcatta ctgccaacta catcggtatc
    70861 ctatcttggg cagttgtttt cgggattgcc atgagagagg ccagcaaaaa tagtaaagaa
    70921 ttactaaaaa ctatcgctga cgtgacttct aaaattgtcg aatggatcat caatctggct
    70981 ccatttggaa tccttggtct tgtttttaaa accatttctg acaagggaat cggaagccct
    71041 gccaactacg gtattttatt ggttctatta gtaacgacta tgctttttgt tgcccttgtg
    71101 gtcaacccct tgattgcctt cttctttatg agacgcaatc cttaccctct agtttggaac
    71161 tgcctccgtg tcagcggtgt gacagccttc ttcactcgta gttctgcggc taacattcct
    71221 gtcaacatga aactctgcca tgaccttgga ctcaacccag atacctattc tgtttctatc
    71281 ccactcggtt ctactatcaa catggccggg gcagcgatta ccattaacgt tttgaccctt
    71341 gctgcagtta acactcttgg aattcctgtt gactttgcca cagcctttgt cctcagtgtg
    71401 gtagcagcta tctcagcctg tggtgcttct ggtattgctg gaggttccct cctccttatc
    71461 ccagttgctt gtagcctttt cggtatttct aacgatattg ccatacaagt tgttgggggt
    71521 ggttttgtga ttggtgtcat ccaagactca tgtgaaacag cccttaactc ttctacagat
    71581 gtcctcttta ccgccgttgc cgaatacgca gcagcccgta aaaaataact cataaaggca
    71641 agcctgctca ggtcttgtct tttacgcttt tattctaact tatcaggaaa ttcttatgtc
    71701 tattagccaa cgtacgacca agctcatctt agctacctgt cttgcctgtt ttcttgctta
    71761 ttttctcaat ctttcctcag cagtttcggc tggaattatc gctctcttga gcctatctga
    71821 tacgcgtaga agtaccttaa aactggctcg caatcgactc ttttccatgc tcctagctct
    71881 ggctatcggt gttctagctt ttcacttgag cggatttcat atctggagcc ttggtctcta
    71941 tcttgccttc tatgtgcctc tagcctacaa gatgggctgg gaaattggca tcacaccaag
    72001 tactgttttg gttagccacc tcttggtaca agagtcaacc tctccagacc ttctagtcaa
    72061 tgaattcttt ctctttgcta tcggtacagg atttgcttta ctggtcaatc tctacatgcc
    72121 ttcacgagaa gaggaaatcc agcactacca cacgctggtg gaagaagccc tcaaactggt
    72181 ctatttagat cactctgacc acctctttca ccaaaccgac taccatatcc actactttga
    72241 gatgagacag cgacaaaggc gtatcctgcg aaatatggcc cagcaaatca atacctgtca
    72301 cctagctgtc agtgagagcc tgattttagc acaactcttt tcaaaaattg ccggtcaact
    72361 gagtcagacc aatcctgctt ctgatttgct agatgaaatt gaacgctatc tggaagtctt
    72421 tcgaaaccgc agtctgccca agacaagaga cgaatttgaa acccgcgcca cccttcttca
    72481 actcctacgt gaagccaaaa ccttcatcca agtaaaagtt gacttttatc aaaaatatgg
    72541 acagtaaaaa ataaaaccac taaaaaacag agcttgctag ctcttttgaa aagtagtata
    72601 attattgcat gcgcaatcat cttgtgacgc aaagactgtc cgtgaatgga ctttcttcta
    72661 tttacaactc taaaaagaaa ggagatacta tgacctattt ggaaaaatgg tttgacttca
    72721 atcggcgtca gaaagagatc gaaaccttgt tagaagacac cattgcccag cagagtgaac
    72781 aaagtctgac cttgaaagag ttctacctgc tctactatct ggacttggct gaagaaaaat
    72841 ctctacgcca gattgatctg ccagataagc ttcatctgag cccgagcgct gtttctcgga
    72901 tggtggctcg attggaagct aaaaattgcg gtctgcttag tcgcatgtgt tgccatcaag
    72961 atagacgctc tagctttatc tgcctgacaa gtgatgggca aaagacactg gcctctctac
    73021 agaaagctgt cgaaacaagc ttggaaactg gtttggattt cttgatttaa gatgatttcg
    73081 gaagaatgtt gcgtgcgcaa gcatttttct tgacattctc ttttacaagg agtaaaataa
    73141 agtcatcatt aaaaaaggag tttttaaatg attgaaatta cctatctaga tgccagcaag
    73201 aacgaaagaa ctgtaacctt cgattcttat gaagactttg atcgttcgca acaagcttgc
    73261 cttatcggcg tcgcagacta ctaccctgtc caaaaattaa cttacaaggg ttatgatttg
    73321 gactatcatg ggacttatgg agatgtcttc ttctatctca tgaaacaaga tttaagccaa
    73381 tataactaaa aaaggagaaa tacaatggca aaggcaatta cagatgcaac attcgaacaa
    73441 gaaacaaaag acggtttggt cttagtagac ttctgggcaa cttggtgtgg tccatgtcgt
    73501 atgcaaggtc caatcttgga caaattgtct gaagaacttt cagaagatgt cttgaaaatc
    73561 gttaaaatgg acgtggatga aaatccaaac acagctcgtg cttttggaat catgtctatc
    73621 ccaactcttc tcttcaaaaa agacggccaa gtagtgaaac aagttgctgg tgttcacaca
    73681 gcagaccaaa tcaaggccat cgttgctgaa ttgagctaat caaacgagag accaagtact
    73741 ttctttggtc tcttttttct tgccctttgc catttttcaa aaaatatgct agactatagt
    73801 agattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact
    73861 gtcctaatcg ttttgtcctg ttcttatttc attttactat ataaatagaa tattacgatg
    73921 tttgggatat gccatcgcta aaaaaactcg atttggtatt ttttagctcc ctaatgggag
    73981 ctttttgcgt tctctgaaca tttcccattt tggaaggagt actatgaaac gtcaatcaac
    74041 cttggtcgtc tttagtggcg gtcaagattc aacaacctgc cttttctggg ccatgcaaca
    74101 ctatgaaaca atcgaagctg tcacctttgc ctacggccaa cgtcatcacc tcgaaattca
    74161 aattgctaga gaaatcgcta aggaacaggg cattcgtcac catatcctcg atatgtctct
    74221 actgggacaa atcactgctc agccagactt tacgacgatt catatttcct acattcctga
    74281 taagctctgt gtcgagtcaa aatccctcaa tatatctatc tatttagcta ccgaaaccac
    74341 ggagatttcc acgaaaactg tatcaacacc atcgggaaag acttggtcaa cttgctagac
    74401 cctcgctatt tagaagtctg gggaaaattc actccgcgcg gtggcatttc aatcgacccc
    74461 tactacaact acggtagacc tggaaccaag tatgacggct tggcagaaca acgcctcttc
    74521 caacacgatc tttatccaga gaaaattgac aaccgttaaa ctcatactca atgaaaatca
    74581 aaaagcaaac taggaagcta gctacaggct gctcaaagca gtgtttgagg ttatagataa
    74641 gactgacgaa gtcagcttaa aacactgttt tgaggttgca gatagaactg acgaagtcag
    74701 taacatatac atacggcaag gttaagctga cgtggtttga agagattttc gaagagtatc
    74761 atacgaaaaa gccctgttcc tcaagatgag gagcaaggct ttttgagttt caattattct
    74821 tctgttccaa ggaaattttt tgcaacaagg gctgcaagaa ctccaccagc gattggtgca
    74881 aggatgaaaa tccaaacttg ttgaagggct gcgccgccca ccaagacagc tggtgccaag
    74941 ctacgagctg ggtttactga aagtccagta atcttcaatc cgacaagaat catcgccatc
    75001 aatgacaaac cgattaccaa accagcaatc gcgccattgc ccttactttc tgaagtcaca
    75061 gtcatgataa ccaagacaaa taagaaagtt gcgatgactt caaacaagaa accaccaaag
    75121 acagtgacac cgtttgccaa ggcattttca ccaaggctag cagttgacat acctgaatta
    75181 gccaagagga agaagactgc gccagaagcg atgaaagctc caacaacctg accaaggatg
    75241 tagtttacaa gttctgaaga tgacaaacgt ttgtttacaa acatagcaat cgaaacagcc
    75301 gggttcaagt gagcacctga aacagttccg attgagtagg ctgccaccac gattgctaaa
    75361 ccaaaagcaa aggcgattcc aaggtgacca aggccatcaa gaccatttcc aaaaacaaca
    75421 gctcctgtcc cgacgaatac aagcatgaac gtaccgatta actcagcaac aaattttttc
    75481 attttctttc tcctcgtaat atataatcat ggggatattt caatcccaag ttttattcgt
    75541 tatcatttga ctattgcaag gttttctaga acaatagagt catggaatgg actcatggtt
    75601 gtttcttttt ctccttgttg cttggacttc attaaaaagt ctgttaccca agccttgttc
    75661 aaacttccaa cacactagct gtttccacag cttgacttct gcatctagta ggatgcaggc
    75721 ggctctgtca ggctgtgata aggattctct tatgcgagga tgttggaaca aggtgtttct
    75781 gggaaacctt acagtagtca aaaaaacttc caaatctaat ggaaaggaga ccttccttaa
    75841 tgaaatgttt tgtcggttta gacgtcagct ctacaaaatt agatgtgtgt atcatgttga
    75901 gtgatactag cacccccgtc actgcttccc tctctaatga cctttctggg gcaacagaga
    75961 ttaagaatca tatccttgat ttgaatcata cctatcactt cgaaaggatt gtcattggca
    76021 tggaagcaac cagtctctac agtttccacc ctgctatgtt cttccatgaa gatagtcagt
    76081 tgaaagaact acatgttgag attatggtcg aacaacctaa taaaatcaag aaatatcggg
    76141 atgctttcga agaaaacaaa aacgatacca ttgatgcttt ctacattgcg gattatttcc
    76201 gtattgagcg attttcacct tctttcttaa aagaagagaa atacatggct ctccaacatc
    76261 tcacaagaac cagactccaa atcatcgagc aattaaccag aaccaaacag cacttcattg
    76321 aaaatatcta ctacaagtgc aataccttgg cttagcaatt caagaaagaa gaactctcta
    76381 ctaacctatg gagttcaacg atgatgacct tgataacaga tgagatgacc ttagacgaac
    76441 ttgctaacat gcctcttcaa gaattagctg attggctcca acaactgggt aaagggcatt
    76501 ttaaggactc tgagaagctt gctcaaacca ttcaagccgc tatcagaggt tcttatcgcc
    76561 tctctaaact ccaacaagat tcagtcaatg tcattctcgg acttctggca gggaaagggt
    76621 ttcaagaaaa ttgattggaa attttttgaa aatcatagag ctattagctt atccctagta
    76681 ttgaaaagac tggatagctt ctttcaagtc atcttgtaaa ctatttctct ggtcgagttg
    76741 tacatagact tctgagagac aggatctgaa attggaaaat ttgtaaaaat cttccctttc
    76801 ttctatcgga aaatcaacaa tttttatcca agaagctact tgctcttgct ccaacttccc
    76861 ttgtaaaatc ggttcataaa gcactctggc taaacgccaa tcttcatcat ctgtaaaacg
    76921 aatggtaatt cttttaaata attgaccaag tatgtcaaat acttcatgaa ctctggtttt
    76981 aggaaagttt ggatgacaaa ccacctctgt cagtaaatcg gctccatgtg caaaagcatg
    77041 aacccaacca tactgacttg aaaaacccct tgtatccttt tcttttgaaa gataatacaa
    77101 gccttgattt aaaaggacat tgcgaatctc tgattttaat ctctgataga aaatcgattg
    77161 ctggttggca tcagcagaca agagatttac ataaataagc gccctaaaag aacgttcaag
    77221 tgttgacaag cctaccttat caatatcttt atctaaccct ccatcagatg aaatcccttc
    77281 agcaatgaaa taaaattgtt cctgtgtaaa tagctcttcc tgaatccctc tagcaaagct
    77341 tgtaaaaaca aggtcatcac gaatttctgg agaaggatct cccaaatgat caagtagcca
    77401 ctggatttct tcctggttat aacttggttt ttcttctgct atttttctaa gtaacttttg
    77461 atacatggtc aatacctcta catttctagc aactgttcaa aaagctgtcc ttaaatgact
    77521 ttagcaattt gtaaaattaa gttaaagaga aaaagacatt tatattcaga gaaacagcac
    77581 atttctgaaa ggatacataa atgatttatt ccatattacc acaaatgaac ttgtaatgat
    77641 agaactttat cacaaaaatc acattcctgt ctcaaaaatt gcgaaaaact agttataata
    77701 aagtgaaata aaaactatac aaattgatta gggaatttaa aacaatttct aacaatattt
    77761 taaaaactga accgtactat ttcaacttcc ataaattaca atattgatag gcacagttcc
    77821 catacctatc caaattcgaa taacgtttag tataaattag aatatgacta caacatcaca
    77881 aataattaga ctatctataa tatctacgat gtaacatata cataggaagc accgttatca
    77941 agagcgccaa ggctatcaac cagataagat gaagatacaa acctgtcacc tcacctcccc
    78001 atataatacg aatcatgcgg gtagcgtgat acaagggaga aaaccaagtc aaatcaccaa
    78061 gtattggggg caaggaagta atgggaaaga aggtatctga aaacatataa agaggacgga
    78121 ttaccaaaac attgtagtaa ttcagaaatt ccctagacgg cgccaagtag gtaaagatta
    78181 gtcccaaaac accaaacaaa taacccacta taaataaaat cagaggaatc aataacatca
    78241 agacatgaaa atgcgctgtg ataagcatgg aaatcagcca aaaaatccca ccgaaaatca
    78301 ctgcacgaat acctgaccag atagcctgac ccaccacaat atcattcgta ttgattggcg
    78361 tcatcaacat agcatcataa gtcttttcaa tcttatactg gataaaggca ttgaccgttg
    78421 tttctgcggt ggccgcagac atggcagtcg cagcaattaa acctgtaatg acaaaatcac
    78481 ggtagagcat accgttaaca tgcgtcaaat aagcaccaac tccaaatccc attgctaaaa
    78541 gataaaagag gggggcgata aggttgggga caattgaaat tttaaataaa tttctaaaac
    78601 tcatgtagtt gcgtaccaca acgtgtccga tggagtgaaa tgataactta aacatgcaag
    78661 tcctccttct ctgtcccagt caaccccaaa aaaagtgtct caaggttgtc agcatcatac
    78721 ttgatgagca agtcttctac agttccttct tctttgatag tcccttggtg gagcatcagc
    78781 accctatctg tcaaatattc aatctcattc atatagtggg aagtaataat gatggaaaca
    78841 cctaattcct tcaactccaa aagtttatcc caaataatat tgcgggattg aatgtctaaa
    78901 ccaactgtcg gttcatctaa aataataata tcaggccgat tgatgagagc tcttgccaag
    78961 acaagacgtc gtcgcatccc acccgacagc tgattcacca tcttttgcgc atgtttgctc
    79021 agttgaacaa aatccaagag agaaccgatt ctcttcctaa gttcgacaga tgagatacca
    79081 taacatagac cgtgagcaaa aagattatca taaacattca aggtcatgtc cagcatatcc
    79141 tcctgcccta caatacccag acaagattta ctcttacgac gattggtttc aatatttttc
    79201 cccaagatac ccaaacactc tccttctccc aattcaaagc taattccctt gacagcttca
    79261 taagaaccat attgcttttt tagattttta acacttaact tcttcactct ttctttcccc
    79321 cacaaataga gcatgttgga tactttgtta attcatcaaa atgttgttcg aatgttataa
    79381 agtcaattga gaatctttta ttaaatgtta gcaatgcttc gtatccccaa aaaatatatc
    79441 ttaaaatttc aaacgaaata aaataccctt gaaatagaca agcaggacct aaagcaccat
    79501 tcggagttct gaacatctct agttccaatg aatttgtcat tgtacgaacg gtctccaact
    79561 cttcagcata ctcaggaatt ttttccaaat cctctaaaaa ctgacagtaa tagcacgctg
    79621 ctttatacgg aataattgaa tatactttcc catttttctt accaaccaca gcagacagac
    79681 ataatttatt gtattgaaca caggcttcat tgacccaaaa atcaatatag cctgttggat
    79741 aatctgcaac atttactacg atatcacatt ttgaagtttt tattaactca tcgacatcct
    79801 cttttgaacc tatctcttta tcaagtacct caaattcaat taaaggatta aactttctaa
    79861 gcgactcttt tgcagcctct acttttcttt ttccaatatc agatgtcgaa tacaaaattt
    79921 gtctattgag attactagct tcgaccgtat caaaatcaac tgctgtaata tgccctatac
    79981 ctaattcagc caatgctaga cagatattac ttcctatacc accaatacct aagagcaaaa
    80041 tacgcgtctt ttttaatttt aactgataat catactttgt taaagataat gtatctaaag
    80101 tattaaaaaa gttaagattt acggaatatc tatccaattc ttctgaagtt aattcagttg
    80161 tagtaacaaa attatcctcc aaatacccta gtgtatctag taaagaaata ctttcttcta
    80221 cctcattagg ggacaagcta tcaactaagc tacaaatttc attgattgtg tattgtccat
    80281 cgagaagctt aatgagctga gtatacttct catccagatt ctcaatctca ataccataat
    80341 cttttcctat acctaatcta attttatcct ttaaaaatag gacactatga atatctttaa
    80401 ttttaggtaa attcaattct atttcctcct aaaatagaca aaaagaatgg aaaaatccat
    80461 tcacttttga aaaaatgttg agaatgtaat cttaagatta acgtccttca actgtggata
    80521 ctgctgcaat tacttttgta attttacctc catttaaact cagacaataa aatttaaaat
    80581 attctctagt aaaacatttt taaaatctat ttttcttgtg ctttaattat agtataataa
    80641 aagatagaaa atcatcgata tatgaaattt ggagaaaatt tttatggaac cagatatttt
    80701 catcatcaca aaactcttat cagacccttc tcggatgcac attttagata ttctaatgga
    80761 tggaaaagct cacacggtta acgaaattgc cagctttacc aaaatcaagc aacatactgt
    80821 cagctatcac ctcaaattac ttaccgaagc gcaggtaacc actctacaaa cctatggacg
    80881 ttttcattat tattctttaa aaagtgctgc cattgcagaa atgctggaat ttctcagctt
    80941 ctactctcct cagcgtgatg tcaaaagtta taaacaacac attcacaaaa aggaattaaa
    81001 agtcgctcgc acctgctatg accatattgc tggtgagctt ggcatttcca ttaccaatta
    81061 tctcttgcaa gaaaatctcc tcagcgaatc agaaaaagac ttccaactca ctgaagctgg
    81121 gaagtcttat ttccaaagaa aattacacat tgatacggat gaattgaaaa agaaaaaacg
    81181 gaaattttgc cctaaatgtt tggattggag cgaacgtaaa aatcatgtcg gcggagctct
    81241 cggcaatgct cttttagaat ttttcagtga aaaacaattg gtcatccctg cacaaacgcc
    81301 acgttcactt accattacag agcagggcaa agaattcctc gaaaaggaat gggggattta
    81361 aacatggaat tttaagcaaa taactgtcca tacccattct ataacaacct ctctatcccc
    81421 ttactccccc aactcagcac tgtaggcgat aatctggtca actgtgtcag acaagaattg
    81481 gatggtatca cggagtggtt tgtctgttga aatatcagca ccgataatca tggctgactc
    81541 aagtggtgtc ttgctaccac ctgatttaag gagattgagc cagtcttcag ctccagtttc
    81601 tgagttttta agatgaaggt aaccagcagt cgagataact agtcctgctg agtaagtgta
    81661 actatacaag cccatatagt attgagcttg gcgcatccaa gtcaaagctg catcgtcgtc
    81721 gatttcaatg gcatcgcccc aaaaatctgt caaaacttcc ttcataatgc tgttgagttt
    81781 gcttgctccg aaggtttctc cttcttcaat caatgtatac accttacgct ggaaggctgc
    81841 ttccaagagg tgggtgataa agttatggaa gtaggtgtct gtcaagcgat gagccagagc
    81901 gaagcgtttt tgacgtgggt cattagactg gttctctaag taatcactga gtagcaattc
    81961 attgaaggtc gacggtgctt caacataata ggtcgacatg tgggcgttga aatagctttg
    82021 gtgattgtct gaaaagatga attgaccaga atgcccgatt tcatgaatca aggtatagac
    82081 atcgctcaaa cggcctgtcc agctcatgag gacataaggg tgtacgcgat atgggtccgc
    82141 cgcataacca ccggaatcct tgccactgtt agcagcaaag tccacccagc gctcttcttg
    82201 gtaacgagca acttcctgac aatattcttg ccccaaaggt tctaccgact tcatgaccaa
    82261 atcataggca tcgtcaatag tcacttcagg attcagggcg ctgtccaagt ccaatttcca
    82321 gtctgcaaag gtcatctttt caagaccatt taccttggca acatgcttga ggtatctctg
    82381 agcgactggt gcaaagtcct tcatgatgag gtcaatctgg cgatcaaaca tgacacggtc
    82441 cacttcttgt tcagctagaa gataatcaaa gacagagtcg tatcccttca tatcagccaa
    82501 gagtttttca gacttgacct gagccagata ggctgctgca gccgtatttt ggtgcttacg
    82561 aagtccctct gagaaggaac ggaaggattt ctcacgaacc tcagcatcct cgtgattttg
    82621 gtagaaattc tcataggtga caaagctgtt tttgtaggtc ttgccatggg cttcaaagtc
    82681 agccatttca aaatccccag ctcgcatctt agtataaatg tcctgcggac tatagaaaac
    82741 ttcaccgaga ttggctaagg ccttctccac atcagcccct agatagtggg cttttttgat
    82801 tttggcctga cgaatagctg ccgtcaagtg aggcaattca cccaaacggt ccaagacttc
    82861 ctcgtctgct accaccaagg catcgtcaaa gaaggtcaag gctacgctgg catctgtttc
    82921 aaattccatc ccagcttggg caatattggc aaattcgtca ttgctatagt ccgtcgtctg
    82981 aggcataaaa ccatagttgc caatatggct catctgaatg tagatctgtt ccaattccgc
    83041 aaaggccttc tcgaaatcct caaaagtgtg aagattgccc ttgtaatcac ggctaaactg
    83101 gttgatgtct tcgcgagctt tctcgattgc acgcaagaaa tcctcacggt cttggtatag
    83161 ggctgttaag tcccagagtt ccttctctgg aaattctgaa cggtgttttt gttccatttt
    83221 cttcctcttt atttctctaa ttctactaaa acactaaggg ctgataaagc gtaaagcggt
    83281 gctgtttctg ctcttagaat gcgagggcca agtcctgcca aaacagctcc cttagcttca
    83341 aaattttcaa tttccgcagg tgacagacca ccttctggac caaagataaa gagcagtttg
    83401 gctcctgttt caagaccagt gactgcttgc agaagcgcag cggcttctcc ttctttagct
    83461 gattcttcat aggctactat gatagagtca aactggtcca gctgagctag aaaatctgct
    83521 tttttctcga aaagtttaat acttggtaca atattacgct tgctttgctc ggctgctcca
    83581 agggcaattt tttctagttt ttcaactttt ttacccaatt tcttgccatc ccacttggca
    83641 actgaccagt ctgcaggaaa ggcccagatt tggctagcac ccagttcggt tactttttga
    83701 gcgatgaact ccagcttgtc tcccttggga aatccagatg cgatggtcac ttggactggt
    83761 agttccacat tgtcatttaa ttcttggacc aactcaaact gacgattttc catatccagc
    83821 acgcgcgcca agcgcttgat gccatcatca aagactaagg taacctcatc ctcttctttc
    83881 aagcgcataa cctgaaacat atgcttactg gtttccttgt cctcgatagt gacaggagaa
    83941 atagcactgc cttttacaaa atactgctgc atgctagcct ccaatcacac cagagatatc
    84001 cttggttttc ttaaagacac aggtattcca ttccccttga accatgtgag tttcgaggaa
    84061 aaatccagct gattcagccg actcgcgcac catgtcccac ttatccttga taatgccact
    84121 catgatgagg tagccttcat cctttaccaa gcgataagca tcctccgtca gatgaatgag
    84181 aatatccgcc aagatattag ccacgatgac atctgcttca atctcaactc ccttaagcaa
    84241 gtctcctgct gctacatgga tattttccat accagtgttg agctcaatat tttcctgagc
    84301 gacacgaacc gccacatcat ccaagtcata ggcgaaaatc tccttggcac ctaggagtga
    84361 gcttgcaata gaaagaaccc ctgaaccagt ccctacatct agcactgttt cgccaccacg
    84421 aagaacctgt tccaaggcaa agaggctcat cttggttgtt gggtgggtcc ctgtcccaaa
    84481 ggccatacca ggatccagct tgataatctt ttctcctgct gttgcctcat agtccgtcca
    84541 tgacggtacg atggtcaggt catgggtgat gcgtgccggt gcataatact tcttccagtt
    84601 gtcagcccag tcttcctcag ccaaggcagt cgtgcccatc ttgacttctc ctaggtccat
    84661 aaagtcggtc aattctgcca gacgagcctg caaatccgct tcaactgctg ctacatcaac
    84721 cgtttcaggg tagtaggctg tcactacgat ttcttcttgc tgctccacct ctgggaaaat
    84781 ctcgccgaag cggtccacat ttcccacata gtccatactg tcttcgattg cgactccttg
    84841 cgctcccagc tcaatcaaga gattggaaac caattcctcc ccctcacgct tcactgtaac
    84901 ttttaactct tgccatgttt ccatcattaa gataccaagc ccgtaaaaca caaaaccaaa
    84961 ataggaaatt ctctgaagac gcttgtgtct aagagaagtt tatctttttg gcacagtgtt
    85021 tagggcgggt tcagtttaga aatttaactg aaccatcctt tctaatcact tacttttaaa
    85081 taatctttta atctctcttg caactgaggc acaacttgac tggaactaag aaattcctca
    85141 acattcatca gctgatagcc ctgtccttca tctccaaata cgatactgtc aaactggttc
    85201 tgtgtcaact gaccaactag aaaaacggac tgtttatctg caaaaagcat acttgggtaa
    85261 accttactcc aaagcagaca atcttcagtc agatgaatgc ccagttcttc ataaacttca
    85321 cgcgctgcgc actcaaaagg actttcatca ccttcacgtc c
//
LOCUS       DAVFJR010000005        84010 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVFJR010000005 DAVFJR010000000
VERSION     DAVFJR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.005"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(86..1402)
                     /locus_tag="VU722_000453"
     CDS             complement(86..1402)
                     /locus_tag="VU722_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU1771493.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            1596..2822
                     /locus_tag="VU722_000454"
     CDS             1596..2822
                     /locus_tag="VU722_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU1771494.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            3021..4595
                     /locus_tag="VU722_000455"
     CDS             3021..4595
                     /locus_tag="VU722_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1771495.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFVDE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYCKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            4859..5647
                     /gene="codY"
                     /locus_tag="VU722_000456"
     CDS             4859..5647
                     /gene="codY"
                     /locus_tag="VU722_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU1771496.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDNYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            5647..6222
                     /locus_tag="VU722_000457"
     CDS             5647..6222
                     /locus_tag="VU722_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU1771497.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTGGRNLYGDLGIFYQEHDSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFSLGHFKNTLGAKLVDENLNELSE"
     gene            6304..6389
                     /locus_tag="VU722_000458"
     tRNA            6304..6389
                     /locus_tag="VU722_000458"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6338..6340,aa:Leu,seq:aag)
     gene            6672..7802
                     /gene="ugpC"
                     /locus_tag="VU722_000459"
     CDS             6672..7802
                     /gene="ugpC"
                     /locus_tag="VU722_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU1771498.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            8303..9061
                     /locus_tag="VU722_000460"
     CDS             8303..9061
                     /locus_tag="VU722_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU1771499.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDAWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            9148..9660
                     /locus_tag="VU722_000461"
     CDS             9148..9660
                     /locus_tag="VU722_000461"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU1771500.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            9842..10786
                     /locus_tag="VU722_000462"
     CDS             9842..10786
                     /locus_tag="VU722_000462"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU1771501.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQNTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDEDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            10795..11472
                     /locus_tag="VU722_000463"
     CDS             10795..11472
                     /locus_tag="VU722_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU1771502.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            11571..12329
                     /locus_tag="VU722_000464"
     CDS             11571..12329
                     /locus_tag="VU722_000464"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU1771503.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIASP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLSAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            12367..13871
                     /gene="lytC"
                     /locus_tag="VU722_000465"
                     /pseudo
     CDS             12367..13871
                     /gene="lytC"
                     /locus_tag="VU722_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            14367..14885
                     /locus_tag="VU722_000466"
     CDS             14367..14885
                     /locus_tag="VU722_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU1771504.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            15015..15521
                     /locus_tag="VU722_000467"
     CDS             15015..15521
                     /locus_tag="VU722_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU1771505.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            15521..15691
                     /locus_tag="VU722_000468"
     CDS             15521..15691
                     /locus_tag="VU722_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771506.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            15723..16955
                     /gene="clpX"
                     /locus_tag="VU722_000469"
     CDS             15723..16955
                     /gene="clpX"
                     /locus_tag="VU722_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU1771507.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            16964..17551
                     /locus_tag="VU722_000470"
     CDS             16964..17551
                     /locus_tag="VU722_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU1771508.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            17562..17942
                     /locus_tag="VU722_000471"
     CDS             17562..17942
                     /locus_tag="VU722_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU1771509.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            17994..18884
                     /gene="rapZ"
                     /locus_tag="VU722_000472"
     CDS             17994..18884
                     /gene="rapZ"
                     /locus_tag="VU722_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU1771510.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKNLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NYPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            18881..19858
                     /locus_tag="VU722_000473"
     CDS             18881..19858
                     /locus_tag="VU722_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU1771511.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQIILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            19855..20766
                     /gene="whiA"
                     /locus_tag="VU722_000474"
     CDS             19855..20766
                     /gene="whiA"
                     /locus_tag="VU722_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU1771512.1"
                     /translation="MSFTVAIKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(20854..21981)
                     /locus_tag="VU722_000475"
     CDS             complement(20854..21981)
                     /locus_tag="VU722_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU1771513.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSENVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(22131..22727)
                     /locus_tag="VU722_000476"
     CDS             complement(22131..22727)
                     /locus_tag="VU722_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4190 domain-containing protein"
                     /protein_id="HEU1771514.1"
                     /translation="MKQERKVLGILAIIFGALALLGSWMPIINNFSFILAILALIFGL
                     IGFAVNRKRPKTLAIIGTVLAVVSIAIVLVTQAMYAKSLKELGKNVEETVSSVSSSIE
                     SSQKEEDAKFNWTKEQFDALQVGDIINYGAGGTNYDDVASVHGEPNNVTTSSVNDHDS
                     KTVSYTSTGSKYKSVILSFSKQDDGSFLLTSKVSSGLE"
     gene            complement(22779..23159)
                     /locus_tag="VU722_000477"
     CDS             complement(22779..23159)
                     /locus_tag="VU722_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU1771515.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTLSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLSLVN"
     gene            complement(23170..23337)
                     /locus_tag="VU722_000478"
     CDS             complement(23170..23337)
                     /locus_tag="VU722_000478"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771516.1"
                     /translation="MNHVQVKRPKENNSEYDYMLRLSNESIHQFEQKKKRQESQLKSY
                     PAIKSYYRVAN"
     gene            complement(23334..23810)
                     /locus_tag="VU722_000479"
     CDS             complement(23334..23810)
                     /locus_tag="VU722_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771517.1"
                     /translation="MTLAKLHFNDQGNLNGGILTNISLAQIQSTLVDNFPNSTTRTRN
                     FQALSTFLKNLDSNIITRIWLDGSFCTQKENPKDIDVLLFFKHSPDIEKYLKDIKEKA
                     STCLDIYQIGDKDHIEKTRPIYSHMAHNETYWMGQFGFDRNRNHKGIIELKTENLK"
     gene            complement(23904..24086)
                     /locus_tag="VU722_000480"
     CDS             complement(23904..24086)
                     /locus_tag="VU722_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU1771518.1"
                     /translation="MYRLVYESKAQKQLKKLDGATRRKIISWMTKNVDNTSNPYQHAK
                     LLKGNLSGYCRYRVGD"
     gene            complement(24086..24325)
                     /locus_tag="VU722_000481"
     CDS             complement(24086..24325)
                     /locus_tag="VU722_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771519.1"
                     /translation="MTITINFTEKNSYITDYLNKHGINTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPNPKTYTTDELLESLGMTREDIA"
     gene            complement(24325..24693)
                     /locus_tag="VU722_000482"
     CDS             complement(24325..24693)
                     /locus_tag="VU722_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1771520.1"
                     /translation="MFQTFDRIKELAKKQGLSINSLEEKLGYSRNTIYNLKSSKPSTE
                     RISEIADYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            24994..25185
                     /locus_tag="VU722_000483"
     CDS             24994..25185
                     /locus_tag="VU722_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771521.1"
                     /translation="MPNMDGGRQKIRDYLKEHNLTMATLAVQYSMARQDVTNILNGKL
                     KNPQANQFIARVIEDFKIR"
     gene            25212..25391
                     /locus_tag="VU722_000484"
     CDS             25212..25391
                     /locus_tag="VU722_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771522.1"
                     /translation="MEEDIRVHMPYEVFKNLLVRAGRIKREEGKQITWTNNTAPFTKE
                     QRREIDELYEQFAED"
     gene            complement(25367..25918)
                     /locus_tag="VU722_000485"
     CDS             complement(25367..25918)
                     /locus_tag="VU722_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771523.1"
                     /translation="MSEVFTTTLISVGATVLTNLIIHGFAYQQKKIENKNKLEEKKVD
                     FLNTQLSQDRDLYISTFQNFASISGKTVSYVESRLDDAPPIDLDIITNFDDIFYKTYL
                     FLDSDEEQKKFIYFRNVLRYQAGYPHPDGLYIWDVQFEEQSYDPDTIEEPRYIFDRLN
                     ECLLIANKHINDKLHIQSSANCS"
     gene            26166..26510
                     /locus_tag="VU722_000486"
     CDS             26166..26510
                     /locus_tag="VU722_000486"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771524.1"
                     /translation="MTDRELFKLPEDYVESTGLDKITFEVPFELFTKILKGYGHKLAW
                     EDFRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTKKQKRLH
                     KLAQNLLHRMKG"
     gene            26677..26880
                     /locus_tag="VU722_000487"
     CDS             26677..26880
                     /locus_tag="VU722_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771525.1"
                     /translation="MRPKRYPYSGKKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYKAIHDTSQVTQ"
     gene            complement(27035..27202)
                     /locus_tag="VU722_000488"
     CDS             complement(27035..27202)
                     /locus_tag="VU722_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEU1771526.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            27319..27462
                     /locus_tag="VU722_000489"
     CDS             27319..27462
                     /locus_tag="VU722_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771527.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            27459..27629
                     /locus_tag="VU722_000490"
     CDS             27459..27629
                     /locus_tag="VU722_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771528.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAIEARLNQKADQLKLDDLD
                     LEIISSRLEKVI"
     gene            complement(27622..27861)
                     /locus_tag="VU722_000491"
     CDS             complement(27622..27861)
                     /locus_tag="VU722_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771529.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMANPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            27980..28252
                     /locus_tag="VU722_000492"
     CDS             27980..28252
                     /locus_tag="VU722_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771530.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETRKKMRSAG"
     gene            28249..28443
                     /locus_tag="VU722_000493"
     CDS             28249..28443
                     /locus_tag="VU722_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771531.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            28440..28631
                     /locus_tag="VU722_000494"
     CDS             28440..28631
                     /locus_tag="VU722_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771532.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            28643..28984
                     /locus_tag="VU722_000495"
     CDS             28643..28984
                     /locus_tag="VU722_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771533.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            28985..29215
                     /locus_tag="VU722_000496"
     CDS             28985..29215
                     /locus_tag="VU722_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771534.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            29229..29951
                     /locus_tag="VU722_000497"
     CDS             29229..29951
                     /locus_tag="VU722_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU1771535.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKTGIGLTKLTNKIREVEKNG"
     gene            29944..30426
                     /locus_tag="VU722_000498"
     CDS             29944..30426
                     /locus_tag="VU722_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEU1771536.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNITGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAKLVRTEKLVIK
                     "
     gene            30426..30785
                     /locus_tag="VU722_000499"
     CDS             30426..30785
                     /locus_tag="VU722_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771537.1"
                     /translation="MELMNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPECKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            30785..31270
                     /locus_tag="VU722_000500"
     CDS             30785..31270
                     /locus_tag="VU722_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771538.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            31233..32426
                     /locus_tag="VU722_000501"
     CDS             31233..32426
                     /locus_tag="VU722_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEU1771539.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YRKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKSV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            32444..32761
                     /locus_tag="VU722_000502"
     CDS             32444..32761
                     /locus_tag="VU722_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771540.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            32761..33587
                     /locus_tag="VU722_000503"
                     /pseudo
     CDS             32761..33587
                     /locus_tag="VU722_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            33607..34113
                     /locus_tag="VU722_000504"
     CDS             33607..34113
                     /locus_tag="VU722_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771541.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            34286..35107
                     /locus_tag="VU722_000505"
     CDS             34286..35107
                     /locus_tag="VU722_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEU1771542.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTASEIE
                     RFWDGYPNANIALRTTNFFVIDIDKHGKENGFESLKKWEHLNLIEPTLQAKTASGGKH
                     LLYFKRDDEPITQMIKFLPGVDIKAHENNYIIVAPSATENGQYEWDLEKSAEGGTIVT
                     PSRDLIRAIKKQYGKTHGYRYDGKDGLRDLARRSQTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            35110..36447
                     /locus_tag="VU722_000506"
     CDS             35110..36447
                     /locus_tag="VU722_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU1771543.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKN"
     gene            36747..36902
                     /locus_tag="VU722_000507"
     CDS             36747..36902
                     /locus_tag="VU722_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771544.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            36899..37372
                     /locus_tag="VU722_000508"
     CDS             36899..37372
                     /locus_tag="VU722_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU1771545.1"
                     /translation="MNKQELIEKYKELENSSFDIAAIVVCQLILKDLEQLDEPKPVKV
                     QQFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWIFGYEVEEEKRYT
                     VVTKATKQPLYYNAMDKKLFFSMGGLATKFTRKQLKEADLGWVFDCEGIEIEEVE"
     gene            37372..37545
                     /locus_tag="VU722_000509"
     CDS             37372..37545
                     /locus_tag="VU722_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771546.1"
                     /translation="MEDEQNILETQLILGKQVLEIVLDLLKDDSKIGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            37608..38498
                     /locus_tag="VU722_000510"
     CDS             37608..38498
                     /locus_tag="VU722_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU1771547.1"
                     /translation="MKFLNLFAGIGGFRLGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRRERTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAINSYHENNHLSDGFRIRKLTPKECWRLQGFPDWTFDKAQEVNSNSQLY
                     KQAGNSVTVNVIAAIAKELS"
     gene            38599..39015
                     /locus_tag="VU722_000511"
     CDS             38599..39015
                     /locus_tag="VU722_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771548.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLKDKNGKEVFVGDIIKCTRGCLHEVYLEKEYGGTFIGGM
                     PSIYLKGLLNGYAWTEDEEIIDNVYENPELLEVTHE"
     gene            39008..39187
                     /locus_tag="VU722_000512"
     CDS             39008..39187
                     /locus_tag="VU722_000512"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771549.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            39208..39522
                     /locus_tag="VU722_000513"
     CDS             39208..39522
                     /locus_tag="VU722_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771550.1"
                     /translation="MTLFDEMQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDERTLEALRELLGAGFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
     gene            39597..40058
                     /locus_tag="VU722_000514"
     CDS             39597..40058
                     /locus_tag="VU722_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU1771551.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            40083..40165
                     /locus_tag="VU722_000515"
     tRNA            40083..40165
                     /locus_tag="VU722_000515"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40114..40116,aa:Tyr,seq:gta)
     gene            41290..41730
                     /locus_tag="VU722_000516"
     CDS             41290..41730
                     /locus_tag="VU722_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU1771552.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDEQLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     INVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            41708..43006
                     /locus_tag="VU722_000517"
     CDS             41708..43006
                     /locus_tag="VU722_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU1771553.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWIKRVFFDEETSRADTFATTTTYRCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDLANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            43018..44487
                     /locus_tag="VU722_000518"
     CDS             43018..44487
                     /locus_tag="VU722_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU1771554.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIRNTESSHLKKLKSYYL
                     GKHAILKHTRRNVNAPNYQTVANHAKDIADMATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGLTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMSLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPTDGQGRKAGRPVR"
     gene            44396..45947
                     /locus_tag="VU722_000519"
                     /pseudo
     CDS             44396..45947
                     /locus_tag="VU722_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            46261..46785
                     /locus_tag="VU722_000520"
     CDS             46261..46785
                     /locus_tag="VU722_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU1771555.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            46808..47833
                     /locus_tag="VU722_000521"
     CDS             46808..47833
                     /locus_tag="VU722_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEU1771556.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKVVNRAKAWKTGTTYKKGESVTHADKVYVAVKDISNSATAPDTDTTNW
                     KEKTGKK"
     gene            47843..48031
                     /locus_tag="VU722_000522"
     CDS             47843..48031
                     /locus_tag="VU722_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771557.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNFASNGVA
                     ISDVLEEILPEPEFFEED"
     gene            48033..48344
                     /locus_tag="VU722_000523"
     CDS             48033..48344
                     /locus_tag="VU722_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU1771558.1"
                     /translation="MSIELLKKMTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            48325..48663
                     /locus_tag="VU722_000524"
     CDS             48325..48663
                     /locus_tag="VU722_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771559.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            48638..49150
                     /locus_tag="VU722_000525"
     CDS             48638..49150
                     /locus_tag="VU722_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU1771560.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQI"
     gene            49150..49518
                     /locus_tag="VU722_000526"
     CDS             49150..49518
                     /locus_tag="VU722_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771561.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWENFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            49521..49934
                     /locus_tag="VU722_000527"
     CDS             49521..49934
                     /locus_tag="VU722_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU1771562.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELKYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            49939..50319
                     /locus_tag="VU722_000528"
     CDS             49939..50319
                     /locus_tag="VU722_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771563.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKGKKASKKKMTVVE"
     gene            50358..50708
                     /locus_tag="VU722_000529"
     CDS             50358..50708
                     /locus_tag="VU722_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771564.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIAELWEYAPDLFVEEKQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            50695..51240
                     /locus_tag="VU722_000530"
                     /pseudo
     CDS             50695..51240
                     /locus_tag="VU722_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52580..54301
                     /locus_tag="VU722_000531"
                     /pseudo
     CDS             52580..54301
                     /locus_tag="VU722_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            54310..54660
                     /locus_tag="VU722_000532"
     CDS             54310..54660
                     /locus_tag="VU722_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771565.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMLTQEEMSQLLNAVSAVFFEVSYPDPVKGQTTGTFYVGDRTAPSYSFTEK
                     FKPWSGAKFNLVER"
     gene            54665..57862
                     /locus_tag="VU722_000533"
     CDS             54665..57862
                     /locus_tag="VU722_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU1771566.1"
                     /translation="MDALIRRQFDRAMFAKDRTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDILHPEIGLLVGTTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLYGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDSDQKVDKIKKDFNDQVELAKARAEEVKQE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEVKRIGLDSVARLGAFKSQ
                     TTSAQTALSGDLDALKQTVTSEVNQASEYRRTTTEVLSRMTGQMDGFATKSEVRQDVA
                     GLTETFAKLKTDTNNLISGAKSEITLAKTEFQKTADGLSAKMSAVERYVNQDGQRQEA
                     LQRYTREESARQVSAVREQISRDYVGKSAYQEDVRGLERRFSAISTQTNNDIARKIAQ
                     YKQTVDGQFASITSQIAGKANQTDFQRVKETSKLYERILGNSKNGIANTIARMAMTHQ
                     LFQVEVSKNDHLKTVQRQLAGSWSVQNINSAGDLISGINLGANGHNRFVGKLTHITGE
                     TLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEAVTADKVRFDAAFIRKMTANDAFI
                     DQLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTIGRFAQGRGRWISGINQFSVGMGN
                     GEGGGYNGENTAFWANWGYSWNSPGPNAWYVTTSGNMYCRNGADFHGKVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVFGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSD
                     RRLKENITDTAVKALDKINRLRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPEN
                     PDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            57859..57975
                     /locus_tag="VU722_000534"
     CDS             57859..57975
                     /locus_tag="VU722_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HEU1771567.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTDRLENLENERRTA"
     gene            57956..58159
                     /locus_tag="VU722_000535"
     CDS             57956..58159
                     /locus_tag="VU722_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771568.1"
                     /translation="MNAEQLNQALQMTISEMSTTSTNSMITSNVLSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            58162..58512
                     /locus_tag="VU722_000536"
     CDS             58162..58512
                     /locus_tag="VU722_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771569.1"
                     /translation="MAKTIQNTDNLLDLTKITEPFDLASALRYMKESGEFIRCKNVND
                     DFYMYRDVQKRPVFVNGRRQFKDVETVWAFNQWGGTITTINVAILLNQEFYIMKFDAE
                     GNPDWTDPTVEPKE"
     gene            58521..58820
                     /locus_tag="VU722_000537"
     CDS             58521..58820
                     /locus_tag="VU722_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771570.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            58824..59156
                     /locus_tag="VU722_000538"
     CDS             58824..59156
                     /locus_tag="VU722_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU1771571.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            59160..60116
                     /gene="lytA"
                     /locus_tag="VU722_000539"
     CDS             59160..60116
                     /gene="lytA"
                     /locus_tag="VU722_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU1771572.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(60369..61337)
                     /locus_tag="VU722_000540"
     CDS             complement(60369..61337)
                     /locus_tag="VU722_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU1771573.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFTPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            61473..62330
                     /locus_tag="VU722_000541"
     CDS             61473..62330
                     /locus_tag="VU722_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU1771574.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKTIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            62317..63096
                     /locus_tag="VU722_000542"
     CDS             62317..63096
                     /locus_tag="VU722_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771575.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEALPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            63120..64472
                     /locus_tag="VU722_000543"
     CDS             63120..64472
                     /locus_tag="VU722_000543"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU1771576.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGELLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     KNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKKTGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            64546..64920
                     /locus_tag="VU722_000544"
     CDS             64546..64920
                     /locus_tag="VU722_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU1771577.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            64922..65770
                     /locus_tag="VU722_000545"
     CDS             64922..65770
                     /locus_tag="VU722_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1771578.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASSQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            66047..66814
                     /locus_tag="VU722_000546"
     CDS             66047..66814
                     /locus_tag="VU722_000546"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU1771579.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            66826..68010
                     /locus_tag="VU722_000547"
     CDS             66826..68010
                     /locus_tag="VU722_000547"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU1771580.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSRDKLNRLFDLETDFTFESSEQAWSALLWALEIENAQSFLKFWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            68007..69878
                     /locus_tag="VU722_000548"
     CDS             68007..69878
                     /locus_tag="VU722_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1771581.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHNLKKELSGGVAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKTFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIEALEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(70021..71205)
                     /gene="mntE"
                     /locus_tag="VU722_000549"
     CDS             complement(70021..71205)
                     /gene="mntE"
                     /locus_tag="VU722_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU1771582.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            71509..74205
                     /locus_tag="VU722_000550"
     CDS             71509..74205
                     /locus_tag="VU722_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU1771583.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVLLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKARDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHILTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            74218..75009
                     /gene="yghU"
                     /locus_tag="VU722_000551"
                     /pseudo
     CDS             74218..75009
                     /gene="yghU"
                     /locus_tag="VU722_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
     gene            75125..75535
                     /locus_tag="VU722_000552"
     CDS             75125..75535
                     /locus_tag="VU722_000552"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU1771584.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKCYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            75547..77142
                     /locus_tag="VU722_000553"
     CDS             75547..77142
                     /locus_tag="VU722_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771585.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            77208..77372
                     /locus_tag="VU722_000554"
     CDS             77208..77372
                     /locus_tag="VU722_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU1771586.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            77451..78179
                     /gene="yaaA"
                     /locus_tag="VU722_000555"
     CDS             77451..78179
                     /gene="yaaA"
                     /locus_tag="VU722_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU1771587.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVVGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(78546..79094)
                     /locus_tag="VU722_000556"
     CDS             complement(78546..79094)
                     /locus_tag="VU722_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1771588.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQVVGDFTAARVNDSAWADGKL
                     VLEETVLNSLDKQAQDLVNAIK"
     gene            79415..79903
                     /locus_tag="VU722_000557"
     CDS             79415..79903
                     /locus_tag="VU722_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU1771589.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            79900..81087
                     /locus_tag="VU722_000558"
     CDS             79900..81087
                     /locus_tag="VU722_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1771590.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     ENN"
     gene            81080..81445
                     /locus_tag="VU722_000559"
     CDS             81080..81445
                     /locus_tag="VU722_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1771591.1"
                     /translation="MIDHFEIKVKDLQILEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            81461..82807
                     /gene="asnS"
                     /locus_tag="VU722_000560"
     CDS             81461..82807
                     /gene="asnS"
                     /locus_tag="VU722_000560"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU1771592.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            82960..83250
                     /locus_tag="VU722_000561"
     CDS             82960..83250
                     /locus_tag="VU722_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU1771593.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIKDFREGLYHIVNVEANDDVALKEFDRLSKINADILRHMIVKIDA"
     gene            83262..83732
                     /gene="ssbA"
                     /locus_tag="VU722_000562"
     CDS             83262..83732
                     /gene="ssbA"
                     /locus_tag="VU722_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU1771594.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTVGAYSAPTANYSAPTNSVPDFSRDENPFGATNPLDISDDDLPF"
     gene            83764..84003
                     /locus_tag="VU722_000563"
     CDS             83764..84003
                     /locus_tag="VU722_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU1771595.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
BASE COUNT        26140 a        15083 c        19100 g        23687 t
ORIGIN      
        1 cacaaaagag ggaaaagaca gatttggtgt ttcgtagaag taaaaacagc ccaaagaggg
       61 ctgtcagtta agatgagatt tcaacttaaa tcgcaaacaa gtcattcaag ttctcagcca
      121 aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg ttgtccatag
      181 caacagtaat gatgttgatg atttcttgag aaccttctga gaagatgctt gcaccaagaa
      241 tttcttttgt ttcagtatta acaacagctt tgaaagctcc gcgaaggtct ccatttacgt
      301 gaccacgagg catggctgca acagggattt ctttcactgc gtatggaagt ttcaaatcag
      361 ctgcttggct ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac atagtatttg
      421 gcacattgag acggtcctca agtgtgtagc tgccatctcc agcaaggtag ctataaacaa
      481 cacggaagtc atcaagtgaa atgtaagtaa attgaagacc accgttgaca tctccaactg
      541 caaagacacc aggaacgttt gtttgacagt gtttatctac tttaatagcg ccacgttcag
      601 ttagttcaat atctgtattt tcaagttgaa gtggttctac atttggtttg cgtccagttg
      661 cgtagagaag ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc acttggtcac
      721 cgtcgttttt aatttcagta gtatggatat tttgaagcaa ttcaataccg tcttcttcca
      781 ggtattgttt agcaagagct gcgatggaag gttctgcacg aggtaggaat gtatccaagg
      841 catctaggac tgtaaccttg cttcctagtt tattgtaaag gccagcaaat tcaagaccga
      901 tatttccgcc accaaggact ccaagttttt caggcaattt atccaagctt tggatacctg
      961 ttgagtcaaa gacgtttttg cttgtagcaa gtccagggat tggcaagacg tttgaaacag
     1021 caccagtgtt gatgacgata gtttcagcag tcaattcttg tttttcatca ccagcttgga
     1081 tttcgatgac tttatttgaa aggaagtgag cttcagcatc aaagatattg acgccagtac
     1141 cagcaacagt cgtatagttt ttaccgttga ggcgaccagt gatcgtgttt ttggtagcaa
     1201 tgacttcttc aaaagacaag tctttctcag cagcaaccag caaagtttta gttgggatac
     1261 aaccgatgtt gatacaagtt ccaccgtaca tagctttgct acgttcaacg agggcaactt
     1321 ttttgccagc tgaagccaat ttaccagcta gtgttttacc agctttacca aatccgataa
     1381 cgattaaatc ataagttaac atttagaatt cctcctattc gaattacatt ctagcacaag
     1441 aaaaaaactt ttgcacaatt ctgctacgaa aaagacagaa aaagataaaa acgctttcca
     1501 gacaaaaaac tagtaatttt ttaacaagct tgataaacta aaatcctatc tatttttata
     1561 taagaaagaa taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg
     1621 cctttgctgg ggtcatttta cacttaatgc tgggttcgac ttatgcctgg agtgtttatc
     1681 gtaaccctat tattgaaaaa acgggatggg atcaggcttc tgttgccttt gcctttagtc
     1741 tagcaatctt ttgtttgggc ttatcggctg catttatggg gcgtttggta gaaaaatttg
     1801 gtccaaaagt catgggaagt ctatctgctt ttctatacgc aggtggaaat atcttaacag
     1861 gatttgcaat agaccgtcag gagctgtggt tgttgtatct cgcttatggc attttaggtg
     1921 ggcttggttt gggagcaggc tatattaccc ctgtgtcgac gattataaaa tggtttcctg
     1981 ataaacgtgg tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga
     2041 ctagtcccat agcgcaacac ctcatcgcag gggtagggct tgtagaaact ttttatattt
     2101 taggagcaag ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg
     2161 agcaagagct tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag
     2221 gaatggctgc aaatcaggct ctaaaaagca atcggtttta tatgctttgg attattttct
     2281 ttatcaacat agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga
     2341 tggctggctt gtctacaagt catgcagcag taatggtggg tgttttgggg attttcaatg
     2401 gatttggtcg cttgctctgg gcgagtttgt ctgattatat cggtcgccct ctaaccttta
     2461 gtatattact gcttgtcaat cttttctttt ctctctcact ttggctcttt acagattccg
     2521 ttttatttgt agttgctatg tctattttga tgacttgcta tggagctggt ttttctttga
     2581 ttccagctta tctcagtgat atttttggaa ccaaggaatt ggccgctcta catggttata
     2641 ttttaacagc ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata
     2701 aaatggctca ttcgtacaca caaaccttgt tcgtttttct cattttatac agtattgcct
     2761 tggctttgtc ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat
     2821 gattttctgt agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg
     2881 caaagaaaac agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat
     2941 atgaaaatac gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca
     3001 cctttagaaa gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctgg
     3061 cagaaattga aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt
     3121 tggcccttga aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag
     3181 cctttggctt gcctaccctt gaaaaaatcc gtacagaaga agcgactatc caagccttgg
     3241 tcatcgctcc aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc
     3301 gtagtaaggg agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta
     3361 aggctcttaa atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggatttga
     3421 ttaaacgcaa ggccttgaaa ttacaaaaca ttgaaaccct tatccttgac gaagcggatg
     3481 aaatgcttaa catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga
     3541 accgtcaaac tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc
     3601 agtttatgaa agcccctgaa catgtcaaga ttgcggctaa ggaattgaca acagaattgg
     3661 ttgaccagta ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca
     3721 tggatgtggc acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg
     3781 aattgactcg tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag
     3841 accaaaacaa acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg
     3901 ttgcgacaga cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact
     3961 acgatattcc acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg
     4021 gtaagtcagg tcaatctatt acttttgttt ctccaaacga aatgggttac cttcaaatca
     4081 ttgaaaactt gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct
     4141 tccaatcaaa aaaacaggta gctctcaaga aaatcgaacg tgattttgta gatgaaacca
     4201 ttcgtgccaa ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc
     4261 cagaagaatt ggcaatgtat atcttgagtc tgacagtcca agatccagat agccttccag
     4321 aagtggagat tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg
     4381 gtaaagctaa gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgcc
     4441 gtggcaatgg tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata
     4501 aggaaaaacg ttactgtaag gataataaaa aaccacgcaa tactttaagc gaaaagcaaa
     4561 caggctttgt tattcgtaac aagggcgata aataagaaaa agcggttcaa aatgaatcgc
     4621 ttttttatat aaggagaccg aatgtgaaaa agacaaataa atttattata ttatattgta
     4681 taatattatg atatgtaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaac
     4741 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     4801 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     4861 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     4921 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     4981 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     5041 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagata actacgttca
     5101 aggggctaat atgatttacg aaacagaagc aaacttgcct gttgagcatg atatgagtat
     5161 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     5221 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     5281 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     5341 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     5401 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     5461 tgaaggacag ttgactgcgt cagtgattgc agatcgtatc ggaattactc gctctgtgat
     5521 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     5581 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     5641 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     5701 gggaagctga cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     5761 cgattagctt ttgaacgagg agattatatc ttctttacca ttgatgctca tgaagaaaac
     5821 gattgtttcc atccagaaag taaactattt cctcctcata atttgattgg gactggtgga
     5881 cgaaatttat acggagattt ggggatcttt tatcaagaac atgattcaga cagtcgtgtc
     5941 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
     6001 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
     6061 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
     6121 gcttccattt ggcctgaaaa tcatcaattt tccctaggtc atttcaaaaa tacactcgga
     6181 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aatctggttg gcgaaaatga
     6241 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
     6301 gacgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
     6361 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
     6421 tgtatttctc taaaaaatta gcatccagtc aaatgtagtg gagaatcatc gaaaatatga
     6481 gaaaactgat ccttgtttct gcttttgtca tagaagaata atcaagatta tcttcttcaa
     6541 attctccgat attctctaaa gttttgtgca agttgcacag aacttgttta tttttttggt
     6601 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
     6661 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
     6721 aacactactc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
     6781 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
     6841 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
     6901 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
     6961 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
     7021 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
     7081 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
     7141 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
     7201 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
     7261 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
     7321 gtacaggtac tatcggacgt gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc
     7381 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaccgtga
     7441 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
     7501 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
     7561 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
     7621 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
     7681 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
     7741 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
     7801 aaaataaata aaattcaaag cactacaaga aaagatatct ctttatcaat tgtagtggag
     7861 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
     7921 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
     7981 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
     8041 agctgtactt tgagcagctt acggctagtt tcctagtttg ctctttgatt tccattgagt
     8101 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
     8161 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
     8221 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
     8281 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
     8341 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
     8401 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
     8461 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
     8521 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaattagtt ttgaaagagc
     8581 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
     8641 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
     8701 aaaacctgga ggtcttctct tgacacatga tgtgcttctt aaggaagcta aagagtctat
     8761 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatgcttg
     8821 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
     8881 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
     8941 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
     9001 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
     9061 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
     9121 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
     9181 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
     9241 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
     9301 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
     9361 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
     9421 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
     9481 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
     9541 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
     9601 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
     9661 tgaaaacagt ccttagggct gttttctcta cactaggata taaaaataga ctataactag
     9721 ttagagaaaa actataattg aaaactatat cttcttgcag tataataaaa ggactaagtg
     9781 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
     9841 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
     9901 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
     9961 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    10021 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    10081 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    10141 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    10201 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    10261 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    10321 ggacagtaag ctatcaggta tttatcctca gaacacccta aaagagggtc accttctatt
    10381 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    10441 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    10501 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    10561 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    10621 agaaaattac tttaaagatg aggatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    10681 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    10741 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    10801 tatttagacg cttttaaatc aggtaccttg gttttaccga gtgccctgct cttgcatttt
    10861 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    10921 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    10981 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    11041 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    11101 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    11161 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    11221 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    11281 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    11341 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    11401 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcagaaatgc catggatctc
    11461 tggaaggatt aatccatgca agcaggcttg aaatccgagt aagatttgca agctgtgtat
    11521 aattgtgata gaataaaata gaaaataaat tgaaaaaaga ggtatgtgaa atgtcacgta
    11581 aaccatttat cgctggtaac tggaaaatga acaaaaatcc agaagaagct aaagcattcg
    11641 ttgaagcagt tgcatcaaaa cttccttcat cagatcttgt tgaagcaggt atcgcttctc
    11701 cagctcttga tttgacaact gttcttgctg ttgcaaaagg ctcaaacctt aaagttgctg
    11761 ctcaaaactg ctactttgaa aatgcaggtg ctttcactgg tgaaactagc ccacaagttt
    11821 tgaaagaaat cggtactgac tacgttgtta tcggtcactc agaacgccgt gactacttcc
    11881 atgaaactga tgaagatatc aacaaaaaag caaaagcaat ctttgcgaac ggtatgcttc
    11941 caatcatctg ttgtggtgaa tcacttgaaa cttacgaagc tggtaaagct gctgaattcg
    12001 taggtgctca agtatctgct gcattggctg gattgagtgc tgaacaagtt gctgcctcag
    12061 ttatcgctta tgagccaatc tgggctatcg gtactggtaa atcagcttca caagacgatg
    12121 cacaaaaaat gtgtaaagtt gttcgtgacg ttgtagctgc tgactttggt caagaagtcg
    12181 cagacaaagt tcgtgttcaa tacggtggtt ctgttaaacc tgaaaatgtt gcttcataca
    12241 tggcttgccc agacgttgac ggtgcccttg taggtggtgc gtcacttgaa gctgaaagct
    12301 tcttggcttt gcttgacttt gtaaaataat cagtaagtag caaaagctag gtggaacagc
    12361 attcagatgt ctgttacatt ttttatagga gagaaagatt gaaaacaaaa attggattag
    12421 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    12481 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    12541 ataaaacgca aacgagcgca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    12601 attatgtaaa ggatgatggt tctaaagctc aaagtgaatg gatttttgac aactactata
    12661 aggcttggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    12721 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    12781 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    12841 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    12901 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    12961 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    13021 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    13081 gcaactacta tttgactgga agtggtgcca tggcgactga cgaagtgatt atggatggta
    13141 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa aaaagatttg aatgtcggct
    13201 gggttcacag agatggtaag cgctatttct ttaataatag agaagaacaa gtgggaaccg
    13261 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    13321 aggttattga tgagaacgaa gtggatggtg tcattgttcg tctaggttat agcggtaaag
    13381 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    13441 tctatctcta tacctatgct gaaaatgaga ccgatgctga gagtgacgct aaacagacca
    13501 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    13561 attgggaata tgtaaataag agcaagagag ctccaagtga tacaggcact tgggttaaaa
    13621 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    13681 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    13741 gggtagcggc ctatacgaat gctttagaat gggaaaaccc tcattattca ggaaaaaaag
    13801 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    13861 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    13921 tttatgatag ttcatcctcg agtaaattca agttcttgct cggaaatgaa gcttatatag
    13981 tagattgaat atagacaaat accttgtgat tggtaaaaca ttttagaaat tcatttacct
    14041 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    14101 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    14161 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    14221 tgtcttctaa agaattctta aattatcagt ctattgcaac ttttctcata taagttcttt
    14281 gtcttgctat tggttttcct tagtagtata ctaaggtagt aatcattaag aagtggttac
    14341 aaaaaataat gaatgaggta aagaaaatgg tagaattgaa aaaagaagca gtaaaagacg
    14401 taacatcatt gacaaaagca gcgccagtag cattggcaaa aacaaaggaa gtcttgaacc
    14461 aagctgttgc tgatttgtat gtagctcacg ttgctttgca ccaagtgcac tggtatatgc
    14521 atggtcgtgg tttccttgta tggcatccaa aaatggatga gtacatggaa gctcttgacg
    14581 gtcaattgga tgaaatcagt gaacgcttga ttacactcgg tggaagccca ttctctacat
    14641 tgacagagtt ccttcaaaat agtgaaatcg aagaagaagc tggtgaatac cgtaatgttg
    14701 aagaaagctt ggaacgtgtt cttgttatct accgttactt gtcagaactt ttccaaaaag
    14761 gtttggatgt cactgatgaa gaaggtgacg atgtgacaaa cggtatcttt gcaggcgcta
    14821 aaactgaaac agataaaaca atttggatgc ttgcagccga acttggacaa gcacctggtt
    14881 tgtaagaaat aaggaaacat agataaatct gtaggaaatt tcttacagat tttttctatt
    14941 ttgtaagcta ttccaaacca gtcttttttt gagttttttg ataaaatagt actatcagtg
    15001 aaaaggatgg aagcatgact aagaaaatcg tagctatttg ggcccaggat gaagagggtg
    15061 tgattggtaa ggaaaatcgt ctgccttggc atttgccagc agaattgcag cactttaaag
    15121 aaacaactct gaatcatgct atcttgatgg ggcgtgtgac ctttgatggg atggggcgtc
    15181 gcttgcttcc aaaacgggaa accttgattt tgacgcgtaa tccggaagaa aagatagatg
    15241 gggttgctac ttttcaggac gtccagtctg ttcttgactg gtatcaggct caagaaaaga
    15301 atctctacat tctcggtggg aagcaaattt ttcaggcttt tgaaccttac cttgatgaag
    15361 tgattgtcac tcacattcat gctcgggtgg aaggagatac ctatttccct gaagagcttg
    15421 acttgtctct ttttgagaca gtttcaagca aattttacgc caaagatgag aagaatcctt
    15481 atgattttac catccaatac cgcaagagaa aggaagtcta atggaacgga gtttatttgg
    15541 tctattcacg gcttttctgt gtttcatctg ctttctggca ggagcacagg cttttcgtaa
    15601 aaagcgttac gggctttcta tcctcctttg gttaaatgcc tttaccaatc tggtcaatag
    15661 tattcatgct ttttacatga ccttatttta gatagaatga cagtatagaa tggaaggaaa
    15721 tcatgtctac aaatagaaaa aatgatatga tggtttattg ctcattttgt ggcaaaaacc
    15781 aagaagaagt acaaaaaata attgctggca acaatgcttt tatttgtaat gaatgcgtgg
    15841 agttagctca ggaaatcatt cgagaagaat tggttgagga agtcttggca gacttatctg
    15901 aggtgccaaa accaattgaa ctcctccata tcttgaacca ctatgtaatt ggtcaagatc
    15961 gtgccaagcg tgccttggca gtggcggttt ataaccacta caaacgcatc aatttccacg
    16021 atacacgcga agagtcagaa gatgtggatt tgcagaagtc aaacattttg atgattggcc
    16081 caactggttc agggaaaact ttccttgccc agaccttggc taagagcttg aatgtacctt
    16141 ttgctattgc ggatgcgaca gctctgacgg aggctggtta tgtgggtgag gatgtggaaa
    16201 atatactcct caaactcttg caggttgctg actttaacat cgaacgtgca gagcgtggca
    16261 ttatctatgt ggatgaaatt gacaagattg ccaagaagag tgagaatgtg tctatcacac
    16321 gtgatgtttc tggtgaaggg gtgcaacaag cccttctcaa gattatcgag ggaactgttg
    16381 ctagcgtacc gcctcaaggt ggacgcaaac atccacaaca agagatgatt caagtggata
    16441 caaaaaatat cctcttcatc gtgggtggtg cttttgatgg tattgaagaa attgtcaaac
    16501 aacgtctggg tgaaaaagtc atcggatttg gtcaaaacaa taaggcgatt gacgaaaaca
    16561 gctcatacat gcaagaaatc atcgctgaag acattcaaaa atttggtatt atccctgagt
    16621 taattggacg cttgcctgtt tttgcggctc ttgagcaatt gaccgttgat gacttggttc
    16681 gcatcttgaa agagccaaga aatgccttgg tgaaacaata ccaaaccttg ctttcttatg
    16741 atgatgttga gttggaattt gacgacgaag cccttcaaga gattgctaat aaagcaatcg
    16801 aacggaagac aggggcgcgt ggacttcgct ccatcatcga agaaaccatg ctagatgtta
    16861 tgtttgaggt gccgagtcag gaaaatgtga aattggttcg catcactaaa gaaactgtcg
    16921 atggaacgga taaaccgatc ctagaaacag cctagaggtg actatggaac tgaatacaca
    16981 caatgctgaa atcttgctca gtgcagctaa taagtcccac tatccgcagg atgaactgcc
    17041 agagattgcc ctagcagggc gttcaaatgt tggtaaatcc agctttatca acactatgtt
    17101 gaaccgtaag aatctcgctc gtacatcagg aaaacctggt aaaacccagc tcctgaactt
    17161 ttttaacatt gatgacaaga tgcgctttgt ggatgtgcct ggttatggct atgctcgtgt
    17221 ttctaaaaag gaacgtgaaa agtgggggtg catgattgag gagtacttaa cgactcggga
    17281 aaatctccgt gcggttgtca gtctagttga ccttcgtcat gacccgtcag cagatgatgt
    17341 gcagatgtac gaatttctca agtattatga gattccagtc atcattgtgg cgaccaaggc
    17401 ggacaagatt cctcgtggta aatggaacaa gcatgaatca gcaatcaaaa agaaattaaa
    17461 ctttgaccca agtgacgatt tcatcctctt ttcatctgtc agcaaggcag ggatggatga
    17521 ggcttgggat gcaatcttag aaaaattgtg aggaaaagaa aatggcaaaa acaattcata
    17581 cagataaggc cccaaaggct atcgggccct atgttcaagg aaaaatcgtt ggcaaccttt
    17641 tgtttgctag cggtcaagtt cccctatccc ctgaaactgg ggaaattgta ggagagaata
    17701 tccaagaaca gacagagcaa gtcttgaaaa acatcggtgc tattttggca gaagcaggaa
    17761 cagactttga ccatgttgtc aaaacaactt gcttcttgag cgatatgaat gactttgttc
    17821 cttttaatga ggtttaccaa acggccttca aagaggaatt cccagctcgt tcagctgtgg
    17881 aggtagctcg tcttcctcgt gatgtaaaag tcgaaattga agtcatcgca gagattggat
    17941 aagctagttg aagtttggtg ttgccaaact tcttttgata taaggagaaa aagatgacaa
    18001 agaaacaact tcacttggtg attgtgacag ggatgagtgg cgcagggaaa actgtagcca
    18061 ttcagtcctt cgaggatcta ggttatttca ccattgataa tatgccgcca gctctcttgc
    18121 ctaagttttt gcagctggtt gaaattaagg aagacaatcc taagttggcc ttggtagtgg
    18181 atatgcgtag ccgttctttc ttttcagaga ttcaagctgt tttggatgag ttggaaaatc
    18241 aagatggttt ggatttcaaa atcctctttt tggatgcggc tgataaggaa ttggtcgctc
    18301 gttacaagga aaccagacgg agtcacccac tagcagcaga cggtcgtatt ttagatggaa
    18361 tcaagttgga acgtgaactc ttggcacctt tgaaaaatat gagccaaaat gtggtggata
    18421 cgactgaact cactccacgt gagctgcgca aaaaccttgc agagcagttt tcagaccaag
    18481 aacaagccca gtctttccgt atcgaagtca tgtctttcgg atttaagtat ggaatcccga
    18541 ttgatgcgga cttggtcttt gatgtccgtt tcttgccaaa tccctattat ctaccagaac
    18601 tgagaaacca aacgggtgtg gatgaacctg tttatgatta tgtcatgaac tatcctgagt
    18661 cagaagactt ttatcaacat ttattggcct tgattgagcc gattctgcca agttaccaaa
    18721 aggaaggtaa gtccgttttg accattgcca tgggatgtac gggtggacaa caccgtagtg
    18781 tggcatttgc taaacgcttg gtgcaggact tatccaagaa ttggtctgtt aatgaagggc
    18841 atcgcgacaa agaccgcaga aaggaaacgg taaaccgttc atgagaaaac caaagataac
    18901 ggtgattggt ggagggactg gaattcccgt cattctaaaa agtctgcggg aaaaagatgt
    18961 ggaaatcgca gctatcgtga cggtggcaga tgatggtggt tcttcaggtg aactccgaaa
    19021 aaatatgcaa cagttgacac cgccaggtga tcttcgtaat gtccttgtgg ccatgtcgga
    19081 tatgcctaag ttttatgaga aggtctttca gtatcggttc tctgaggatg ccggagcctt
    19141 tgctggccat ccattgggaa atctcatcat tgctggcttg tcagaaatgc agggttcaac
    19201 ctataatgcc atgcagttat tgagcaaatt tttccataca acagggaaaa tttatccttc
    19261 cagtgaccat cctttgaccc ttcatgcagt ctttcaggat gggacagaag tggctggaga
    19321 gagtcatatt gtagaccatc gaggcataat tgacaatgtc tatgtgacca atgccctaaa
    19381 cgatgatacg cctctggcca gccgtcgagt agtgcagatc atccttgaaa gtgacatgat
    19441 tgtcctaggg ccaggttccc tctttacctc tattttgccc aatatcgtga ttaaggaaat
    19501 tgggcgggct cttttggaaa ccaaggcaga aattgcctat gtctgcaata tcatgaccca
    19561 acgtggggag acggaacact ttacagatag cgaccacgtg gaagtcttgc atcgtcacct
    19621 tggtcgccct tttatcgaca ctgtcttggt gaatattgaa aaagtgcctc aggaatacat
    19681 gaattccaac cgttttgatg aatacttggt gcaagtggaa cacgattttg taggtctttg
    19741 taagcaagtt tcgcgcgtga tttcatctaa cttccttcgt ctggaaaatg gcggtgcctt
    19801 ccacgatgga gatttgattg tggacgagtt gatgcgcatt atacaggtga aaaaatgagt
    19861 ttcacagtag caataaaaga agaaatcctg ggccaacacc atctgagctg gcatgaatta
    19921 tctgccatta tcaaaatgtc tggtagcatc ggtctctcga cttcgggctt gactttgtca
    19981 gttgtgacag aaaatgccaa actggcccgt cacctctatg agtcctttct ccatttctat
    20041 gaaatcaaat ctgaaattcg tcaccaccaa cggagcaatc ttcgcaagaa tcgcgtctat
    20101 acagttttta cagatgaaaa ggtgcaggat ttgttaagtg atttgcactt ggcagactct
    20161 ttctttggcc tggaaacagg tattgatgag gcgattttat cggatgagga agcaggtcgt
    20221 gcctatctct gtggcgcttt cttggcaaat gggagcattc gtgaccctga gtcaggcaag
    20281 taccagttgg aaatcagttc cgtttatctg gaccacgcgc aaggaattgc ctcccttctc
    20341 caacagtttt tactggatgc caaggtgctt gagcgcaaga agggggctgt gacctatctc
    20401 cagcgagcag aagacattat ggacttcttg atagtaatcg gagccatgca ggcacgtgat
    20461 gattttgaga gggttaagat tttgcgagaa acccgtaacg acctcaatcg ggctaataat
    20521 gccgagacag ctaatatcgc tcggacagtt tctgccagca tgaagaccat taacaatatc
    20581 agtaaaatca aagatatcat gggcttagaa aatttgccag tagatttgca ggaagtggcg
    20641 caactgcgga ttcagcaccc agactactct atccagcagt tagcagatag cctcagcacc
    20701 cctctgacca aaagtggtgt caatcacaga ctcagaaaaa tcaataagat agcggatgaa
    20761 ttataacgat ataaagcaac cccttgaatt atcaatatct tcaaggggtt ttgttgtgtt
    20821 atgaaatcaa aaaggggcaa ccaaggggca gaattaaaaa atagtatcta atttattgac
    20881 cagtttatcc tccatatctt cagtagtatg agaatagatt tccaaagtca tttttgcatt
    20941 tgagtgccca actcgatcca ttattgattt tattgggagg ccagactctg ctaaaaacga
    21001 aatatgagaa tgcctaaaaa tatggctaga taagtttttt tctattttgg cctgttttcc
    21061 atattttttt aatatctgta tgaagcaagc tattgttgta ggttgattcc atttttcaaa
    21121 acagaaaata taatcatcgc ttgacaatgg ctggaaacgt tcgctaagtc gtactatttg
    21181 tctttgaata gcttctatga cattctctga tactttgatt gtccgtattg aatttgtagt
    21241 ctttggtagc gtcttgattt tgtttactga atcaaaatta cctgtgatct caattttgtt
    21301 gttttcgaag tctatattct tcagttgtaa ggcagttaac tcaccatatc tcataccagt
    21361 taatgtcagc acaagaacca tatcagcgta cttttggtga tattctcgac gattaaggac
    21421 atcgacaagt gcttttattt cttgcatggt gagaaagttg ttacgctttt tttccagttc
    21481 ttctaaagtc tttggttttt gaggaatcgt agtataatcg acctcgttgt tttcaatgta
    21541 agagtattga acagcgtaat taaagatacc tctgagccta tgccgtactt ttttagctgt
    21601 aatatatccg ttgctttcaa taattttttc aatagcctct tgaagaaaac gcctgtcaag
    21661 attagcaagt atggtatcgg atggtatgac ttccttcatc ttcttatcaa ctgatttaca
    21721 attatgtttt gttgattcct ttactgtttg cgcccatgat ttataaaaaa ggttatagat
    21781 ttcttcaaat gtaatgcttt ctacttgttt tgtgctaagt tttttattta tcttctcttg
    21841 caacaagata gcagcttgat ttcttgcctg gggagttttc ttctccatgg tcactgaaac
    21901 tttttttaat ttctcggtat acgggtcttt gtatcgttca aagaatttgt attttccgtt
    21961 gggaagttct tccatccaca ttgcgtttac ctcacttttt tgttaaaatg ggtataagaa
    22021 aaagagcttt ttaatgcttt ttttcttacc actagcctca cgctctcggt ctgcaaactt
    22081 ctgagcgtgg ggcttttttg agttgtttcc aaaatggaaa cagttggttt ttattctaga
    22141 cctgaactaa ctttagaagt caacaagaaa gaaccgtcgt cttgttttga aaacgaaaga
    22201 ataacgctct tgtatttgct accagtagaa gtatatgata ctgtcttact gtcgtggtca
    22261 tttactgaac tagttgttac attgttaggt tctccgtgaa cgctagcaac gtcatcgtag
    22321 ttagttccac cagctccata gttgataata tcaccaactt gaagcgcatc aaactgttct
    22381 tttgtccagt taaatttagc atcttcttct ttttgagatg attcgataga agaacttaca
    22441 gagctaacag tctcttcaac gtttttacct agttctttca atgatttagc gtacattgct
    22501 tgagttacta atacaatagc aatagatacg actgctagaa ccgtcccaat aatagctagt
    22561 gtttttggtc tttttcgatt tactgcaaaa ccaattaaac cgaagataag agctaaaata
    22621 gccaaaatga atgaaaaatt attgatgata ggcatccatg agccaagtag agccagcgct
    22681 ccaaaaataa tagctaaaat acctaaaact ttgcgttctt gtttcataat gaaacctctc
    22741 tatcagcttt tagtgtggat cagttgttgc acatattttt aatttactaa tgataaatac
    22801 tcttctttaa ccatgatttc atttgtcatg gtttttagat tgtagtaaga catgaatttg
    22861 aggtaatcaa actctgtggg gtcgtctaag ctttctagcg cgtcttttac gagatgatgg
    22921 atcatatttc tatcagcttc gttttcacag cgtagtcgag cgttctggta ctctgagagt
    22981 gtatggtctt tgtgtccaag ttcgtgtagg gcgacttgga tttgttgttc aggagtcaag
    23041 ttgtggtcaa tagcgagtac gtttgtgtct ggattgtaga aaccgctact gtgccagttt
    23101 gaaccgtcga agagacaaag ttctacttga tattcttcgc agagtttagc gagtgtcata
    23161 gttctccttt taattagcca ctcgataata acttttaata gctggatagc tttttagttg
    23221 gctttcttga cgtttctttt tttgttcaaa ttgatgaatg gattcattac tgagccgtag
    23281 catgtaatca tattcactgt tattttcttt tggtcgttta acttggacgt gattcatttt
    23341 agattctccg tttttaattc tataattcct ttgtgatttc tatttctatc aaaaccaaat
    23401 tgtcccatcc agtatgtttc attgtgagcc atgtgggaat atataggacg agttttttca
    23461 atatgatctt tatcgcctat ttgatagatg tctaagcagg tacttgcttt ttctttaata
    23521 tcttttagat atttctctat gtctggagaa tgtttaaaaa atagtaagac atctatgtct
    23581 tttgggtttt ctttctgggt gcaaaagctt ccgtctagcc atatacgcgt aatgatattg
    23641 ctatctagat tttttaagaa agttgagaga gcttggaaat ttctagttct ggtagtggag
    23701 tttgggaagt tatctactag agttgattgt atttgtgcta gtgagatatt tgttagtatt
    23761 cctccattta ggttaccttg atcattgaag tggagtttag cgagtgtcat agttctcctt
    23821 tgttatttat aaacctctct gcggtgggcg atgtctacgg ctaagacgac tagtttatcg
    23881 tcttggatat cacagatgat gcgctaatcg ccaactcggt atcggcagta acctgatagg
    23941 tttcctttta gtagtttagc gtgttgatag gggttgcttg tgttgtctac gttttttgtc
    24001 atccacgaga tgatttttcg tctagttgct ccatcgagtt ttttgagttg tttttgtgct
    24061 ttgctttcat agacgagtcg gtacattagg cgatgtcctc tctggtcatt ccaagacttt
    24121 ccaagagttc atctgttgta tatgtttttg gattagggtc ggctaaatac tccatatagg
    24181 cttggtcggc tgctcgtgcg tcttcgatat cttccatgag tgccatgaag tcgtcaaaat
    24241 ccatggtcgt tgtgttgata ccgtgtttgt ttaggtagtc cgtgatgtag gaattttttt
    24301 ctgtgaagtt gatagtgata gtcattagcg ttctcctttg cttttgaagt gggcggatag
    24361 gacggatgtg atgaagtcga tatcatcttc atttagtggt ttcccgtcaa ataacatggt
    24421 gttggctgct gctttgcgta agtctatgat ttgtccgttt acttgggcaa attcatcact
    24481 cccagcaata gcagggttat ctgtacgacc tagaagataa tcagtggaca cattgaagta
    24541 gtcagctatt tctgaaattc gttcagtaga tggttttgaa ctttttaaat tataaatggt
    24601 atttctactg taaccaagtt tttcttccaa tgaatttatt gaaagtcctt gctttttggc
    24661 aagttcttta attctgtcaa atgtctgaaa cattgatttt tcaacctttc tgagaacatg
    24721 acaaaaaata tttaatattt ctcattaaaa cacttgacaa agttaatgcg aagtattaaa
    24781 atagtttttg taagttaatg agttagtaaa aaacgaagtt aaaacttatc taaaaataaa
    24841 tagctttggc gagcaagaaa attgatagat ataaggtttt atcaaggttt ttaattatgc
    24901 tttcatttta atactataca ttaattttgt caagcatttt ataaaacaat ttactaactt
    24961 tttttcttac ttttaaagaa aggagggagg cagatgccaa acatggatgg tggacgtcaa
    25021 aaaatcagag attatctgaa agagcacaac ttgacgatgg cgacgctagc agtacagtat
    25081 agcatggctc gtcaggatgt gacgaatatc ctgaatggaa agctaaaaaa tccacaagcg
    25141 aatcagttca tcgctcgtgt gattgaagat tttaaaattc ggtaaaaata ttggtttaag
    25201 taggaggaaa gatggaagaa gacatcagag ttcacatgcc ttacgaggta tttaaaaacc
    25261 tgcttgttag agcaggcaga ataaagcgtg aagaaggcaa gcagataact tggacaaata
    25321 ataccgctcc gtttacaaaa gagcaacgga gggaaataga tgaactctac gagcagttcg
    25381 cagaagattg aatgtggagt ttgtcattga tatgtttgtt agcaatcaat aaacattcat
    25441 taagcctatc aaaaatatat ctgggttctt cgattgtgtc tgggtcatag gactgttctt
    25501 caaattgcac atcccaaata taaagcccat cggggtgggg atatccagct tgataacgta
    25561 gcacatttct aaaatagatg aatttttttt gctcttcatc gctatctaaa aatagatagg
    25621 tcttataaaa gatatcatcg aagtttgtga tgatatctaa atcaatcgga ggagcatcgt
    25681 caagtcttga ttctacgtat gagacggttt taccactaat cgatgcaaaa ttttgaaaag
    25741 ttgaaatata taaatctcta tcctgactta gttgggtatt taagaaatca accttctttt
    25801 cttcgagttt atttttattt tcaatctttt tttgctggta agcaaaaccg tgaataatca
    25861 aatttgttaa aacagttgca ccaacagaaa tcaatgttgt tgtaaatact tcagacatac
    25921 aaatacctca gataatattt ttaaatcatt atatcacaaa cagaaaggag taggatggaa
    25981 gaatttattg atgctcttga aaaagaaaaa gaccaccttg aaaaaatcat tgaggtagtc
    26041 agctctggtg gtaaatttct gagattgccg tatcaaaaaa gtcacgctcg attagtgaga
    26101 atctgaaatt gatttctcaa aatcttgata gactgagctg tttatataac caaagaggag
    26161 aaagaatgac agacagagaa ctatttaagt taccagaaga ttatgtagaa tctactggac
    26221 ttgacaagat tacatttgaa gtaccttttg aattgtttac gaaaattcta aaagggtacg
    26281 gacataagtt agcgtgggag gatttccgac aaataaaaat ccacccaagc actagaacaa
    26341 aaaagacggt tggacagtgt cagtttttgt ttagtatttg gatgaatgat catttgaagc
    26401 cagcgattaa accttcaaaa gagttgcaga aagaacctgt gcgtaagaca aagaaacaga
    26461 aacgtcttca taagttagca caaaatcttc ttcatcgcat gaagggttga aatcgccaat
    26521 gtatgcacct tgctctgttt tgcagattag aagagtacca tcttcgtttg taactgcatc
    26581 tagataaggt cccaaatcag acttagtcat aagttatcct cctttctgct tatattatag
    26641 cagaaataga ggttagaaat agaaaggagt aggaagatga gaccaaaacg atatccgtat
    26701 agtgggaaaa aagagtccac ctttgtaaag gcagaccctg agttagttga aaaactttta
    26761 agaaacacta gttttcttga gtgtttacaa aaaaagccta tcaattttca gatagactca
    26821 gaagaattta agcgtcttag ctataaagcc attcatgata cttctcaagt aactcaatag
    26881 gaggaaggaa taaaatgatt caccattata taactcacta tgccagcaat gggaaagatt
    26941 acgccgaagc atggattcaa attgattttt tgggaatgtg cttttgtgta tggaaaaagc
    27001 gtacaaccat tgaacgattg tacgcaaacg aagattagac ttttttccaa ccgttgcctt
    27061 tagcagatgt cggagggagc cgatcacctt ttccgatagt tgcggtatga ccattagtaa
    27121 cttttccgcc acgaggtcct acctctacat agcgaccagg tttctgatta tctgttccag
    27181 gttttattgg agtatttgcc atactatctc ctcctttcta ttggaatttt gactaaaacg
    27241 gtgagaggtc ctagtcaaga gtattatagc aatttaggag gatattacat cagtcttgag
    27301 gctgatatag gaggttgaat ggaagataaa attatcgaac ttgctgatta cttcatcagc
    27361 gaatctacaa cgtacagaga agctaaaata gcgtgtgaga agctattgaa acaagtcagc
    27421 catgagatag aactcagggc gatggaaagt aggacagtat gaaagaagca gtaaaggaat
    27481 ttctaaaatt caggagccga tttacaaaaa tagaatggtt tgaaattaac caagctatcg
    27541 aagctcgttt aaatcaaaaa gccgaccagt tgaaactgga cgacttagat ttagaaatca
    27601 tttctagcag actagaaaaa gttatctaga aacgatttga atgaacattg gatggatacg
    27661 atagtcagcg ccacgatagt gaatgtagat ataatcctga tggtacatcg agtttgcttc
    27721 aggtttagaa attggtgagt agagttctgc attttcttcc caccaaatgt aaggattagc
    27781 catatttggt cccattacac aatcgtcgtc ggctgatagg ttcacccaat ttccgcaaag
    27841 acatgcgtga atttcagtca taatattacc tcctttctgg tttcattata gcagaaaagg
    27901 agatagcaaa aaagcacctg acggcaatca ggcgcatgac aaaattattc aagaaaatta
    27961 taacacgaaa ggagcaaaaa tggaagtagt tgaaattgta agaattaaag atgtgatcat
    28021 tgaaaaagtc tctgctaatg atgaagagtt aaaacgtatc tttggatgtt caaaacgaca
    28081 agcaggagag cgaagaagag aaatgcaaaa actccctagt cagcaaaaac atcttttgga
    28141 tagtggacaa cttgtaacga ttaaaggttt ctatgaatac ttgcaatatc gtggaactaa
    28201 agcttggaaa aaagaaatgg aaacaagaaa gaaaatgagg tcagcaggat gaacctacta
    28261 tcaagaatca aaaactattt ttcggaagag gtcaaagaaa ctaatctcga ctggaaagag
    28321 gtcgctttag acctcaatca atcactaatt gaaacacagg aaaaacttca agaagcgaat
    28381 caagaaatcg cagacttgaa gaaaatcgta gcaatctaca aagaaaagga gaaagaaaaa
    28441 tgatggaata catttacctg gtaataatcg taggaattgg actatggtcg ctagtaaata
    28501 aactagatga ccacgctgaa atgaaacaaa aagagcgcca gctgatggca aacaatgtcg
    28561 cacggatgaa tctgagaaat tcagataagc aatttactta tgatgtagaa ccgcctgaag
    28621 ggttgaaata aggaggagaa acatgactca agcggaacaa attagggaat attatagaga
    28681 gcaccctgct gcctcatgtg atgaagtggc tgaggttgtc ggtacaacaa aaagcaacgt
    28741 aagtgcaaac ctggccaaag acatcaaggc aggcagatgc gttcgcttgg aagacaagtc
    28801 atacgactac tccccttact ttaatcacac acaagcgctc actgagttgg ttgattggaa
    28861 gaatgatacc agacgtgagt gggtggatat gctgacaaga gcagcagaaa aagaaacgga
    28921 tagcaatgtt atgcgtttgt taatcaaaga agcaaataaa ttgatgaaag aggtgacgaa
    28981 gtaaatggtt cgaaataaat tgacagattt aacaaatact ttgtttgctc aattggaaac
    29041 cttggacgat agggatctta ctgcagatga attaaagacg gaactccaac gttcaaaaca
    29101 gatggtcgca atctcaggtc aaatcttaca agcaggtcaa ttggcgctag atgctgaaaa
    29161 attcaaagac aaggtaggtg aagtcaatgc cccgatcgct ttgctggaag gatgagtata
    29221 cagagtacat gcatgagata tgccctggcc gattaactcc tgaagtaacc aggttactaa
    29281 atgagaaatt tggtacgacc tataccaaga ctcaaatagg agaagtacgc agacgtttag
    29341 ggttacctgt tggaaaagta tatcaaggta aattgttgac aaaagaacaa catgattacc
    29401 ttgtgtcaat ccaaaaaaat aagatttctc gcgatgtcgc aaatgaaatg aacctaaaat
    29461 ttggattatc actgactgag aaacagatta agagttatcg aagaaataat aatctacata
    29521 gtggtttgac aggaagattc gagaaaggtc agactcctca caataagggg aagaagtacc
    29581 ccaatatgcc aaaaaacagc gggcagttca aaaaaggtaa tcgacctccg aattatgtac
    29641 ctgtcggtac tatcaactac acaacaaacg gttatccaaa agaaaagatt ggagaaccta
    29701 atcaatgggt tttgaaacac cgcaaggttt gggaggacca tcacgggctg ataccaaaag
    29761 ggtactcaat cgtttttctg gacggtgata aaacaaacta tgatatttca aatctggcat
    29821 gtttatctaa gaacgaaatt gctagaatga atcaaaatca tttattcacg tccaacgctg
    29881 atttgactaa aacaggtatt ggactaacaa aacttacaaa taaaatcaga gaggtagaaa
    29941 aaaatggcta gtttatacga actaacaggt cagttcctga caatttacca attggatatc
    30001 gatgacgaaa caaaaacgga cacacttgag gccatcgatt ggcaagaaca atttgaacag
    30061 aaagcagaag gatatgccca tgttatcaag aatctagaag ccgacgtggc catgtacaaa
    30121 gctgaggaag agagcttcaa agccaagaaa caggtggcac agaaaaagct ggattatgta
    30181 aaggataaca ttatggcagc tatgaatatc acggggcaaa ccgaagttaa gagtggtgcc
    30241 ctgattataa aaattgctaa gaatccagaa tcagtcaagg tcaacgaaga cgaccttccg
    30301 aaaaaatatt ttacaaaaaa agtgacgctt gcgccggaca aaaaaacact caaagagttg
    30361 cttaaatctg gcaagaaagt caaaggtgcg aaacttgtcc ggacagaaaa gttggtgatt
    30421 aagtaatgga attgatgaat aaaacacgag taacagattc actagcagtt gtgattggac
    30481 tagaatcgat tgaagtactt gttactgaag gttttctatt tgatgttgcg attcgttttg
    30541 taaaagtaga cgaaacaaat cttgatcaag gaaatgaaaa gccagtattc actccggaat
    30601 gcaagctggt cacagttgct aaatacaagg aaaaacctat ctttgaatcg gaggaagata
    30661 ttcgaaaatt tgagaagcaa gcaaaagaag ttaaatcgct atttgccttt gcaaaggtaa
    30721 ataaacaaaa ttggtttaac actgcccttt atccaggagt gctgactgag aaagttggtg
    30781 tttgatgaaa attttagcta ttgatccaag cagtaataaa attgaaacca gcacaacagg
    30841 agttgtcttg ttggataatg caagattagt tgatagctgg gttgtctctt atggtatgag
    30901 aggtttcgct gattggtttc acgaaatcgg aacaaatctt gaattcgatg tagttattgt
    30961 tgaagaattt aaggcgaggg ataacgacaa gtcgaaagat aatagcgtgg cagaaaccat
    31021 cgcctatatc caactttgct atccaggtgc cattcttcaa ttcaatgcag gttacaagtc
    31081 ggatattcca aacgatcttt tgaaaatctt agacctttgg aaatttgaaa aaagtcatca
    31141 tcaagatatt cgagcagcag caagacttgg attattttgg gcaatgagaa atgatattga
    31201 agaagtggtt catgatatcg gaaaggtggt gagtgagtat cacaataacg ctaagaaagt
    31261 ggcaagctga agcgattaaa agaagtgaac atttatctaa tggaatcttt ttagaggctc
    31321 ttgggggcag aggcaaaact atctgtgcac ttgctattgc aaaacataaa aaagctaaaa
    31381 aaatcatcat cacaaacaat cgactagcta ttctgaatgg ttggatagat gcagtcaagt
    31441 ttatgaattt tgataaaggt gttgagatta tcattcagac agatagatat cttcaaaatc
    31501 aagtcaaaaa ggggcataaa ttagattgtg atgtgctgat agtagacgaa tggcagaata
    31561 tgtcttctga caaacaagtg gccttatatc gcaaaataaa gcgaaaatac acgataggtc
    31621 tttcagcgac accaattcgg aaaaaaggac aaaatttcta tccgcttgaa aaaacggtat
    31681 ttggttgggc aaccccaaat aataaatttg actggcaaaa gactcatggg aaaatggtct
    31741 atgatccatt tagctattca aaagagaagt gggaagattt tcaaaattat gaaagttata
    31801 tctcgagctt gcctaatttc ttccgctggg aagagattga aggaattgag aatgcagttg
    31861 agaataacgg ttttgagatt aagttttacc gaaagagagt cgcctctggc aatccagaaa
    31921 aacttgcaga atttagaaaa ctaaatcttg taacagtgga cggcaaaact gcaatggcca
    31981 agcaatcgtt tggaagaaag acctttgaac gctaccttaa tcaaacaggc gtagcagtcg
    32041 attttccaaa attaaagcca gtaaatgcgg atacgccatt gatgttacaa cttgacggtt
    32101 taatcgaacg agcaccacac gatatgttga ttgtcagtaa atctaagcag attgtcaacg
    32161 tcattagcga gcgccatcct gaaattggaa tctggacggg cgatattcaa gaaggacttt
    32221 ataagaaatc cgtggttgct actagtcaag tgttaggtgt cggagtagac ggcttgcaac
    32281 acaaatacca aactattgtc gtattggatc cagtagaaga aggttctgga gaatatgatg
    32341 attatcgaca attgctctgg cgcataacag gaagtcgtca gcagcatgat gtaaatgtaa
    32401 ttgaatttta ttataaagaa agttaaaaaa agaggaaaac aaaatgaata aaacaactga
    32461 aatgatcgta tttcgtagcc gtaaaactgg agaatttctt aattcttaca aggacagaag
    32521 ttctttagca tttgcagctg acttttgcag cttggaatat tgtttgaagc ttcctcgtaa
    32581 aaaatacgaa gacaacaaaa agacttacaa ggctcttgct gcagcttttg actgtgaaat
    32641 tgtcgcagtt gaagcggaat acaaattgac ctatccgaat ggatcagaag ttgaacctat
    32701 caagcgtgac cgttcatcaa ttgaggacat gattaaggat attattggag gggttctcta
    32761 atggcattta cacttccagc aaataaacca caagttccta aagatacccc agaaattttt
    32821 tcatctacgg cgaaaccatg agcggaaagt cttatcttgc aaatgaattc ccaaatccaa
    32881 tcgttttgaa cacagacggg aatgcagaag ctaacactgt tccaagcatt cagctgatca
    32941 atgaaaaaga tgacaaggga cgaattacca attcagtaat taagcagctt ggagatatct
    33001 tgcttgctct ccagacacag aagcactctt atgaaacagt cgttattgat gtaattgacg
    33061 atgttattga aatgattaag attgcagttt gtgatgaatt aaccccagtt ggtaaacctc
    33121 gcttgaaatc cttgtcggaa attccatacg gcaaaggata cgacttcttt aaccaagcta
    33181 tcacagaatt agtcattgac ctcaaagcat tgccaatgaa tgttatttac atcagccgtc
    33241 aggtatctga atatgatgac aatggcaatg ccaccaaaga caagccaagc ttgaaagata
    33301 agtatgtcaa tcttatcaat ggaaactctg atttgatgat ccacactgaa aaactcggca
    33361 acaactacaa ccgtgaggtt gaccgcaagc gtaagaccta ttatgcggac caggttgatg
    33421 acaaggccat cttgaaaatc ttggcaacta tccgtggggc tgttgagcct gcaaagggca
    33481 agctagctcc taaaaaagaa gcagctaaga caactaaacc agctaagatc gaaaaaacaa
    33541 aagaggcacc taagaaagaa gttgactctg atgatgaact attttaagaa ataaaggaga
    33601 atacacatga gcttactaga tatcgcaaaa tcaatcaaaa aagagggctt tgacccacgc
    33661 aaagacagcg ccaacggtcc tgcaccaatc ccagctggta cttatccagt agtcctgaag
    33721 aaagcaacct tcaacgtatc ggacaaaggc tgggaaagcc ttggttatca atttgaaatc
    33781 cgtggcggtg attacagtgg acgctctgaa tttgcaacat ttggcacact gactgaatgg
    33841 aacggtaaga accttgactg ggcagttgaa cgcactatga aattctttat caaagccttg
    33901 gtccttgctg gcgacagtat gcaaggaaat gaagaagacg gtaaagcctt ggaagaggct
    33961 ctacaacgta aggcagttgg ctcttactac aaccttgtta tctctgtgac taaggggaaa
    34021 gatggccgtg agttccgaaa ctatgacctt gaagaagaag aagcacaacc gctgactgaa
    34081 gctgatatcg atgaagatga cctccctttc taaaaaatag caagttttgg gtcattgatg
    34141 aaactgatga aagattagga ccattcaata catttgaaga ggcttatcaa tcgttgttat
    34201 tttatttaaa aatgactgaa gatgaatatc agtcaaacta tacggcccag gaacttgttt
    34261 atatttacaa agaggagaaa aaaccatgcc gtcgatgaaa gaatacgcat tacagtacca
    34321 aaagttaggg ttctcagtca ttccaatcaa tcctaaaaac aagatgcctt taatcgaatt
    34381 tgctgataaa ccagccatga ctgcaagtga aatcgaacga ttttgggatg gatacccaaa
    34441 tgcgaatatt gctttaagga caactaactt ctttgtcatt gatatcgata agcatggcaa
    34501 agagaatggc tttgagtcgt taaaaaaatg ggaacattta aatttaattg aaccaactct
    34561 tcaagccaaa actgctagtg gtggaaagca tctgttatat ttcaaaagag atgatgaacc
    34621 aattactcag atgattaaat tcttgcctgg tgttgatatc aaagcgcacg agaataacta
    34681 tatcatagta gcaccttcag caacagagaa tggccagtat gagtgggatt tggagaaatc
    34741 agcggaaggt gggacaatcg taactccttc ccgtgatcta atccgagcaa ttaagaagca
    34801 gtatggtaaa actcatggct atagatacga tggcaaagat ggtcttaggg atttagcgag
    34861 gcgttcacaa accagagacc gaacacagac tacagatctc tttgaaacca tcgcccttgg
    34921 ttttggtgat gaaggtggac gaaatgacaa actagcaaaa ttcgtaggtg gtctcttata
    34981 tcgtgcggtc gacgatggtg tagttgttca acttgcaaga ttagcaaatg caaatagtcc
    35041 aaaccctttg cctgaaaagg aaatgatgcg tactattgaa agtatgatta aaaaagatag
    35101 gaggtgattg tgattggtaa tgtagtaagt attgactcac aacctaagat gataacgact
    35161 gccaagggag acatcaaggc caacagtcca agtaatgtgt tgatgtcttt caaagctgat
    35221 gatcagttga gtatttacct aaagcacaac gatttttccc aagagcatga actccttaaa
    35281 gatatcaaga tcggcaacac tctttttaaa aaaggtgagc tcccttctaa ctttgattca
    35341 gtcgtaaaag tttactttga aagtgtgtta ggtgttgctt tctcaaacca agcgatgctt
    35401 gatggcatgg agactttctt ttcagaaaga tcatacaatc cagttattga gtatatggag
    35461 agagcaactg aaaagtggga cggcagaaac cggattgacc gcatgcttca agtatatctc
    35521 ggcgctgaag atatcccttt agtttctaaa atcgctcaaa tgtggctagt tggtgcagtt
    35581 gctaaagttt atgatccata cgttaagttt gactatgttc tggacctggt cggtggacaa
    35641 ggagttggga aaacgtccct ccttcaaaaa ttgggtggcg aatggtatac ggatgccgta
    35701 acagatttct ctaataaaga taattacgac attatgttaa agagtctaat cgtcaacgat
    35761 gatgaaatgg tggccagtaa tcggatgagc tttgcagaaa ctaaggcctt tatttctaaa
    35821 actagcctac gttatcgtaa accatacatg aaacgaacag aagaatttgc caagaacttc
    35881 atcttagcca ggactactaa tcaaaaagaa tacctcaagg acaaaaccgg tgaacgtcgt
    35941 tttctaccag ttatggcaga tagtaaacgg caaaaaaaac atccaatgga aatcgagcca
    36001 gagacaattg aacaaatctg gggcgaagcc gttacaatct atcgtgctgg tgctgatttg
    36061 atgtttgatg aaaatacaga ggatgaactg aatatctacc gtgaacagtt catgtatcgt
    36121 gatgaagttg aattacaagt gcttgaatat cttgatatgc ccgtccctga aaattggcaa
    36181 aactggtcta ttcagcaaca acatcaatac acaagtaaat atttcgataa tagtagcgac
    36241 tttgatcctg gaagcaaaaa actagataag gtctcaactc gtgaaatgat gtacaactta
    36301 tttatgagaa attcgaatga caggaagctg tcaacgaaga ttaacatgat catggataat
    36361 catcctgatt ggaaaaaaag tgttttccgg gcaggaggta aaagtacaaa agggttcgta
    36421 agagtgaaag attcggaaaa aaactaatcg gtagcaatta aaaaattatc ggtagtcatc
    36481 ggtagcagtt gagggggaga tcggtagcat tctaccgata aaataggaca tcggtagcac
    36541 atcggtagca gtctaacccc ttgatattac tgacttttat ttaatattta tatataatgc
    36601 tactcttcta tctatatttt taaaaaaagt atataaaata atagtaataa taaagaaagc
    36661 ctataaaata gggattcttg aaaaaaactt tttacttttt agaatttatc ggtagcacgg
    36721 tagcagttta gaaaaaagag gtaaaaatgt catacacagt aacattattt tttgacaaca
    36781 tggtagacga aactcacttt tttaagaaag agagtgatgc tgccaaatgc aaggcgcagt
    36841 tagaaagcaa gtatcgaggg aatcgaatgt ataaagttaa gcaggagaaa ttggaagaat
    36901 gaataagcag gaattgattg agaaatataa agagctggag aatagttcat ttgatattgc
    36961 agcgattgta gtttgtcagc taattttaaa agacttggaa cagctagatg aaccaaaacc
    37021 ggtcaaagtt cagcagtttg tggcggattt tatcgcagaa cagaaaaaac tgggtcatac
    37081 actgtcctac tcaatagacg caagcatgtc tgatatagtt gcagaatggt attgggataa
    37141 ttccgaactc ttcgcactag cttggatttt cggctacgag gtcgaggaag agaagcggta
    37201 tacagtagtg acgaaagcaa caaaacaacc gctatattat aatgctatgg ataagaaact
    37261 attcttctct atgggcggac tagctacaaa atttactcgc aaacaactca aagaagcgga
    37321 cttaggctgg gttttcgatt gtgaaggaat tgagattgag gaggtggagt gatggaagat
    37381 gagcaaaata ttttagagac acaattgatt ttaggtaagc aagttttaga aattgtattg
    37441 gatttgctaa aagacgattc aaaaataggg gtagttctac ctttaaacat aaatgaccgt
    37501 gaatttacaa ttactgtaga aaaggaggtc acagatcgtg actaaggggt gtttgtggtt
    37561 atgaaggacg tgtatgacaa ggtgaaagtc ggggatgagg tgatgttgtg aaattcttga
    37621 atttattcgc aggaattggc ggttttcgtt taggaatgga gtctgccggg catgaatgta
    37681 taggattttg tgaaatagac aaattcgcta gagctagtta taaagctata cacgatacga
    37741 aaggagaaat tgaattacat gacatcacaa cagtatcaga tgacactatt cgaggaatcg
    37801 gaagtgtgga cattatctgt ggaggatttc cgtgccaagc tttctcaatt gcaggaaaca
    37861 gacgaggttt tgaagataca cgaggaactt tgttctttga aattgctagg ttcgcatcta
    37921 ttctcagacc taaatatcta ttccttgaga atgttaaagg attgctcaat cacgaaaatg
    37981 gagttacatt cgagaccatt atctcaacct tggatgaact ggggtacaac gtggaatggc
    38041 aagtgcttaa cagcaagaat ttcggagtcc cccaaaatcg ggaacgagtg tttattatcg
    38101 gacatcttag aagagaacgt accagaagaa tttttcctct cagcggaaaa aatcagtcaa
    38161 ctagtaacca atcagtcatg aaaattggga atataaaccc atctggcaac ggaatgaatg
    38221 gggaagtcta tcaagctgat ggtctagctc ccacgctaac aacaaacaag ggagaggggc
    38281 aaaagatagc tataaatagc tatcacgaaa acaatcattt atcagatggc tttcgaatca
    38341 gaaagctaac acctaaagaa tgctggaggt tacaaggttt tcctgattgg acttttgata
    38401 aggcgcagga ggtcaactct aacagtcaat tatataaaca agcaggaaat agcgtgacag
    38461 ttaatgtcat agcagcaata gcaaaggagt tatcatgaac gcactagaaa aagtcgaaca
    38521 atggtttatc gaccgtgaaa tcaaagatcg aaaaggtcgt tggattgatg gtgctttcgt
    38581 caaagaggag gatttggtat gataccgaaa tttagagtgt gggtaaaaat aggaaaacgt
    38641 atggtttttt cagatgacat tcttgctatt gactacgaaa acaaagaaat agtgacacaa
    38701 caagtctatt tcgagagtgg tctagcagtt gaaagagata tctattgtta tgattttgac
    38761 gatatcgaac tcatgcaatc aacaggactt aaggacaaga acgggaaaga ggtctttgtc
    38821 ggagatatta taaaatgtac aagaggatgt ctccatgaag tatatttaga aaaagaatac
    38881 ggtggcacat tcataggcgg aatgccttcc atatatctaa agggattgct aaatgggtat
    38941 gcgtggactg aagacgagga aatcatcgac aatgtctacg aaaaccctga acttttggag
    39001 gtaactcatg aataaacgtc aacgcaaaaa gaaaattttg aacggtctga acaaagaaga
    39061 aagataccac aggacgcatt gtcctgtctg cgatagcgaa gctggtttat tcgacagata
    39121 ttttaatacg tacggtttct gctctgaata ttgtggttat gaatactatg gaatttcaag
    39181 attataaaat aaaggattga ggttaaaatg acattatttg atgaaatgca gcaattaagc
    39241 tcagaaagcc acgcaaaatg gttcgagcga tattttgaga aatataacct agaacaaaaa
    39301 ctaaaaactt ctgctcaaaa aggttataca ggttatttaa tcaatgtttg gtcagttaga
    39361 gacgaatatc tcaggaatcg attaggagat gaaagaacgt tggaagcgtt aagagaatta
    39421 ttaggagctg gctttactgt caaatataag ctttatctat ctaaaaatat tttcactgga
    39481 caagatttcg tttctaacaa gaaaattcac attacttggt aaaacaaaaa agccaagaca
    39541 ctctctgtct cagcaataat ctcaataata ttattatatc acaaaggaga cagagagtga
    39601 acaaggctaa agaactattg aaagagttgc agaatctgga catggacatt caaagccgta
    39661 tagatgaaat taacgagctt gaggcaggtt tgctctcaag tcctaagtgg tcagatgtca
    39721 aagttcaagg tggtcaagct agaaaagttg atgatgtcta tactcagctt gtcgtgatga
    39781 aagaggctat agaacaggat actaaagagg ttatcaacag aaagctccaa ctaggtagga
    39841 tgatcaatag gcttaaaaat ccaaaacata gaactatttt gagaatgact tacatcaata
    39901 agatgtacgt tgatgacatc tgtgacagca tgaggggcat aagttctcct acttactatc
    39961 gtttgaagaa acaggcagta aaggagcttg atattattct ttcagaattg atagtaaatg
    40021 atagtaactg tacaggcatg aagtctaaaa tctgttaaaa tggtagtatc aagaattgaa
    40081 aagagaggtc tcagaattgg tagatggtta cctgtaatgt cagggggctg taatggcctt
    40141 ggaggttcaa accctcccct ctcctttgag tgtttgtgtc ccagaatggg gtaggcaaca
    40201 ggcttagcat tcatatatca ctcattaact tacaaatggt tgcggagcga ctggaccttg
    40261 catgattgcg tagctaatta tattccggat aagttataag ctagagggtt tgattccctc
    40321 agaggtttta aatgactaca aaaaataaaa aaagaagtca aaatttaata cgcacgcaag
    40381 gttgtagtcg ccttgcactt ttagggctta gcctagataa tctgtggtaa ctcaggaaaa
    40441 ggatgttttt aaatctatca aacatcctgc cagcaatggt caatctaagc aatgtaatct
    40501 taactatttc agttttggaa taggtgggcg aagttaaagc agaaagattc caacggcaag
    40561 gtgctgagga aatgcaaacg tggcagtttg gctgtgaaac gagtctataa gaggaaagag
    40621 gtatttggtt cgaggtgcaa caagagctta ataccatatc ttacaaaaat tgggcgcctc
    40681 ccaaaagtat gtaaggtgag ttgattgtcc gcaaaacaat cgataacaag caggcgctgt
    40741 gcattttgtt cttcaaaaga ggatgaaaca catggcgatg cgtgtctgtg atagatgaaa
    40801 gatgattttt atattttaag gctattcaag atagaaaaaa attcgaaaaa agcaaaagtc
    40861 atcgcccgtc gcaaacgaaa gtgtacttcg gcaattagat tgcctgctca agtctcgcaa
    40921 ggataagagt aaagtcaaag agtaaagcag cttagacttt tagcggggtc ttcgttaatt
    40981 gaaaaatggc ttagtagttt gtgatgtaag aagtgattgg tctaaccaat cgtgcatgag
    41041 tgatacaagt aggaatattt gtggacaaga taataaacta taagttatca aaagtcactc
    41101 gtttaaagca gtagtctcat gctagttaat ggatacatgg tagacggatt aagtcctgtt
    41161 tagggaattg aaacgtaggc aggttcgaat cctgtcgttc caattgcgat tttaattcgc
    41221 agagagaggt cttgaaaagg tcgcacatcg tgtggctttt ttgattgttt gaaaggtggt
    41281 gatggaaaat tgagtggatt gagaataaaa caaaagagat ttgcagatga gtacatcatc
    41341 tcaggtaatg cgacggaagc ctataagaaa gcaggttatc gtgtttctag tgatagagtg
    41401 gcaggcgttg aaggacataa gttactaaag aatcctaaga ttaaaagtta tatagatgaa
    41461 cagttgaaac agcttgattc tgaaaaaatc gcagaccagc aagaagtcct tagttatcta
    41521 acctcggtaa tgcgaggaga gacacaagaa cagactttga taagcatcgg agaattgggt
    41581 caaacgatta cggatattaa tgttggagca aaagacagaa tcaaggcagc cgaactatta
    41641 ggaaaacgtc ataggctttg gacagacaaa gtagaggcag acgtttctgg gacggtggtg
    41701 tttgcaaatg agtcagacat accagattaa acaaagtgat attgtaatcg acctacctaa
    41761 gacagtagga gctggatacg gacagttctg gcgctcaaga aatctttatc gtgttgtaaa
    41821 aggttcccgt ggttcgaaga agtccaagac aaccgctttg aattatgttg tccgtctttt
    41881 gaaatatccc tgggccaact tgcttgttat tcgtagatac tcgaatacca acaagcaatc
    41941 aacttatacg gattttaaat gggcgtgtaa tgtgttgggt gtgactcatt tgtttaaatt
    42001 caatgaatct ttgcctgaaa taaccataaa agcgactggt caaaaaatcc tattccgtgg
    42061 tttggatgat gaactcaaaa tcacatctat cacggtcgat gtcggcagtc tttgttgggc
    42121 atggtttgag gaagcatatc aaattgagac tgaagacaag ttcagtacag tagttgagtc
    42181 aatccgtggt agcctggatg tacctgattt ctttaaacaa atcacagtca catttaaccc
    42241 gtggaatgag aggcactgga tcaaacgtgt gttctttgat gaagagacta gccgagctga
    42301 tacattcgct actacaacta cttatcgatg caatgaatgg ctggatgaag tcgatatcaa
    42361 acgctatgag gatttgtatc atacgaaccc cagacgtgcg agaatcgttt gtgatggcga
    42421 atggggagtt gctgaaggtt taatctatga gaacgtgacc gtcaaggatt tcgataagga
    42481 tgaattgcta cgagatttag ctaataagtt atgtatcggt cttgactttg gttttactca
    42541 tgatccaact gctttgtgtt gttcgttgat aaatgacacg acgaaagaga tttatgtctt
    42601 tgatgaggcg tacaaggtcg gtcttataac caaagaagtt gctaagatga taaaggacaa
    42661 aggttatcat cgctcacaaa tcattgctga tagcgctgaa ttacgactga ttgaggaatt
    42721 aaggtcagaa catggtataa ctcgaattaa agagagtcgg aaaggtaagg atagtattat
    42781 ggcaggcgta tccaaattgc aaggatacgc tatttatgtg catccagatt gtaaaaacat
    42841 catggatgaa ttttatagtt actgctacca gcgagataaa gaaggcaact ggttgaataa
    42901 accagaggat aaaaacaacc acttgatgga cgctttgcgt tacagccttc aatgtatcga
    42961 aggtggaaaa gcaaccgtcc gcagacgttc tgattatggt ctatagagag gaaagacatg
    43021 taccaatatt taacctatcc acgggatgga tatgatgagg gttctttgaa gaaagacctg
    43081 atttacaaat tgataacgat acgtaacact gaaagctcac atttgaagaa gcttaaaagc
    43141 tactacttgg gtaagcatgc tatcttaaaa cacacgagac gcaacgtgaa cgcacccaat
    43201 taccagacgg tagctaatca tgccaaggat atcgcagaca tggctacggg ctattttatg
    43261 ggcaatccta tcaagtataa caatactgct gacggtgata tcgatgaact acttacagcc
    43321 tttgatggtg ctgagattga ccaagtagat gctcagaatg ctttgaacat ggctatctat
    43381 ggtcgtgctt acgagtacat ctatgctaaa gagggtttga ctgagttgga ttcaactagt
    43441 attgatccag aaaatacctt catggtctac gatgatagta ttgagcggaa gcctttgttt
    43501 gcggtctatt actatgaagt aaaagacgat acgaaagaca ctaccaagta ccaggctgag
    43561 gtctttacag aaaatctgca ctatcacatg gtgctgagaa gtacagattc aggaacaact
    43621 cagagcgagg aggcaacacc tcacaacctt ggtcaaatcc caattatcga gtatcgcaac
    43681 aatcactttg cgattggcga ctacgagcaa cagattagct tgatagacgc ttataattcc
    43741 ttgatgggta atcgtgtcaa tgacaaggag caggcagtag agtctatcct tgtcttatat
    43801 ggcacacagt tagcagacac tccagaagat gccaaggtag cgatgaagat tctttctgaa
    43861 gaaggtcttt tggaattgcc gggcgatagt gcaagagccg agttcttgaa gaatacgctg
    43921 gatgaaagtg ctacagaaat cttgcgcaca gctctgaaag aggatatcta cacattcagc
    43981 catgtgccta acttgactga tgagaacttc gcagggaata catcaggcgt agccatggaa
    44041 tttaagctga tgagccttga aatgattacc aagaccaagg aagcgaacta taagcgtgga
    44101 ttaagacaac gtattgcgat ttttgctcat tacttgggta tgaagcagat tgctttagag
    44161 tctcattcaa tcgttccaca attcagccgt ggtttgccta aaaacttgct ggaaatctct
    44221 cagattgtga acaatttgga aggtaaagtg accaataggc agcttatttc tctcttgccg
    44281 tttgtggaag accctgatgc tgaattggaa gccttggaag aagagaaaaa gaagaacatg
    44341 gaagacatgc cgatgtttaa ccaagacaac acgaaacccg aagacgaggt agaggatgaa
    44401 gaatcaggag tattgggcga agaggaaagc caatctgatt taccaacaga tggacaaggc
    44461 cgaaaagcag gcagaccagt tcgataaggt ctatcaggaa gccaagactt acttggataa
    44521 ggaagtcaat aagattttcg ataaattcca acgtgattat ggtctaagtc aggtagacgc
    44581 tagacaagtc ttgaagaaca tgaaagccaa gaaagacttg aatgaacttc gtaaggtgct
    44641 tgaagcaaga ccgaatgatc caaatatcca aagactacta gctgacttag acagtccggc
    44701 ttattctttc cgtatgaagc gtctagaacg tttgagcgat gatttagacc gtatgcgtga
    44761 atctatctat cattcggaga agacaggctc agatgccttt tatagcgacc tgatgaagga
    44821 tagttactac aaggctacct tttgacctac aacagcagac aggactagca tatggctttt
    44881 ctgggcttcc tgagagcgag attaaacatc tacagtcttt cagttgggta ggtgacggaa
    44941 gtacgtactc aacaaacatc tggaagaata cagggaagct tacatcaagc ataaaagatg
    45001 aattactcat aagccttatg acaggccgag atacacgaga aactgcacaa gcaattgctg
    45061 agcggttcaa tgtggggcag aacgatgcaa ggcgtttggt tcggacagaa tcagcctttt
    45121 ttcataacca aatggagcta ctcaactatg aggaagcgga tatagagaag tatatctttg
    45181 tggccgtctt agacaagcgt acatcacgca tttgtcagga gcatgacaat caggtctatg
    45241 atagggataa ggctgtccct ggtgtcaatt gtccgcctat gcacccttgg tgtaggtcta
    45301 ctactgtcgg atacgatgag gacgcagact acagcaagtt gaagcgcaga gcaaggaatc
    45361 cagagacagg taaagttgag tacgtgcctg ccgatatgac ttataaagag tggtatagca
    45421 agtatgttgc gaaagatgta aaaaatgaaa tacaagatta taagaaaagt gacaaaaccg
    45481 tttcaagata taatacccca aaattgtttt ctgatgttag taacgcatgg gatgaaattg
    45541 ggaggggtgg attatcgaaa gaacaacttg tagacttgct agaatctgaa tatgaattag
    45601 gtaatttttc gagcgatata gcaaaattga taggagtaag ttctgcttat atagatgtta
    45661 gtagtttagc tacttcatta gtgagacatg gacaacagta ctccttagat gagtttatgt
    45721 taataaaaga ggcggttcaa aaaccttatt tgattctaga taattcagag agggttgaaa
    45781 aatcaattat ttcatatgta aaaataccta acaaagataa ggtcattatg gaagcggtga
    45841 tggtgccacg agatgaaatg ctagtcattc actttaacaa ggtggggatt cgtcaagtta
    45901 aaaagaatga aaaaaatatg tcgacgcttt acaaaaaggg aaaataatgc tatactcttg
    45961 gtaaagatag aggttgagaa tctgtcacca acgcgccact tatagtgggt cgagaaatgc
    46021 aggagccccg acagtcctgc ctatcttgcg cttagatagt aatctaggcg cttttttgtt
    46081 gcaataaacc actataaacc gcatcgaaat ctaggcggtt ttcttatgcc ctaaccgtat
    46141 ggaatcccgt acggttttta tattgtccaa actgtaccga tgacaataaa agctgtgctg
    46201 ttccgtcgcc ggacgtaaag cgagactatc gagtggcgac gtaatcgctg gaggacaatt
    46261 atgtcagaag aaatcaatgc aactgtatct actgaatcaa ctgagactgt cgacactcaa
    46321 gaaaatgttg atacagtgca ggaagaaaag cacgaacgaa ctttcactcg tgctgaaatc
    46381 ggtaagatgc tatctgccga gcgctctaaa tgggaagctg agcaagaagc caaggaaaac
    46441 gaagctaaga agcttgctaa gatgaacgct gatgaaaaac agaaatatca gttggatcag
    46501 cgtgagcaag aactagctga ccgtgaaaag gctattgctc gtaaggaatt gaccgcagag
    46561 gctaaagcaa tgctaagtga acgtgactta cctgttgagt tagtaaatgt agtcgatttg
    46621 acaaacgcag agacggtatc tgaatctatc acctctatcc aaaaagcatg ggaagagtca
    46681 gttcagaagg gagtctctga acgtatgaaa ggtagtgcac ctatcaaaaa tgcacaaaca
    46741 gtccagcaag aagtcacgga aaaatggcgt aaagacttct tgtaataaaa gaaaagagga
    46801 aaaataaatg gcatttgaag aattaaacac agcagaatca cgcaagaaac atcttgggat
    46861 tattgaggat gtacttgcag taaattcata ttcaacacca cttgtgacat caagcgatgc
    46921 agtaaccttg caaggtcgct cttttacagt agcaactggt aacacaacag agttgaaaga
    46981 ctacaaacgt aacaaagaca acgaatttga tcacgttgaa gttgaagaaa aggtttatac
    47041 ccttgatgaa gaaaaatact ggggtcgttt cgtagatcaa ttggacgaac gtgactctaa
    47101 tggtcaagtg aatatcaatt atgttattgc ccgtcaggct gcagaagtag tcgctccata
    47161 tcttgatgaa ctacgttttg gtgcagcact tggaaacgta agtgacaatg ttgccatggg
    47221 taaaacagca ggagcgaaca acgcttataa tgcggttctt gatgtgtctg agaaacttga
    47281 tgagcttgga attacaaaag aacgcttgct cttcgtcact ccaagtttct acaaagcgat
    47341 caagtctgaa atcgttcgtc taccacatgg tgacgcagat aagaaagttc ttggaaaagg
    47401 atatgttggt gaattggatg attacacagt ctataaggtt ccttctaaat tcctgaaagg
    47461 tgttaatgcc cttgctactg ctccaggtgt tgttacatct ccagtacaag tagataatac
    47521 taagtacaac gataacattc cagggcgatt tggcgaattg gtagagcaat tgctttacac
    47581 tggtgcattt gttcttgaac acttcaagaa atacatcatc acaattgcag attctaagcc
    47641 tgctgctaaa aaatcagcac aaggtaaagt tgtaaaccgt gctaaagcgt ggaaaactgg
    47701 aacaacttac aaaaaaggcg aatcagtaac tcatgccgat aaagtctatg tagcggttaa
    47761 ggatatttct aattcagcaa ccgcaccaga cacagataca actaactgga aagaaaaaac
    47821 tggtaagaaa taggtccgag ttatgaaatt taaaatcaaa caagatttct atgattggga
    47881 atcaaatgtg aaacgactgg caggagagga acttgagatt actgaggagc gctatgccga
    47941 gctggctgac aattttgcca gcaatggtgt cgctatctca gatgttcttg aggaaatcct
    48001 ccctgaacct gagtttttcg aagaggatta atatgtctat agagttgctg aagaaaatga
    48061 caggcgaaga agatactcag cttctcatgt tgctccaaac gagggctaca aatcttatct
    48121 tgtcagagac taatcgaaca tctttgacac ctgctttaag tctcttaata cctgaggttg
    48181 ctatcgaact ccacaaccgc tcaggagcgg aaggagagca ttcaaggacc gaaggtggta
    48241 tagcagtagt ctacggagaa aacggcctgt ctacgggcct tttacagcgt atacgtatgc
    48301 atagactagc aagggtggca ggccatgttt ttgaagcaga gtagactgaa accttatcca
    48361 atgcgacggt ttgaaaagac tgtcactgag gaaggtgtcg caaaagaagg atatgtcaag
    48421 gaagctgaga caatccgtct tgagttgtgg ccagctagta gtaaactaca gtctgaattg
    48481 tatggcgagc gtgtcaatga tattttgaac gcaaatgcca acaagtcagc tacaatcaaa
    48541 gtgaaagatg gtgtgtgtat cgatagccag acagaagtga ctcacagggt tatttctaaa
    48601 aaggtctaca cacatcatca agttttggag ttagagcgtg tcagggctac taggggcaga
    48661 taggctcata gctaaatgta gacgattggc tagtaaaaaa actggagagg atatcgtctt
    48721 acgtgcggta cacaatgctg ctataaaggt tgtccaagct gatgcaagaa gactcgcacc
    48781 agcgagagat ggagagctta taattagtat caaaactaga gcaaaaatgg acggagataa
    48841 ggctataggc gaagtttaca ccaaccttaa atacgctcct tacgttgagt ttggaacagg
    48901 accaatagga caagctaacc attcgggtat ctctccagag gtcagcgtaa cttacaagtc
    48961 taatccttgg tatgtgcatg aagaccaaat caatgtagga ccgtaccact ttcaaaagat
    49021 tggggagttc tacaagatgt atggtcaacc tgctcagcct tatctttatc cagctttgag
    49081 agacaatcaa gagcgtgtgt ctaagaatat ttcgaattat gtccgtagaa agataagaga
    49141 acaaatataa tgatcaatat caagcctgtt atttataaag aattgcaaaa ggtcgcagat
    49201 aatgtgactg atacttatcc tagcgattgg gagaatttcc cagtcgttat ttttttagaa
    49261 gaacaaaaca agccaggtga ttggtttgac gacaaggaac aaaaatcctc tattcgctat
    49321 aaggtggata tctttgatga taccagcact agtgagttag ctgttaaaat caatcagatt
    49381 tttgagtctt taggtttgcg aagaaccgac tgccaagacg tgccagatcc gtctcatttg
    49441 agacataagg tcatgcgctt tgaaggtgtc gttgatttag actcagagct tgtttttcaa
    49501 tttagaatgg agaattaaac atgttagcaa atggaattaa attggccttt agtgaaacga
    49561 aaggcaatta tcagaatctt gtagggctta aggaagtacc tgaatttggt atcgagcccg
    49621 aaaaagtaga aaatactact cttgcagata cggtgaagaa gtacgagttt ggtatcgggg
    49681 acgcaggaga acttaagtac aagttcgctt ataataattc aagcgcaaca gctccttacc
    49741 gtgtattacg taaggcagca gatggcaaga aaaaactcta ctttgaacaa acctacccag
    49801 acggtactaa ggtcactttt gaaggtcaag tatccgttaa actgggcggt ggcggcgtta
    49861 atgccgttat cgagttcaca cttaagattg cattgcagtc tgaattgaca ttcgttgatg
    49921 gaattggagg ttaattaaat ggcgttaaaa tacacaactt ggaaagttac tgacgaaaaa
    49981 gagttgaagc tacgtttgac atctcatcaa gctgcaactg tggaagaaaa aatcggcatg
    50041 aacttgttaa agattttcat gcctgaagct ggcgaagagt tcactttacc gcctttgaaa
    50101 gttatgctgt tgttagttca tggagccttg cagcagtatg aacatgggta ttcctttgaa
    50161 gatgtctacg acctatacga tgaatacgtg gataacggcg gagaccaaac aaccttcatg
    50221 acagaggttt taatgccact ctttgaagta tcgggtttta ctccacgagg aagcaagggc
    50281 aagaaagctt ccaagaagaa aatgacagta gtcgagtaat cttaacggta acgcagatta
    50341 ttgagaggct ttaccctatg tttttggaca tcgggggtaa gcctcttgat ttttgggatt
    50401 taacggtgct tgaaatcagg gaaatgattg aaagctacaa ccgtgtcaaa atccaagagc
    50461 gtaaagagaa gattattgac tcatacatac tttcgagaat gataactaat catgtttcct
    50521 tattactgtc caatgacgct aagattgctg agctttggga atatgcgcct gatttgtttg
    50581 tagaagagaa acaagcggta gaacaagaac gacaaagaca agcacttttg ttgcataagg
    50641 aacggatgcg tgattttgca gagagacata atcgaaaaag gaaggaggaa gtaaatggca
    50701 actcttgacg aattgaaagt catgattgac gctgagatag cgcctttcag gaaaaagatg
    50761 aaagaagtcg agaatcaggt caaaggaaca tctgaccaag tgaaaaatgc cactgccaaa
    50821 gttcgtgaac agtcgaattc aatcggtagt acgtttggta agctcgctaa gtttgctggt
    50881 tttgcaatcc ttggtaagaa attgcttgat gttgggatgt attcaacgca gacagctctt
    50941 gaagtatcag cgtctatgaa ccaaattaag cgacagatgg gtgagagttc gcaatctttc
    51001 ttaaaatggg ttaacgataa cgctaatgcc atgaatatgg gtgtgggcga ggctactaac
    51061 tatggtgcag tctactcaaa cttattttct ggatttatca aagacaccaa caagctaagc
    51121 gcttatactg ctaagatgtt gcagacgtcg gcagttgtcg ctgaaggctc agggcgcacg
    51181 attacagacg ttatggagcg gattcgctca ggtttgctag ggaatacgga agcgatagac
    51241 ttttgtcgca ccgcttagaa ataggcggat taagaactta ccaaaatcgg taaaactcta
    51301 aattttaagt aattaaaaca tgacgatacc gaggtaaact aagcaattaa aaaggcttag
    51361 tcaccgtaga gcatagggat tgaacctgtg ctttttgttt tgtcaaaaag tatagaataa
    51421 aatatcccca cgagtggtga gcacctagac aattcggttg taggtgaaaa tatatgccga
    51481 acttacaaga aattgtaaga agtatggata aaaagccatg cgataacatt attgagaaga
    51541 tctaggaatc aacgtcaatg tggctatgat tgagtccact gaagccttta agaagttcgc
    51601 aaacggacaa agctggcaac aattagacta ccaaacccag caacaaatcc gccttatggc
    51661 tatcctggaa caggctacag ccaagtatgg gaataccttg tctaattctg taaatggtcg
    51721 tatcagcctg tttaagtcgc ttatgaagga cgcagcattg aaccttggta actctatgtt
    51781 accgattatc aatgccatta tgcctgtctt gaactctttt gctatggttt tgaagaacgt
    51841 gacggctaaa ctcgctgagt ttatcgcttt gatgttcaac aagaaagcaa cagtgaaaga
    51901 tggtgttggt ggagcagttg gagacatggg taacgccatg aaagacgctg caggcggagc
    51961 aggagacctt gctgacgcag tagacgatgc tggagattca gcaggaggac ttgctgacaa
    52021 tcttggagac tccgccaaaa acgctaagaa agctgctaaa gagttgctag gtcttttggg
    52081 atttgatgag attaacatct tgcaaaaacc aaaagacgac gatgcaggcg gttctggagg
    52141 cggtggcaaa ggtggtaaag gaaagggagg cggtggcgga cctttcaaag acatcttgcc
    52201 agaagtcgag ttgaccgaca tggacaacca attcaagagc attttcgatg gccttgggga
    52261 taagctgaaa gggttgtttg attatctaaa aaaactctgg gatttattta aaaaaggttt
    52321 ttctctatcc tttagatggg atagtattga aagattaaag aatgcactac aaggcatttg
    52381 gaaatctatt aaagatatct ttgaagatgg tactgtattg caagcagctg caaggtttgg
    52441 agaaaagcta gcttttgctt taggacaaac gacgggcgct ctcgctaacg taatcatggg
    52501 tattgctgtc tttatcgctg aaagtctgaa taaatcactt aatgaaacga aactagatat
    52561 caaagcatgg ttaattcgta tgtttgatat tggtggggaa atcgtcgaaa gcgtcggaaa
    52621 tattgcccag agtatcggac aaattttcta cgattcaatt acaagtgaac tagctacaaa
    52681 tatgggcgca ggcctattca gtgctttcac atacgctttt atgggcgtga aagagataac
    52741 cgctaaatac acaagggata taatcggagc tattgaagaa actatcaccg aaaatcaggc
    52801 tggcataaca gaaatgttta cgggtctttt taaagctgta gatcctattg ctcaagcttt
    52861 atcaagctca atgaagaaac tttttgaaag tgttaattaa gtatacgatg agcatataaa
    52921 acctttgttt gaatcaagtt ccgccttgat gtcagatgta gttggtgctt ttgttaatgg
    52981 atggaatgat aatatccaac ctgtccttga aaagataggt cacggtttcg ccgatacaat
    53041 caaaaaccat attgaaccag ctttagaaaa aataggtggc atgattggaa gttttgccga
    53101 cttttctaaa gcgataaatg aagttttcgg cccagtcatt tcctttattg tagaaaagtt
    53161 aacggttgta ctagcccctg caattgaata cataagagaa gtttggcgtg ttttatttaa
    53221 cactatctct gatgtgattg gtggtattgc tgatatcatc aaaggggtat ttgatgtact
    53281 tacaggactt ttaactggag atggcgaaaa aatcaaagaa ggatttttga gtatatttgg
    53341 cggattaaaa gatatagtag ttagcgtctt tagtggcatt attgatcttg tatctggtgt
    53401 attgaaactg ctttgggacg ttgttgtcgc aatattcaaa agcatttggg acgcaattgt
    53461 agctatcttt tctggtgtca gctcttggtt tggagaaaag ttccaaggtg catgggatgc
    53521 tatcgttaac atcttcagta atctaggctc atggttcgga caacgttggg cggatgtgac
    53581 tagtgcttta gctaatatcg gggcatggtt tacgaatatg ttccaaaaag catggactgg
    53641 cttaacaaac atctttagca aactaggttc atggtttggc gatagatgga acgatgttac
    53701 aagtgcgctt tctaaagtag cgagctggtt tggcgagata ttcggaaaag cttttgacgc
    53761 agtaaaagat gcttttagtt ctattggcga cttctttaaa ggcgtttggg atactgtcaa
    53821 aagtatcttc gttaatgctg gtcagatggt cggcgaggca gtaggtggag cgtttaagag
    53881 tgcggtcaat gcggttcttg gaacgattga aaatgtagtc aatggtttca tcggaatgat
    53941 taatggagtt ttaggcgttg tcagaaactt acctggtcta ggatgggttg gtagtgtaag
    54001 cacagttagc ctccctcgtc ttgcccgtgg tggtatcgtc gatagtccaa caatcgccat
    54061 gattggtgaa gctggtaaag aggcggtcgt accacttgaa aatacaggat ttatccaaac
    54121 acttggacga gtagtcagca gtgcggtagt aaatgccatg gctggtgtta gtccacaagg
    54181 tggattctct ggcgacggcg acatcgttat ccaaatcgca ggccatgagt tcggacgggt
    54241 agccatccaa gaaatcaaca aggaacatga acgagcaggt caaaccttgc tcaagattta
    54301 ggaggttaaa tggcacaatt gacaatcaat ggggtggctg tgaagcctcc caaatctttt
    54361 caagtcggta ttcaagatat cgatggagag acagggcgta atgccaatgg cgatatggtg
    54421 cgtgaccgta tcacgaccaa acgaaaacta gactgtgaat ggggcatgct gactcaggaa
    54481 gaaatgagtc agcttttaaa tgctgtttca gcagtctttt ttgaggtctc atatcctgac
    54541 cctgttaaag gtcagacgac tgggactttc tacgtcggtg ataggacagc tcctagctat
    54601 agctttactg agaagtttaa accttggtct ggcgctaaat ttaatctggt agagaggtga
    54661 gaaaatggac gctttaatca gacgacagtt tgacagagct atgtttgcca aggataggac
    54721 gctggctatt cgtgttggtg attatgcttc acgagatatc aaagaggcta gttttgagta
    54781 tggctatatc aaaggcgata cttacaaacc cggtggaacg tgtgccggta gcggtaagat
    54841 tacctttacc agtatcatta ccacgttcaa taaactggat atactacacc ctgagattgg
    54901 tctattggtt gggactacct accagtgggt taagatgggg gaatacttca tcaatgatat
    54961 tgagattgac cgaaaccgaa acacaaccac gcttgaactc atggatggta tgtttaagct
    55021 caatcgtgag tatgtgacgg acttacattt tccagctgaa gtacgagagg ttattcagga
    55081 aatctgcctg aaaacaggca ttgagttagc gaatgactat ttcggaatca gcgctatgcg
    55141 ttaccatatc gagcaagttc ctgagggcaa gaaactttcc tttagggata tgctgagcgc
    55201 tatgactcag atgattggga tgtcttgttt cttcaacaga gaaggcaaga tggaaatccg
    55261 tgatttgact gagtccaata tcacgatcaa cgctgacagt tacttcttgt atggcttgac
    55321 caagagtgag attgagtatc agatatctgg tatcacttgt aagacggaca agaagtctct
    55381 gacggtcggt atgaagacag gtcggtcttt ggaactggac aatgtcttca tgacccagag
    55441 cgctttaaat gacctgtatt acaaactgaa aaacctaact tactatccgt ataatctcaa
    55501 ctaccaagga catttgttac ttgaggttgg gcagtgggta accattcaga ccaacaagaa
    55561 agagactttt aaagttcccg tgttaagtca gagctttacc tttaaaggtg gtctgagagg
    55621 tcgtatcagt gcagatagta aggccggaaa cgatacccag tattcttacg agggtacgat
    55681 taccaagcag attaagcaac aagatggcat tgaagccaaa atccaagcgc agattgaagc
    55741 agcagataaa gattctgacc aaaaggtcga caaaatcaaa aaagacttta acgatcaagt
    55801 agaacttgcc aaagccagag ctgaagaagt caagcaagaa ctgtctgaca ctatcaatca
    55861 gcgctttaat agctttgaca acgggccatt gaaagaaact aagcgcaagg ctgaggaagc
    55921 tttgcgaaat gctggcgcaa gtaccctgct tgcacaggaa gttaagcgga ttggactgga
    55981 ttctgtcgct agacttggag cgtttaagtc gcagactacg agcgcacaaa cggctctgtc
    56041 aggtgacttg gacgctctga aacagacggt cacaagtgag gtcaatcaag cttcagagta
    56101 ccgcagaacg accacagagg tccttagtcg catgactggc cagatggacg gatttgcgac
    56161 gaaatctgaa gttagacaag atgtggctgg tctgacagag acatttgcta aacttaaaac
    56221 tgatacgaat aatttgattt ctggagctaa aagtgaaatc actctagcaa aaacagaatt
    56281 tcagaaaaca gctgatggcc tatctgctaa gatgtcagca gttgagcgtt acgttaatca
    56341 agatggtcag cgacaggaag ccctacagcg ctatactcgt gaggagagcg ctcgtcaagt
    56401 cagcgcggtt cgtgagcaga tatccagaga ttatgttggg aaatcggctt atcaagaaga
    56461 tgtgagaggt ctagaacgtc gatttagtgc gataagcacc cagacgaaca atgatatagc
    56521 taggaaaatc gctcagtaca agcagacagt cgatggacaa tttgcaagta ttacgtctca
    56581 aatagctggt aaggctaatc agactgactt ccagcgtgtt aaggaaacca gtaaacttta
    56641 cgagcggatt ctgggtaata gtaaaaacgg gattgcaaat acgattgcaa gaatggctat
    56701 gacccatcag ctctttcagg ttgaagtatc gaaaaacgac catctgaaaa ccgttcagag
    56761 gcagctggca ggttcctggt cggttcaaaa catcaacagt gcaggtgatt tgatttcggg
    56821 cattaatcta ggagccaatg gacataaccg ctttgttggg aaattgaccc acatcactgg
    56881 cgagaccctg attgacagag cagtcatcaa gtctgccatg gttgataagc tcaaaacggc
    56941 caattttgaa gctggttcgg taacgactac gatattagac gctgaagcgg tcacggctga
    57001 taaagtgaga tttgatgctg cgtttattag gaaaatgact gcaaatgacg cttttattga
    57061 ccaactgaca tctaaacgta tcttctctac taaggttgag tccgtcattt ctagttcaac
    57121 cttcctagaa gcctatcaag gacgaatcgg tggattcact attgggcgtt ttgctcaagg
    57181 aagaggtcgc tggatttctg gtatcaacca attctcagtt ggcatgggga atggtgaagg
    57241 aggaggctat aatggcgaaa ataccgcatt ttgggcgaac tggggttaca gttggaactc
    57301 tcctggcccc aatgcttggt atgtaacaac atcaggaaat atgtattgcc gaaacggagc
    57361 agatttccat gggaaggttg acttttcgaa ttcatcgaga gcaaactttt atgggaatac
    57421 tactttttct cgttctcctg tgttttcaaa tggtatcgaa cttggaagta aagacgtctt
    57481 tggtgatggt tggaatccca aaggcggaag gaatgcggtt gtttggtgga atcaggtcgg
    57541 tagtggtagc gtgaagtatt ggatggaaca aaaatcagac agacgcctaa aagagaacat
    57601 cacagataca gctgtgaaag ccttggacaa aatcaacaga ttaagaatgg ttgcatttga
    57661 tttcatcgaa agtaagaaac atgaggagat tggtctaata gctcaagagg ctgaaaccat
    57721 cgttccaaga attgtttcac gagatcctga gaatccagat ggctatctac atatagacta
    57781 taccgcttta gttccttact taatcaaggc cattcaagaa ttaaatcaaa aaatagaaaa
    57841 aatggagaaa acaatagcat gaataacaac atgttgacca atatcgcact taaagcaatt
    57901 caggagcttg ctcttgaaaa tagaaaacga acagatagat tggagaactt agaaaatgaa
    57961 cgcagaacag cttaaccaag ccttacaaat gacaattagt gaaatgtcaa caacttcaac
    58021 aaattcgatg attacaagta atgtcttgag tattcagttg gatgagcaaa gggaagagaa
    58081 tcaaagactt caagcacgag tggatgagct ggaagctctg cttgatgaac aaactaaacc
    58141 agcagacaaa ggagaataga catggcaaaa acaattcaaa acacagataa cttgctagac
    58201 cttacaaaaa tcacagaacc atttgatctt gcgagtgctt tgcgctacat gaaagaaagt
    58261 ggagagttca ttcgttgcaa gaatgtaaac gatgacttct atatgtatcg tgatgttcaa
    58321 aaacgtcctg tgttcgtaaa tggccgtcgc caattcaagg atgttgaaac cgtttgggcg
    58381 ttcaaccagt ggggtggtac aatcacaaca atcaacgtag ccattctgtt gaatcaggaa
    58441 ttctatatca tgaaatttga tgcagagggc aatcctgact ggacggatcc aacggtagaa
    58501 cctaaagaat aggaggttgt atgccaattg aagaagctga aaaaatcgct caaagtcagg
    58561 tagcttgggc gattttgttt atcttgcttt tctttattat cattcgatat cttatcaaga
    58621 cttcggacaa gcgagagaag aagattatgg atttgcacga gcaatcaaag gccgactcta
    58681 atagacgaga agagcgtttg atgactcatc tagaaaagac cactacagaa ttaaccacaa
    58741 tcactcacgc ggtcggagac attcaaaaag aaatggttcg catgaacgac cgcatggaag
    58801 aaatcgaaaa aggagaataa caaatgcaac aaattactga aatcattact aatggagcaa
    58861 tcagcatcct agtcattttg gcaggggttg tagttagggc agtcaaggaa tacctcgtca
    58921 aaaaaggtgg agaaaagact atcaagattg ttgaaatctt ggccaagaac gcagttaatg
    58981 ccgtggagca ggtagctgct gaaactggct acaagggaga tgaaaaactg gcacaggctc
    59041 gcgctaaaat tcgtgctgag cttacaaaat acaatattag catgactgac aaagacttag
    59101 acaccttcgt agagtcagca gtgaagcaga tgaatgacgc atggaaagga cgatagggaa
    59161 tggatatcga tagaaacaga ctacgtacag gcttgccaca ggttggggtg cagccttatc
    59221 gacaagtaca tgctcactca acaggcaacc gcaactcaac cgtacagaat gaagcggatt
    59281 atcactggcg gaaagaccca gaattaggtt ttttctcgca cgttgttggg aacggtcgca
    59341 tcatgcaggt aggacctgtg aacaacggaa gttgggatgt tgggggcggt tggaatgctg
    59401 agacctatgc agcggttgaa ctgattgaaa gccattcaac taaagaagag ttcatgacgg
    59461 actaccgcct ctatatcgaa ttgctacgca atctagcgga cgaagcaggc ttgccgaaga
    59521 ctcttgatac agacgacttg gcaggtatca agacgcatga atactgtacc aataaccaac
    59581 caaacaacca ctcagaccat gtggatccat atccatatct tgcaagttgg ggcattagcc
    59641 gtgaacagtt taagcaagac atcgaaaacg gcttgagcgc tgcaacaggc tggcagaaaa
    59701 atggcactgg ctactggtac gtacactcag acggctctta tccaaaagat aagtttgaga
    59761 aaatcaacgg tacctggtat tatttcgatg gctcaggcta tatgctttca gaccgctgga
    59821 agaagcacac agacggtaat tggtactact ttgaccaatc aggcgaaatg gccacaggct
    59881 ggaagaaaat cgctgagaag tggtactatt ttgatgtaga aggtgccatg aagacaggct
    59941 gggtcaagta caagaacact tggtactact tagacgctaa agaaggcgcc atggtatcaa
    60001 atgcttttat ccagtcagca gacggaacag gctggtacta cctcaaacca gacggaacac
    60061 tggcagacaa gccagagttc acagtagagc cagatggctt gattacagtt aaataaatag
    60121 aaaggaaact ttctaaattg ttctttcacc gcaggctcag gcttgcggtt tttttgtttg
    60181 ctcaaaaggg gcaaaaaagg ggcaaaagtg tcgtaaatct ctgtaaaatg atgtaaaaac
    60241 atttatttaa aagctcaaaa tatagctgtt ttaaaaggta ttgtaagata tagtaaaacg
    60301 atgtaaaggt atttttaaat gcggatgaat tataaaacca cgaatcctat gtgactcgtg
    60361 gttctttttt ataaactggt agagtgtttt ggttgtactt tttgttcagg gtcaatgtag
    60421 ttgatagcgt tgttgacagc agttggagct tctccgaggc ctgtcgcaat cagatcaatt
    60481 tttccgtcat agtagcagca gtcaccgata gcatagatac ctgcttggct ggattcctgt
    60541 ttgctgttga cgataatctt gtgacggttg aggtcgagcc cccagttttt aaggttaccg
    60601 acagaagatt tgaaaccata gttgacaaag aggtggtcta ggtcaatggt ttcagtttca
    60661 tcagatttga cttttgtgat ttcaagttta tcaagcgttt ttccatctcc aaggagttgg
    60721 ctaggggtga atggtgtctt gatggttaca gatgattctt gcaaggcttg aacactgtgt
    60781 tccaaggcac ggaaattatc tctgcggtga acaagggtag ttggtgcgat tttttcaaaa
    60841 gccaaagtcc aatccacagc cgaatctccc ccaccaagaa tcgtcacttt cttaccagcg
    60901 tattgctgaa tgttagaaac gtggtagtgg atattttcat agccctcaac cccttcaagt
    60961 tccagcggac gtggtttgaa ggcaccgccc cccatagcga tgataactgt tttagtcagg
    61021 tgacttcctt tagaagttgt gatggcaaat tcttcttctt gtttgtcaat ctcaagaacc
    61081 gtttcattga gatgaatagg ggtatcaaat ccatttagct gttcaatcaa gcggttagtc
    61141 aactcttctc cagtcaggtt tgggaagcct ggtacgtcta ggatttcctt ttcagggtag
    61201 agaatagcag gttgtccacc tagctgggga agagagtcga tgatttgaac cttggcttgg
    61261 cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac caccacccac aatggtaata
    61321 tcatagagtt gagacatagt ttctcctttg ttttttctag tcagtttatt ttatcatatt
    61381 tttgttcaat ataaaatgga ctaggatagg gaaaaaaatg ccagaaaatg gtataatagg
    61441 acgaaagtgt tttgataggg aggatatcag ggatgaattt tcaacaatta tccaatctgc
    61501 aatattggac cagtttgttt gcaagtccat ggacgatagc tatcaatctg attgatattt
    61561 tgattgttgc ttatatttta taccatttta caaaaactat tgcaggaacc aagattatga
    61621 ttttggtacg tggagttttg gtgtttattt tagctcaaat ccttgcaaat atgattggtt
    61681 tgactacgat ttcttggtta atcaatcaaa ttattactta tggggttatt gcggcggttg
    61741 ttattttctc tccagagatt cggactggtt tggaacgttt gggaagagcg acagatttct
    61801 tttccaatgc ccctattagt gctgaggaac agatgattcg tgcctttgtt aagtctgttg
    61861 aatacatgag tcctcgtaaa atcggggcct tggttgctat tcagcgtgta cgtaccttgc
    61921 aggagtatat ttcgacagga attcccttgg atgctaagat ttctgcagaa cttctcatta
    61981 acatttttat tcccaacact cccctacatg atggtgcggt gattatcaaa gaagaacgta
    62041 tcgctgtgac gtctgcctat ctgcccttga caaaaaacac agggatttcc aaggaatttg
    62101 ggaccagaca tcgggcggct atcggtttat cagaagtctc agatgccttg acttttgtcg
    62161 tatcagagga aacgggagga atttcgataa cctataatgg aaggtttaag cacaacctaa
    62221 cacttgatga atttgaaaca gaattacgtg aaatcttact tccaaaagag gaagtgggtc
    62281 ttagttttaa agaacgattg ctaggaggat ggaaacatga aaaaaaatag tttatatatc
    62341 atatcctcac tcttttttgc ttgtgtttta tttgtctatg ctacggcgac gaattttcaa
    62401 aacagtacca gtgctaggca ggtaaaaacg gaaacctata ctaatacagt aacaaatgtc
    62461 cctattgaca tacgctataa tagtgataag tattttatta gcggttttgc ttcagaagta
    62521 tcagtggtct tgactggtgc aaatcgccta tcgctagcta gtgaaatgca agaaagtaca
    62581 cgtaaattca aggttactgc tgacctaaca gatgccggtg ttggaacgat tgaagttcct
    62641 ttgagcattg aagctttacc caatgggctg accgctgtgg cgactccgca aaaaattaca
    62701 gtcaagattg gtaaaaaggc tcagaaggat aaggtaaaga ttgtaccaga gattgaccct
    62761 agtcaaattg atagtcgggt acaaattgaa aatgtcatgg tgtcagataa agaagtgtcg
    62821 attacgagtg accaagagac attggataga attgataaga ttatcgctgt cttgccaact
    62881 agcgaacgta taacaggtaa ttacagtggt tcagtacctt tgcaggcaat cgaccgcaat
    62941 ggtgttgtct taccggcagt tatcactccg tttgatacaa taatgaaggt gactacaaaa
    63001 ccagtagcac caagttcaag cacatcaaat tcaagtacaa gcagttcatc ggagacatct
    63061 tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat agaaaaggat tttataacaa
    63121 tgggtaaata ttttgggact gatggagtcc gtggagaagc taacctagaa ctaacaccag
    63181 aattagcctt taaactagga cgttttggag gctatgttct tagtcaacat gaaacggaag
    63241 cgccgaaagt ctttgtagga cgtgacacac gtatttcagg ggaattgctg gaatcggcct
    63301 tggtggcagg tctcctttca gtagggattc acgtatacaa acttggtgtc cttgcaacac
    63361 cagcagtagc ttacttggtt gaaactgaag gagcaagtgc cggtgtcatg atttctgcta
    63421 gccacaaccc agcccttgat aacggaatca agttctttgg cggtgatggc ttcaaactag
    63481 atgatgaaaa agaagcagaa attgaagcct tgctagatgc tgaggaagac actcttcctc
    63541 gtccaagtgc agaaggctta ggaattttgg tagattatcc agaaggcttg cgtaagtatg
    63601 aaggatacct tgtttcaact ggaactcctc ttgatggaat gaaggttgcc ttggatacag
    63661 ctaatggagc agcttctacc agtgcccgtc aaatctttgc agaccttggt gcccaattga
    63721 cggttatcgg ggaaacacca gacggtctta acatcaacct taatgttggt tcaacacatc
    63781 cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc tattggtttg gcctttgatg
    63841 gagacagtga ccgcttgatt gctgttgatg agaatggtga catcgtcgat ggtgacaaga
    63901 ttatgtacat catcggaaaa tacctttctg aaaaaggaca attggctaaa aatacaattg
    63961 tgacaactgt gatgtctaac cttggtttcc acaaggcctt gaatcgcgaa ggtattaaca
    64021 aggcagttac tgcagttggt gaccgctacg ttgttgaaga aatgagaaaa tcaggctaca
    64081 accttggtgg tgaacagtct ggtcacgtta tcttgatgga ttacaatacc acaggtgatg
    64141 gtcaattatc agcagttcaa ttgactaaaa tcatgaagaa aactggtaag agcttatcag
    64201 agttggcggc agaagtaacg atttatccac aaaaattagt taatatccga gtggaaaacg
    64261 tcatgaagga aaaggccatg gaagtgccag ctatcaaggc catcatcgag aagatggaag
    64321 aagaaatggc ggggaacggc cgtatccttg ttcgtccaag tggaacagag cccctcttgc
    64381 gtgttatggc agaagcgcct acaacagaag aagtggacta ctatgttgat accatcacag
    64441 atgtagttcg tgctgaaatt gggattgact aaatcctaga aaactagatg aaaataaaaa
    64501 attatggtac aatagcttat aatattgtag ccgatggaga aagacatgaa tcttaaacgt
    64561 gaacaagaat ttgttagtca gtatcatttt gatgcgcgta attttgaatg ggaaaatgaa
    64621 aatggagctc ctgaaaccaa ggtggatgtg aatttccaat tgctccaaca tgaccaagaa
    64681 aatcaagtga cttccttgat tgtcatcttg agctttatga ttgtatttga taagtttgtc
    64741 attagtggaa caatctcaca agtaaaccat atcgatggcc gtattgtcaa tgaaccaagt
    64801 gaattgaacc aagaagaggt ggaaaccttg gctcgtccat gtttgaacat gctcaatcga
    64861 ttgacttacg aagtgactga aattgcatta gacttaccag gaattaattt ggagttctaa
    64921 tatgaaatta gctgttttca cagattcctc tgcttatctc agtgaagaga ccttgcaaag
    64981 agaagacttg tttgtcttgg atattcctgt caatattgat ggtgaggaat atgtcgaagg
    65041 catcaatctg tctgctgagg aattttacca aaaaatggct caggcttctg aattgcctaa
    65101 gaccagtcaa ccaagtattg ccaagttaga tgagatttta acttcgctca aagaacaagg
    65161 ctatacacat gccttggggc ttttcctatc ttctggaatt tcaggttttt accaaaatat
    65221 ccagtatatg gtcgatgact atgagggctt aaccattgct tttccagaca ctttgattac
    65281 aagtgctcct ctgggtatca tggttgaaag cgtctttaat tggcgtgatc agggcgatga
    65341 ttttgccagc attcaggata agctagccat tcaaatcagc cgtacgtcag cctttatcat
    65401 ggtagatgac ttggatcatt tagtgaaagg tggacgcctt tcaaatgggg ctgccatttt
    65461 gggcaatttg cttagcatta agccaatcct ttattttaac gatcaaggtg tgattgaagt
    65521 ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc ttaattgaaa ttatcaagga
    65581 aacaacggct tcaagtcaat acagggtcat tgtcattcat gggaatgctc ctgaaaaggc
    65641 tgaagaattg cgtcagcatt tgcttgattt tggcttgggt tcggatgttt cacttgctac
    65701 atttggtagt gtcattggaa cgcacctagg agcaggaagt attgctctgg gttatattcc
    65761 agtgatttag ttggcgcttc taggctagtt aagatgcctt gtatcttagc aattgaacac
    65821 ggactacctg cctcttgaaa aaagatgtct gtcttgcctt tcgtggaaag tcagtgccat
    65881 ttcctatttt ttatgggtgg ctaagatcct ttgtatcttg ataattgaac acgcctggaa
    65941 ccctgtgtga aaaagatagt tcttccaagg agtagacact tcttgatcag aattcctatt
    66001 ttcactttgt gttcttacag gctttgtatc ttagacagga gtagagatga gtattcgagt
    66061 aattattgcc ggttttaagg gaaagatggg tcaagctgct tgccagatgg tcttgactga
    66121 ttcagatttg gacttggtag cagttttgga tccttttgag tctgagtcag aatggcaggg
    66181 tattcctgtt ttcaaggata aggctgattt agctggtttt gaagcggatg tctgggtaga
    66241 ctttactact ccagctgttg cctacgaaaa tacacgtttt gctcttgaaa atggctttgc
    66301 tccagtagtt ggaacgactg gtttcacgag tgaagaaatt gcagagctaa aagaattttc
    66361 tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt gccttgggtg ctgtcttact
    66421 catgcaattt gcgacgcagg ctgccaaata tttcccaaat gtggagatta ttgagctcca
    66481 tcatgacaag aaaaaggatg ctccgagtgg aacagccatt aaaacagctg agttgatggc
    66541 agaggttcga gagtcaattc agcaaggtgc agcagatgag gaagagctga ttgctggtgc
    66601 tcgtggtgct gactttgatg gtatgcgcat ccactcagtt cgtttgccag gcttggtagc
    66661 tcatcaggaa gtcatctttg gcaatcaggg agaagggttg accctccgtc atgactccta
    66721 tgatcgcatc tccttcatga caggagtcaa tttgggaatt aaagaagttg tcaagcgtca
    66781 tgagcttgtc tatggattag aacacttatt atgagattaa cgcaaatgcc ttctgaattt
    66841 cagaaggctt taccagtatt agaaaaaatt aaagaagcag gctttgaggc ttattttgtt
    66901 gggggctctg ttcgagatgc ccttctccat agccctatcc acgatgtgga tattgcgacg
    66961 tcttcttatc cagaagagac caagcagatt tttccgcgaa cagccgatat cggaatcgag
    67021 catggaaccg tcttggtctt agatggggat gaggagtatg aggtaacaac ctttcggaca
    67081 gaggatgtct atgtggacta tcgcagaccc agtgcggttt cctttgtgcg ctcgctagaa
    67141 gaagacctca aacgccgtga tttcacagtc aacgcctttg ccttggatga gacaggagaa
    67201 atcgttgact tgttccatgg tttagaagat ttggaaaagc aagtcttgcg agcagttgga
    67261 gtggctagtg agcgtttcaa cgaagatgct ttacggatta tgcgtggttt ccgttttcag
    67321 gctagtcttg gttttgcact tgagccagaa acatttaaag ctatgaagac cttgacgccg
    67381 cttttggaga aaatttctgt agagcgtacc ttcgtcgagt ttgataaact cttgctggct
    67441 ccattttgga gaaggggctt ggcttccatg attgagagtc aagcttatga ctatctccct
    67501 gatatggcat ctagccggga caagctcaac agactgtttg atttggagac tgattttact
    67561 tttgaatcct ctgaacaagc ctggtcggct ttactatggg ctttggagat tgaaaatgcg
    67621 cagtcatttt tgaaattttg gaagacctca cgccagtttg ccaagcaagt tcaggatttg
    67681 ctgattattt tggctctgcg tgaaaatgga gaattgagca agcgagattg ttatcgcttt
    67741 gacatagatt tgcttttaca ggctgaaaat cttcgtcaag ctcaaggaaa agaagtcaac
    67801 ccacaagcca tcacagaaaa ataccaaagc ttgactatcc atgacaagaa agagattcag
    67861 attaatggcg gtattttgat caaggaatat ggctatcagc caggcccaga cttgggagag
    67921 attttaacag agattgagtt tgccattgtc gatggagaat tggagaataa tcgtgaagcc
    67981 atccatgctt acctgaggga gaaaaaatga gtgattttat cgttgaaaaa ctaagtaaat
    68041 ccgttggtga caagaccgtt tttagggata tttcctttat tatccatgac ttagacagaa
    68101 ttggtttaat cggtgtcaat ggaactggca agaccaccct tttggacgtc ctttctggtg
    68161 tttctggatt tgatggggat gtcagtcctt tttcagctaa aaatgattac cagattggtt
    68221 acttgactca ggatcctgat tttgatgata gaaagacagt tttggatacg gttctatcta
    68281 gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt gattatgctc gactatagtg
    68341 aggacaagca ggcgcgtttg gaacgtgtca tggcagagat ggactctctc caagcttggg
    68401 aaatcgagag tcaggtcaag accgttctta gcaaattggg cattcaagac ttatctactc
    68461 ctgttgggga attgtcaggt ggtctgagaa gacgggtaca gttggcacaa gtcttacttg
    68521 gcaaccacga cctcttgctt ttggatgagc cgaccaacca tctggatatt gcgattattg
    68581 agtggctgac cctctttttg aaaaattcta agaagaccgt cctttttatc actcacgatc
    68641 gttatttctt agacgctttg tccacacgga ttttcgagtt ggagcgagca ggcttgacag
    68701 aatatcaggg caattaccag gactatgttc gccttaaggc agaacaggac gagcgcgatg
    68761 cagctctact tcataaaaaa gaacaactct acaaacaaga actggcctgg atgcgcagac
    68821 aaccgcaggc gcgtgcgacc aagcagcagg ctcgtatcaa tcgtttccac aacttgaaga
    68881 aagaactttc aggtggcgtt gctgagacag acttaactat gaactttgaa accagtcgga
    68941 ttgggaagaa agtcatcgag tttcaggatg tttcctttgc ctatgaaaac aagcccattt
    69001 tgcaagattt taatctcttg gtacaggtca aagatcgtat cggaattgtt ggggacaacg
    69061 gtgttggaaa atcaacctta ctcaacttaa ttgcaggaag tcttgagtca actaaaggac
    69121 aagttgtgat tggggaaact gttcgcatcg cctatttctc tcagcaaatt gagggcttag
    69181 atgaaagcaa gagagttatc aattacctgc aggaagtggc agaagaggtc aagaccagtg
    69241 gcggttctac gacttcgatt gcagagttgc tggagcagtt ccttttccca cgttcgacgc
    69301 atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa acgtctttat ctcctcaaac
    69361 tgcttttgga aaaaccaaat gttcttcttt tagacgagcc aaccaatgac ctagatattg
    69421 caactttgac agtcttagag aatttcttgc aaggttttgc aggtcccgtt ttaacagtca
    69481 gtcacgaccg ctatttcttg gataaggtag cgaccaagat tctcgctttt gaggatggca
    69541 agattcgtcc tttctttggt cattacaccg actatcttga tgaaaaaact tttgaaacag
    69601 atatggccaa tcaagtgcaa aaggccgaaa aggaaaaagt ggtcaaggtt cgagaagaca
    69661 agaaacgcat gacctaccaa gaaaagcagg agtgggcaag tattgaaggt gatattgaag
    69721 ccttggaaaa acgtatcgct gctattgaag aggaaatgca ggctaacggc tctgactttg
    69781 gtaagctggc tactctccaa aaagaattgg atgagaaaaa tgaagcactc cttgaaaaat
    69841 acgaacgcta tgagtatctc agtgaatttg atagttaaga ctattcgaaa atcaaagtgc
    69901 aaactatgtc ggcttcacat tgccgactca agtacagcct gtgaccggct tcctaatttg
    69961 cactttgatt tttattgagt ataaaagaat agaaaaatcc cgtctcatga aaggatttct
    70021 ctattctttt ttggtttctt gatgaaagat attttgccag gtttcgtggc gacgccagat
    70081 actggtatgg atgataccat ctaactcata gcagatgagt ttggtttttt gactgatgga
    70141 agtaatttga atgtccttga tagcagaatt taactctttt ttggtcttat aagcctcttt
    70201 atccatctgc tctccatctt ggcgaatata gacaaaatca tcagtcaaga gttcttctag
    70261 ttggtttcct tggtcaatca attgttcacg cataagcaat tttttataga cattgtctaa
    70321 aatttcatcc tcagggatag gtgctggttc gatatggaca tcggtatcaa agacgccaaa
    70381 acgctcctcc agcatagact cgacctgatc cgcgatttca tggctttcaa aaacagacaa
    70441 gtcaggattc atctctagtg taatatccag gtagatgttg ctaccgtagg tgcgacctct
    70501 ttgcgatttg accttgctga ttttgggaat ttccatgata gccttttggt agtcctcgag
    70561 caggcggtcg tcaaagccat ctgaaagact aaaggaagat tcgatgaaga tatcataggc
    70621 agtcttcaag ataaagaaag tgatgatgat agcaaccagt ttatccacaa tcggataatt
    70681 gaaactacta gctaggatgg caatggcggt tccaagtgag gtaacagcgt cagaaagatt
    70741 gtccttagca gctgccttca gcgccttgga gttggatttc ttactgaggc gagtattgta
    70801 gagatagacc acaaacataa tcgctgcaga aatgattcct agagttgcac caagaggatc
    70861 aatgaccgtt tcttcccgac tgagaatctt ttgaatggta tctcttagaa catcgaaacc
    70921 gacatagaac atgatgatag aagtgatcaa gcttgccaaa tcttcaatct tccaatgacc
    70981 aaaacggtgg tcacggtctg caggctggcg cgccatccga atcccgatta agagggccac
    71041 atttccaatg atgtccgata cgttattaaa accatcggcc accaaactgg atgaatgaag
    71101 gagatgacca gctgctaatt tggctgcaga caagatcaaa taggtcgaaa tactgataat
    71161 ggctccacgc tcagctaact tgagatttga gatagattgc ttcattcaac ttcctttcta
    71221 gtcacatagc attctaccat tatactggtt ttcaaggaaa aattcaaata aggcagtttt
    71281 tactctttga aaactcccca aaatttggta taatggtact actcaaggga gtagctggca
    71341 gaaacctgtg atagtgtcgt cattccgaat tttatgctga aaagtatgct ttccggccct
    71401 atcttaaaca gcgagacttg ttatgattaa caggtctctt tttgtttgtc gtgaaaagat
    71461 atgacagaaa gagagtctgt tttgcacaca atgtcaagga ggagacacat gtcaaaagaa
    71521 caaaaacgcc aagcgtttta tactcagagc cctgaagagg tcttgcaggc tgtggatgcg
    71581 accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc ttgccgaatt tgggcacaat
    71641 gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat tcatcgagca atttaaggat
    71701 ttgatgatta tcatcctagt tgcggcagca atcttgtcag tcgtgacttc tggtggggaa
    71761 gatatcgcag atgccattat catcctagct gtggttatca tcaacgctgc ctttggtgtt
    71821 taccaagaag gaaaagctga agaagctatt gaagccctca aatccatgtc tagtccagtt
    71881 gcccgcgttc ttcgtgatgg acacatggca gagattgact ctaaagaatt ggtaccaggc
    71941 gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg acctacgttt gatagaagcc
    72001 aactctctta aaattgaaga agcagccttg acaggtgaat ctgtaccagt cgaaaaagac
    72061 ttgtcagtcg agcttgcgac agatgctggt attggtgacc gtgtcaacat ggccttccaa
    72121 aactcaaacg taacctatgg tcgtgggatg ggtgttgttg tcaatacagg tatgtacact
    72181 gaagttggtc atattgctgg tatgcttcaa gatgcggatg agactgatac accactcaaa
    72241 caaaacttga acaacctttc taaggtcttg acctatgcta tcttggtcat tgcccttgtt
    72301 acttttgtag tgggtgtctt cattcaaggg aaaaatccac ttggtgagtt gttgacttct
    72361 gttgcccttg ccgttgcagc cattccagaa ggacttcctg ctatcgttac catcgttctt
    72421 tctcttggta ctcaagtttt ggccaaacga cattccatcg ttcgtaagtt gccagcagtt
    72481 gaaacacttg gttcaactga aatcatcgct tctgataaga ctggtacgct gactatgaac
    72541 aagatgacag tcgaaaaagt cttctacgat gcggttctac atgactcagc tgatgatatt
    72601 gaactaggtc ttgaaatgcc actacttcgt tcagttctct tggccaatga tacgaaaatc
    72661 gatgtggaag gtaacttgat tggtgaccca accgaaacag cctttatcca atatgccttg
    72721 gacaagggct atgatgtcaa aggtttctta gagaaatatc ctcgtgtagc tgaattgcca
    72781 tttgactctg accgtaagct catgtcaaca gttcacccat tgccagatgg tcgtttcctt
    72841 gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt gtcttcttcg tgataaggct
    72901 agggatattg ctccgattga tgagaaggtt acaaatctca ttcatacaaa caactctgaa
    72961 atggctcatc aagccttgcg tgtccttgca ggtgcttata agattattga cagcattcca
    73021 gaaaatctca cttctgaaga gcttgaaaat gatttaattt ttactggttt gattgggatg
    73081 attgaccctg aacgtcctga agccgctgag gctgttcgtg tggctaagga agcgggaatc
    73141 cgtccaatta tgattacagg tgaccaccaa gacacagcgg aagccattgc caaacgtttg
    73201 ggaatcattg acgcaaacga tacagaaggt cacattttaa ctggtgctga actcaatgaa
    73261 ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact ctgtttatgc ccgtgtgtct
    73321 ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac aaggtaaagt cgttgccatg
    73381 acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag ccgatatcgg tatcggtatg
    73441 ggaatcactg gtacagaggt ttctaagggg gcttctgata tgattcttgc agatgataac
    73501 tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg tcttctcaaa cattcaaaag
    73561 actattcagt acctactttc tgctaatact gctgaagtat taaccatctt cctatcaacc
    73621 ttgtttggtt gggatgtctt acagccggtt catcttttgt ggatcaactt ggtaacggat
    73681 accttcccag ctatcgctct tggtgttgaa cctgcggaac ctggtgtcat gaatcataaa
    73741 ccacgtggac gcaaggcaag cttcttctca ggtggtgttt tgagttctat catttatcaa
    73801 ggtgtactcc aagcagctct tgttatgagt gtttatggcc ttgcgattgc ttacccagtt
    73861 catgtgggtg acaatcatgc tattcatgca gatgccctaa cgatggcttt tgcaaccctt
    73921 ggtttgattc agctcttcca tgcctacaat gtcaagtctg tctaccaatc catcttgaca
    73981 gttggcccat tcaagtctaa gacctttaac tggtccatct tggtatcctt tatccttctc
    74041 atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc acgtaaccaa actagacttg
    74101 tcacaatggg gaattgttat ggctggaagc ttctcaatga ttatcatcgt cgaaatcgtt
    74161 aagtttattc aacgcaaact cggttttgac aagaatgcga tttaagggag gtttcggatg
    74221 tcagcatatt aattaccgac cgtatggcag gatgaagcta gtaatcaagg agcttttacg
    74281 gggctaaaca gaccaacagt aggtgcccgt ttcgaacaaa acttgccaaa aggagaacaa
    74341 gcttttcagc tttattcact gggaacacca aatggtgtga aggttactat cttattggaa
    74401 gaattactag aagctggttt taaggaagcg gcttacgact tgtataagat tgctatcatg
    74461 gatggggatc aattcggatc agactttgtg aagctcaatc caaattccaa gattccagcc
    74521 ttattggacc agtcaggtac tgaagatgta agagtctttg agtctgctca tattcttctt
    74581 taccttgctg agaaatttgg agccttttta ccaagtaatc ctgtggaaaa ggtagaagtt
    74641 ttgaattggc tattctggca agcaggtgca gcaccttttc taggtggggg atttggacat
    74701 ttcttcaatt atgctcctga aaaattggaa tatcctatta accgttttac aatggaagtg
    74761 aaacgccagt tggatttatt ggataaggaa ttggctcaga aaccttatat tgcaggcaat
    74821 gactatacga ttgcagatat tgctatctgg tcttggtatg gacagttagt tcaaggaaat
    74881 ctttaccaag gttctgcaaa attcttggat gcctcaagtt atcaaaatct agtaaaatgg
    74941 gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct tggaagtaac ttatacagaa
    75001 attaaatagc aaaaaagtca tcttcggatg gctttttgct acagttgagg gaaagggttt
    75061 gcagttatcg gcttttgtgc tataattgct ataatatagt aaaaagcaag aggagtgtga
    75121 ggaagtggaa aagaaaattg tgaaggatat cttattttta tctcaagtgt ctcagccggc
    75181 aagtcaggag gacctttatc ttgccagaga tttgcaggat acactcttag caaatcgtga
    75241 tacctgtgtt ggtctagctg ccaatatgat tggggtgcag aagcgcgtga ttatctttaa
    75301 tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt ctgtcctttg aaggatccta
    75361 tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga tcaactaagt gttatgaaac
    75421 cataagggtt gcctatcgtg acagcaagtg gcaggaacag accattacct tgacaggctt
    75481 cccagctcag atttgccagc atgagctgga tcacttggaa ggacgaatca tttaggagga
    75541 aagcaaatga aacgaatagt ctttgaactt atttttatcg caacgacctg gtatatcttt
    75601 ttaccgcccc ttaacctgac cagctgggaa tttctcttct tcctctgtgg gcatttgtta
    75661 gttgtggcaa tcttatttgg ctttggcaag gggataaacc ttgtcaaaac ggttcatgtg
    75721 cgccacggta aggcggaagc tgccttaaat cttgagggtt tcaaaatcaa tcggttaggg
    75781 aaaattctgt tagcttcgat tggaggaatt cttctcttgg cagctttggt ttccttggta
    75841 acttctagca tgtttcaggc taaaaattat gccaatgtag tcacggttac ggaaaaagac
    75901 tttactgaat ttcctaagag tgacaccagt aaggttccta tcctagatag aagtactgct
    75961 gaaaaaattg gagaccgcta cttgggttcc ctaaccgata aggtgtcgca atacgtagcg
    76021 gcagatacct atacccaatt gacaattgat gggaaacctt atcgggtcac accactagaa
    76081 tatgcagacc ctatcaaatg gtttaacaat caagccaagg gaatcggtga gtatatcaag
    76141 gtggacatgg taactggaaa tgcggatttg gtggacttga agacaccaat caagtattca
    76201 gactcggagt attttaaccg tgatgtcaaa cgtcacctgc gcttgaagta cccgaccaaa
    76261 atctttaaaa ctccatcttt tgaggtggac gatgagggca atcctttcta tgtagcaacg
    76321 gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg cttcagtcat tatcttggat
    76381 gctacaaatg gagaaaccaa ggaatacagc ttatcagatg ttccagaatg ggtggacagg
    76441 atctatccag cagaggaaac cattgagcaa attaactaca acggcaagta caaggacggt
    76501 ttcttgaatg ccatgatttc caagaaaaac gtgacccaga ctaccaaggg ctataattac
    76561 ttgtctatcg gtaatgacat ctatctctac acaggtgtga cgtcggctaa tgcggatgag
    76621 agtaatcttg gtttcatcct tgaaaatatg cgaacaggag aaatcactaa gtatagcttg
    76681 gcttctgcga cagaagaatc agcccgtgaa tcagcagaag gtgctgttca ggagaaatcc
    76741 tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca agcctctcta catcatgggc
    76801 ttaaaggaca atgctggctt ggtcaaagag tacgccctgg tagacgcagt cgagtaccaa
    76861 aatgttatcg ttgctactac agtggaagag atgctcagca agtatgccaa taaaaacgac
    76921 cttgaaattg acaatgcaac gacagaaagc atcaagggag tagtagcaga cctcaaatca
    76981 gctgttatca agggagacac tgtctacttc tttaaagttg atggcaagat atacaaggtc
    77041 aaggcttcag tatccgatga ccttccttac cttgaaaatg gtaaaacctt cgaaggtcaa
    77101 gtaggaaaag acaattatct caagaccttt aagctacggt aaaaataggt tttttcagaa
    77161 agtatatgtt ataatagagt aaattaagac taatggagga caaagaaatg ggtttttatt
    77221 tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt tctcagttca
    77281 aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca gcccttgttc
    77341 tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca aaccgaggtt
    77401 tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat atgaaaattt
    77461 taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca attcctttaa
    77521 aaccagaaag tcaggccgtg cttgatgcct tggctctcta ttctgccagt caattggaga
    77581 gtttctacaa ggtatcagct gagaaagcgg cggaagaatt tcaaaatatc caagctttga
    77641 aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt atgtaccgca
    77701 acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat catgtcttca
    77761 ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct caccgtttgg
    77821 attttttgat gaaattaaaa gtcgttggta agactttgaa gagccattgg aaggcagtct
    77881 atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca gagtttgaga
    77941 ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg gaggatagag
    78001 ggggtcagct gaagattcac tcaactatct ccaagaaggc gcgcggggcc tttctaacag
    78061 ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac tttgctggat
    78121 ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag gaagtataga
    78181 aatcagatat tttgtatttg gcaatatgta tcatcagcta ttttagttta taaatgagaa
    78241 aaaagcgaac aagctagtct tctgagtgtc agaaaagtag tcttgttcgc ttttattatg
    78301 ttatactctt cgaaaatcta aaatctcttc aagccacgtc agcgtcgcct taccgtatat
    78361 atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga gtagcttgcg
    78421 gctagcttcc tagtttgctc tttgattttc attgagtatt agtttataaa tgagaaaaaa
    78481 gcgaacaagc taatcttctg agtgtcagaa aagcagtctt gttcgctttt attatgttag
    78541 tttagttact tgatggcatt gaccaagtct tgagcttgtt tgtcaagtga gtttaggaca
    78601 gtttcttcaa gaaccaattt cccgtctgcc caggcagagt cattaacacg tgcagcagtg
    78661 aaatcgccaa cgacttgtgt acggataaat ggcaagaggt ctttgtagat agcgaagagt
    78721 tgatcgtgcc ctgcattggc tacagatgat acggtgacaa acttgtcttg aagggcagaa
    78781 gcaccacgtg tatcagacaa gtcaagggca cgagatagcc agtccagcaa gttcttcact
    78841 gtaccaggga tagagaagtt gtagactgga gagaaaatcc agatagcatc cgcaacgaga
    78901 actgcttcac gagcagcagc tacagctgga tgtgttggaa cttccaaatc ttggctgaag
    78961 agaggaaggg ctgaataatc aaggtagcta acttccgctt taccagcaag tgctttctca
    79021 gcttcgagcg ccatttggtg gttgaaagaa ccttgacgta gtgatccgac gataaataat
    79081 acttttttag acatgatgtg tctccttttt cttcaaattt cgagaactct ctcgttgtta
    79141 taaaatatat tacaacaaaa caaaagaact tgcaagaaat ttgctcagag tttatttgaa
    79201 aattgtaaaa tttcggaaac tctagtcatt tgtgactgaa aaagtaagaa ctgtttcact
    79261 ttcaaaatcg gttttgtttg aagggagaaa tagaattggt tgctcaaagc acagctttga
    79321 ggttgcagat aaagctgacg tggtttgaag agattttcga agagtattct tatattcact
    79381 tgtaataaag cttaatagat ggtaaaatag acgagtgaaa aaaagacaaa acaaagcaaa
    79441 aaataatcta ctgtggcagt atggtctagg gatgacgatt ttgtttgtgg ttatcagtgc
    79501 ttcctttctg tatatggttt ctcttagcat gaaaccctat caaacagcta aaagtgaagg
    79561 agaaaaatta gctcagcagt atgcaggatt agagcaggcc gatcaggttg atttatacaa
    79621 tggcttggaa tcttattaca gcgttcttgg tcgtaataaa cagcaagaag cacttgctgt
    79681 tctgattgga aaagatgatc ataagattta cgtttatcag ctaaatcagg gtgtttcaca
    79741 agaaaaagca gaaacggttt ctaaggaaaa gggagctggc gaaattgaca agattatctt
    79801 tggtcgttat caagataagc caatctggga agtcaagtca ggatctgatt tttatctagt
    79861 agattttgaa acaggagcat tggtcaacaa ggagggccta tgaaattatc caaccgtgtt
    79921 ttagaaatgg aagaaagtgt gactttggct gctggagccc gtgccaaagc actgaaggct
    79981 gagggcagag atattttgtc tctaaccttg ggtgagccag atttcactac tcccaaaaat
    80041 atccaagatg ccgccattgc atcgattcga gatgggcgtg cttcttttta tacagtaacc
    80101 tcaggtctgc cagagcttaa ggcggcggtc aatagctact ttgagcgctt ttacggctat
    80161 tctgtagcgt caaatcaagt gacagtcgct gcgggagcca aatattctct ctataccttc
    80221 tttatggctg tggtcaatcc aggtgatgaa gtcatcatcc caaccccata ctgggttagc
    80281 tatggagatc aggtcaagat ggcagaaggc gttcccgtct ttgtttctgc taaggaagac
    80341 aatcacttta aggtgaccgt ggagcagtta gaagcagctc gcactgacaa gaccaaggtt
    80401 ttggtgctga attcgccatc taatcccaca ggtatgattt acacccgtga ggaactcttg
    80461 gcaattggaa actgggctgt agaaaatgat attctcatcc tagcagatga tatctatggc
    80521 cgcttggttt ataatggtca tgagttcaca ccgatttcta gcctatcgga agcgattcgc
    80581 aagcaaacag tggtcatcaa tggtgtgtct aaaacctatg ccatgactgg ttggcggatt
    80641 ggttatgccg ttggagaagc agacattatc gctgccatgt ccaagattgc aggtcaaaca
    80701 acttcgaatc cgtcagcagt agcccaatat gcagcagttg aggctctatc aggtgagcaa
    80761 gatactgtag aaagcatgcg tcaggccttt gaggaacgtc ttaataccat ctatcccctc
    80821 cttgcagagg tgccaggatt tgaagtggtc aaaccacaag gggccttcta tctcttccca
    80881 aatgtcaaaa aggccatgga gatgaaaggc tacacggatg tgacagactt tacaactgtt
    80941 atcttagaag aagccgaagt ggccttggta acaggagctg gatttggagc accagaaaat
    81001 gtccgcctca gctatgcgac agacctagac acgcttaaag aagcagtcga acgcttgaaa
    81061 gcatttatgg gtagtgagaa taattgatca ttttgagatt aaggtaaagg atttacaaat
    81121 tttagaagga ttttatagga gttttctcgc tcctttggac tataaattgg cttttaagac
    81181 tagttctcta attagttttc tatccccgaa cagccctcat cctggtggtg atttttggct
    81241 gactcaggga acacaagatc ctgttcattt tgctttttta gcagaaaata aggaagaagt
    81301 tcaggcttgt tatgaggctg gcttagaggc aggtgggcga gacaatgggg ctcctggtta
    81361 tcgcagtgag catccgattt actatgctgc ttttatgatt gacctggatg ggaacaatat
    81421 agaggtggtt tgccataaag aataaaaaag aaaaggaaaa ataatgacaa aacgtgtaac
    81481 gattattgac gtaaaagact atgttggtca ggaagtgacg attggcgctt gggttgccaa
    81541 caaatcagga aaagggaaaa tcgccttctt acaattgcgt gatggaacag ccttctttca
    81601 aggtgtggct tttaaaccaa actttgtcga aaaatttggt gaagaagtgg gacttgagaa
    81661 gtttgatgtt atcaaacgct tgagccaaga aacgtctgtt tatgtgacag gtattgtcaa
    81721 agaggacgaa cgttctaaat ttggctatga gttggacatc acagacatcg aagtgatcgg
    81781 tgaatctcaa gactacccaa tcacaccaaa agaacacgga acagactttt tgatggataa
    81841 ccgtcacttg tggctacgct ctcgtaagca agtagctgtg ttgcaaatcc gtaacgctat
    81901 tatctatgca acttatgagt tctttgacaa gaacggtttt atgaagtttg acagcccaat
    81961 tctttcagga aatgcggcag aagattctac agaactcttt gaaactgact acttcggaac
    82021 gccagcctac ttgagccaat caggtcagct ttacctagaa gcaggggcta tggctcttgg
    82081 tcgtgtcttt gactttggtc cagtttttcg tgctgaaaaa tcaaaaacac gccgtcactt
    82141 gactgagttc tggatgatgg atgctgagta ctcatacttg acacatgatg agtcgcttga
    82201 cttgcaagaa gcttatgtga aagctcttct acaaggtgtt cttgaccgcg cgcctcaagc
    82261 cttggaaacc ttggaacgtg atacagaact cttgaaacgc tacattgcag agccattcaa
    82321 acgtatcact tatgatcaag ccattgacct cttgcaagag catgaaaatg atgaagacgc
    82381 tgattacgag catcttgagc atggtgatga ctttggttcg ccacatgaaa cttggatctc
    82441 aaatcacttt ggtgtaccaa cttttgtcat gaactatcca gcagccatca aggccttcta
    82501 catgaaacca gttcctggaa atccagagcg cgtgctttgt gcagacttgc ttgctccaga
    82561 aggttacgga gaaatcatcg gtgggtctat gcgtgaggaa gactacgatg cccttgtcgc
    82621 taagatggat gaacttggca tggatcgtac agagtacgaa ttttaccttg accttcgtaa
    82681 atacggtaca gttccacacg gtggatttgg tatcggtatc gaacgtatgg taaccttcgc
    82741 agcaggaaca aaacacatcc gtgaagccat tccattccca cgtatgttgc atcgtatcaa
    82801 accgtaagaa taggaaaacg tccatgtggt gttttttcga attccagagt ttttacttgc
    82861 gtaaaaaatt tttttctagt ataatagttc attgtgagcg aacctcactt accccttgca
    82921 aagtcttggg gtcattagac caaaaggagg aacatatcaa tggctaaata cgaaattctt
    82981 tatatcattc gtccaaacat tgaagaagaa gctaaaaacg ctttggtagc acgttttgac
    83041 tctattttga ctgacaacgg tgcaactgtt gttgaatcaa aaacttggga aaaacgtcgt
    83101 cttgcatacg aaatcaaaga tttccgtgaa ggactttacc acatcgttaa cgttgaagca
    83161 aacgacgacg tagctcttaa agagtttgac cgtctttcaa aaatcaacgc tgacattctt
    83221 cgtcacatga tcgtcaaaat tgacgcgtaa gaaggtaaac tatgattaac aatgttgtac
    83281 ttgtggggcg tatgacacgt gacgctgagt tgcgttatac cccatcaaat gtagcagttg
    83341 cgacttttac tcttgcagta aaccgtacat ttaagagtca aaatggcgaa cgtgaggctg
    83401 attttatcaa tgtcgttatg tggcgccaac aggctgaaaa ccttgctaat tgggctaaaa
    83461 aaggctcact tatcggggtg acaggccgta tccagactcg tagttacgat aaccagcaag
    83521 gacaacgtgt ctacgtgaca gaggtcgtgg ctgagaattt ccaaatgttg gaaagccgta
    83581 gtgtgcgtga aggtcacaca gttggtgcct attctgcacc aactgcaaac tattcagcgc
    83641 ctacaaattc agtaccagac ttttcacgtg atgaaaatcc atttggagca actaatccat
    83701 tggatatttc agatgatgat ttaccattct aatggacaac taaaattata aaggagaaaa
    83761 aacatggctc aacaacgtcg tggcggattc aaacgccgta aaaaagttga ttacatcgca
    83821 gcaaacaaaa ttgaatatgt tgattacaaa gatactgagc ttcttagccg tttcgtttca
    83881 gaacgtggga aaatccttcc tcgtcgtgta acaggaactt cagctaaaaa ccaacgtaaa
    83941 gtaacaacag ctatcaaacg cgctcgcgta atggctttga tgcctttcgt aaacgaagat
    84001 taaagaaaag
//
LOCUS       DAVFJR010000006        59072 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVFJR010000006 DAVFJR010000000
VERSION     DAVFJR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59072
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.006"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            115..1398
                     /gene="aroA"
                     /locus_tag="VU722_000564"
     CDS             115..1398
                     /gene="aroA"
                     /locus_tag="VU722_000564"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU1771596.1"
                     /translation="MKLKTNISHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVVTIQGVGMDGLKAPQNALDMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTIPLKKMGVSISGQTERDLPPLHLKGTKKLAPIQY
                     ELPIASAQVKSALMFAALQAQGESVIIEKECTRNHTEDMLQQFGAHLSVDGKKITVQG
                     LQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDLVAKSATLTVESSDLQGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTVDGMIVKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVSDGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            1391..1867
                     /locus_tag="VU722_000565"
     CDS             1391..1867
                     /locus_tag="VU722_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU1771597.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGISIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIATDKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            1864..2712
                     /gene="pheA"
                     /locus_tag="VU722_000566"
     CDS             1864..2712
                     /gene="pheA"
                     /locus_tag="VU722_000566"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU1771598.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQTVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAGKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            2709..3983
                     /gene="psr"
                     /locus_tag="VU722_000567"
     CDS             2709..3983
                     /gene="psr"
                     /locus_tag="VU722_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU1771599.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTIDARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINCRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFGLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            4262..5107
                     /locus_tag="VU722_000568"
     CDS             4262..5107
                     /locus_tag="VU722_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1771600.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLICYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTVFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            5097..6200
                     /locus_tag="VU722_000569"
     CDS             5097..6200
                     /locus_tag="VU722_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU1771601.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTINS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            6202..7188
                     /locus_tag="VU722_000570"
     CDS             6202..7188
                     /locus_tag="VU722_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1771602.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQRQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            7204..8673
                     /locus_tag="VU722_000571"
     CDS             7204..8673
                     /locus_tag="VU722_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU1771603.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFVARKKIKVANIGSSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNIQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVMIFVAKILTKENQYLLNKGEKNHV"
     gene            8666..9700
                     /locus_tag="VU722_000572"
     CDS             8666..9700
                     /locus_tag="VU722_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU1771604.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            9900..10637
                     /gene="mecA"
                     /locus_tag="VU722_000573"
     CDS             9900..10637
                     /gene="mecA"
                     /locus_tag="VU722_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU1771605.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            10788..12074
                     /locus_tag="VU722_000574"
     CDS             10788..12074
                     /locus_tag="VU722_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU1771606.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHSAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILATDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            12076..12945
                     /locus_tag="VU722_000575"
     CDS             12076..12945
                     /locus_tag="VU722_000575"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU1771607.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            13240..14178
                     /gene="msrB"
                     /locus_tag="VU722_000576"
     CDS             13240..14178
                     /gene="msrB"
                     /locus_tag="VU722_000576"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU1771608.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            14238..15962
                     /locus_tag="VU722_000577"
     CDS             14238..15962
                     /locus_tag="VU722_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771609.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRNRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELAFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            15964..17712
                     /locus_tag="VU722_000578"
     CDS             15964..17712
                     /locus_tag="VU722_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771610.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRGRII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            18014..19273
                     /locus_tag="VU722_000579"
     CDS             18014..19273
                     /locus_tag="VU722_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU1771611.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    19349..19484
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            19523..20023
                     /locus_tag="VU722_000580"
     CDS             19523..20023
                     /locus_tag="VU722_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU1771612.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARSLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            20099..20467
                     /gene="rplL"
                     /locus_tag="VU722_000581"
     CDS             20099..20467
                     /gene="rplL"
                     /locus_tag="VU722_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU1771613.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DATDAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            20669..20842
                     /locus_tag="VU722_000582"
     CDS             20669..20842
                     /locus_tag="VU722_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771614.1"
                     /translation="MTKELQSSRHIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            20839..21618
                     /locus_tag="VU722_000583"
     CDS             20839..21618
                     /locus_tag="VU722_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU1771615.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQDENDTAPVSHLAPSETEVSETKYSE
                     TDSLFIEDEEERNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            21717..23075
                     /gene="dcm"
                     /locus_tag="VU722_000584"
     CDS             21717..23075
                     /gene="dcm"
                     /locus_tag="VU722_000584"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU1771616.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            23059..23508
                     /locus_tag="VU722_000585"
     CDS             23059..23508
                     /locus_tag="VU722_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771617.1"
                     /translation="MKALNRESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            23501..23881
                     /locus_tag="VU722_000586"
     CDS             23501..23881
                     /locus_tag="VU722_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771618.1"
                     /translation="MIDLYLSKNNHRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            23894..24127
                     /locus_tag="VU722_000587"
     CDS             23894..24127
                     /locus_tag="VU722_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1771619.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            24130..24717
                     /locus_tag="VU722_000588"
     CDS             24130..24717
                     /locus_tag="VU722_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1771620.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFISLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLSVYVLFLL"
     gene            25094..25408
                     /locus_tag="VU722_000589"
     CDS             25094..25408
                     /locus_tag="VU722_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU1771621.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            25424..25810
                     /locus_tag="VU722_000590"
     CDS             25424..25810
                     /locus_tag="VU722_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU1771622.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            25839..27221
                     /locus_tag="VU722_000591"
     CDS             25839..27221
                     /locus_tag="VU722_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU1771623.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHL
                     EKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYD
                     KLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKE
                     DLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKE
                     NTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGM
                     MFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQA
                     TCEAEVAGVD"
     gene            27224..27376
                     /locus_tag="VU722_000592"
     CDS             27224..27376
                     /locus_tag="VU722_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1771624.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            27399..28604
                     /locus_tag="VU722_000593"
     CDS             27399..28604
                     /locus_tag="VU722_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU1771625.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            28647..28868
                     /locus_tag="VU722_000594"
     CDS             28647..28868
                     /locus_tag="VU722_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771626.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            28985..29482
                     /locus_tag="VU722_000595"
     CDS             28985..29482
                     /locus_tag="VU722_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU1771627.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            29457..29963
                     /locus_tag="VU722_000596"
     CDS             29457..29963
                     /locus_tag="VU722_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1771628.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            29947..32394
                     /locus_tag="VU722_000597"
     CDS             29947..32394
                     /locus_tag="VU722_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1771629.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            32397..34574
                     /locus_tag="VU722_000598"
     CDS             32397..34574
                     /locus_tag="VU722_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU1771630.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            34571..35572
                     /locus_tag="VU722_000599"
     CDS             34571..35572
                     /locus_tag="VU722_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU1771631.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            35569..36504
                     /locus_tag="VU722_000600"
     CDS             35569..36504
                     /locus_tag="VU722_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1771632.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            36748..36864
                     /locus_tag="VU722_000601"
     CDS             36748..36864
                     /locus_tag="VU722_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU1771633.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            36880..38799
                     /gene="tet(M)"
                     /locus_tag="VU722_000602"
     CDS             36880..38799
                     /gene="tet(M)"
                     /locus_tag="VU722_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU1771634.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            38918..39085
                     /locus_tag="VU722_000603"
     CDS             38918..39085
                     /locus_tag="VU722_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU1771635.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(39145..39282)
                     /locus_tag="VU722_000604"
                     /pseudo
     CDS             complement(39145..39282)
                     /locus_tag="VU722_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            39698..39781
                     /locus_tag="VU722_000605"
     CDS             39698..39781
                     /locus_tag="VU722_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEU1771636.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            39906..40643
                     /gene="erm(B)"
                     /locus_tag="VU722_000606"
     CDS             39906..40643
                     /gene="erm(B)"
                     /locus_tag="VU722_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU1771637.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            40998..41552
                     /locus_tag="VU722_000607"
     CDS             40998..41552
                     /locus_tag="VU722_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1771638.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            41556..44474
                     /locus_tag="VU722_000608"
     CDS             41556..44474
                     /locus_tag="VU722_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HEU1771639.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(44548..44769)
                     /locus_tag="VU722_000609"
                     /pseudo
     CDS             complement(44548..44769)
                     /locus_tag="VU722_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            45274..45696
                     /locus_tag="VU722_000610"
     CDS             45274..45696
                     /locus_tag="VU722_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU1771640.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            45693..45923
                     /locus_tag="VU722_000611"
     CDS             45693..45923
                     /locus_tag="VU722_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1771641.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            46384..46587
                     /locus_tag="VU722_000612"
     CDS             46384..46587
                     /locus_tag="VU722_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU1771642.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            46669..47886
                     /locus_tag="VU722_000613"
     CDS             46669..47886
                     /locus_tag="VU722_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1771643.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            48156..48746
                     /locus_tag="VU722_000614"
     CDS             48156..48746
                     /locus_tag="VU722_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEU1771644.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            48746..49582
                     /locus_tag="VU722_000615"
     CDS             48746..49582
                     /locus_tag="VU722_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEU1771645.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            49865..50164
                     /locus_tag="VU722_000616"
     CDS             49865..50164
                     /locus_tag="VU722_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771646.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            50154..50642
                     /locus_tag="VU722_000617"
     CDS             50154..50642
                     /locus_tag="VU722_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771647.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            50642..52519
                     /locus_tag="VU722_000618"
     CDS             50642..52519
                     /locus_tag="VU722_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU1771648.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            52540..52782
                     /locus_tag="VU722_000619"
     CDS             52540..52782
                     /locus_tag="VU722_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771649.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            52799..53653
                     /locus_tag="VU722_000620"
     CDS             52799..53653
                     /locus_tag="VU722_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU1771650.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            53707..54066
                     /locus_tag="VU722_000621"
     CDS             53707..54066
                     /locus_tag="VU722_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU1771651.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            54059..56374
                     /locus_tag="VU722_000622"
                     /pseudo
     CDS             54059..56374
                     /locus_tag="VU722_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            56386..>59072
                     /locus_tag="VU722_000623"
     CDS             56386..>59072
                     /locus_tag="VU722_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1771652.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFV"
BASE COUNT        19012 a        10341 c        12380 g        17339 t
ORIGIN      
        1 cagtttcaga attgctaaaa taagaaaata actatcctaa agtcaggaat ttttaaggaa
       61 tttctggctt tttatgataa aataggtaaa agtattgcaa gtatgaggtc cagtatgaaa
      121 ctaaaaacaa acattagcca cttacatggc agtatccgcg tcccaggtga caagtctatc
      181 agccaccgtt ccattatctt tggaagttta gctgagggag agaccaaggt ttatgatatt
      241 ttgcggggtg aagacgtcct ttcaaccatg caggtctttc gtgatcttgg tgtagagatt
      301 gaggataaag atggggttgt taccattcaa ggtgtcggta tggacggcct aaaagctcca
      361 caaaatgccc ttgatatggg aaattctgga acctcgattc gtctgatttc aggtgtcctt
      421 gctggtgcag acttcgaagt agaaatgttc ggagacgata gtctttccaa acgtcctatg
      481 gaccgtgtga cgattccact gaaaaaaatg ggcgttagca tttcagggca aactgagcga
      541 gacttgcctc cccttcactt aaaagggacg aaaaaactag cacctattca gtatgagttg
      601 ccaattgcct ctgcccaagt caagtcagcc ttgatgtttg cggccttgca ggctcaggga
      661 gagtcagtga ttatcgaaaa agaatgcacc cgtaatcata ctgaagatat gctgcaacaa
      721 tttggtgctc atttaagtgt ggatggcaag aaaatcacag tccaaggact tcaaaaactg
      781 acaggacaaa aggtggttgt tccaggagat atttccagtg cagccttttg gttggtcgca
      841 ggtttgattg ttccgaattc tcgtctagtg ctgcagaatg tggggattaa cgaaacgcgt
      901 accggtatta ttgatgtcat tcgtgccatg ggtggaaaat tagaagttac tgaaattgac
      961 ctagtggcta aatctgctac tttgactgtt gagtcttctg acttgcaagg aacagagatt
     1021 ggcggtgcct tgattccacg cttgattgat gaattgccta ttattgccct tttggcgacc
     1081 caagcccaag gtgtaacagt tatcaaggat gctgaggagc tcaaggtcaa ggaaacagac
     1141 cgtattcagg ttgtggcaga cgccttaaat agtatgggag cagatattac tcctacggta
     1201 gatgggatga ttgtcaaagg aaaatcagct cttcacggtg ctagagtcaa tacgtttggt
     1261 gaccaccgta tcggcatgat gacagctatc gcagccctct tggtttcaga tggagaggtg
     1321 gagcttgacc gtgcagaagc catcaatacc agctatccta gtttctttga tgatttggag
     1381 agcttgattc atggctaagg tgttattagg gtttatgggg gctggaaaat cgactattgc
     1441 aagaggattg gaccctaatt accttgatat ggatgctctg attgagaagc gcctaggtat
     1501 atccattgcg aattttttcg ctgaaaaggg agaatcagcc tttcgtcagg tagaatcaga
     1561 agtcctagct gatttactac aaacagacca agtcgtgtca actggaggag gagtggttat
     1621 ttctcagaga aatcgtgact tactcaagac taatacagat aacatctacc tgaaagcaga
     1681 ttttgaaacc ctctacctac gtatcgcaac tgataaggac aatcagcgac cgctttttct
     1741 aaataatagc aaggaagaac tagtagctat ttttcaagaa agacaggctt ggtatgagga
     1801 agtggctagt cgggttttgg atgtgaccaa gctaagccca gaggaaatta tagaggaact
     1861 aagatgaaaa ttgcttatct aggtcccaag ggatcatttt cacaccacgt tgtgcagaca
     1921 gcttttcctc atgaggaatt gcaggctttt gccaacatta cagatgtcat caaggcttat
     1981 gagcaaggat tagtggacta ttctgtggtg ccagttgaaa actctattga gggtagtgtt
     2041 catgaaacct tggactatct ttttcatcag gctcacatcc aaacagtagc agaaatcgtt
     2101 cagcctattc atcagcagtt gatggtggtt ccaggccata ctaagattga aaagattttt
     2161 tcacatccac aggcattggc tcaaggaaag aaattcatcg atgaacaata tccagaggct
     2221 caaatcgagg taacagctag tacagcttat gcggcccgtt ttatttccga acatccagac
     2281 cagccctttg cagcaattgc acctagaagt tctgctgaag aatatggatt ggaactgatt
     2341 gccgaggata ttcaggaaat ggaagccaat ttcacacgtt tctgggttct aggagctgga
     2401 aagcctagta ttcccttgca agcacaaact gaaaagatga gtttggcctt gacattacct
     2461 gacaaccttc caggtgcact ttataaggcc ctgtcgacct ttgcttggcg aggaattgac
     2521 ttgacaaaaa ttgaaagtcg tccactcaag acagcactgg gtgaatactt ttttattatc
     2581 gatgtggatt ataccgataa ggacttggtc cactttgccc aaaaagaatt agaagcgatt
     2641 ggaatccagt ataaaattct gggcgcctat cctatttatc caatatcaga ccatggaaag
     2701 gagagaagat gagtaaagaa aatcccttaa gtcatcatga gcagttgcgt tatgattatt
     2761 tgctaaaaaa tattcactat ctcaatgaga gagaaaaaaa tgagtttgcc tatttgcaag
     2821 aaaagctaac tcttgctagg ggaaatagta gctctagctt ggaacaagaa agagaagagc
     2881 aggttgactt accaagctat gcgaaccgga gtcgctcaca atccaaatca caagcactct
     2941 cttcacctcc aaaaaagaaa agacggaagc tccgtcttaa acgaattttt atggtgattt
     3001 tttcactttt agtctgtgtg gctttggcca tggtattcat gtttttgcgt ggttaccaag
     3061 atgctagcgc aaagaaaact attgatgccc gggcagctca agtagaagtc tttaatggtc
     3121 aggacactag agatggagtt aatattttaa tcatgggtac tgatggtcga atcggccaga
     3181 acagtgttga gacacgaact gactctatta tggtattaaa tgtcgggggc tcagataaga
     3241 aaatgaagct agtcagtttc atgcgtgata atttggtcta tatagatggt tatagtcaag
     3301 tgattaactg tagaaaacag acagataaca agttaaacgt agcctacgag ttaggagaac
     3361 aagaggggca aaaaggggca gaaatggttc gccaagtctt gaaagataat tttggcttgg
     3421 acattaagta ctatgccttg gttgatttcc aggcctttgc cacagcgatt gacacgcttt
     3481 tccctgatgg ggtgacgatt gatgctcaat tttcaacatt gaatgggcgt cccctaacag
     3541 aagctacagt cggagatgat ttatacgcta ccgagactga gtctccaacc caaaccatta
     3601 aagtcggaaa acagcagatg aatggctcga ccctgctcaa ttatgctcgt ttccgtgatg
     3661 atgatgaggc ggattacggc cgtacaaaaa gacagcaaca agttttaaca gcaattttag
     3721 agcaaattaa agatcctact aaacttttca ctggttctga agctcttgga aaggtttttg
     3781 ctatgacctc aaccaacgta ccctatactt tcctcctaac aaacggttta tctgttttgg
     3841 atggagcaaa aaatggtatt gaaaaattga cgattccaga actgggtgac tgggtagatg
     3901 cctatgatgt ttatggaggc ttgggcttgc tggttgatca aaacaaatat caaaccaagc
     3961 tcgctcaaat gggcttgaga taagataata ctcaatgaaa atcaaagtgc aaactaggaa
     4021 gctagccgca ggctgctaaa aacacagttt tgaggttgta gataagactg acgaagtcag
     4081 ttacctatac ctacggcaag gtgaagctga cgtggtttga agagattttc gaagagtata
     4141 agacagaaaa atcaaagttt gatagctatt tggatagcag tcaggctttg attttttaca
     4201 gtctgcaata gattttcacc ccttgtttgt ggtataatga aacgatacga tagaaagaat
     4261 aatgaacaat atgactgatt taaaagcaat tcaggctcgt agtctggaga tggctgaata
     4321 ttttgtggcc ttttgtaaag aacatgattt gatctgttat ctctgtggcg gaggcgctat
     4381 tggtgccctt cgaaacaagg gatttattcc ttgggacgac gacctagact tttttatgcc
     4441 tcgtaaagat tatgagaaat tagcagaatt atggcctcgt tatgcagatg aacgttattt
     4501 cttgtcaaag agtcacaagg attttgttga tcgtaatctt tttattacca ttcgtgacaa
     4561 ggaaaccacc tgtatcaagc cttatcagca ggatttggat ttgccacatg gtctggcctt
     4621 ggatgttttg cctttggatt attatccgaa aaatccagct gagcggaaaa aacaggttcg
     4681 ttgggccttg atttattcac tcttttgtgc gcaaactatt ccagaaaagc atggtgctct
     4741 tatgaaatgg ggaagtcgca ttttactggg tttgactcca aaatctctcc gttatcgcat
     4801 ctggaaaaaa gctgagaaag aaatgactaa gtatgatttg gctgattgtg atggcattac
     4861 agaattatgc tcaggtcctg gctacatgag aaacaagtac ccaatcacat cttttgaaga
     4921 caatcttttc ttgccatttg aaggaacaga gatgcctatt ccaatcggct atgatgtcta
     4981 tctcagaact gtttttgggg attatatgac gcctccacca gcagacaagc aggtaccgca
     5041 tcatgatgct gtcatcgctg atatggataa gtcttataca gaatacaagg gagaatatgg
     5101 tggctaagaa aaaaatctta ttttttatgt ggtctttttc tcttggaggt ggtgcagaga
     5161 agattctatc aaccattgtt tcaaatctgg atccagaaaa gtatgatatt gatattcttg
     5221 aaatggagca ctttgacaag ggatatgaat ctgttccaaa gcatgtacgc attttaaaat
     5281 cccttcaaga ttatcgccaa accagatggt tacgagcttt tttgtggaga atgagaattt
     5341 attttccaag actgactcgt cgtttgcttg taaaagatga ttatgatgtt gaagtttctt
     5401 ttaccattat gaatccacca ctgttgttct ctaaaagaag agaagtcaag aagatatctt
     5461 ggattcatgg aagtattgaa gaacttctta aggatagctc taaaagagaa tcacatagaa
     5521 gccagttgga tgctgcgaat acaattgtag ggatttcaaa aaagaccatc aattctatca
     5581 aggaagttta tccagattat gcttctaaat tacagacaat ctacaatgga tatgattttc
     5641 agactattct agaaaaatct caagagaaga tcgatatcga gattgctcct caaagtatct
     5701 gtactatcgg acggattgag gaaaataagg gttctgaccg tgtagtggaa gtgatacgat
     5761 tattacacca agagggaaaa aactatcatc tctattttat cggggctggt gatatggaag
     5821 aggaactgaa aaaacgagtc aaagagtatg ggattgagga ctatgtacat ttccttggtt
     5881 atcaaaaaaa tccttatcag tatttatctc agacgaaagt tctcttgtct atgtctaaac
     5941 aagaaggttt tcctggagtg tatgtggagg ccttgagtct gggactccct tttatctcta
     6001 cggacgttgg aggggctgag gaattatccc aagaaggacg atttggacaa atcattgaga
     6061 gcaatcaaga ggcagctcag gcgattacta attacatgac ttctgcctca aactttgatg
     6121 tcgatgaggc tagccaattc attcaacaat ttacaattac aaaacaaatc gaacaagtag
     6181 aaaaactatt agaggagtag catggaaact gcattaatta gtgtgattgt gccagtctat
     6241 aatgtggcgc agtacctaga aaaatcgata gcttccattc agaggcagac ctatcaaaat
     6301 ctggaaatta ttcttgttga tgatggtgca acagatgaaa gtggtcgctt gtgtgattca
     6361 atcgctgaac aagatgacag ggtgtcagtg cttcataaaa agaacgaagg attgtcgcaa
     6421 gcacgaaatg atgggatgaa gcaggctcac ggggattatc tgatttttat tgactcagat
     6481 gattatatcc atccagaaat gattcagagc ttatatgagc aattagttca agaagatgcg
     6541 gatgtttcaa gctgtggtgt catgaatgtc tatgctaatg atgaaagccc acagtcagcc
     6601 aatcaggatg actattttgt ctgtgattct caaacatttc taaaggaata cctcataggt
     6661 gaaaaaatac ctgggacgat ttgcaataag ctaatcaaga gacagattgc aactgcccta
     6721 tcctttccta aggggttgat ttacgaagat gcctattacc attttgattt aatcaagttg
     6781 gccaagaagt atgtggttaa tactaaaccc tattattact atttccatag aggggatagt
     6841 attacgacca aaccctatgc agagaaggat ttagcctata ttgatatcta ccaaaagttt
     6901 tataatgaag ttgtgaaaaa ctatcctgac ttgaaagagg tcgctttttt cagattggcc
     6961 tatgcccact tctttattct ggataagatg ttgctagatg atcagtataa acagtttgaa
     7021 gcctattctc agattcatcg ttttttaaaa ggctatgcct ttgctatttc tagaaatcca
     7081 attttccgta aggggagaag aattagtgct ttggccctat tcataaatat ttccttatac
     7141 cgattcttat tactgaaaaa tattgaaaaa tctaaaaaat tacattagaa cgggggtgac
     7201 caagtgattg atgggaaacg attattattt agtttgacca tagtcagtta tgccttgacg
     7261 ctagtaagtg gaattgtgta tctgtttaat aataataatg ttagcttact ttctacttta
     7321 ttgttcttgt tggttagtag cttaattgct tgttggaatg atatcaagta ttacttaatc
     7381 cattttattt tctatttaac catttttgta tttctggtat caagaccgac cattgattat
     7441 tttagggatg gtgctttgga tacctatcat ccaatagcct atcgttttgc cttcatagtt
     7501 gtcatggttt cgattctggg cttgactaca ggaggcgtcc tggctcgtta cttcgtagct
     7561 aggaagaaaa taaaagtagc aaatatagga agttctctaa aagaggttta tatcaagcgg
     7621 ttacgctttg tatcactagg agtttttctt ctaacttatc ctttctattt cattcggtta
     7681 tttgaacggc tcttgtatcg tttgcagact tcctactatg cctactatgc aaattttgaa
     7741 agtaaactgc cttattttac ctacattttg tctaccttta cggtctatgc aatgtgtatg
     7801 tatctggcaa ccaagccaaa gaaattgcag gccacagcag tgcttgtctc ctttattgca
     7861 gctaatacta ttcatttggc aattgggaca cgaaatccct ttattttaag tattttattt
     7921 gcttttgttt attactttat gcgggagcaa actgaaaaag gaaaatggat tgggtttaaa
     7981 gaaaagttag cgatttttgt aggttctcct attctcatgt tagcgatggg agtactcaat
     8041 tatgtacggg ataatatcca agtttcccat acaggtttct gggatatctt acttgacttt
     8101 atctataaac aagggactag ttttggtgtt ctggctcgag gttttctatt taacagtagc
     8161 ctcccttacc gagatttccg taattttact tttggtcctg ttcttgatta ttttgcaagg
     8221 gggagtttgg gagccatttt cggaggaaaa gcctttgaac atacaaccaa tagtgtggaa
     8281 ctagctattg atagtaatag ttatgcccac aatctatcct atcttgtctt gaacaaggaa
     8341 tacttgaaag ggcatggtat cggaagtagt tatatcatgg agttgtatac cgactatggt
     8401 atgattggag tctttctgct tagtttctta ctcggcgtat tatttatagc catgctgcaa
     8461 gtagcctatc gctcaaggac aatcctattt gctttatccc tactcatctt gaataatcta
     8521 ttctttatgc caagaagcag cttttcagaa agtttcttca atttatttac aatgcaattc
     8581 tggggaattg ttcttgtgat gatattcgta gcaaaaatac ttacaaaaga aaaccagtat
     8641 ctactaaaca aaggagaaaa aaatcatgtt tgaacattat tcagtagctg atttatttgc
     8701 aaatctatac aaaaaacgaa aagcaaatat tctagctctc atcgctttat ttgctctcat
     8761 tgctgtacca tttacaatta aagcagttag gaataaaaac actgtcaaag atacaacaag
     8821 ttattcaact tatcttatct ataaaatcac tcctccagaa gattcggcca aaacgatttt
     8881 gaatcatcaa attggtggtt atagtgattt ttatgggaaa ttgattgatg gtaatttgaa
     8941 tggagcttat cttttcaatg atgtagaacc cagtgagttg aaaaaaattg ccagtgaatt
     9001 agacacgaca gaaacaacct tgaaaaattc aacgaatgac tattggtgga aaaaattgac
     9061 cgtctactat atgattgacg atgcaggggt tggtgtgaaa attttgacat caagtaaaga
     9121 tgccaatgac ttgttagaga aaaaaattga tgggttgatt gagaaattta aacatgccta
     9181 tgcaaatgtg aaaattgaaa aactggaaac catcaactct aaagaattga acgcaaatgg
     9241 tgaaacagcg cttggcttaa atgtgaaaaa tctgattctt cgtttagttg ttattggagt
     9301 ggtttgtgtg attttggttg tgatgggaaa tgtgttagtt tatctcttta atccaacaat
     9361 caatagagta ggtgattttt ctcagtatca aattgatttt gtaacagaga ttacaacaat
     9421 tgctaaccta gcagatgttt tgtcatacaa aaatactgga caggaattga ccatcgttag
     9481 ctcaaataaa gctatcctag ataaattgaa acagagtcaa gaagctttaa aaggaatgca
     9541 ttttgtagat ttacaggatg tatcatctct tttggaaaga gatacagtcc ttcttgttga
     9601 agagtacgga gtgactcgtt ataagaaatt tgagcaaagt cttcaaattc tcagaaactt
     9661 aaatcgttct atcctcggcg tagcaacctt taaattataa gtattctgat gtataaggtc
     9721 ttcaaagtcg gctaagagcc gattttgaag gctttttcta tctgtctgca gaaattttct
     9781 tttggagtct cctatagaaa gaccctaggg aaaatctatc cgtatagagg agccttcttt
     9841 tgataaaatc gtaaaaatct agtataatag atagaactga aagtatgagg ttactagcaa
     9901 tgaaaatgaa acaaattagt gatacaactt taaaaatcac gatgtcttta gaggatttga
     9961 tggatcgtgg aatggagatt gctgactttc tcgttcctca agaaaaaaca gaagagttct
    10021 tttatgctat cttggatgag ctagagatgc ctgatagctt tctggataca ggcatgttga
    10081 gcttccgtgt gactccaaaa cctgataagg tagatgtctt tgtgaccaag tcaaagattg
    10141 accaaaatct agattttgaa gacttatcgg atttgccaga tatggaagaa ttggctcaaa
    10201 tgtctccaga tgaatttatc aaaaccctgg aaaaaagcat cgcagacaaa accaaggatg
    10261 atatcgaagc cattcaatct cttgagcaag ttgaagccaa ggaagaagag caagagcaag
    10321 ctgaacaaga agctgagagt aagaaagaac cttacatcta ctacatcctt tcttttgcta
    10381 agttggctga cttggtagct tttgccaaga cagtgacttt tgaaatggaa acttctgaac
    10441 tctacaaaat gaacgagcgc tattatttga ccattttagt ggatattgaa aatcatccaa
    10501 gcccatatcc agcttggctg ttggcccgta tgcgcgagtt tgcagacgat agtgatatca
    10561 gtcgctcagt cttacaagag tatggtcaag tcttgatgag tcacgatgca gtgctcaatc
    10621 tgcaaaaaat cggctaatcc tttctggaaa gctattttca gattttaaga agagcgaatc
    10681 gtctgattcg ttttttcttt ttatactgaa atagtgattt actataatag gaattttcac
    10741 aaaattctgt tataatggct atattagaaa atttcgagga gataaagatg acagttaaaa
    10801 ttgctttact aggatttggt accgttgcaa gtggtgtgcc tttcctccta aaggaaaatg
    10861 gaggaaaaat caatcaatca gcacattcag atatcaaagt tgctaaggta ttggtcaagg
    10921 atgaagatga aaaaaatcgc ttgcttgcag cagggaatga ctttaacttt gtaaccaatg
    10981 tggatgatat tttatcagac caagatatta ctatcgtagt ggaattgatg gggcgtattg
    11041 agcctgctaa aacctttatc actcgtgcct tggaagctgg aaaacacgtt gttactgcta
    11101 acaaggacct tttagctgtc catagcgcag aattgctaga aatcgctcaa gctaacaagg
    11161 tagcacttta ctacgaagca gcagttgctg gtgggattcc aattcttcgt actttagcaa
    11221 attccttggc ttctgataaa attacgcgcg tgcttggagt agtcaacgga acttccaact
    11281 tcatggtgac caagatggtg gaagaaggct ggtcttacga tgatgctctt gcggaagcac
    11341 aacgtctagg atttgcagaa agcgatccga cgaatgacgt agatgggatt gatgcagcct
    11401 acaagatggt tattttgagc caatttgcct ttggcatgaa gattgccttt gatgatgtag
    11461 cccacaaggg aatccgcaat atcacaccag aagacgtagc tgtagctcaa gagcttggtt
    11521 acgtagtgaa attggttggt tctattgagg aaacttcttc aggtattgct gcagaagtga
    11581 ctccaacctt cctacctaaa gcgcacccac ttgctagtgt gaatggcgta atgaacgctg
    11641 tctttgtaga atctatcggt attggtgagt ctatgtacta cggaccaggt gcgggtcaaa
    11701 aaccaactgc aacaagtgtt gtagctgata ttgtccgtat cgttcgtcgt ttgaatgatg
    11761 gtaccattgg caaagacttc aacgaatata gccgtgactt ggtcttggca aatcctgaag
    11821 atgtcaaagc aaactactat ttctcaatct tggctacaga ctcaaaaggt caggtcttga
    11881 agttggctga aatcttcaat gctcaagata tttcctttaa gcaaatcctt caagatggca
    11941 aagagggtga caaggcgcgt gtcgttatca tcacacacaa gattaataaa gcccagcttg
    12001 aaaatgtctc agctgaattg aagaaggttt cagaattcga cctcttgaat accttcaagg
    12061 tgctaggaga ataagatgaa gattattgta cctgcaacca gtgccaatat cgggccaggt
    12121 tttgattcgg tcggtgtagc tgtaaccaag tatcttcaaa ttgaggtctg cgaagaacga
    12181 gatgagtggt tgattgaaca ccagattggc aaatggattc cacatgatga gcgtaatctc
    12241 ttgctcaaaa tcgctttgca aattgtacca gacttgcaac caagacgctt gaaaatgacc
    12301 agtgatgtcc ctttggcgcg cggtttgggt tcttccagct cggttatcgt tgctgggatt
    12361 gaactagcca accaactggg tcaactcaac ttatcagacc atgaaaaatt gcagttagcg
    12421 accaagattg aagggcatcc tgacaatgtg gctccagcca tttatggtaa tctcgttatt
    12481 gcaagttctg ttgaagggca agtctctgct atcgtagcag actttccaga gtgtgatttt
    12541 ctagcttaca ttccaaacta tgaattacgt actcgcgaca gccgtagtgt cttgcctaaa
    12601 aaattgtctt ataaggaagc tgttgctgca agttctatcg ccaatgtagc ggttgctgcc
    12661 ttgttggcag gagacatggt gaccgctggg caagcaatcg agggagacct cttccatgag
    12721 cgctatcgtc aggacttggt aagagaattt gcgatgatta agcaagtgac caaagaaaat
    12781 ggagcctatg caacctacct ttctggtgct gggccgacag ttatggttct ggcttctcat
    12841 gacaagatgc caacaattaa ggcagaattg gaaaagcaac ctttcaaagg aaaactgcat
    12901 gacttgagag ttgataccca aggtgtccgt gtagaagcaa aataaagaat agaagatagg
    12961 atggggaaac tcttgaccag agggtttcat atcctttttg tgaaaagaag tttatactca
    13021 atgaaaatca aagagcaaac taggaagtta gccgcaggct gctcaaaaca gtgttttgag
    13081 gttgtggata gaactgacga agtcagctca agacactgtt ttgaggttgc agatagaact
    13141 gacgaaatca gtaacatacc tacggtaagg tgacgctgac gtggtttgaa gagattttcg
    13201 aagagtatta gttaaaaacg tgataaagga gaaataaaga tggcagaaat ttatctagca
    13261 ggtggttgtt tttggggcct agaggaatat ttttcacgca tttctggagt gctagaaacc
    13321 agtgttggct acgctaatgg tcaagtcgaa acgaccaatt accagttgct caaggaaaca
    13381 gaccatgcag aaacggtcca agtgatttac gatgagaagg aagtgtcact cagagagatt
    13441 ttactttatt atttccgagt tatcgatcct ctatctatca atcaacaagg gaatgaccgt
    13501 ggtcgccaat atcgaactgg gatttattat caggatgaag cagatttgcc agctatctac
    13561 acagtggtgc aggagcagga acgcatgctg ggtcgaaaga ttgcagtaga agtggagcaa
    13621 ttacgccact acattctggc tgaagactac caccaagact atctcaggaa gaatccttca
    13681 ggttactgtc atatcgatgt gaccgatgct gataagccat tgattgatgc agcaaactat
    13741 gaaaagccta gtcaagaggt gttgaaggcc agtctatctg aagagtctta tcgtgtcaca
    13801 caagaagctg ctacagaggc tccatttacc aatgcctatg accaaacctt tgaagagggg
    13861 atttatgtag atattacgac aggtgagcca ctcttttttg ccaaggataa gtttgcttca
    13921 ggttgtggtt ggccaagttt tagccgtccg atttccaaag agttgattca ttattacaag
    13981 gatctgagcc atggaatgga gcgaattgaa gttcgttctc gttcaggcag cgctcacttg
    14041 ggtcatgttt tcacagatgg accgcgggag ttaggcggcc tccgttactg tatcaattct
    14101 gcttctttac gctttgtggc caaggatgag atggaaaaag caggatatgg ctatctattg
    14161 ccttacttaa acaaataaaa cagagagggt ggggtttccc actttcttca tttctagaat
    14221 atgaatagaa gggatttatg aaacacctat tatcttactt caaaccctac atcaaggaat
    14281 caattttagc ccccttgttc aagctgttag aagctgtttt tgagctcttg gttcccatgg
    14341 tgattgctgg gattgttgac caatctttac ctcagggaga tcaaggtcat ctctggatgc
    14401 agattggtct gctccttatc tttgcagtaa ttggcgtttt agtggccttg atagctcaat
    14461 tttactcagc aaaggcagca gtaggttttg ctaaggaatt gacaaacgat ctttatcgtc
    14521 atattctttc cttgcccaag gatagcagaa accgtctgac aacttctagt ttggtcactc
    14581 gcttgacttc ggatacctac cagattcaga ctggtatcaa tcaattcctg cgtctctttt
    14641 tacgagcgcc cattattgtt tttggtgcca tttttatggc ttatcgaatc tcagctgagt
    14701 tgactttctg gttcttagtc atggttgcca ttttgaccat tgtcattgta gggttatctc
    14761 gattggtcaa tcctctctac agtagtctca gaaagaaaac ggaccaactg gttcaggaaa
    14821 cgcgccagca attgcaaggg atgcgggtta ttcgtgcttt tggtcaagaa aaacgagagt
    14881 tacagatttt tcaaaccctt aaccaagttt atgctagatt acaagaaaag acaggtttct
    14941 tgtctagttt attaacacct ctgacctatc tgattgtcaa tggaactctt ctcgttatta
    15001 tctggcaagg ctatatttca attcaaggag gagtgctcag tcaaggtgct ctcattgctc
    15061 ttatcaatta cctcttacag attttggtgg aattggtcaa gctagccatg ttgataaatt
    15121 ccctcaacca gtcctatatt tcagccaaga gaatcgagga ggtctttgcg gaatctcccg
    15181 aaaacatcca ttcagaatta gaacaaaagc aagttaccag tggtcgggtt ttacaagtcc
    15241 aagaattggc ttttacctat cctgatgcgg cccagccttc tctgagagac atttcctttg
    15301 atatgactca aggacaaatc cttggtatca ttggggggac tggttctggt aaatcaagct
    15361 tggtgcaact cttacttgga ctttatccag tagacaaggg gaacattgac ctttatcaaa
    15421 atggacgtag tcctcttaat ttggagcagt ggcggtcttg gattgcctat gtacctcaaa
    15481 aggtcgaact ctttaaagga accattcgtt ccaacttgac tctaggtttc aatcaagaag
    15541 tatctgacca ggaactctgg caggccttgg agattgcgca agctaaggat tttgtcagtg
    15601 aaaaggaagg actcttggat gctctagttg aggcaggggg gcgaaatttc tcaggtggac
    15661 aaaaacaaag attgtctatc gcccgagcag tcttgcgcca agctccgttt ctcatcctag
    15721 atgatgcgac ctcagcactg gacaccatta cagagtccaa gctgttgaaa gctattagag
    15781 aaaattttcc aaacatgagc ttaattttga tctctcaacg aacctcgact ttacagatgg
    15841 cggaccagat tctcctcttg gaaaaaggtg agttgctagc tgttggcaag cacgatgact
    15901 tgatgaaatc cagtcaagtc tatcgtgaaa tcaatgcatc ccaacatgga aaggaggact
    15961 agaatgaaac gacaaactgt aaaccagacg ctcaaacgtt tagccgtaga tttagcaaac
    16021 catcccttcc tccttttcct agcctttcta ggaactattg cccaagttgg cttatcaatt
    16081 tacctaccta ttctgattgg gcaggtcatt gaccaagtcc tagtggctgg ttcatcacca
    16141 gttttttggc agatttttct ccagatgctc ttggtggtaa taggaaatac tctggtacaa
    16201 tgggccaatc ctctcctcta taatcgtcta atcttctctt ataccagaga tttacggggg
    16261 cgaatcatcc ataaactcca tcggttaccg attgcctttg tagataggca aggtagtgga
    16321 gagatggtta gtcgtgtaac cacggacatc gaacagttgg cagctggctt gaccatgatt
    16381 tttaaccaat ttttcattgg tgttttgatg attttggtta gtattctagc catgctccaa
    16441 attcatctcc tcatgactct cttagtcttg ctattgacgc cactgtccat ggtgatttca
    16501 cgctttattg ccaagagatc ctatcatctc ttccagaagc aaacagagac gagggggatt
    16561 cagactcagt tgattgaaga atcgcttagc cagcagacta taatccagtc cttcaatgct
    16621 caaacagaat ttatccaaag attgcgtgag gctcatgaca actactcagg ctattctcag
    16681 tcagccatct tttattcttc aacggtcaat ccttcgactc gctttgtaaa tgcactcatt
    16741 tatgcccttt tagctggagt aggggcttat cgtatcatga tgggttcaac cttgaccgtc
    16801 ggtcgtttag tgactttttt gaactatgtt cagcaataca ccaagccctt taatgatatt
    16861 tcttcagtgc tagctgagtt gcaaagtgct ctggcttgcg tagagcgtat ctatggagtc
    16921 ttagatagcc ctgaagtggc tgaaacaggt aaggaagtct tgaccagtga ccaagttaag
    16981 ggagctattt cctttaaaca tgtctctttt ggctaccatc ctgaaaaaat tttgattaag
    17041 gacttgtcta tcgatattcc agctggtagt aaggtagcca tcgttggtcc gacaggtgct
    17101 ggaaaatcaa ctcttatcaa tctccttatg cgtttttatc ccattagctc gggagatatc
    17161 ttgctggatg ggcaatccat ttatgattat acacgagcat cattgagaca gcagtttggt
    17221 atggtgcttc aagaaacctg gctcacacaa gggaccattc atgataatat tgcctttggc
    17281 aatcctgaag ccagtcgaga gcaagtaatt gctgctgcca aagcagctaa tgcagacttt
    17341 ttcatccaac agttgccaca gggatacgat accaagttgg aaaatgctgg agaatctctc
    17401 tctgtcggcc aagctcagct cttgaccata gcccgagtct ttctggctat tccaaagatt
    17461 cttatcttag acgaggcaac ttcttccatt gatacacgga cagaagtgct ggtacaggat
    17521 acctttgcaa aactcatgaa gggccgcaca agcttcatca ttgctcaccg tttgtcaacc
    17581 attcaggatg cggatttaat tcttgtctta gtagatggtg atattgttga atatggtaac
    17641 catcaagaac tcatggatag aaagggtaag tattaccaaa tgcaaaaagc tgcggctttt
    17701 agttctgaat aagccattct cttttgaaag tttatggacg aaaaaagttg ccttcgagtg
    17761 acttttttgt tacaatagct agaaaaattg ttcactgtaa tactcaatga aaatcaaaga
    17821 gcaaactagg aagctagccg taggttgctc aaagcacagc tttgaggttg tagataagac
    17881 tgacgaagtc agttcaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa
    17941 ccacacctac ggcaaagtga atctgaagtg gtttgaagag agtacaactt gtcttttaga
    18001 aaaggagcct acaatgaaag tctttcagca tgtaaatatc gtgacttgtg atcaagattt
    18061 ccatgtttat cttgatggaa tcttagcagt caaggattct caaatcgtct atgtcggtca
    18121 agataagcca gcgtttttag agcaagctga gcagattata gactatcagg gagcttggat
    18181 tatgcctggt ttggtcaatt gtcacaccca ttctgcaatg acaggtctga gagggatccg
    18241 agatgacagc aatctccatg aatggctcaa tgactatatc tggccagcag aatctgagtt
    18301 tactcccgac atgactacca atgcggtcaa agaagccctg acagagatgc tccagtcagg
    18361 aacaacaacc tttaacgata tgtataatcc caatggtgtg gatattcagc aaatttatca
    18421 ggtggtgaaa acttccaaga tgcgttgtta tttttctccg actctctttt cttcagagac
    18481 agaaacaact gctgagacta taagcagaac tcgatccatc atagacgaaa tcttaaaata
    18541 taaaaatcca aatttcaagg ttatggtagc acctcattct ccgtatagct gcagtagaga
    18601 cttgctggaa gcgagtttgg aaatggcaaa agagctaaat attccgctcc atgtccatgt
    18661 ggcggagacc aaggaggagt caggaattat cctcaaacga tacggcaaac gcccccttgc
    18721 ttttcttgaa gaactgggtt atttagatca tccgtccgta tttgctcacg gggtcgaatt
    18781 aaacgagaga gaaattgaac gcttggcatc ttctcaagtg gctatcgccc acaatcctat
    18841 cagtaacctc aaactggcat caggaattgc tccaattatc cagctccaaa aagcgggagt
    18901 agcagtcgga attgcgactg actcggttgc ttccaataac aatctagata tgtttgagga
    18961 aggaaggact gcagctcttc ttcagaagat gaaaagtggg gatgccagcc agtttccaat
    19021 cgaaacagct ctcaaggtac tgacaatcga aggggctaag gcccttggaa tggaaaatca
    19081 gataggaagt ctggaagtcg gcaagcaagc agattttctg gtcattcaac cacaagggaa
    19141 aattcatctc caacctcagg aaaatatgct gtctcacctg gtttatgcag ttaaatctag
    19201 tgatgtagat gatgtttata tcgccggaga acaggttgtt aagcaaggtc aagtcctgac
    19261 agtagaactt taaaagaaaa atcacgaaaa attttaaaaa aagtttgcaa aaatcttgca
    19321 ttcttttttt gactatgcta tacttatata cggtttaaaa aaactgccta agacagtagg
    19381 ggagctcgac tcataaatat cctaccgagg acaagacgta tcatgtaaaa agaagcgtat
    19441 tgtactttcg tgtctaggtt tgggcgcgtt tttctttttg aaaaattccc caagcaaaat
    19501 aattacggag gtgaacacac taatgagtga agcaattatt gctaaaaaag cggaactagt
    19561 tgacgtagta gctgaaaaaa tgaaagctgc tgcatctatc gtcgttgtag acgctcgtag
    19621 tttgacagtt gagcaagata cagttcttcg tcgtgagctt cgtggaagcg aagttgagta
    19681 taaagttatt aaaaactcaa tcttgcgtcg tgcagctgaa aaagctggtc ttgaagatct
    19741 tgcatctgta tttgttggac catctgcagt agcattttct aatgaagatg ttatcgcacc
    19801 agcgaaaatc ttgaacgact tttctaaaaa cgctgaagca cttgaaatta aaggtggtgc
    19861 aatcgaaggc gctgtcgcat ctaaagaaga gattcttgca cttgcaactc ttccaaaccg
    19921 cgaaggactt ctttctatgc tcctttctgt acttcaagcg ccagtgcgca acgttgctct
    19981 tgcagtcaaa gcggttgcag aaagcaaaga agacgcggct taatcttaag ctacatagcg
    20041 tagcctagct acgaaaaaaa ctattataaa atttaaaact tatttggagg aaataacaat
    20101 ggcattgaac attgaaaaca ttattgctga aattaaagaa gcttcaatcc ttgaattgaa
    20161 cgaccttgta aaagctatcg aagaagaatt tggtgtaact gcagctgctc ctgtagctgt
    20221 tgctgcagct gatgcaactg atgctggtgc tgctaaagat tcattcgacg ttgaattgac
    20281 atctgcaggc gacaaaaaag ttggtgttat caaagttgta cgtgaaatca ctggtcttgg
    20341 tcttaaagaa gctaaagaac ttgttgacgg tgcaccagca cttgttaaag aaggcgttgc
    20401 aactgcagaa gctgaagaaa tcaaagctaa attggaagaa gctggagctt cagttactct
    20461 taaataagag gcatatacca attagaaatc ggaatactat agtatcagcc ttttagaatc
    20521 gtgaacacat tttagaaact gataaattaa tttagtttcc taccaaaaac cctaccaaaa
    20581 attaatttgg cagggttttt ctttttaaca aatttatcgt ggagaacaat tgaatattgt
    20641 tctccttttt ttattttcag gaggaaaaat gacaaaagaa ttacaatcat cacgccatat
    20701 tgtcatttca tttttagtac gtgaaatggg aattgacatt gttgaggcca tctctcttat
    20761 ggctgaatta gaaaaaagtg gcttggttcg cttggaatca agtggagatt taatactcaa
    20821 agaacttgga ggagcgctat gaaacgaatt accgcaaatc aataccaaac ttcagaacgg
    20881 tattataaat tacctaaaat tctttttgaa gatgagaaat atatggatat gaaactagaa
    20941 gtaaaggtgg cttattctat tttaaaagat cgtttagaat tatctctcag tcgtggttgg
    21001 atagatgaag aaggagcggt ttatttagta ttttctaatt ctaaactgat gaagctatta
    21061 ggttgttcga agtcaaaatt actgtccatc aaaaaaactc ttaaagaata tgacttaatt
    21121 gatgaagttc aacagtcttc aagtgagaag gggagactag ctaataagat ttatttaggg
    21181 gaattatctt ctaccccagt aggtaattca aacaggccta gtgttaaaaa aagactaggg
    21241 caggatgaaa atgatacggc ccccgtctca catttagccc ctagtgagac tgaagttagt
    21301 gagactaaat atagtgagac tgattcttta tttattgagg atgaggagga gaggaatact
    21361 caacctatct tgaaaagaaa agtagaaaag gtcacaaaat atgatcgaga ttatatttgg
    21421 ggattggtac aagatcaatt tagacgagag gggttttctg aaacagccag tgaaattgct
    21481 atgactgatt ttgagagaat ctatcagtat gctcttgaca atgttcgctt tgttagacgt
    21541 gcggaagtac ttgctgaatt tgtgtttaat ggcttgtatt ctgtttggaa caaccgtgtt
    21601 agaaaaggag gtggttaaat gtcgccaatc gagtggatat tagttatgct cattgtcatt
    21661 tcaagtggag tgacagttct gacaatgata gtcgataaga aaggggtgat aaagaattga
    21721 gatttattga tttattttca ggtatcggtg gctttcgact tggaatggaa agtgttggac
    21781 acgagtgtat tggattttgt gagatcgata aatttgctag agaatcttat aagtccattt
    21841 ttcaaacgga aggagaaata gaatttcatg acatacgaga tgtttcagat gacgaattta
    21901 aaaaacttag agggaaagtc gatgtcatct gtgggggatt cccttgtcaa gcattttcaa
    21961 tcgcaggaag acgattggga tttgaagata ctagaggaac tttgttcttt gaaattgctc
    22021 gggcggccaa acaaatccaa ccacgttttc tttttcttga aaatgttaaa ggcctactca
    22081 atcacgataa gggacggacg ttcaccacaa tccttaccac acttgatgag ttggggtttg
    22141 atgttgagtg gcaggtgctt aacagtaagg attttggcgt tccccaaaac agagagaggg
    22201 tgtttattat cggacattct agaaagaaag gtacccgact cctatttcct ttcagacgag
    22261 aaggtcaagc aactaactct gagactttga aagcactagg aaatttgaat ccatcaaaaa
    22321 gtggaatgag tggtaaagtc tattattcag aaggtcttgc gccaacctta gttcgtggaa
    22381 aaggagaagg atttaaagtt gcgattcctt gtatgacacc agacagatta gaaaagagac
    22441 aaaatggtag acgtttcaag gataatcaag agccaatgtt tactttaaat actcaggatc
    22501 gccatggtat tgtcgttgtt ggagatttac caactagctt taaggaaact ggtcgcgtct
    22561 atggaagtga ggggctatct ccaacactga ctacgatgca aggtggagat aaaatcccca
    22621 aaatactgat tccagaacca atccaatttc taaaagtccg agaggcaacg aaaaaaggat
    22681 atgctcaagc agagattggg gattcaatca atttagaaag accaagttct cagtatcgtc
    22741 gtggtagagt tggaaaaggt atagcgaata cgttaacaac tagtgggcaa atgggagtag
    22801 tagtggctag ctatgaagga gaagataaac aagtttacca agtagctggt atcttaattg
    22861 atgggcaatt ttaccgtttg aggatacgac gaatcactcc taaagagtgt tttagactgc
    22921 agggctttcc tgattgggct tttgaagctg ctagaaaagt ctctagtaat agtcagctct
    22981 ataaacaagc tggtaatagt gtaaccgttc ctgtgattgc cgcaatcgca aaaaaattaa
    23041 aagaaataga ggaaaaagat gaaagcatta aatagagaat caatactaga ttgtgatgaa
    23101 ttagaaacag aattacatga cgcagaaatc aaacagctgg atgaacaaat atttttaatg
    23161 cctaattatc catgtgagtt tgaggtgaca tttttagatg attaccataa aaaacataat
    23221 tacccactat tttatgaatc ctatcttcaa aacattatgg aattccttga aagtcaggat
    23281 ataaagaacg gagctgatgc ctttgtagat gataatcaga atctagtttt tgttttatat
    23341 ggacaaggct atcgagccga gggaaaagag ggaatactta caacccaagt aactgtaaaa
    23401 gcttatgatg aagacaagca accgattaac ttcgcaaatt tattagattc cttaatcgta
    23461 tcagaatatc aaatggaacc gaatctttgg gaggtttccc atgattgatc tctatctaag
    23521 taaaaataac catagaaatc aacttctttt ggatttcttc caaaactatg gtatcgaggt
    23581 atcttgtcat tcagtttctg aaatgacaaa ggacaaatta attgagatga tgagctattc
    23641 ttcagattgt ttcgagtttt tatctcccaa tttattacga tttaagaacc gtgacaattt
    23701 aagattaacg gattttattg aaatgatctt aaaaaatcct gaactaacca tcagacttcc
    23761 tcttgcggtt tcgaataaaa gagtttatcc aaatctgaat ctggaggagg ctagagcttt
    23821 attgccaaga gatacgaaac aattgattta catggcacaa acacattatt tatctaacta
    23881 aaggagaagc aatatggctg aacgattttg ggagaacttg tccattattt tggctgaaag
    23941 aaatattagc tggattgagt taaccagaaa aatgtttgcg ggagagtttc actatccaag
    24001 tgaattgaac cgtttgtatc aaaagatacg ccactacaag atggaacaac gaatgcctca
    24061 aagtccatgg gtagaaagga ttgtgcaggt attagattta gattatgaag atttatttcg
    24121 gaggtaacta tgaaaagaat cattccagtt tatatattcc aacaagtaaa tgtcctattg
    24181 gtatctctat acttactgaa attgctttgt atcggtgagt taactatact acagattctc
    24241 tatggtgcgt cactcatttc ttttttatgg atgtatggcc aacgcaaaca agctcataag
    24301 gtcaatatga aatctaggat gaaatggctt ggtattggat tcattagcct actgattata
    24361 agtctatgtt ttagcctaat ccatgctcaa ggaaccacga atcaagcaaa cttaattgga
    24421 cttcaacatc aagttccttg gttttcattt ttattgttct taatcaatgc gagtatggtt
    24481 gaagaatttc tgtatcgaga aattttatgg aacttggtta gaaaattaga tattcgagtt
    24541 gctttgacaa gtgttttatt tgccttagca catcatccag gaaccattct agcttggtgt
    24601 ttatatgttt cacttgggat gtttttaggg cttgtacgct acaaatcgga cttatggggc
    24661 agtatggggc tacatttggt gtggaaccta tcagtctatg tcttattttt gctttaataa
    24721 tagctgttct gtcttacgta tggattaatt ttgaaataaa aatagcataa aaatctagtt
    24781 atccgcataa aaactggact tatcacactt tatcaaggtc aaaaccactc aatttactac
    24841 taatttacta cttatgaatg agctttgata cgacgattta tccttgaaaa gtgaagatat
    24901 aaagatactt ccaataaaat ttgaatattt aataggtaga cacttcaaaa aatgaggtgt
    24961 ctattttttt acccgatttt gaaaggaagt gaacttatga aaacaaaaaa tcaagaatca
    25021 aaaggtcgtt ccccactctt taagaccatc aaacattcat tcagccaata aaaaagaaag
    25081 gataggtaaa aatatggaac ttaaatttgt gattcccaac atggaaaaaa cattcggcaa
    25141 tttagaattt gctggcgagg ataaagtcgt tcagcgaaga atcaacggac ggctaactgt
    25201 cttatcaaga agctataatc tctattctga tgttcaaaga gcagatgata ttgtggtggt
    25261 gcttcctgct gaagctggcg aaaaacattt cggctttgag gaacgtgtga agttagtcaa
    25321 tccacgtatt accgcagagg gctacaaaat cggcactcgt ggttttacaa attacctttt
    25381 acatgctgac gacatgataa aagaataaag aaagagagga aaaatgatga gattagcaaa
    25441 tggcattgta ttagataaag acacgacttt tggagaattg aaattctctg ctctacgtcg
    25501 tgaagtgaga atccaaaatg aagacgggtc ggtttcagat gaaatcaagg aacgtaccta
    25561 tgacttaaaa tccaaaggac aaggacgcat gattcaagta agtattcctg ccagcgtgcc
    25621 tttgaaagag tttgattata acgcacgggt ggaacttatc aatcccattg cggacaccgt
    25681 tgctactgcc acctatcaag gagcagatgt tgactggtat atcaaggcag acgatattgt
    25741 gctgacaaag gattctagtt cattcaaagc tcaaccacaa gcaaagaaag aaccgacaca
    25801 agacaaatag tcgctaggta gaaaggagac tttttcgcat gaaacagcgt ggtaaaagga
    25861 ttcgcccatc tggtaaagat ttagtctttc attttacgat agcgtcactc ctgcctgttt
    25921 tcctgctggt tgtcggactg tttcatgtga agacaatcca gcagatcaac tggcaggatt
    25981 ttaacctatc acaagcagat aagattgaca ttccctattt aattatcagt ttcagtgtcg
    26041 caattcttat ctgcttgctg gtagcgtttg tattcaaacg ggttcgctat gatacggtta
    26101 aacaacttta ccaccgtcaa aaactggcaa agatgatact tgaaaacaag tggtatgaat
    26161 ctgaacaggt caaaacagag ggtttcttta aagatagtgc tggtcgtaca aaaaagataa
    26221 cctacttccc taaaatgtat tatcgactta aaaatggctt gatacagata cgggtggaaa
    26281 tcacgctggg aaaatatcaa gaccaactct tacacttgga aaagaaatta gagagtggct
    26341 tgtactgtga gctgacggat aaagagttaa aggattccta tgtggaatat actttgctct
    26401 atgacaccat agccagtcgt atttctattg atgaagtaga agctaaagat ggtaaacttc
    26461 gcttaatgaa aaacgtatgg tgggaatatg ataagctccc tcatatgttg attgctggtg
    26521 gtacaggtgg cggtaaaact tactttatac tgacactgat tgaagccttg cttcatacag
    26581 attcaaaact gtatattctt gacccgaaaa atgctgacct tgcggactta ggttctgtga
    26641 tggcaaatgt ctactataga aaagaagact tgctttcttg cattgaaaca ttctatgaag
    26701 aaatgatgaa acgtagtgag gaaatgaagc agatgaagaa ctataagact ggcaaaaatt
    26761 atgcttactt aggtctcccg gcacacttct taatctttga tgaatacgtc gctttcatgg
    26821 aaatgctggg aacaaaagaa aacaccgcag ttatgaataa gctgaaacag attgtcatgt
    26881 taggtcgtca agctggcttc tttctaatac tggcttgtca acgtccagac gcaaaatatt
    26941 taggcgacgg aatccgtgat cagtttaatt tcagagtggc tttaggtcgt atgtctgaaa
    27001 tgggctatgg catgatgttt ggcagtgacg tacaaaagga tttcttctta aagcgaatca
    27061 aaggtcgtgg ctatgttgat gtaggaacaa gtgtcatatc agagttttat actccccttg
    27121 taccaaaagg atatgatttc ttggaggaaa ttaaaaagtt atccaacagc agacagtcca
    27181 cgcaggcgac gtgcgaagcg gaagtcgcag gtgtggactg atcttgctgg ctggtgtggc
    27241 aatagccacg ccagcactta accccccgta tctaacaggg gggtacaaat cgacaggaaa
    27301 cagtcaaaaa aacattagaa aatcctttgg ttacaaggga tttacaaaat ttcagcgtat
    27361 gtcaaatggg ctttaaaagt tgacatacgc ctttttgatt ggagggattt ttactgaatg
    27421 aacaaacttg gttacagcat ttaaaagaaa aacgcttggc ttatggacta tctcaaaacc
    27481 gtttagctgt tgcgactggt attacaaggc agtatctaag cgatattgaa acaggaaaag
    27541 tcaagccatc agaggattta cagcagtccc tttgggaagc tctggaacgc ttcaatcccg
    27601 acgctcccct tgaaatgctg tttgattatg taaggattcg ctttccgaca acagacgtac
    27661 agcaggtggt cgaaaacatc ttacaactga aactgtccta ttttcttcat gaggactatg
    27721 gtttctattc ttattcagag cattatgctt taggcgacat attcgtcctt tgctcccatg
    27781 aactggacaa aggagttctg gtggaattga aaggtcgtgg gtgcagacaa tttgaaagct
    27841 atcttctggc acaacaaaga agctggtatg agttctttat ggacgttttg gtggctggcg
    27901 gtgtgatgaa acgccttgac cttgccatta acgataagac agggattttg aatatccctg
    27961 tactcactga aaagtgccaa caggaagaat gtatctccgt cttccgcagt tttaaaagct
    28021 atcgcagtgg cgaactggta cgcaaagagg aaaaggaatg tatgggaaac accctctata
    28081 tcggttcatt acaaagtgaa gtttatttct gtatctatga aaaggactac gagcagtaca
    28141 agaaaaatga tattcccatt gaagacgcag aagtaaaaaa ccgttttgag attcgattga
    28201 aaaatgagcg tgcctattat gcagtccgtg atttactcgt ctatgacaat ccagagcata
    28261 ccgcctttaa aattatcaat cggtatatcc gttttgtaga taaagacgat tccaaacctc
    28321 gttctgattg gaaactgaat gaagaatggg cttggtttat tgggaacaat cgtgaacgat
    28381 taaaactaac cacaaaacca gagccttact ccttccaaag gacgctgaac tggctatctc
    28441 atcaagttgc cccgacctta aaggttgcga ttaaacttga tgaaatcaac cagacgcagg
    28501 ttgtaaaaga cattctcgac catgcgaaac tgacagaccg acacaagcag attttgaagc
    28561 aacagtcagt aaaagaacag gacgtgataa caacaaaaaa ataactcaaa tacaaattca
    28621 ttgaatatag agaggagaac atttttatga attttggaca aaacctttat aactggtttc
    28681 tatcaaacgc tcaatcactg gtgcttttag caatcgttgt gattggcttg tatcttggct
    28741 tcaagcgtga gtttagcaaa ctgattggct ttttaattat tgcgattatt gcggttggct
    28801 tagtcttcaa cgctgctgga gtaaaagaca ttttactaga gctattcaat cgcattattg
    28861 gtgcttaaat aaaaccgttc ttttgtggaa tataagtggt tttcttatgt tccgcaaagg
    28921 aatggtacac caaacgaagt gcggtaggga tttttgaatc tctacaaaga aaggacgtga
    28981 atatatggac gatatgcaag tctatattgc gaatttaggc aaatacaatg agggcgaatt
    29041 ggtcggtgcg tggtttacct ttcccattga ctttgaggaa gtcaaagaga aaatcggctt
    29101 gaatgatgaa tatgaggaat acgccattca tgactacgag ttacccttta cggttgacga
    29161 atacacttcc attggcgaac tcaatcgact atgggaaatg gtatcggaat tacccgaaga
    29221 attacaatcg gagctatctg ctctgctcac tcatttttca agcattgaag aactaagcga
    29281 acatcaagag gatattatca ttcattccga ttgtgatgat atgtatgacg tggcacgcta
    29341 ctacattgaa gaaacgggtg ctttaggcga agtaccagct agtcttcaaa actatattga
    29401 ttatcaagcc tatggtcggg atttagacct ttcaggaacg tttatctcaa ccaatcatgg
    29461 gatttttgaa atcgtctatt aaatctgtcg gtacattact actggcagat tttctatttt
    29521 acggggtggc tcaatcagct acccctattt tttatgaaag gattgattac atgaagaaaa
    29581 tacgaagcta taccagtatc tggtctgtgg aaaaggtact gtattctatc aatgatttta
    29641 gacttccgtt tcccataacc tttacgcaaa tgacatggtt tgtcgtgtca ctctttgcag
    29701 tgatgatact tggcaacttg ccccctcttt ccatgataga gggagcattt ctcaaatact
    29761 ttgggattcc tgtggctttc acatggttta tgtctacaaa aacttttgat ggtaaaaagc
    29821 cttatggatt tttgaagtct gtcattgctt atgcactgcg accaaagctg acctatgcag
    29881 gaaaaaaagt aacgcttggc agaaaccagc cacaagaagc cattacagca gttaggagtg
    29941 aattttatgg catatccaat taaatacatt gaaaacaatc tcgtctggaa taaagacggg
    30001 gaatgttatg cttactatga gcttgttcct tacaattact catttctcag tccagaacag
    30061 aaaatacaag tgcatgattc tttcagacag cttatcgcac aaaatcgtga tggcaaaatt
    30121 catgctttac aaatcagtac agaatccagc atacgttctg cacaagagcg ttccaaaaat
    30181 gaagtcactg gcaagctcaa agcggttgcc tatgacaaaa tcgaccaaca gacagacgct
    30241 ttaatatcca tgattggcga aaatcaagtg aactaccgtt tctttatcgg ctttaagttg
    30301 cttctcaacg atcaggagtt ttctatgaaa agtcttaccg ttgaagcaaa aaatgctttg
    30361 tctgattttg tctatgatgt gaaccataag ctgatgggcg attttgttag tatgagtaat
    30421 gatgaaatcc tgcgatttca gaagatggaa aagctcttag aaaataaaat ctctcgtcgt
    30481 ttcaaaatcc gcaggttaga taaggacgac ttcggctatc tgattgaaca cctttacgga
    30541 cagacaggca ctgcctatga agagtatgag taccatctat caaagaaaaa gctggataat
    30601 gaaacgctga ttaaatacta tgacttgatt aagcctactc gctgtttggt ggaagaaaaa
    30661 cagcgatatt tgaaaatcca gcaggaagat gaaaccgtct atgtagctta ctttaccatt
    30721 aacagcattg tcggagaact ggacttcccg tcctctgaaa tcttctacta ccagcaacag
    30781 caatttacat tcccgattga tacgtcaatg aatgtggaaa ttgtagcgaa tcgtaaagcc
    30841 ctatctactg tccgcaataa aaagaaagaa ctgaaagact tggataacca cgcttggcaa
    30901 agtgataatg aaaccagctc caatgtggcg gaagctctgg aaagtgtgaa tgagctggaa
    30961 accaatttag accaaagcaa ggaatctatg tacaagctgt cttatgtggt aagggtatca
    31021 gcaaatgatc ttgacgaact caaacgtcgt tgtaatgaag tgaaagattt ttatgacgat
    31081 ttaagcgtaa aactggtacg accatttggg gatatgctcg gcttacatga agaattttta
    31141 cctgccagca agcgttatat gaatgattat attcaatacg tgacctctga tttcctcgct
    31201 ggtttaggtt ttggtgctac tcaaatgctg ggggaaaatg aggggattta tgttggctac
    31261 agcttagata ctggacgcaa tgtctatctg aaacctgctc ttgccagtca aggggttaag
    31321 ggttcagtaa ccaatgcgtt agcgtcggct tttgttggtt cgctgggtgg tggtaaatcc
    31381 tttgcgaata accttatcgt ctattatgcg gtgctttatg gggcacaagc agtgattgta
    31441 gacccaaaag cagaacgtgg cagatggaaa gaaaccttgc cagagatttc ccatgaaatc
    31501 aatatcgtca ctctgacttc tgatgagaaa aacaaaggct tacttgaccc ttatgtgatt
    31561 atgaaaaatc ccaaagattc tgaatcactg gctattgata ttctgacatt ccttacgggg
    31621 atttcctctc gtgatgggga acgcttccca atccttagaa aagccattcg tgcagtaacc
    31681 aatagtgaag tacgagggtt gatgaaagtg attgaggaat tacgggttga gaatacgcca
    31741 ctaagtacca gtatagccga ccatatcgaa agttttacag actatgactt tgcacattta
    31801 ttattcagta atggttatgt ggagcagtct atcagcttag aaaaacaact gaacattata
    31861 caggttgcgg acttggtact tcccgacaag gaaacttcct ttgaggaata taccactatg
    31921 gagcttttat ccgttgctat gctgattgtc attagtacct ttgctttaga ctttatccat
    31981 acagaccgaa gcattttcaa gattgtagat ttagacgaag catggagctt tttacaggta
    32041 gcacaaggaa aaacactatc tatgaagctg gttcgggctg gtcgtgctat gaacgctggg
    32101 gtatatttcg tgacccaaaa tacagacgac ctcttagatg aaaaactgaa aaataacctc
    32161 ggcttaaaat ttgcatttcg ttccactgac cttaacgaga ttaaaaagac cttagccttt
    32221 tttggtgtag acccagagga cgaaaacaat cagaagcgat tgcgtgattt ggaaaacggg
    32281 caatgcctta tcagtgattt atatggtcgt gtcggtgtga tacagttcca ccctgtattt
    32341 gaagaactgc tccatgcctt tgataccaga ccacctgtgc gaaaagaggt gtaaatgtga
    32401 aaccatcaat agtaaacaga ataaaatcaa actggacgct gaaacgtcta ggtaaagtgg
    32461 caatgacagt ggctttcaca cttgtgattg ccatttttct tttagccatg ctgggaacgg
    32521 tggttcaagc tgcgggcttg gtagatgata cggtcaatgt ggcaaatgaa tacagccgat
    32581 acccacttga aaactatcaa ctggattttt atgtggataa tagctggggc tggcttccgt
    32641 ggaactggtc ggacgggatt ggaaaacagg tcatgtatgg actatatgcc attaccaatt
    32701 ttatttggac aatcagtttg tatgtttcca atgcgacagg ttacttagta caggaagcct
    32761 attccttaga cttcatttcc gctacagcag attccattgg taagaatatg cagaccttag
    32821 ctggtgtgag tgcaaacgga ttttcaacag agggtttcta tgttggattc ctcttactct
    32881 tgattttggt tcttggggtt tatgttgcct atacgggact gataaagaga gaaaccacaa
    32941 aggcaattca tgccattatg aattttgtgc tggtgtttat cctatcggct tcctttattg
    33001 cctacgctcc cgactacatt aaaaaaatca atgacttttc atcagacatc agtaatgcca
    33061 gtttatcact tggcacgaag attgtcatgc cccattccga tagtcaaggc aaggacagcg
    33121 tggacttaat cagagatagc ctgttttcca tacaggttca gcaaccgtgg ctactgcttc
    33181 aatacaacag ttcagacatt gaaagtatcg gtattgaccg tgtggaaagc ctgctctcca
    33241 ccagcccaga ttccaacaat ggcgaagaca gagaaaaaat tgttgcggaa gaaattgaag
    33301 acagaagcaa taccaatcta accattacaa agaccattaa ccgtttaggt acagtcttct
    33361 tcctatttgt cttcaatatt gggatttcca tatttgtatt cctattaaca ggaatcatga
    33421 ttttctcgca ggtacttttt atcatctatg ctatgtttct gcctgtgagc tttattttaa
    33481 gcatgattcc atcatttgat ggtatgtcaa aacgagccat aacaaagctc tttaatacca
    33541 ttttgacacg agctggaatc acattgatta ttacgacagc atttagtatt tcaaccatgc
    33601 tctatacctt atcggctggt tatccgttct ttttgattgc ttttctacag attgtgacct
    33661 ttgcaggaat ctacttcaag ctgggcgatt taatgagtat gttttctcta cagagtaacg
    33721 attctcaaag tgtgggaagt cgtgtgatga gaaaacctcg tatgcttatg cacgctcaca
    33781 tgcaccgtct acagcggaaa cttggacgtt ccatgactac tctaggggct gggtctgcca
    33841 ttgttacagg taaaaaagga cagtcgggtt cggggagttc tgcaaggaca caagcagatc
    33901 actcccgacc agacggaaag gaaaaatcaa cacttggaaa acgtatcggt caaaccatcg
    33961 gtacagtagc tgataccaaa gacagaatgg tagacactgc tagtggtttg aaagaacagg
    34021 ttaaagattt gccgaccaat gcaagatatg cagtatatca aggaaaatcc aaagtaaaag
    34081 agaatgtccg tgatttaacc agtagtattt ctcaaaccaa agcggacaga gccagtggac
    34141 gcaaggaaca gcaggaacaa aggcgaaaaa ccattgcgaa gcgtcgctct gaaatggaac
    34201 aggtcaaaca gaaaaaacag cctgcttctt ctgttcatga aagaccgact acaagacaag
    34261 aacaatatca tgatgaacag acctcaaaac agtctaatat tcagacttca tataaggaat
    34321 ctcaacaagc caaacaagag cgtccagcag ttaagtccga tttttcaagt ccaaaagtgg
    34381 aacgccaagg caataccgtt caagaaaaaa ccgttcaaaa gccagcaact tcaaccacta
    34441 cagcagatag aacttcacaa cgtccaatca caaaagaacg tccgtctact gttcaaagag
    34501 taccactaca aaatacaaga agtagaccac caatcaaaac cgccaccatt aagaaagtcg
    34561 gtaagaaacc atgaagttga aaactttagt gattggtggt tctggattat tcttgatggt
    34621 cttctcactg cttctgtttg ttgccatttt attttcagat gaacaggaca gcggaatttc
    34681 caatattcat tatggaggtg tgaatgtttc cgcagaagtg ctggctcata agcctatggt
    34741 agaaaaatat gccaaagaat atggcgttga agaatatgtc aacatacttc ttgcgattat
    34801 acaggtggaa tcgggcggta ctgcggaaga tgttatgcag tcctcggaat ccctcggtct
    34861 tccacctaat tcattgagta cagaagaatc cattaagcaa ggtgtgaagt atttcagtga
    34921 attattagcc agtagcgaaa ggctcagtgt agatttagaa tcggttatcc agtcctacaa
    34981 ttatggtggt ggtttcttag ggtatgtggc taatcgtgga aataaatata cctttgaact
    35041 ggctcaaagt ttctcaaaag agtattcagg tggcgaaaaa gtgtcttacc ccaatcccat
    35101 agccatacct atcaatgggg gctggcgata caactatggc aatatgtttt atgtgcaact
    35161 ggtaacgcag tatcttgtca caacagagtt tgatgatgat acggtacaag ccatcatgga
    35221 cgaagcactg aaatatgagg gctggcgata cgtttacggt ggagcttccc cgactacttc
    35281 ttttgattgt agcggactga cacaatggac gtatggaaaa gctggaatta acttaccacg
    35341 aaccgcacaa cagcaatatg atgtgaccca gcatatccca ctatcggaag cacaagctgg
    35401 cgatttggtt ttctttcatt ctacctataa cgctggctct tatattactc atgttgggat
    35461 ataccttggc aataaccgta tgtttcatgc aggcgaccca atcggttatg ccgacttaac
    35521 aagcccctac tggcaacagc atttagtggg agcaggacga atcaaacaat gagaaaggaa
    35581 gatttaatga tgaaatttag aaaaaatcag aataaagaaa aacagatacc aaaggaaaag
    35641 aaacctcgtg tctactataa ggtcaatcct cataaaaagg ttgtgattgc cttgtgggta
    35701 cttttagggc ttagtttcag ctttgcgata ttcaagcact ttacagctat agatactcat
    35761 actattcacg aaacaactat catagaaaag gaatacgttg atactcatca tgtagaaaat
    35821 tttgtagaga actttgcgaa agtctactat tcatgggagc aatccgataa gtccattgat
    35881 aatcgaatgg aaagtctaaa aggctatctg acagatgaac ttcaagctct caatgttgat
    35941 acagtacgca aagatattcc tgtatcgtct tctgtaagag gatttcagat atggacggta
    36001 gagccaactg gcgacaatga gtttaatgta acctacagtg tagaccagct cattacagag
    36061 ggagaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt agatggttct
    36121 ggaaatatgg tactggttaa gaatccgacc attaccaaca tacctaagaa atcaagttat
    36181 aaaccaaaag ccattgaaag tgaggggacg gttgattcca ttacaaccaa tgaaatcaat
    36241 gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga actttcctac
    36301 tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca agaactggta
    36361 aatcctattc acaatcgtaa ggataatcaa gtcacggtat cgctgacagt ggagtatatc
    36421 gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga aaagaacggg
    36481 agtaattgga agattataga ataacaaata ttggtacatt attacagcta ttttgtaatc
    36541 acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt atgtgctatt
    36601 atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct taaataaact
    36661 gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc ttagtttttt
    36721 gtacccagtt taaaatacct ttatcatgtg attctaaagt atccggagaa tatctgtatg
    36781 ctttgtatgc ctatggttat gcataaaaat cccagtgata agagtattta tcactgggat
    36841 ttttatgccc ttttgggctt ttgaatggag gaaaatcaca tgaaaattat taatattgga
    36901 gttttagctc atgttgatgc gggaaaaact accttaacag aaagcttatt atataacagt
    36961 ggagcgatta cagaattagg aagcgtggac agaggtacaa cgaaaacgga taatacgctt
    37021 ttagaacgtc agagaggaat tacaattcag acaggaataa cctcttttca gtgggaaaat
    37081 acgaaggtga acatcataga cacgccagga catatggatt tcttagcaga agtatatcgt
    37141 tcattatcag ttttagatgg ggcaattcta ctgatttctg caaaagatgg cgtacaagca
    37201 caaactcgta tattatttca tgcacttagg aaaatgggga ttcccacaat cttttttatc
    37261 aataagattg accaaaatgg aattgattta tcaacggttt atcaggatat taaagagaaa
    37321 ctttctgccg aaattgtaat caaacagaag gtagaactgt atcctaatat gtgtgtgacg
    37381 aactttaccg aatctgaaca atgggatacg gtaatagagg gaaacgatga ccttttagag
    37441 aaatatatgt ccggtaaatc attagaagca ttggaactcg aacaagagga aagcataaga
    37501 tttcagaatt gttctctgtt ccctgtttat cacggaagtg caaaaaacaa tatagggatt
    37561 gataacctta tagaagtgat tacgaataaa ttttattcat caacacatcg aggtcagtct
    37621 gaactttgcg gaaaagtttt caaaattgag tattcggaaa aaagacagcg tcttgcatat
    37681 atacgtcttt atagtggcgt actgcatttg cgagattcgg ttagaatatc ggaaaaggaa
    37741 aaaataaaaa ttacagaaat gtatacttca ataaatggtg aattatgtaa aatcgataag
    37801 gcttattccg gggaaattgt tattttgcag aatgagtttt tgaagttaaa tagtgttctt
    37861 ggagatacaa agctattgcc acagagagag agaattgaaa atcccctccc tctgctgcaa
    37921 acgactgttg aaccgagcaa acctcaacaa agggaaatgt tacttgatgc acttttagaa
    37981 atctccgaca gtgacccgct tctgcgatat tatgtggatt ctgcgacaca tgaaatcata
    38041 ctttctttct tagggaaagt acaaatggaa gtgacttgtg ctctgctgca agaaaagtat
    38101 catgtggaga tagaaataaa agagcctaca gtcatttata tggaaagacc gttaaaaaaa
    38161 gcagagtata ccattcacat cgaagttcca ccgaatcctt tctgggcttc cattggtcta
    38221 tctgtagcac agcttccatt agggagcgga gtacagtatg agagctcggt ttctcttgga
    38281 tacttaaatc aatcgtttca aaatgcagtt atggagggga tacgctatgg ctgtgaacaa
    38341 ggattgtatg gttggaatgt gacggactgt aaaatctgtt ttaagtatgg cttatactat
    38401 agccctgtta gtaccccagc agattttcgg atgcttgctc ctattgtatt ggaacaagtc
    38461 ttaaaaaaag ctggaacaga attgttagag ccatatctta gttttaaaat ttatgcgcca
    38521 caggaatatc tttcacgagc atacaccgat gctcctaaat attgtgcgaa catcgtagac
    38581 actcaattga aaaataatga ggtcattctt agtggagaaa tccctgctcg gtgtattcaa
    38641 gaatatcgta gtgatttaac tttctttaca aatggacgta gtgtttgttt aacagagtta
    38701 aaagggtacc atgttactac cggtgaacct gtttgccagc cccgtcgtcc aaatagtcgg
    38761 atagataaag tacgatatat gttcaataaa ataacttagt gtattttatg ttgttatata
    38821 aatatggttt cttgttaaat aagatgaaat attttttaat aaagatttga attaaagtgt
    38881 aaaggaggag atagttatta taaactacaa gtggatattg tgtcctgtat gtggaaataa
    38941 aacacgatta aagataaggg aagatactga attaaaaaaa ttccccctct attgtccgaa
    39001 atgcagacaa gaaaatttaa ttgaaataaa gcagttcaaa gtaactgtga ttacagagcc
    39061 agacgcaaag acgcagagcc gataaaatga gattaataca atctcatttt atcggctctt
    39121 tccgttatgt atggattctt ttaattagtc ttcgatgttt cttgcttcgt tgataccgct
    39181 ggctaaagat tccattaagg atagttcttt gtctgtaaag ctatccatgt atttctctat
    39241 ctgtaatcgt cgggtgcttt ttaccaagtt attagcaggt aggggtcccg agcgcctacg
    39301 aggaatttgt atcgataaga aatagattta aaaatttcgc tgttattttg tacatttaac
    39361 ttgacggtga catctctcta ttgtgagtta ttagtggtac agttttcaac cgttttaatt
    39421 ataaaaaagt ggtgcatttt taaattggca caaacaggta acggttattg caggtgtatt
    39481 tcttatctat gggtttaaca tggattttat cattaaaatc atgagtattg tccgagagtg
    39541 attggtcttg cgtatggtta accctaaagt tatggaaata agacttagaa gcaaacttaa
    39601 gagtgtgttg attgtgcatt atcttaaaat tttgtataat aggaattgaa gttaaattag
    39661 atgctaaaaa tttgtaatta agaaggaggg attcgtcatg ttggtattcc aaatgcggaa
    39721 tgtagataaa acatctactg ttttgaaaca gactaaaaac agtgattacg cagataaata
    39781 aatacgttag attaattcct accagtgact aatcttatga ctttttaaac agataactaa
    39841 aattacaaac aaatcgttta acttctgtat ttatttatag atgtaatcac ttcaggagtg
    39901 attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca
    39961 accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag
    40021 gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat
    40081 tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaacatt cgtgtcactt
    40141 taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg
    40201 ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg
    40261 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
    40321 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
    40381 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
    40441 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
    40501 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
    40561 aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc
    40621 tattatttaa cgggaggaaa taattctatg agtcgctttt gtaaatttgg aaagttacac
    40681 gttactaaag ggaatgtaga taaattatta ggtatactac tgacagcttc caaggagcta
    40741 aagaggtccc tagcgcctac ggggaatttg tatcgataag gaatagattt aaaaatttcg
    40801 ctgttatttt gtacaataag gataaatttg aatggtacca taaacgaccg tttatggtac
    40861 cttttcattt tcctgctttt tctaaatgtt ttttaagtaa atcaagtacc aaaatccgtt
    40921 cctttttcat agttcctata tagttatact taatgagtta tggtacattt aaattataaa
    40981 attaaggagg tttttttatg atttttggct atgctcgagt gagtacggat gatcaaaatc
    41041 ttagtttaca aattgatgca cttactcatt atggaattga taaattattt caagaaaaag
    41101 taactggtgc gaaaaaagac cgaccgcaat tagaagaaat gatcaaccta ctacgtgaag
    41161 gagattctgt tgtcatttac aagttagatc gaatttcacg atcaactaaa catttgattg
    41221 aactttctga attatttgaa gaacttagtg tcaattttat atctattcaa gataacgtag
    41281 atacttcaac gtctatggga agattctttt tccgagttat ggctagttta gcagaactgg
    41341 aacgggatat tattattgaa cgaactaact ctggtcttaa ggcagccaga gtccgaggaa
    41401 aaaaaggggg ccgtccaagt aaaggtaagc tatcaattga tttagcttta aaaatgtatg
    41461 acagcaaaga gtattctatt cgtcaaattc ttgatgcctc taaattaagc aaaacaacct
    41521 tttaccgtta cctcaataaa aggaatgctt aagatatggc tatgaaaaga attttaacta
    41581 cttcacagcg tgaacaactt ctttctgtag accacttatc agaagaggat tttaaagcgt
    41641 attttagttt ttctgattat gatctggagg ttattaatca acaccgtgga aaggtcaata
    41701 aactaggatt tgcgatacaa ctttgtttgg cccggtatcc tgggtgttct ttaagtaatt
    41761 ggccgattaa atcaaccaga ctaacttctt atgtgagtcg acagctccat cttgatgcaa
    41821 ttgatttaaa ttcatatgat catagaaata cacgtgcaaa tcacttcaac gagatcttag
    41881 aagtattcaa ctatcatcga ttcggtagtg ctaatacaca aaaacagtta atagaatatt
    41941 taattgaact agctttagaa aatgatgact ctatctatct aatgaaaaaa acaattgatt
    42001 tcttaactcg aaaaagaatt atttttccat ctatagctac acttgaagac attataagcc
    42061 gctgtcgaga taaagcagaa aacaacttat tttcaatatt actctgttca ttaacagata
    42121 tacaaattga aaaactagag agtttgtttc aaatttatga agagacgaaa ataactaaac
    42181 tcgcttggct aaaagacatt ccaggtaagg caaatccaga aagctttatg agtatttgta
    42241 aaaaagtgga agtgattgct tccatgggac tcgggacaat taatgtctcc catattaatc
    42301 ggaacaggtt tcttcagcta gctagactag gggaaaatta tgatgcatat gacttctccc
    42361 gttttgagct tgaaaaaaga tactctttac ttattgcttt tttagtcaat catcatcaat
    42421 atctgatcga tcaactgatt gagattaatg accgcatttt agcaagtatt aaacgcaaag
    42481 ggacacgtga ttcacaagaa cagttaaaag aaaaaggaaa attggctact aaaaaattgg
    42541 aacattatgc ttctttaatt gatgctcttc actttgcaaa agataatgat agtaatcctt
    42601 ttgacgaaat tgaacgaatc atgccttggg aagatttagt acaagatgga gaagaagcta
    42661 aaaaaattac aggtaataaa aatcatggct atttagaaat ggttcgaaat aaagctaatt
    42721 acctccgaag atacacgcca atgttattga ggaccctttc gttcaaagca actccggcag
    42781 caaatccagt cctcatggcc ctaactcaac taactgattt acacaatagt ggtaaaagaa
    42841 aaataccggc agatacttct actgattttg tgagtaaaaa atggaaaagc cttgttcggc
    42901 cagaagaggg gaaaatagat cggtcttact atgagttagt agctttcacc gagctaaaga
    42961 acaatattcg atcaggagat atttcagttg aaggaagtat gatccatcga aatattgatg
    43021 attacttagt tgatttatct gcttgtattg attcagaaac tattccagac acgtttgagg
    43081 actatttaaa ggatcgggaa ataattttag atttacagct tcaattttat tcgacagttg
    43141 ataagagaat ttcaagagca aaccttaaaa agttggaaaa agttacacct agcgaagcag
    43201 aaatatatag aaaaaaactt tattcaataa ttcctaagat aaggcttagt gatcttttaa
    43261 ttgaggtgga cagttggacc aacttttcac aagaatttag tcatgattct acagggaaac
    43321 cgccgagtga acaagaaaga aaaattattt ttgctgcttt gctgggttta gggatgaata
    43381 ttggtcttga aaaaatggcc caatcaactc ctggaatttc ttattctcag ttagccaatg
    43441 ccaaacaatg gcgcttttat aaagaagctc tgactcgtgc tcaatctgtt ttggttaatt
    43501 atcagttaaa gcttcctgtt gcagactttt ggggtgaagg aaaaaccact gcttcagacg
    43561 gaatgcgcgt cccagtgggc gtctcagctc taaaatccga tgttaatcca cattacaaaa
    43621 gtatggaaaa aggagctaca atgattcgat caataaatga taggcatacg actcatcata
    43681 tcgaggttgc ttcaactaat acaagggaag ctactcatac ccttgatggc ctactttatc
    43741 atgaaacaga tctagatatt gaggaacatt ttactgatac aaatgggtat tctgatcagg
    43801 tgtttggaat gaccgcatta ctaggctttg attttgaacc tcgcatcaga aatataaaaa
    43861 aatcacaatt attttctatc aaatcacctt cctactaccc taacttatca gaagatataa
    43921 gcggaaaaat caatgtaaaa attattgaag aaaactatga tgaaattaaa cgaatcgcct
    43981 attcgattca aacaggaaaa gtatctagtt ctttactatt aggaaagcta ggctcatacg
    44041 cacgtaagaa tagagtagct cttgcactga gagaactagg tcgcattgaa aagagcattt
    44101 ttatgataga ttatattaca gatagtgagc tacggcgaag gatcactcat ggactaaata
    44161 agacagaagc gattaatgct ttagctagag aactattttt tgggcgacgc ggaaaattta
    44221 tggagcgcga tattcgccga caacttcaaa gtgctagtgc gcttaatgtg ttaataaatg
    44281 caataagtat atggaacgcc gtctacttac aagcagctta taattatctc gtcaaaatag
    44341 atcccgaagt aactaagtat atgaagcatg tatctcctat taattgggag catatcactt
    44401 ttcttggaga gtataaattt gacttgttat ctattcctaa acacttaaga gaattgaata
    44461 taaaaaataa ataggccttg aaacattggt ttagtgggaa tttgtacccc ttatcgatac
    44521 aaattcccac taagcgctcg ggaccccagg taagaaaaat tcatcaacgg aaacatgaag
    44581 taacgataca aggtcataaa gaacttgtat gctggggtgt tgccctttat tttcaatatt
    44641 agttaagtac cgtgggtcaa tttcaatcaa tgctcccact tgttcacgag ttaaacctcg
    44701 tttcaatcga gcttctttaa tggctaaacc aaaggctcta aaatcatatt tatcttcttt
    44761 tttacgcata gtagaccacc tctatacatt ttattgttcc tactgaatta aaaacaggta
    44821 tagaaaaacg tgttatatgg tttataggtt tatatttaat aaaaagcact actaaacgcc
    44881 aataaaaaaa accgttatat ggtagtgcta tttacgctgt taaaatattg tatattactt
    44941 ccaaatggcg gtttgttgga ggtcaacgtc gccatgaagt acatcatata caataaattt
    45001 ccttacattg ggttcttgtc aaaaaaagtc gtctatctgc aatagataag tacgtccacc
    45061 aatgtggttt tataaatcat atagatagaa taacagaagc atgtaaacag agaaataaat
    45121 ctgtttatat gcttttttgg ctattcagaa cttttttaca aagtttattt atcagtaatg
    45181 caacaaatcc ccctttcaca ttgggactaa gagtgaaagg agataaacga gcaaggctca
    45241 cttcctttcc tagacagaaa gggggtgaga aacatgaaac catcttcttt tcagaccaca
    45301 atagaaaatc agtttgacta tatctgtaaa cgtgctatgg aagacgagcg aaagaattat
    45361 atgctttatc tttcaaggat tgcaaagcgt gaggtgtcct tttcggatgt tggcgattat
    45421 cttgttagcc agtttgcgac aacagataac tattcaactg actttcagat ttttacactc
    45481 aatgggttat cagtaggcgt tgaaaatgat ttgttgagtg aagcattacg tgagttgcca
    45541 gacaagaaac gtgaaattct actgctgttt tactttatgg acatgagcga ttcagaaatt
    45601 gcagacctgt tgaaattgaa ccgttctact gtctatcggc atagaaccag tggactagcc
    45661 ttaattaaaa agtttatgga ggaatttgaa gaatgaaaac acaatatcct atgattccct
    45721 ttcctctcat tgtaaaggca acagatggcg ataccgaagc gattaaccag attctacatc
    45781 attacagagg gtacataacg aagcgttccc tacgacttat gaaagatgaa tatggcaatc
    45841 aaagtatggt cgttgatgaa gtcttacgtg gaagaatgga aaccagactg attacaaaga
    45901 ttttgtcatt tgaaattaag taatatcctc tctcctttcg tggaagcgtg ctaaaccatt
    45961 ccacgcttcc cgaacaggga ggtttgttat tccaccaaag catattgagc tttcaatgtg
    46021 ttttgatagg ctaacgagcc attgttcttt gaaaactgaa taaaagtaat cgaatacgtt
    46081 tcgataagaa aagagccaac ggaactaacc gccatgacct atcttataaa gatagcgagc
    46141 gattcatgtt agtgatccga gaagcaatct ttagcaggat tgcctgcaac gacattctta
    46201 tcgtgataat gatactccca tacagtcaat agtccgagcg tgataaaacc gtcgcaggca
    46261 atgagtatgg ctacatgaga accatgcagg ggtggaactc ccgtgagctt tgctaaagct
    46321 gttcgattgc tggtaaaaca acttttatga aatccaaata agtgatttgg aaaggaggat
    46381 tttatgaagc agactgacat tcctatttgg gaacgttata ccctaaccat tgaagaagcg
    46441 tcaaaatatt ttcgtattgg cgaaaacaag ctacgacgct tggcagagga aaataaaaat
    46501 gcaaattggc tgattatgaa tggcaatcgt attcagatta aacgaaaaca atttgaaaaa
    46561 attatagata cattggacgc aatctagcgt cgccaaaggg tcttgtatat gataaaatag
    46621 tattaagtcg tatcaaggct ctttccataa aggaaaggag caaatgccat gtcagaaaaa
    46681 agacgtgaca ataaaggtcg aatcttaaag actggagaga gccaacgaaa agacggaaga
    46741 tacttataca aatatataga ttcatttgga gaaccgcaat ttgtttactc gtggaaactt
    46801 gtggctacag accgagtacc agcaggaaag cgtgattgta tctcacttag agagaaaatc
    46861 gcagagttac agaaagacat tcatgatggt attgatgttg taggaaagaa aatgacactc
    46921 tgccagcttt acgcaaaaca gaacgctcaa agaccaaagg ttagaaaaaa cactgaaact
    46981 ggacgcaaat atcttatgga tattttgaag aaagacaagt taggtgtaag aagtattgac
    47041 agtattaagc catcagacgc taaagaatgg gctattagaa tgagtgaaaa tggttatgct
    47101 tatcaaacca tcaataacta caaacgttct ttaaaggctt cattctatat tgctatacaa
    47161 gatgattgtg ttcggaagaa tccatttgac tttcaactga aagcagttct tgatgatgat
    47221 actgtcccta agaccgtact aacagaagaa caggaagaaa aactgttagc ctttgcaaaa
    47281 gctgataaaa cctacagcaa aaattatgat gaaattctga tactcttaaa aacaggtctt
    47341 cgtatttcag agtttggtgg tttgacactt ccagatttag attttgagaa tcgtcttgtc
    47401 aatatagacc atcagctatt gagagatact gaaattgggt actacattga aacaccaaag
    47461 accaaaagtg gcgaacgtca agttcctatg gttgaagaag cctatcaagc atttaagcga
    47521 gtgttagcga atcgaaagaa tgataagcgt gttgagattg atggatatag tgatttcctc
    47581 tttcttaata gaaagaacta tccaaaagtg gcaagtgatt acaacggcat gatgaaaggt
    47641 cttgttaaga aatacaataa gtataacgag gataaattgc cacacatcac tccacatagt
    47701 ttgcgacata cattctgtac caactatgca aatgcaggaa tgaatccaaa ggcattacag
    47761 tacattatgg gacatgctaa tatagccatg acgctgaact attacgcaca tgcaacattc
    47821 gattctgcaa tggcagaaat gaaacgcttg aataaagaga agcaacagga gcgtcttgtt
    47881 gcttagtagt acaaatgaat ttactactta tttaccactt ctgacagcta agacatgagg
    47941 aaatatgcaa agaaacgtga agtatcttcc tacagtaaaa atactcgaaa gcacatagaa
    48001 taaggcttta cgagcattta agaaaatata aaaagataat tagaaattta tactttgttt
    48061 atttataaaa aaactaaatg aattgatttt aaagaaataa aatgctaaca tatatagtag
    48121 atgttagtat tttatttcta agaaaggaga atgatatggt tgataaaaga gagaaactga
    48181 tgaactcttt caatcagtat ggttttttaa cttttaaaca agtaatagat gaaaatttac
    48241 actacaaaac cttattaaaa atggttgcag aaggaaaaat cgatgctgaa gaaaaagggt
    48301 tatatcgctt acctgatatt tatttagatg agtggtttgt ccttcagtat cgatttccaa
    48361 agggaatctt ttctttggag acagcacttt ggttacatgg tttatctttg actatccctt
    48421 ttaacatgac gatgagtttt ccttatggta cgaataccaa aaacattaag gaagcagata
    48481 tatgtcctat tatcttacgc tctcactata gtgaaggaat tattgaaata gagcgccttc
    48541 ctggtcaatt tattaaagtt tatgaagttg agcgagtttt ggttgaatgt ctaagaccag
    48601 ttcatcaggt ggatcttcaa attattgcac cagcgtttaa aaaatatttt caacaaaata
    48661 aaattcattt acacaaatta ttttattatg cccagctatt taaagtaact gataagttac
    48721 aatcttatac ggaggtacta tcttaatgtt ttcaaatgcg aatagcttta aagcaaaaat
    48781 caaaaacatt tcaaaagata agggaattcc agctcaacaa gtacaacaac attatttaat
    48841 tgagcaagtg ttaaagctga tttctactag ttcttataga gattccttca ttgtaaaagg
    48901 agggtatcta ataggtcaaa tgattggact agataagcga accacaatgg atttagatgt
    48961 cactctgaag ggaaccgaaa tgagcagaga aaatttgatt catatctttg aagagattct
    49021 ttgttctaat actgatggat tttcattttc agtagataag ctagaaccta ttcgtcaaga
    49081 tgatgaatat ggaggatttt cattaaaatt aaatgcaact tttgatacat taaaagaggt
    49141 tgtttttatt gatattacta ctggtgataa aatcacacca agagaaatta cttattcaat
    49201 gacttctatc tttactaatg aaagcatcaa gatatggaca tataatctag agactgtact
    49261 tgctgaaaag ttagaaacaa tcatcagtag gggactagct tcgacgcgtc cacgtgatcg
    49321 atatgatctt ttcaccttgt ataaacttag aaaagaagag attaatcttg aagtattaaa
    49381 aaatgcactt gagaatacgg cagaaaaacg taaaagtaaa gatactattt ataattggga
    49441 agaacaagtg agaggaattg aaatttctga ttatcagaaa gagctatgga ttcgttatca
    49501 acgccaattt aagtatgcta aagatatctc atttgataac tctgttcagg tcattaggga
    49561 aattatgcaa caaatatttt agtacaaaag taactcatta gtaaagcagt gagttgcttt
    49621 ttttattcca ataactccaa aaatgtgata aaaatttcaa ctactcttat ctataataaa
    49681 gctacctgtt ctttgaaaat tgaatccact ccgtcttgat tagcgtgcct gtgtaagtag
    49741 ggactgagag tatttccctg tgaagggcaa ctggcacaag acgtgtgtga gaattttcta
    49801 acagacacgg agtttatcgt taccagactt aaacgatgcg acaaactaga taaaggagtt
    49861 aatcatgaag gtagtaaact tgtatgattt gaaacaaatg ggaaataaag gtggttgtac
    49921 catccaattg attcatcact ttccttttgg tatgggctta ggacatctca aaaaagacta
    49981 cattgaattt aaacgtgttg gtatcgttga tgggaaggca gtagaagtca ctcttcgaga
    50041 accttattcg agagatctac tgcaggttgt caagtcgatt aagcaacgtc agaaattgat
    50101 agcttatcgt tataaagaag gaaagctgct atttgtgaag aaggaggcat cagatgtcct
    50161 ctgaacaaca ggaacgaatg gcagttcaat atgcggagcg tagtctttta tttactgtca
    50221 aaagtctctt aaaaattcta gaatggtcta gacgtcaggc tttagcacag gattccgcct
    50281 ataagatagg ggtgcagaaa ttagaagaat tgctacaatc tccttattcg attgatacga
    50341 ttaatctgaa aaaagatttt ttagacaaac caattgatat agagaaattt aaagcttttt
    50401 tagaaaaaga agagattcct ttagccatcg cttggcaagg ggattctcta catttctaca
    50461 cgaaagaccg ttcgattctg gacaatcatt tagaccatct gttagaaaaa atggttaatg
    50521 atccggagaa attagctgat tttaccatgg ataagtcatt agacgatgca attgatgagg
    50581 cgaaatccca aattaccttt agacaagaag gggccgtcaa acagaaagag atggtgagat
    50641 gatgtacagt ggaaagaaat tcctactatt ttcactgtta ggtatcttac taggctatct
    50701 ttttcatcgt ttgacgcttt tgtatgattc ctatactgga aatacattag ataaatggac
    50761 tcatcttctg atggaaggtc aagatgaagt tcttcagtcg ccatggaatg tttcctttac
    50821 tggaaaatcc agtgcttttt ttctactagg ctttgtgatg atgttgctgg tttatcttta
    50881 tttagagact ggcaaaaaac aataccgaga aggggtagaa tacgggagcg cccgttttgg
    50941 aactctaaaa gaaaagaagc tcttttacgg taaggaattt tctcatgata cgatcttagc
    51001 tcaagatgtt cgtttgacat tattagataa aaaacccccc caatatgata gaaataagaa
    51061 tattgcggtg atcggaggtt caggaagtgg gaagacattt cgctttgtga aacctaatct
    51121 tattcagatg aatagttcta atattgtagt ggatcctaaa gatcacttgg ccgaaaaaac
    51181 aggcaaactc tttttagaac atggctatca agtaaaggtg ctagatttag tcaatatgaa
    51241 gaactcagat ggcttcaatc cttttcgcta tatagagaca gaaaatgatt tgaatcgcat
    51301 gctgacggtt tattttaata acaccaaagg ctctggctcc cgaagtgacc cattttggga
    51361 tgaagcttct atgactttgg ttcgagcttt agcctcttac ttggtcgatt tctataatcc
    51421 acccaaaaca agagaacagc tcattgaaga gagtcgtttg agtcaaaaag aataccagaa
    51481 cttgttgaaa cgtcaaaaaa aagaagtgga agagcgaaaa aaacgaggac gttatccaag
    51541 ttttgctgaa atctcaaaac tcattaaaca cttatctaag ggtgaaaacc aagaaaaaag
    51601 tgtcttagaa attctatttg aaaattatgc taaaaagtat ggcactgaaa attttaccat
    51661 gcgaaattgg gcagatttcc aaaattataa ggataagact ctggattctg ttatagctgt
    51721 aaccactgct aaatttgccc tcttcaatat tcaaagtgtc atggatttga ccaaaagaga
    51781 tacccttgat atgaagacat ggggccagga aaaatcaatg gtttacttag ttatcccaga
    51841 taacgatagt acctttcgct ttctttcagc cctctttttt tcaaccgtat ttcaaaccct
    51901 aacaagacaa gcagatattg attttaaggg tcaattgcct cttcatgtga gagtctactt
    51961 agatgagttc gcaaatatag gagaaatccc agattttgct gaacaaacct caacagtccg
    52021 ttctcgaaat atgagtctcg ttcccattct tcaaaatatt gcccaacttc aagggctcta
    52081 taaagaaaaa gaagcttgga aaaccatttt ggggaactgt gatagcttag tctacttagg
    52141 tgggaatgat gaagatacct ttaaatttat gagtggctta ctcggtaaac aaaccattga
    52201 tgttcgaaat actagtcgtt cctttggcca gacaggttca ggatcccttt ctcatcaaaa
    52261 gattgctcgt gatttaatga cacctgatga ggtcggaaat atgaaacggc atgaatgctt
    52321 ggttcgaatt gccaatatgc ctgtctttaa aagcaaaaaa tacaattcca ctaagcatcc
    52381 aaactggaaa tacctagcca atcaagaaac cgatgaacgg tggtggaact atcaaatcaa
    52441 tcctttgaat caaagacaag aaaatcatct tgaaggcctt agaattcgtg atttaacttt
    52501 tgaatctagt ttaaaataaa aatagaaaag aggaaataga tgattacgca ttttaaaggt
    52561 tttgtttatg gagtagacgc aagtgctatg tttgcacaag ctatgtcttt gttacagaag
    52621 ggtttgattg cggttggtgc ctttctcgtt gttgtgggga ttgtcaatct tgcaaccaac
    52681 attaaagatg gtggaccagg tgttcggaat gccattctgg aaattgtcgg tggtgttatg
    52741 gtaggggctg ctggagcctt tgtaactcaa atttcaattt aggaggataa acaatgacat
    52801 gaatcttagt ttagtctcac cctttgttta ccttgcatct gaaaaaatat cagctgaaaa
    52861 tttatttgaa gggtttaatg tagatttaca atctacggta gatctgatta aatccctatc
    52921 tagctacaat ccaacagttt ggacttatat gtctagtatt actaaaagtg tcatgcagcc
    52981 tcttggagtt gcgattttat cagttgttct catcttagaa ttttcgaaga tggcaaagaa
    53041 aattgctaac tcaggaggag cgatgacctt tgaagcatta gcgccgatgt tgattagtta
    53101 tatcatggtc gcagtcgtga ttaccaatac taccgttatt gtagaagcca tcatcgggat
    53161 tgcgagtcac gccattgaac aagtggcctc aattgtggct cacggtgggg caaagtatga
    53221 taccatctct ggattaaaag gttcaggatt tattggccgg atgattgtgg gctttttcgc
    53281 cctcctcatt tggctagttc ggatagtaag tgcagccatg gttaaccttt tggtatctat
    53341 tcgatttatt caactctacc ttatgattcc atttgcccct cttacgattc caacattttt
    53401 aagtgatgaa tggaagtcta ttggtattgg ctatttaaaa aatattatgg tttatgcggt
    53461 acaaggggtt ctcatttttc tgattgtttc tcttgttcct ttatttgaat ctgctgggaa
    53521 aatagctgtt tcaaatggtg caggagtctt gcaatcactt gcgattatgt ttggtagttt
    53581 ggtacaagct atcttactga ttattgccct cgttggttct caacgtacgg ctcgctcaat
    53641 cttaggtatg taattagata aaggctagga agtgattgct tcttagcctt tttagaaagg
    53701 aaagtcatga atacacgtgt ctttaaagac atctcaaaat accaacacag ggcttggtta
    53761 ggtttcacca caagacaaat catctttgtt ttaccagcct ttattgtcac aattattgtt
    53821 ttgggcttga atctcttttt ctggcaattt ggagattggt ttgtttacgg ttttgtgttt
    53881 gcttttacca tccccctcat gctttttgga gtctataaac ccaatgattt atattttgaa
    53941 cattatttga aataccgtct tcattttgaa ctaacggttc ccctacgcac aattacagga
    54001 aagaaaggac ctgaacatga aaagaaaatc aaatacatta aagaaacaaa aaacttcaat
    54061 gactaatcag aaagaagtag ttaaaggaaa aaaagaggaa gtgttaccat cgacggctaa
    54121 tactctttcc tatcaagccc tgtatcaaaa tggtctgatg caggtaaaag aagattattt
    54181 ctcacaaagc tatttacttg gtgatgtcaa ttaccagact gttggtttag aagataaggg
    54241 cgcaatcatt gagaagtatt ctgatttgat taactcccta gacgaccaaa ccaacttcca
    54301 attgactatc tttaataaaa gattgaattt agaaaagttt agacaaagtg ttttgtatga
    54361 ggaaaaagaa gatgggtatg atagctatcg taaagaattg aatcggatga tgaatcagaa
    54421 tttagacagt ggtgaaaata acttttcagc tgtgaaactg attagctttg gtagaaagga
    54481 ttctaatccc aaacaagcct atcgttcctt gtctcaaatt ggagaatatt tcaagagtgg
    54541 tttctcagaa attgatgctc gatttgaatc tttggctgga gaagaacggg tgaacttgct
    54601 ggcagatatg cttagaggag aacaccatct tcctttttct taccgtgatt taacgagatc
    54661 tggtcagaca actcgtcact tcatagcacc taatctcttg gattttaaaa acaagaatta
    54721 cctacaaatc aatgaccgct tattgcagat tgtctatgtc agagactacg gtatggaatt
    54781 aggagatcag tttatttgag acctcatgca aggagatttg gaattgattg tgagcctcca
    54841 tgctcaaagt tcgaccaagg cggatgctat gaagaaacta cgaacaaaga agaccttgat
    54901 ggaatcccaa aagattgggg aacaacaaaa acttgctcgt acaggtatct atttggaaaa
    54961 agtaggtcat gtattagaaa gcaatatcga tgaagctgag gaactcttaa aaaccatgac
    55021 cgagacagga gataaactat ttcaaacagt attcttgatt ggtgtttttg gtcaggatga
    55081 agaagaactt aaacaagctc tagatacgat tcaacaagtg gccggctcaa atgacctaat
    55141 gattgataaa ctaccatata tgcaagaagc agcctttaat agtttgctgc catttggttg
    55201 tgatttttta gagggagtat cacggagttt attaacatcc aatatagcag tgaactctcc
    55261 atggacttca gtagacttac aagaccgtag tggaaaatat tacggtatca atcaaatctc
    55321 aagcaatatt attaccattg atcgcagcct attaaataca ccgtctggtc tgattttagg
    55381 gacatctgga gctgggaaag ggatggcaac caagcatgaa attatcacga cccaaatcaa
    55441 ggaatctggt gaaaatactg aaattatcat cgtggatcca gaagcagaat acagtgtcat
    55501 tggacgagct tttggtggag aaatgattga tattgcgccc gattcccaaa cttatctcaa
    55561 tgtccttgat ttgtctgagg aaaatatgga tgaagatcct gtaaaggtaa aatcagaatt
    55621 tcttttatcc tttatcggca agttattgga tagaaaaatg gatggaagag aaaaatcgat
    55681 tatcgaccga gtcacaagac tcacctatca gtcatttaaa gagccttctt tggaagaatg
    55741 ggtctttgtc ttgagccaac aaccagaaga agaagcgcag aatttggcac ttgatatgga
    55801 actgtatgtc gaaggttctc ttgatatttt ttctcataag accaatattc agacaggatc
    55861 taatttcttg atttataacg ttaagaagtt aggagatgag ctgaaacaaa tcgcccttat
    55921 ggttgttttt gatcagatat ggaatcgtgt cgttcggaat caaaaattag ggaagaagac
    55981 ctggatttat tttgatgaaa tgcagcttct cttattagat aaatatgcca gtgatttctt
    56041 ctttaaattg tggagtcgtg tcagaaaata tggagccagt ctgactggaa taactcaaaa
    56101 cgtcgaaacc ttattgttag atccaaatgg tagacggatt attgcaaata gtgaatttat
    56161 gattcttctc aagcaagcaa aaaatgaccg agaagaactg gttcaactct taggcttgtc
    56221 aaaagaactc gaaaaatacc tagtcaatcc agaaaaagga gcaggactga taaaagctgg
    56281 ttcagttgtc gtaccattta aaaataagat tcctcaaggt actcaattgt ttgatattat
    56341 gagtacggat cctgataaaa tggcttctaa ttaaggggaa ggtaaatgaa ggataaaaga
    56401 gaaatcatac gtgcccgaaa agcatttaga agaagtctaa aagatgagaa gaaattcttg
    56461 aaacaaggaa agaaggaggt gaggaaacag aaaaaagatt ccgctgtact ggatgaaaaa
    56521 gcatggaaaa aagagataaa agaaaagcta gaggagatga gagaagcttc aaaggagaga
    56581 gtaaaacaag caaatgaaga ctacaatcat attcttcaaa atagtcctcc atcttttttg
    56641 aatcgtaaag aattaagaga cagacgatta cctcatgcta ggaaacgatt gaaaatagcc
    56701 aagaagcaat ttagagaagc caaggtagaa gcaaaagaag aaagaaaaga gagtcgtaaa
    56761 gaaagaaaaa ccaatcaaaa atttctctac ggtcaggaat cgaaacaaaa atctaatttt
    56821 ttctttcaag ggaagagttt agaagaatta aaagctaaga aagaagtcaa ggctgctaaa
    56881 gaaaatttaa aatctactaa acaagcctat aagtacaaaa aagtcagtag gaaagccaaa
    56941 acttttcttt atgtccttgg acgtgaaggt ggagagttag cttcagaaaa tgaagattta
    57001 gaaggctatc gcacacttca agagaccatt agaaaaggga aacgctacag tcggctttct
    57061 tataatcttg gaaaagctag tgtcaaaaca ggacaagcaa caggtcgttt taccaagaaa
    57121 agactgacca acacaaaaga gcgataccat cattttaagg atggaaaagg atggaaacta
    57181 gcaaaagata acccaagttc ctttaagaat cggtttcgaa aattaaagaa acaaggtctt
    57241 tcaagtgtcc aaaatatcta tcaaaaacta aaagcagcct tttccttctt tacatttgcg
    57301 gctggaaatc ctgcaacatg gatagttgga ggaatagtct ttcttctttt acttatgatg
    57361 agcttcttct taggattttc atctgctagt ttgattcaac aagatgaatt tgaattaaca
    57421 aaagcttata cccacctaac ttgggaagat gcagaacata ctcgcacaaa tgacaaagga
    57481 attacctatt acacaaaagt tgatgatgtg atggggtata tgaactttaa attccatgac
    57541 tatgagttac agaaaccagt tcacttattt agttcagaaa cttacaagga ttatctgtct
    57601 actttgtggc atgatttaaa cgatggtgat gatttgaaat ccatgcaaga cctctatgaa
    57661 actcctaagt ataaactatc gaaagacgat caagaggaaa taaaggaact aaaagaagaa
    57721 ggtgtgtatg cttccatgca ggaattagac aatccatttg agggacaaag caacgaagat
    57781 agtctaacca tgacttatcg ttatggatac tatgatttag atgggaaacc tactcttcag
    57841 gagtacatcc tactagaagc aaaggctcac caaacgattg tcgcaccaat ggatgcagtt
    57901 gtatctctag atggtgacaa tattattctc actaacggaa aaggagagaa tgagagtcga
    57961 ttaaccttgt attctattca taatggccgt gcgattgagg ggacaagagt cctaacgggt
    58021 gatattattg gtgaaacacc agacgataca ggtttgaaag tttcctatca aaagtataag
    58081 aacaagaaag aaaaattggt gtatgtcaat ccgcaatttt attttccaaa agtcattcaa
    58141 cttcagacca ctatcttacc tgccattggt cagtttggtg gggatgagtt tgaacgagca
    58201 aaacatattt atgatttttt gaaatctcaa ggcgtaagtc cccaagccat tgcggctatt
    58261 ttaggaaatt ggtctgtaga gtcttctatt aatccaaaac gagctgaagg agattattta
    58321 tctcctccag ttggcgctac cgattcctca tgggatgatg aaagctggtt agcgattgga
    58381 ggtccagcca tttatagtgg tgcttatcct aatattcttc atagaggttt ggggttaggg
    58441 caatggacgg atacttcaga tggttcaaca cgttatacag ctttattgaa ttatgcacat
    58501 agcaaaaata agaagtggta tgatttagac ctccaacttg attttatgct tcatggggat
    58561 agtccttact accaaagttg gttaaaagat ttctttaaaa atacgggcag tgcagccaat
    58621 ctcgcccaac tcttcctcac ctattgggag ggaaattctg gtgacaaatt actggaaaga
    58681 caaaccagag caacggaatg gtattaccaa attgaaaaag gcttcagcca aacaaatgga
    58741 ggacaggcaa aaagtgaccc acaatccctt gaaggggttc gtggggactt gtatgatcat
    58801 tctgttcctg gtggtggaga tggtatggcc tatgcctatg gacaatgtac atggggtgtt
    58861 gcggctcgta tgaatcaatt aggcttaaaa ttaaaaggaa gtaatggaga gaagatttca
    58921 atcattaata ccatgggaaa tggtcaggac tgggttgcga cagcttcaag tcttggtggg
    58981 gaaactggct ctacaccaag agcaggtgct attgtttctt ttgtgggagg tacacatggc
    59041 acaccagcag actatggtca tgtagctttt gt
//
LOCUS       DAVFJR010000007        56207 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVFJR010000007 DAVFJR010000000
VERSION     DAVFJR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.007"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(341..1528)
                     /locus_tag="VU722_000624"
     CDS             complement(341..1528)
                     /locus_tag="VU722_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HEU1771653.1"
                     /translation="MKKIVFASALALTLAGAVLTNDVFANDRLVATQSTDSNVLTSEV
                     LKPSSGNVLVGIKGEFLPPHQQSILDAINKIRKEAADEGLVDKYVPVKWSVDHEKTAF
                     VRAAEVSVTLKAERLSSKNNWTAFPSGNSLSGEALDLNPDGFLKAIENWHAEKANYVA
                     KKKDKTSKEFSFYYENLINPKFTYVGLAAFKNAASPQKAATVALALGTTTSSEELAGG
                     YGSAVQYTEVTASNLSTVKSKAMVVETPLKDFRKSTSDQSGWVQSNGKWYFYESGDVK
                     TGWLKTGGKWYYLNDLGVMQTGFVEVDGSVYYLSNSGAMFTGWGTDGSRWFYCDGSVA
                     MKTGWYKENGTWYYLDEEGIMKTGWFKVGQHWYYANGSGALAVSTTTPDGYRVNANGE
                     WVS"
     gene            complement(1827..2993)
                     /locus_tag="VU722_000625"
     CDS             complement(1827..2993)
                     /locus_tag="VU722_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU1771654.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDC
                     NLLLLQPAASNDAGFAMTSSFMSMMLTALLVFDPIEFAVKSERFEVVSSLARKVLDNA
                     EDVKELVDLDFKRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INEDTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(3291..3683)
                     /locus_tag="VU722_000626"
     CDS             complement(3291..3683)
                     /locus_tag="VU722_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1771655.1"
                     /translation="MTKSLILVSHGRFCEELKGSTGPQDNIYTVALLPEDGPEEFTAK
                     FEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINASLTGA
                     DADYKSRAAESIVKVNDLLADFDDDEDE"
     gene            complement(3690..4505)
                     /locus_tag="VU722_000627"
     CDS             complement(3690..4505)
                     /locus_tag="VU722_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1771656.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(4492..5397)
                     /locus_tag="VU722_000628"
     CDS             complement(4492..5397)
                     /locus_tag="VU722_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU1771657.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(5425..5901)
                     /locus_tag="VU722_000629"
     CDS             complement(5425..5901)
                     /locus_tag="VU722_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU1771658.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(5898..7685)
                     /locus_tag="VU722_000630"
     CDS             complement(5898..7685)
                     /locus_tag="VU722_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU1771659.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPASLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEDDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            8033..8749
                     /locus_tag="VU722_000631"
     CDS             8033..8749
                     /locus_tag="VU722_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1771660.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            9066..13001
                     /gene="strH"
                     /locus_tag="VU722_000632"
     CDS             9066..13001
                     /gene="strH"
                     /locus_tag="VU722_000632"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU1771661.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVNSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESACTVDLGNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAYP
                     LSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRQSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(13056..14354)
                     /gene="purB"
                     /locus_tag="VU722_000633"
     CDS             complement(13056..14354)
                     /gene="purB"
                     /locus_tag="VU722_000633"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU1771662.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(14417..14644)
                     /locus_tag="VU722_000634"
     CDS             complement(14417..14644)
                     /locus_tag="VU722_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU1771663.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(14654..15745)
                     /gene="purK"
                     /locus_tag="VU722_000635"
     CDS             complement(14654..15745)
                     /gene="purK"
                     /locus_tag="VU722_000635"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU1771664.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            complement(15732..16220)
                     /gene="purE"
                     /locus_tag="VU722_000636"
     CDS             complement(15732..16220)
                     /gene="purE"
                     /locus_tag="VU722_000636"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU1771665.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(16623..17885)
                     /gene="purD"
                     /locus_tag="VU722_000637"
     CDS             complement(16623..17885)
                     /gene="purD"
                     /locus_tag="VU722_000637"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU1771666.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(18007..19554)
                     /gene="purH"
                     /locus_tag="VU722_000638"
     CDS             complement(18007..19554)
                     /gene="purH"
                     /locus_tag="VU722_000638"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU1771667.1"
                     /translation="MTKRVLISVSDKVGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYIKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            complement(19579..20088)
                     /locus_tag="VU722_000639"
     CDS             complement(19579..20088)
                     /locus_tag="VU722_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU1771668.1"
                     /translation="MLESKQTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(20172..20717)
                     /gene="purN"
                     /locus_tag="VU722_000640"
     CDS             complement(20172..20717)
                     /gene="purN"
                     /locus_tag="VU722_000640"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU1771669.1"
                     /translation="MKKIAVFASDNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(20714..21736)
                     /locus_tag="VU722_000641"
     CDS             complement(20714..21736)
                     /locus_tag="VU722_000641"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU1771670.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(21773..23215)
                     /locus_tag="VU722_000642"
     CDS             complement(21773..23215)
                     /locus_tag="VU722_000642"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU1771671.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(23308..27033)
                     /locus_tag="VU722_000643"
     CDS             complement(23308..27033)
                     /locus_tag="VU722_000643"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU1771672.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(27235..27942)
                     /locus_tag="VU722_000644"
     CDS             complement(27235..27942)
                     /locus_tag="VU722_000644"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU1771673.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            complement(28112..29461)
                     /locus_tag="VU722_000645"
     CDS             complement(28112..29461)
                     /locus_tag="VU722_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU1771674.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(29474..31627)
                     /locus_tag="VU722_000646"
     CDS             complement(29474..31627)
                     /locus_tag="VU722_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU1771675.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(32007..32498)
                     /locus_tag="VU722_000647"
     CDS             complement(32007..32498)
                     /locus_tag="VU722_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771676.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(32479..33075)
                     /locus_tag="VU722_000648"
     CDS             complement(32479..33075)
                     /locus_tag="VU722_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1771677.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(33072..33554)
                     /locus_tag="VU722_000649"
     CDS             complement(33072..33554)
                     /locus_tag="VU722_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU1771678.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(34698..34994)
                     /locus_tag="VU722_000650"
     CDS             complement(34698..34994)
                     /locus_tag="VU722_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU1771679.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(35537..36430)
                     /locus_tag="VU722_000651"
     CDS             complement(35537..36430)
                     /locus_tag="VU722_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1771680.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKDSLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNVAEAESFYEKAISLAEL
                     LDDQVLVQKILAEKQIDFPTT"
     gene            complement(37184..37414)
                     /gene="blpU"
                     /locus_tag="VU722_000652"
     CDS             complement(37184..37414)
                     /gene="blpU"
                     /locus_tag="VU722_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU1771681.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(37617..37907)
                     /locus_tag="VU722_000653"
                     /pseudo
     CDS             complement(37617..37907)
                     /locus_tag="VU722_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(37953..38186)
                     /locus_tag="VU722_000654"
     CDS             complement(37953..38186)
                     /locus_tag="VU722_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU1771682.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(38192..39184)
                     /gene="plsX"
                     /locus_tag="VU722_000655"
     CDS             complement(38192..39184)
                     /gene="plsX"
                     /locus_tag="VU722_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU1771683.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(39181..39951)
                     /gene="recO"
                     /locus_tag="VU722_000656"
     CDS             complement(39181..39951)
                     /gene="recO"
                     /locus_tag="VU722_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU1771684.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(39948..41117)
                     /locus_tag="VU722_000657"
     CDS             complement(39948..41117)
                     /locus_tag="VU722_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1771685.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            41266..42276
                     /locus_tag="VU722_000658"
     CDS             41266..42276
                     /locus_tag="VU722_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU1771686.1"
                     /translation="MSFLSKNGAGIFVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(42389..42469)
                     /locus_tag="VU722_000659"
                     /pseudo
     CDS             complement(42389..42469)
                     /locus_tag="VU722_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(42504..42941)
                     /locus_tag="VU722_000660"
     CDS             complement(42504..42941)
                     /locus_tag="VU722_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU1771687.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(43026..45659)
                     /gene="polA"
                     /locus_tag="VU722_000661"
     CDS             complement(43026..45659)
                     /gene="polA"
                     /locus_tag="VU722_000661"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU1771688.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDY
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYGGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(46162..46383)
                     /locus_tag="VU722_000662"
     CDS             complement(46162..46383)
                     /locus_tag="VU722_000662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771689.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGIEQGREEGLEEGLKVGL
                     VNLVRQGLLTPEVASEQLGMTVAEFESLL"
     gene            complement(46376..46492)
                     /locus_tag="VU722_000663"
     CDS             complement(46376..46492)
                     /locus_tag="VU722_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU1771690.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(46707..47060)
                     /locus_tag="VU722_000664"
     CDS             complement(46707..47060)
                     /locus_tag="VU722_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU1771691.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(47178..48146)
                     /locus_tag="VU722_000665"
     CDS             complement(47178..48146)
                     /locus_tag="VU722_000665"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU1771692.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(48291..49106)
                     /locus_tag="VU722_000666"
     CDS             complement(48291..49106)
                     /locus_tag="VU722_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU1771693.1"
                     /translation="MKKNSILFIFILLLCIGLQYETIYYTDGSISGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKNALILSLLGGMFLSGWLSSFANTYIHDLLGGLFPD
                     SAFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGTASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKIGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(49131..49628)
                     /locus_tag="VU722_000667"
     CDS             complement(49131..49628)
                     /locus_tag="VU722_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU1771694.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENGPF
                     QEYLKEELGVDMSDQDFLPFQDIEESVREDMKLLIESSLIPDDVIISGAIYDVDTGSM
                     TVVEL"
     gene            complement(49701..51065)
                     /gene="radA"
                     /locus_tag="VU722_000668"
     CDS             complement(49701..51065)
                     /gene="radA"
                     /locus_tag="VU722_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU1771695.1"
                     /translation="MIAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEIEVAEVK
                     NARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGK
                     STLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEV
                     ERIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE
                     GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLN
                     PSQVFLEERLDGATGSSIVVTMEGMRSILAEVQALVTPTMFGNAKRTTTGLDFNRASL
                     IMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVG
                     ELGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITPPKEIQVIGVTTIQEVLK
                     KVFA"
     gene            complement(51076..51591)
                     /locus_tag="VU722_000669"
     CDS             complement(51076..51591)
                     /locus_tag="VU722_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1771696.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSDMGRQQVQKLSK
                     NPLLSSAEIIVSSAVARALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENRGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(51593..52036)
                     /locus_tag="VU722_000670"
     CDS             complement(51593..52036)
                     /locus_tag="VU722_000670"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU1771697.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(52093..52190)
                     /gene="ffs"
                     /locus_tag="VU722_000671"
     ncRNA           complement(52093..52190)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VU722_000671"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(52223..52690)
                     /locus_tag="VU722_000672"
     CDS             complement(52223..52690)
                     /locus_tag="VU722_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU1771698.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCILFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(52891..54177)
                     /locus_tag="VU722_000673"
     CDS             complement(52891..54177)
                     /locus_tag="VU722_000673"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU1771699.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKEIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(54408..54644)
                     /locus_tag="VU722_000674"
     CDS             complement(54408..54644)
                     /locus_tag="VU722_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU1771700.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            54910..55721
                     /locus_tag="VU722_000675"
                     /pseudo
     CDS             54910..55721
                     /locus_tag="VU722_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55756..55965)
                     /locus_tag="VU722_000676"
                     /pseudo
     CDS             complement(55756..55965)
                     /locus_tag="VU722_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(56131..56204)
                     /locus_tag="VU722_000677"
     tRNA            complement(56131..56204)
                     /locus_tag="VU722_000677"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56168..56170),aa:Asn,seq:gtt)
BASE COUNT        17143 a        13034 c        10059 g        15971 t
ORIGIN      
        1 ataaatcgat agaaatttct attgaaatat acttaaaaat atactgcaat tttttataga
       61 agaatacaat gaactgcaac aatagaaaac ggaaacaaaa tctagacaaa taagtgagga
      121 gtttcaaact aattacagta ttttttaatt agattaccga ttatgctttt aatatactat
      181 aaaatattag ctcataatag aaaagtctga gattgaagcg acaaagaatc caatctttat
      241 aaaccaaaag aggtcaatgt ctgccatcaa cctctttctt atatttcatt ctttttgcta
      301 agtaagatga atactttacc tatgacttgc tcttttcagc ctagcttacc cattcaccat
      361 tagcatttac acggtaacca tctggtgttg ttgtgctaac agccaaagcg cctgaaccat
      421 ttgcatagta ccagtgttga cctactttaa accaacccgt cttcatgatc ccttcttcat
      481 caaggtaata ccatgtacca ttttccttgt accagcctgt tttcatagct actgagccat
      541 cacagtagaa ccatctgcta ccatctgttc cccagcctgt aaacatagcg cctgagttac
      601 ttagataata caccgatcca tcaacttcta caaatccagt ctgcataaca cctaggtcat
      661 tcaagtagta ccatttacca cctgttttca accagcctgt cttcacatca ccagactcat
      721 aaaaatacca cttgccatta gactgcaccc agccagactg atcagacgta gattttctga
      781 aatctttcaa cggtgtttct acaaccattg ctttactttt aactgttgaa aggtttgagg
      841 cagtcacttc tgtgtactga acagcagaac catatccacc agccaattcc tctgaagaag
      901 tcgtagttcc tagagccaaa gcaacggttg ctgccttctg aggactagct gcatttttaa
      961 aagcagcaag acccacatag gtaaatttag ggttaatcaa gttctcataa taaaatgaaa
     1021 attcttttga tgttttatct ttctttttcg ccacatagtt cgccttttca gcatgccaat
     1081 tctcaatggc ttttagaaat ccatcaggat tcaaatctag ggcttctcca cttaggctat
     1141 taccagatgg aaatgcagtc cagttgtttt tactggaaag acgttcagcc ttcaacgtaa
     1201 cggatacctc agcagcgcgt acaaaagccg ttttctcatg gtcaactgac catttgacag
     1261 gaacatactt atctaccaaa ccttcgtcag ctgcttcttt acgaatttta ttaatggcat
     1321 ctaaaataga ttgttgatga ggaggcaaaa attctccttt gattccaacc aaaacattgc
     1381 cactagaagg ttttagcacc tctgaggtca atacattact atcagtagat tgtgttgcaa
     1441 ccagtctgtc attcgcaaaa acatcatttg tcaaaactgc tcctgccaag gtcaaggcca
     1501 aggcgctagc aaatacaatt ttcttcattt ctttcttact ccttattgta gtttgaatat
     1561 tatcttaaca gatacctttt ctctcaatca aacaaaccat agaaagcgaa ttgacaatct
     1621 atggtttgcc tgatgatgta caaatcctct tgtcaagaat tcataaacac tgtcttatac
     1681 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgctcaaa gcactgtttt
     1741 gaggttgtag atagaactga cgaagtcagt aaccatacct acggcaaggc gacactagta
     1801 tggtttaaag agattttcga agaatattac ttttgatatt cgtggatgat aacaccttgt
     1861 accacacggt ttacggtacc tgtaggagac ggtgtatctg gtttattttc taccttgagt
     1921 gaagtcaata gagcaaagag ttgagcatat acgatgtatg ggaagacacg gtaaatatca
     1981 ttcaagacac cgccacaacc aagggccact tctttgacat tttcaagacc aaaggcttga
     2041 tcactcaaaa gcacaacacg acgagcaatc tggtcaccag caacttcacg aaccaagtct
     2101 aagtcgtact tgcgagtgta gtctgtcgtt gtaccaaaga ccaagacaac tgtatcttcg
     2161 ttgataagtg attttggacc gtgacggaag ccaactggac tttcatacat agtcgcaact
     2221 tgaccagctg ttaattccaa aatcttgagc tgagcttcat gagcaagccc aaagaaagga
     2281 ccagcgccta ggtagatgac acgcttaaag tctaggtcaa caagctcttt gacatcttct
     2341 gcattgtcta gaactttacg ggcaagacta gaaacaactt caaaacgttc agatttcaca
     2401 gcaaattcta taggatcaaa gaccaagaga gctgtcaaca tcatagacat aaagctagaa
     2461 gtcatggcaa atccagcgtc attagaagca gctggttgca agagcaagag attacagtca
     2521 tcaccgtgag cttgaagagc caatttacca tctgctgcac aagtaatcgt cacttgataa
     2581 agctcatcca ccaaggattt ggccaaatca acagtcgcca cactttcagg cgagttccca
     2641 ctacgagcaa aagacacaag gacagttgcc acatcttttt tcaaataggt tgctggattg
     2701 gcaacgatat ctgttgttgc aatggcattg aaattccatt tgcgttcgtc atagacttcc
     2761 ttaaagtaag gtagcaaggt atctcccaca taagcagaag tcccagcacc tgtcaagata
     2821 accttaatat agtcatgttt atcagcgatt tcttgtagga aggctgcaat ttcttcacgt
     2881 tttgcttgat aaaattcaaa agcttctctc catacatcag gttgttggta gatttcacgc
     2941 gtagtgattt ctgcacccaa ttcgagcaag tcttcttttg tataatgtag cattgagttc
     3001 ctctttttct attaaatatg ggaatgggag taagctccat tcccatgtat attctatata
     3061 aaatgctcta acgattttca cgttgtcaca tgaattgaat cgagttccaa ctaaaatctg
     3121 taggaaacta gccgcaggct gctcaaagca ctgctttgag gttgccggat aagactgacg
     3181 aagtcagctc aaaacaccgt tttgaggttg cagatagaac tgacgaagtc agtaacatat
     3241 acctacggca aggcgacgtt gacgtagttt gaagagattt tcgaagagta ttattcatct
     3301 tcatcatcat caaaatccgc taacaggtca ttaactttca caatgctttc tgcagcacgg
     3361 ctcttgtagt ccgcatctgc gcctgtaagg ctcgcattga taaattcaat caccattgga
     3421 agattcatcc ctgcgtaaag gtcaatatca cgaccttcca tgatcaagcg actcaccaca
     3481 ttacaaggtg tcccaccgag aagatccgca aagactagga aatcatccaa cccttcaata
     3541 acagcttcaa atttagcagt aaattcttct gggccatctt ctggaagaag agctactgtg
     3601 taaatgttgt cttgtgggcc tgtgctacct ttaagctcct cacagaagcg accatggctc
     3661 accaaaatta atgatttagt cataaggaat tacattccaa gtgcaaagtg accaagggca
     3721 gaaagagcca aagcaagtac gataataata ccgatagctt tagtagagtt catacctttt
     3781 ttaccaagca accagaagat aaaggcagta aagattgctg gaagcaaacg tgggaagatt
     3841 tggttcaaga tgtcttggaa atcaatcatc ttttcaccga ttggcaactt gtaagaaatt
     3901 tcaaagttaa tcactgttgc tacaagagca cccatcatga agacaccaag tacagatgca
     3961 gcgtcaatca aagctgtcaa ggtactttgc atgttgttga taaggttaac cccttctttg
     4021 taagcaaatt ccaactgttt ccaacggaag atgtcatacg ctactgcaac tgcaatccaa
     4081 aggaagatcc cccaaggttg gccagcgata gccatagttg ctgcgactga ccccatgata
     4141 gcaggtacaa gtgaaccaaa gattgtatcc ccaagaggag cgaatggtcc catcaaacct
     4201 gtcttgatac cgttaacagc gtcttttgaa cctacaccat ctttttcttc catggcaagg
     4261 tcaaaaccag cgataatggt atggaagaat ggtgaagtat tgaagaattg agtatgaact
     4321 ttcatcattt ctttcaattc aggagttcca tcaccataca ttttacgcaa ctgaggcaag
     4381 atcatgtaaa ggtaaccaga agcttgcata cgttcgtagt tccaacctaa ttggaaagta
     4441 aacaagctac gtttgttgat ttgattaaaa tcttcttttg taagtttgta attagaattc
     4501 gtcatcttcg atttccccac tttctgatgg tgtagaaggt gctgctacag ctactttttg
     4561 gctatttttg aagtgaagca ctgcaaggaa aatacctacg atagaaatac caatcataga
     4621 caaacctttg aagttgttca cgaaaccaat tttttcagca acttcagcag gaagagtacc
     4681 tacgatacca gcaacagcgc caccaagacc tgttacatat gagtaaagaa cagtcaacat
     4741 agctgtcaaa ccaaatccca tagcaaggta gtgaaggtta cgtttaactg gaaggtaacg
     4801 aagcaagatt gcaaatccaa gacctggaag catacgtcct gcgagtgtca agccatctgc
     4861 aacccatttg taggcttcaa caaagtctac tactgattgt acaaaggcac caccaaaagc
     4921 aagggcaaag aagactggaa gggcacgaga tagagcccac ggaatcgcac caagcaagta
     4981 gttgcgttca atacctttat agtcaaagcg ttcgattgca gcatccacac ggtgagcgaa
     5041 gaaggtagta gtcatacgac caagaacgtc gaagtaagtc aagagagctg ctactggtac
     5101 agcgattgta gtaattgcaa gcggtgcatc aattccttgt gaaacagaga aggctgtcgc
     5161 aagaaccgca ccagaagttg cgtcgatacg agaagcacca ccgaaggtac caaccccaag
     5221 aacgaacagt tgcaagttac caccgataag taaaccagta gtcacatctc ccatgattaa
     5281 accagtaatg aaaccagcaa atacagggga acctgcagat gaaacgatcg tcaactcatc
     5341 acagatttga taagctgagt acaaagtgag aagtaaaatt tgccaccatt gtatcataac
     5401 aatgacctcc taaaaatttt tttcctattt taataagctc aaaaagtctg aaattggatc
     5461 atttggaacc atctgagcag taagtttaac acctttttct gccagtttgt ggaagtcttc
     5521 cacatccttg tctactacgt tgatagaacg tgtaatagaa cgagtttctg gtgtttgaga
     5581 catattccca acattaagag tttcaagtgg tacacctgct tctaccaaac caaggaagcg
     5641 gtccggttta cgagccacga taaagagacg ttggctatcg tatttgccag caagaatatt
     5701 ggctgcagct ttctcaactg gcaaaatact caatttcaca cctggtggtg tcgcaagttt
     5761 caaaccactc ttttcaatat cgttgttgac aacttcgtcg tctacaacca taatgcgtga
     5821 aacatttagt tttccagccc aaagattggc tacttgtccg tggatcaaac gtccatcaat
     5881 acggcatcct acaattgtca taagttttcc ccctttatat gttttagtgt aggtttacga
     5941 gttaaatgaa tctcttcttt atattgacct tctgtttcaa agataatgat gcggttggca
     6001 ccttccttga gatagcaatg agggatataa agtgagagag ttgggccaac gttccaaaaa
     6061 cgtcctagat tctgcccatt gacaaaggca actcccttac caaactcaga caagtctagg
     6121 taagtatctt ttggctcttc gactgtaaag tcataagcgt aaaaggctgg ttgtccttga
     6181 gtccatcctt ttgaaaaatc aattttctca ggattgtcta gtgggagtgg atagtgtttc
     6241 cagtttagta agaaatgcag atccttacag acccctgtcc gaattccctt acgttgcgta
     6301 tccgctaaga acttatgccc atagttgaca cgccccatat tttctatcaa gatatctaac
     6361 ctagatagcc ctttcttttt accttgataa aaaatatctt ccccaatctc tgtctgatat
     6421 tgagttttaa cccactgacc atcgacatac agctgagccc tatctcgacc atcaatgata
     6481 cgaagtcttt cttcttctgc atcccagttt gtttctgttc gataaagtag gtagccataa
     6541 ctttgtccca gctcctccat cttttgagga tagagacttt ctacaggact tgacaagcta
     6601 tctaaggttt caaacaaaga aactttttca actagtggaa tagcatccaa ctccatactc
     6661 tctttgtaga gtggttccaa ctgcggatac tctgaaaaat gtgttgccat catcttcttg
     6721 actgcaagat atttagcagt tggatttcct tcttcatcca gaagggcatc gtaatcataa
     6781 gacgtaactt gtggcaggtc caaagttcct cgagctgagc aaccattcat gaaaccaaag
     6841 tttgtaccac cgtggaacat gtaaagattg atagagcctt gttccaaaac ctctcgaact
     6901 gcatctgcca attccttagg atcccgtgtg ataatcggtt ctttccagcg attaaaccaa
     6961 ccatcccaga actccataca catgagtggc catttcttcc catgttcatc aaagaattcc
     7021 tgcatctgtg aaaagttgta aggtgcctta gaaccaaagt tccctgttac aaagagatca
     7081 tcttctatta aggttccagc tttcagagtt gctctccatg gaccatctga tgtaaagagt
     7141 ggacaggtta cgccacgctc ttccatcaac tgtcgaatcg ctctcaggta agccttatct
     7201 tctccgtaag aaccatactc attttcaacc tgcatcatga gaatattgcc accattgtcc
     7261 aacaaacgag gcaccagtct tggcaataac tgatcatagt agcgaccaac tgcctcgata
     7321 tatgctgggt cggatgagcg aattcgcatg ttcttggtca agagcgaagc tggtaagcca
     7381 ccgaattccc attccgcaca gataaatgga gacggacgca caattgcgta gagacccaaa
     7441 tcctgcgcta tttggagaaa tttctctaaa tccagatcac cttcaaaatg aaactcacct
     7501 tcacgaggct cgtgtaaatt ccaagcaaca taagtctcta ccgtattaaa accaagagcc
     7561 ttcaagttat agagcgaatg ataccaatcc tctggaggaa ccctaaaata atgaatggca
     7621 ccagataaaa tcttaaatga ttttccatcg agatagaaat catctcgtat ctcaaatcgt
     7681 gtcataaaac taccttccga ccgcgaaagt ttgcgctttc atttgttgtt atattaatta
     7741 taaaccaatc tgtttgaatt gtcaatagaa attgtcggga tatttactgc atttttacta
     7801 ttatacacac attcaattag tttcaaacat ttttagaccc atttcaaacg ctctttaaat
     7861 tcggaatata ggacctaaaa taattttgta tagaatacat tgataaaata tgagcaatcc
     7921 ctatatcgct taatttttca aactattatt ctaatttttt attcaaaaga ctactatttt
     7981 tttcgctttt atggtaaaat tttctatgga gaaggaaaat agaggtaaaa atatggcaat
     8041 tcccaaatat caatacataa aagacgaatt aaaaaataaa atcatctctg ggcagtttag
     8101 cagtggagat aaattttaca ctgaagcaga actcatttca atgtacgatg tcagctctat
     8161 cacagttgtt cgcgccttaa acgaccttgc caaagatggc tatattgtcc gccaacaagg
     8221 aaaaggaacc ttcgtttcac gtgcacgcaa acacaagctt gtagagtttt cagatattga
     8281 actcttcaat gctaaagatg ataaggtaac tgttctttca attgaacgcg gaaacaagct
     8341 tgtttacttg gaaaaattgg gtctacgcgg cgatcaattc tactacaaga ttgaacgtat
     8401 ccgcgaatca aacggtgtcg tttatatcta ccatacatcc tacatcccag aacaatatat
     8461 caatgcaaat tatccaaacc ttgaatacta tagttctatc tataatcgtt tcaagttaga
     8521 ctaccacatt cacatgaatg atgaacactt tgaagaaatc aacgaaatag tctttccaac
     8581 tccagaacat gcggcttcag tcctcggagt cgatgaacaa ttccctactg tcctacaaac
     8641 taaaatcacc aaactcgaat caactggcca agttttagaa tacagtgaaa cttacaaacg
     8701 atctgattac tacaagatta aattcatctc atgtgaccgt gatcactaag aagaaagcct
     8761 gagcctaatc gctcgggctt tttctatgct tattatacca caccaaaaag gtagcgctta
     8821 cttatttttg gaagattcta taatttgtgg aatattttat agaaatagaa ccaaaaatta
     8881 tattagatat atatatgcat ttttttccga ccaatctgaa atcttaagtt taaattttat
     8941 atttttttat acttattata gttttttgtc atctcctctt gactctcgtt aatataagaa
     9001 ataaaataag ggcgttgatt tatataatcg ctatcaatat aacaatgcaa tcaggaggtt
     9061 ttgcaatgaa acatgaaaaa caacagcgtt tttctattcg taaatacgct gtaggagcag
     9121 cttctgttct aattggattt gccttccaag cacagactgt tgcagccgat ggagttacta
     9181 ctactacaga aaaccaaccg accatccata cagtttctga ttcccctcaa tcatccgaaa
     9241 atcggactga ggaaacacct aaagcagagc ttcaaccaga agctccaaaa actgtagaaa
     9301 cagaaactcc agctactgat aaggtagcta gtcttccaaa aacagaagaa aaaccacaag
     9361 aggaagttag ttcaactcct agtgataaag cagaggtggt aactccaact tctgctgaaa
     9421 aagaaactgc taataaaaag gcagaagaag ctagccctaa aaaggaagaa gcgaaagagg
     9481 ttaattctaa agagtcaaat acagacaaga ctgacaagga taaaccagct aaaaaagatg
     9541 aagcgaaagc agaggctgac aaaccggaaa cagaggcagg aaaggaacgt gctgcaactg
     9601 taaatgaaaa actagcgaaa aagaaaattg tttctattga tgctggacgt aaatatttct
     9661 caccagaaca gctcaaggaa atcatcgata aagcgaaaca ttatggctac actgatttac
     9721 acctattagt cggaaatgat ggactccgtt tcatgttgga cgatatgagc atcacagcta
     9781 acggcaagac ctatgccagt gacgatgtca aacgcgccat tgaaaaaggt acaaatgatt
     9841 attacaacga tccaaacggc aatcacttaa cagaaagtca aatgacagat ctgattaact
     9901 atgcaaaaga taaaggtatc ggtctcattc cgacagtaaa tagtcctggt cacatggatg
     9961 cgattctcaa tgccatgaaa gaattgggaa tccaaaaccc taactttagc tattttggga
    10021 aggaatcagc ctgtactgtc gatcttggca acgaacaagc tgtcgctttt acaaaagccc
    10081 ttatcgacaa gtatgctgct tatttcgcga aaaagactga aatcttcaac atcggacttg
    10141 atgaatatgc caatgatgcg acagatgcta aaggttggag tgtgcttcaa gctgataaat
    10201 actatccaaa cgaaggctac cctgtaaaag gctatgaaaa atttattgcc tacgccaatg
    10261 acctcgctcg tattgtaaaa tcgcacggtc tcaaaccaat ggcctttaac gacggtatct
    10321 actacaatag cgacacaagc tttggtagtt ttgacaaaga catcatcgtt tctatgtgga
    10381 ctggtggttg gggaggctac gatgtcgctt cttctaaact actagctgaa aaaggtcacc
    10441 aaatccttaa taccaatgat gcttggtact acgttcttgg acgaaacgct gatggccaag
    10501 gctggtacaa tctcgatcag gggctcaatg gtattaaaaa cacaccaatc acttctgtac
    10561 caaaaacaga aggagctgat atcccaatca tcggtggtat ggtagctgct tgggctgaca
    10621 ctccatctgc acgttattca ccatcacgcc tcttcaaact catgcgtcat tttgcaaatg
    10681 ccaacgctga atacttcgca gctgattatg aatctgcaga gcaagcactt aacgaggtac
    10741 caaaagacct gaaccgttat actgcagaaa gcgtcacggc cgtaaaagaa gctgaaaaag
    10801 ctattcgctc tctcgatagc aaccttagcc gtgcccaaca agatacgatt gatcaagcca
    10861 ttgctaaact tcaagaaact gtcaacaact tgaccctcac gcctgaagct caaaaagaag
    10921 aagaagctaa acgtgaggtt gaaaaacttg ccaaaaacaa ggtaatctca atcgatgctg
    10981 gacgcaaata ctttactctg aaccagctca aacgcatcgt agacaaggcc agtgagctcg
    11041 gatattctga tgtccatctc cttctaggaa atgacggact tcgctttcta ctcaatgata
    11101 tgaccattac tgccaacgga aaaacctatg ctagtgatga cgttaaaaaa gctattatcg
    11161 aaggaactaa agcttactac gacgatccaa acggtactgc actaacacag gcagaagtga
    11221 cagagctaat tgaatacgct aaatctaagg acattggtct catcccagct attaacagtc
    11281 caggtcacat ggatgctatg ctggttgcca tggaaaaatt aggtattaaa aatcctcaag
    11341 cccactttga taaagtttca aaaacaacta tggacttgaa aaacgaagaa gcgatgaact
    11401 ttgtaaaagc cctcatcggt aaatacatgg acttctttgc aggtaaaaca aagattttca
    11461 actttggtac tgacgaatac gccaacgatg cgactagtgc ccaaggctgg tactacctca
    11521 agtggtatca actctatggc aaatttgccg aatatgccaa caccctcgca gctatggcca
    11581 aagaaagagg gcttcaacca atggccttca acgatggctt ctactatgaa gacaaggacg
    11641 atgttcagtt tgacaaagat gtcttgattt cttactggtc taaaggctgg tggggataca
    11701 acctcgcatc acctcaatac ctagcaagca agggttataa gttcttgaat accaacggtg
    11761 actggtatta tgttataggc aatcacaaac aagatgaagc ttaccctctt tcaaaagcag
    11821 ttgaaaattc tggtaaagtt ccattcaatc aactagcttc taccaaatat cctgaagtag
    11881 atcttccaac agtcggaagt atgctttcaa tctgggcaga tagacaaagc gctgagtaca
    11941 aggaagagga aatctttgaa ctcatgactg cctttgcaga ccacaacaaa gactacttcc
    12001 gtgctaatta taatgctctc cgcgaagaat tagctaaaat tcctacaaac ttagaaggat
    12061 atagtaaaga aagtcttgag gcccttgacg cagctaaaac agctctaaat tacaacctca
    12121 accgtaataa acaagctgag cttgacacac ttgtagccaa cctaaaagcc gctcttcaag
    12181 gcctcaaacc agctgcaact cattcaggaa gcctagatga aaatgaagtg gctgccaatg
    12241 ttgaaaccag accagaactc atcacaagaa ctgaagaaat tccatttgaa gttatcaaga
    12301 aagaaaatcc taacctccca gctggtcagg aaaatattat cacagcagga gtcaaaggtg
    12361 aacgaactca ttacatctct gtactcactg aaaatggaaa aacaacagaa acagtccttg
    12421 atagccaggt aaccaaagaa gttataaacc aagtggttga agttggcgct cctgtaactc
    12481 acaagggtga tgaaagtggt cttgcaccaa ctactgaggt aaaacctaga ctggatatcc
    12541 aaaaagaaga aattccattt accacagtga ctcgtgaaaa tccactctta ctcaaaggaa
    12601 aaacacaagt cattactaag ggcgtcaatg gacatcgtag caacttctac tctgtgagca
    12661 cttctgccga tggtaaggaa gtgaaaacac ttgtaaatag tgtcgtagca caggaagccg
    12721 ttactcaaat agtcgaagtc ggaactatgg taacacatgt aggcgatgaa aacggacaag
    12781 ccgctattgc tgaagaaaaa ccaaaactag aaatcccaag ccaaccagct ccatcaactg
    12841 ctcctgctga ggaaagcaaa gctcttcctc aagatccagc tcctgtggta acagagaaaa
    12901 aacttcctga aacaggaact cacgattctg caggactagt agtcgcagga ctcatgtcca
    12961 cactagcagc ctatggactc actaaaagaa aagaagacta agtcttttcg ataaaaaata
    13021 aacagcgaga ttgaagctcg ctgtttattt tttaattaat cacctagtcc aagacgttca
    13081 aagatatcat ccactcgttt ggtgtaataa actgggttga agatttcatc gatttcttct
    13141 tgagtgagac gtgatgttac ttctgaatct gcctcaagaa gtggtttaaa gtctacttgg
    13201 ttgtcccaag agtaggctgt ttttggttgc accaagtcat aggcttgctc acgggtcatg
    13261 cctttttcaa tcaatgtcaa catagcccgt tggctaaaga taagaccaaa agtcgagttc
    13321 atgtttcgga tcatattttc tgggaagact gtcaagttct tgacgatatt tccaaaacgg
    13381 ttgagcatgt agtcaatcaa aatggtcgta tctggtgtga tgatacgctc agctgatgag
    13441 tgagaaatat cgcgttcgtg ccagagagcg acgttttcat aagccgtaat catgtgacca
    13501 cgaatgacac gcgccagacc agtcatattt tcagaaccga ttgggttgcg tttgtgaggc
    13561 attgctgaag accctttttg ccctttagca aagaactctt ctacttcgcg ttgctcagat
    13621 ttttgtagac cacgaatctc agtcgccata cgttcgattg aagtcgcaat gctggcaaga
    13681 accgcaaagt actcagcgtg aaggtcacga ggaaggactt gtgtagagat ttcttgggca
    13741 cggatgccaa gtttatcgca gacatactcc tctacaaatg gtgggatatt ggcaaagttc
    13801 ccaaccgcac cagaaatctt accagcttct acaccagcag ctgcatgctc gaaacgctcg
    13861 atattgcgtt tcatttcgct gtaccaagtt gccaatttaa gaccaaaggt tgtcggctca
    13921 gcgtgcacac catgagtacg ccccatcatg atggtgaact tgtgctcctt ggccttgtca
    13981 gcgatgatat tagtgaagtt ttcaaggtca cgacggatga tgtcgttggc ctgcttgtag
    14041 aggtaaccat aagcagtatc caccacgtcg gtagaagtta acccatagtg aacccacttg
    14101 cgctcttcac caagagtctc agaaaccgca cgcgtgaaag ccaccacatc gtggcgcgtc
    14161 tcctgctcaa tttccaaaat acggtcgatg tcaaagtccg ccttcttgcg aatcaaagcc
    14221 acatcttcct tagggatttc ccccaactca gcccatgcct cgtcagagag gatttccacc
    14281 tcaagccaag cacggtattt attttcttca ctccaaatat tcgccatctc agggcgagag
    14341 taacggttga tcatgtgtta atttttcctt tcttcttaag ctgttgggaa taagctatct
    14401 aggtaaacca agatttctac tcaaactcct ctttttcaat aaacacagac gggtaatgat
    14461 ctagtgtatt caaatccgta tccagcggta catcatagat agctaaataa ttttcggggt
    14521 attgtgcagc tagttcttca tatttagctt gtaccttatc ttggtcagca ctggcataca
    14581 acacttcaac aactgctcca gtcttatcct tttcaataaa tgtattaacg ataatttgta
    14641 tcatagactt gtcctaaaaa tcaatccctt ccccaaactc ttccacacta tccggcacat
    14701 cactaaacaa agtcacatgt cccatcttac gattatgctt tgcttctatt ttaccataca
    14761 tgtggaggtg ggcgcttgaa ttttctgtca catattgctc agcagcctcg acatgctgac
    14821 cgaggacatt aagcataacg gctggcgcat ggagtttgat gactggtaat ggtgctccga
    14881 gaacacccag aatatgggtg tcaaactgag agaaatcaca ggcttcaata gaatagtgcc
    14941 cagagttatg tggtcgtggg gcgatttcat tgacaataac gtcatcatca gtcgcaaaca
    15001 tttccacaca gagagttcca gacaagttga gttgttctgc gattcgcact gccatagctt
    15061 tagccttgtc tgctagactt tcagaaatgc gggctggtac gatggtctta gacaggatat
    15121 tgttgcggtg gatattttcc tgaactggga aaaacgtcac ctccttgcca tttcctgaca
    15181 cgatgacaga aatctcaagg tcaaagttga caaattcttc caagacgcag tctgctgagt
    15241 ctgctagcgc ataggctgct tccaagtctg cttctgaacg aataaccttt tgtccatgac
    15301 catcgtagcc accagtcgca gtcttgagga catagttttt cgacaagtcg atatctgcca
    15361 agtctaggct agaagtcacg accttgtagg gtgccacagt gacttgagcc ttgtttgaca
    15421 aaaagtcctt ttcaaaaata cgattttgcg aaatgcggag cagatctgtt ccttgaggga
    15481 gttgtccatc cttgataacg gcatccaaac cgtcagcgtc gacattttca aactcgtaag
    15541 tgaggacatc gcaacggtct gccaactgac ggagggcgtc cacatcgtta taaggtgcca
    15601 caatgatttc cgccacgcga gaggccgggc aatccgccgc aggatccagc gcgataacct
    15661 tgtggcccat gtagatagca gaaatggcca tcatctgacc cagttgaccg ccaccgataa
    15721 ttccgattgt tttagatgag ctcatttgac gactcctctg cgatttttcc ttgttcttca
    15781 gcaaagttgg caagtgcatc cgcaatggac ttatcttcta cagagaggag acggagggca
    15841 aagagagctg cgttagtcgc tccagcttca ccgatagcca tggtcgcaac aggcacccca
    15901 cccggcatct gaacgataga atagagtgaa tccactccac taagagcacg agacttgact
    15961 ggcacaccaa tgactggaag ggttgttttg gcagctacca tgcctggcaa atgcgctgcg
    16021 ccaccagcac ctgcgatgat gatcttgatg ccacgactac gggcttcttc tgcatgtttg
    16081 aacatgaggt ctggtgtacg gtgtgcggaa acaactttct tttcgtaggc tacaccgaag
    16141 cggtctagga cttctgctgt tttttgcatg gttgcccagt cggattttga gcccatgatg
    16201 atggaaatta ctggtttcat ttcttctcct ttttcctctt tttcaacaat caccttagct
    16261 tgtgagggac ggcagcagcc accaaaggtg tctcatgcct aaattggaaa cccaaggtct
    16321 tccaatttcc ctgaacgatt ggattatcat ccaatcgttc tttcacaacg gcggtgattg
    16381 ttctatatta gctcgctaac gatcgcaaac catacgatca ttaacgtatt ttgtgaattt
    16441 ttatttttct ttttgataat ggtcttaggt gatggaggcg gaagcaaacc ttcggtttca
    16501 ttcctaaact ttgagcctaa ggtctccaag tttccccctg accagaacat tcactgttct
    16561 ggtcttttca ccacgacgac cattatcgtg tttggcgact acggcgcgtt attcttatat
    16621 ctttacttaa ttgccttgct tccgatatct gttcggtaga agagtccttc tattttttgt
    16681 tgggatagtt cttggtagat gctggcttgg gcttctttga cggtatctgc tgtggtaacg
    16741 agcatataaa ctcgtccgcc gtttgagagc agtgctctgc tattttccgc aaacttagcc
    16801 cctgcatagt aggtgatgac atcgccttct gtctttgctg gcaactcaac gcccctttca
    16861 tagtctagcg ggtagccctt ggatgcgaca accacaccca gagtcacacc cttgtccgtc
    16921 cacatgatat ttggctcctt gctatccagg atatctgtga tattttgagc aaagtcagag
    16981 gtcaagcgag gcaagataat ctgagtttct ggatctccga accgagcgtt gaactcaatg
    17041 actttcggtc catcagctgt caggataagc cctgcgtaaa gaactcccag ataagggcga
    17101 ccttctttaa tcatcccttc tagaactggc ttgacaatgg tgtcaaccgc tgtatcaact
    17161 acactctgtg gtaagtgtgg aactggcgca taggcaccca taccacccgt gttaggccct
    17221 ttgtcgccat cgtaggcacg tttgtggtcc tgagccgttg gcatgatgta gaacttatca
    17281 ccattgacaa aggcaaagag tgaaaattcc tctccttcaa ggaattcctc aataaccacg
    17341 cgcgcacctg agtcaccaaa tttattgtcc aaaagcatct catgagcggc ttcgaccgct
    17401 tgctcaaccg tctcagcaac gacgacaccc ttcccaagcg ccaagccatc cgccttgact
    17461 acgataggcg caccatgctt ttcgatatag gccttggctt cctcgaaatc tgaaaatgtg
    17521 ccataggctg ctgtcgaaac accatatttg accatgattt ccttggcaaa atccttggac
    17581 cactccagct ccgctgcagc cctagtcgga ccaaaggcct taagcccagc ttggttaaaa
    17641 tcatccacga taccagcagc aagggcatca tctggaccga taaaggtcca agcaacatca
    17701 ttggtctttg cgaagtcaat caatttagaa tgttcggaaa tagagatatt taccaattcc
    17761 aaaccatcca gagtcatccc atcattccca ggagctacaa agactttttc cacgtctttt
    17821 gattcaagta actttttagc aatcgcatgc tcacgaccac cagaaccgac aacaagcagt
    17881 ttcattcctc aacctctttt gcgaattatt taccaacatt atatcaaaaa agttcgtttt
    17941 aatcttgttt cagttagcat tttaagccaa aaaaggaaag aaactgtttt cttccctttt
    18001 atcttcttaa tgtctaaaat gtctcacacc tgtaaagacc atagtcaagc cgtatttatt
    18061 cgctgcttcg atggattctt ggtcacggac agagccaccg ggctggatga tggccttaat
    18121 tcctgctttg gcgatttctt ccacgttatc cgcaaatggg aagaaggcat ctgaagcaag
    18181 gaccgccccg tccagacgat ctttggcttg gtcaatggca aggcgaacag aagccacacg
    18241 gttggtttga cctggaccaa caccaagtgt catgtggtcg ttggtcacga taataccatt
    18301 tgatttgatg tacttgatag ccttccaagc gaactcaaga gcagtcgctt ctgtctcagt
    18361 tggctgacgt ttggtcacca cttgccagtc agctgggctt tccttgacca cgtcttgatt
    18421 ttgcacgaga agtccaccga ctacacctgt gtattctgct tccacttcgc tagcctcttg
    18481 agcattaaat ggcaaggcaa ggatacgcaa gtttttcttt ttattgatca aaatagctag
    18541 cgcttcatcc gtatagcttg gtgcaatgat gatttcgagg aaaacgccgt gcatcttctc
    18601 agctgtcgca gcatccacct cacggttgag gacgacaatc ccaccaaaga tagatactgg
    18661 gtcagactca taagcgtagt cccaagcagt ctcgatgtca tcagcttgac caattccaca
    18721 tggattcatg tgtttgagag ccacaacggt tggactatct ttgaagtcac ggatgatacg
    18781 gatagcagca tctgcatcac ggatattatt aaatgacaat tctttcccgt tgagctgttt
    18841 ggctgaagca atagagtaat ctgtaggcaa agctttctgg taaaagtccg cgtcttgttg
    18901 aggattctca ccgtaacgca ttggttgctt gaggtcataa gtcaaagtga gtttttcagg
    18961 cttgctttca cccacttgag ctgtgaagta ttctgcaatc aaggcgtcat aagccgctgt
    19021 gtgacgaaat actttggctg ctaaacgttg gcgagtttca taagaggttt cgccgtttgc
    19081 tgccaattcg tccaaaacca cagcgtagtc agcaggatct accacaactg taacactggc
    19141 atgatttttc gctgctgaac gaagcataga cggcccacca atatcgatat tttcaactgc
    19201 atcagcataa gtcacatctg gtttaaggat agtttcctta aatgggtaaa ggttgaccac
    19261 cacaaggtca atgagctcaa tcttgttgtc cttagccgct tccaagtggc tatccaagtc
    19321 acgacgagcg agaagccctc cgtggatatt tgggtggagg gtcttcacac gaccgtccat
    19381 catttctggg aaaccagtca catcatcgat agcaatggta tccaccccag cattatcaag
    19441 ggcaacctta gttccacctg ttgagataat ctcccaacca agttttttga gttcttgggc
    19501 aaattcaaca atgcccactt tgtctgagac gctgattaag acgcgtttag tcattatatt
    19561 ctccttttta atcattagtt aaacaccaat taaatgcagt aacagtaaaa caagataagc
    19621 aaaaccaagg ctaagcatac ctaagatatt gatccatttt ctagtctgtg atttgaacac
    19681 tcttataaaa atttgataaa tcagtaagcc tacacagaca cctagcgtat ttaaagtcaa
    19741 atccgttata tctgttatac ctattgctaa aatatactgt aaacactcaa acaataaact
    19801 aatcaagaaa cctgtcccga ctattcttaa actagataaa ttagttttta tcaaagggaa
    19861 acaaacacct aatggaataa aggaaatcag attaaataac atttcagcaa aaacaatttt
    19921 tccatcgact attagtggtt ctgaaaatgg aatccaattg atataccttg gagctaagaa
    19981 aaatgctata aattcaggat ttgtttcaaa cttaaataag attccccaag ttaataacat
    20041 cagatagaca taaaatacat atcgagttgt ttgtttagat tctaacatta caaatacctc
    20101 cgtttgaagc cgtcttcaac aaacactgac tccaatttaa aatcaaagat atcatatgaa
    20161 tcatcaaaaa gtcaatctgt aaatagagcc ttcactactt ccggatacaa cctgtactct
    20221 gcttcatgta tgcgagcttc aaatctgtca atggtatcat cagctagtcg tggcacacga
    20281 acctgtttga tgacctggcc tgtatccaca cccgaatcca cccagtgaat ggtcacacca
    20341 gactgaccca cgccagcatt ccaagcatcc tcaatcccat gagctcctgg aaattctggc
    20401 aagtaggctg gatgaatgtt gacaatccga ccttcataag ccgacaataa ggttggtcca
    20461 acgattttca tgtagcctgc taggcaaacc aagtcaatct ggtgttcttc caagagttcg
    20521 acaagggctg cttcgtagtc tgccttgctc tcaaactcct tgagttcaaa agcataggac
    20581 agaacgccga gctgctttgc acgctcaagc acataggcat cacgatggtc tgaaaagaca
    20641 aactccactg gaaattcttc ggcaatcacc tgaaaatttg agccattatc agaggcaaaa
    20701 accgctattt ttttcatttg ataatgacac tttcgttttc tttcttgacg atgcgaccaa
    20761 tttcatagac tgcttcatcc aacaattctt ttacacgctc tacattttca gggctgaccg
    20821 ccaacataag tcccacaccc atattgaaga tttcaaacat ttcttcgtgt ttaatctgac
    20881 catatttttc aagggctttg aaaattggaa gcactggaac tttgctttca tcaatttcag
    20941 cagctaggtc atctgcaaac atacgaggga cattttcgat aaagccacca cctgtgatgt
    21001 gggcaatgcc gttgaccaac tcttctttga tgagcggcaa gacagccttg acatagatac
    21061 gagtcggctc aagtagaact tccttaagtt tcttgccttc caattctggt aggacttcct
    21121 cacctgtgta atccgcaaag acacgacgaa ccaaagagta accatttgag tgaatcccac
    21181 ttgaagcaag tccgagaaga acatctccct ctaccacctt tgaaccgtca atgatttgag
    21241 atttttcagc cacaccgacc gcaaaaccag ccaagtcata gtcgtcttcg ccgtacatgc
    21301 ccggcatttc agccgtttcc ccaccgatga gggcagcacc agcctgcaca caaccttctg
    21361 ccacaccagc aaccacttgt tctagcttag ctggttcatt cttccctgtc gctacgtagt
    21421 cgagaaaata gaggggttcc gcacctgcag caatgatgtc gttgacacac atggccacac
    21481 agtcctgccc gatggtatcg tgcttgtcgt acttgatagc caacatgagc ttggttccga
    21541 caccgtcagt ccctgaaatc aagacgggtt ctttaacccc agtcttggaa aggtcaaaca
    21601 taccaccaaa gccaccaaga gctcccatga cacctgcacg ctccgtacgg gccacgtgct
    21661 ttttaatccg ttcaacaact tcataacccg cttcaacatc cacacccgac tgggcatatg
    21721 catttttatt tgtcatttgt tttttccttt tctttaatgg agaatctgtc gcctacttgt
    21781 aaaaactggt cttttcttcc aaacttctac gatagtcttc ttcgtagtca tagagaggcg
    21841 ttgggtagtc accgtcaaag taagcgacac agagaccacc gttcggcgca tctgtttcga
    21901 taccaatcga ctcaatcaag ctatcaattg aaagataagt cagactgtcc gcaccaatga
    21961 tttggcgagt ttcttcgacc gtatgattgg ctgcaatcag ctcctgacgg gtctggatat
    22021 caatcccgta gaaacatgga tacgctagtg caggacttcc aatggcaacg tgaacctcag
    22081 tcgcacccgc ttctttcaag agctgaacga tacgacgaga ggttgttcca cgtacaatgg
    22141 aatcatccac catgaccaca cgtttgcctt tgacaacacc cgaaacagca gacagtttca
    22201 tccgcactcc ttgctcccgc aattcttgag tcggttggat aaaagttcgc tgggtgtatt
    22261 ggtttttgat cagacccatt tcatttggta agcctgattc ttccgcaaat cccatagccg
    22321 cgcttaggga agaattgggc acaccaacta caatatctgc ctcatgctta aattctcgcg
    22381 ccaattgcgc tcccattctc ttacgtgccg tatggacatt gacaccgtgg atattagaat
    22441 cagggcgggc aaagtagata tactccatag aacaaatcgc caactgggta tcatctgtat
    22501 agctgtcata ctgaatgccc tcgtcatcaa tgatcacaat ctcacctggc ttcaaatcac
    22561 aaatccactc ggcaccaatg acctcaaaag cacaggtttc agaggaaaca accaccgctc
    22621 cgttggccat tttcccgata gaaagcggac gaaagccatt agggtcaaga gccgcaatca
    22681 acttgtcctc aaacagcaag atataggcaa aaccaccttt gacaaggctg agcgcttcct
    22741 tgattttgcc catcaggcta ggattatgac tgcgacgaat gaggtgagcc aagatttcag
    22801 agtccgaagt cgcgctgaaa attgctcctc tttgttccag ttctttcttg agagaggctg
    22861 cattggtcag atttccatta tgagccaaac caaactgcat atcgtgaaaa cggaagagga
    22921 agggttggat gttatcaaca gaagcttcgc cagcagtcgc ataacgcaca tgcccaatcg
    22981 caccagctcc tgtcaattta tccaaattag ctggatttct gaaaacttct gataaaagcc
    23041 ccatgtcacg atggcgcttc agttgtcctt gatcattgga gaggattcct gccccctcct
    23101 gaccacggtg ttgaagactg tggagtccaa aataggtcaa cttagcagca tctggatgtc
    23161 cccaaatacc gaaaacacca cattcttcat taagagattt tacttcgtat gtcatttttt
    23221 atacctaatt ttcatttgta atcatcaaga gctagattta catgactttt acattactga
    23281 tactatctat tagaaaatct gtaagtctta ttttccagtg aaatgtttaa ccgctgatgc
    23341 gaacaggtgt tggtctttat tgcctgggat attttggaaa agaccatcct cataacgttc
    23401 tgagtggccc atcttaccga tgatttgacc attcttgctg gtaattcctt cgatggcatg
    23461 gacagaacca ttcggattgt acttagaatc catacttggt ttaccgttaa agtcaacgta
    23521 ttggctgaaa atttgtccat tgtcacggag ctctgcaaat tcctcagccg tcacgacaaa
    23581 cttcccttca ccgtgcgaaa caggaatagc gtggatatcg cccacttgca caccagccaa
    23641 ccatggtgag ttggtattgg caatgcgagt ttccaccatc ttggccacgt gttggttggc
    23701 atcattgtag aagagggttg ggctagtact gttagcagct tcaaagtttc cgtagggtag
    23761 gagacccgat ttgactaagg cttggaatcc attacaaata ccgataatca aaccaccacg
    23821 ggcgataaag ctatcaatag ccacacacac tttttcatta agcaggatat tgacgataaa
    23881 cttagctgaa ccatctggtt catccgcagc cgagaatcca ccagcaaaga agagaatatt
    23941 agtcttgtcg atattgtcaa ccatagtttc aactgacttg acaatagctt cttcattcaa
    24001 ggtcacgaat ggcaccaaat tgacctctgc accttctttt tcgaaggcct tagctgaatc
    24061 atattctgag ttggttcctg gaaagactgg gatgtaaacc acaggttttt caaccttttc
    24121 tttggcttta atcacaacat ctgatgccac agctggtact tcttctagtt ctttcgcttg
    24181 ggtaaattct gttgggtaaa cttcttccaa tgtcccttga aatgcactgt caagcttgtg
    24241 tccatctagc ttcacaccgt tgacagtcag tgtaaagtct gctttcgttt gtccaacctt
    24301 ctctactcca gcaatttctt caggagatgt gaagacaaag ccgcctaatt gagctgtcaa
    24361 agctgtttta agttcaggca aggtcacctc tgcaccaata tagtttccaa aggtagcaag
    24421 agccaaactt tcaactacac caccgtattt gacagctgat gcagatgtca ctttatggtc
    24481 agcttggatg gcttcaaact gagtaaaatt tttcttaatc aagtcaaaat caatctctgc
    24541 agagagggct tgacctggga tgtagtagat attttcccca acagctttaa attctggaga
    24601 gagcacctta cggctatctg ccgtcgtcac cccaaaggca accaaggttg gcggaacggt
    24661 caattcttca aaggtaccag acatggagtc cttaccaccg atagatggca agccaagctg
    24721 aatttgtgct tcaatagaac ctagaagagc agctactggc tgaccgaaac gctctgcttg
    24781 tttatccata cgctcgaaat actcttggta agagaaacga gccttggacc agttggcacc
    24841 agcagccacc aaacgagcag ttgcttcgat aaccgcataa gcagcaccgt ggtatggaga
    24901 ccattcagct acatatgggt tgaaaccttg agcaatgacc gacgcagtat gagtcacacc
    24961 gtgttgaact ggcaatttct gcacagatgc ctcagttggt gtgagttggt aacgaccacc
    25021 aagtgggtga ttaaccgttg agcgtccaac agagcagtca aagatagtct gtaatccttt
    25081 ttgacttgca tggttgaggt cagatagaac cgtaagggta tctgattcca gtgtttcagc
    25141 agatgtttga cgctcttctg ggagtttgac atccttgtcc acaactttgg catcgacaac
    25201 cacgcgcaca ccattggtgt caaggaaacg acgctccaag tcaacgattg tctcaccatt
    25261 ccagtgcatg acaagatttg gtttttcagt tactgtcgcc accacaacag catcaatatt
    25321 ttctttgtta cattcggcaa cgaaggtatc cacatcttca ggacgaacca cgaccgccat
    25381 ccgttcttgt gattcagaga tggcaatttc tgtaccattc aagccctggt atttaagagg
    25441 caccttgttg aggtcgattt caagaccgtc tgccaattca ccgatagcca cacagacgcc
    25501 gcctgcccca aagtcattgg acttcttgat cagacgagtg acattgccat tacggaagag
    25561 gcgctgaatc ttgcgttctt cgatggcatt tcctttttga acctcagcac cagcagtctc
    25621 tacagactca actgtttgaa ccttagaaga gcccgtcgca ccaccgacac catcacgacc
    25681 tgttttgcct ccgagaagga tgatcacatc acctgcttca ggtttttcac ggacaacatt
    25741 gcccttggga gccgcaccaa caacggcacc aagttccata cgtttagcta caaagcctgg
    25801 gtggaagtat tcacgaacgt aggttgtggc aagcccaatc tggttaccat atgaagaata
    25861 accatgagct gctgttttag aaatgacttg ttgtggcaat ttcccagcac gagtttccga
    25921 aatcggtgct gtaatatcac cagcacctga aatacgcatg gcttggtaaa cataggaacg
    25981 gcctgacaac ggatcacgaa tagctccacc gatacaggta gccgctccac caaatggctc
    26041 aatttctgtt ggatggttgt gggtttcatt tttaaacatg aggagccaag gttccttgac
    26101 accatcaaca tccacttcaa tttcaactga gcaggcattg atttcgtcag agacttccat
    26161 atcatccaat cgtccattag cacgctcata acgaccgaaa atagtcgcca tatccatcaa
    26221 ggtttgtggt ttttcagacc gacctaactc ctcgcgcatg gcaatatact tgtcataggt
    26281 tgactgcaat tgcttttgaa atttagaagc tgaaaagtcg atgtgtttca actctgtctc
    26341 aaaagtcgta tgacggcagt ggtcagacca gtaagtgtcc aaaaccttga gttcagtctc
    26401 agttggcacg cgcccgattg acttaaagta gtcttggata aagagcaaat catccacttc
    26461 catggccatc ccttgctcgg ccttgtagcg agcaaagtct tctgctgtat agctttcaaa
    26521 gaaagtcaat tttggaatgg tcttgtctga ctctgaaaac tcctgcttgg caatccctgt
    26581 cgtgatatcc ttgaaacgag aatcaactgg attgagcagg tagtttttga cagcttccaa
    26641 ctcagtcgca tcaatatctt tattcaccaa gtaaagttgg gctgtgttga ctgtcacgtc
    26701 actcgaactt cccaacaaaa gcaaggcttc ctgtgacgaa gctgcacgct ggtcaaactg
    26761 ccctggcaga ctttcaatgg caaagaaagc atagttagca agatccgcct gcacagatac
    26821 ttcatctaaa acatggtcgg ttccctgctc agagaaaatg tgcttctctg caggtgcaaa
    26881 caagtcctca gccaagtcaa atacatcata tacttgcaca atacgaatac ttttcaagct
    26941 tgacagtccc aagttgtgct ggagctctct aaccaaactc tctgacttga cctgaaaatc
    27001 agcctttttt tcaacaaaaa tacgtttatc catcaattct tattccttta tttcagctct
    27061 tgcaatattc ccaaacagcc ttgaggttgt tattttaaac cctgcaactt ttcccagaca
    27121 atttcgtaaa catctgttag ttcacctagt tctctacaga gtgaaaaggt ctgggggacc
    27181 ttttcagcct gagtcctttt agttgagaga cgaaggtttt ccgttgcaaa cagattattt
    27241 caattcctgc aacttttccc aaacaatctc ataaacgtcg gttagttctc ccaatcctct
    27301 acggaaaaca tccttatcca tgtggttgcc atcagcgtcc cacaagcggc agttatctgg
    27361 tgaaaattcg tctgccaaga taatcttgcc atccttgtca aaaccgaact ctagcttaaa
    27421 gtcaatcaat ttaagcccaa tctcagcaaa ccagactttc aatagttcat tgatacgacg
    27481 cgtttcttcc ttcaagtagg caatctgctg gtcacccgca atctgtagga atttcacatg
    27541 ctcatcattg ataaatggat catccaaatc atcatttttg tagtaaaatt cgacaatcgg
    27601 agtctccaag gcgattccct catccacacc aaaacgtttt gaaaaggaac cagcagtata
    27661 gttgcggagc acgacttcca aaggaataat cttaaccttt ttattgagtt gttccgtgtc
    27721 tgaaagtttc tccacaaagt gagtcgccac accagccgca tttaatttct caaaaataaa
    27781 agatgagatc tgattattca agactccctt acctgcaatc tgctccttct tgacaccgtt
    27841 gaaagcagtc gcctggtcct tgtaagttga aataataaga ttttcatcct cagttgtata
    27901 gatatcttta gcttttcccg aatagatcaa ttgttttgac attttaaagt tcgcctttcg
    27961 tattacttga gcacatttta ccacaaaaaa ccaaaaaaca caagaattta accgaataaa
    28021 tagcatatgt ttttcaaaaa ttgtaaagaa aaaactgcaa gaagaatctt tctcacagtt
    28081 taaaaattat ttaactctaa aaacacgaac attactcttt gttcaaaaat tgatccaaat
    28141 aataacgtag ataacttttc ttgcccgtaa tcatctgcaa gcggccttcc accccgtacc
    28201 taagtttttc agcctgctcc gaagttagat tagtctccgc ctcgatttta aagaaattcc
    28261 ctttctcagt cttagtagct gtcgcatcaa tacttgtaat agtagaatct agaaaaaatt
    28321 gattcccggc atcatgagtc gtagtatagc gaacagaatc accgaccttg attcttgcta
    28381 catcttttga acttagatag gctgtgagtt tggctttccc ttctctttcc aaagatggat
    28441 aaagttgggc tagtagggca ccttctgcaa ccatgctaga atcactggtc tcaggattaa
    28501 gatgaagcac cccatcctca ctcgccgtaa ttttcccctt gtctaaaaga tttccctgta
    28561 ccttcttacc tgactctgcc tccaagattt tctgggctag aagggtcaat tcctgaccaa
    28621 cctttgccaa gtgttgggat ttaagggatt ccaattgact gcttaaccct gacgcatagg
    28681 cttgctgggt acctgaacct gcatactgga cacggtaagt agcaagacta gattctaact
    28741 gagaaatctg tgcttcaacc tgtgcaactg cctgaacctt agtttgggga ttttcctcgc
    28801 cctgagactt gtaggactgg taaagagagt aggctagatt ctgaccggcc aaggaagcac
    28861 ctgtttcaat agctgactta gctgtctggt aatcgcgaat tttagcctct gtttgactga
    28921 tgaggttgcc gatttcggat tgggtttggc tagctgctgc attctgggac gcgatggtct
    28981 cattttgttg cgatgtacta gccctaagac tgcctgcttg actgatgtag tcgcgaaagg
    29041 tggcttggta gccaaactta tcctcctctg gaaagtggtt ctccccttct tgcaggctct
    29101 tttgcagata ctccaattgc tttttttgat cctttagcat gtccaactga ctggcatagg
    29161 actccgcttg gacaccctct gccccttctt ggtattgaac caaaagatcc cccttcttaa
    29221 ccagcttatt ttcttccaaa tgattgacaa gaatacgatt gttgctagtt gactggatat
    29281 ttgcaaggat acgactgggt tcgacagtag ctctagtgga caaactcatc tccttctctg
    29341 caacagttgc aaagccaagt aaaaacacga gcagaagggc catgggtaca atcacactac
    29401 tggaaaaatt atggtaacga cgattataaa actccgcact ttctaaaaat tctggtttca
    29461 tcctctcctc tttctagcta ttgaccaaat gggcgtaaaa gccaccctgt gcaagcaaat
    29521 cagcatgctt tccttcttcg acaatcttgc cctgatccaa gacaactacc ttctctgtcc
    29581 gctcagcaat agtcaagcgg tgagcaatga aaatcaaggt cttgtccaaa gctatgagat
    29641 tatcgacaat ccgcttctct gtcaaaatat ccaaactgct agtcgcctca tccaaaatca
    29701 agaccggcgc atctgtcaag agagcacgcg ccaaagcgat tctctgacgt tgaccacctg
    29761 aaatccctgc cccatccgaa gtcaattctg tctgataatt cagtggcatg cgctcgatat
    29821 cctctcgaat ctctgccaat tcgaccgccc gtaagatatc ttcctgtgtc gtcccctcct
    29881 tggctcccaa aagaagattc tccaaaatcg ttccgttaaa gacatagggc tgttgaggca
    29941 gatagttgat gtactggcgc agggcttttt tatcaatctg attgagattg acactaccca
    30001 gactaatctc cccttgactt gggtcgtaaa aattaaccat catcttggcc aaagtcgtct
    30061 tacctgaccc tgaaatcccc acaaaagcca ccttagaccc ttggggaacg gttaaattga
    30121 tatccgacaa gacgtctcga ccatagccat acttgtaatg aacctgcttg aaggtcatat
    30181 ctcccttcat caagctcaaa tcctcaactg ttttcttctc ctcaaactca gaagctacta
    30241 gatacacttc atttagacgg ttattggcaa cctgcgctgt ctgaagcttg gtttgcagat
    30301 tgatgatatt ttccaaagga ttggtaaagt aaaccagcaa ggtattatag gtaatcaact
    30361 gccccaaact catcttgcca tccatgacca gaacagcccc catccagaga atgccgacat
    30421 taagcaagag atgggcaacc tttttcagag ccttttgctg actctctgct cgactatagg
    30481 taaaggattt cttcagataa tccacaaatt ccttgtcaat tttttggtaa cgctgacttt
    30541 cactggtcaa ggacttgata gtctcaatac cgttgatgtc ctcaatgata gaagaaaaca
    30601 gaaccgcatt ggcttccatg gtatcccgat tcatcttttc aaacggcttc ataaaggcaa
    30661 agataatcac tgtgtagata ggaagcgcca ataaagtcat gaaaaagaga ttggtatttt
    30721 gtgaaaatag aacaagggaa ataatgacaa ccgttgacac atctaggaaa atcgaaagaa
    30781 tggtcgaagc cagcgcatcg atgatactgt tagcatctgt aaaacgagac acgatctccc
    30841 ctgtcctgcg tgtcgcaaag aaggacatag ggaggtgaaa aacatgcttg atataggaca
    30901 aaatcacgtc aatcgacaag cgttgcccca aaacaagcaa gagatactcc tgagcgtaag
    30961 acaagatttg ctggaggatg tagacgatga ctagcccaat agaaataatc cctagtgtcg
    31021 aacgcatctg atctggcaca taggtatcaa tgatagactg cagataataa gaacccacaa
    31081 tgttaatccc ggttaccaag agtgttgcca aaacgatatt ggcaatcaag ccacgctgct
    31141 tcactaatat agggataaaa gagagcagac catttttttg ttccttataa ggcttatagt
    31201 ctggactagg tgccataaaa agagtcactc ctgtccattc ttcctcaaaa cgctcacgtg
    31261 gcagtttagt caacttcacc ccgggatctg gatcggcaat atgaatgcta tccttatcct
    31321 gcccagtcac cacatagtag tggagcaatt tcccttcctt aagcacatgg gcaacaaaag
    31381 gaaaagtcaa atccggcaag tcaaaaagcg tcatatccgc cttaatggct cgcgtctcaa
    31441 aaccaatctc ctctgccacc ttgaccaagc ccaaagccgt cgtcccatcc atggtcgtct
    31501 tagccaattc tcgcaagtga gccaaaaaat aataactacc atagtagcca aaaaccatgg
    31561 ctaatgaagc tacaccgcag tccatctgat ccacttgcgg acgatagtga cgtttcccaa
    31621 atttcatatt catctccttt tccctaatac tcaatgaaaa tcaaagagca aactaggaaa
    31681 ctagccgcag gctgctcaaa acactgtttt gaggttgtag ataggactga cgaagtcagt
    31741 cacatatata cggcaaggcg acgttgacgt ggtttgaatt tgattttcga agagtataaa
    31801 ctcatctgat aacaactatc ttaccccaat cactaaacaa aaactggact tccttcccaa
    31861 atgagcctat ctccctccca actgcacttt ttggataaaa aaataggcag aacaaacgtt
    31921 ctacctagaa aatataagaa ttacaagtta acaaaaccga aatgatttca tatcattatt
    31981 aagtaaagaa aaaaatttta gtatttctaa aaactattta taatagacat tatagcatta
    32041 aataaaaatg gtacagaaaa cactactgtc aatcttaaat ttttaaatct cgcatagttt
    32101 gttatcccaa ttagtaatac tgtcaatacg ctgaaatagg caaactttat atccgatgga
    32161 ttaaataaat aacaaagtaa aatgctaaaa cttaaggtta tatttttaga taaaagaata
    32221 tctccaaagt tcctcttatt cttatcaaaa aataatgtaa tcagaaagag agaaaatcca
    32281 tattcaataa gagttgctat aaatgtgaaa acaacagaaa tcactgtcaa tattgtttct
    32341 attttaattg taaaaagatt agatagttca gataatttat caatttgttc atctaaaatt
    32401 cccgacttca tcagtaaatc aataaacaaa tataaaagaa aaagataaat aatcagattc
    32461 attaatttgt ataaactatt atttgtttga aatttcataa acccgtcctt cctctattaa
    32521 aatcctttga gatttgctaa tcaattcttg attcaataaa ttatgagata catatataat
    32581 agtagagctt tctttcatgg aaattaagcg tttagcaatc atatcaatac ttcttgcatc
    32641 cactgttgat aaagtctcat caataaaaat ataatcccaa tttttagcaa aaattaagga
    32701 taagcctaat ttgaattttg ttccagtaga tgctgtcata tagttatctc cgattttatt
    32761 atcaaaaaaa gtattaattt gttctttatc ctcaaatgat agatggattt gaaaagaatc
    32821 acacaacaac tgcaaatttt cttctatagt aaatggaaca accccaagct gattggtatc
    32881 aaggtatagt acatctttgg agacacaatt ctttaaacca ctatcaaaag tctctagccc
    32941 agctaaaagt tgtagaaggg tgctctttcc tgaaccattc tctccttcaa ctctgtaaat
    33001 tcccttatca atctctagtg atatattttt caatatacat ttatcataac ttttagattc
    33061 attttcaatt ttcataattt aattccctct atcaacgctg ctaaaattaa taaaagataa
    33121 gaaataatat accattttaa attacttttt atataaataa gtatattttt aattccccta
    33181 tccttcaata atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt
    33241 atttcaataa gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga
    33301 ccagatatac ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa
    33361 atcggaaaac agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat
    33421 gtaaattgta attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag
    33481 cttaaaagta aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa
    33541 ccactttttc tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata
    33601 aaaccagaaa actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct
    33661 tataatagac ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac
    33721 tttttatatc attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta
    33781 agaaagagat taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt
    33841 tagaatgatt aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat
    33901 gattccctat tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg
    33961 gtatttttgt gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa
    34021 gaatactaat caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca
    34081 atataaatag actgctacga aatctttttt gactcattcg actgctttta aaatagaaat
    34141 tactcgcatg attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat
    34201 aaataacaac ttgtccttgt tctatagaca atagtcctat agataaaaat aagaacaatt
    34261 tacttataat tgaaaacaaa ctaggtagaa ttaaagaaat aatttgaata gctatcaaac
    34321 aaagagtaat ggataaataa aaatatccaa taatatctag aaaatacaaa ataaataaat
    34381 aaataaatga atgattgtaa aatttggaaa gaataatatt tcttgacaat ggcaagaaga
    34441 tagagaaaaa tatagttttt ccttatatag aaagtattta tttttttact ttggataggc
    34501 agtttcatat tataacgatt caaagtagcg taatctacta ccaaaaaaag taaaaataat
    34561 ttcccttgaa aaggaagata gcttttaaaa tagattgaca aacttatgat aacaaaaaac
    34621 aaaagggtta tcccaataaa attaagataa cctaaaatac tttcacattc ttttttagaa
    34681 agtattttca tctagttcta ccatagagct gctttagcag cacctttctt tttcaatata
    34741 taaagaactg ttgctgcaat acccgaacca atagaaccta ctcctgtgat tgcacctaca
    34801 attgaaatta ctgctgtaac tgtactataa gcactaatca aattgactac agtagcagca
    34861 gcttttgtcg aaattcctaa tgtcccagcc aacataggaa aagaaacaac acctaagctt
    34921 aaccaactaa tgactgctaa cattgctgaa acaataagaa atttattatg aaattccatt
    34981 cttttagatt tcattttagt gtactccttt tgtatattat gtatgtttta ttgagagtta
    35041 attcgcacat gttgtattcc taactctctt caaatgttcg tctatatttt atactacttt
    35101 tattaacata tctataataa ataaattact actacatttt cctagattat caaattactt
    35161 ttatatcact aagactcaat aaaagataat gtctatttaa cttttatacg attactacct
    35221 cctttttagt ttacacttcc tacatcataa ataaacatac tcaaccctca caatctccaa
    35281 ataactcttc tatatcattg aaaattgagt ttcatcctct atactaatgt aggaaaccta
    35341 ttaaaacatt cctttaatcc aatataggaa taccttatgc cattaatctc tacctgatat
    35401 tatagataga accagactcc tatacttaaa aggacaaaca acgttccaac cataataaac
    35461 ttcctttctt tttggaatcg ttttctttat gagtttagta taacaaaaac atgaaaaaaa
    35521 caacatgact tagaagtcag gttgttggga aatctatttg tttttctgct aaaattttct
    35581 gaactaatac ctgatcatct agcaattctg ctagagaaat cgccttttca tagaaacttt
    35641 ctgcctctgc cacattctta tctacaaata aagcatattt cgcctttaac aaaaatagat
    35701 gaggtcggta aaaaacatgt cttgttttag caataatttt ctcaaatgtt tgaatatata
    35761 tcagactatc ttctgtctga atttggataa ataggctcag aagaactttt tccatctgaa
    35821 ctaggctatc cttatcttca tattctgaac atagcaatac tttttgagct aactcctcaa
    35881 aatgttcttt atcttctaat cccatagcac aacaaaagaa atacaattca ataatcaaca
    35941 aatcatttac agaaaaatat ttctttttta ataactgctg gaaatattct tccactaacc
    36001 ctaaaccgta ggtcacatct gaactaccat aaatatcaaa acgagcttgt gtcacatcca
    36061 caattaactg ctcttcctca ggcaaattct cataatagtt ttcatatatt tcctcaagta
    36121 tagcttcttt tcgttcgatt cttcccttat cagcgtaggt ttgagaatga atcagctcat
    36181 ctttgagttt taggaatcct tttggaatct ctataacctt aacatccaca atattctgta
    36241 atgatactcc aagtttatcc gcaatcaata ataatttagg aagtgttgct aaagcttgcc
    36301 cattttcaat acgtgctagc tgacgaatcg tcaactctga ttcatcacca caaatatcta
    36361 tctgagtttt tccacaagat cgcctaatag ttttgatttt ataaccaatt tcacgtttca
    36421 actcatccat agtaatactc cttaagttga ttacaaagat ttctttttct tcctaattct
    36481 tttgtcaatc atatataaaa cgataagcga aaacagcggt agaacaatat aactcttttc
    36541 actcattatc agctgaaatc ccagggttgc tagtatctta aagatgaaaa tattcatcaa
    36601 aaatagaaaa acaaatacta aaaaatattt taaaaccttc ttcatttctt ttcttcaact
    36661 ttcctaattt ctacacctat tttatcgaaa atatatataa aactccaaat aaacacttca
    36721 actgcacttt ttttggcaaa aaatagacag aacaaacatc ctacctacta aaaatatgat
    36781 atgaaaggaa aatgattttt tactgacacc ctaggcaagc ttgggacaaa taaatcattg
    36841 atagcaacat ttacgacatc ctatttaaag ttccttcaat ttctaatgtc cccgctattt
    36901 ctaagctacc tctggtatga tctattccta gtcagaatag ataacaccgt tctaaattac
    36961 gattcatagt tactcctttt ttgactcgtt actataagac tcctctttac atgcgcaaaa
    37021 taattttgat tcagattcat catttatagt tttgattatt ttttaacaga tttttctgtt
    37081 ttcttctccg aagactttaa aaattttttt ctaattaaat catccatata aggaccaaat
    37141 ataccaacta ctaaaccaat aataaaactt ttaaaatcca taattaccac caacatgtcg
    37201 ctgcataggc cacacctcca agtatagctc ctcccgcagc accagttgct gcaccttgcc
    37261 atgttcttgt tttaattcct agctgaagac ctcgtgctgc tcctcctcca acacctgctt
    37321 tggcaaaatc tccccaattg catccgccac cttcaacgca agcaagcatc tcagtatcca
    37381 taatttcaaa ttgtgacatc ttttttgtat tcataacgaa tacctctttt ttatttttaa
    37441 tatttgtctt gttacaaact tgacaagttt agtataacag tatctattaa tttttttcat
    37501 ccaaatcttg aattggcatc gaaacgtctt gaattagctt ttttgtttca aaatcatctc
    37561 tatttttaaa aaagatgttt tctaatcact tttttactat tagacttcct gcaaaactag
    37621 aatcctagtt catgattgat aataccagca atcaaattca ttcgtaatcc gaagcgttta
    37681 cgatgatttc gataggttgt tgaaaacatt ttaaacgttt ttactttggc aaagatgttc
    37741 tcaaccttgc ttctctcctt agatagcgca tggttacagg ctttatcttc aactgttagc
    37801 ggcttgagtt tgctggattt acgtggagtt tgtgcttgag gatatatctt catgagccct
    37861 tgataaccac tgtcagccaa gattttacca gcttgtccga tatttctcat ttctaaaaac
    37921 catctacttc cgttgacttg gaactccgat tgctattttc cttgaatgat tttaaccaca
    37981 tctcctacac tttggagttg gtcaatttcc tcatcgctga tttcgatact aaattcatct
    38041 tccagagtca agataaactc catcaagtca acagaatccg catccaaatc gtctttcaga
    38101 ctcaaggatt ctgtcacgac aaagtcctct ccctgtcgct cttggataat ggtcacaata
    38161 cggtcaaaaa tttctttttc tgtcatctct tttattctcc tgaaaattca cgcgcagtct
    38221 gggcaaccac gtctgtttct agcatggtac gaatctgacg aatcgtacta taaacagcct
    38281 tggcatcgct tgagccatga gtcttgacaa caggtgcctt aacaccaaac aataccgctc
    38341 caccaacatc tgaataattg agctgttttt tcaaaccact gaggctgtcc ttgagaagga
    38401 gggcacctag tttcgctcga agaccaccac ctgtaatagc tgtcttgagc aagcccacga
    38461 ttcccatagc tgtcccttcg atggatttga gcacagcgtt tcccgtgaaa ccatctgcca
    38521 caacaacatc tgcaacgcca ttcatcaaat cacgcgcttc cacgtttccg ataaagttca
    38581 aactttcatc agccgccagt aattcataag tttccttacg aagcgggtcg cccttgctac
    38641 tctctgttcc gttgttgagc aaaccaacgc gtggttgcgc aatgccacgg acatttttag
    38701 catagaagga acctagaacc gcatattgat ggaggtgctg ggctgtattt tctgcattgg
    38761 caccaaggtc tagcatgtca aaaccttttc catcaacggt aggcaaggta gacatgagtc
    38821 caggacggtc gatattcttg atacgaccca cgatgaagaa tcctgctgcc aacaaggcac
    38881 ctgtattccc agccgaaagg acagcgtctg cttcaccatc tttgacagcc ttggctgcca
    38941 ataccatact ggcatttttc ttattcctaa tagctctcgt aggttcatca tccgaatcaa
    39001 tcttctcatc cgtatggata atgctgacgc gctctgtcgc tgtcagatat tgcttgattt
    39061 tagcttcatc tccgtaaagt tgaacctcga tatctgaaaa gtcagatagg gcttgattga
    39121 caccctcaac aatggcctga ggtgcgtaat cgccccccat ggcatctact gcgatttttt
    39181 tcatttcttt tcctctttta gtaattgtcc ccagtctgct agggaatcaa taaatttctt
    39241 tgattttagg tgaatcccaa cgtactcttc atataattga tccataaatt ggcgtagctc
    39301 ttgcttgatt ccaggcttga gcgaaatggt ctccaaagtc tcaaaatcaa tagcttgaaa
    39361 ttgattgagc agatagggga tattgggatt gagatgacaa cgtctcttat cctcatgata
    39421 atgctctgga cagaggcagg ctccatattt gaaagaaaag tcaaaagcct gaccaacccg
    39481 atggcagaag acacactcat taaaattgag gctgattcca aatcgagtca aaatttgaat
    39541 ttcaaaaata ttggtcaaaa cctgataatc caagcctgct tccatcaact ccaaagtctt
    39601 ttgcaaaaaa gcaaacaagg gagcatcctg ctgattgtcc tgcaaactag catctgcaag
    39661 agctgccaca taggtcgcat aggccatgac aaagaggtca ctattaatct tgggaaaagt
    39721 catgacctca tgatagtctt cgatgtaact gagtccgtca tcattgattc gcaagagaaa
    39781 tcgtgccagc accaagggct gaataacagg cgccagctta gactgaccag cgtgtttgac
    39841 aaaaaacatg cgtttgccaa cctgctctgt aaaaattttg acgagcttgt catcctcacg
    39901 aaaattgcga ttgtaaagca ccaagccttg actcgtgata gactgaatca tgcttctctc
    39961 atgtactcct caagtcgttt catggcttct ttgatagtct ccatgctggc tgcataagat
    40021 aggcggacgt agccttcccc gtaacgtcca aaggctgcac cagggataaa ggcaacggcc
    40081 ttcttctgag caaaatcctt cagaaaagca aaggagtctt gattgtagcc cgctggaatt
    40141 ttagcaaaaa tatagaaggc accgtctggt ttgataatct caaaaccaag agcagtcatt
    40201 ttttcgatga tatagtcccg acgctggata tattccttct tcatgggctc cgcatcattt
    40261 ttaccagccg tcaaggcttc taccgcagca tgttgcgcca tggtatttgc ggcagtgacc
    40321 aagtattggt gactcttgat taactgggct gtgaaggccg caggagcgaa aatcagcccc
    40381 aaacgccaac ctgtcatggc atgcgattta gacaaaccat tgataataat agcctggtct
    40441 ctcaacatcg ttcctagaga cacatgggct tcgcctgtgt aggtcaattc tgagtaaacc
    40501 tcatcacaga caacaaaaat ttcgtacttg cgtaaaacag ctgccaaggc ctctaactgc
    40561 tctcgactgt aggtaattcc tgtcggattg gctggatagt tgagaataac cgccttgagc
    40621 ttatcaccct gctccaaaat ggccttctcc aacatctcag gagtcaagac aaaaccattt
    40681 tcagtcgtat caatctcaac aatttctgcc ccaactaagt taacaatcgg ttcatagcct
    40741 ggataagcag gagctggcaa aagtaccttg tctccctctt ccaaaatagc cgtcaaagtc
    40801 gcagataaag cctctgtcgc cccaattgta accaagattt cattttcagg agcatagtcc
    40861 agttggtact tttccttaac aaagtcactg gctgcctgac gtagagtcag cagaccactc
    40921 atccctgtat agtaggattg gttctgatca atcgctcgct tggccgcctc cttgacatgg
    40981 tctggcgttg taaaatcagg ttcccccaag gtcaaacgca agaccccagg aatctccgaa
    41041 ataacctggt caaactgacg aatcaacgaa acttgaattt tatctaactg tttattaaag
    41101 cgcttagtta agtccataga tacctcctac tttcaaaacg tatctctatt atactacaaa
    41161 agccccccga ccgcaaaaat acattagaga atagctttcc actttctatt ttacttttcc
    41221 tgtttacagg tctataatgg taacagattc tatttggagg tttttatgtc atttctatca
    41281 aaaaatggag caggcatctt tgtctgcctt ctcatttcta tcgtatcttg gtacttagga
    41341 ggattcttcc ctgttattgg cgcacccgtt tttgcgattt ttatgggcat gctcctacat
    41401 ccctttctct cgtcttataa acaactggat gttggattga cctttagttc caagaaattg
    41461 ctccagtatg ccgttatctt acttggtttt ggtctcaata tctctcaagt cttcgcagtt
    41521 gggcaatctt cactccctgt catcctttcc accatttcaa tagccttgat tgttgcctac
    41581 ctcttccagc gcttctttgc cctggataca aaactggcta ccttgattgg agtaggttct
    41641 tctatctgtg ggggttctgc cattgcagcg acagcgcctg ttatccatgc taaggaaaag
    41701 gaagtagccc aagccatctc cgttatcttt ttcttcaatg tcttggctgc gctcatcttt
    41761 ccaaccctcg gcacctggct tcatctatcc aatgacggct tcgccctctt tgcaggaact
    41821 gcggtcaatg atacttcctc tgtaaccgcc acagctagcg cttgggacag tctctaccag
    41881 accaataccc tcgaatccgc aaccattgtc aaactcacgc gcaccctagc tatcatcccc
    41941 atcactctct ttctctccta ctggcaaagt cgcgagcaaa aaaataagca aggcttacaa
    42001 ctgaaaaaag tcttcccact ttttatcctt tacttcatcc ttgcatcgct cctaaccacc
    42061 cttctgacct ctctcggtgt gtctagtagt ttctttaccc ctctcaaaca actctctaaa
    42121 ttcctcatta tcatggccat gagtgccatc ggtctcaaaa ctaatctggt cgctatggtc
    42181 aaatccagtg gaaaatccat tgttctcgga gccgtctgct ggattgccat catcctcacc
    42241 agccttggta tgcagaccct tatcggcatt ttctaatact cttcgaaaat ctcttcaaac
    42301 cacgtcaacg tcgccttgcc gtatatatgt tactgacttc gtcagttcta tctgcaacct
    42361 caaaacggtg ttttgagctg acttcgtcag tcgtatctac aacctcaaaa cagtgttttg
    42421 agcagcccgc ggctagtttc ctagtttgct ctttgatttt cattgagtat aacacaaaag
    42481 gtagcccatc agctaccttt ttcttatgct tcctcaatca agcgagtatg ttctctcttg
    42541 atacagcgat tcatcacgat atcatcacat ccaccatcac gcaaaatctc tttcgcttct
    42601 aaactttcaa gtcctagctg tgcccaaaaa atcttggcat cagctttgag aaaatcacgc
    42661 gccacatcgg gcagaaattc actgcgacga taaacattga caatatctac aggaaaagga
    42721 atttcagcga ggctagcata agccttttca cccaagattt cgccacctgc cgccttggga
    42781 ttgactggga tgattttata gccccgagcc tgcatttcct ttgtcactcg attgctggtt
    42841 gtttcttcac ggtcagacaa acccaccaca gcaagggttt tactcgttgc gagatactga
    42901 cgtatcacgc catcacttgg attgataaat tcttgactca tagaaatcct cctttttcat
    42961 cagtatagca cattttgaaa aggtttgcag aattctacta caaaaaagga ggactagccc
    43021 cctttttatt tagcctcgta ccaggttgct ccttcattct catctgcgat aagaggaaca
    43081 ctgagttgaa tggcttcttc catggtttgt ttcaccaatt ttttcatctc taccaattca
    43141 gatttaggca cttcaaggac gatttcatcg tgcacttgta acagcatctt agtctgataa
    43201 ccacctgcaa ccaaggcttt atccagctga atcatggcaa tcttgagaat atctgctgcc
    43261 gaaccctgga taggtgagtt gatagcagtt cgctccgcaa aaccacgaat attgaagttg
    43321 cgcgaattga tatctggcaa ctcacggcga cgcttaaaga gggtctctac atagccctta
    43381 tcacgcgcct cccgcaccac ttcatccatg tagtttttaa tacctggaaa acgttcaaag
    43441 taggtatcaa tgtaggcttt ggcttcctta cgactaattc ccaaattatt agacaagcca
    43501 aagtctgaaa tcccataaac cactccaaag ttaactgcct tggcattgcg acggtcattt
    43561 gcagtcacat tatcaggacg ctcaatgcca aagacccgca tggctgtcga agtatggata
    43621 tctgccccct cttggaaggc cttaatcaag tgctcatcct tagaaatatg cgccaaaacg
    43681 cgcaattcaa tctgtgaata gtcagagctg agtagcacac tatcctccca ctctggcaca
    43741 aaagccttcc gaatcaagcg cccttgttcc aatcgggcag gaatattttg caagtttgga
    43801 tccacactag acaaacgccc ggtctgggtc aaatcctgca tatagcgagt atgaatcttt
    43861 ccatcagcca aaatccagtc ctgcaagcca attacataag tagattgaat cttagcaatt
    43921 tgacggtaat ccaggatttt cttaacaatc ggagcaatag gagcgagacg ctccaacaca
    43981 tccactgctg tcgaataacc tgtcttggtt ttcttagtgt attctagagg aagtcccaat
    44041 ttctcaaaga gaagcacgcc caactgctta ggcgagttga cattaaactc ctcaccagcc
    44101 agctcgtaaa tctcttgagt cagtttttca atgacaagct cattttcagc ctgcatctca
    44161 agcaaggtct ctttcttgac cacaatccca gcaatttcca tcttggcaag aacaaaagcc
    44221 agaggttgct ccatatcata aagaagctct aattgcccat tttcgctgag tttttcaagt
    44281 aaaataggct ctgtttctac caaaacagca agtttacaag ctaagtgttc caaaaatttc
    44341 tcacgttcag gaatggcctt tttaacaccc ttaccgtaga aagtttcatc atcaaccaag
    44401 taagtctgac cataaagact agcgatggtc gcaatttcat tgtcctccac agtcgaaagg
    44461 aggtatttag ccaaacggat gtcaaaagca ggcgcctgca aatccacacc aaaacgttgc
    44521 aaaagaactt taaccttctt aaagtcataa actctcagag atgttttttc taagaaatcc
    44581 ttgaaaatcg ggtcttgcaa cagctcaagc ttgtctgtgg catagagctt atccccacaa
    44641 gaccaggcaa atccaaccaa attatccgta tggtaattct caccaaaaag ctcaaagtgg
    44701 aagatagact cttcactcag catatcttga ctgatttggt caacaatagt aaaatccaaa
    44761 ccctcagcca catcagctga cgacacattt aaagcctgct tgagctgttt gaatcccatc
    44821 tcatcgtaaa atttcccaag attttcaaca tctggaccac catagaccaa gtcctctaaa
    44881 ccaatcgcaa tcggtgcctt ggtatcaatg gtcgctagtg ttttagacaa aaaggcctgt
    44941 tccttgtcat tgatgagatt ttccttcatc ttagaagtct tcattccatc aatattttca
    45001 taaatcccct caagcgaacc atgctccagc aagagcttaa tacccgtctt ttcaccgact
    45061 ttggtcaccc cagggatatt atccgactta tcacccatga gcgccttgag atcgataaac
    45121 tgagctggtg tgaggcccat ttcttccatg aggtaatctg gcgtaaaggc ctcaaactca
    45181 gccacacctt tcttggaaat ttcaaccacc gtatgctcat ccgtcagctg aatcaaatcc
    45241 ttgtccccac tgacaatggt aatatcaaaa ccatcctgct ctgctagctt atccagcgtc
    45301 ccaatgatgt catccgcctc atactgagcc agctcatagt gacgaatccc catataatcc
    45361 agcaactcac gaatgaaagg aaattgctca cgaaactcat caggagtctt ggcccgacca
    45421 cccttatagt ccgcatacat ctctgtccgg aaggtcgtct ttcccgcatc aaaagccacc
    45481 aaaatatgac tcggctcaac ccgctccaac aaatgactca acatcaactg aaaaccataa
    45541 atcgcattgg tatgcaaacc agccgcattc ttaaaacggt ccaactgctg atacagcgca
    45601 aaaaacgccc gaaaagctac agaagaccca tcaatcaata ataatttttt cttatccata
    45661 cacccattat aaaggaaaga atcaaaaaat accattggga agagctagag caagtatttt
    45721 tcaaactttt tccgaataaa tagatagagc cagagaattt agtaaaccta gatttaaaaa
    45781 tgtgctataa tatagtatat tgaatctata atagtacacc ttgactgcta aaatatttct
    45841 ataaattaat ttgactttcc tgatagagtt attcacatct tatttcaact cactatagaa
    45901 ggaggaaaag gagggctggg tggctaactt cattatagaa ctttcaaaaa gatgaaaaaa
    45961 tagcgtcaaa gaggcttttt tctctttaaa acaggaaatc tcaaagacaa tcttgcgact
    46021 atccaaactg tacgaataac gagacataac ttacttcgct aatactatct tataaaaaga
    46081 tagaaatgtc aagcaaaaat gacaagtatt ttgataatag acttgccatc ccatcaactt
    46141 tctactatat aaagtatgaa ctcatagcaa ggactcaaac tcagccacgg tcatgcctaa
    46201 ttgctcactc gcaacctcag gtgttagaag accttgacgt actagattta ctaaacctac
    46261 ttttaatccc tcttcaaggc cttcttctcg tccttgttca ataccttcag ccctagcggt
    46321 ttccaaggca tagtcctgtg ctaacaagac ttgttcttct cgcatatgta gttgactaaa
    46381 cattttcctg tcctcctcgg accagctctt gtagtccagc agttgatttg cttgggtaat
    46441 ggctcgttgc ggttgctggg taaagggctt gttgccgaaa aactccaacc atggcttgcg
    46501 aaccttgtct ttgctggttt ctctgtattt tttaattcca agaatgccat cttaaccaga
    46561 tggttttcct gtccattgtt ggtaatcgcc aatacctcac ctgttgtgtc ttcgcgcata
    46621 ctaaagctat gaaaagccag gtcatctgag aaataattac tatccacgat agcaatggcg
    46681 taaacaggag cgatgtgttt gtagctctag tgagtatcac cttctcgctg acgaattttt
    46741 tcaagatttt gattaacctg actgcacagg taagcccaca agcgattgat gaaaaaattc
    46801 tgatgatgga cttgaatctc aataattact tgagtaccgt tatccaactc cgccaagacg
    46861 tctatactgg tataaaaatc ctgcaccgag taaggcatgg agagtaatac gtgaatattg
    46921 ctaccctcca aaatggtcac atttttggct ggcaaatcca gcatatcgcg aataaattga
    46981 caagtgattt ctggattgct aaagattttc ttagctacca agtcattggt tgggctaatg
    47041 cccggatgac gtacagtcat atttcttctc tttttattat atcacagttt taaatctagc
    47101 tttactagat tcaccgctac tatctattta ttcggaaaaa agacgaaaaa acctgagaat
    47161 catctcaggc ttggtcatta aatttttttc tcaatatcga aaagtggaga aagtggtcgt
    47221 ttttcatgaa tacgtacgat agcatcccct aggagatgag cgattgaaat ctgctcaatc
    47281 ttatcaatca aacgctcttc tggcagatag atggtatcca aaacaaccaa tttcttaata
    47341 gctgattttt ggatattgtc cgtagcagga ccagaaagaa ctgggtgcgt acagcttgca
    47401 tagacttcaa cagcaccagc ttccgcaaga gcatctgccg catgacaaat cgttccagcg
    47461 gtatcaatca tatcatcaat caagatacaa gtcttgcctt caaccttacc gatgatgttc
    47521 ataacttcac tagtattcat cttatcaacg ctacgacgtt tatcaataat agcgatagat
    47581 gttttcaaaa attctgccaa cttacgagca cgagtcaccc ctccatggtc cgggctgaca
    47641 accacatagt cagaaccaac cataccacga cgctcaaaat aatctgcaat cagaggagca
    47701 cccatcaaat gatccacagg aatatcaaag aatccttgaa tttgcgcagc atgcaagtcg
    47761 atggtcaata aacgatccac tccagctact tcaagcatat ttgcgacaag ttttgaagtg
    47821 attggctcac gcgctctcgc ctttctatcc tgacgtgcat acccatagta aggcatgaca
    47881 acattgacag attctgcact cgcacgcttc aaagcatcta ccataatcaa aatttcaagc
    47941 agattgtcat ttacaggcga actagttgat tgtaagataa agacgtgttt cccacggatt
    48001 gattcttcaa tgttgacctg aatctctcca tctgaaaatt ggcgaacact tgatttcccc
    48061 aactctatcc caatctcctg cgccacacgt tctgccaatt ctttattaga agaaagggca
    48121 aacagcttta aatcagaaaa agacatgatt tcctccggta tatatgtata acttgtgctt
    48181 ttcacaagat tttccatcta ccattgtagc gctttttgca ctatttttca atcaaaaata
    48241 aaagaagggc accatatttg tacccttgca tcattctttt gaaaaatatt ctaggtcatc
    48301 aactcattat gtttctcaac aaagcaataa gcatgataaa aaccatagag agcaatagcc
    48361 gtaaccactg gaatcgctaa aggcaactct gtttccaact ccacaaaagg agagttaaac
    48421 aagaagtgag ttcccaaggc tagacctagg aaaataagtc cctgtttctt gccaatcttc
    48481 tgtcctttat aggctctgta aagcaagtaa acccccacca cagccagacc tgaaaaagtc
    48541 cagtgagagg caattcctga gatgatacgc tctaaaatcc tcgaaatagt aaagtcaaat
    48601 ccctccggta aatccgtacg aatatagcca atatcctcaa tcatttggaa tcccaaacca
    48661 gaagcagtcc ctagtaaaaa caaagatttt aattttcgca caggaatcaa agctaaaaca
    48721 aaaacaagtg gcaacaattt caagggctct tctaccaaag gagccacaat cgcactttca
    48781 aaggcattta aaaaagcact atctgggaaa agaccaccca gtaaatcatg gatataggta
    48841 ttcgcaaagc tagacaacca gcctgaaagg aacatcccac ccaataaaga caagatcaag
    48901 gcgttctttg gcaattccca ttttttccca atacggaaaa ggaaataaag agccggaatc
    48961 atgtaaaaga gagctagaaa gatagaaact cccattagtc catattccgc gcctgatatc
    49021 gaaccatccg tatagtagat ggtttcatac tgtaaaccaa tacatagcaa taaaataaaa
    49081 ataaataaaa tactgttttt cttcatacac tttctttcta aatgaatttt ttacaattct
    49141 acaactgtca tacttcctgt atccacatcg taaatggcac cagagataat gacatcgtct
    49201 ggtattaggg aagattcgat aagcagtttc atatcctctc gcacactctc ctctatatct
    49261 tggaagggca agaagtcctg gtctgacata tcgacaccta gttcctcttt cagatactcc
    49321 tgaaaaggac cattttcaaa ggtctgagca ccacagtctg tatggtgcag caccacaatc
    49381 tctcttgtcc ccatttgttg ttgggaaata actagcgaac gaatcatgtc ctcagtcact
    49441 cgaccacctg cattccgcaa gatatgagca tccccaagtg ccaagcctag agcttgtgca
    49501 acgtgcagac gtgagtccat acaggtcaca atggctactc ttgttttggg tttaagtggc
    49561 agatttaact gcccatgtag ggcaacataa gcctgattgg cttgcataaa ctgttcaaaa
    49621 tacgacacga ttccctcctt gaaaatttga tagtcaaata tttctcctat cttatcattt
    49681 ttaagaggat ttgtcacgga ttatgcaaaa acctttttca aaacttcctg aatggtagtc
    49741 acaccaatca cctgaatttc cttgggcgga gtgatccctg tcaaagaatt tttgggtaca
    49801 taaatcttag taaagcccag tttagcagct tcgttgatgc gttgctcgat acgattcacg
    49861 cgccgaatct ctcccgtcaa gcccagttcg cctacaaaac attcctgagg attggtaggc
    49921 ttgtctttat agctcgaagc aatagcaacc gcaacggcca agtctatcgc aggttcatcc
    49981 aatttgacac cgccagcaga tttgagatag gcatcctgat tttgcaagag aagacctgcc
    50041 cgcttttcca aaacagccat aatcagacta gcacgattaa aatcaagtcc tgtcgtcgta
    50101 cgcttagcat ttccaaacat ggtcggtgtc accaaagcct gaacttccgc caaaatcgaa
    50161 cgcatccctt ccatggtcac aacgattgat gaaccagtcg ctccatccaa acgctcttct
    50221 aggaaaactt gactcggatt gagtacctca accaaaccgc ccgactgcat ctcaaaaatc
    50281 ccaatttcat tggtagaacc aaaacggttt ttgaccgctc tcaagatacg aaaggtatgg
    50341 tggcgctccc cttcaaagta aagcaccgta tccaccatat gctccaacat acgaggtcca
    50401 gccaaggtac cctccttggt cacatgacct acgataaaga tggcgatatt atttgtctta
    50461 gccaactgca tgagctcagc cgtcacctca cgcacctgag aaacagaccc ctgcacccct
    50521 gaaatctcag gagacataat ggtctgaatg gagtcaataa taaggaaatc tggttggatg
    50581 cgctctactt ctgcacgaac actctgcata ttggtctctg catagaggta aaactcgcta
    50641 tcaatatcac ccaagcgctc tgcacggagt ttaatctgct gggcagactc ttcaccactg
    50701 acataaagaa ccgttccaac ttgagacagc tgggtagaga cttgtaggag aagggttgat
    50761 tttccaatcc caggatcccc accgatgagg acgagacttc ctggtaccac tccgcctcca
    50821 agtacacggt tgaattcctc catctccgtc ttggttcgat tgacattgat tgaagtcacc
    50881 tcagccagtt tcatgggctt ggttttctca cctgtcaagg acacacgcgc attcttgacc
    50941 tcggcaacct caatctcttc tacaaaagaa gaccaagacc cacagttggg gcatcgtccc
    51001 agatatttag gggaattata cccacaattt tgacatacaa atgtcgcttt tttctttgcg
    51061 atgataaacc tctttctata tctctaactc acactcaatc acttggcaaa aatcaatctt
    51121 ctcatttggc acaaactggc gcatgagcat tcgatgagca acaactacca cagtctgatg
    51181 ttctcgatac ttagacatac attctagaaa ccgagacttc atttccgtag ctgtctcata
    51241 ttgaatagga ctattaggaa gtaactcccc cctgttttct aaaaacagtc ttctagctgt
    51301 ttcaaagttt tctattcctg ttttatagac ctgccattca tgtaataaag gctctactct
    51361 taaaggaaga cccgtagcac agaccacata cgaagccgtt tctaaagctc ttgcgactgc
    51421 agaagatacg attatttcag ctgacgagag taaaggattt ttgctcaatt tctggacttg
    51481 ctgccgtccc atatcagaca agggtgccaa atctatccca aatcctatat aagaacgctc
    51541 ctctaactca cggtaatctg gctccccatg acgtacaaag ataatcttca ttctagtgcc
    51601 ctgtcgatcc aaatccacca gttcgaacgc catcagccgc atctccatct gcaattaaga
    51661 aagtagcaaa aacagcctgg acaatacgct ccccaacttc aagaacaacc tcttggtctg
    51721 tgatattctt catctgcgca aaaatatgcc cttcatttcc aggatttcca taataatccc
    51781 catcaatgac cccaactgag ttaattaaaa ccaagccctt cttacgagga tttgaagaac
    51841 gatcatagag gtagagaacc tcagtcggct gcatataagc cttaacccct gtcggaacca
    51901 agacaatctc tcctggcgca acaactgtac gcacagcaac ctttaagtcg taaccagccg
    51961 catgcgctgt ctcacgcttg ggcaataaat tttcatctgt aaaactcgaa accaattcaa
    52021 aaccacgaat tttcataatt ttctcttttc tattatcatt tattctagat tattctatct
    52081 tatttattcg gaaaaagcac gaaaaaaaga gcacacaatt caaatcgctt agggctgctg
    52141 gattcctccc ctgacccgct tcacgcagaa ctgttgctcc actatttatt atatcacatt
    52201 cctattcatt ttaaaagcaa aattattttt tccgtctatt tctaaaaaag tcctgcataa
    52261 tagctgcgca ttcatcttcc aaaattcccg tttcaacctc tacacgatgg ttaagacgct
    52321 catctgtcaa gatatcgtac aaacttccag cagcgccaaa tttctggttt ttagccccat
    52381 agaccacatt tggaatacgg gcaagcccaa tcgccccact acacatgaca caaggttcaa
    52441 tggtcacaaa aagtatgcaa tccagcaagc gccagctctc ctcactcaag ttcgcatcct
    52501 ctatagccat aatttccgca tgcataaccg ctcgctgtaa ttcctcacgc gcattatgcc
    52561 cacgaccaat gatttcccca tctttgacaa tcacacaacc aattggaatt tcatcgtgtt
    52621 caagagcaat ctcagcctct ctcaaagcct ccctcataaa gacttctttt tcttcaagcg
    52681 tataatacat ctcttttctc ttttcctact tatcgatttt attattatat catgaatccc
    52741 aacacaaaaa aagccaccga atgcggtgac tctataggga gattattatg aaaaagaaaa
    52801 gtttaggata tttgttacaa caagttagga ggtcttcttg taactgtcta tagtataccc
    52861 gacctatctt aaacaaatct taaaaatctc ttaggaccaa acactttcta aaatatttgt
    52921 ttgttcacga ccaggaccta ctgagaaagt agaaatacga acgccaacca attcactcac
    52981 acgacgaaca tagttacgcg cattctcagg aagatcttcc aaattgcgaa ctccggtaat
    53041 atcttctgac caacctggca actcttcata gataggcttg caacgtttca attgctcaag
    53101 actagctgga tagtagtcaa tacgttgacc gtcaagatca taggccacac agattttcac
    53161 agtatccaaa ccgctcaaaa catcaataga gttcaaagaa aggttagtaa taccagaaac
    53221 acgacggcta tgacgcatca caactgagtc aaaccaacct acacgacgtg gacgaccagt
    53281 tgttgtacca tactcatgac ccacttcacg gatacgttct cccacttcat caaacaactc
    53341 agttgggaaa ggaccatctc ctacacgact cgtataagct ttacatacac ctacaacctt
    53401 gtcaatcttg cttggaccga caccagaacc aattgtcaca ccaccagcta cagggtttga
    53461 tgacgtaaca aatggataag taccttggtc gatatctagc ataacacctt gtgcaccttc
    53521 aaaaagcaca cgtttgccat tatcaagcgc atcattcaag ataacagatg tatctatcac
    53581 gtatttcttg atttgttgac catattcgta atattcttca aaaatatcat cgaaaacaat
    53641 ctctttactg tcatacaatt tttcaaaaag acgattcttt tcagcaaggt tacgttctaa
    53701 acgctcacgg aaaatatctt tatctaaaag atctgcaata cgaattccaa cacgagcagc
    53761 cttgtccata taagctggac caattccctt aattgtcgta ccaatcttat tgtcgccctt
    53821 agcttcttct tgcaagcgat ccaactcgat atgataaggc aaaataacat gcgcacgatc
    53881 agaaatacgc aagttatcag ttgttacacc ttcctcatga agatagctca actcttttac
    53941 aagagattta ggatttacaa ccataccatt cccaatgaca gatatttttt cagggaagaa
    54001 aatcccagat ggaatcaagt gcaacttaaa tttcttaccg tcaatcacaa tcgtgtgacc
    54061 agcattatca ccaccttggt aacgtgcaat cacttctgca ttcgctgaaa ggaagtctgt
    54121 aatcttccct ttaccttcat caccccattg ggtacctaca acaacaactg aagtcataat
    54181 cttgtctgag ccctcaggct cttcctttct cacatacatg gcaggactct cacctgcaat
    54241 tatatcttac aatttattat aataaaaaat cgccttttta tcaagaagaa acaatagaaa
    54301 gatttgctat ttccaactat taaaaaatga tttagaaaaa ttactagcta tttactatta
    54361 tctttccata aaagagtaaa ttagttcgga aatttagtaa aattacctca acaagaaata
    54421 aaaccccgat tcattaccaa tttttcaaga tacaaacgat aagcaacacg ataatggtaa
    54481 acgataaaat ccctacgaca accaatgcca tatctcacta aataataaat taaaaattta
    54541 aaatgaacat gttcccagtc aaaattatca ccaaatgtag gaccatactc ttcttcaata
    54601 ctatcataga aattagccat ctgctcataa attttttgta acataatcaa atactccttt
    54661 tcttttttat aaacttattc taacaaaaaa ttttacacat tcactatcaa ttcctgaatt
    54721 gttaaaatac cagcctcaac aagataaaaa taggaaaagt tgacagaata gaaacaaatt
    54781 tgctacctaa atttcaaacg attaaagttc taaaaagacc gccttaaaac ttttgggtaa
    54841 atcctattag aactataata tttttatata ggtattatgg ttctgatttt ctagtataaa
    54901 aaaattcaaa ctagaatttt tcttagaaaa ggccgtttta agtgctatca ttgctcaaaa
    54961 atggaggtcg ctgagacttc tatcgtcaag aagaatcacc aaatccctcg tatcatcaac
    55021 caaaagattg ctcaaaagtt aattgaaaag atttctatga ccgatattgc tcatcagcta
    55081 tcagctggcc attttaactt caactgtcat tcgaaagctc aatgacttcc actttgagca
    55141 tgatttttcg cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac
    55201 tgtttcaatc gggagatgga gatgagcttt attgctcagg actttgataa gctcaatatc
    55261 ataactgttc ttgagagcag aacacaagcc atcatccgaa atcccatgga tacaaggcta
    55321 tcaagcgcta ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt
    55381 atcgccctac ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct
    55441 attccgaaaa cttgaaacac cactataatc tctatcagct cttgcttttc cacctctttt
    55501 tcagactctg tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt
    55561 accttattcc aaattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca
    55621 agcacaatgc ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg
    55681 tcctttctat atcttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc
    55741 tcgcctctaa tatagtcaat tgaaacaaga acaagacaaa agagcctcgt aaaaggtatt
    55801 gcaacgtggt aatacctttt tgaggttctt tttgatatga gcccatgttt tctcaatagg
    55861 attgtactca ggtgagtagg gaagaagagg taaaagttta tgcccaaact cttcacataa
    55921 aagttctagc ttacccattc tatggaatct tgcattgtcc ataatatagt agattgaaac
    55981 tagaatagta cacctctact tctaaaacat tgttagaatt cgattttact gtcctgatcg
    56041 atttgtccta ttcttatttc attttactat aacacgaaat atattattat tacataacaa
    56101 aaaagaggtc taaacctctt aactaaatta ctccgccagt aggactcgaa cctacgacat
    56161 catgattaac agtcatgcgc tactaccaac tgagctatgg cggatta
//
LOCUS       DAVFJR010000008        55722 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVFJR010000008 DAVFJR010000000
VERSION     DAVFJR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.008"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(128..1000)
                     /locus_tag="VU722_000678"
     CDS             complement(128..1000)
                     /locus_tag="VU722_000678"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU1771701.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1236..2546
                     /locus_tag="VU722_000679"
     CDS             1236..2546
                     /locus_tag="VU722_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU1771702.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2912..3106)
                     /locus_tag="VU722_000680"
     CDS             complement(2912..3106)
                     /locus_tag="VU722_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1771703.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(3566..4294)
                     /locus_tag="VU722_000681"
     CDS             complement(3566..4294)
                     /locus_tag="VU722_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1771704.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQYYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4452..5862
                     /locus_tag="VU722_000682"
                     /pseudo
     CDS             4452..5862
                     /locus_tag="VU722_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            5880..7175
                     /locus_tag="VU722_000683"
     CDS             5880..7175
                     /locus_tag="VU722_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU1771705.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYIFAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFTLMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            7180..7488
                     /locus_tag="VU722_000684"
     CDS             7180..7488
                     /locus_tag="VU722_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1771706.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTINMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            7485..7793
                     /locus_tag="VU722_000685"
     CDS             7485..7793
                     /locus_tag="VU722_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1771707.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VU722_000686"
                     /gene_synonym="adhC"
     CDS             complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VU722_000686"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU1771708.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWISQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGHNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVKKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTSFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(11665..12075)
                     /locus_tag="VU722_000687"
     CDS             complement(11665..12075)
                     /locus_tag="VU722_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771709.1"
                     /translation="MENLKSFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     ILKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(12062..12505)
                     /locus_tag="VU722_000688"
     CDS             complement(12062..12505)
                     /locus_tag="VU722_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU1771710.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYQRVQEGCKVWLERLEKESEDGKS"
     gene            complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VU722_000689"
     CDS             complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VU722_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU1771711.1"
                     /translation="MNPNYTFLIMLALMVGLIFFTQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VU722_000690"
     CDS             complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VU722_000690"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU1771712.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLR
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFVQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSIPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VU722_000691"
     CDS             complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VU722_000691"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU1771713.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKVTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(16282..17934)
                     /locus_tag="VU722_000692"
     CDS             complement(16282..17934)
                     /locus_tag="VU722_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1771714.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVV"
     gene            complement(18113..18817)
                     /locus_tag="VU722_000693"
     CDS             complement(18113..18817)
                     /locus_tag="VU722_000693"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU1771715.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(18819..19682)
                     /locus_tag="VU722_000694"
     CDS             complement(18819..19682)
                     /locus_tag="VU722_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU1771716.1"
                     /translation="MVRPIGIYEKAIPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKAPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(19686..20351)
                     /locus_tag="VU722_000695"
     CDS             complement(19686..20351)
                     /locus_tag="VU722_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU1771717.1"
                     /translation="MTKRIPNLQVALDYSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     IKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            complement(20368..20853)
                     /locus_tag="VU722_000696"
     CDS             complement(20368..20853)
                     /locus_tag="VU722_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1771718.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(20929..21210)
                     /locus_tag="VU722_000697"
     CDS             complement(20929..21210)
                     /locus_tag="VU722_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1771719.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(21233..22690)
                     /locus_tag="VU722_000698"
     CDS             complement(21233..22690)
                     /locus_tag="VU722_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1771720.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKSTVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(22821..23444)
                     /locus_tag="VU722_000699"
     CDS             complement(22821..23444)
                     /locus_tag="VU722_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU1771721.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(23495..24481)
                     /locus_tag="VU722_000700"
     CDS             complement(23495..24481)
                     /locus_tag="VU722_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU1771722.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(24500..25324)
                     /locus_tag="VU722_000701"
     CDS             complement(24500..25324)
                     /locus_tag="VU722_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU1771723.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQTQKDLENRKRKAKKKAQKTK"
     gene            complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VU722_000702"
     CDS             complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VU722_000702"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU1771724.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGGLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(25819..27009)
                     /locus_tag="VU722_000703"
     CDS             complement(25819..27009)
                     /locus_tag="VU722_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU1771725.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPKKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEVAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(27060..28013)
                     /locus_tag="VU722_000704"
     CDS             complement(27060..28013)
                     /locus_tag="VU722_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1771726.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(28074..28661)
                     /locus_tag="VU722_000705"
                     /pseudo
     CDS             complement(28074..28661)
                     /locus_tag="VU722_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(28798..29211)
                     /locus_tag="VU722_000706"
     CDS             complement(28798..29211)
                     /locus_tag="VU722_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU1771727.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(29189..29650)
                     /locus_tag="VU722_000707"
     CDS             complement(29189..29650)
                     /locus_tag="VU722_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU1771728.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVESNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(29613..29873)
                     /locus_tag="VU722_000708"
     CDS             complement(29613..29873)
                     /locus_tag="VU722_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771729.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(29878..30282)
                     /locus_tag="VU722_000709"
     CDS             complement(29878..30282)
                     /locus_tag="VU722_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU1771730.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQMISNGGQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VU722_000710"
     CDS             complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VU722_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU1771731.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVYD"
     gene            complement(30603..31619)
                     /locus_tag="VU722_000711"
     CDS             complement(30603..31619)
                     /locus_tag="VU722_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU1771732.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGESFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(31567..32508)
                     /locus_tag="VU722_000712"
     CDS             complement(31567..32508)
                     /locus_tag="VU722_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU1771733.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(32584..32949)
                     /locus_tag="VU722_000713"
     CDS             complement(32584..32949)
                     /locus_tag="VU722_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU1771734.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(33100..34157)
                     /locus_tag="VU722_000714"
                     /pseudo
     CDS             complement(33100..34157)
                     /locus_tag="VU722_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VU722_000715"
     CDS             complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VU722_000715"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU1771735.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHAEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(35624..37441)
                     /locus_tag="VU722_000716"
     CDS             complement(35624..37441)
                     /locus_tag="VU722_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU1771736.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFLSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLVALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYTHTILVASTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(37542..38684)
                     /gene="tgt"
                     /locus_tag="VU722_000717"
     CDS             complement(37542..38684)
                     /gene="tgt"
                     /locus_tag="VU722_000717"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU1771737.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            38814..39671
                     /locus_tag="VU722_000718"
     CDS             38814..39671
                     /locus_tag="VU722_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU1771738.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLALSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCNKIMFYRA
                     VLARKRPKA"
     gene            complement(39699..40342)
                     /gene="pcp"
                     /locus_tag="VU722_000719"
                     /pseudo
     CDS             complement(39699..40342)
                     /gene="pcp"
                     /locus_tag="VU722_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(40345..40755)
                     /locus_tag="VU722_000720"
                     /pseudo
     CDS             complement(40345..40755)
                     /locus_tag="VU722_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(40957..42099)
                     /locus_tag="VU722_000721"
     CDS             complement(40957..42099)
                     /locus_tag="VU722_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU1771739.1"
                     /translation="MNKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSVVAEEAPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(42229..42885)
                     /locus_tag="VU722_000722"
     CDS             complement(42229..42885)
                     /locus_tag="VU722_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1771740.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSMAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLNKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGKHRIQALADISRIFEAERQKDCVSFVTET
                     "
     gene            complement(42889..44169)
                     /locus_tag="VU722_000723"
     CDS             complement(42889..44169)
                     /locus_tag="VU722_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU1771741.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTSMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            complement(44230..45714)
                     /locus_tag="VU722_000724"
     CDS             complement(44230..45714)
                     /locus_tag="VU722_000724"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU1771742.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELNYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCESYS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(45790..47067)
                     /locus_tag="VU722_000725"
     CDS             complement(45790..47067)
                     /locus_tag="VU722_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU1771743.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(47329..47805)
                     /locus_tag="VU722_000726"
     CDS             complement(47329..47805)
                     /locus_tag="VU722_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771744.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYSFSEADIKE
                     LFGALEQKGEEIKEFFTSPITIKTVNLKQEFNYSSTDTSNDKEVYFKKLSTARVEKIF
                     SLMNLLTNLSNKSNYSYNDWEIEELFTAYDEEVKKCKVFFEEKRTVFKYSEQAIKY"
     gene            47959..48240
                     /locus_tag="VU722_000727"
     CDS             47959..48240
                     /locus_tag="VU722_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771745.1"
                     /translation="MFKELIEFVNSSTEGQFKAFQVKANAITGDVIISQNVTPITDAL
                     KNRLGLKTVQTSLARKLAYASTRRHYKDGTTMMEDILAGKTRRHANSYI"
     gene            48302..48544
                     /locus_tag="VU722_000728"
     CDS             48302..48544
                     /locus_tag="VU722_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771746.1"
                     /translation="MKSLYKYLFYLFFIGFAGTLCYVLLLTNAFSPIFEAATILMEII
                     VVIFLIICIDLIASPTGSAEENIKNENVKSNNPCEE"
     gene            48507..49871
                     /locus_tag="VU722_000729"
     CDS             48507..49871
                     /locus_tag="VU722_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEU1771747.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNITITRLSIQVFLFLLLVSSWLA
                     AIPFIARLVFSMFFISLLFLVERFFHSDVIEKLRNKLNIREALFYMLISLTLYDDIDN
                     EVVDTAVLYFDVSENDKVIICVPLFGNRYLKTLKNLEEYLCPTLGLSLIFKKEEIDKI
                     VYVLGKIEEIEQYVFNTNTLTREFFKDIPSPIIKLSNTQQFSLKSNTNIGIYGRTGTG
                     KTIALQWYLFNALAKGCGTVDGTYLGIVDGKGADLYALGKLLEEEIGNQVTVGTSPTS
                     LAKLSREFVEIMNERFEVIKQNSSLNADAYDLGMIPNFLFVDELASIRDSCCGSSKQA
                     KELWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGGPGADR
                     LKMAFSMCELENVPTVSDRKGEALFYADGLNSVEPVLTIVPFVDVKTKQEFLQIVKNI
                     LPNY"
     gene            49969..50283
                     /locus_tag="VU722_000730"
     CDS             49969..50283
                     /locus_tag="VU722_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771748.1"
                     /translation="MKLNDFLKPELLGNRFFAVKGYTEVLDRETNKPVALRLNVSIQD
                     ENSDFFMEMIQVKINTLSPTASVQEMANNKTCPVSLKDLNVGQFNGNLWFACSDVLPV
                     TK"
     gene            50317..50706
                     /locus_tag="VU722_000731"
     CDS             50317..50706
                     /locus_tag="VU722_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771749.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            50873..51640
                     /locus_tag="VU722_000732"
     CDS             50873..51640
                     /locus_tag="VU722_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU1771750.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPRL"
     gene            51826..52605
                     /locus_tag="VU722_000733"
     CDS             51826..52605
                     /locus_tag="VU722_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEU1771751.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTDIKSKEKLQR
                     RTFDELTPEEQEQRLERMKKTRLEAKWNLLRLVDCNYDDNTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYLTVLEKQKRGAWHAHILLFSVPYVPHRQLLELW
                     EHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDRFY
                     TYEDFNYDSSVVLYETEYISKVYKDGQYFDNHVKYKKIKLD"
     gene            52622..52825
                     /locus_tag="VU722_000734"
     CDS             52622..52825
                     /locus_tag="VU722_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEU1771752.1"
                     /translation="MIATVTKNDLVALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIVSELLGFDVQNSTLKE"
     gene            52829..53962
                     /locus_tag="VU722_000735"
     CDS             52829..53962
                     /locus_tag="VU722_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU1771753.1"
                     /translation="MAIRKGKDGNWIVDISNGFDPITLKQRRIVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     YNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYTSN
                     PANLIKKLPIEKTKMQFWTVKEFQHFLTLFETEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFTSNTIHITKSVYVNKGISHVSTTKTKAGTRRIIINKKLSHELQQWQQKQKHL
                     LEQFTSDSMTLQVFQGSPITITKNAVEKQYKKILERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            54003..54440
                     /locus_tag="VU722_000736"
     CDS             54003..54440
                     /locus_tag="VU722_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU1771754.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVDSFVATDEE
                     KAAAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            54656..54892
                     /locus_tag="VU722_000737"
     CDS             54656..54892
                     /locus_tag="VU722_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU1771755.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAFIEKI
                     EDMYDIKVADEAYKKWVECSKKSISHEEMMRRYG"
     gene            54885..55616
                     /locus_tag="VU722_000738"
     CDS             54885..55616
                     /locus_tag="VU722_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU1771756.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEKL
                     NYIFKSNANNFETDVRNEIKNNIKFNPFINWFKKRYRDERYYETETQIFVHAGIDEEA
                     EKLWKELTSSEIFTNKFLITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
BASE COUNT        17119 a        11632 c         9800 g        17171 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttga agaggcgttt
       61 aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt
      121 ttacaactta gacatcaagg taggttaacc ccttcatgga aaaatcaaga ctcttagcac
      181 tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa cggctaatag
      241 tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt agggtaatgg
      301 cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcagca cccgccgccg
      361 cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc acaaaaggag
      421 cataggcacg cgcttgagca attgcctttt gaacactacc tactgccgca atgtgattgt
      481 cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca
      541 cggcatattt ctcaaaaaga cgtaaattag gagtagtttt tcgagtatca aataccttaa
      601 tgcaatcatc gcctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat
      661 gttgtaaaaa attcaaggca acgcgttcac atgttaagag acttctcacc gagcctatga
      721 tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga tgaggattct
      781 ggaaggtcac ctcggcatca aatagggtaa aaaccctttg aaaaacggtt agtcccgcta
      841 aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg
      901 cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat
      961 ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta
     1021 atatcacttg taagcactag aggcaattac tattaacttc cataggaaat cacaagcctg
     1081 aatacctcat ttttaattct aacaagtgtc aatacaattg tcaagacaat tgtatttttt
     1141 tgtgtataat agtcaagtac caataggaaa caggtggtct tttgagcgcc aaaattgcca
     1201 acctatttcc atattctaac tgaaaggaca attcaatgat tcatttaata atgattagcg
     1261 ccattgctct agccattgga attggttacc gcaccaaaat caatattggc ctgctggcta
     1321 ttgctttttc ttacctcatc gcaaccactc tcatgggatt aagccccaaa gaacttcttc
     1381 atttttggcc aacctcactc ttttttacca tttttagcgt ctctctcttt tataacgttg
     1441 caacaactaa cggtactctt gatgttttgg ctcaacacat tctctaccgc acacgcaccc
     1501 accctaacgc cctctacatg attttatacc tgatggcaac ccttttgtct gctttaggtg
     1561 ctggattttt cactactatg gccgtttgct gtcctctagc gattaccctc tgtcaaaaag
     1621 cggacaaaca ccctttgatt ggagctcaag ccgtcaattg gggagcttca ggaggggcta
     1681 atttgataac cagtagctca ggcattgtct ttcaaggcct gtttaagcaa atgggatggg
     1741 aagagcaagc tttttcactt ggcaatcata tctttatcgt cagcattatc tacccactca
     1801 tcgtcttgct tttattatcc tgttacagtc actatagtaa gggaagaaca aactcatcct
     1861 tgactattga ccaaccacca ctcctcagca aggttcaaag acaaaccacc ttgctcatga
     1921 tcagcagcat ggttttggtt tggctttttc ccttgttgca tctcattttc ccaaacatcg
     1981 cctggatagc tacttatcga aaaacatttg atattggctt tgtctcaata ctcatggtct
     2041 gcctcgcctt aaggctcaaa ttagggaagc aagaagccat tttggctaaa gttccctggg
     2101 ctacaattat catgctctgc ggcatgagct tactaatgtc tctagcggtc aagtcaggtt
     2161 tagtcacact gatagggcac ctcatgacaa catccattcc tcatttctgg ttacctctgt
     2221 tcttttgtgt gatagccggg gtgatgtcac tctttagttc caccctatcc gttgtagctc
     2281 cagccctctt tcccatcatt gctatcatca gtgctcaaaa tcctcagatt gatattcact
     2341 tactcacaac agccaccgtt attggcgctc tatctactaa tatctcaccc ttttcatcag
     2401 ctggttctct cattcaactc tcacttccca atatagagga acgcggcctt gccttcaaaa
     2461 agcaaattat tctgggtgtc cccatcagct taagtttggg actcttgacc acctggattc
     2521 tcatccttct agcttcctta agttagattc attatctaac ttaagggtgg acttggtata
     2581 ataaagtaga cacaaaatta agtggaaacg aggaaaagtc attatgccaa gaaaaacctt
     2641 tgataaagcc ttcaaactct ctgctgtaaa cctcatcctg taaaaataat tagttcaact
     2701 ttaaaaattc atcccaatag tctttatcga tggattcaag aatatgaaaa atatgaagaa
     2761 agtgcgttcc caggacatgg gagcgcactt cgtcatactc aatttgagat gtagtgaaat
     2821 gaaataagaa caggacaaat agatcaggat agtcaaatcg atttctaaca atattttata
     2881 agtagatgtg tactattcta gtttcaatct actatagtaa agttgacttt cctgtaccat
     2941 ttttaccagt aattaatgtc acgtctgaac tcgaagtatc aaaagaaata ttatcaaaca
     3001 atatacgatg atccacccta tacgaaatat tttctacttt cattttttct ccttttgaac
     3061 taatagcaaa agaaacagtt ctgttttcat actctttccc cttcatctat attattcgta
     3121 atgaaaaata aaaaaataaa atttttttaa atgattatga ttcagaattt gtttaatata
     3181 ttaaaataat atataagcaa ataaattggg agattgaaat tcatttctag caatttgtta
     3241 gaagtcacag tctactattc taaccacagt atactatatg tgttacaaga aaagactcaa
     3301 aaacttctcg tcagtgtaag aatgtttgaa acactattta aaactaaata actataagaa
     3361 gtagatcagg tgaacaattt cagtacctac tctataagct atacgaagat atttttcaac
     3421 atgatggata aaacgatcac tcttttaaag ccatcttatt tagaaaagag aaaccattta
     3481 agcatagatg ggaccttctt gccctgtttt aaatttttct taaactagag tctgtaaaag
     3541 attggcttca ttttcacatt ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt
     3601 caaataaatc atagcgatga cgactaatcg agtactcaaa cggagttccg ttatccaaat
     3661 aagccacttg ttctacttca aataccggtt ccgttggaag gagctgcaag taatattgct
     3721 cattttctga actagaagaa gctcgtaaga tttttgtagc actggcaata tgcaatccta
     3781 actttccttc aatgtaattg taaatcgatt tttgtaaaat atcttcagta atacctggaa
     3841 taacatcggt actcatataa gtttgttcca gaacataagg tttaccgtca ataatacgca
     3901 ggcggtaaat attataaact ggactctgca aagcgacctg tagtttttct gctaaaaatt
     3961 catttgcaaa ttctaatttg aagtgaataa tcctcgagtc aattgtagaa tgagcatctt
     4021 cagatatttt tgtcagtccc cggatatctc tttctggaac gattaatttt ctttttgagc
     4081 tgccacgaga gagaacaaag gttccctgcc cacgttttct aaaaattaag ccctcagaaa
     4141 ctaacaagtc taaagctttt ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg
     4201 tcatttcatc aggcaattgt tcgttcatgg tatatttatt acaaagaatc ttttcacgaa
     4261 tctcattgta aataaataaa tattttgtac tcatttaatc tggttctctc tataatattc
     4321 taatagtagt ataacaaagt tcaagaaatg aggcaaacac aagatatgta tcaacaattt
     4381 ttaaaaatgt ctagacaaat tttaaaatta tgctatactt tatgtatagg ataatagaaa
     4441 ggaggttgag catgaaaaaa aagttagtat ttcctaatct gttttggtgg ggagctgctt
     4501 ctagcggacc tcagacagaa ggtcaatatg gaaaagtaca tgaaaatgtg atggactact
     4561 ggttcaaaac gcatccagaa gattttttcg ataatgtcgg acctcttgta gccagtaact
     4621 tttttcatac ttacaccgaa gatttccact tgatgaagga aattggagtt aattctttcc
     4681 gcacttccat ccaatggagt cgactcatca agaatttaga gacaggtgag cctgatccaa
     4741 aaagtattgc tttctacaat gccatcattg aagaagctaa aaagaaccag atggatcttg
     4801 tgatgaattt acatcatttt gatttaccag tggaacttct tcaaaaatac ggtggttggg
     4861 aaagcaaaca tgtagtggag ttattcgtga agtttgccaa gactgctttc acatgctttg
     4921 gagataaggt tcattactgg acaactttca atgagccaat ggtcattcca gaagcaggat
     4981 acttatatgc tttccattat ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca
     5041 tctataatct aaaccttgct agtgcaaaag tgattcaact atatcgctca ttaggacttg
     5101 atggaaagat tgggattatt ttaaacttga cacctgctta tccaagaagt aattctccag
     5161 aagacttaga agcaagtcga tttacagaag acttctttaa caaagtcttc ttgaatccag
     5221 ctattaaaag gaactttccc agaaagattg gtaaaacagc tagagagaga tggcgtgtta
     5281 tggagtcata ccgaaaaaga gcttcaactg atgaaatcaa atacggttga ttttcttgga
     5341 gtaaactact accatccaaa acgtgttcaa gcacaagcaa atcctgagga atatcagacg
     5401 ccctggatgc cagaccaata cttcaaagag tatgaatggc cggagcgtcg catgaatcca
     5461 tatcgtggtt gggaaatttt tccgaaagcc atttatgata ttgctatgat tgtgaaggaa
     5521 gaatatgata atattccatg gtttatcagt gaaaacggaa tgggtgttga aaacgaagca
     5581 cggtttatcg gtgaaaatgg agttatcgat gacgtgtatc gtattgaatt ttatgaagaa
     5641 catttaagat ggctacataa agccattgaa gagggaagtc actgttttgg ataccacgct
     5701 tggaccgcat ttgattactg gtcttggaat aatgcatata agaatcgtta cggatttatc
     5761 tccgttgatt tagaaacgca aaagagaacc atcaagagct caggaagatg gtatcgcaaa
     5821 gtaagtgaca ataacggttt tgaagtagaa attgaggagt aaagagagga gatattcaga
     5881 tgaaaaactc aaaatttata gatcaatttg ccacctttgc tggtaaacta gggaaccaaa
     5941 ttcatttaaa aaccctaaga gatgcattcg taacagtaat gccattatat atttttgcag
     6001 gtttaatcgt tcttttgaac aacacggtat ttaagtggat tttccaaggg gatacattaa
     6061 caagattcca atattgggga ataacaattg caaacggtac tttaagtatt tcaggtatga
     6121 ttattgctgt aatggttggt tatttcttag ctaaaaacag agatttcgaa aacccgttag
     6181 cagcatcaat gctatcatta gtttctttaa ttgtgatgat gccaaataca gtttctgtag
     6241 ttcctgacgg agcaaaagat gcggtaaaca tttcaggtgt tctttcattc aacaacacag
     6301 gtacaggcgc aatgttcgcc ggggttatcg tagcgattat tgcaacagaa ttattcattg
     6361 aattatcaaa cgttaaagct ttacaaatga accttggtga aaatattcca ccagctgtta
     6421 gtagatcatt tagcgtatta cttccagtca tgaccgttat ctccttattt ggggttgttt
     6481 cagcattatt attcaatata actggaatga acttaatctc aatcattaca atctttattc
     6541 aagaaccaat tcgtcatatt ggtacaagct taatcggggt cattattatt tactctttag
     6601 gaaatatgtt atggctattt ggtattcacc aagcagttat ttacagtgcc atcctagaac
     6661 cattactatt aattaacatt actgaaaaca tcactgcagc aaataatgga caagccattc
     6721 cacacatcat caacctatca caaatacaaa cattcacttt aatgggtggt agtggatcta
     6781 cattatgttt attaatagca acattcttag tgagtcgcaa tgctgtctct aaaaacgtgg
     6841 ctaaattatc ttttggacct ggtatcttca atatcaatga accagtatta ttcggttacc
     6901 caatcgttta taacatttca ttagctattc catttatcac agttccagtc cttggtattt
     6961 taatcagcta cttagcaaca gttacaggat tcatgagtcc tgcatttata caagttcctt
     7021 ggactacacc agtattctta aatgcatggt tagcaacagc aggggacgtg agagcagttc
     7081 tagttcaatt catcatcttt gcacttggag ttcttctata cattccattt atcaaagtta
     7141 atgacaaagt tgttgaacaa gaaatggaag gttaagatta tgaaacaaat tttattagta
     7201 tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag tgcgactgaa
     7261 cgtgggattg aaatttctat ccaagcaaaa tcaatgacag aagctaaaaa gaatatccat
     7321 gaagcagatg tcattctaat tgggccacaa attcgttatg agttacttgc tgtgaaagaa
     7381 attgcaggaa atatccctgt agataccatt aatatgcggg attacggaat gatgaatgga
     7441 gcaaaagttc tggaacaagc acttgcatgg ataggagaaa taagatgaca gaagaaatgg
     7501 aatatatctg ttttcagctc attgccaata gtggagcagc caaatcatcc tttattgaag
     7561 ccatccaact agctaaggca ggaaatttaa aagaagcgaa aattaaagtt gaagaagcgg
     7621 aagactcctt agtagaagcg cacaagattc actctaatct catacaaaaa gaagctactg
     7681 gagaaaaaat aggattctcc ttgctattta tgcatgcaga agaccaaatg gcttcaacgg
     7741 agattattca gttgctatct aaagaattca tcgatctcta tcaaaataaa taggaacact
     7801 gtcgttccca tctgtcttta ttaatgacgg ctacattata ggaacctcca aaagttggac
     7861 aaaatgattg aaaggattgg atcctgcatt acacaagatc caatcctttt cttttactct
     7921 agtttttata atatgttgaa tctagaatag tccactgtag tttctaaaaa attgctggaa
     7981 atggatgtta agctccaatt tatttgttta tatcttattt cagtttacta tactagctta
     8041 ttattctagt gaaaaattga atgagccact atttatttaa tatgtatgat gagggaatga
     8101 ctcaaaaact tcttgtcgat ataagaatat ctgagatagt attttaaaac gaaaggacta
     8161 taaaagctca tttccttcgc gcttatttta tagagatcta tcattatact ctttagaaat
     8221 caaaaagcaa cacaccttgt catcgttttc tcgttttctc gtttgctctt tgattttaat
     8281 tgggccttag taaatactac tcttaaatta aactatagtg aattgaaata agatgtgaac
     8341 aactctatca ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat
     8401 tttagattca ttttattata ctatattttt tatatagtat agtaaaatga aataagaata
     8461 gaataaatcg atcaggacag tcaaatcgaa ttctaacaat gttttagaag cagatgtgta
     8521 ctattctagt ttcaacctac tatatatttt gtttctattc tagtttttca aaaagggcaa
     8581 aaaggcctca acatcataaa aaggcatcct atcaggtatt caaaaacctt gataggatgc
     8641 cttttatcat agaaaaatta ctggttcttt ccctcaaatt gagtttttgt cttgcttcta
     8701 gactgataaa caattattta cggcgccctg gtctttcttt gtagccatag tatgcatctt
     8761 cgatgatttc ttgcatatgg tctaccattg gaagacgtgg gttagctggt gaacattggt
     8821 cttcataagc caggaaggct aattcacgag aatgttcttt ccattctttt tcgtcaattc
     8881 cttggtctct aaaattcatt tggatcccaa tacgttcacc gagttcgtag acagcttttg
     8941 cgtaagattc aaccccttct tctggagtag aagctggaag tccaagcatg cgtgcgatat
     9001 cttggtattt ttcatctgca cggtagtagt tgtacttagg ccatgttgct gtcttagctg
     9061 gacgtgtacc gttgtaacgg ataacgtacg gaagcaagat ggcatttgta cgtccgtgaa
     9121 ctgtgtggaa ttgcgcacca atcttatggg ccattgagtg agaaatacct aggaaggcat
     9181 tggcaaaggc cataccagcg attgttgaag cgttatgcat tttctcacgt gagtggaagt
     9241 ctgcattctt aactgagctt tcgagatttt caaagaccaa tttaatggct tgaagtgcta
     9301 aaccatcagt gtagtcacta gccatttgtg atacgtatgc ttctgtcgcg tgagtcaata
     9361 cgtccatacc agtatcagca gcaacaaatc ctggaactgt caataccaaa gcaggatcta
     9421 cgattgccac agttggtgtc aatgagtagt cagcgattgg gtatttacgg ttgtttgctt
     9481 tatcagagat aacggcaaat gatgttactt cagatcctgt accagatgta gttggaatcg
     9541 cgatgaattt agtcttctta ccaagcaatg ggaacttgaa ggcacgttta cggatatcca
     9601 tgaatttttt gacaaggtca cggaagtcca cttctggttg ctcgtagaag agccacatta
     9661 ctttggcagc atccattgga gacccaccac cgagtgcgat gatggtatct ggtttgaagg
     9721 cacgcataat ctcagtacca cggtttacag ttgtgatatc tggatccggt tctacatccg
     9781 caaagatttg gtaaacaacc ttattgcgac gaaggtccag ttgttcgatg atacgatcaa
     9841 ggaaaccaag ctctaccatg gcatggtcag taacgatcat gacacgttca acgtcacgac
     9901 atttttgaag gtattgaatt gaatcacgtt caaagtatgt ttttgaagga agtttcatcc
     9961 attgcatgtt atttctccgt cttccgactt ttttgatatt caagaggtta atggcactaa
    10021 cgttatcccc aactgagttg tgtccgtaag aaccacatcc aagtgtcaat gatggcaaga
    10081 aggcattgta aacgtccccg ataccaccaa aagtagaagg tgagttacag ataacacgaa
    10141 tagctttaac agctttacca aattctttag tcaattcttc gtcagctgtg tggatagctg
    10201 ctgagtgtcc aagaccgtta aattcaacca tttgacgagc cttagtaata ccatcttcac
    10261 ggctttcaga tttcaaaact gcgataactg gtgacaattt ttcacgagtc aatggctcat
    10321 tttcgccaac ttctttacat tctgcagcaa gaatgtttgt tccttctgga actgtaaatc
    10381 ctgcttgttc tgcaatccaa gttgctggtt taccaacgat gtcagcgttc aattttgcac
    10441 cagcacagtt tttgctgttt gctttgacgc cgaagcagaa ctcttcaaga agagcttttt
    10501 cttttttgtt tacaaagtaa gtgtggtaag atttgaactc tgctacaaat tcatcgtaaa
    10561 tttctttatc aatgataact gcttgttcag atgcacagac cataccgtta tcaaatgatt
    10621 tagacatgac gatatcgtgt gctgcttgac gaatgtttgc tgatttttca acataagctg
    10681 gaacgtttcc ggcacctact ccaagagctg gtttaccaca tgaataagcc gccttaacca
    10741 tggcattacc acctgttgca aggattgtcg caacaccttc gtggttcata agggcacttg
    10801 ttgcttccat agatggttga ctaatccatt gcacacagtt ttcaggagca ccagctgcga
    10861 tagctgcatc gcggacgata cgagctgcat gagcagatga ttcttgtgct gatggatgga
    10921 aggcaaagac gattgggtta cgtgtcttca atgaaatcaa tgatttgaag attgctgttg
    10981 atgttgggtt tgttgttgga gtaataccac aaacaacacc aactggttca gcaataagag
    11041 tcaatcctgt tacatcgtct tcttcgataa cgccaactgt cttagtgtgg cgcatgttgt
    11101 ttactacgtg ttcacaggca aacaagttct tagttgcttt atcttcaaat acaccacgtc
    11161 ctgtttcttc aaaggcatgt aaagccaatt ctccgtgggc atccaaagct gctactgatg
    11221 ctttggcaac gatgtagtca acttgctctt gatccaattt acgcatttct tcaagggcaa
    11281 ctagagcttt ttgaaccaac tcatctacgt gtttttcagc aacgagtttc ttttcctctg
    11341 gtgtcacagt ttttttatca gccatatttt cctccatagc tttcaaggat cgatatcctt
    11401 tgttaatttt ttcacaagtt tattataacg cattatttca actttgtaaa cagtttcata
    11461 aacatttcac aaagaatttt taaactcttg tgaaactttt ctcattttct tttcttatca
    11521 ggttttatct ttgaagtttg tgaaatttat ttcaaatatt ttttatttca caaacttgct
    11581 tggaagaggg atttggaaag aaaaggattt gcaagtaagc gcttacttaa aacttctaac
    11641 aatacctcct ttgataagga ggctttattt ttgttgaaaa acgccttgtt taaaagtccc
    11701 ttcataaaca acttcttgtt ctgttgttag ttttcctttt ccttcagcct gaccatttac
    11761 aaaatcacct tcgtaggtcc aaccttcttt agattgaaaa gtaccttttc cattgaaggc
    11821 tccattgttg aagccacctg tatattggtc tccattttgg aaggtaatgg taccttgtcc
    11881 attcatttta ccacggacaa gactgccgtc gtaaacaatc gttccattat cgagttttag
    11941 aatacctttt ccgggaatat ttagaaaaaa gacgagtaca gcacaaaaaa caatggtaac
    12001 tactgctaaa agctctaaac gtggacgagt cagatagaca cgatactttt cataaaaact
    12061 cttaagattt tccatcttca ctctcctttt ctaaacgttc taaccaaact ttacaaccct
    12121 cctggacacg ctgataggtt tcctcaaaat ctcctgtata ccaaggatct ggaacacttt
    12181 cagatgaaaa tgagtaaatc ttatcttgac agtctactgg acacatctga cgtaagtcgg
    12241 aaacatttga agcgtccatt ccgataatat aatcaaaggc ttcaaaatct tccttactaa
    12301 tctgaagcga tgtcttgttc ttgtcataag gaatctcata ctgttgaaaa attccctgag
    12361 tccccttatg aatcggattg ccatgttccc aagaggaagt tgctcgactt tggatttcgt
    12421 agttatctgt cattgatttc ataacaaact cggccatagg gctacggcaa atatttccta
    12481 gacagacaaa gactaatttt ttcatcccat ttcctttctt ttatagaaaa acgggagttc
    12541 gtgatcccgt cttatttttc aattgcgcct tctagtgaag ctgtttcttt cagcggtaat
    12601 actgtcttga tagcagctag ttcaaaagtc aagtaaactc catctacgtc aagaactatt
    12661 gttcccttct ccgtatctac ttcatcgact gttccataaa gtccaccgat tgtaatcact
    12721 tcatagcctt tttgtagttt atttaagctt tccatacgtt tttgtgcttg tttcttttga
    12781 gagcgttgcg taaagaatat caagcccacc ataagggcta gcatgattaa aaatgtataa
    12841 tttggattca ttgtcttctc ctttgtcttt tacataggac tactatatca aatttcggct
    12901 acttttacaa gattgtacct tacttttctg gtaagaaaaa ccagagcttg cgccctgatt
    12961 tttaggatta tttcaagttt cgaacaactt ttacaagatt ttctacagta aagccatatt
    13021 ctgccaatac ttttggtgct ggggcagagg ctccgaaggt atcaatacct agaacggcac
    13081 catcgagacc aacatatttg taccagtttt gacttgcacc catttcaatt gcaacacgac
    13141 ggcggactgc atttggaaga atttcttcct tgtaagctgc atcttgttta tcaaagacat
    13201 ctgtagatgg aatgctgact acgcggattt tttcgccttg actagccaat tctttagcag
    13261 ctgagacagc aagattaacc tctgaacctg tcgcaatcaa gatggtatca aagtcggctg
    13321 cattttcata tacaacataa gcacctttag caaccttgtc gaagtctgtt ccatcttcaa
    13381 cagtcaagtt ttgacgtgtc aagacaaggg cagttggtgt tttctcactt gtcactgcaa
    13441 ggtaccaagc tgcttgagtt tcacgcgcat ctgctggacg gaaaacattt agatttggca
    13501 tagcacgaag acctgctaaa tgctcaactg gttcgtgagt cggaccatct tccccaactg
    13561 cgattgaatc atgggtaaag acataagtca caggaagtcc ttgtaaggct gacaagcgga
    13621 cagctgcctt cacatagtca gagaagacga agaaagttcc accgtataca cgaagtccac
    13681 catgaagggc catcccgttc aagattgttc ccattgcaaa ttcacgaaca ccaaactgaa
    13741 tgttacgatt caagcgattg gcatcgtctt gaagtccatc cgtcttgata taagtcatgt
    13801 ttgagtgagc aaggtcagct gatccaccta ggaaggttgg taatttagct gccacaacat
    13861 tcaaggcatc ttgacttgaa ttacgagttg cttgagaaaa accattttct aaagctggga
    13921 agtctgctgg agtcacttcg actggatcac gtccgtcgat gatggcttct acttctgcag
    13981 ccagttccgg atgagcttct ttataatctg caactaattt agtccaagct tgataagctg
    14041 atgcgccacg gtctgcaaca tgttctttga aatcagcata tacttgttct ggaatttcaa
    14101 atggttcgta gtcccaaccg agggcttgac gagttgatgc agtttcatct gctccaagag
    14161 gggcgccgtg tacagcatta gttccttgtt tgtttggaga accgtatcca ataaccgtct
    14221 tcacttcaat caaagatggc ttgcctgaag cttttgctgt ttcgatagca gcatggattg
    14281 cttccaagtc tgttccattt tcaaccaagg cagtatgcca accgtaggca ttgtaacggt
    14341 cacgaacact ttctgtaaag gaatcctttg tctcaccatc caagttgata tcatttgaat
    14401 cataaagaac aaccaactta tcaagttttt gcaagcctgc gtatgaagct gcctcgcttg
    14461 agacaccttc catcaagtct ccgtctccac agataacgta agtatagtgg tcaaagatat
    14521 tgtagccttc acggttatat ttagctgcca agaaacgttc tgcttggaca aaaccagtag
    14581 cagttgaaat cccttgccct agaggacctg tcgtagcatc aatccctgcc gtatgaccaa
    14641 attctgggtg acctggtgtt tttgaacccc attgacggaa gctcttaatc tcatccatgc
    14701 tgacatcttc aaaaccagaa aggtgaagaa gagcataaag gagcattgaa ccatgaccag
    14761 ctgaaagaat aaaacggtca cggttaatcc agtttggttg agctggattg atacgaagtt
    14821 gttttgtaaa gaggctgtaa gccatcggag ccgctcccat aaccacacct gggtgacctg
    14881 agttggcttt gttgatagcg tcaataccta ggaaacgaat tgcattaaca gatagatttg
    14941 acatagaatt tcctttctat ttgaggtgat tattgaatca cacattctat tttactatta
    15001 tatgaaaatt atccgtatgt tgcaacatac ggataacctc caaagaatat ttttatatta
    15061 taacaaagct ttaaattgaa tgttagagtc ttgttcaaaa caatcatcaa aaccacgtgg
    15121 atgatggtat tctactaagt gttgatcttg aggataagtg tacttaccgc caacttccca
    15181 gataaatgga tggaaatcgt attgcaagcg atcttttcgc attttccaaa gttctagaat
    15241 ctcattagta gaagccatga agttagacca aatatcatag tgaactggga taatgacttt
    15301 ggtacgcaga ttttctgcca tacgaagaag gtcgatagat gtcactttgt cttggatacc
    15361 taccggattt tcaccatagt tattcaaagc aacatcaatt ttaaagtctt taccatgttt
    15421 tgcaaaatag tttgagaagt gagaatctgc accgtgatag atggttccac ctggtgtttc
    15481 aaagatatag ttaacagcct tttgagccat ttcctcatct gtaacagcta agccagcaag
    15541 ttcaccgcct gtctcatcag caccgttcac tgggagagtt accaagcaag tacggtcaaa
    15601 tgattctact gcatgaatct tcatatcttt taattcgata gtgtcacctg gtttaacaac
    15661 gatgatacgt tcttttggaa caccccatcc ttcccagatt cgtccacagt ggtaaggacc
    15721 gataaactta acatgctcta acttaggatt gttgagaatt gctgcagctg tgtatgggtc
    15781 gatatgatca ctgtggaagt gtgaaactaa gtaatagtct agttcgttga tagcaaatgg
    15841 atcgataacc attggctgaa cacgcaagtt tggttgcagc ttacgaacac ctgccatatt
    15901 tgccatttgg tgcccacgaa ccatatcttt cacttttttg gttgattttc cacggtttga
    15961 ccaaaggtcc atgacaacgt tagcaccagc tggtgtctta atccaagtac cacagttgcc
    16021 tagccaccac atggcaaagt tgccttcagg tacgacttct tcttcgattt cttcgttcaa
    16081 ccatgttccc cactctggga aagtggctaa aatccatgac tctcttgtaa tttctttgac
    16141 gtttggcata tgttgcctcc tttggatata attgttatct ttgagattag tataccaccc
    16201 ttcaaaacac taaaaaagac caagaaaaac acaggtttgt gttcatcatt ggactgtcct
    16261 tcaaatatct tccaaaaaag attaaactac tatttcttga tttataagtg tttgaacctc
    16321 ttcttggaac ttactagcca acttgctgtc tacaatataa gacgaaataa gactagaaag
    16381 attttcactg aaacttttgc tcttattacg aaatatattg tgtttaagat agtctagcat
    16441 tttcaaaata tcttctgctt caaggatagg attaaccctt aaaatcggaa atctgctatc
    16501 caaatcatca ttagtagtaa tcactacatc aacttgtgca atatcttcca cactcttaaa
    16561 ttgttctgtt gtaaatacag tgtcaatttg ctcatttgga aaataaagtt tgcattgttt
    16621 cagcaaaagt ctcgaaaccg caacaccttc atcacaaacg agataaactt ttttcatatt
    16681 tttttgagac gatggtgtat actttaaaaa tcctccaata tgaatcgtca aataggcaat
    16741 atcatcgtct gttagccgaa taaaccatgc tccttctaaa atttccgcag attttctagt
    16801 gactaaaaat aattctccat acttggatcg aatttgtttt gttagaggat ttttagaaaa
    16861 aataccgtaa gtctttctaa ataacaaggc tttacagtgg atcatcaaat ttcgtaacaa
    16921 atcatccttg ttctcaatct ccattcggat ttgtgattca aaataccaga taaattcttc
    16981 taaagcaagt tttaattgcc gaaaatcatc actttctgca tgaatatcca aatctttacg
    17041 ataggagagg aggagaacag ctacaagaga aacttcaagt cctgacaaag aaatttcaaa
    17101 cttttgaaac aaccgttctc ctaatttctt agacacctga tactctattc tttttcttat
    17161 caaagaaaat tctttctcta tatcctgatg tctttcttga tactgttcaa cattatgaca
    17221 gcttaacagc aaataaggta gaacctgcaa cataaaagtt atttcatgat gatttatttt
    17281 cttccctaaa tcttgttcaa ctaaaggaac ctgttcctta aaaaattggt tcatttcaac
    17341 agaaagcaaa cactcatcat ctaacctctc tttcatctta tcttctaaaa tagatacaaa
    17401 agtggcattt tcttccataa aaatatgata tagaagcgat tgaagatact gaattttatt
    17461 aagagggtgg gcatgaaggt ggtatccctg tgacttgctc acttgcaaga tcacctgata
    17521 ttgttccaaa gttagttgat aacgaatact attcaaatca ttgagaacag tattcctaga
    17581 tacctctgtt aactctatca atttttcaat cgtaatacgt tctttagaaa tacctatcca
    17641 tagtaacatt atcatcatac gttcatgcgc actcatgata taatcgtacg aatctacttc
    17701 cgataatagt ttacaacaag catctctctg ctcttccgtt aagtgaatac caattcgtgg
    17761 aatactaatg atgtgaagcg cctcgtcacc cagagcagca ttgattttgt caatgtgata
    17821 ataaattttc cttcttgact ctttcaaatc tttcgaaatc gccataatcg ttttggacgt
    17881 ttcttgatcc atcaaatatt gaagcaaatc acaacttgcc ttatccagta ccatattaaa
    17941 aaatccccca aatctattga tatcacagca attcttttta ttttaccata tatatatcaa
    18001 gcgctatttc taaaaaatct tttaaaatta cttcaactcc aactttactc tcaataaaaa
    18061 tcaaatgtaa aaagaggagc taaatttatc tttttctcct ccttcatcgt tcttactttt
    18121 gaccataata agcatttggt ccatgtttac gttggtagtg tttttctagt atgtactggg
    18181 gagcaggtcc aactcttgga ttgatttgtt ctgtaaagcg attcatcttt gatacttcct
    18241 ctagtacgac agagtgataa acagcattct ctggattttt gccccaggtg aatggaccgt
    18301 gattgcgtac aacaattcct ggtacttcaa ccgggttaag tccgcgatgt tcaaactctt
    18361 ctacgataac caggccagta tctttttcat aggccacttc tacttcgtcc ttggtcaaac
    18421 tacgggcgca agggattgaa ccgtagaaat aatctgcatg ggttgttccg tagaaaggaa
    18481 tatcacgacc tgcctgagcc caaccaacag cttctgtcga atgggtgtga accacactac
    18541 caatttctga ccaagcctta tataattgca catgagttgg gaggtcggaa gatggtctta
    18601 aatccccttc taggatctta ccatctagat cagtcactac catgttttca ggtgtcaatt
    18661 cgtcataatc cacgcctgat ggtttgataa caatgacacc gagttcgcga ttgacttcag
    18721 atacattccc ccaggtaaat ttgacaagtc catgttttgg caatgattga ttggcatcac
    18781 agactcgttt acgcatagca ttgattactt gattcatctt acatcaaacc tgctttctta
    18841 atgagtggat agagaaaagc ttgcgcctct tgaatggctg cgcgtgtttc ttctactgtt
    18901 tcacaatttt cagaccacat ttcgattagg aaaggtccat tataattggt ttcctttaaa
    18961 atatcgaaag cttcttccca tttgacacaa ccttgcccga aaggtacatc tcggaactgg
    19021 ccctttgaac tttctgtcac tgcataagta tccttgagat ggagagctgc gatggcatga
    19081 tgaccaagat aaaactcact atagatatca ttatgccatg cagacacatt accaatatct
    19141 ggatatacaa agaggaaggg agagtcaatc tctttttcta tagccaaata tttttcgatg
    19201 ctattgatga aaggatcatc cataatttca atagcaagta ccacctgagc ttcttcagcc
    19261 cagtcacagg cttttctcaa atttttgata aaacgttggc gtgtctgggg tgccttttcc
    19321 tcatagtaaa catcgtaacc agctaattga atcgtacgaa ctcccaagtc ttgagctaat
    19381 tcgatacatt ttttcataag ttctagagat ttttcctcta gaactggatc ttttgatccc
    19441 aatgggtagc gacgatggcc tgaaaaacag atagaaggaa tacgaacacc agtttcatag
    19501 attgctttga caacttccaa gcgttcttcc ttactccagt caagtcttgc taaacgctcg
    19561 tcacgttcgt caatagacat ctcgacaaaa tcaaagccta actccttggc aaaatttaaa
    19621 cgttctagcc aagtaaagtg tgttgggatt gccttttcat aaattccaat tggacgtacc
    19681 atgatttacc cccaaattcg tttgatttca tccttgaagg cacgcgctgc tcctgctgga
    19741 tccacagcct ctgtaattcc acgacctgcg ataaaggtaa agacatcaac accttcaaag
    19801 agtttgagag tatctacatc tagaccacct gttacagata cacggaagcc catgtcaatg
    19861 agttttttaa tcttattaag gtctttttca ccccaagttt caccagcaag aagagcatca
    19921 cgagattggt gataaatagc ttgtgagata cctgcatcta gccaaagctg agcttgttca
    19981 aaagtccaat cgccataaag ctcgatctgg atttcgcctc gttctcctcg ttcagtcttg
    20041 atagccttta gagctgcttc catagtaggg atggttgcac aacagataca agtcatccag
    20101 tctgctccac gaaccgcatt atttttagca actgttccac cagcatcagc acattttgtg
    20161 tctgccacaa taatcttatc tgggaaaagg ctacgcaaga cttcagccag ttcacttcca
    20221 acttgaagca agcaaacagt tccagcttcg ataatatcta cttcctgacc aacagaaaca
    20281 gctgctttaa tcgctccttg caagtctgaa tagtctaatg caacttgtaa attaggtatt
    20341 ctttttgtca tttctttatt cctctttcta actttccaaa tccaatcctt cgagataagg
    20401 gctatcctta gattcttcaa tcatagccaa gacatcttct ttagtctggc aagcctgtaa
    20461 acgtgcaata gaatcttcta attcaaacag ggcaataatt tgtggaatgg ctacacttgt
    20521 gtgaattttt gagcttgttg ctgctagtgc caacaaaaca gatacctctt tcccatctga
    20581 aaatacaaca ggattttgta aggtaatcaa tgaaaaggca tcactttgca caccagcttc
    20641 aggtctagcg tggggcatag ccatacctgg catcaagata tagtaaggcc catactcttc
    20701 agtcgattca atgatagcat cgtaatactc tggcaaaatt gccccacttt caattaaggg
    20761 atctactgct accttgactg cttctttcca attgttagcc tctaaaccta gtcggatcga
    20821 gtcattgtca attaaagctt gttttaaatt catatctgcc tcctttattt aagagggaga
    20881 aggacagaaa cgataactct cagtttctgt ccagccccct ccaacctttt actgtagtgc
    20941 ttgactgagt ttttcggtga tttctttatc atccatcaag ttatcaagcc caattaactt
    21001 cccattagtt cgcccttcca attcttgaat caaatgaaga gaagcgatta cgatgtcata
    21061 tcctactgct aaacctttag cttcaccgac actgcatgaa ttgactgtaa aatctgtttg
    21121 attaagctta cggagagcat tttcaacctt catcttgata accattgatg aacccattcc
    21181 atttccgcac gctgctaata ctttaaccat tttatttctc cttttctaga tactaagctt
    21241 cttcttgaac ttcaccgttg taatatttct ctttatcttt tgctttggca aattgaagtt
    21301 gaggaataac aagcaagaag agacacacaa gtacataacc aacaatacca aggtatttga
    21361 agatatatcc aaatccaagc catgggaatt caaagtcgat atttccatgg tagccaccat
    21421 aagatgccaa atcgagaagg gccacacaaa gagctcctag agcaacttga aggacacctg
    21481 atataaagga aaggataaca gccgctttcc atccgccgcg tttatcagcg tagactgcaa
    21541 tggctgcatt gtcaaagaac actggtacaa atcctgtaat aataagaatc ggatttttaa
    21601 agacgatgag caaaacaatt gtaatcaatt gaccaatcaa accaaaggta aatcctgaca
    21661 agacagcatt tggagaacca aatccataag aagctgcaac gtcaaccgct gggaatgaac
    21721 ctggcaacaa tttgtttgaa ataccttgga aggcgtttgt caactcagat acgaacattc
    21781 ggacaccttg catcaaaacg aacaagtaaa ctgagaaggt aaaggctgtt tggataatgt
    21841 acataaagaa atcttgttta gcaggattga atagagttcc tgaagtgatg acttctttat
    21901 tagacataat gtctggaccc aagattaaaa gaatggctcc gaagaatacg agcatcaagg
    21961 tagcagatgc aacaactgta tcgtggaaga ttgagaggaa cttaggtaat ttaagattgt
    22021 ctaaactttc ttctttctta ccaaagcgtc ctgctacttt atctacaaac cagattgcaa
    22081 attgctgttg gtgaccaatc gcaaatccgc caccaccagt caagcgttga gttgcctcaa
    22141 cagtcatatt tgaactaact gcccagtaaa gtccacagat gataccaatc gctgctgtac
    22201 cgtaagcatt gcgcaattgt ggtactaaga atagaaccat aagagatact gttgcagctt
    22261 gttgtaccat gatgtgacca gtaataaaga gggttcttac cttcgtaatc tttcgaagag
    22321 ctacgagcaa gatatttatt ccaaaaccaa tcaatagagc tgtagttgca gttccaacaa
    22381 aatctggaaa ctctgctgca attttgttgt ttgctgcagc aagtccaaag taagggtcga
    22441 taaccgctgc accaatttgg aatttgtagt taagagctgc taagattgga cgaaaggttg
    22501 taaccaaacc accagcaccc acgttaagca acatataccc tactgttgat ttaacaaacc
    22561 ctgaaaaaac gtcatgggca ggttttttca aaagtgcata tcctatcaac accaataaac
    22621 ctacgaaaaa tgcgggattc tgcaaaatat tgctagaaaa ccaatttaga acacttgaaa
    22681 cgacttccat aattgttctc cttttgaatt gtttttgtaa gtttattata taatgcgaaa
    22741 gcgcaaacaa aaagaccaag aattacacag cggactgttc actcttggac tgtatgattt
    22801 atgatgtttt acaaattatc ttattttctc gtagctagat aatagggaag aattttagaa
    22861 taagacttca ataagccttc tacgatttct tcttcagacg aattttctgt cataggaaca
    22921 tctaccttca ctaaaacttt tcgaacttct tgactcctca ccttctcgcg taaagtacga
    22981 cgcttttctt cattcgcctc ccaccgttga ctttgaccat tagagtaggt tagataataa
    23041 atccctttaa cggttggaat gtctaaaact ttggtctgct tgcccagtgt ttgctcatcc
    23101 ttcttacgtt cgatgaaact gacttccaaa gaaattccaa agtcagtaga tgtcccatac
    23161 aaacgtaagg ccatcatagg ttctgtcact tgtccgtctc tctgtagata aacccaaaaa
    23221 tgtggtctca aacgctgggc ctgattcatc cactgactag tctgttggag ttgccattct
    23281 ggatggcttg cttgaaaggc tttggccagt tctgtaaaag cctttcgggc ctcttgtcct
    23341 ttgtggcgga acgccagcat cttctctcgc tctgctcccg ctttatcagg actacggtac
    23401 tgcaaaccag aaaagtctag atagtctctt atcttattca acatcagttt aacctcctct
    23461 aactagcaaa aaatcaggtc aaccctgatt ttacttattc tgtatctaca acaacatagc
    23521 gatttggctc atcaccttca gagtaactag tcacgccatc catacgtgaa ataatacgat
    23581 ggataatctt gcgttcgcta tttgacattg gatctgtttt atgactgcga ccttcttcca
    23641 aaacacgatt cgccaatttt tgcgcatagg tctgcaagac ttctgcacgg tgttcgacat
    23701 aatcattgac attgattgta acgtagaagg ttttggaata gcggttgtaa agataatttt
    23761 gagccaacag ttgcaaggcc ttcaagactt taccatggta gccgataata cgacctggtt
    23821 cgttggtgtc aatttgtaga ttgatgctac gacggttata atcatttgaa agtgtagctt
    23881 caacatccat gtcatccaca atcgcttgaa cataggcagt cacatccgta gccacctggg
    23941 caatatcata actttgctcg accttcaagc ccatctcttt caagtcttga ttttcagttt
    24001 gatcttgctc agtttcaagg tcatcagcgc ctgcttcttc cctcatcgct tcctcgattt
    24061 gaagttcatt taaaatctca atgtgaccag tttcttctaa gatagtgctg gcatgtcttt
    24121 catgttttaa gatttcagcc ttgacttcat cagaaatacc ttgaccttct tcctctattt
    24181 ttttaatagc attaaccaca tgaccaaggt caacggtttc ttcactaacc gtcttcacag
    24241 gctcgttcaa atcattgatt tttttcggaa cgccttttac tacctgttga tttgctttga
    24301 caacagtcgt ttcactaatc gcttcaatat ccacttgggc tggtttttta ccaaatagac
    24361 caagaaagcc ttttttctcc ctagaaatga ctttgatatg agccttcatt cttggaatat
    24421 ctaattcttt caatcctttc tggattgctt cttcaacagt tgaacctgta aatactacca
    24481 ttaccagatt cctccttatt tatttcgttt tctgagcctt tttcttggct tttctttttc
    24541 tattttccaa atctttttgt gtctgtacta cggcctcgcg ctctgcgata atcttgaatg
    24601 gattattcaa gaaataggtt tgcaagactt gataagcatt agacactgtc cagtataggg
    24661 cgactccacc tggcgcataa actgcaaaga taaaaatcaa gactggaatc ccatacatca
    24721 tcgcagtcgt agcgccattt cgctcagaca aagctttgtt ggacaaccaa gtacttaaaa
    24781 aggtgaatac tgctgctaaa atcggaagaa caagggttgt atccacacta ccaaggttaa
    24841 tccataagaa atgacctgtc tttaaaaagt caactcttga tagggcttgg aacagggcca
    24901 aaataaccgg catctgaatc aaaatcggcc aaagagagtc tgactgtctg acacccattt
    24961 ctttaaatac tttacgcatt tcctgctcta gtttggttct gctttccata tctcgacctg
    25021 gatattgttc tcgaagcgcc ttaatgcgtg gctgagcttc ctgcattttc ctagaagcca
    25081 ccatttgcac ctgaaagact ggcaagagga ctgtacgaat caagaccgta aagagaataa
    25141 tccccactcc gatactaata tcaaacgata aaaagcgaat gatttccgca aagaagtaaa
    25201 ccaatttact ccaaaaatca gccgattcgg ctgtaatatc gctagttacc ccattagtcg
    25261 cacaggctgt catgattaac agagacagtc ctagcaaact agtcaacttt agtttctttt
    25321 tcactcccat ttccttcccg gtaaatcttt gataatttta atacatggag tagatttttc
    25381 tccatctctg cgtatcccaa ggtttcgact ccttttcgag caatgacaac aaagtcgaca
    25441 tcttctacca gacccccttt tgcattctgg ataatatgcc gaatccgtcg cttaatttga
    25501 tttctagtga cggcattccc cagttttttg ctaactgata gacctactcg aaaatggttt
    25561 ttctggtttt ctaattggta gaccacaaat ttgcgattag caaaacttgt cccctccttg
    25621 aaaatcgcct taaaatcttt ctctcttttt acacgaaagt ttttcttcaa aactcaactc
    25681 catctattaa attactacta ttataccata tttttcaaaa aagccaatca tagcaaggtt
    25741 ttggacaatt tcatcagaaa aagaagctgg aaaaataact ttcccaactc cttgtattga
    25801 atattttttt agtttcactt attttttcaa gcgttcaacg tcacgggcaa tgactaattc
    25861 ttcatctgtt ggaataacca agacacggat tttagctacc tctgttgaga tgtctcctgt
    25921 aacgccaaag acattctttt catcatcaac atcacaacca aaccacgaaa tccctgagat
    25981 tacatcacga cggaaattct ctgcattttc accgacacct gctgtgaaaa caatggcatc
    26041 tgctccattt agcactgcaa ggtactgacc gatatgtttt tggatacggt caacatacat
    26101 ttcataagcc aagctagcct cgtgattccc ttctgctaca gctgcttcta tatcgcgcat
    26161 atcgctagaa ttagcagaaa ctcccaaaag acctgattca cggttaagaa cacgactgat
    26221 atcttctggt gtgttaaaat cctctgtata ttgcattaaa taaggaatga tagctggatc
    26281 aatatcccct gtacgcgttc ccatcataat accaccaaga ggagtgaacc ccatagaagt
    26341 gtctacagat ttgccggctt tcacagctgt aattgagcct ccgttaccaa tatgacaggt
    26401 aattaacttc aagtcttcta atggacgtcc caagagtttt gcagcttctc ctgctacaaa
    26461 ctggtgactt gtaccatgag caccgtattt acgaaccttg ttttctgtgt aatattttgt
    26521 tggtagaggg tagcgataag ctttctttgg catacttgtg tggaaggaag tatcaaaaac
    26581 aactacactg gtaatgtctg gcaacaattc cttgaaggca cgaacacctg ctgcattggc
    26641 cgggttgtgt agaggagcca acaaactcaa ctcttcaact ttttctaaaa catctccctc
    26701 aacaactgtt gattctttga aatattctcc accagcaaca acacgatgtc caacacctgt
    26761 aatctcgtca taagccttga taatatcgaa acgaatcaag tcatccaata aaattttaac
    26821 ggcttgtgta tgattttcaa tatccaaaat ttgttgttca gaacggccgt caaattttac
    26881 agttgaaatt gaatctttca aaccgatacg ttcaatcaaa cctttcgcca atactttttc
    26941 ttctggcatt aagtataatt gccatttcaa acttgaactt cctgcattga ttgcaattgt
    27001 ttttgtcata acatgatacc cctttttaag cgttttcaac tattataaca aaatctattt
    27061 tatatttcag taccttgagt ccatttttga aaattttctt taaatttcat taaaacactt
    27121 gcatcttgca agctagcaag tggataaaca aaaggctcca ctgctatttc acttttcttc
    27181 tgtaggataa aaatagtctt agattgttta gcattagcaa agagattttc aggtaaacta
    27241 atcatagcaa ccagacttgc ctcctctttc aaccagactt tcaacaaatc actttgagga
    27301 ctggtcaaca aatcactcgg agctagaaaa atagcatatc catctgactt aaggtactta
    27361 aacccttgtt ccatgagcaa gtgatgagcg taagtatgtt cttggctaga agcaacttga
    27421 tggcgcgacg caacggcatc atcaggataa tagccaacag gcaagtcact gatgaccaca
    27481 tcgctttctt tgagcatttg tgggcgaacg gcatctcctt ggacaaagcc agcctgcaaa
    27541 ccaattacat ctgccatgct agctgccaga tcaatcagca aatcatccac ttccattccc
    27601 aagtaatcca cctttttatc aagcgaggtc aagaaagtag cgcctagaat tcccatccca
    27661 gaacccattt cgaggatagt aatttcctcc tctgtaaaca actcttccac aataaatacc
    27721 aaaagtaagg caatagcatc tggcgtaaac tggtgattgg cctgcaaggg ttctgtttgc
    27781 ccagccttca tcaagagaaa ctggtaggtc ttgagccatt cttctttgcg tagtgctaaa
    27841 cgcttaaggg cctgattgtt gtctttgacc tggtttagct cagtttcacc atccagatag
    27901 atgctatttt gctccaccaa ggcgtcataa aagttggtcg ccaaatcact ttggatgact
    27961 tggacattct ctagtaaata gatataagct tgttcaattt tttcaaaatc catattccta
    28021 tcttatcaaa tttcccttct tttttccatc cttatagaaa aatcactccc tgactaggcg
    28081 agtgattttt gggatactgt taaaaagaat tctgagtgat tcccttgaaa caggtcttca
    28141 gcgctataga gaatctgact atgcacagat gaaaaaccat gctcaattag cttgttttcc
    28201 agttcagcta aatcaaatcc atgatgatta gcttctgtct tggtaaaatc agcaatgatg
    28261 agtttcccat cttccttcaa atgttgatga aacagtgaga gatccgcatc caaatcaggc
    28321 atatgatgaa gaacccgact aacagcaagg caatcaaact ctttctccaa gggatttttc
    28381 ggtaaatctt gctccaaaaa ctggatattc ttgattgctt gctgctccgc tttcaaacga
    28441 gcttactcca acattttctc agaaatgtct acaagagtaa ctgacttagc ctgcttggct
    28501 aggggcaagg ctaatagacc cgtgccacca ccgaaatcta aaattacttt gtctgataaa
    28561 atatcaatct gtttctcgac tgcttgacat accaagtttg cgaggaagat atttttaggg
    28621 gagtcgaaag tttctgcttt gtggttaaaa tcatgtttca tatctttagt ttagcacaaa
    28681 gtatagtaaa ctgaaataag atataaacaa atgaattgga gcttaacatc catttccagc
    28741 aattttctag aaactacagt ggactattct ggattcaacg cattatagtt gaattgacta
    28801 ggaattctct ttcttttcag gcttctcttc tgattttttc ttctccactt tttcgcttga
    28861 atcggtcgct acctcttcct ttttatctct tttctcttct ttgattttga ctgaaggaaa
    28921 cagaaactca tattggctct tagacgtacg aacagtcgtc accaagcttg ttttcttgtt
    28981 ttgatagctt acctgaccta gattaaagac ctgttcccca ctttcttgct cggctttatc
    29041 cttggttcgt ttagccatgg caaaagcaac caatttttct ttatttaaag catagtcttg
    29101 atagtgggcg atttgtcggt tcaaataaaa ttgcaacaaa agactaaaga tggctgctat
    29161 ggtgactgcg tagaggagaa cacctgcctt aactttcttc tttttccaca cgatagatga
    29221 actccctttc taagcctttt tgaaactgga aacgaaaatg aaccagttga ttgtcctctg
    29281 taatctgagc tgatttgagg ccataaacca taggctgata cccccgtcca ctagcatcgg
    29341 ttttacgaaa atcgtctgac tttgacttac cgatggcgat gtccttgcca tcttgcttca
    29401 tgtataggcg attgctttct actttttcga actgcgaacg gtctaattct gcctcaagtt
    29461 ggtccacaaa caagagccac tccttttgct cgctttgttg ctggtagcga acttctgaaa
    29521 tgaggagctg actcatagct tgaaaaagga gtaatccccc actgatgaca atgagggcaa
    29581 gcagggattc taacaaggta aaagccttga ccttatggct ctttgattgc caacaactgt
    29641 tctgaaccat ggtagacctc caatcccttt tcactagaaa atacctgaat ctcaactccg
    29701 ttgatgctta cctgattttg ccccgtctgc aaggccatct tagctaccct caagacttct
    29761 tccttttgca agatttttgc ttcctcttgc ctattttttt gaatttgtcc caaaaggagg
    29821 gtcgcaatgc tggcaaagat agctagagcg actactgctt ccagtaaaat cactgcccta
    29881 attttttgtt tccttaatgc gtttaatttt tccatttcct agatataatt gatagcgaat
    29941 cgctccttta ctggtctgaa attcaacctt agccagggac gaattgcccc cagctcggtc
    30001 aaatgtaata ctttggcctg atggtgcctg aattccttta ggaactgtca acttttgacc
    30061 gccattgcta atcatctgcc catccaagtt cagactagtc ttttgttgac tagctacact
    30121 gcgtttttgg gtttcccgat agagttcttc aaactccata aagaaaatct gttcctctac
    30181 cgctgcaaaa gtggactgga cagagccgga caagcccaag gcaaggatac tcacaagtcc
    30241 caaaactaag agactttcca gcatggtaaa ggccttaatc atagacttta cgatttgctc
    30301 ctacattttt atcattgtat tctttataag ctttagcctg ttcttccgtg atgcgtccat
    30361 cttcttttaa cttgcttagg ctagcatctt cattcttttc caagctataa agttctgcct
    30421 ggctttccac caccttaaca acagctgctt ttcctttgtc attgactgct tctttttgct
    30481 tggtcagatt aggtacaaag agcaagaaaa gcacgctgat aatcagcaag accaccaaca
    30541 tttccaccaa tgtaaaagct ttaaccttag cttttttcaa gaatgtcatc atttttttca
    30601 ttttaaaaat ttacctccat attttgatac atgggcatga gcattgccgc ataaagtaaa
    30661 acgataatca gtgccacaaa gataaaaacc agtggctgca ccaaattcat ggtgcggttg
    30721 actcgggtaa aaaaggcttc ccaagttttt tcagcataga tttccaactc actacccagc
    30781 ttggacttaa cttccccata ctctatgata agactcaatt ccttcctaaa gaaaggatag
    30841 gttcctatcg tctgagaaaa ttcacggcca tttttcaggg tttgagccag atcttgaccg
    30901 atttctttaa agagctggga accttgttcc tgcatcattt gaaaaatctg cgtcagctcc
    30961 attccctgtg aaatcatatt cccccattca cgtgcataat aggctgtcaa gtaggtctgc
    31021 acaaagattc caataaaggg aaggcgtgct aagatagaaa agacactcat cttagaactt
    31081 cttttataaa aagttagtgc taaaagggca agcacggaaa caagccctac catgcctaga
    31141 aaaatttggg gcagattacc gataatttgg gtggcaatat tgctactatc cagttgtggg
    31201 agcaggtaat tccgtagccc cagcataatt aagagaagaa aacccagcaa aatcaaagga
    31261 taggtcgcta cttcaattaa ctttttcttg accttggcca gattgtctag atattcttct
    31321 atctttccca aactcaggtg gagattgcca tgaacttcag ctagggataa ctgagtgaca
    31381 atagcacttg aacatcccaa actttccatc atttctgaga atgattcccc ctgagacaag
    31441 cccacacgca tctgggtcac acactgcttg tccaacaaag cactcctatc taaaaaggag
    31501 atggtctcca ccagatgaaa accgctagaa aagagattgt taaatagggt gatgatattt
    31561 ttttgcttag ctgtagctaa ttttttccgt ctcagcctga agacttgtga tatgtccatc
    31621 tttaagaagc tggtcaattt gctcattcca cttgactgct tggtgttctt gataatctct
    31681 gtttgcaaag tcaacgattc ctcctccccc gattaatctc tggtagcaga ctccttgcaa
    31741 aacaactgcc aattcttctt cactcacacc caactccagc agacgctcat aaacacctcg
    31801 gatactcttg gcatgaatgg ttgaaaagac tgtcgcacct gtcaaactag ctctgaccac
    31861 tgcacgcgcc gtctcgctgt cacgaatttc tccgataatc aagagatctg gtcgatgacg
    31921 caaggaaagt ttgattagat tttcataggt taggccgatt gcttcgttca actgcaactg
    31981 aagcatgtcg tcctgcttga tttcgacagg atcttcgatg gacataactt gctgcccttt
    32041 aaagagtgac ttggacaatt catgcatcaa ggtcgtctta ccactcccaa ccggaccagc
    32101 aaaaagatag agtccccgtt gcctgtactg cttgcctaat tcttcaatat cctgaaacca
    32161 aaaatgcagg tcctgctcct catcgtgcaa caaacggata accaaactct catgcccccg
    32221 ataatcgcct acagtagata aacgtagaga cgctatcttc tggtcatagg cataatcaca
    32281 ggaacccagt tgactacgtc ttttttctcc cacattcata cccgccacaa acttaaagtg
    32341 actgataacg gctgcaaact tttcaaaatc atagctacca attttacagc gctcgtctcc
    32401 taccctcata tgaagctcat aggcgtctaa cttagggaca aaatagatat cctgcgtccc
    32461 ttttttccga gctgaacgaa tgatttcttg tgcaatttct tgaaccatac ttacctcctc
    32521 acctatacta ttcgcaaaga gttagaaaaa taaaaaaagc aactccaaaa aagttacttt
    32581 tctctatttt aatttcatac ggcaagaacg attcctttcc tgactagttt gtttttcata
    32641 gcctgagcgt agtttttcgt ctgggataac ctgctcatcc tgcaaaagag ccaaagaatg
    32701 gtattgttgt aaatactcat cacattcatc acaccagcgt tggtcttccg ggtcccaaaa
    32761 aatggtcatc aagtcgcttc tacttttata aagaggggat tcttgttcca atctaaacca
    32821 gcaagttttg tagtatttga gagcatcata atactggtca aattttctac ttgctacaat
    32881 atcttcttcc caaccttcta agaaccacca cggttcaaaa tctccgtaca tttctataac
    32941 acgatacata ttcattcatt cctttgtacc gtatattata accaattccg ccagacaagg
    33001 aaagaaatat gctcatttct taattttttg ataaaaaatc cagccatctg atggatgact
    33061 gaatttctat ttacttatgt acaaaaatat ttttactact tagacttctg agatatcgtt
    33121 ttcgataatg accttaatgg catggtggtc tgctgcctta ctgaagactt cgtaggcttt
    33181 ttcaatttca ctgagtttga aatagtgagt taccaatttt tctggttcaa tcttatgact
    33241 ttcaagtgct ttcaacaatt gtggagtcgt atttgtagat accaaaccag ttgttacatt
    33301 gatgttgcga atccaaagtt tatctaaatc gaattcaact ggtttaccat gcacaccaca
    33361 gttggcaacc gttccgtcta caccgataat cttttgacag aaatcaaatg ttgcaggaat
    33421 accaacagct tcgatagcga catcaacacc acgaccatct gtcaaatcat aaatttcttt
    33481 aatggctttt tcagggtctg aagaattaac cttatgagtc gcaccgaatg atagggcagt
    33541 ttccaagcgg ttatcgtcta ggtctaccat aatcaattta gctggtgaat agaattgggc
    33601 tgttaaaaga gcagccaatc caactggacc tgaaccaata atggctacgc tgcaaccagg
    33661 ttctactttc ccttttaaga caccaatttc atatccagta ggcagaatgt ctgacagcat
    33721 aaccaaagct tcgtctgaca agtcttctgg agtatggtaa agagtattat ctgcatgagg
    33781 gacacgtaga tattcagcct gcataccatc aatcaagtga ccgaaaatcc agccccttcg
    33841 tcttcacagt gggcataaat tcctttttta cagtagtagc atttaccaca ggcacagacg
    33901 caagaaatca agaccttgtc accttttttg aagttggaaa ctccttcccc aacttcttca
    33961 acaatcccaa tcccttcgtg gccaagaatg gtaccacttt ggcaagtagg aacatcccct
    34021 ttgataatat ggaggtctgt tccacaaaga gtggttttta caatacgcac aatagcgtct
    34081 gttggcttgc gaataactgg tttgtctaca tcaacaaaag aagcaagtcc tggtttaaca
    34141 taagtatagg cttttataaa gcactcctcc gtttttttat ttgtactatt tatagttcaa
    34201 ttgtaagcct ttttctttgt ttcttcaagc tttttttgtg atttttttaa ctttttattt
    34261 accagtaaag taccctatat aaaaaagcag aagctagtct ctaacttctg ctttctctct
    34321 tatgcttgat aacgttttac gccatctagg taggttgcta ccaattccaa atctttatct
    34381 aatacgatga agtcagcgtc gtagccttca cggatttggc cacagacgtc atcgatgtga
    34441 acggatttag ctgggttgaa gctggccatc atgactgctt catgcggatt cgcaattccc
    34501 cattcgacca cattcttcaa accatctttg agtttgagga tagaacctgc caagttacct
    34561 gtcgatttga ggcgtgcagt tccatttgca acgacaactg ggaattctcc caacatataa
    34621 tctccgtctt ccaatccccc agctgtcata cagtctgtga taagagcgat gttttctgtt
    34681 cctttttgtt tgataagaat ttcgcaagcc tttggatcta cgtggtgacc atcacagatc
    34741 aactctgcat aggtatgtgg caattggtac atggctccaa ccatacccaa ttcacggtga
    34801 gtcaacccac gcattccatt gtaggcatgc acccaaacac tcgctccagc atcgactgct
    34861 tttttggctt catcaaaagt cgcatttgaa tgtccaagag caaccgtcac accttcgccc
    34921 gtaactgtac gaacaaagtc ttccacccca tcacgttctg gtgcaagggc aattttatta
    34981 agcaagccat ttgccgcttt ttgccaagaa tgaaactcct caacacccgg gtctctcata
    35041 taagttggat tttgtgcccc cttaaaagtt tctgtaaaat atggaccttc ataataaatc
    35101 ccacgaatct tagcacctgt tgcttcttta taatggtttc caagattttc agtgactgca
    35161 agcaattgct cataagtggc tgttaaagtt gtgggtaaga aactggtaac accggtacta
    35221 agaagtcctt cactcatagt atgcaatgta ccttcaatgt tgttgtccat cacatctaca
    35281 cctgcatatc catgaatatg agtatccaca agacctgggg caatgctata acctgtatag
    35341 tcaatcacct cagccccttc aggaatctgc tctgcatgtt ttccaaactt gccgtccaca
    35401 agttccaagt aaccacctcg acgaactccg tgtgggtaga aaaactgatc cgctttaata
    35461 tagttaggca taatgttaac ctccttaaaa gattgattct acaatttatt atgtcaatta
    35521 cattataaac ctttcttttt tatttgtaaa tggtatagac ctattttttg gagatatttt
    35581 aaaagagctg gatttctcca actcttctct tttttaatac aagttatttt gatttaaccg
    35641 gcttgtcttg agctgtctgc aaagctgtgg caatcgtatc tgcatacaat tttgctcctg
    35701 cttcgatagt gctactctca ctcccgaaat gaacctggtc tgttccagcc caaatttctg
    35761 gatgctcttt cgcaacttga ttccaatctg ctatcgtaat gtaaggtgtc ttctctgcca
    35821 attctctcat ataggcagca gccttctcaa cgatggcata ggtctctttt gtcttatctc
    35881 cctcataagg agtcaccaaa atcatatggt gtcccttagg aagatttttc acgatactgt
    35941 cccagtcatc cttgtaattc tcaggattat ttaccccagt cgcaatgacc accgtcttag
    36001 gtaaaaattt attctggcta ttatttagca tgatttcatt tgcggtcttg gttgttacgc
    36061 tgacctgcgc gttaatctgt gctccaggaa gagctgtctg tagtgctgta tttgccctta
    36121 aagccactga gtcaccaatt aacatagtgc catcagcaat tcccaaactg tttgcatctg
    36181 cccgttctgc catcaccttg gtctggccaa tatttgttgc agcttgcttc aagccattga
    36241 cagtcaagtc tgtctcaaac gctcccactt gtggtgccaa caaggtcacc gtacagacaa
    36301 tgatggtcaa aattcctgta cttgctacaa ggattgtatg ggtataaggc aggggacgaa
    36361 gggtttggac aataggtgtg ttctttcctg caatccaagg ttccaataca tagaatgaca
    36421 gactggcaaa gccataagaa caaatcagag tcagtaatac agcaagaaga tttgatgtca
    36481 actgtgagaa aatgatatag aaaggccaat ggaaaagata aaccgcatag ctagtatccg
    36541 ctaaaaagct gataatcttc ggctcctgta tatgatgtgt cttttcatgt aagacacgcg
    36601 ccgccagaat catggcaaga gctacaagac tggcaagcaa gaagccgata agataggcaa
    36661 aaagataagt gaatttgaca aagaaagtca aaagaactag gaaaccaaag cctcctccaa
    36721 aaactaccaa agtctttcgt aaatcccaga ttttatccaa ctgcttgacg agggaagtcg
    36781 tctgacgaac gcctacaata gttgctaaca tacttcccaa aaagaatgga tagacatgag
    36841 ttaaactgga gaaataaaca gaagaataag aggtcactag aaaactacca ataaacatgg
    36901 agaggaaact gatcaagaag gcagcagcag ataagagaaa gaccatcccc ttcaactgac
    36961 catttgattt agcttgtttg gataagaacc aaactgccaa tccccaaaga atatagtagt
    37021 gaacctcaac tgccaaactc caattatgaa caaacaaatg aggaatgaac tgagattcat
    37081 aactcccacc tgttaggagt tcatagaagt tggtcataaa acctaagacg cccgcaatct
    37141 ggccaccaat tccagcaaca tagtcttggc gaaccaagaa agtaaaaggc atggtcacca
    37201 agaccatcaa aaccacaggt ggcacaatcc gataaaagcg tcttctaaaa aatcctatca
    37261 aatcaatctc atggttttta gaaaattctt caatgagtag agctgtaatc aggaaacctg
    37321 aaaatgtgaa aaagacatct accccgaaaa atcctccagg aaagatcgtc tgaaagaagt
    37381 gatacaagag taccaaaagt aaacctgtaa tcctaaccaa ggaaaaccat ttaatgcgca
    37441 tacgagttta ttcttccttt cattgtacac tttattctat caaaaaaaga agaaaaatcc
    37501 taagagaaaa cttaggattt ttagcttata tcaattccat tttagaaatt acgtcctgac
    37561 ttattatagc catatttttc cacaaaatac tcacggaatt ccaagagatt gtcatccatg
    37621 atggcttgtc gcacttgctt catcaagtta agcaagaagt aaagattgtg gtagctagtc
    37681 aagcggatac caaaggtttc atcagccttg agcaggtgac gaaggtaagc gcgtgtatag
    37741 ttattacatg tgtagcaatc acactcagga tccagtggcg taaagtcctc agcaaactgg
    37801 gcatttttca caaccaaacg tccttgactg gtcatacaag tcccgttacg agcaattcga
    37861 gtcggtaaga cacagtcaaa catatccacc ccacgaatga ccccatcgat caagctatct
    37921 ggcgctccca cccccatcag ataacgaggt ttattttcag gcagcagttg agttgtaaag
    37981 tccaagaccg cattcatctc ttcatgggtt tctcccactg ccaaaccacc gatagagtag
    38041 cctgagaaat ccatgctgac aagatcatga gctgattggc ggcgaaggtc ttcaaatcct
    38101 gcaccttgca caattccaaa caaaccttgg tcatgtggac gacggtgagc cttcaaacca
    38161 cgctcagccc aacggctggt acgctcgatc gatttcttaa cgtagtcata aggttgataa
    38221 aactgaggac attcatcaaa ggacatcatg atgtctgaac ccagattatt ctgaatagag
    38281 atggcttttt ctggggatag gaacatctta gaaccattta gatgattttt aaaggttact
    38341 ccttcttctg tgatattacg gctatctgct aaagaataaa cctgaaaacc accactatct
    38401 gtcaagatag gctggtccca attcatgaac ttgtggagac caccagcgcg tgcaatgagt
    38461 tcatctccag ggcgaagcca gagatgatag gtgtttgata ggataattcc cgaacccatc
    38521 tccttcaatt cttcaggtga ctgagttttg acagtggctt gtgtcccaac tggcataaac
    38581 ataggtgtcg gaaaggtacc gtggggagtg atgatttctc ctagacgagc tcctgtgtgt
    38641 ttttctttct taatcaaacg atatttgatt ggtgaatctg acatttttta cctccgaagc
    38701 tgggaaagac agtcccagtt catacagtgt gcccaaggac acactgtatg attttatcaa
    38761 aaaaagtagg aactgtcacg aactatgtag aagaactatg gtataataag agaatgaact
    38821 atccaaaaat tgatttaaaa acaattcgtc aggagtcaaa acattttcag gctgacaccc
    38881 cccgtctctt tctcctctat atccttccca gtatgctggt catcttatct agttttctta
    38941 atcccttatc tcggatccac gggactgttt tagaacagcc atttttcagc atacttggcc
    39001 aaatacttca agcctacctc tttcctctac tagtctcctt tatcgggact attcttttga
    39061 ccagttccgt ctatgcaaca ctgacactca tgaaagattc taaaacggag ccatctgtaa
    39121 aaaacagcct agctctcttt gatgaggagc gcttttctca aacctttttg accctacttc
    39181 tcaaacgttt ctatctcttt ttatggagta tccctaattt acttgggatt tacctcctct
    39241 tttatagtag ctttttagcc aaaaaattcg tcaccctaca tcctgagttt ccaaatttag
    39301 ctctctcatc agttgaaacc gagcgtttcc tcatggtctt tggactctac tttcttgcaa
    39361 gtctcatctt gatcattgta ggaaatatcc tctatattcc acagtattat gcctattcac
    39421 aggtggaatt tcttctttgt tatagtctag acctaggaca ggtcccacca agacgaatcc
    39481 taaaaactag ccgttccttt atgaagggct acaagttcca gcactttgtc ctagatttac
    39541 agcttcttcc ttggtacttc ctcaattgga ttacctttgg cattgctagt ttttcactcc
    39601 taccttatat ccaatgcaat aaaattatgt tttaccgagc agtattggct cgaaaacgtc
    39661 caaaagcttg aaggtttttc ccctcaagct tttttctatc aatgagtttc tccgcctacc
    39721 aacttgaggt cctgatctcc atgttctatc atagcgccga ttgctgcttc tatccctcgc
    39781 cgaatatcca ctaaactcat agctggagta gtcggtctgt tcaccacctg ttccatcata
    39841 taaggaatat gcataaaacc tgccttaaaa tatggaaatt tcttttctac caaatagagt
    39901 gcctgataca tcaaatggtt gcagacaaaa gtacctgccg tattggaaac agaggccggt
    39961 aagccctctt ttttatagct tgaaccatcg ctttaatcgg caaactacta aagtaggccg
    40021 aagcaccatc tgggcgaatg ggacggtcaa tcggttgatt atcttcgtta tcagaaatgc
    40081 gtgcatcgtc ttgattaatg gccactcgtt caggtgtcaa actagttctt ccaccagctt
    40141 gcccaataca aaggacaaag tcaggttgat aacgattcat ctcttcttcc aatacttgag
    40201 cagatttgtg aaaaactgtc ggcacctcta gccaacggac ctcagcacca tggatttcag
    40261 ctggtaaacc tttaatggcc tccaaagctg gattgacctt ttcccctcca aagggctcaa
    40321 aacctgtcac taatactttc atttctaact cctcaaaacc aatttattta ataaacggtt
    40381 gagctctgtt ctctcagact ctgttaagat actttccatc tcttccttaa ccttgatatg
    40441 ttgcagaggg ggattcacca ctaactgctc tttggcatac ttcgtagcct ctaccaacac
    40501 ttctcactga ttttcaggat tgcgatgacg ctccaccaaa ccttccgttt ctaaaatctt
    40561 gaaatgtcgt gtcaaagcag cctgatcaat cttcaaacgc tcctgaactc ccatttgatt
    40621 acagggagaa ttctccagca aaaacagtaa aatctgatac cgtgtcaaac taatcccaag
    40681 ccttttttca aataattgcg tgctcgcttg ctcagacaag cggagttgat aaagtaaatc
    40741 ttgaatctct aacatctctt ttctcttttt cttgattcat caatagttga ctaatcaagt
    40801 ataatgtaaa gtaaaataga ttgcaagaat gttgcttgag tcattacaag attcttactt
    40861 cttccattca aattgacaaa gaaaaaaacg aacgagaatc gctttccatc acgaaagcta
    40921 gatctcattc gtcaaaatga tgttatcaag tcgggtttat ccattcattg aaacgtgaac
    40981 gtgatcatag tgattttctg tcacactacc acggtctggc attgggttcc aagtgttagc
    41041 tggcccatat ttgctatcga atggagcata gaaacgttgt ttccagatga tgtaactaat
    41101 gccacggctg gccatgtttt gaatagcata ttccgcaatc ttatctccta attctgaact
    41161 ttctggtacc ataaagtcga tagccaaacc ttttccatga tctccactgt ctcctggacg
    41221 ataaccacta aaggatgtaa tgccaaacaa gttagcaatt tcttctttaa aggcagctgt
    41281 ttgtggttga aggcctgcat tttcagattt tgctactgca agtccagcat aatcgggcgc
    41341 agctggagcc tcgtaagttg ttgaaattat tttcgtctct tctggttgat aagtagaaac
    41401 tgctgctgta gctccatttg atgatgctac ttcttttgct tctgaacttg ttgtagttgc
    41461 ttctactgct gatgcagctt gagggcttgc ttgtgtttcc tgcttctcag ctggagtcgt
    41521 ttcctgagga gcttcttctg caactacact gcttgtttcg gccgtttgct cctctgggac
    41581 agaagtgccc gtagatggtg ccacttcttc agaagcaatc actgtctttg taacttctga
    41641 acttgatgct acttcttttg gagcttctgc aatcggttga gaaaggtctg caacctgaac
    41701 agtttgatca tcaacggtca cttgattagt ggtcaaatct gctgtcgcag ttgtcacttc
    41761 ttcactagag tctgcttgag gtgtttggat ttcaacttct gttacttctt ctgcttcatt
    41821 gacagtcgtt gtcaaaacag tttctgggaa aatcaagtcc atattagtga ttttgttcag
    41881 attcgcaagc actgtgacat ctacacccaa agcttctgca atggtgctca aagtatcacc
    41941 atactgtact gtataacttg ttttgttgtc cgttttagtc aaatcgtttt ggatttgctc
    42001 tacactacgg gcagtccaaa gaacttcttc tgcttgagtt gccaatactg gggcaaatga
    42061 caaggcaact gttgacgcta ataacattct tttattcatt ctttcaaatt cctttcaaat
    42121 gagtacctgt ctatgataac acaaaaaatg cagaaaaaaa gccctctcgg gcctatttaa
    42181 caaaattgtc tattccttgt aacaaactag gttacttgaa atagtttgtt aggtctctgt
    42241 cacaaaactg acacaatctt tttgtcgctc agcctcaaaa atacgggaaa tatctgctaa
    42301 cgcttgaatc ctgtgtttcc cttcataagt cgactctaaa aagttgatac tttgaatccc
    42361 actattctgg gcaaattcca catccagagt ccgatcccct atataataag tattatcaga
    42421 attcaactga tacttattta gcagataggt agccgcttct ggacttggct tccgcacaaa
    42481 gccactctga ctggttaaaa tctctgtaaa ataggattcc acccccaagt ccttgagaat
    42541 ggtaaaagcg ttgttcccct tatgagtata tataaactgc tgaattcctg attcgtctgc
    42601 ccaagctagc acctcacgcg cacctggcat caaaactacc tgagcattct tctcagccat
    42661 actctgggca cgcacctgat ttagcacctc aacatccaga tttctatctt ctgccacccg
    42721 cacaagcaaa tcttgcaccg aatacttgaa gataaactct ctcaccttct ccttatcata
    42781 aggaatagaa aactgagcaa aagtctcctc aatccctgat aaaatcgctt cgtaagagtc
    42841 caataaagtc ccgtctaaat cccaaataaa agctgttttt tgcatttcct atcctttcaa
    42901 gatcatatag cgctggtaac gatagcgtag aaataaccag cgaaaaccat tatccaagag
    42961 agaccctgcc caaataccag gtaagcccca accaagcaca atccccatca gatatcctgt
    43021 tccaatgcgg atacaccaca ttcctatact tgtcgcataa aaagggaggc gtgcatttcc
    43081 taatccctgc cagactgccg tatagatgac tgttcctgtc gtcatagagg ttccaagtag
    43141 tgaaaacagt gtcactagaa cactagcctc caccgctaga gaatcagtcg tatagagatg
    43201 agttaatggt acacccaaga catatatact aaaggacagg ggcaacatga ggaacagaga
    43261 aagccaaaag gtttgtttac tcaaactagc gactcttttc caatcatcct ctccaactgc
    43321 tcgggccaac agcatgaccg ttgccgtagc gacgccaaag gcaggcatat agttaaactg
    43381 ggtcaagact tctccgattg cattcccagc aactgcctcc gtcccaaaag aaacgaccaa
    43441 ggcaatgatc actacatctc cagccctcat cataagtcgc tctccagctg ctggtaaagc
    43501 caaggtcaac agttccttat ctaaaccaaa agttggcttc ccataaggca gttttaattg
    43561 tgaccacaaa atcacaagac caaccaaacg agacagaatt gtcccccaag caacaccagc
    43621 tatccccata tccagaacaa aaatagctag acttgaaaaa agaatattca aggcattgga
    43681 taaaaaacta acatagagag gcagacgtgg attatgcgtt gcacgaatca aggctcccaa
    43741 actagtcatt aaacctaaga gaacaatcga tccgcctacc aaagatagat acagtccacc
    43801 actctcagct acatccctct ccgtccccaa aagtcctatc atctctttcc cagcgaagat
    43861 ggacaaaaat cctaaaagga aacttaatag taaggtaatc ttcaacgcct cagtcacatg
    43921 ataggccaac ttcgactggt ctttctgccc tatgcttttt gaaataacac tggaaatagc
    43981 agctcccaga gcgatgaaaa tcgcttgata aatggtgata atattaccag ctactgaaac
    44041 ccctgaaata gctatcaatc ctaaatgagc aaccaaataa ctgtccacca ttcccattag
    44101 catctgcaaa aagttttcac ccatagctgg caatgcaata ttaagaatgt ctttattttt
    44161 cttaaacaat ctctcctcct gatgaaaaga aactcagttg gtttcccaac cgagtttgct
    44221 ccctctgtct taaagtccta aataagcctc aaccgctgct tgcatgtcag cagctgccac
    44281 tgttgtcttg tgacgaattg gagctatttc aagcccatca actgctggtg gcactgcaac
    44341 gcctgagatt tcatgtaatt gagccaaggc ttcaaagtct gttaaacctg cttttccagt
    44401 tacagcttct actgcaacta ctgggaactt gtatggacta gctgttgaag caatcactgt
    44461 cttagttaca tctccagtgg ccgattggta ttttttataa actgctgaag caacagctgt
    44521 atgagggtcc tcgatataag aatatgactc acaaacacgc ttgatctctg ctgccgtttc
    44581 ttcctcagtc gcatattcag ctgcaaagag gtccaaaatc tctgcatcaa agtctgtcaa
    44641 cttatattgt ccttgcgtgt tcaaagcatt catgagttca gctgtctttt cagcattatt
    44701 tcccaaaaga tggaaaatca agcgctccaa gtttgaagat accaagatat ccatagatgg
    44761 gctggttgtt accttaaact cacgtttttt gtcatagaca cgtgttttaa agaagtctgt
    44821 caaaacattg ttgtcatttg aagcacagat caatttacca actggcaaac caatttgttt
    44881 ggcataaaag gcagccaaga tatttccaaa gtttcctgtt ggtactgtga agttaacctt
    44941 ttcaccagct acaatttcac cagtcttaac caattgagcg taagcataaa cataataaac
    45001 aatttgtggc accagacgac caatattcat agagttagca gatgaaaatt gcaacttgtt
    45061 ggtagtcaat ttttcacgaa gagccacgtc gttaaacatg tgcttcacat ttgtttgcgc
    45121 atcgtcaaag ttaccatcaa tagcaataac atgagtattg tcgccagtct gagtggtcat
    45181 ttgtaactct tgaatcttgc tgacaccatc ctttggataa aagacgataa tctcagtacc
    45241 aggcacatcc gcaaaccccg ccatagcagc tttccccgtg tcaccagatg tcgctgtcaa
    45301 gataacaatc ttgttctcca aaccatgttt cttagcagca gtcgtcataa agtatggcaa
    45361 aatagacaag gccatatcct taaaggcaat cgttgaacca tggaaaagtt ccaaattgta
    45421 ttgcccatct aatttcacta atggtgcaat agctggagta tcaaatttgc tatcgtaggc
    45481 attgttgata cagtagttca actcctcaac tgtaaagtca tctaaaaatg ctgacaaaac
    45541 tagcttagca acttcctggt aagaagcatc tttcaatttg tcaaagttca aatctacctt
    45601 tggataagta accggtgtaa acaaaccgcc gtccgtcgcc aaaccttgca aaattgcttg
    45661 gctggcagtt actgtattgt tggcatcacg cgttgattga taaactaatg tcattactct
    45721 ctatccttta tctatagtct cgtccattat atcatgattt ttcagaaaat tctcccttta
    45781 taagagaaat tataggctca attcttctct caaaggctgt aaataggtca tttcttcctt
    45841 atttctcacc actagtccct cctcagctag taggagtaag tctttggaaa attcaataat
    45901 cgtagtttct tcctcatctg taagattttt cttagaaaat tgtctcctta aagacttgta
    45961 atcataacca aatactttaa agaaaggtgc tgtttctaag taagcttcta acttgtctaa
    46021 attaaccaat aatcccaagt gaaaagctgc agaagcaaaa gtcctatcaa gtggctgtgt
    46081 acacacacta cgaaactcaa ctgttcctcg agtcgttaag tcttggtact ggtaactacg
    46141 atgagtttca aaatccttct cttgggggta aataataacc tcatccccat tcagagcaaa
    46201 tgcttggatt tcaggcgtag ccaaatagtc cccagcctga ataggataaa aataataggt
    46261 ctgcccatca cgttccgcag taaaaatcgc agaatgattt agatagtcaa aaaaatcagc
    46321 ttcatcatta aggagtctag cattgacccc aacattctct ggatagatac catgcataga
    46381 ttcttcccag aaaatatccc ttgaaatttt cgtatcccaa tccgcacccg aaaactcaga
    46441 gtttgcaaat aaataagcct tagccgcttc aatttgagta aaagcattaa tcacccgcaa
    46501 gtagttggtt tttgaaatat ccagctgaac ctggctccca cagataaaag taccgtattc
    46561 agggaaatga tgtaaatctg atttaataat atttctactc aaattcaaat aatccatcaa
    46621 catctgatag cgtggataag ccactggaca attctcattt ttatcccagt tgggatggat
    46681 accacagcca acaatagcat gatttgattc agctaacttt ctctgaatta cattcatata
    46741 attattgaaa cgattttcga cctcttgaat cgtttcagcc ttaccaaatg caaactcaat
    46801 cgttgtatag gaaacttcaa ataaaatagc atcctgactt atcggatcta ctaactggat
    46861 cagattgcca aaatcatcta cctttgctac ggtgagatcc aaagtagaaa ctaaataatg
    46921 aaatagatcc tttataactt caacatctgt agcatcccct tctaaacttg caacaggata
    46981 ctccaactca attccgacaa acaattcagg attttcttta atatttttca aataccgatg
    47041 ttttaataaa tcgatagaac aagacatact cccctacact ttcttaatct aaataaaatt
    47101 tgaataacta taattatacc aaaaataata taaaaaagga acgaagaata acaacgttcc
    47161 taacactata ctataccggc ggccggggtc gaaccggcac gtccttgcgg acactggatt
    47221 ttgagtttga ttctatgata ttcttaactt cataaatcta gtaaaatcaa attttcaata
    47281 aattatttct atcgcaaaaa cgatagattt tttcttttta gtaacatttt agtatttgat
    47341 agcttgctca ctatatttaa atactgttct tttctcttca aaaaatacct tacacttttt
    47401 cacttcttca tcataggcag taaagagttc ttctatttcc caatcgttat aactataatt
    47461 tgatttattg ctaagatttg taagcaggtt cattaatgaa aaaattttct ccactcttgc
    47521 agttgatagt ttcttaaagt atacttcctt gtcattactt gtatcagtag aggaataatt
    47581 gaactcttgt tttagattaa ctgtttttat agtaatagga ctagtgaaaa attcctttat
    47641 ttcttcgccc ttttgttcta acgccccaaa aagttcttta atatcagctt ctgaaaaaga
    47701 atactttgat ttatcacttt gatttctcag tatatttaag attgaaaaaa ccttagtcat
    47761 ccttgcttct gacaatcttc taaatttttc atttctagtt tccatagttt ctccaataag
    47821 taaattttat ttctttatcc tatatattat catatagcga gatttttttc aaatattgca
    47881 ttttatgatt ttgtgtagta taatatccta tatagaggga tatcctctaa atataatacc
    47941 caaaaaggag gggttcttat gtttaaagaa cttatcgaat ttgttaattc ctcaacagag
    48001 ggacagttta aagcctttca agtcaaggct aatgcaataa caggagatgt tatcatctct
    48061 caaaatgtaa cacctatcac tgacgcctta aaaaatcgtc taggattaaa aactgtgcaa
    48121 acctctttag caaggaagtt agcttacgct tctactcgtc gccactataa agatggtaca
    48181 acaatgatgg aagacatctt agctggcaag acacgtcgcc atgcaaacag ctacatctag
    48241 atgactgggg gagctaactt ctccccttta tcttttgatt gaaatagaaa ggagtgacat
    48301 catgaagagt ctctataaat atctttttta tttgttcttt attggatttg ctggcacact
    48361 ctgttatgtg ttgcttttaa caaatgcctt ttcacctatc tttgaagctg ctacaatatt
    48421 gatggagatt atagttgtta tttttttaat aatctgtata gacctgattg cttcccctac
    48481 tggttctgct gaggagaata taaaaaatga gaatgttaaa tcaaacaatc cgtgtgaaga
    48541 gtaaataccc ttacttgatt cgtcctcgaa atattaccat tactagacta tctatccaag
    48601 tttttctttt tttactattg gtatcttcat ggcttgctgc aatcccattt attgcacgtc
    48661 tagtcttttc catgtttttt ataagtcttc tttttttagt agagaggttc tttcattctg
    48721 atgttataga aaaattgaga aacaagctca atatcagaga agctttgttt tacatgttaa
    48781 ttagtttaac tttatatgat gatatagata atgaagtagt agatacagcc gttttatatt
    48841 ttgacgtttc tgagaatgac aaggttatta tctgtgtccc attatttggg aaccgttatc
    48901 tgaaaacctt gaaaaattta gaggaatatc tctgtcccac attggggttg tccttaattt
    48961 ttaaaaaaga agagattgat aaaatagtat atgtgttagg gaagatagaa gaaattgaac
    49021 aatacgtttt caatactaat acattaacta gggagttttt taaggatatt cctagtccaa
    49081 taatcaagct atcaaatacc caacaattct ctctgaaatc gaatactaat atcggtattt
    49141 atggacgcac tggaacaggt aaaacaatag ctctccaatg gtatttattt aatgctcttg
    49201 ctaaagggtg cggaactgtt gacggtactt acttaggcat tgtagacgga aaaggggcag
    49261 acttatatgc attagggaag ctacttgaag aagaaatagg aaatcaagtc actgtgggta
    49321 cttctccaac ctctttagcg aaattgtcaa gggaatttgt agaaattatg aacgaacgtt
    49381 ttgaggttat caagcagaac agttccctaa atgctgatgc ttatgattta ggaatgatac
    49441 ctaattttct atttgtagac gaattggcat caatacgcga tagttgttgt ggctctagca
    49501 aacaggcgaa agaactttgg aatgaaattc tacaaaattt aggattgatt gcccgtaaag
    49561 gaaggcaggc tggttgtcac ttagtattat ccacacaaga ccctaatgct gagaatattc
    49621 cagtagaatt gagaaatcaa atatcggcag ttttatacct tggaggtcca ggtgctgata
    49681 gattgaagat ggcttttagc atgtgcgaat tagaaaacgt tcctactgta tccgatagaa
    49741 aaggagaggc tctcttttat gctgacggtt taaattcagt tgagcctgta ttgacaatcg
    49801 ttccattcgt tgacgtaaaa accaaacaag aatttttaca gatagttaaa aatatactgc
    49861 caaactacta atgacggtat ttttctctgt tggaatagga attcttttca atagagaaaa
    49921 agagccaacc gactgcattg caggaggtaa gaaagaaagg aatttatcat gaaattaaat
    49981 gattttttga aacccgaact actaggcaat cgcttctttg ccgtgaaagg gtatacagaa
    50041 gtattagaca gagagactaa taaacccgta gctttacgac ttaatgtgtc aattcaagat
    50101 gagaattctg atttctttat ggagatgata caagtcaaaa taaatacatt atcgcctact
    50161 gcttctgttc aagagatggc gaacaacaaa acttgtcctg ttagtcttaa agatttaaac
    50221 gtagggcaat tcaatggaaa tttgtggttc gcttgttctg atgttttacc tgtaacaaaa
    50281 tagctaagat taaataatat ataaaggagt tttacaatgc aaacttttaa ctacgatgat
    50341 tttaagaatg aaaaggggat tgtttcattt tctgaagcag aacaaatcta ttctagtctc
    50401 cttaattctt ccaatcaact tgataaagaa tttcaagaag aatggacaac atttgtactt
    50461 ctatgcgtag agtatgcctc tgcacgtggt aaatggctca cactctcaag agaagagaaa
    50521 cttgccaatg atgaatctag aactgttact cacaataaag ttatttatca actaaagatt
    50581 ttaaaaggtt tagcaagtga acagggcaat gatgttgctt ggtttgaaca atttaacgat
    50641 gacagaaaac gtattggcga ctttgcttgc tatgtagctt atatctatgc cttaaatgct
    50701 cgatagacaa ttagaggata ttatagctat atattactct atgtctgata ttcatggaaa
    50761 ttattaaata acatcttaag aataattaat tctatttatc tatcaccgaa acaatgtgct
    50821 ataacttaat tcgattctta gactaatatc aaaaataaag aggggaatat atatgaagac
    50881 gttattaatt ggtgatttac acttaaaatc tcaactgatt ttacccattg ttgacaaaat
    50941 tatccaaaca cataatatta agagaatcat ttttcttggt gattacgttg atttacatgg
    51001 tcaaactaac aatatccaac tttatgccaa agacctcact tttttatact cttggaaaat
    51061 agataaagag caaaacggaa tagatgtaat taatcttata ggtaatcatg atgcttatta
    51121 tttactggga gaacaagctc ctttctcaat tcaaaaccta gaggtctttt tcgcagttaa
    51181 agaattgttg caggatttga aattacaagt agcttatcaa ctagatgatt atttagtcag
    51241 tcacgctggt ttcaatctga tatttgaccc aaaagaatgg cattttaacc tctataccaa
    51301 agagcatgaa gaagaattag atattctagc ttatacaata ggaccaatgc gtggtgggaa
    51361 agctcttggg gggtctcctt tatgggcaca ttttagagaa ttagaactgc ttcccaacca
    51421 agactttcct aaacaaattg ttgggcatac ccctaaagaa tctattgata tttctaaaaa
    51481 tgttattggt atagatactt tttcattata tattgacaaa gataataaat atcaatttat
    51541 tggtaatgga gatttactcg tttatgacca aggacatttt gaggtcattt caacagactg
    51601 ggcaacagac aaaatattaa aacaattacc acgactataa atttaatagc tacttctcat
    51661 catgtaccta agcaaaactg ccgactaagt cggcaagctg gaagtgtgtt tagcggagcg
    51721 gtgcttagtc acatgataga agtagggagg agcaatgctc ctcttagttt atttattata
    51781 tagacaatct tttggcgaaa gccaacctaa aaggaactat tttttatgac ctcatataat
    51841 aaaaaaatag tccgcacttc ttcctatatt gaaatttggg aatatgaaaa gccaatattt
    51901 tcaaaaggaa aatccatttt agatactgat attaaaagca aagaaaaatt acaacgtaga
    51961 acatttgatg aacttacacc tgaagaacaa gaacaacgtc tggagcgtat gaaaaaaact
    52021 cgcttagaag caaagtggaa cttactccga ttagtcgatt gtaattatga tgacaatact
    52081 tcatttctaa ccctgaccac taaagaaaat attagcgaca gaaaccactt caaagactta
    52141 ctaaaaactt ttataaaacg ctttaactac cacatcttta ataccaagaa aagtaaatta
    52201 aaatatttaa cagtattaga aaagcaaaaa cgtggagcat ggcatgctca tattctgctt
    52261 ttcagcgttc cttatgtacc acaccgtcaa ctcttggaac tttgggaaca tggagcagta
    52321 cggataaata aagttgatgt agacagcaaa gaaaatcgcg gtcgatatgt cacaaagtat
    52381 tttgaaaaag ggattggaca agaattgttg gaaaacttcg gaaagcaagc ctatttttca
    52441 tcacgcaact taaaaaagcc tgatgaagat agattttata cttatgaaga ttttaattat
    52501 gatagttcag tcgtactata tgaaacggaa tacattagta aagtctataa agacggtcag
    52561 tatttcgata atcatgtaaa gtataagaaa ataaaactag attaataaag gagtaagtta
    52621 catgatagca actgttacta agaatgacct agttgccctt ggtttctctg agggaacatc
    52681 taaacgtatt atccgccaag ggaaagagct actgataaca cgaggcttta cagtctatca
    52741 gaataaacga attggtacta tacctgctac tattgtaagc gaattactcg gttttgatgt
    52801 tcaaaacagt accctcaagg agtaaaatat ggcaattaga aaaggtaaag acggtaattg
    52861 gatagttgat attagcaacg gttttgaccc aataacacta aagcaacgta gaattgtcag
    52921 aaagggctat aagacaaaaa aagaagctat tgaagcagaa cactacttac gaagtgtaga
    52981 gttaaaagaa cgcttctatg gggctaaaat aactatcccc atactatatg aactactaaa
    53041 ggaagaagat agtataaatc atcgaaaagc aagctatatc aatacacaag ataataatta
    53101 caacaaacac atcaaagatt atttttctat ggtatataat gtcggaaaac taacctatga
    53161 agacatctac caatttagag aacatcttag gcaaaaagta gctaaaaatt ctgataaacc
    53221 tttaagcaca aacactatca acaaaatcat gattttactc aaaaagattt ttgatgttgg
    53281 tttgcgaaaa ggctattaca cctccaatcc agcaaatttg ataaaaaagt tgccaatcga
    53341 aaaaacaaaa atgcagtttt ggacagtcaa agaatttcaa cattttttaa ccttgtttga
    53401 aactgaagaa tataatatca agttactctt tactgttcta ttctttacag gactacgact
    53461 tggggaagca ttagcactaa catggcaaga cattgatttt acaagcaata caattcacat
    53521 tacaaaatca gtttatgtaa acaaaggaat aagtcatgtt agcacaacaa agactaaagc
    53581 tggaacaaga agaattatca ttaataagaa attgagccat gaactacaac aatggcaaca
    53641 gaaacaaaaa cacctattag aacaatttac tagtgatagc atgaccctac aagtgtttca
    53701 aggctcacct attacaatta caaaaaatgc agttgaaaaa caatataaga aaatacttga
    53761 acgtgatagc acactaaaaa aaatacgcat acacgatttt aggcactcac acgcttccct
    53821 gctgattaac caaggggaag attatctagt tgtaaaagag cgactaggac atgcttctat
    53881 aacaaccacg attgatacct actctcactt gtacccaagt aagcaaaagg atttagctga
    53941 taaactagat gatttactat aaagtaattg agttttataa atggaaagtt tataattaaa
    54001 tcatggatac atcacaagta ataaaagcac atgaagtagc taaaaaagca cactttggac
    54061 aaattgatag agcaggaatt gactacatta aacaccctga aacagtagat agttttgtcg
    54121 caactgatga agagaaagct gccgcctatc tacatgatgt aattgaagat acttcactaa
    54181 ccctactaga cctaaaaaag gaaggttttt caaaaaacat tatagaagcc gtcgatatac
    54241 tcacaaagaa aaaaggacaa gattatcaat cttatctcaa tctagtaaag aaaaatgaac
    54301 tcgctagagt tgtaaagttg gcggatttac ggcataattc agatttaaca agactaccat
    54361 taattactga aaaagactta gagagaaata agaaatacag ttctgctatt agatttttaa
    54421 gagcaaagaa aaaaagttag taactaaact ataaaatttt ataaagagaa aacaaaagac
    54481 aaggcttata aactttgtct ttattactat actggcggtc ggtctcgaac tggcatatcc
    54541 ttgcagatac tacaatttta ttaaaataaa taactataaa aagtgaaatt ttttattgag
    54601 aaaattttag actaggagta taatgtatct aaaataacta ttaggtggct gttatatgaa
    54661 taatgttgtt actacacaaa tttctattca acttagtcaa gagttaaatt ctttattaaa
    54721 tgctattgtt gaagaaaata atacaacaaa gactgacttt attagacaag cttttataga
    54781 gaaaattgaa gatatgtatg atattaaggt cgctgatgaa gcttataaaa aatgggttga
    54841 atgtagcaaa aaatctatct cacatgaaga aatgatgaga cgctatggct aaattatacg
    54901 caatatctga tatacatgga tacttggatg aattcagaga cgctctcaat aaagtaaatt
    54961 taaacgataa agataatcgc ctatttttac taggagatta tcttgataat ggacttcaat
    55021 cttttcaagt catttccaaa ataatcgaac ttgaggaggt ttatcctaat caaattatta
    55081 ctcttctagg gaatcatgaa gaatggtttt atgattggtt gattttagat aaacctactg
    55141 cttcagcatt tccagaaaca ataaaaagct tcttctctcc agagaaattg aactatattt
    55201 ttaaatcgaa tgctaacaac tttgaaacag atgttagaaa tgaaattaaa aataatatca
    55261 aattcaaccc atttataaac tggtttaaaa aacgatatag ggatgaacgc tattatgaaa
    55321 ccgaaaccca aatttttgtc catgctggca ttgatgaaga agcagaaaag ctttggaaag
    55381 aactaacgag ttcagagata tttacaaaca aatttcttat taccactggt agatttcata
    55441 aagctattat ttcgggccat attgcttctt gggaagtagc taaagataga agatacctag
    55501 gtaagattta ctatgatagt aaaagtcatt actttattga tggagatgta acgaatagca
    55561 aaacaatacc tgttctttac tatgatacaa ttacccaaaa atatcacttt ctataacttt
    55621 gaactgcacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt tattatgaaa
    55681 ttgagttatg aagataaagt tcagatctat gaactaagaa ag
//
LOCUS       DAVFJR010000009        52191 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVFJR010000009 DAVFJR010000000
VERSION     DAVFJR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.009"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(136..1263)
                     /locus_tag="VU722_000739"
     CDS             complement(136..1263)
                     /locus_tag="VU722_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1771757.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(1978..2529)
                     /locus_tag="VU722_000740"
     CDS             complement(1978..2529)
                     /locus_tag="VU722_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771758.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(2778..3602)
                     /gene="nadE"
                     /locus_tag="VU722_000741"
     CDS             complement(2778..3602)
                     /gene="nadE"
                     /locus_tag="VU722_000741"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU1771759.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(3599..5059)
                     /locus_tag="VU722_000742"
     CDS             complement(3599..5059)
                     /locus_tag="VU722_000742"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU1771760.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(5175..5663)
                     /locus_tag="VU722_000743"
     CDS             complement(5175..5663)
                     /locus_tag="VU722_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771761.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(5653..5862)
                     /locus_tag="VU722_000744"
     CDS             complement(5653..5862)
                     /locus_tag="VU722_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1771762.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(6248..6427)
                     /locus_tag="VU722_000745"
     CDS             complement(6248..6427)
                     /locus_tag="VU722_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771763.1"
                     /translation="MMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTII
                     LLCFFTLKKSKKYSF"
     gene            complement(6760..6969)
                     /locus_tag="VU722_000746"
                     /pseudo
     CDS             complement(6760..6969)
                     /locus_tag="VU722_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6985..7830)
                     /locus_tag="VU722_000747"
     CDS             complement(6985..7830)
                     /locus_tag="VU722_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771764.1"
                     /translation="MEVINVSKHYGHSIILKDINFALNKGEIVGQVGRNGVGKSTLMK
                     ILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLI
                     QELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVL
                     KNLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSAT
                     DRDIFITKQEFGDIVQEEGLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIY
                     LNRSK"
     gene            complement(8213..8941)
                     /locus_tag="VU722_000748"
                     /pseudo
     CDS             complement(8213..8941)
                     /locus_tag="VU722_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(9201..9512)
                     /locus_tag="VU722_000749"
     CDS             complement(9201..9512)
                     /locus_tag="VU722_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771765.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(9527..10813)
                     /locus_tag="VU722_000750"
     CDS             complement(9527..10813)
                     /locus_tag="VU722_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1771766.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDNIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            11437..11619
                     /locus_tag="VU722_000751"
     CDS             11437..11619
                     /locus_tag="VU722_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU1771767.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            11629..11991
                     /locus_tag="VU722_000752"
     CDS             11629..11991
                     /locus_tag="VU722_000752"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU1771768.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKTGVKSK"
     gene            11988..13178
                     /locus_tag="VU722_000753"
     CDS             11988..13178
                     /locus_tag="VU722_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU1771769.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSIEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIADHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(13359..14585)
                     /locus_tag="VU722_000754"
     CDS             complement(13359..14585)
                     /locus_tag="VU722_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU1771770.1"
                     /translation="MAKTRYSGVFVDTKGKYFYETELGIDRISGKRIRKKSRKDSNGK
                     PFSTAREAYLELTRVKREYHKAHTYANYNMTVKQFILDCYIPYYKSYVEESTYAVRIK
                     NLEKIAERFYNKTLRGLTIEDIQNYRIWLLSSKDENGSGYSQAYASLIFGMFRKSLDY
                     AVEMGYLETNISKKAKAIPKGKAIVPYWTKVEFERVIAQICLDDFYEHLNFVMLWTFF
                     MTGIRVNEGMALWWNDIDFDKKRMRVHHMLILKSRKNWQRNAYTKTSDGKRIISLDDD
                     TISILKRWKDRQKEIGLGNETDFIFTYDSLPMIKSTLARIIQRYSELANVKRIQGKGL
                     RHSNASYLINEFNVSVLILSKRLGHSSPEITLKHYSHLWRGADESIAEIMSGNISIHT
                     APKTKIQFNGNQNLKR"
     gene            complement(14589..14783)
                     /locus_tag="VU722_000755"
     CDS             complement(14589..14783)
                     /locus_tag="VU722_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU1771771.1"
                     /translation="MKPLISKDDLIKLGYKKHTAISIIQAVKQDLVYNKGIPFYNNRR
                     LGLVPRERVENLIGVKLDEE"
     gene            complement(14791..15603)
                     /locus_tag="VU722_000756"
     CDS             complement(14791..15603)
                     /locus_tag="VU722_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771772.1"
                     /translation="MTRELYNTKIIQYNSNTFEVIYYRKAKFRRLGETDTTVSNTSKS
                     PSEKELYQQANRIKRRIRHYMLCNDFDLFWTLTFNDEKINSHDYLIVKKKIRTWLKAQ
                     REKYGKFHYIFIPELHKNGRLHFHGVTGGFSPKLTKARNTKTGRLINKNGKQVYNVDS
                     YQLGFSTVTKIDSSEKVANYITKYITKDLLAIPSGYKQPKYFSSRGLIKPIVSYENLE
                     RNYFEGLTPSFSVGHLDNLEYKEDIAIYNLSIDDNEEIIQNSTDTRIKIRKE"
     gene            complement(15707..17116)
                     /locus_tag="VU722_000757"
     CDS             complement(15707..17116)
                     /locus_tag="VU722_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEU1771773.1"
                     /translation="MIVSKIKRKLSKYDCREYTPTYLSVSETIESRKERQYSLIKKLL
                     KVFLISVIITFLSSHFPLLSTIYKISIVISSVLLDIFIWYIVVKFLFSTYSPIWKYRF
                     LSILRLATERLDLIQLPSNKIQIKTVEWKFYKENERIIIELNPSGTIPNIQQVKEITR
                     RLTEFLIQATNEDWNILESTVQNSYVVIKYGKSNPRYTVSELFKITDEDYYINYKPIK
                     LYDNICFDIASEANQQIIIAPSGAGKSLYLATLAGLLIKQGHSISLIDAKQTSLGATF
                     ENLGIPVARNAEEIILLLEQMVFEMEDRYKRYFAFSSVDFGTTYKHFSLPAHYLIFDE
                     VLAALECGTSAQQKEMVRLLKILALKSRASGQGLLVLASQKLLASDLPRAVTEQCQTR
                     IILGNSSSISEETFYSVMGKEKIDLLAEYRGGVGKGYILTPKTNGIKYFETPYFDLDS
                     IDFKNKIRDFQTIPRKQIE"
     gene            complement(17113..17550)
                     /locus_tag="VU722_000758"
     CDS             complement(17113..17550)
                     /locus_tag="VU722_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771774.1"
                     /translation="MENNFGKVSFNSPSLKNLLIGTSNVEHTPTSAFVIECRDVPKRN
                     EKNEVIDGTISKKVLLALQSEIVKAIQEVGGDLSSIKPFTIEIYNDESFLKKINNELI
                     IAKTIDLEGALLALKWVSDGRNGGAYREFKLIISEIKLSGAKS"
     gene            complement(17735..18421)
                     /locus_tag="VU722_000759"
     CDS             complement(17735..18421)
                     /locus_tag="VU722_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771775.1"
                     /translation="MSSKQFNNLCKQKFPNSCHFIFKKCSQRIQKKYKDLKLKRHIDL
                     HSDEKLIGKILNYSNLSDLSRNNPYLITPSVLNYFVNEEHYFNDENEVLWGRDIDEYL
                     EDFFIEMILDIQGIPEYSKHLLNLSLTNTGDIKEYFQQHFPLASSSYNELKDKFIDFT
                     YNQFDTIEILENDSVFLFRKKDSVTLSPKNKESYLSYQKLPEKLDLLAKYILLPMIDK
                     LTLESLIYRK"
     gene            complement(18426..18641)
                     /locus_tag="VU722_000760"
     CDS             complement(18426..18641)
                     /locus_tag="VU722_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1771776.1"
                     /translation="MISYKPFYETLFKQGKTEYELIFHHGLSSNTLHRMKKGKPITTA
                     TLDTLCFILNCNVYDVITYIPDDIEEV"
     gene            18756..20120
                     /locus_tag="VU722_000761"
     CDS             18756..20120
                     /locus_tag="VU722_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771777.1"
                     /translation="MKLEDFQTFPFKSVQEYISDKEKAIKFSFLLQGDEPDRSELMKL
                     IYKDIFEWYDDKVHSGDTLITYRTAIFRKYYGKSYSKLSRDKQREILNIIKSYTEYDD
                     DFPFEFELDNKEKNVYQICNNYQIGNFGIFPKGRINPKRAQSPYNDYFDLTLSVIWDL
                     YDGTLTPDDEFKRAILDEKEYFDQFKDFETFLSDNFLTVFFDDEGYLIRLSEIDDFEE
                     YVRISNQIIYTRGLAILTYLQSMYDDNSELPTQQLEEKKTVPRPTTKELAHRTLKIAE
                     EEIDKISKFDEYYNELEFNLHKEKFETTKKRIYGAIVLFLFIVSLFFYTSEIIMFIWI
                     LSTVLYVADKIRIVKEKIKYDKIINATQEKYREEKKKLLSTLRKEYYSIPTEFRTYNH
                     ISGIQYFLNADIASNLQQAIHYYSNEYNSKRMQDQIYSLHHSNTILQDRIKELELERE
                     LEKY"
     gene            20141..20533
                     /locus_tag="VU722_000762"
     CDS             20141..20533
                     /locus_tag="VU722_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771778.1"
                     /translation="MTKFNLQSNQIYSELSKFEIEEILYNATKQLNGSVERQSSEEIS
                     YSGQGNFFDYMKHPGLSRYTCWQVLVTISDLGDKRKVELTAVGESPISYLLNNFLSFI
                     TFYTLFQRHRNLNFGISKEKAKYLSNLL"
     gene            complement(20719..22281)
                     /gene="guaA"
                     /locus_tag="VU722_000763"
     CDS             complement(20719..22281)
                     /gene="guaA"
                     /locus_tag="VU722_000763"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU1771779.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREINPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPSDFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIQK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRVLGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            22423..23121
                     /locus_tag="VU722_000764"
     CDS             22423..23121
                     /locus_tag="VU722_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1771780.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(23164..24060)
                     /locus_tag="VU722_000765"
     CDS             complement(23164..24060)
                     /locus_tag="VU722_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU1771781.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLIPLKDLFLEK"
     gene            complement(24069..25004)
                     /locus_tag="VU722_000766"
     CDS             complement(24069..25004)
                     /locus_tag="VU722_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU1771782.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKVGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(25001..25726)
                     /locus_tag="VU722_000767"
     CDS             complement(25001..25726)
                     /locus_tag="VU722_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU1771783.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(25810..26445)
                     /locus_tag="VU722_000768"
     CDS             complement(25810..26445)
                     /locus_tag="VU722_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU1771784.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLHGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQMEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(26447..27274)
                     /locus_tag="VU722_000769"
     CDS             complement(26447..27274)
                     /locus_tag="VU722_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1771785.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAKTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYKRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(27296..28353)
                     /locus_tag="VU722_000770"
                     /pseudo
     CDS             complement(27296..28353)
                     /locus_tag="VU722_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            complement(28496..28687)
                     /locus_tag="VU722_000771"
     CDS             complement(28496..28687)
                     /locus_tag="VU722_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771786.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIAIGAIRDLWRYSC"
     gene            28876..29487
                     /locus_tag="VU722_000772"
     CDS             28876..29487
                     /locus_tag="VU722_000772"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU1771787.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            29533..30261
                     /gene="rlmB"
                     /locus_tag="VU722_000773"
     CDS             29533..30261
                     /gene="rlmB"
                     /locus_tag="VU722_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU1771788.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNLEKVKELAT
                     EKKVSISWISKKSLSEMTEGPVHQGFVLRVSEFAYSELDCILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(30300..31211)
                     /gene="trxB"
                     /locus_tag="VU722_000774"
     CDS             complement(30300..31211)
                     /gene="trxB"
                     /locus_tag="VU722_000774"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU1771789.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(31277..31501)
                     /locus_tag="VU722_000775"
     CDS             complement(31277..31501)
                     /locus_tag="VU722_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU1771790.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(31579..32322)
                     /locus_tag="VU722_000776"
     CDS             complement(31579..32322)
                     /locus_tag="VU722_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1771791.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(32322..33122)
                     /locus_tag="VU722_000777"
     CDS             complement(32322..33122)
                     /locus_tag="VU722_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1771792.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMDISAPDTVQTDVKGDLR"
     gene            complement(33280..33636)
                     /locus_tag="VU722_000778"
     CDS             complement(33280..33636)
                     /locus_tag="VU722_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU1771793.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(33630..34160)
                     /locus_tag="VU722_000779"
     CDS             complement(33630..34160)
                     /locus_tag="VU722_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU1771794.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(34160..34654)
                     /locus_tag="VU722_000780"
     CDS             complement(34160..34654)
                     /locus_tag="VU722_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771795.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            34789..35235
                     /locus_tag="VU722_000781"
     CDS             34789..35235
                     /locus_tag="VU722_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU1771796.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYINQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            35232..35879
                     /locus_tag="VU722_000782"
     CDS             35232..35879
                     /locus_tag="VU722_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU1771797.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMITGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(35900..36481)
                     /gene="pdxT"
                     /locus_tag="VU722_000783"
     CDS             complement(35900..36481)
                     /gene="pdxT"
                     /locus_tag="VU722_000783"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU1771798.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(36482..37357)
                     /gene="pdxS"
                     /locus_tag="VU722_000784"
     CDS             complement(36482..37357)
                     /gene="pdxS"
                     /locus_tag="VU722_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU1771799.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLRKDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(37509..38888)
                     /locus_tag="VU722_000785"
     CDS             complement(37509..38888)
                     /locus_tag="VU722_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU1771800.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            39183..40106
                     /locus_tag="VU722_000786"
     CDS             39183..40106
                     /locus_tag="VU722_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU1771801.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            40166..40771
                     /locus_tag="VU722_000787"
     CDS             40166..40771
                     /locus_tag="VU722_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1771802.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDVIFDDFRIFVKITEKLRNAQELLRKDAEEFNWENL"
     gene            40789..42033
                     /locus_tag="VU722_000788"
     CDS             40789..42033
                     /locus_tag="VU722_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1771803.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(42150..42407)
                     /locus_tag="VU722_000789"
     CDS             complement(42150..42407)
                     /locus_tag="VU722_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU1771804.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRVV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(42449..44485)
                     /locus_tag="VU722_000790"
     CDS             complement(42449..44485)
                     /locus_tag="VU722_000790"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU1771805.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTLKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(44745..45662)
                     /gene="glyQ"
                     /locus_tag="VU722_000791"
     CDS             complement(44745..45662)
                     /gene="glyQ"
                     /locus_tag="VU722_000791"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU1771806.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQCCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(45855..46616)
                     /locus_tag="VU722_000792"
     CDS             complement(45855..46616)
                     /locus_tag="VU722_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU1771807.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QPVIWSDFNAATQIIRESAVPTYTNNRRVVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLHIVGHELAHWSEHFLDDFDGSDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTDKTLPLLNWFVQQKLIEKEI"
     gene            complement(46889..47731)
                     /locus_tag="VU722_000793"
     CDS             complement(46889..47731)
                     /locus_tag="VU722_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU1771808.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(47845..49236)
                     /locus_tag="VU722_000794"
     CDS             complement(47845..49236)
                     /locus_tag="VU722_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU1771809.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYGIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(49471..49848)
                     /locus_tag="VU722_000795"
                     /pseudo
     CDS             complement(49471..49848)
                     /locus_tag="VU722_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            50081..51058
                     /locus_tag="VU722_000796"
     CDS             50081..51058
                     /locus_tag="VU722_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU1771810.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGKQVQLPIQQAPHT
                     MTEEVAAFSHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            51055..52137
                     /locus_tag="VU722_000797"
     CDS             51055..52137
                     /locus_tag="VU722_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1771811.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLNNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT        16072 a        10916 c         8913 g        16290 t
ORIGIN      
        1 ctgacttcaa cccactacag ttgacaaaga gcccactttt ttatagtcgc tataagatga
       61 ccttatctat agctttttat atataattat atattcagac atactattat caattttgtc
      121 gcagggagga atctgttaac gcacccattc accattatca ttgactctat agccatctat
      181 acttgtattg accgctaact cacccgatgc atttacataa taccatttac caccaacttg
      241 gaaccattga ttaactttca tagaaccgtt gctgttgagg tagtaccatg aaccattaac
      301 ttgtacccaa cctgttgcca tggaaccatc agtattataa aaataccaca taccattttc
      361 ttgtttccag cctgttgttg gagcaactgc tttagctggt tctactgcta catctgttcc
      421 ttggttagat gtaacagata caggatacga aggaatagat gattgctcag gaacaacaac
      481 tttttcaggt tctctcgtcc ctctccttat acgtcttttt accatctctt tagtaatttg
      541 acgagaagta gtttcttcaa ttgttccatc acgttcatct acagcataga ttgtagtaag
      601 agtaatttta ccaatttctc ctacttcttg acctttatca agagttgggc catcgagata
      661 ttctgtttcg attggaattt cttggacaag aacttggggc ttggttcctt ttttaacaac
      721 tcttgtttga gagtcttttt tttgacttaa agtactctca gttacttgtc cactctttcc
      781 atctacatca taagttatcg ttgtaactgt tttcccattc tttcctagag taatctcttg
      841 ctcctgtcct gcagaaaggt cattgtctgc ttcatattta gtagcaaatg gaacaagaac
      901 ttcttcaacc ttgcttttag ctggaacttt gataactgta tccgtggctt cttttctatc
      961 aacagtaacc tgttcggtaa catgaccagt ctctggatta acatcgtagg tccttgtcgt
     1021 agttacatag ccatcctctc catcaattgt aacaggattt tcactacggt cttttgtttc
     1081 atctttttca taacgaattc gcgtacttga aattttcttg gttactacct taggtttagt
     1141 cgctactttt acaataatat ccccattgtc agcgtcatca tactctattc cctcttcttt
     1201 atctctagta tcatctctga catattgaat cccatcagca gcatgaacaa aacttgtatt
     1261 cagattcctc ctaaaaataa acttagcccg attaccgcag aaccaaaaat ctttccgagt
     1321 ttacgtattg catagcgctt attagtatta gattttgcca ttacatccta cttctagtat
     1381 agcatctttt ctatcaaacg ttaaacaata tactttatat ataaaataga cttagaatga
     1441 tatattgatt attgaactaa cactttaact atatcgtaat caatctcata tataaaggat
     1501 tgcagacatc ttatctaaat acatgctaat atatttagat acaaacattc caacttgata
     1561 attttcactc atctttcatc attccttata caactatgca gtataaatag aatagttttc
     1621 tcatcagaat gagactattt taatattaga taatttgata gaaaaaacat gaataaaatt
     1681 ggttgaattt aattccctaa ctcgatagag gattctattt taaatttaac aacagctagg
     1741 attacactat aaaaagtaca ttaccacctg ttcggctgga gaatctagtc gattagctcc
     1801 ctcttagtta caagcttaaa gcgatttttt aactaatact aaaccagatt aaagaaggaa
     1861 ctagaacatc tgtcttgtac taatcaatat gctattttaa agtttcaaat aaacttggaa
     1921 tgctaattat tatatttaca ataaatagtt gacttcgata gaaacagaaa atagaattca
     1981 acattcttcc ctacttatac cataataaat aagatccgca agatagcctt ttctctctac
     2041 accattaaca atggtttgta gataggacat tccagccttt tccatgacac gacctgaagc
     2101 tgggttgaga ctggcataac gtgctctgac cttttgaaaa cctgcttgag taaaacaaaa
     2161 gtccaagata gctttcaaag tctctgtcat cataccattt ccccagtaag ccttgcctaa
     2221 cacatagcca atttcacagc ttaaatcagc ctcgtctatc ttaacaatgc tgatatctcc
     2281 tatcacttgc tctgggtttt cttttagaca aatggcccat ttataatagt tgagattagt
     2341 ataggaagca acccaattgc aaatcgagtt tcgagtgatt tcgacatcag gatggggatc
     2401 ccaggtaaca taggtcagat tctcagcgga tgaagcccaa ttttgaaaca tggcttctgc
     2461 atcactctcc acaaatcttc ttaaaatcaa acgttctgtc tgtaatattt gcgtaccgat
     2521 agatttcatg atgctacctc acttccttat ttctatgctc gtagtaaaaa ggctcaactc
     2581 agtaacagct agaaaacgag tttgtcttct aatttcttga cgcagtcgct gcctggtttg
     2641 aaatgcgctc tagcaatctt tttcaaacct agtcatcgtt gcaggggtaa gacgatgaaa
     2701 tcgaactctt cgagttaccg aatctgcctc attttcttat ttcaagataa gaggctgaaa
     2761 acctccaatg gaggttttta ctcccaaaag tcatcaaata cagtgatggg taagtggcgt
     2821 ttgtgttggc ctttgtgcca ccagttttca atggtcgctt gagcttctgg gctgattgtt
     2881 ttgccttcta ggtaatcgtc aatctctgca taggtgactc caagtgcgac ttcgtcagct
     2941 aggcctggtt tgtcttcttc taggtctgcc gttgggattt tttcataaag ggctggctct
     3001 gcgccaagtt tctgcaagag ctgttttcct tggcgtttat tgaggcggta aagagggaga
     3061 atatccgcac cgccgtcacc aaacttggta aagaaacctg tgatattttc cgcggcgtgg
     3121 tctgttccaa tgaccgctcc gctatgggaa ccagcaaggg catactgagc aatcatacgg
     3181 caacgtgcct tgatattccc cttgttgaag tctgaaacag gactacctgt cgcttcaact
     3241 gcagctgtca tggcatcagc tgactccttg atattcacaa ccaagctgac atctggctgg
     3301 atgaaggcta gggctttttg agcatctgct tcatcagctt gcactccgta tggcagacgg
     3361 acagcgataa atttgtagct gtcgtctccc gtttcagctc gcagttcttc catagctaat
     3421 tgcgccaaac gccctgccaa ggttgagtct tgtcccccag aaatccctag tacaaaggtt
     3481 tttaggaagg gatgtttttt cagatatctt tttaagaaat caatagaacg acggatttct
     3541 tcctgggcat caatcactgg tttgacaccc agctcttgga taatcgtttc ttgcaaactc
     3601 attcttcttc tccttcacca agggcttcct tgcgcatctt atcaatcaag tccatcttat
     3661 cttgccatac atcacgcgcc aaatccactg gatagtgctg cggattgagc acacgcttat
     3721 actcatccca caacttgtca aattctttac gggcataatc ctgaatgtca gtcaaactag
     3781 gcaagttgta aactaatatt ccttctttga agatatccac caagagagga acggcatcaa
     3841 aattacgaac cgtcttcttg atgtatgtat aggtcggatg gaacatcttg atttctgtca
     3901 tgtcgctaat atccacacca tcataagtga tatagtcgcc ttctgacttg cctttttcac
     3961 gactggtaat gcgccacacc tgcttcttac ctggcgtaga gactttttcc gcattattag
     4021 acagcttaat cgtattgcgc atctgaccag tttcatcttc gattgcaaca atcttgtaaa
     4081 ctgcaccaag agctggctgg tcataagctg taatcagctt ggtacccacg ccccagacat
     4141 caatcttggc cttttgcatc ttgaggttga ggatagtatt ttcgtccaaa tcattagaag
     4201 cataaatctt agcctctgta aatccagcct cgtccagttg ctgacggact ttcttagaaa
     4261 tgtaggcaat atccccagag tcaatccgca cacccataaa gttaatctga tcacccagct
     4321 cacgcgccac ctgaatggca gctggtacac cgatgcgaag ggtgtcatag gtatccacaa
     4381 gaaagacaca atttttgtgg gtcgcagcgt aagccttgaa agcttcatag tcattgccat
     4441 aaacctgtac caaggcatgg gcatgggttc ccaaaacagg aatgtcaaag agcttacccg
     4501 cacgcacgtt gctggttcca ttggcaccac caatcaccgc tgcgcgtgtt ccccagatgg
     4561 ccgcatccat ttcttgagcc cgacgtgtcc caaactccat caagggttca tcttcgataa
     4621 ccgaacgaat acgagctgcc ttcgtcgcca ccaaggtctg gtagttgacg atgttcaaaa
     4681 gagccgtttc gaccaactga cattgggcta gaggtccttc cacctgcaca atcggttcat
     4741 tagcaaaaac caaatcccct tcttgggcag aacgaacggt caactccaac ttgaaattgc
     4801 gaaggtaatc caagaacgcc ccatgataac caagcgactc caaataggct atatcactat
     4861 ctgaaaaacg caagtcttca agatagttca caattctttc caaacctgca aaaaccgcat
     4921 agccgttctt aaaaggctgt tggcggaaat atacctcaaa gaccgccttc ttattgtgaa
     4981 tcccttggtc aaagtaaacc tgcatcatgt taatctggta caagtccgtg tgcaatgtca
     5041 aactatcatc tggatacata cttttcctac ttccttagct agaaacccat gaaaattttc
     5101 aagaactttc atgtattcca ataaattagt actattatat cacattttag ctggattgag
     5161 aaaagagtaa caagctattc tccactctcc aattcatcca tatcttgttc aaattttttc
     5221 tgagcccatt cgccatagct cttaagacca agattgccaa taaagaccca tggaaggtaa
     5281 atgatataag taatgaccca agcagacagg tatttaaaat tcaaaggatt gtgctgataa
     5341 atttctatgt tgaattgata attctgcaac atcaaaagag ccgtaatagc caaggttagg
     5401 aaaaaacaac ccaaaatcgt aaaatgaaaa cgactatagt aggtcactcc cagataacgg
     5461 gcacgattga aaaagtaaaa tgtccctatg atgataacga ttagcagcat attagaatta
     5521 aaaaggcttg gtgctaatac tgaaatgata taagatagga gcgacaaagc aatgcagata
     5581 tagaaacttt cagagcccgc tttattgaac agttgttctt ctctttcgtc tagtaattga
     5641 taataataaa atctattttt catcttcttc ctcccaaaat agttggtcta gggttttccc
     5701 taaacatctg caaatagact ggcagagcga gagactggga ttgtattttc ccgcctctat
     5761 caaaccaata gtctggcgtg tcaccccgac agcctctgcc agttgacctt gtgttaaatc
     5821 acgctctacc cgagctaatt ttaattttaa atttttagcc accttcgtcc tccttatagt
     5881 tttaatactc atctactctt aaaaaatcca aaaccaacac aagctatcag ctatttatta
     5941 taaccccatt aatttgcact ccagtattat cttcagccga aaatcagtat tttaggttgt
     6001 ttgaaataaa cttcctagtt tactctttta tttttattta gtattagctt tagtaggatc
     6061 ttttaaacga gtttttattg cttatatttc ttgtttagtt tagttggttt catatcacta
     6121 ttatataatg cttttggaaa tgagcctagt ataagtcaaa aacgtgttga atagtgaaag
     6181 caggagcata ccaagatgac tgattttttt attgtatttt aggtatgcaa aataatacta
     6241 aatgaaacta aaatgaatac ttcttgcttt tcttgagagt gaaaaagcac aataaaatga
     6301 ttgtagtgat taccacaaga tactgactaa tagacatcgt atttgaagcc acaaatacag
     6361 gtaaagaata aaaaggaaga agttcaattg ctttgataaa caaatcatta ctagtattca
     6421 tcatcatcgt atttaatata ttagggataa agagtagtaa agctactaaa ataccaagcc
     6481 acttttcaat ttgtataaat agaaaatgta agataataga aaataaaaca ggactaacaa
     6541 aattgtattg actacaatag ctactataaa atctaatcct aaatcacctg gaatacccaa
     6601 tttacttact atgactagta acacaatgcc attcaaagca taaataatgg aaactgagat
     6661 ggcatataga aaattagaca agacgtaaat catccgattc ttctgttgat tataaaacaa
     6721 acttaccgta ttgtgggaaa aatctctact aatgactcga ttagcatgta taacagccat
     6781 taacataccg agcatagcat aaaagtttga aatatgctta ataccaagcg atgtcccttg
     6841 agtctttaga ataaagaatg taaccaatat cggcggtata aacgagataa gcaaaccgag
     6901 atatattacg cctgatgaat ataaatttct tatattttcc ttaagaaaat taaatttatt
     6961 taatttcatg attataacct tcctttattt tgaacgattt agataaatat ctttgagcgt
     7021 ctctttttta gtttcaaaat caactacttt aatagagttt tcgttaaaaa atttaaaaag
     7081 ctcactactt tgaatattcc cagacatagt aatgctcagt ccctcttcct gaacaatatc
     7141 cccaaattct tgtttggtaa tgaaaatgtc tctatctgta gctgatgaaa aagctatctc
     7201 aaacaagaaa ttatgactat cttttcctac tttttgaaat gtcaaaagcc cgttctccaa
     7261 gaaaagaacc ctctcacaaa tttcttcaat atcttctaat ttatgactcg atattaaaat
     7321 tcccacattt tcatgtaaag ctaaattttt tagaaccgat aaaactattt gtgatgattc
     7381 aatatctaaa ccattagtcg gttcatctaa aatcaatata tcaggttccg taacgagagt
     7441 tagaagcaaa gctaattttt gttttgtacc caaagaatag gtctttactt ttttattaat
     7501 agactgagtc aaatctaact cttggatcaa acttctaaat ctttcttgat tgtagtcaac
     7561 accatataaa tttgacaaat attttaaatt ctctaaacct gttttagata aaaataattt
     7621 tggttcttcg attaaatacc caacattatc actgcttata atattacctg aagtcggttg
     7681 attattctga acaagaattt tcatcaacgt actcttacca actccatttc tccctacttg
     7741 accaacaatt tcacccttgt taagtgcaaa atttatatct ttgagaatga ttgaatgacc
     7801 ataatgctta cttacattta taacttccat tttgtaattc ctccattaat attctcggtt
     7861 ttctctttga ttctcattaa ttttaaaaag ttgcgcctct ttttaacaac attatatcat
     7921 atatctaact taatgcaata tataaatgtc attttgtaaa attttattaa taaaaaactc
     7981 tctacaacaa aataatagag agttttctgc ttattaattt ttttcaaaat atctaagaca
     8041 tcgcttcttt gtttaatttg ataggctttg atacctaagc tccgacttta tcacttaaaa
     8101 aataaaaaag gacagctaat ctcttgcgca tcaagggatt tcgccattct ttaatctcgt
     8161 ttaagtgttg tatatggagc tttgcataat tttttaacac taaacaacta cattaagcac
     8221 gaactgtgac gctggttcca tcttccttat aaagattgat aagcccctct ttaagagctc
     8281 gaaccatgtc tcctgattga acaggttgtg ggactttaat agtcaatagt tccattggat
     8341 ttggagcgcg gtcgatttta ttgcctttgg catcatgcaa atcttcaata taggtttcaa
     8401 aatgacggaa acctggacca taaaactcaa cttggtcccc ttcgttaatg acatttcgtt
     8461 gacgaatagt tgctgtttgt gccgcatcat cataagaaac cacttcagcg acaaacttgt
     8521 actcaggaat tttacgacga gcaccaaaca actgctcatt ttcagatggt gtaccatagt
     8581 aaaatcctgt agccagttca cgttgggcaa acttccacat ctcgtccacc aagtcttgtt
     8641 tgatagcttc aaacttttca ggactttcaa gataggcatc cacagccgcc ttgtagcagt
     8701 tggttactgt taatacatag tgaatagact ccatacgtcc ttcgattttt agactgtcca
     8761 caccattttc aatcatatct ggaatgtggt caatcataga catgtcaacg gctgacattg
     8821 aaaattcttc tggaatctca ccctgcaaac tcttacgttc tttcccaaat ggcatatcgt
     8881 aaaggtcgta cttccaacgg catgactgag aacatccacc acggttggca tcacgcatac
     8941 tctagacgga ttgttttgac aattctaacc ttttagactt tgcataataa ctgttaaaca
     9001 gtcgaaaatt atcccagttt taacaagtag tcaaaatacc agataaagta aaaagaggct
     9061 aggaaaaaag tctttaaaat cttaaaaacg catagtatca ggtattgaac aatcttgata
     9121 ttatgcgttt tattgtggga agatttactt cattttctct tggaattgag ttttctccta
     9181 cttcaaaact agatgatctg ctatttaaaa tagcgttcct tatgattttg gcaacctgga
     9241 ttaaagcgag aaaaacaaaa gaggcaactt aagctttctt tatattgctt atatgttaat
     9301 agttttagac aaacaccaca taaaataggc ttatcctgta tcaaagataa gggataaggc
     9361 tcaaaagggt gattttctaa tgaatcatga caccgataac aagcataata ctttttacaa
     9421 tcatagcatt gtaaagcaat aatatccagc ttgctatggt aatgaatgca tcttgtttgc
     9481 ttatccacta agaaaccctg tgcctctatc atttcctttt cctttcttaa gctcgaactg
     9541 tgacgctggt tccatcttcc ttataaaaat tgatgagtcc ttcttttaat gcacgaacca
     9601 tgtctccagc ttgaacgggt tgtgggactt taatagtcaa tagttccatt ggatttggag
     9661 cgcggtcgat tttattgcct ttggcatcat gcaaatcttc aatataggtt tcaaaatgac
     9721 ggaaacctgg accataaaac tcaacttggt ccccttcgtt aatgacgttt cgttgacgaa
     9781 tggttgctgt ttgtaccgca tcatcatagg aaaccacttc agcgacaaac ttgtactcag
     9841 gaattttacg gcgagcacca aacaactgct cattttcaga tggtataccg tagtagaaac
     9901 ctgttgccaa ttcacgttgg gcaaccttcc acatctcgtc caccaagtct tgtttgatag
     9961 cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgtag cagttggtta
    10021 ctgttgatac gtagtgaata gacttcatac gtccttcgat ttttagactg tccacaccat
    10081 tttcaatcat atctggaatg ttgtcaatca tagacatgtc aacggctgac attgaaaatt
    10141 cttctggaat ctcaccctgc aaactcttac gttctttccc aaatggcata tcgtaaaggt
    10201 cgtatttcca acggcatgac tgagaacatc caccacggtt ggcatcacgc atactcatgt
    10261 ggtttgaaag agtacaacgt ccagagtatg aaatacacat agctccatgg acaaaggctt
    10321 caatttcaac atctgtacgt ttgcggatct cagctaattc ttccattgaa acctcacgcg
    10381 ctaaaacgac acgagtcaag cctagctctt tccagaactc aagggtttca tagttagtgg
    10441 cactggcttg ggtagaaagg tggatttcaa ggcctggtgc ttcagtcgct gcaatcataa
    10501 tcaaggctgg gtcagatacg ataactgctg caatcccgat atcacgcagt ttacggaacc
    10561 actcaccagc accagcttca tttccttcgt gcataaccat attagccgct acatagacct
    10621 tggcaccata cttggccgca aactgcacgc cttcttccat ctgttcgaaa gtaaagtttc
    10681 ccgcacggct acgaagacca taggcctgac caccgataaa gacagcatct gctccatact
    10741 gaacagctac ctttagcttc tctaaagtcc ctgcaggtga taaaacctca ggacgtttta
    10801 atgtttttgt catgatttct cctatttgca atataaaagt ttgacatttt tccttctcat
    10861 tttatagtaa ataaaggata aaatcaagcc tagacggatt gttttgacaa ttctaatctt
    10921 ttagactttg cataataact gttaaacagt cgaaaattat cccagtttta acaagtagtc
    10981 aaaaagtcta gaaaagtaaa aaccagtatc caaagatact gactcgtaaa aatacataaa
    11041 ttagtcctta gatgactact cccactctgt tgctcctata atggaaaagg attgatacag
    11101 tctagaatat cgctttttta tttattattc tgatataaaa ctgttagaat tgattttttg
    11161 ttttataccc aaatatgaat agagacgtag ctaataagtt gaataacata tttggaaaaa
    11221 tgagaaatag caatattact agaactttta gaaacaatca atatttaaaa agaaaaaagc
    11281 tcaaagaatt tattaaacca tgttataata gatatagcta taattttatt tataacaaga
    11341 ggatagaaat gaccgaatta gaaagaaaaa atcgaaaaat tagctaagaa atattctgat
    11401 aacttaaaca tcaaagttca agagagagtt cgtgaaatgg caaatgataa taagagccat
    11461 tatttgatat acagagtttt aggtatttca tttgaagaag gagaaaatat cgatttgtat
    11521 caaaataaag gtcgtttttt atacaaatat gctggttcat ttttagaaga agctgcagta
    11581 ctatgcttta acgaaaaatt tggtacagaa aatacttaaa aagttaacat tcctaattct
    11641 gaaagtacaa aacctaagac ttttgaaatt gattgtttag tcggagaaaa acacgcatac
    11701 gaaataaaat ggtgggatgc aactacagat ggagaccata taactaaaga acacactaga
    11761 ataaaagtta ttcataacaa aggatatata ccaattcggt taatgttcta ctatccaaat
    11821 agaactcaag ctataaaaat tcagcaaact ttagaaacat tgtataacgg tattggaggg
    11881 aaatattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    11941 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    12001 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    12061 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    12121 attcaatcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    12181 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    12241 ttgcagatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    12301 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    12361 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    12421 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    12481 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    12541 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    12601 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    12661 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    12721 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    12781 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    12841 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    12901 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    12961 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    13021 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    13081 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    13141 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    13201 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    13261 cactcaatta acaatttcat aggtttagtg ccagaaaacc ttgatttatt aaggtttaca
    13321 atgcctttta aatatatttg gcgggatttc tggcggggtt atctttttag gttttgattc
    13381 ccgttgaatt gaatttttgt ttttggagct gtatgtatgg atatattccc actcattatt
    13441 tcagcaatag attcgtcagc tccgcgccaa aggtgtgagt aatgtttcaa agtaatttct
    13501 gggctagaat gacctaacct tttcgacaaa attaagacag atacattaaa ctcgtttatc
    13561 aaataagaag cgttactatg acgaagtcct ttaccctgta ttcgctttac attagctagt
    13621 tcagaatatc gttgaataat tctagctagt gtagatttta tcattggaag gctatcatat
    13681 gtaaatataa aatcagtttc attgcctaaa ccaatttctt tctgtctgtc tttccaacgc
    13741 tttaaaatag aaatcgtatc atcatctagg gaaataatac gtttgccatc acttgttttg
    13801 gtataggcat ttctttgcca gtttttcctt gattttagaa taagcatatg atgaacacgc
    13861 atacgctttt tatcaaaatc aatatcattc caccaaagtg ccattccttc atttactcga
    13921 atacctgtca tgaaaaaagt ccaaagcata acgaaattaa gatgttcata aaaatcatca
    13981 agacagattt gagcaataac acgctcaaat tctactttag tccagtatgg aacgatagcc
    14041 tttcctttcg gaatagcttt ggctttctta gagatattag tttccaaata acccatttct
    14101 acagcataat caagagactt tctaaacata ccaaagatta gactagcgta ggcttgagag
    14161 tagccagaac cgttttcgtc tttgcttgac agtaaccata tccgatagtt ttgaatatct
    14221 tcaatagtca aaccacgtag tgtcttgtta taaaatcgtt cagcaatctt ttcaagattt
    14281 ttgattctga cagcataagt actttcttcc acatacgatt tataatatgg tatataacaa
    14341 tctaaaataa actgcttgac agtcatattg taattagcgt aagtatgagc tttgtgatac
    14401 tctcgtttta cccgagtcaa ttctaaatac gcctctctgg cagtagaaaa aggcttaccg
    14461 ttgctatctt ttctactttt ctttctaata cgtttaccac tgattctatc aatgcctagc
    14521 tctgtttcat agaaatattt tcctttcgta tcaacaaaca caccgctata acgtgttttt
    14581 gccatttgtt attcctcatc tagttttaca ccgataaggt tttctaccct ttcccgtggg
    14641 actagtccaa gtctacggtt attgtagaat ggtatacctt tattatacac caaatcctgc
    14701 tttaccgctt gaataatact aattgcagta tgtttcttat atcctagttt tatcaagtcg
    14761 tctttactaa tcaatggttt catacgctta ctattccttt ctgattttta ttcttgtatc
    14821 agttgaattt tgaataatct cctcattgtc atctattgat agattgtaaa tcgcaatatc
    14881 ttctttgtac tcaagattat ctaaatgacc tactgaaaaa ctgggggtta atccctcaaa
    14941 ataatttctt tctaaatttt catagcttac tatcggtttt attaaaccac gagatgaaaa
    15001 atattttggc tgtttatatc cacttggaat agctagtaaa tcttttgtga tatattttgt
    15061 aatgtagtta gcaacttttt cagaagaatc gatttttgta acagtactaa atcctaattg
    15121 atatgaatca acattataga cttgcttgcc attcttattt atcaatcgac cagttttagt
    15181 atttcttgct tttgttaatt ttggactaaa accgcctgtt actccatgaa aatgaagccg
    15241 tccattttta tgtaattctg gtatgaaaat gtagtgaaat tttccatatt tttcacgctg
    15301 agctttgagc caagtgcgta ttttcttttt tacgattaaa taatcatggg aattgatttt
    15361 ttcgtcgtta aaagttaatg tccaaaataa atcgaaatca ttgcacagca tgtagtgacg
    15421 aatacgcctt tttatcctat tggcttgctg atagagttct ttttcacttg gacttttaga
    15481 agtattagat actgtagtat cggtttctcc tagtcttcta aattttgctt ttcgatagta
    15541 tatgacctcg aaagtatttg aattatattg aattattttt gtgttatata attctctagt
    15601 cattagtcct ccgcttatca tgcctgcatg tcaagtagca ggctaatata cacatctagc
    15661 gagtcctggc ttgcttatga gcaagccggc tcactagata gttagttcat tctatctgct
    15721 ttcttggaat agtttgaaag tcccttattt tatttttgaa atctattgaa tctaaatcaa
    15781 aatacggagt ctcaaaatat tttattccgt ttgttttagg agttaaaata tatccttttc
    15841 caactcctcc tctgtactcc gccaaaagat ctattttctc tttacccatg acactgtaaa
    15901 acgtttcttc agatatactg gaactattcc ctaaaataat tctagtttgg cactgctctg
    15961 tgactgcacg cggtaaatca gaagcaagga gcttttggct tgcaagaaca agcaatccct
    16021 gtccagaagc ccgtgatttt aaggcaagta tttttagtag cctaaccatt tctttttgtt
    16081 gcgctgatgt tccacattcc aaagctgcca gcacttcatc aaaaattaaa taatgtgcag
    16141 gtaaagaaaa atgtttgtac gtggtcccaa aatcaactga agaaaatgcg aaatatcgct
    16201 tatatctatc ttccatttca aataccattt gttctagaag tagaataatc tcttccgcat
    16261 tacgtgcgac aggaatacct agattttcaa atgtcgcacc taaagaggtt tgtttagcgt
    16321 caattaaact tatagaatga ccttgtttaa ttagtaaccc agctagtgtg gctagataaa
    16381 gtgacttccc agcaccacta ggagctatta taatctgctg attagcctca ctagctatat
    16441 caaaacaaat attatcataa agttttattg gcttataatt gatataataa tcttcatctg
    16501 ttatcttgaa tagttcacta acagtatatc ttggatttga ttttccatat tttataacaa
    16561 cgtaactatt ttgcacagtt gattccaaga tattccagtc ctcgttagta gcttgaataa
    16621 gaaattcggt caaccgcctt gttatttctt ttacttgctg aatattagga attgtccctg
    16681 aaggattgag ttcaattata atcctttcat tttctttata aaatttccat tcaactgttt
    16741 ttatctgtat tttattagag ggaagttgaa ttaggtctaa acgttctgtt gcaagtctaa
    16801 gaatgcttaa aaatctgtac ttccatatag gagagtaagt agaaaataag aattttacta
    16861 caatatacca tataaaaata tctaacagaa cagaagatat aacaatactt atcttgtaga
    16921 tagtgcttaa taaaggaaaa tgtgatgaaa gaaaggtaat gataacagat attaggaaca
    16981 cctttaacag tttcttaata agagagtact gcctttcttt acggctttct atagtttctg
    17041 aaacagataa gtaagtaggg gtatattcac gacaatcata tttactaagt ttccttttta
    17101 ttttagatac tatcatgatt tagcacccga taactttatt tctgaaataa tgagcttgaa
    17161 ttctcggtac gcaccaccat ttcgaccatc agatacccat tttaacgcta ataatgctcc
    17221 ttctaaatct attgttttag caatgattaa ctcattatta atttttttta aaaaagattc
    17281 atcgttgtat atctcaatag tgaaaggttt tatgctactt aaatctccac caacctcttg
    17341 aatagcctta acaatttctg actgaagagc caataaaact tttttactta ttgttccatc
    17401 aatgacttca tttttttcat tacgtttagg aacatctcta cattcaataa caaaagcact
    17461 agtaggagta tgttctacat tggacgtacc aattagtaga tttttcaagc ttggtgagtt
    17521 aaaactcact tttccaaaat tattttccat ttgttacctc tttatctttg tgtgcacact
    17581 agattaattt catcaagcag ttcatgacct ccttgacagt catattgtct catttttaat
    17641 tagttgaaat gtggggataa aaattttttg acaacaaaaa aatccccacg cgaagtgggg
    17701 aaaatatgct atacagtact aaataaaaat tttattattt acgataaatt aaactttcga
    17761 gtgttagttt atctatcatt ggtaataaaa tatactttgc taataagtct aacttttctg
    17821 gaagtttttg atagctaaga taagattcct tatttttagg tgatagtgtg acagagtcct
    17881 ttttcctaaa taaaaatact gaatcgtttt ctaaaatttc tatagtatca aactgattat
    17941 aggtaaaatc aataaattta tcttttaatt cattgtaaga agaacttgcc aaaggaaaat
    18001 gttgttgaaa gtattctttg atatctcctg tatttgttag tgataaattc aataagtgct
    18061 tagaatattc tggtattcct tgaatatcaa gaatcatttc aataaagaaa tcttctaaat
    18121 attcgtctat atcacggccc cataatactt cattctcatc attaaaataa tgttcttcat
    18181 taacaaagta attcaataca cttggagtta ttaaataggg attgttccta cttaaatcag
    18241 ataaattgga gtaatttaat attttcccaa taagtttttc atctgaatgt aaatcgatat
    18301 gtcttttgag ttttaaatct ttgtatttct tttggattct ttgtgaacat tttttaaaaa
    18361 taaaatgaca tgaattagga aatttttgct tacataaatt attgaattgc ttacttgaca
    18421 tatatttaaa cttcttctat atcatctgga atataagtaa ttacatcata tacattgcag
    18481 ttcaaaataa aacatagggt atctaatgta gctgtagtta ttggttttcc ttttttcatt
    18541 ctatgtagtg tattgctgga tagaccgtgg tgaaaaatta attcgtactc tgtttttcct
    18601 tgtttaaaca aggtttcgta gaagggttta tatgaaatca tcgttctcat ctcttttcta
    18661 aatagataat ttcattttat ctctattaat ttgttgacta tactcaataa attgactata
    18721 attagaggga gagtaattga ttggaggatt ttatattgaa acttgaagat tttcagactt
    18781 ttccatttaa aagtgtccaa gaatatattt cagacaaaga aaaagcaata aaattcagtt
    18841 tcttattgca aggagacgaa cctgaccgtt ctgaattgat gaaattaata tataaagaca
    18901 ttttcgaatg gtatgatgac aaagtacata gtggcgacac tcttataaca tatcgtacag
    18961 caatttttcg aaaatattat ggaaaatcat atagtaagtt atccagagat aagcaacgcg
    19021 agattcttaa tattataaaa tcatacactg aatatgatga tgattttcct ttcgaatttg
    19081 agcttgacaa taaagaaaaa aacgtttatc agatttgtaa taattatcaa ataggaaatt
    19141 ttggaatttt tccaaaagga agaataaatc ctaaaagagc acagtctcct tataatgatt
    19201 attttgacct tactctatca gtaatatggg acttatatga tggcacattg actccagatg
    19261 atgagtttaa aagagcaatt ttagatgaaa aggaatattt tgaccaattt aaagattttg
    19321 aaacatttct atccgataac ttcttaactg tattttttga tgatgaagga tatttaattc
    19381 gattatctga aattgatgat tttgaggaat atgtaagaat tagtaatcaa attatttata
    19441 ctagagggct tgctattcta acctaccttc aatcaatgta tgatgataat agtgaattgc
    19501 ctacccaaca acttgaagaa aagaaaacag ttcctagacc aactaccaaa gagttagcac
    19561 atcgaactct taaaattgca gaagaagaaa tagataaaat ttctaaattt gatgaatatt
    19621 ataatgaact tgaatttaat cttcataaag aaaaatttga aactacaaaa aaacgaatat
    19681 acggtgctat tgttcttttc ttgttcattg tatcactatt tttttacact tcagaaatta
    19741 tcatgttcat ttggatttta tctacagtac tatatgtagc agataaaatc agaattgtta
    19801 aagaaaaaat aaaatacgat aaaataataa atgcgactca agaaaaatat agggaagaaa
    19861 agaaaaaatt attatctact ttgcgaaaag agtactactc cattccaact gaatttagaa
    19921 catataatca tatttcaggt atacaatatt ttttaaacgc tgatattgca tcaaatttgc
    19981 aacaagctat tcactattat tcaaatgaat acaattctaa aagaatgcaa gaccaaattt
    20041 atagcttaca tcattcaaac acaatattac aagatagaat taaggagctc gaattagaaa
    20101 gagagctgga aaaatactaa tcaaaaagga gaatactaca atgacaaaat ttaatttaca
    20161 atcaaatcaa atttatagtg aattaagtaa gtttgagata gaagaaatac tgtataatgc
    20221 tacaaaacaa ttgaacggta gtgttgaacg gcaaagttct gaagaaattt catactctgg
    20281 acagggaaat ttttttgatt acatgaagca cccaggttta agtagatata catgttggca
    20341 agtcttagtt actatatcag atttagggga taaacgaaaa gttgagctaa ctgcagtcgg
    20401 agaaagtccg attagttacc tactaaataa ttttctatca ttcattactt tttatacctt
    20461 attccaacgt catcgtaatc ttaattttgg catatcaaaa gaaaaggcta aatacctttc
    20521 taatttgttg tagaagataa tttatataca aaaaactctc ttagtacata ttcacactaa
    20581 gagagttttt tgtaatctat ttgccaagtt tggcgggaaa attggcgggg taacttttct
    20641 aaaaagataa atttatacca ttctaacttc tataaacccg atagaatcgg tgtaaaacat
    20701 tcatttttac tttctatatt attcccactc aactgttgca ggtggtttac ttgtaatatc
    20761 gtagacgata cggttaacat gatccacttc atttacgata cgtacagaga ttttttgaag
    20821 gacttcccaa ggaattttgg caaagtcagc tgtcatacca tcgatagaag tgatagcacg
    20881 gattgcaatc gtgtagtcat acgtacgacc gtcacccata acaccaactg aacgaacgcc
    20941 tgtgttaaca gtgaagtatt gccagatatc acggtcaaga cctgctttag caatttcttc
    21001 acgaagaata gcatctgact cacgaactgt ttcaagtttt tcttcagtta tttcacccat
    21061 gacacggatc gcaagacctg gtcctgggaa tggttggcgc catacgatat ggtctggcat
    21121 accaagctct gtaccaagga cacgaacttc gtctttataa agagtattga gtggttcaat
    21181 caattcaaac tgcatgtctt ctggaagacc acccacgttg tggtgtgact tgatagtttg
    21241 agctgtatcc gtaccagact cgatcacgtc ggtatataag gtaccttgag caaggaattt
    21301 cacatctttg agcttgcttg cttcgtcatc aaatacatag acaaactcgt taccgataat
    21361 tttacgtttt tgttcagggt cagaaacacc tgcaagttta tcaaggaaac gcttagctgc
    21421 atctgctttg acgatattca aaccaaactt accaccaagc atgtccataa cttggtctgc
    21481 ttccccttta cgaagaagac cgtggtcaac gaagatacag attaattgat ctccaattgc
    21541 tttttggaga agaactccaa caactgagga gtcaacaccg cctgatagac caagaaggac
    21601 acgtttatca ccgacggttt cacgaatttt ttggatctgc atatcgatga agttatccat
    21661 tgaccagtcg cctttagctt tacagatgtt aagggcaaag ttacgaagaa tatcatttcc
    21721 gtatacagaa tgacgaactt ctggatggaa ttggataccg taaatatgtt tatcagggtt
    21781 ttcaatggct gcgtatgggc agtcagcgga tgtacctgta cgaacaaagt cagaaggaat
    21841 ttcagtaact gcatcaccat ggctcatcaa tacagtttgt tcatcaggtg ttgattcaaa
    21901 aagagctgat ggtgtatgtg ttagggttga ttgaccgtat tcacgatttc cagcatcacc
    21961 tgcaggaaca acttttcctc caagcttatg ggtcaataac tgcataccgt aacaaattcc
    22021 caaaatagga attccgagtt cgaagatttc tgggtcaata tcaaatgaac catcttcata
    22081 tacagaattt ggaccacctg aaaggatgat tcctacagga ttgatttcac gaacttcagc
    22141 agctgaaatt ttatggcttt ttagttctga aaaaacacca atctcacgga tacggcgtga
    22201 aatcagctgg ttgtactggc taccatagtc caatacgatg attttttcta catcttgcaa
    22261 atcagttgaa atgttgctca tctttttcct ttctcaaaag aaatatcttt tctcaatatt
    22321 ctatcacaaa taagggcgaa ttaccaacta aacaaggcga agtttgactt tttctagttt
    22381 attggggtac aatagagaaa agatagaaat gaagtgaaaa atatgctacc tgcttatatg
    22441 aaaatccatg atcagataaa aaaggatatt gacgagcacc gttgggctat tggtgagagg
    22501 cttcccagtg aaagagattt agctgagcag tttgcggtca gtcgcatgac cctccgccaa
    22561 gccgtatctc tattagtcga agaaggcgtc ttagagcgcc gtgtaggaag cggcaccttt
    22621 gtttccagta ctcgagtaca agaaaagatg cgagggacaa ccagttttac tgaaattgtc
    22681 aaatcccaag gtaaagttcc ctctagccag ctcatttcct acaaaaaaac cattcccaat
    22741 gagcaagaag ttgccaagct aggaattttt ccaacggaca atattatccg aatggagcgg
    22801 gtccgctatg ccgaccaagt tcccctagtt tatgaagttg cttctattcc tgaaaaattc
    22861 attaaggact ttaaaaaaga agaaatcacc agtcatttct tccaaacctt gcaaaaacat
    22921 ggctatcgta tcggcaaatc tcaacagacc atctatgctc gccttgctaa agaaaagatt
    22981 gcccactatt tggaagttga aaaaggacat gctattcttg gattgactca ggtttcctac
    23041 ctagaagatg gtactgcttt tgaatacgta aaaagtcaat atgtaggcga acgctttgaa
    23101 ttttatcttg aaaataatta gattaccacg caaaaactct ctgtcacgga caaagagtct
    23161 tttttatttt tctaagaata aatctttcaa aggaatcaaa gttacagcaa acaatatcat
    23221 tgccatacca agaaaatcaa tgggataaaa ttgttcattc attattaaga aggcaaagaa
    23281 aaccgccgat attggctcaa ttgaagccaa caagcttgac ttgaccggtc ctatcagact
    23341 ggctccttta aggaaagctg tataggcaaa gacagtcccg ataaggataa tgcctgcaaa
    23401 cgcaaggaga aaatcaagac tagttgggat atcggcctgt agaacccctg taaaaggaag
    23461 ggcgaccaaa cctgctatga ccattcccac accaatgacc aagctgctcc cccacttttt
    23521 aatcaaggct atgggtaaaa tgatatacag agcataagtc aaggcagaaa agagacccca
    23581 gaacaggcca gcaggtgtca tggataactg gtccaactgc ccatgtgttg cgatcaggaa
    23641 ggttcctccg atggcgaata tgatggaaac tatctctccc agtgtcggtg ccaccctatc
    23701 cttgatacag ctataaatta aaattccgac aggacaaaca tactgaagca ccgtcgctgt
    23761 tcccgcattg gtctcctgaa tagcagacag ataggcgaat tggttgagaa aaagaccaat
    23821 cagagcaaaa ataagaagag acagcaaact ctttctatcc tttaaaaaga ccagtatttt
    23881 atcctttgca gtagcataag ccaagatcat gagaattcca ccagcgatta aaagacgcaa
    23941 gttggtcaag accagagccg aaattccgtg tgccattagg tattggccac tcgttcctga
    24001 caacccccaa gcaataccag ccacaactgt tagtaaagtc ccttttaaac tatttgacat
    24061 gtctctcctt actcttcttt acgaatcaag ttcatcactt gattgcggtc taatatccat
    24121 tgagctctct cgtccttttc ataggtacga ttcgatagga aaatagtggc ttcttgcttc
    24181 tgacgattcc acatgataaa ggtacctgta tagcccgtat ggtctagcca atctccttcc
    24241 aaattccatg ctaaagaacg ttccttgtca tccaaaggag aaaaattttg atttaagtct
    24301 cttgcaaaat catctgctaa atagtgttct aaaaagattt gtaaatcctt tatagtcgaa
    24361 aataaaccag cactcccagc atgtctaccc aggagacgag ccttgggatc atgcactatg
    24421 cctgcctcta cacctctaac tgttggaaca gcaagctcaa ctggcccaac cttggtttcc
    24481 gtcattcccc aaggtttcca gacttgatcc tttaaaatca catccaaatc ttgattaaaa
    24541 attctttcca aaataaagcc caacagcaaa aaatggacat ccgaataaag aaaggctggc
    24601 tgacttcgtc tattgagatg aaacatcgct tcctttaatt caggggctgt taaaagatca
    24661 cgattaggaa taaaaggatc aaggtctgtt gcatgagtca agagctggcg aatagtgatg
    24721 tctggataat cactctcagg taaaaaatct attaccagtc tatcaatatc taattgacct
    24781 atttcccaca agaaggtaca aactgtgcca accccaacaa ccttactgac actagctagg
    24841 tcataaacta gtcctgcctc agtctgcaag ccatgctctg ggtcactctg gcctaaatag
    24901 aactctgtcc attgattgtc cttaaaatac gcaaaagagg ctccgggata aattcctgcc
    24961 tcgatttgtt cttctatttt tttaataatc ttggtccact tcatacttct tcaaaccaca
    25021 attcaacatt atttctatct ttacaaagga agaatttttc agacttagga ataaaatatt
    25081 cagtagactc aaacttctgg cgaagacttg ctatgtctaa ttcattgacc aagaacttga
    25141 gcatagataa gtcccaggta accgtattgt ccacagtcaa atcctgcccc tgagctggaa
    25201 taaaatcaag ggatgcccca atttcagatg attccaagaa actttcgata tcagttggga
    25261 gatgtaattc catagaaatc tcaaatttac ttaaagaaat tgataccaaa tctgtttgaa
    25321 attcaggctt ttctcctact tctactagac ttgctctgtc atcttccgca tgaatcaaaa
    25381 tcaaatcatc ttctggtgag aaaatttcaa aagcgtagcc attttgacct ttatataatc
    25441 gatgaatcga atctgtttta gataagattc cttcaatttc taagggattt tccaccttga
    25501 caatcaatct agctagtttt tttcttccct ctaccttacg agtacgcata ctgggagctt
    25561 cttctaaaac cagcttttca agacccgttt ggtcacctag tgacagaaag gccgattctt
    25621 ctagcaaggc cttcattcca agggtttcaa tataaaatgt ttcatttaat tttctattat
    25681 tagcttttaa agtaggaata atccgtacaa tctgatttac attcataaat tcctccgtca
    25741 ctttttattt taaaggattt tagaattttt tacaagatat tatgctcaaa tttaacatta
    25801 tttagctatt tagtaaagat agtctttcaa ggcttttgac aaagcctgat aaccagcaat
    25861 actgaggtgc agtccatcag ttgtatattc ttttttgagt tggcctgctt ggtctgtcaa
    25921 acaatcaaat actggcacaa attccatctg catataggca gatgcaagct cttgataggc
    25981 ttgattccaa ttctgaattt tttcattcga gcggatatag actgcctgct ggtacttctc
    26041 tccctcattg acaggcaaaa tggaaagcaa tttaatctct gtcaatggat aatcgcgagc
    26101 aacggattga atgatagctt cgagattatt gagagcctca ttcacaggaa catcctttcc
    26161 gatatcattt gtcccaatca gaagaaaaat tttatctact gctccaccat gtagatgagc
    26221 atcaaggttc tctagtaaca gtcctgtctg atagccacga attcctcgat tgacaatcgt
    26281 ctttgaagtc ccaaatagct cctgtagagg ataatactcg acaatggaat ccccaataaa
    26341 aagaatgttt ggttctacaa cagaaatgtg atttaggtga cgatacttgg tttgaatttt
    26401 ttcttgttcc tttaggagcc aattttctaa taactgtact gccacttcat tctccttttt
    26461 ctaaccagtt ttccaagact tgataaactc ctccttggct gttggctggt gctagagcag
    26521 tcgccacagc tttggctttc tcatcagcat tttccatcgc ataggcaatt ccagccattt
    26581 caagcatttc aacatcattt tcactatcac caaaagccat gatttcttgg gatttcaagt
    26641 cccagcgctt gagtaattcc tccaagcccc atgctttatg aatcccagct tggaggatat
    26701 caatgcaacc atagccactg gatacagctc ggacacggcc atcaaagaga gcattgattt
    26761 cttccaaaac cgaactcaaa cgttcctcac caacaaccat gctcatcttg agcacaccac
    26821 caaagaggtc agatgttaat tcatccacaa attgcatccg tttgtagaat ttttcaatca
    26881 tttctggagt cataaaactt tcaagatctg taaaaatcgt accttccttg acaaaatcac
    26941 ccttcatccc cgttacaaca aactggtcct gacacgctcg acccttgaaa tgagccaaag
    27001 ccttgttgac aatggcgtca tcccatgtct tagcctgaat caattcattg ttttcaaaaa
    27061 tacgagcgcc attagcaaca accagaacca ctcgatccac caagggactc agtagttgtc
    27121 tcatgcggtg aatttcattg cccgtcgcaa tgacaaaacg aatgcccctt tgatccaact
    27181 gatctaaaat cttttccaat cgtgggagat caagctgacc tctagcatcc agcaaggtcc
    27241 catccatatc tgtcgcaatt accttaatca tcatttactt tcctctggat tcaagctaat
    27301 accacttcaa tcccacatgt tcattcattt ctttataggc tgtatcaatt cgttccttag
    27361 tcgcttcatc taactggtca cgatgactgc caccctctat aaaatcttcc aaaatataag
    27421 tttggtaatg atacaaggga tatccttctg gtgaaaaggt tccctttggt gttcgattga
    27481 cccaagtagg atgagcttta gctgttccga tagttgtttt tacatccttc ttcttgatgg
    27541 tgacatccat gagaacacca cgttcagtcc acttagcatt ctcttcatct cccatagatt
    27601 caattcgttg attggaaatg aagttcccca ttgaatagat aatgagcttc ttatctccat
    27661 ctttttcaac cgtttcagat ggttcaacaa cgtgaggatg ccctccaaag ataatatccg
    27721 ctccccaatc gatcatcttg tgataaagag ctttttgttc ttcagttggt tccaatcgat
    27781 actcaacacc catctgaggc atgataatgg tgatatctgc ttccttctct gcccgttcaa
    27841 cttcagcctt tatcttatct tctcttcgtt taaatctgaa agataacgat tatagtcttc
    27901 ctgagaaata tactgctcaa ttccattgaa accataggaa taggctaaca atgcaacctt
    27961 gataccattc acttccttaa tgaccagcgg agcctgatca cgtggttcgt gcgtataaac
    28021 tccgattgga atgattccag ctttctcaat aatatcggcc gttgaaataa ctccctcaat
    28081 ttgcgaatcc aaaatatgat tatgagctaa atccagcaca tgataacctg cctccttaat
    28141 agcatccata acttcagcag gagcattaaa gagaggataa cccgctaaat aatgatcctt
    28201 attaatggtt ccttcaaaat caccaatagc taaatctgct tgcttgagcc aaggagtcac
    28261 atactcaaaa ttttcatgaa agtcataggt accgtcttct tttttagctg aaaagaaaag
    28321 tccatcgtgg tagagcaaat ccccgtgtgc cataattctg gcagtttttt cctcttccta
    28381 ctcctgagac ttttgcttag tcccctcttg agaaatagta tctcgttttt gactagtcaa
    28441 gggattcctt ggaagctttc aaacaacaag accaagccca ttgataaacc aactgctagc
    28501 aagagtatcg ccacaaatcc cttattgctc caattgcgat aactcctaaa aagtttacca
    28561 agcccttcat aaaacgaaaa gctaaaccac cctgatttcg attttgtctt ctttgcatct
    28621 tcattctccc tactttctta tgcaagcctt ttctttttat tatatcacag ataagtattt
    28681 ctttcacaat tgaattgaac ttcctatcta ttttctataa atcctaaatg ccataatgct
    28741 ttcaatcctt gtcattttgt gatatcatgt agaggtaatg aaaggaaatg aactaatcca
    28801 cagtggctta ttccaagtat accacttggg ctttggcagt agctaactgc actaaacata
    28861 atataaggag agaaaatgtc tgcaatagaa cgtattacaa aagctgctca cttaattgat
    28921 atgaacgata ttatccgtga agggaatcct actctacgcg cgattgctga ggaagtcact
    28981 ttccccctat ctgaccagga aatcatccta ggcgaaaaga tgatgcaatt ccttaaacat
    29041 tcccaagatc ctgtcatggc tgaaaaaatg ggactccgcg gtggtgttgg actggctgct
    29101 ccccagttag atatctcaaa acgcattatc gctgttttgg tacctaatat tgttgaagaa
    29161 ggcgaaactc cacaggaagc ctacgatttg gaagccatta tgtacaatcc aaaaatcgtc
    29221 tctcactctg ttcaagatgc tgctcttggc gaaggagaag gttgcctgtc tgttgaccgt
    29281 aacgtgcctg gctatgttgt tcgccatgcc cgcgttactg ttgactactt tgacaaagat
    29341 ggagaaaaac accgtatcaa actcaaaggc tacaactcca ttgttgttca gcatgaaatt
    29401 gaccacatta acggtatcat gttttacgat cgcatcaatg aaaaagaccc atttgcagtt
    29461 aaagatggtt tactgattct tgaataaaga aaatcccgtt gcaaagacgg ggttttgtgt
    29521 tataatagag gcatgaaaac aaatgatatt gtctatggcg tccacgccgt taccgaagcc
    29581 ctccttgcaa atacaggaaa caaactctac ctccaagaag atctccgagg taagaatctt
    29641 gagaaagtca aggaactagc tacagaaaag aaggtgtcca tttcttggat atcaaaaaaa
    29701 tctctctctg agatgactga aggtcctgtt catcaaggtt ttgttctacg agtgtctgaa
    29761 tttgcctata gcgagctaga ttgcatcctt gcaaaaacac gccaagaaga aaatccactt
    29821 ctattgattc tagatggtct aaccgatccc cataatctgg gttctatctt gcgaacagcc
    29881 gatgcgacca atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct
    29941 gtcgttgcca aaacagccac aggtgctatt gaacacgttc caattgcccg agtgaccaac
    30001 ctcagtcaaa ccttagataa actcaaggat gaaggcttct ggacctttgg aacggatatg
    30061 aacggtactc cttgccacaa gtggaataca aaagggaaaa tcgccctcat cattggaaat
    30121 gaaggaaaag gtatctctag caacataaaa aaacaggtcg atgagatgat taccattccg
    30181 atgaatggac atgttcaaag cctcaatgcc agtgttgctg cggcaattct catgtacgaa
    30241 gttttccgaa atagactata aaaaagtttc cagtcatctg attggaaact tttttatgat
    30301 taactatgtt ctgtaatgaa tttataggct tcttgaccag cgatagctcc atctccaacc
    30361 gctgttgtta cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg
    30421 actgcagttt tcatgtggtt atccgtcaca atccatcctg cctgatcttg gatattcaat
    30481 tctttaacaa aatcgctaag agggtccaat ccaacataga taaagacacc accgaaggct
    30541 tgttctgtca cttgacctgt tttcacattt tcaaatacga ctgattctac tcggttttca
    30601 cccttgattt cccttactac agaatcccag ataaagctga ttttttcatt cgcaaaggcg
    30661 cgatcttgta aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc
    30721 ttagcaaaac gagtcaagaa gagtgcttct tcaacagctg aatctccacc accaactacc
    30781 aataaatctt ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga
    30841 ctgttcagtt cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg
    30901 ataacggtac gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg
    30961 tcttcgacat tttcaacata accataaatg tgctcaacac caagattttc aagtggttca
    31021 aacatctttt cagccaattc aggtccacta atattagcgt atcctgggta attttcgata
    31081 tcagatgtat tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga
    31141 ttgcttcgag cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata
    31201 gtatcgtaca tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt
    31261 gtcaatcacg caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata
    31321 atactgggac aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagcct
    31381 tggctgtctt atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca
    31441 gaacaaggat ggtggtcaag atcaaactct cgaaatataa agaaaatagt tgcagtagca
    31501 tgatttctct catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt
    31561 tttcctttat ctattatatc aaatataagt ccgtttgtaa ctagcgaaga attcttttgt
    31621 ccgctcttct ttaggggtgt ggataatctc atccggtgtt ccagactcga tgattttccc
    31681 cttatctaag aagagaatct tatcagccac ttgggctaca aaggacatgt catgactaac
    31741 caaaatcatg gtttgacctg acttagcagc atctgcaata gacttttcta cttcaccaac
    31801 caattctggg tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc
    31861 aagcgcacgc gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg
    31921 gttttcacgg tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc
    31981 ttggtcagat aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg
    32041 gcgttcaaac aaattaaact gttggaaaac catagacaac ttacgacgta gggcaaggat
    32101 ttcttcttga gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact
    32161 gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga
    32221 accaatcaag gctacaactt cccctttttg aatatccaag tccagatgat ccaagacagt
    32281 ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc
    32341 acatctgttt gcactgtatc aggtgcagaa atatccattt ttctctcgat gaaacgaccg
    32401 aggctttcaa ttccgatatt gaccacccaa taaacaaggg caacggagat gaagcgttca
    32461 aaatagcgat aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc
    32521 gcactaaaag ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga
    32581 gtagctacca ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata
    32641 cccagactgc gtgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg
    32701 gtttcactag cataagctgc ctcattaaag gcaaaggcga caatcgcaaa agctgcagct
    32761 ggaatcgcat tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa
    32821 gggattccgt agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta
    32881 acaaagaagg cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa
    32941 agaagcgcca aaaccaagcc aaaaagggca ccaccaattg tcaacataat tgttgttgga
    33001 agttgttgga caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca
    33061 tccggaatca attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc
    33121 ataaaaacat cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt
    33181 atttgctacg gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg
    33241 gaagttatat attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc
    33301 ataagatttt cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt
    33361 taacaacata ccgtcacttg ctagcaactc agccgcttct cggtttgaca aacttcctac
    33421 cttatctttt agccctaatt cacggtattt gataccactg gtgttgaaaa attgcttcaa
    33481 ttcaaatcct gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac
    33541 gatatggacg gctttatagt ccacacctaa ttgatttaat tcttgttttg cttttttaca
    33601 agttgaacat ttggggtatt cgataaattc taacatgtgc ttctccttct attgtttcta
    33661 tctttaaaat ctactccttc atgctccaag agccaagctt tcttttccac tcctgcagca
    33721 taacctgtca gacgcttgcc tgctcccaac acacgatgac aaggtactag gatagaccaa
    33781 ggattgcgtc ccactgctcc accaattgct tgagcagaag ccacttgcag gtcttgagca
    33841 atttgtccat aggtcactgt ctgaccataa ggaatgccct gtaaatagtc ccaaactctc
    33901 ttttcaaaat tcgttccgat tggcgccaag agcaagttgg ataaatcctg aggctcgcct
    33961 ttaaagtaat catctaagca agcaataact gggtctaaaa taggatgact aacaacttct
    34021 tctatcgttt catctcctag tcccctctca aaatgcttct gctcctgaac ccaaattcca
    34081 tacaaataat ggtcatcagc tacaagtgat agaataccaa ttggtgagga gtagagtatt
    34141 tttacatact tcttttgcat tatttcttta atttttgata ggccaagcgt tcgccatcta
    34201 ctggcacctt accaacttgt ttaaaaccaa gtttttcaaa aatatgttgc ataaccttgt
    34261 tttcagcatg cgtatctgag cgaaaatcaa gataatcaaa accttcaatc aagccctcta
    34321 agaaggtttg agcaactcct tttccctgca catctgctgc cacagcaata cggtgaaaga
    34381 ctagatactc tgactctcca gcttgccagt ttccctcata aatagcttca taggcctcct
    34441 ctggactctt ggtcacagca gcataggcta gcagttctcc ctcttccaag gctacgtagg
    34501 cttgccctga gatgatatca tcgataataa catctgcatt tggatagcca ttttgccact
    34561 ggtcactacc agcatctgct aaacattttt tggcatcctc catcacctgc atgatggcat
    34621 ctacttcatt tggaaaagct aaacgaattt ccatcttttt tcctcatttc tgactagttt
    34681 ctcccatcat agcataattt aagtatttct acaagcagtt aaaacttgac tttgtgtttt
    34741 tgttatttta taatctagtt atcaaaacta tataaaaagg agttgaaaat gaaaactacc
    34801 ttttcctacc caaaatgggc agaaattcca aacattgacc tctatctgga ccaggttttg
    34861 ctctatatca atcaggtctg cgcccctatc tctcctaata aagacaaggg cctaacagca
    34921 tctatggtca acaattatgt gaaaaatggt tacctgacaa agcctgacaa aaaaaaatac
    34981 caacgccaac agattgcccg tttgattgct atcacaaccc tcaagtctgt attttctatt
    35041 caagaaatag cccagacact taatactcta caaactcaag caagttcaga ccaactctac
    35101 gatgcttttg tggactacat gaaccaagga attgacccag ctaaccctat tatccaaacc
    35161 agctgccaaa ccgttaaact ctatcatcaa actctagact taatcgatca tactcaagag
    35221 gaggtaatcc aatgaacact agtcttaaac tcagcaaaca actcagtttt ggagaggaga
    35281 ttgctaatag cgtgacccat gctgtgggtg cagtcatcat gcttatcttg ctgcctattt
    35341 catccatcta tagttatgaa gcacacggat ttttatcctc tatcggcgtt tccattttcg
    35401 tcatcagtct ctttctcatg ttcctatcat ccaccattta tcactctatg gcctatggtt
    35461 cgacccacaa atatgttttg cgaatcattg accattctat gatttacgtt gccattgccg
    35521 gctcatacac gcccgttgtc ttgaccttga tgaataactg gtttggctat ctgattattg
    35581 tcatccaatg gggaacgacc atctttggta ttctctataa aatctttgct aaaaaggtca
    35641 atgagaaatt tagccttgct ctttacctga ttatgggctg gttggttctg gctatcattc
    35701 ctgccattat cagtcaaacg acacccgttt tctggagtct catgataact ggcggactct
    35761 gttatacagt tggagctgga ttttatgcca agaaaaaacc ttatttccac atgatttggc
    35821 atctctttat cctagctgcg tccgcactcc aatacatcgc tattgtttat tacatgtaaa
    35881 aaagttgaga agttcaatct caactttttt ctttacacat attgataaag tactggtgca
    35941 agcgcacatc atcagtcaat tctggatgaa aagaacttac caacatattt ttttcttggg
    36001 ctgcaacaat ttgattgttc actgttgcta aaatttctac accctcacca acactactga
    36061 taatcggacc acggataaag gtcattggaa tcttgccaac tcccttacat tctgcttccg
    36121 tgtagaaact tcctaattgg cgcccataag cattacgctc gaccaccata tccatagttc
    36181 ctagatgact ctctttctga gaagtgattt ccttagccag caaaattaag cccgcacagg
    36241 tcccaaacac tggtaagcca gatagaatgg cttctcggat gggaagtagc atgttctggt
    36301 cacgtaagag cttgcccatg gttgtagact caccaccagg caaaatcaaa cccgacaagt
    36361 cactctgatc ttgctgaaaa tcatctagat ttctgagttc tacactctcg acacctaatt
    36421 gatctagcac ttttgcatgt tctgcaaagg ccccttgcaa ggccaatatt ccgattttca
    36481 tctattttcc tcgttcagcc atgagaattt ggatttcatt ttcattaata ccaaccatgg
    36541 cttctcctaa atcttcagag atttgagcta ggatttgagg attacggaag ttagtcacag
    36601 ccttaacaat ggcactcgct cgtttaacag gatctcctga cttgaaaata cctgaaccga
    36661 caaagacccc ctctgcccct aattgcatca ttaacgcagc atctgctggc gttgcaacac
    36721 ctccagcagc gaaatttaca actggcaatt ttccatgttc atgaacatat tggaccaatt
    36781 ctacagggac ttgcaaatcc ttggcagcaa cataaagctc gtccttacgt aagttttgaa
    36841 tgcggcgaat ttcctgattc atcatacgca tatgacgaac agcttggacg atatcccctg
    36901 tccctggttc tcctttggta cgaatcatgg aagcgccttc agcgatacga cgcaaggctt
    36961 cacccaaatc cttagcacca cagacaaaag gaacttggaa ttctttcttg tccacatgga
    37021 aacggtcatc agctggagat agaacttcac tctcgtcgat ataatcaatt tcaatagcct
    37081 ctaaaatctg agcttcaaca aaatgcccga ttctgacctt agccattact ggaatactaa
    37141 ccgcttcttg gatttcctta atcatctttg ggtcgctcat gcgggaaact cctccagctg
    37201 cacgaatatc agccggaatt cgttccaagg ccatcacagc tgccgcacca gcagcttctg
    37261 cgatacgagc ctgttcagga ttctgcacat ccataataac accacccttg agcatctgtg
    37321 ccaagttttt atttagttca taacgatttt cagtcatttg ttttatcctc atcatttgta
    37381 ttggttgcta ccttttcatt ttaagtcaga acagaatgaa gcacaagata aaaaaactat
    37441 aattgtatgg ggacagattg gctaaaaact atctgacctt aacttaaggc cagatagctc
    37501 attcattttt atttttcagc cgtaagggca gccattgtga tgtagttgta tggtttattg
    37561 aagtgtggca agaagaagag gtctgtcaat gccaatttat caattgtcac atgctcttgg
    37621 atagcaagtg agaacatgtg gattcccatg ctaattgcaa tatcatgtga aaccatttgg
    37681 gcaccaagaa tttcacggct atctttgtca aagacaatct taattgctac ttcatggttg
    37741 tcatgtttca tgaattctgg tttttgaaga tcgttaaagc ctgtttcagt tgcgttgtaa
    37801 ccagcagctt tcgctttttc aagagtcaaa ccagttgaaa ccatgtgaag accgtagatt
    37861 gagataccat ttgaaccttg aacaccgatt ccttccaatt catgtccaca agcgttgtag
    37921 gcaccaacga taccagtgcg aacagcattt gaagcaagag cgatatagct tgtatcttta
    37981 cgagcattgt cataaacagt cgcacagtca ccaacagcgt aaacgcctgg gatagatgtt
    38041 tcttgtttct tgtctacaag gaaggcaccg ttgcggaaga gttcgatctt accatcagca
    38101 agggctgtgt ttggacggaa accaactgca aggataacca tatccacgtc aaagctttct
    38161 ttgtcagtaa tcaagcgttc aactttacca tcaccttcga ttgctttaac agtttgacct
    38221 agagccaagc ggatgttgtg atcttccaag tttttcgcca tcatttgtgt gaagtctttg
    38281 tcatagtaac cgttcaagac agtatcaacg atatcaacaa ggacaacttc ttttccaaga
    38341 cgttcaaagg cttcagcaag ttcaacaccg atgtaaccac caccaacaac ggcgatacgg
    38401 tcgagatgtt ggctcttgtc agaaagttta ttgataactt cttcagcatt ttggtacaat
    38461 ttcacgaatt gtacgttttc aagagttgct ttaaattcgc ggtttccttt aacaatttca
    38521 acaccttcga ttggtggcaa gattggtgta gaacctgtag cgaaaatcaa tttctcgtat
    38581 gattctttgt gttcttttcc ttcaacttct gctgtaacca ctttgttatc atagtcgatt
    38641 gaaagaactg gtgaattcat ataaacctta gcacctttag cttctaattt gtctttatca
    38701 gaatagaaca agccttcagc accgtcaatt tgttcaccaa tccaaagagc cattccacat
    38761 cctaggaaag agatgttaga gttttgatca aatacaacaa tttcgttctc atttccaaaa
    38821 ttatccaaca tggtattgat acatgctgta ccagcgtggt tagcaccgac tacaacgatt
    38881 ttactcataa aaaatttcct gccttcattc taaatttacc ttactagtat accatttacc
    38941 gttagcgttt acaagggggg tactattatt tcagcatttt ttatcaaaaa taattcccca
    39001 tttatcctgt tttcaagcct catgaatttt atgagcatat ttcttgactt tttccaaatt
    39061 ttgtttgtga aaattctaac tttatggtat tctaataaca tgaaaataaa atgtaagggc
    39121 ttcaatttag ataattattt tatattacaa cttattttct ataagagaaa ggagttggta
    39181 gcttgactct tcgttcacat tctgaacggc taatggggac tactatcact atttcattag
    39241 tggatgaaca agccgatatc tttctccaaa aatcctttga cttgctcaaa gagcttgaat
    39301 accgcttcaa cgccaatagt caagaatctg agttgatgga aatcaattat caagcaggaa
    39361 tatcccccgt cacggttcat ccagacctgt ttgagctgat ttcacttggg ttagagcata
    39421 gcctagcgct ctctagccac ctcaatatca gcattggtcc cttaattcaa acctggcgta
    39481 tcggtttttc agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa
    39541 tcaatcctca tggtatcgag ttagattctt ctacttctac tgtgttttta aaacagaaag
    39601 gaatgaagat cgatctaggt tgtttagcca aaggatacag tgcggataag gttgcccaat
    39661 ttcttaggaa agagggggtg acttctgcct tgatcaatct gggagggaat atcctgacca
    39721 ttggaaaaaa tcaggcaaga ggggataacc catggcaaat cgggattcaa gacccagcca
    39781 atcctagggg aaatcattta atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag
    39841 gcatttatga acgtcacctg accgtcgatg gacaagatta ccatcacatt tttgacagtc
    39901 aaacaggata tcctgttgaa acggaactag cgagtctaac aatcatctct gataaatcag
    39961 tcgatggcga aatctggacg actcgactct ttggagaaag acctgcttct atcctctggc
    40021 aagtcgaaag tttggagggc atcgaagtca tcctcatcga taaagaaggc cacctaagct
    40081 gttcttcagg aattcctact ctatagagac aactgtttca atggaatttt aaaattgtat
    40141 tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt gctattgttg gaacaaattc
    40201 aaaacgttct acaaaccgtc aattgcttca atacatgcaa aaacactttg ctgacaaagc
    40261 tgaaattgaa cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag ctgacaagca
    40321 agtacctgct gaaatattgg aaattgctgc taaaatcgaa gaggcagatg gcgttattat
    40381 cggtactcct gagtatgatc actctattcc agctgttttg atgagcgctc ttgcttggtt
    40441 gtcttatggt atttacccac ttttgaacaa accaatcatg attacaggtg cttcttacgg
    40501 tacgcttggt tcatctcgtg cccaattgca acttcgtcaa atcttgaatg ctcctgaaat
    40561 caaggcaaat gttcttccag atgaattctt gctctcacac tctcttcaag catttaaccc
    40621 aagtggcgac ttggttgacc ttgatgttat caagaaattg gatgtcatct ttgatgactt
    40681 ccgtatcttt gtaaaaatca cagaaaaatt acgtaatgca caagaattgc ttcgcaaaga
    40741 tgcagaagaa tttaactggg aaaatttgta agataggaga ccgaaagaat gaaatttgtt
    40801 ggacttgttg gatcaaacta cgatcaatca tataaccgca aactcttgga atttatccgt
    40861 cgcaatttca aattcaaatt tgaattagaa gtacttgaaa tcgacgaagt tccaatgttt
    40921 aaccaagacg aaaaatggga cgaaagcttc caattgcgtt tcttgtataa caagattaca
    40981 cgtgctgatg gtgtcattat cgccactcct gagcacaacc acactatctc agcttcactc
    41041 aaatctgtac ttgaatggct ttcatacgaa gttcatccat ttgaaaacaa gcctgttatg
    41101 attgtgggtg catcatacta tgaccaagga acatcacgtg ctcaagttca ccttcgtaaa
    41161 atccttgatg ctccaggtgt taatgcctac acgcttccag gtaacgaatt ccttcttggt
    41221 aaagctaagg aagcttttga taacaacgga aatatcacca acgaaggcac tgttaaattc
    41281 cttgaaactt gcttagataa ctttgttaaa tacgtaggag tcgtttcgaa attgaaaaaa
    41341 ccaaaaccaa tcgaatcaga agacttggat tgtggaaaac caatcgctac aaccatcaca
    41401 gaagttgacc ctgacgatcc agaatgggta gaaaaagttg cagcaatcac tggtgctgtt
    41461 tctggtgata cctatgtcaa attggaccac ggtatcctaa cagttaacca aattgatatg
    41521 ttcttgaaag ctatgccatt tgaattgaca tacgctgacg acaacaacca attcctctac
    41581 tacaacaacg ctcaccaaga tccagacact atgttcgcta aacgtgtacc acctcaatca
    41641 ggtagccgta tgtcgactgt tcatggttct cttccaccag cacgtatgaa gaacgtagag
    41701 tgggttatcg gaacacttcg caacggaaac caagaatacg tccgtacgat cgttccaggt
    41761 tctcctgcag gtgttatcaa cactcacaac taccaagcaa tgtactatcc tgatggatca
    41821 tacgctggta tcaatgaaat cgtctttaac ttccaaccat ggcttgactg gtacctaaaa
    41881 gagactggtc aacgtttggt gggtggtagc ggaccatttg ctcctgctgc cggaggtcat
    41941 ggagacgccg atgctacttc tggcgcttct gattcagggg atgctggagg ccacggtggt
    42001 gacgcagacg ctacagccgg tgcaagttac taatgatagt ttttaggaac cattatggtt
    42061 ccttttttag cgaaaaaaga ctagcaaaca caaactgcta gtctctttgt tatcgtttca
    42121 tctatctttg ttaaaagaaa gaatacatat tatgaatttg ggtcatcaag actacggcca
    42181 tgtaatcctt tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct
    42241 tcgtccacaa ttttgattcc ttcaatgtgg tgacgaacaa cgcgacgata accttcgatg
    42301 tactcctcac gtagtttggc ttgttccact ttttcttctg gtgttaagcc ttctgttttt
    42361 ttctttttag caagctcatt gatacgagca atttttttcg gatccatttc ttctcctctg
    42421 taataagata aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa
    42481 acttagctgc tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct
    42541 gatcttcagc cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa
    42601 agagttgttt caattgctga cttgcaggtc ctgataaaac gagtgtttct actgcttctg
    42661 ccaaagcttt ttcttggtca ttctcaaata gtgctgaatc aactgtagca accccttctg
    42721 ccttctcagc caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt
    42781 ccttgcttac ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg
    42841 aacctgcaag aactgcttcc ttgatatctt ttagagtaga gcccatcatc ttatcaacac
    42901 gagccttgat aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca
    42961 atgcataaag gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga
    43021 tacgaaccac accttgggtc gcgcgacgaa gggcatacgg gtcattagaa cctgatggaa
    43081 tcaaacctac tgagaagaaa ctcaaaatcg tatccaattt atctgcaata gcaagcactg
    43141 caccaacctt gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa
    43201 tagcagctgc taccgctgga gtttcaccag caagaagggc atatttttca cccataattc
    43261 cttggagttc gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg
    43321 ctgcacgagc aaggtcaact gtttcatcca ctgacaaacc agctttttct gccaaaagta
    43381 cagtgatttg acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg
    43441 tgacattgtt taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga
    43501 agaattctcc gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt
    43561 tcaaacgctc tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt
    43621 gatcacgaac aacaaagtaa cgctggtgtt ccttcataga agtcaccaag acttcttctg
    43681 gaacttcaag gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat
    43741 tcaagacttc attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa
    43801 ttttcttgat ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact
    43861 gcttacgaag gtcttcttca tagctcaagg ctgactgaat tttagtttct ttccccaaga
    43921 aacgatggcc acggctcaca cgacctccct tgatatcaag gaaatccaag tcaaactctt
    43981 gctcatccaa gagaacagtt aaagtgtgaa cagggcggat gtattcaaag ctatttccag
    44041 cccagtgcat gctgacaggg aaagtcaatg acttcaagac atctacaaca ccaggaacaa
    44101 tggcctcaac tgcttgacca acttcttcct tagtgacata gacatattct tcacccttga
    44161 tttcacggaa ttcgatatct tcaacagtca agccttttcc acggacaaat ccttgagctg
    44221 ctttggtgaa gtttccatca ctatccaagg caattttctt tgctggtccc ttgaaatctt
    44281 ctgtcaaatc agactgtttg tctgataaac cagtcacacg aacagccaaa cgacgtggtg
    44341 ttgagaaggt ttgaatggct tcaaaagaca ggcggttttc cttgaggaag gctgccattt
    44401 tttcgcctag ttgtttttca cttggtgtga caacataggc tggtaattct tcaagaccga
    44461 gttctactaa taagtttttt gtcatgtttt ctcctttaca ttttcttcaa tcttttttga
    44521 tatgcacctt aggtactggg gacgtcgcta actaactctg tgagtctgta tggaaatcca
    44581 atgctaaatt tatcaagatt tccaacaatc tcatcaaagt ggatttagct gactgatttt
    44641 tgaacctaag gtttcaaaaa tccccacata acagtacggc ggtgcatatc cctctagcaa
    44701 gtcttcgact tgcctctaac gattttagag tacagtatta ctcactattc tgcgtcttct
    44761 gctaaaagtt taactcgtgt ttcttcatcc aaaagtgggt aacctaggcg tttgcgttct
    44821 gcaacaaagg ttttggctac aacacgggcc aagttacgga tacgagcgat atagcctgca
    44881 cgctctgtta cagatacggc accacgcgcg tcaagcagat taaaggtatg tgaacatttg
    44941 agaacatagt cataggcagg gtgtaccaag ccttcttcta atgcacgacc agcttctttt
    45001 tcaaacttat caaagttttc aagcaacatt tcttggtccg aaatttcaaa tgaatatttt
    45061 gagtgctcat actcaggctg gataaagatt tctccgtatt ttacaccatc agcccactcg
    45121 atatcataga cagagtctac ttcttgaatg taagaagcca agcgctccaa accataggta
    45181 acttccgcag tcacagggcc agttgccaat ccaccgactt gttggaaata agtgaactga
    45241 gtgatttcca ttccgtcaag ccaaacttcc caaccaagac cagctgaacc agttgatggg
    45301 ttttcccagt tgtcctcaac aaaacgaata tcgtgctcca aaggattgat tcccaatttt
    45361 tccaaagact caaggtaaag ttcttggata tttgatggag aaggcttcat gaccacctgg
    45421 aattggtggt gttggtagag acggttaggg ttttccccat aacgaccgtc agcaggacga
    45481 cgtgatggct ctacataagc tgcattccat ggctcaggtc cgatagcacg aaggaaagtg
    45541 taaggactca ttgttcccgc acctttttca ttatcataag cctgcataag catacaacat
    45601 tggtcattcc aaaattgttg caaagtaagg atgatttcct ggaaagtcaa tttcttagac
    45661 attgtttact cctttttata taaattactt gcgacatgag tctgcctcgt cgattatacg
    45721 aggcaagacg agttagtact gcgtctagct caggcactct agtgctgagc gtggggcagt
    45781 ccgactgtaa ggaggtttct gccactgatg cagtgaaatg ttaatttctt agacattgct
    45841 tactccttta gtttttatat ttctttttca attaatttct gctgaacaaa ccaatttaac
    45901 aagggaagag ttttatctgt atttgcccat agatgataag aatctaagac cgcttgtaca
    45961 ctacctaaat tttctaccaa cttatctact gtcaaaaagc tgcgccagta ttcataaaaa
    46021 atacttgcat agttcttatc ataagtcgaa gaaccaaaat cattcaatga atgccaacca
    46081 tacttcttct gaaaaagttc tactagagat tgattacaaa ttttttccgc ttgaaattcc
    46141 tcttctgtca agaaatactt gcgactaata tattcaacca tcccctcttc gaaccagata
    46201 taagagtcag aaccatcaaa atcatctaaa aaatgctccg accaatgagc taactcatgt
    46261 cctacaatat gtaagaggaa attttcagat aaagaatgat agtgactttc tattgcttga
    46321 gtttgctcag aacactcgta gtccatcaac tgatacaaat acaactcttt ccaaacagct
    46381 aaatcaggcg tcataaccac tcgtctatta tttgtatagg ttggaacagc actttcccta
    46441 ataatctgtg tagcagcatt aaaatctgac caaataacgg gttgcggtaa atcacagact
    46501 gcaagttcat tctttaaaaa agattgataa tctttcaact tttcagtatt tcttactaca
    46561 aaatcacgaa atgtagctag ttgactatcg tcttttacaa gataaaggtt gtccacggct
    46621 ctcctttctt tcacacaata gactgaataa gcaaaagaac cacatctgac aatcctaggt
    46681 tgatttaacc taggggcgtc agaaacgcgg ttccacccta atttattact tcattgtttt
    46741 tgaaaatact acagaaagcg ccagctcatt attttgccct acttggctcc cactgtccca
    46801 agctcgcttg aagaacgcca taagactttc tttcctgctg actattatat caaaaattag
    46861 aataatgtac aattcttttt atgattttct agaaatccac atcatcaact cgtggagccc
    46921 ccgactgaac agcagtcgtt tttaaggttt ctctctcctc atgactcagt tcaattccaa
    46981 aacaatcaag attagcttga atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc
    47041 cttctgccaa gctccaggcc aaggctatct gagcaaccga ttttccgtga tttgctgcta
    47101 tttcttggac ttgcttgcta tcaaacagtt ctccttgtcc aaaaggcccc caagcttcca
    47161 ataaaattcc cttttcacga cagtaagcta cgacttcctc ttgatacaca cctggcgcca
    47221 agcgaacttg attgaccgca ggaacgatag ttgcagtttc aagcaaggca tccaaatgat
    47281 ggggaagaaa attgctaacg ccgatagcac ggattttccc ttcttgatag aggtcttcca
    47341 tcgctctcca aacttccgca ttgcgagttt tccatgcgtc attttctctg agcggttttg
    47401 ggttcggcca atgaatcaaa tacaaatcca aataatccaa gcccagtttt tctatagatt
    47461 tttccaaagc ttgacgagtt tgctcatagg tttgctgact attccaaagc ttggtagtta
    47521 cgaacatttc ttcacgtgga actccgctat ctttgattgc ttgaccaaca ctttcttcat
    47581 tctgataaat cgccgccgta tcaatatgac gataaccagc cttcaaggct tctaacactg
    47641 cacgataggc ttcttctcca tccttagcct taaaagttcc aaatcccaat actggaattt
    47701 ctactccatt atttaattga taggtattca tatgcttctc cttctatttt ctttatcatt
    47761 tatagcataa tttttttgct aattagtact atcttctgta aaaaataagt ctatcacata
    47821 tctgacagac ctattttttc ttgcttattc atcacgacta tagtacagct catgagcttt
    47881 taggcgagta ttgagcatct ctggtatggt cacaaaggta taaccttgat ttttcaaata
    47941 ctcaatgacc cttggcaagg cattgactgt cggactgtga atatcatgca tcaaaacgat
    48001 agatccgtta gctacttgat gctgaatttc tgtcaaaata gatgcttcat ttttactctt
    48061 ccagtccaga ctatccacat cccacatgat aaagctcaaa tccaagctat tgcgaatatc
    48121 atctgtaata gcaccataag gtggacgcat gagtttagaa ctagaaccca gcactttagt
    48181 tagcacatcc tcagtatcag taatctgctt tttagcttca tcaagagaga gttgcgagag
    48241 aatcggatgg ctccaactat ggtttccaac aacatgacct tcagatttta tcctcttcac
    48301 caagtcctca ttcccagaaa catttttccc aagcacaaag aaagtcgctt taataccata
    48361 tttagctagg gtctctaata cctgcggggt cgttgctgga tttggaccat catcaaaggt
    48421 tagagcgaca actttttgat atttcttatc aaagtaagat tggtacaagg ccgcatcttt
    48481 ttcgagtaag tacgaagatt ggataacatc aaagaaagca gatactggca aggctatctc
    48541 ttctaaattt tcaaccacag gacttggata aaggataatc tgactatcct tgtaatcaaa
    48601 attccatgca gacaagtctt ggtcagagaa gttttttaca atctgctcac tctggtcttg
    48661 ctctattttt ttatcctcta tgaaggaggt caactctttt atcagctgtt ccttagcctt
    48721 actagcatct gaaaacagtt ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac
    48781 ctttcctaga ctggtctttt cagtctcttc aaccttaaaa gcaactaaat catagatttg
    48841 tttggtcaca ttacgattaa cgactccctt taaacctgac tcttcttgct ctgtatagta
    48901 gaaaacaaga ttgtccttac tttctagctt gtccttaaca tcttgattta tcaactccct
    48961 aacagaggaa atcactttct ccccttggag aggataatag gcaatcactt cggcttgccc
    49021 ctgacgaaaa tgctccttct gatttccctc actcaattga tcatctttct cttttttgag
    49081 cgattcaatc ttttgctcaa aacttttttg ctggtagatc ttaaaagcaa taaatccgcc
    49141 taataggcaa atagaaattg ctaaaatacc aatcaaagcc aataatacat gtctcgtttt
    49201 cccgtgtctg ccacgtccta gtctactttt attcatattt atatcataac aaatttgagc
    49261 aataatttca atgatacaat ttggcaatcc acaattcctc tagcaagcca aagcatctta
    49321 catcaactcc aacatccgta tctgtagaga ttatgtagtt ttctatctat ggaatttcta
    49381 gtagattgaa gctagaatag tagacctata cttctaaaac attgttagaa atcgatttga
    49441 ttgtcctgat cgatttgtcc tgttctcatt tcattttact ataaaactat gaaaagctag
    49501 gtcatctgag aagtaattac tatcgacaat tgcgatagcg tatactggtg cgatttgttt
    49561 gtagctctgg tgggtatcac cttcacgttg gcgaattttt tctaggtttt gattaacctg
    49621 actgcgcaga taagcccata ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc
    49681 gatgataact tagattccat tatctaactc cgccaagacg tctatactag tatagaaatc
    49741 ctgcgctgag tagggcatgg aaggcaagac gtgaatgtta cttccctcca aaatcgtcac
    49801 attttttgct ggcaagtcca gcatatcgcg gataaattga caaatcatta gttgggctga
    49861 tacccggatg tctgagaatc ctccttttcc tccttctatt atagcacatt tttaaatcta
    49921 ggtttgctag attctatgct tctatctatt tattcggaaa agaaagcttt tcttcagaag
    49981 aaagctagta gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
    50041 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
    50101 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
    50161 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
    50221 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
    50281 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
    50341 acatgttatt ctcgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
    50401 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattacc acgagaaagc
    50461 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
    50521 tgccaaatac tcttccaaga tgcctgactt gttggctgga caaacaccaa atgtcttttc
    50581 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
    50641 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
    50701 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
    50761 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
    50821 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggga agcaagtcca
    50881 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat tttcacacat
    50941 gatccagcaa ccagatctga atctctacca aacttggctg gatgatgcag gctctgttca
    51001 tgagctacta tataccatgc gccagactgc tggcattaga tttgaggcag aaaaatgaaa
    51061 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
    51121 cccattcaaa ctcaactatt tgagcccctt cttgctggag aaaacctcct aggagtgagc
    51181 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
    51241 aaaaaagccc aacaactctt gattctagca ccaaatacgg aacttgctgg acagattttt
    51301 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
    51361 tcaagtcaga aacgacaaat tgaacgcctt aaaaaggggt cagaaattct gattggaact
    51421 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
    51481 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
    51541 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
    51601 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattgaac
    51661 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
    51721 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
    51781 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
    51841 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
    51901 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
    51961 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
    52021 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
    52081 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
    52141 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc a
//
LOCUS       DAVFJR010000010        48251 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVFJR010000010 DAVFJR010000000
VERSION     DAVFJR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.010"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            486..605
                     /locus_tag="VU722_000798"
     CDS             486..605
                     /locus_tag="VU722_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU1771812.1"
                     /translation="MPDIVFKIEFFHSDSLIFFYTSDDKSNLQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VU722_000799"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VU722_000799"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU1771813.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKAMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLHGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVRAALGEHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VU722_000800"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VU722_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU1771814.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="VU722_000801"
     CDS             complement(2517..3044)
                     /locus_tag="VU722_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU1771815.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /locus_tag="VU722_000802"
     CDS             complement(3180..4376)
                     /locus_tag="VU722_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU1771816.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELET
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TVGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9341)
                     /locus_tag="VU722_000803"
                     /pseudo
     CDS             complement(4466..9341)
                     /locus_tag="VU722_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            9630..11260
                     /locus_tag="VU722_000804"
                     /pseudo
     CDS             9630..11260
                     /locus_tag="VU722_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(11819..13426)
                     /locus_tag="VU722_000805"
     CDS             complement(11819..13426)
                     /locus_tag="VU722_000805"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU1771817.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13816..14403)
                     /locus_tag="VU722_000806"
     CDS             complement(13816..14403)
                     /locus_tag="VU722_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU1771818.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14531..14980)
                     /locus_tag="VU722_000807"
     CDS             complement(14531..14980)
                     /locus_tag="VU722_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771819.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKNILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(14985..15374)
                     /locus_tag="VU722_000808"
     CDS             complement(14985..15374)
                     /locus_tag="VU722_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU1771820.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15402..16052)
                     /locus_tag="VU722_000809"
     CDS             complement(15402..16052)
                     /locus_tag="VU722_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU1771821.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16042..16605)
                     /locus_tag="VU722_000810"
     CDS             complement(16042..16605)
                     /locus_tag="VU722_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1771822.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16770..16988)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17042..17545)
                     /locus_tag="VU722_000811"
     CDS             complement(17042..17545)
                     /locus_tag="VU722_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU1771823.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSRMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17738..18568)
                     /locus_tag="VU722_000812"
     CDS             complement(17738..18568)
                     /locus_tag="VU722_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU1771824.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(18553..20235)
                     /locus_tag="VU722_000813"
     CDS             complement(18553..20235)
                     /locus_tag="VU722_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771825.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLSLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20337..20594)
                     /locus_tag="VU722_000814"
     CDS             complement(20337..20594)
                     /locus_tag="VU722_000814"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771826.1"
                     /translation="MKIKEKTRKQVAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20601..21149)
                     /locus_tag="VU722_000815"
     CDS             complement(20601..21149)
                     /locus_tag="VU722_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU1771827.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21164..22012)
                     /locus_tag="VU722_000816"
     CDS             complement(21164..22012)
                     /locus_tag="VU722_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU1771828.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQLVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22201..23550
                     /gene="trkA"
                     /locus_tag="VU722_000817"
     CDS             22201..23550
                     /gene="trkA"
                     /locus_tag="VU722_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU1771829.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGGDFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23554..24993
                     /locus_tag="VU722_000818"
     CDS             23554..24993
                     /locus_tag="VU722_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU1771830.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            25079..25879
                     /locus_tag="VU722_000819"
                     /pseudo
     CDS             25079..25879
                     /locus_tag="VU722_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            26752..26931
                     /locus_tag="VU722_000820"
     CDS             26752..26931
                     /locus_tag="VU722_000820"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1771831.1"
                     /translation="MKTVTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVRE
                     YITDSISTNTIEEAR"
     gene            27542..27826
                     /locus_tag="VU722_000821"
     CDS             27542..27826
                     /locus_tag="VU722_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771832.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVKKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27819..28067
                     /locus_tag="VU722_000822"
     CDS             27819..28067
                     /locus_tag="VU722_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771833.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLPATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVAKQI"
     gene            28163..28381
                     /locus_tag="VU722_000823"
     CDS             28163..28381
                     /locus_tag="VU722_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771834.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDAFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28664..30988)
                     /gene="pflB"
                     /locus_tag="VU722_000824"
     CDS             complement(28664..30988)
                     /gene="pflB"
                     /locus_tag="VU722_000824"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU1771835.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGSTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            31336..32397
                     /gene="dinB"
                     /locus_tag="VU722_000825"
     CDS             31336..32397
                     /gene="dinB"
                     /locus_tag="VU722_000825"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU1771836.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIELMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVVLNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(32544..33389)
                     /locus_tag="VU722_000826"
     CDS             complement(32544..33389)
                     /locus_tag="VU722_000826"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU1771837.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            33644..34585
                     /locus_tag="VU722_000827"
     CDS             33644..34585
                     /locus_tag="VU722_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU1771838.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYEVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKVEKCVNDLMAEFNSVITTVTGIDNRLGAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
     gene            complement(34964..36853)
                     /locus_tag="VU722_000828"
     CDS             complement(34964..36853)
                     /locus_tag="VU722_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU1771839.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHTKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGAELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLHLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGGEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVLYYWKLQLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINFYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            36992..38557
                     /locus_tag="VU722_000829"
     CDS             36992..38557
                     /locus_tag="VU722_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU1771840.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMGKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILHFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            38557..39297
                     /locus_tag="VU722_000830"
     CDS             38557..39297
                     /locus_tag="VU722_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1771841.1"
                     /translation="MTQVILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(39406..39621)
                     /locus_tag="VU722_000831"
     CDS             complement(39406..39621)
                     /locus_tag="VU722_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771842.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(40492..41742)
                     /gene="ilvA"
                     /locus_tag="VU722_000832"
     CDS             complement(40492..41742)
                     /gene="ilvA"
                     /locus_tag="VU722_000832"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU1771843.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGISTYIKETSPEIEIIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHVQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(41792..41932)
                     /locus_tag="VU722_000833"
                     /pseudo
     CDS             complement(41792..41932)
                     /locus_tag="VU722_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            complement(42117..42353)
                     /locus_tag="VU722_000834"
     CDS             complement(42117..42353)
                     /locus_tag="VU722_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771844.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(42460..43482)
                     /gene="ilvC"
                     /locus_tag="VU722_000835"
     CDS             complement(42460..43482)
                     /gene="ilvC"
                     /locus_tag="VU722_000835"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU1771845.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYIVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGLRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(43548..44024)
                     /gene="ilvN"
                     /locus_tag="VU722_000836"
     CDS             complement(43548..44024)
                     /gene="ilvN"
                     /locus_tag="VU722_000836"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU1771846.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(44017..45717)
                     /locus_tag="VU722_000837"
     CDS             complement(44017..45717)
                     /locus_tag="VU722_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU1771847.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(45917..47584)
                     /locus_tag="VU722_000838"
     CDS             complement(45917..47584)
                     /locus_tag="VU722_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU1771848.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(47587..47952)
                     /locus_tag="VU722_000839"
     CDS             complement(47587..47952)
                     /locus_tag="VU722_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1771849.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(48109..>48251)
                     /locus_tag="VU722_000840"
     CDS             complement(48109..>48251)
                     /locus_tag="VU722_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU1771850.1"
                     /translation="NRSHAMNQTKRAVKPNLQKVTVLIDGKPKKVWASARALKSGKVE
                     RV"
BASE COUNT        14383 a        10486 c         8781 g        14601 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttaaaattg aatttttcca tagtgactcc ttgattttct
      541 tctacacgtc tgatgataaa tctaatttgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acaaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaaact agtatagata tgttctccaa gagccgctct gacaacttca tcttctgtca
      841 aagctttcaa agcgttatga agagttgatg gaaggtctgt aataccagct tccttacgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccatg caaaccaacc tccaacagaa ccgccatagc gatgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatagcagt atagttgtag gcatgcttaa
     1201 tcaaaccgcc aagaaaatgg taggctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggtttcgcca taaaggttgc gtaaagccca tgtttgcgag
     1381 caatggtttt aacaacgagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 catacttaaa gtcaatctcg tgttgaccaa ccgcaacctc gtggtgactg gcttctactt
     1501 caaatcccat tttggtcaag acattgacaa tctcacgacg tgtattgtcc gcaaggtcag
     1561 taggcgccaa atcaaagtag ccacccttgt cattcacttc gagcgttgga tctccatttt
     1621 catccagttt aaataggaag aattctggct ctggaccaag gttgaaagat ttgaatccta
     1681 cttcttccat atgacgaaga gctcgtttca aattaccacg agggtcccct gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca aacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtcag ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acatagcctt gttcgacaag accttatcta
     1921 attgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgaaaaca
     1981 tgagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcatgag ttttctcctt aatgtatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaag cgaccctgtt ggaggagttc attgtgaagt gcacggcgca
     2161 cctcagtctg actcaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattaataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaagaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac tcctgctttg
     2701 ttgttcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctt atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaat
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttaaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ctgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atatcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccaatt
     3661 tcgatacctt gtgctttgta gaatgtataa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgtttccaat
     4081 tccgcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc atactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctgacca agcctgctat tagggattca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactgtgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtgt ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcgt aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaat ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg ttcttttcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggcag ccaagagttc ttgagcctca cctgttaagc gatcaagctc tgtcttttct
     5521 tccataaatt tctcttgacc attcagagct ttatgagctt ctgtcaattt attaagtcgg
     5581 tcattgactt gatcttgggt gctagtttca tggtctttca acacttgttc ggccgcttca
     5641 attgctttca agaaagcttc ttttacttct ggtgaagcaa agttatagac caccttgttc
     5701 ttagcagctt caacttctgc taatttttgt ttgaggtact catcgttcaa tgctgctttt
     5761 ggagatacca aaacatcaaa gttgacttca tgaccttggt aacgaagcgt caaggtttga
     5821 cgaccagtct tttgagcatc gtaaccagaa atttcaactc cctcatcagt aaaggaatgt
     5881 tcttccatgg tgtcattgct ataagccact gcaaagcgtc cttcagacaa gtctaagcta
     5941 tcaccaacta ggtaatcttt tttcggttcc tgacttactt caattcccaa aatagttttc
     6001 ggacttgctt catcttggcc agtgacagtc actgacaaat tagcatttac tggttgtccc
     6061 aaatattgga gagtaagatt ctgttctccc ttatgatgcg tatcaaaacc tgatactgat
     6121 acacctgcgt gatttagacg aatgagttcg tcctcagttc ctccttcata ctgaactcga
     6181 agaacaccac ctctaaggtc caaatcctcc ccttcggcgt agcttatttt cttaggtcct
     6241 gtttctaggc tgactaactt gattcttctg ccatcttttg gaacggaaac tgctaggaca
     6301 ttactaattt ccttgcctgg caactgggta cgataataaa gaagaccaga ttgatttgtc
     6361 aaatccaatg gtgcacttgc taggtctcct ccaacttcgc tcttcaaggt tgcgagcgga
     6421 gtttgagaat ttggattatc ataaacggta atagttgctc cagccggtac atctgcaaag
     6481 ccaacttgta ccttgttatt gcctagagaa cgggctgcag ccttggccat cggaatattt
     6541 acactctcag tatcaagctt ttcatacatt ttccagttat agatacgaat agccttccat
     6601 ggagttccat tgtcagaagt gacaacattc aagtaccagt cttgagcagt gattggttta
     6661 tcaagagtga tatctgtcac atgtgctttg ttaccacgga cttccttagc tagcttccac
     6721 tcacaatctg catctttata ataaaggtca aagtctttgg tgttcatcaa gccatcgtta
     6781 acagactcac caccagcccc tgcatgatcc atgacccatc taacaacggt acgtggcttg
     6841 gtcaaacgaa tatccacact accactcaac tgagctgaag accatttatc tgacaagcta
     6901 gtaatggtac cgttcaacat accttcaata ccttctccac cttcagtctt agggaaagta
     6961 ctatcaataa ctgttgcacc tggaacgata ttttcagcta gtggttttgg taggctggta
     7021 tcttttacag tcatacccca atcaaaggtt gtggttgcag cttctgaacg aactccattt
     7081 ttaccgactg ctacaacctt cagttcttga gttgtaccct gagcacttgc tgagcggcta
     7141 acttttggta gataaatagt tgtagaagat gagccagtta gtaatttcca gctgtctcca
     7201 tctttttcat aaacttcata gaaatctgca tccttgttgc ctttaaattg cacaactgct
     7261 tccgcttctt gggcattttt aagcgattgt ttcactacag aaaagcttgt tggcgattgt
     7321 ggctcttggt gattgtccga gatagttaat tgtccgaggt tgaactgata atcttttaca
     7381 gcaccttcat gctcgaaaaa tagtttgact gcatagatgg ttttacctgc tagtgagctg
     7441 agatcaaatt cttcatttgt ccagttgtca gaaagggtta gctctttcca tgcatctgca
     7501 tcatcgaatt tgtagtctgg agttgtagag aatgccatat aaactttaga accttttcct
     7561 ctcttgtggg caacacgaag tttggtcttc tcagttactt ctaacttagt agaataaagt
     7621 ctcacatcct gatctgtctt accggctaca tcaccagaga atttaaggga atttccgcca
     7681 ttataggcat ctgtaaaatc atattctgca cgaagttttt cccctgttga agtctgccac
     7741 cagcgccatg ttggaagaac acctgatact gaacgataat tccactcaga atccttagaa
     7801 accttaccat ctacgaacca ttttttacca tgacctgtat taaaagaagt agtaaaagta
     7861 ttacctaccg ctggcgtacg gtccgcaact aggttagcaa taccatacca atctttgtca
     7921 cctggttttt ggccagtagg gtctccttga taacctgtaa agaagatatc ttcattttta
     7981 tgataatctt caccagtttt tcctaaactt gtaatggtat ctggggcaaa taaaccaaga
     8041 gaaaggcgca atttcccatt ttcgtctaaa atgtcattcc acttaacctt tgtcttgtag
     8101 gaaccaccct gttgcaattc caaacctgca aatacatcat aaggattacg accaatccag
     8161 ttggcagttg caatagtgta atcattttta gccttatccc agttaaagtt agcaaagaag
     8221 ttatctgccg gaaccttatc tccttctggt tgcatgaatt ggtagttgta ttctcccaaa
     8281 ccatcttgat ggtaacgtcc ataattatag gtcatggcat cataccaaga atacttgatt
     8341 ggatggttta ccttagcagc atattccttg ctatagagca taaactggcg catcttttct
     8401 ccaagaggtt taaccaaatc tccagttgtt tcttggttga tgaaatagcc atcatagcca
     8461 taatacttgg ccatgtctac caatttacgg gcaattggga agctaccatc tgcgtcttgc
     8521 ttcaaagctt cagcaaatct ttcttgatct gcaatactat tagaccagtt gaagaagagt
     8581 gtaccgtata caggaacccc attacggtga cctgcatcaa taacgtcagg agttggtacg
     8641 agaccttccc agaaaaccat tgaatctaga tattgccaat agtcaaaagc ataggccttg
     8701 aactcttctc caccaacaga agcatggtct tttgctttag aattggtgtt tgataaggct
     8761 tgaacttttg cttccttgct agctttttca ttgactaaat gacctgtccg acgtgaagcg
     8821 aggataacag atccgcggtt aatagcatca tcttcacgag cacctggttc ccattttaac
     8881 aattcttccc aagaattaaa tttgatttcc tttggtttta atgttttttc tgtattttta
     8941 gggacatctg gctggacttc tttttcagtc ttattagctt ctgctgctgg cttagactca
     9001 tccccttggt tagttgcttc gggctttgct tctgcagatg gtgtttctgc aaccacctca
     9061 cctgcttttt cctctggttt agctacgcta gctgcttctg ccttttctag cttgttttct
     9121 ctagcatgtt ccccttcatt ctgcttatca acttcattgg tcgaatgctc actctctcct
     9181 gaaacaagct ctgtattagc tccgctattt tcaggaactg cagtttcttc agccaaggct
     9241 ggaccagcaa ataaaacagc accaatcatc agcgagcagg ctcctactga taacttacga
     9301 atactgtaac gacaacgtct ttcaaaaaat ggattcttca ttttctcctc ctaaaagatt
     9361 gattttgttg ttttcaagaa agcgctttat attctgtagt tttttaactc tagaaccatg
     9421 ataatcacat ttttatccta aaacattttt agacaaaaaa caatagctgt tttcacaaat
     9481 ctaaaataag gttaaaaact cttaaaaata atacacttat caattataat tttcttttac
     9541 aaacttgaca ttaacacttg ttagatttac ttttatcctt taaaatagaa taggagatat
     9601 tccgcgatta tttttcggag gaaaaagaaa tgtccattaa ttggcaggaa attttatttc
     9661 actttttagg tggtctgggg ctattcttat atagtatcaa gaccatggga gacggtttgc
     9721 aacaagctgc tggagatcgc cttcgttttt acattgacaa atatactagt aatcctttct
     9781 ttggagttct ggttggtatt gggatgactg ctctaattca gtctagttct ggtgtaacag
     9841 ttatcacagt cggcctggtc agtgccggtc tcttaacctt acgtcaggct atcgggattg
     9901 tcatgggtgc taatattggg acaactgtca catcctttct catcggtttt aaattaggta
     9961 actatgccct acctatgctc tttatcggtg ccgtctgtct cttttttaca aaaaatggac
    10021 agtcaataat atcggacgta tcctctttgg tgtcggtggt atcttttttg ccctcaatct
    10081 catgagcggc gcaatgactc cactcaagga tttacaggtc tttaaggact atatgattga
    10141 gctaagtaag aatcctgttt tgggtgtctt tgtcggtacc ggcttgacct tgctaattca
    10201 agcttcttcg gctaccattg ggattttaca aaacctctac gccggcaatc taattgacct
    10261 acagggagct ttgccagttc tatttggtga caatatcggg acaaccatta cagccatcat
    10321 tgcctcttta ggggctaata ttgcagctaa acgggtagca ggagctcatg ttgccttcaa
    10381 cgttatcgga acagtcgtct gcgttatttt tctagttcct tttactgtcc tgattcattg
    10441 gtttgaagct acgctaaatc tagcaccgga aatgaccatc gcctttgctc acggaacctt
    10501 taatattacc aacaccattg tccaatttcc atttatcgga gctctggctt actttgtaac
    10561 caagattatt cctggagagg acgaggttgt caaatacgaa cccttatatc ttgatgaaca
    10621 tttcatcaaa caggccccat ctatcgctct aggaaatgct aagaaagagc tcttgcactt
    10681 aggaaactac gctgctaaag cctttgacct ttcctataag tacatcattg acttggatga
    10741 aaaagttgct gaaaaagggc ataaaaccga agaagcaatt aacaccatcg atgagcaatt
    10801 aacacgttat ctcattgccc tttcaagcga agctctcagc caaaaagaaa gtgaagtgct
    10861 taccaatatc cttgattcct cccgtgattt ggaacggatt ggagaccaca cggaggctct
    10921 actcaatctg actgcctatc ttcaacggaa aaatgttgaa ttttctgatg ccgccttgaa
    10981 agaattagag gaagtttacc gccaaactag tgactttatc aaagatgctc tggatagtgt
    11041 ggaaaacaat gatattgaaa aagcacgcag tcttgtagaa cgtcatgaaa caatcaataa
    11101 gatagaacgt gttctcagaa aaacccacat caaacgcctc aacaaaggcg aatgttcaac
    11161 acaagctggg gtcaacttta tcgacatcat ctcacactac actcgtgtat cagaccacgc
    11221 tatgaacctt gctgaaaagg tttttgcaga acaaatctaa gaaccaagaa gctatccatc
    11281 ataattggat ggctttttac ttttttctaa gcaagactag gctgaatgaa actgaaagag
    11341 tattctacag atatatagta tattgaaact agaatagtac acctctattt ctaaaacatt
    11401 cttagaaatc gatttgactg tcctgaacga tttgtcctgt tattatttca ttttattata
    11461 gtggattaaa ttaaaaaagt atagtatatt gaatctataa cagtacatct tgactgctaa
    11521 aatatttcta taaattaatt tgactttcct gatagagatg ttcacatctt atttcaattc
    11581 actatacaat ccagttccta aaactttgct agaaattgat ttggctttcc gaattaattt
    11641 gttcaaattt tatttcattt caatatactg ataaatccat tcactagcac agggcaagag
    11701 ggagtcgcta ttgatttcaa gggtagcagg tacatacaga ggactcctac ctcagatata
    11761 ctgcaatatc atcgtatgca aaaaacctct gagatttttc tcaaaggttc tgattttgct
    11821 aattgctgtt ctcaaccgct gcagtaacaa aggcagtgta gagttcttct ggtcggtttg
    11881 gacggcttga cagttcaggg tgatactgac aagctacaaa gaatttattt tcaggaattt
    11941 ccacgatttc taccaaacga ttgtctggag aaactcctga aaagacaaaa cctgctgcct
    12001 caaactgctc acggaaggca ttattaaact cataacggtg acggtgacgg cgttgcacca
    12061 cttcttgatt gtgataagca gcagcagcct tagagccacg tttcaactta gacggataaa
    12121 gtcccaaacg aagggttcca cccatatcct caatatcaat ctgatcacgc atgatatcaa
    12181 tgatagggta ttttgtttct ggtgcaagct ctgcagaatt ggcaccttca agacctaaaa
    12241 cgtgacgagc aaactcgata catgtcaact gcattcccaa gcagactccc aacattggaa
    12301 catcattttc acgcgcatag cggatggctt ggattttccc ttctgtacca cgttgaccaa
    12361 aaccacctgg tacgatgatc ccgtccgcat cagacaagag ttctgctaca ttctctgctg
    12421 tcacatcatt ggcattgacc caattgattt tgacttctac atcattgaca tagccagagt
    12481 gtttcaaggc ttcgaccact gagatatagg catcttgcaa ctccacatac ttaccaacaa
    12541 gggaaatctt aacttgtttc ttgaggttca tgaccttgtc caccatggct gaccattctg
    12601 tcatatccgc tgctggtgcg tctaatttca aatgatcaca aacaatttgg tccatccctt
    12661 gtgcctgcaa gttcagtgga atttggtaaa ggtgttcaac atccaacgat tcgataacgg
    12721 cttctggtgc cacatcacag aactgggcca gtttattttt aattccttga ccagctggct
    12781 cttctgtacg aataaccaac atatttggtt ggattcccaa gccacgcaat tctttgacag
    12841 agtgttgggt tggtttggtt ttcatttcac cagcagcctt gaggtaagga agcaaggttg
    12901 tatggatata catgacatta tccgcaccca catctgcctt catctgacga agagcctcta
    12961 ggaatggcaa ggactcgata tctcctactg ttccaccaac ctctgtgata atgacatcag
    13021 agtcggtcgt tagagcggca cgcttgattt tttctttcaa agcatctgtg atatgaggaa
    13081 tgacttgaac agttgcccca aggtattctc cacggcgttc tttacgaaga acttcactgt
    13141 aaattttccc agttgtcacg ttggaatatt tgttgagatt gatatcgatg aaacgttcat
    13201 agtgacccaa gtccaaatct gtctcagctc cgtcatctgt cacaaaaact tccccgtgct
    13261 ggtaaggact catggttccc ggatcaatat tgatataagg gtcaaacttt tgaatggtta
    13321 ctttgagacc acgatttttc aagagacggc ctagactcgc tgccacaatc cctttcccaa
    13381 tagacgatac cacaccacca gttacaaaaa tatatttcgt agacatagat tcctctttct
    13441 aaaatgctca aggtcttgtt aactacgagg ggatatagaa aacaagaccc tactaataag
    13501 aataatctgg gacgactgca ccagattcac aactaatact cttcgaaaat ctcttcaaac
    13561 cgcgtcaacg tcgccttgcc gtagatatgt gttcctgact ttgtcagtct tatctacaac
    13621 ctcaaaacag tgttttgagc agcctacggc tagtttccta gcttgctctt tgattttcat
    13681 tgagtataaa atacaagaag ataacttctt gaaaaaacaa aaatagctcc ctaagaacta
    13741 gggagccccg acctctaaaa gaggtgccca aacaatatga tacctaaaaa taggataatt
    13801 gtcaatagct aactcttatt cctcgctggt ttcagcgtcg tcatctgaaa actcgtcgtc
    13861 gtcttcgttg agatccacat cttctcccaa gtcatctgga gcgatttcgt tgatttctgc
    13921 atcataagct tccacttcat ttttttcatc atctggattt tcatcatcgt atgaaagagc
    13981 tggatctgct tcgtatgcat cttcgtcttc tggatcatct gcattgtagt caatggcatc
    14041 tgaatcacca tccataaagg cattgacacg ttttttctta gcttttggtg ctacttcatc
    14101 gtcgtcattt tcttcaagag cgatgatttc ttcgtcgatt tcgtccacac cataccatga
    14161 acgaagaccc catttgttgt ccccaagtga gatgaagcta ccgtcaaagt tcaactctgt
    14221 gtagaacaaa ggcaaagctt cgcggatatc gctgtttgat gttccaaggt agttttgaat
    14281 ttcgtttaca agatcgctaa aatgcatctc atgatcgcga ccacgaagtt ccaagatagc
    14341 acgcgctacc tcaatcatag atagttcact tttttcttgc ccagcaaata cttctaattc
    14401 caaagcgttt ctcctcattt atactactat cgccagagcg aacagactct gacctcattt
    14461 tatcatttac tctttatttt acgataattt tgcggaatag tcaaaggtta agggggagaa
    14521 agtggcagga ttagactaat tccaatataa aactccttcc tttttctgtt gctccatttt
    14581 ccacaaatcc aagcgacttg aaacacctcc tagaagcatg attgtaggtg tagatttcct
    14641 tgactctcaa ttctttccat ccttttactc gagccaattc aatcaaagca cttagaatat
    14701 tttttccaag tcctcgatgt tggtaagcgg aattcccaat cacaatgggg agattatcct
    14761 gagatagtgt aatatcccca attggaaacc attctccctt ctccttgact tcaatccaaa
    14821 aaagctcacc atgccgatcc aaataggaat acatggcttc caaggtcgct tgactgtaag
    14881 gaagcttcac cccatctacg aggtaaacca agttcacatc ctgataccaa gcaaaagctt
    14941 cctcacaata attgacctta taataaggaa caaaacacaa tgcactacct tttcaacaaa
    15001 agagttgctg cttgattaaa accatcacac cagttatacc attttgcttc atacccatct
    15061 tgagctagga tacgatcttc taaatcaaaa acagagtaaa tctttctttc ctcgcaagct
    15121 tgcgcataga gatgatatag ttcatcacca ccatctctat cccactcagc agaaatcgta
    15181 tcccgacctg ccaataaagc ctgataagcc ctgtgatgcc catctgtaat cagcaaacaa
    15241 tctccaaagg caagaatact gattggatcg acttggtttg tttctgccga ctggtaaagc
    15301 atctgaatat cttgcaactt cttttctgat aaatatagtt gagtcggatg aagatctact
    15361 atattgactt tcatttcttt ctcctcaagg gaattcgata ctcacttctg tttgccttta
    15421 aatcgccatt ggaagcggag cttgtcatag aagggaaact cgataaacaa gactcccaaa
    15481 cccacacaga aactggcaag aacatctgat gggtagtgaa ctcccagata gactcttgat
    15541 accagcacac tgactaggta gaggccaagg acgatttgta cgatttttct ccagacctga
    15601 tctttaatcc gctgactaag aataacaatc aaagtcccta ccatcagcgt tacagctaga
    15661 gaatgcccac ttgggaagga aaatcccttc tcctccacca gatgtaagat agctggtcgt
    15721 gggcgctggt agatattttt aaaggtcacg attaaaagac ctgccaaagc cagatttccc
    15781 agcatgaaga aactttctat cttccatcgc ttacgataaa agacaaaagc tataatgaca
    15841 acccaagtga taatcactgg aatatcaatc agatgtgtga gggatcgaaa aagaatagtc
    15901 aaataatctg gtaagtctcc tcgaatggca gtctgaatcg attggtcaaa accgaccagc
    15961 gtttcagggt aaaatttgac catgtagcca agaataacga aaagtaaaag ggcaaaactg
    16021 cccttcatta aaaatgtttg tttatctttc atagtgtttt aaggttggtt tcaaaaggac
    16081 gtacaacaac cagaatgaaa cggaaaagat tacaccctca atcaagttaa aaggtaatac
    16141 catggtcatt aggtagttgg aaagtcccaa aatttttcca atatcaaagt tagcaaactt
    16201 agcgtacaaa ggaacagcat aaacatagtt gagaaccaac atggccaagg ttaaaccaac
    16261 agttccagct agagagccta gtaggaaacg aagggttgtc cgttcctttt tccaaatcaa
    16321 agcaaatacg atgacaaaaa ctcccaaagc tacgatattc atcggcaaac caatgtaagt
    16381 attcactcct tggctgttaa gaagcaattt caatagtgag cgaagcaaga gcactcctag
    16441 agcagcaggc aaatccatga ccaccagacc cacaaggact ggcaagatac taaattcgat
    16501 cttgaggaaa gatgccgctg gtaaaagcgg aaagtcaaag tacatcagca caaatgagat
    16561 ggctgataga attgcaatgg tcgaaagtcg acgtgtgttt gtcataacag gttcctccaa
    16621 ttttctataa aatcagaaga agttggaaag gattcctcta tctattctca ctttttatat
    16681 cccaaaagtt ccctcttact ctattaaaga aaaacaaagc aagtggttac aatccggcta
    16741 taaatctatc aaaacagaca aagctattct ttcgtcttct cccatccaga ctatactgtc
    16801 ggttgtggaa tctcaccaca tcagcttgcg ctcgcggact tattttgcta agatatttta
    16861 gatttatcta ggcgtcgcag tcgaagataa tacttaaggt atatcgagac aaaacaacga
    16921 cgagaaagct aaaatagcta gtcaaattta ccgccggtcg ggaatttcac cctgccctga
    16981 agactctttt atcataacaa aaaacgcttg caagcgcaag cattttgttc attttcattt
    17041 tttatttcaa tttatccact tcataggtat ggacgagctc aagacctgca aagttctgct
    17101 ggcgaagagc ctcatagaca atcatgcaga cggtattaga cacattgaga ctgcggacat
    17161 gttcatcatt catgggaata cgaagagcct tctcaggatg ttctcgcata aaatcttcag
    17221 gtaagccctt gtcttcacgt ccaaagagaa aataatggtc ctcgtcagtc gataaatcca
    17281 cctcagaata gactttttcc gcgaatttcg aaatcagata gagttttccc ttcatccgag
    17341 acatgaaatc ttccaaactc tcgtaaaaat aaatctctag cttatcccag taatccaatc
    17401 cagcccgctt catcttgcgg tcatcaatag gaaagcccat aggcttgatg atgtggaggg
    17461 gagaattggt cgcagcgcaa gtacgcgcga tattgcccgt attttgtgga atttgaggtt
    17521 caaataatac aatgtgattt gtcatgactt gcttcctttc accattgcaa aaaaatagcc
    17581 acactgcccg gagtcaagct cagcaaacag cgtggttaag gcatcgttaa cttacctcac
    17641 aacaggtttg aagtaaatca gcgaaactac tttcttagta taacactttt agaatcattg
    17701 tcaatagaaa cgacttgatt ttttaaattt tttcaagcta tttccaaggg ttgtaaaatc
    17761 gtccctgatt ctgcaagata agtagtaaac tagctactaa aaacaaggtt gccaagagca
    17821 aggtaatata gtctcctttt ttcaaggcct gataactata ccatgtgcgt tttttctctt
    17881 tcccaaagcg gcgaagctcc atggcagtcg caatggtatc aatgcgttct agcgagctaa
    17941 aaatcaaggg cgtaataatg agcagattgc ctttgattcg ttgcataaga gaagctttct
    18001 tggataattc catcccacgc gcctcctgag acatcttgat agtaaagaat tcttcctgca
    18061 aatctggaat atagcgcaag gtcaggctga cagaataagc aatcttatag ggcacaccaa
    18121 tttgatttaa actggaagca aactgactag gatgggttgt catcaaaaag ataatagcca
    18181 gaggaatggt gcaaagatac ttaatggcca aatttagcag ataaaagagc tcctggctgg
    18241 ttagagtgta gacaccgatt ccctgccaaa tcacacttct ctctccataa agtccaaccc
    18301 catactcggg agaaaagaga tagaccatca aaacgtttaa aacggcaaat accgtcgcaa
    18361 aaacggctac aaaggagaca tctttaaagc ggatttctga taaatagagg agaaagactg
    18421 aaaagatggc aatcagcaag agcattctgg tatcatagct aatcatggcc gccaatgata
    18481 ccagaatgaa aaagagaagt ttcccagctc ctgacaagcg atgaatcaca gtatctctat
    18541 gctggtaacc gattaattta gcttgcatcc ctctctcctt tctttgtaaa atgccgttaa
    18601 atccagtgga tccacatcta gtttcttagc caagttaaag atggaggttt cttttagatt
    18661 ggcttttact aacagctcag gatcgctcaa cagactggct ggaacagtat cggcaatcaa
    18721 ttctccatcc accatgacaa ggacccggtc tgaataatcc agcatcaatt gcatatcatg
    18781 ggtaatcatg acaatggtat gccctttttg atgtaactct tcgagaaatt ccataatctc
    18841 agtatagttc ttctgatctt gacctgcagt cggttcatct aggagaataa tttcagctcc
    18901 taagaccaaa attgaagcaa tggtgacacg ttttttctga ccaaatgaca gggcagaaat
    18961 aggccaatta cggaattcat aaagtccaca gattttcaag gtttcataga ctctcgtttc
    19021 aatttccttc tcatccacac ctcgcaaacg gagccctaga gccacctcat caaaaatcat
    19081 attggttgaa atcatttgat taggattttg tagcacatat cctactcgtt ccgcccgctc
    19141 tgcaacagaa tcgcctttta tatcctgttt ttcccaaaga tagcgtcctt ccgtctgaat
    19201 aaagctactt atagccttgg ctagagttga tttccctgct ccattttttc cgacaatagc
    19261 aatcttttca ccctttttaa tatctaaatg tagggatttt aaaatcggtc tatcatcata
    19321 agaaaaagat acttcctcta gtctaaagag tgactgcaat tctgaggttt cttttaccag
    19381 ttccgtctgt aactggactt gcccttttga gatagacaag ttatccagat ctgctaattg
    19441 ttcttccttg actaagtcca cacctaattg acggagagtg gttagataaa ggggttctcg
    19501 aattccattt tgagtcaata aatcagtcgc aagcaactgg tcagggctcc cattaaaaag
    19561 gatacgacca tcgtttatca agacaatccg atccacaggg cgatgcagaa cgtcctccaa
    19621 acggtgctcg ataatcagag tcgtcgtccc ctcttcctta tgaatctggt caatcaattc
    19681 gataatatcc tgacctgact tgggatctag attggcgagt ggctcatcaa acaagagaat
    19741 cggactttca tcaatcaaga caccagccag actgactcgc tgcttttgtc cacctgacaa
    19801 atcctgagga cgctgatcca gtaaagaaag aaggtccaac ttttcagccc atttataaac
    19861 acgacctttc atctcatcta gggctgtcac atcattttcc agagcaaacg ccaaatcttc
    19921 tgccacagac aagccaataa actgcccatc tgtatcctgc aaaactgtgc taaccagatg
    19981 agacttatca tagatgctca tatcaaaggc tacttgaccc tttatcaaaa attctccata
    20041 tgtctgaccc ttgtaaatat tgggaataat cccattcaaa cactgaccca aggtagattt
    20101 acctgaccca gatggtccaa caattaagac tttctctccc ttgtaaatgg tcaagtctat
    20161 cccttgcaag gtcggttctt gttgtgtttc ataccggaaa gagaaatcct tccactcaat
    20221 tatagcttct ttcatcttac tctcttcatt cgcttcttag acttctattt tatcataaat
    20281 caagcccttc ttgcagtctc tcctcttaaa atcttagcgc caaaaagatt cctatcctag
    20341 cttacttgcc taactaatct ataaacatcg aaaaagacta gttgcccagc cttccccatc
    20401 attttatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttgcc gtaggtatgg
    20461 ttactgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca
    20521 gttctatcca caatttcaaa acactgtttt gagcaacctg cgacttgctt cctagttttc
    20581 tctttgattt tcattgagta ttagtccttt ttcaaacttc ctgcacgagt ttgggttcct
    20641 gcataggcaa gtaagagaag agttcctgca atagctacag atacaccatt ggcaattccc
    20701 gcaacaatcc cttgtgcaaa tactttttct gccgcttctt gataaatcac aacatctcca
    20761 agtggtgcca agacacccca aacaagggca tttgcaagta gttgaatgag attaaaaata
    20821 agaatatctt tccagtcaaa aacactattg atcacgcgaa cgtactttct aaaaagtccc
    20881 acaactaaac caaagagtcc gctagcgata atccaagtcc accatagacc ataaccaaca
    20941 agagagtcct tgattgcatg accaatcaac ccgacaagca aaccgataat cggtccaaaa
    21001 ataatagaaa gtagcgcttg taccgcatac tgaagctgga tgcttgtatt tggaacaggg
    21061 gttggaatgt tgatcatccc gatgacgaca aagagggcag cgccaattcc gacagcaaca
    21121 acttgtttaa ttgtaaattt gatttccata ctattctcct attttatcct tctattttct
    21181 ttatttcaat ggtccaagat gaaccgacac ctacattata ggccttggca aaggaacctt
    21241 ggttgatagc caaacctaaa cgatagagag agttgatgta aaggatgggt tgcccaattc
    21301 tcacatctgc aaatgatttg ccatagacaa gctgattttg atagaccagc atatcagcat
    21361 gatagatggt cacttcaaaa cgatcaccaa attctggttc cagcttgtaa aattcttccc
    21421 gtgtgataga ggtccaaagc gaaccgaaac gcacatccag aatatcaatg gctcccttca
    21481 ccagatgatc ttctatgatg gtcgctacga ctggaagctc tacaatctgt tccacactga
    21541 gctctggccc tacttcctca aaagtaatgt gaccactggc cagtttagca ccagtatagg
    21601 catagacatc acgaccgtgg aaggtataag aatgctctgt gttttgacgc ctattggcca
    21661 cctcagaaat ctcacgaatg gctacaatgc caacgtgttt cttgataaag gaaagcgtcc
    21721 cattatctgg cgtgacaatg tattgatttt ttgcagtctt ggcaactaca ctcttacgtt
    21781 tcgaaccgac acctggatcg acaaccgata caaacgtcgt tccctcaggc cagtaatcca
    21841 ccgtctgaaa gagacgatag ctcccctcaa aaatattata aggcgtgata tcgtgcgtca
    21901 agtgatggat ttttaaggtt ggagactctt ctaaagccac tccaatcata gccgataccg
    21961 caccatcaac cagaccaaag tctgattgta ataccagtaa attattattc attttatctc
    22021 cttgtatatc ctttatcata ccatatttca gagaaagtcg ctaatagcta tttcaattgg
    22081 ttagggtata gttttacctt atagcaaatt tcctactaaa agttcttgtt attagctagt
    22141 aggtgcattt tttcttgaaa aagggtatga tagttacatc atgaaaaagt aggttttatt
    22201 atgaaaatta tccttgtcgg agggggaaaa gttggttttg ctctctgtcg ctccttggtt
    22261 gcagaaaagc atgatgtttt gctgattgag caagacgaag ctgttctcaa tcatattgtc
    22321 agtcgctttg atatcattgg tatccttggt aacgggggcg attttgccat tcttgagcaa
    22381 gccagcgtcc aagattgtga tatctttatc gccctgactg agcacgatga agtcaacatg
    22441 attgcagcag ttctagccaa gaaaatggga gctaaagaaa ctatcgttcg ggtgcggaac
    22501 cctgaatatt ctaactctta tttcaaggaa aagaatattc tcggtttttc tcttatcgtt
    22561 aatcctgagc tcttggctgc ccgcgctatc gcgaatatca ttgacttccc caacgccctg
    22621 tctgtcgaac gctttgctgg tggacgcgtt agcctcatgg aatttgtcgt caagtccacc
    22681 agcggtcttt gccaaatgcc catttctgat tttcgtaaaa aatttggtaa tgtcattgtc
    22741 tgtgcgatag agagggatca tcaaattatc attccaagcg gtgacatgac tgtacaggat
    22801 aaagatagaa tctttgtcac tggtaaccgt gtcgatatga tactcttcca taattatttt
    22861 aaatcacgcg ccgtgaagag ccttctcatc gttggggcag gtagaattgc ctattatcta
    22921 cttggtattc tcaaagatag tcgtatcgat acaaaagtca ttgaaatcaa tcctgaaatc
    22981 gccagcttct ttagcgagaa attcccaaat ctctacatcg ttcaaggaga tggaaccgca
    23041 aaagatatcc tgctggaaga aagtgctcaa cactatgatg ccgttgcgac tctaacagga
    23101 gtcgatgagg aaaatctgat tacatctatg ttccttgaca gggtaggtgt acagaaaaat
    23161 attactaagg tcaatcgtac cagtctcctc gagattatca atgcgcctga tttttcaagt
    23221 atcatcacac ctaaaagcat cgctgtagat acgattatgc actttattcg tggtcgagtt
    23281 aatgcccagt attcagacct tcaagccatg caccatctag ccaatggcca aattgaaacc
    23341 ctgcaattcc atatcaagga agccaataaa atgactgcca aacctctttc tcaactgaaa
    23401 ttgaaaaaag gggttcttat tgcagccatt attcgaaagg gcaagactat tttcccaact
    23461 ggggaggata tgttggaagt tggagacaag ctcctagtaa caaccttgtt gccaaacatc
    23521 accaagattt atgacttgat tgcgaggtaa gaaatgaata aaagtatgat tcgttacctc
    23581 ctttcaaagt tacttttgat tgaagctgtt ctcctcttgg ttcctgtggc tatcgctgtc
    23641 tattaccgtg aatcgagcca agtctttaca gccctctttt cgaccatagg gattctcgta
    23701 ttgttaggcg gttcagggag tttacagaag ccaaaaaatc aacggattta tgccaaggag
    23761 ggagtcttga tcgttgccct ctgttggatc ctttggtctt tctttggtgg tctccccttt
    23821 gtcttttctg ggcaaatccc tagcgttatt gatgcctttt ttgaaattag ttctgggttt
    23881 acaactactg gagcaagtat tttgaacgac atttcggttc tcagccgttc cctcctcttc
    23941 tggcgaagtt ttacccactt gattggaggg atgggagtgc ttgtttttgc acttgctatt
    24001 atggacaatg ccaaaaatag tcacctagaa gtaatgaagg ctgaggttcc tggtcctgtc
    24061 tttggtaagg ttgtatccaa attaaaaaac actgcccaga tcctctatct cctttacata
    24121 gccctctttt ccctctttgt catcatctat tatctagccg gtatgcctct ctacgatagt
    24181 tttgtcattg ctatggggac agcgggaact ggaggattta ccgtctataa cgatggaatt
    24241 gcccactatg gtagctcact gattacctat ctggttagta taggagtttt ggtttttggg
    24301 gtaaatttca atctctacta ctaccttatg ctccgtcggg ttaaggcctt ctttggagat
    24361 gaagagcttc gggcttactt ggtcatcgtg ctggtttcta caggcttgat taccctcaat
    24421 actctctacc tctacccagg attttccaaa agctttgaaa tggccttctt ccaggtttcc
    24481 aacatcatta caacaactgg ttttggatat ggagatatta ccaactggcc cctcttctcc
    24541 cagtttatcc tcctcttcct catgacaatc ggtggttctg ctggatcaac tgcaggtgga
    24601 ctcaagatta ttcgaggcct catcctttca aaaattgcca aaaatcaaat tttgtccatt
    24661 ctatctcccc accgtgtttt gactctccat gtgaataaaa cggtgattga taaggatacc
    24721 cagcataaaa ttctcaagta ctttgtcatc tatgctatga ttttgctatc ccttatcttt
    24781 attgtcagcc tagatagcaa tgattttctg atcgtgacca gcgctgtctt tagctgtttc
    24841 aataatatcg ggcctattct aggaaccact tctagtttct caatctttag tcctatctca
    24901 aaaattctcc tctcctttgc aatgattgca ggccgcttgg agatttaccc aatcctactt
    24961 ctctttatga agagaacttg gtctaagaga taaaatacaa aatctctctt tttacaatta
    25021 tgaaagaggg attcttatat tatacttcct gcggaacaaa atatggtata gtagttctat
    25081 gaattatgaa gcaagtaaac aactaactga tgcacgattc aagcgtcttg ttggtgttca
    25141 gcgcatgact tttaaagaga tgttagctgt attaaaacag cttatcaact taaacacgca
    25201 aaaggtggac gaaaacctaa attaagccta gaagaccttc ttatggtcac tcttcaatat
    25261 gtgcgagagt atcgaactta tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac
    25321 ttaatccgtc ggagccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca
    25381 agaactcctc tcagttctga ggacacggta atgattgatg cgacggaagt acaaatcaat
    25441 cgccctaaaa aaagaattag cgaatgattc tggtaaaaag aaatttcacg ctatgaaggc
    25501 tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcactg tgaactattg
    25561 tcatgatatg aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt
    25621 ggctgacagt gattatcaag ggctcatgaa gatatatcct caagcacaaa ctccacgtaa
    25681 atccagcaaa ctcaagccgc taacagctga agataaagcc tataaccatg cgctatctaa
    25741 ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgttttcaat
    25801 aacctatcga aatcatcgta aacgcttcgg attacggatg aatttgattg ctgatattat
    25861 caatcatgaa ctaggattct ggttttgcag gaagtctaat atgaaaacaa gacgacttcc
    25921 atataggaaa ccgccttcta gctatgttga gtgatttata ttaaaataac ttttcttcta
    25981 gcttcatttt attattataa aaacattcat cataaccccc agaacttaaa taacgatttt
    26041 tattcaagat acatactcct agaataaact ttatatgaaa tccccatttt tgtttttaca
    26101 attctcctga tactcaatga aaatcaaaga gcaaactagg aagctagctg caggctgctc
    26161 aaaacactgt tttgaggttg tagatagaac tgacgaagtc agtaacatct atacggtaag
    26221 gtgaagctga cgtggtttga atttaatttt cgaagagtat tagttaaatc ttgcttaata
    26281 tatctacacc atactatttt acatatagta tttagcacga cataatactg aagtctctct
    26341 ccaaaaaacg gttatgcctc tttgaatagg aagttctcac aagaaaagca tctccacgtt
    26401 tcaacttcat atggctcaaa aacaatcaat tgatgctaaa acctgtacct agatgtttcg
    26461 gttcataaaa ccatgaaact gtaaaaatgg atgaaattga tagcgggtag tcagatcaag
    26521 agacatcata actctaaaaa gtcacaatat agtagattga agttgaaata gtacactttg
    26581 gtttctaaaa cattattata agttagttta aattccttaa tcaatttgta catttttatt
    26641 tcatttcact atagataagt tcatcctcag aaaaatatca ttctaattgt tgaaatggat
    26701 atataaacag gggtattaac attaaatgct catgaaacaa cgaatacagg tatcaaaact
    26761 gtaacaaaac aagtccctaa atttactaaa gacactgctc aactttacac ctgtaaatgg
    26821 ttgttgtata ataaagttac aaagatgtac gaccacaccg ttgtaaatca tagtgttcgc
    26881 gaatatatta ctgatagcat ttctacaaat acaattgaag aggctagata gggtttaaac
    26941 gaaatatgtc agtgttttag cattcctagc cttcatatca tttaaagaat tgtatagaca
    27001 aaatttttcc caatacagac actcgtaaca actgcttcat ttttctacca acatatttag
    27061 gaacaggata agatacaaga gaattaatcc atagatcagt tctataccaa tctaagataa
    27121 ataagctaaa aaacaattaa taataagcaa atagattcca aattttctct atctgctcat
    27181 tttaataaac aatactagtg taactatcct tccagtcaga agcttgtcaa accacatcga
    27241 aaatttttct aaaatttatc tcgttaggca atcaagcaaa aactcgacga tagtacaaac
    27301 attatcatac aggattgact tcctaaatta tatgctttag taaggttttc ggataagaaa
    27361 aaaggttcat tttacatctc taaacactct tttctaagat gaaaaacaga atttttcgat
    27421 tgtgatttaa agcaacaaga agattttcag tatcatccta tagatacgag ctaattaaga
    27481 aaaactacat ttttgaatat aaactacaat aagataaact aaatttcata ggaggaagac
    27541 aatggattgg tacgattata tgatacaggc atccaaacaa tcacaattca acgcaagcca
    27601 ttggtttcgc tatttgcgaa aagttatttt tgaagactat tcttatttaa caaaccaaga
    27661 tgtaaaaaag ttgctagact ccaaagaact aacccgtttt caaaaaatta gcttgaagta
    27721 tgcctttcaa gagcatactc caactcataa atatgtgatt tcattaaata aacctgctaa
    27781 gttaaccaat gttcaaaaat tgatggagaa atacaaacat ggataaaatg aaaccggtct
    27841 tccaagccct aaataaggaa ttaattcagg aaaatctgac tttaacaatt atctgtgtcg
    27901 gtggttatgt cttagaatat catggtttac ctgccacaca agatgttgat gctttttatg
    27961 accaaaatca gaaaataaat gaaattattg ctcgtgtagg aaaacagttt aatcttaaca
    28021 cccacgaaga gttatggctc aacaatcatg ttgcaaagca aatatgaaca aacaacctcc
    28081 cttaagttta tgcgaatcct tgtagtcatt tgagaatctg accgttttag tagtccctat
    28141 tgagtatgtg ttaggaatga agatgatgag tatcagagag caggatttgc aagatattgg
    28201 tgcaattatt aaatacaaaa actttcattc accattcgat gcctttaaat atttaaaaga
    28261 catgggattt gatactattg acctctctgt tctattagaa ggttttagtt atgcttatgg
    28321 tatggattgg ttagaaaaat tttttaaaga aaatcaagat aaacttcgcg aattttatta
    28381 acagtatcaa acaagatgat tgtcaattag acagtcgtct tgtttttatg atgaaatgaa
    28441 ataagaatag gacaaatcga tcaggacagt caaatcgatt tctaagaatg ttttagaagt
    28501 aaaggtgtac tattctagtt tcaatctatt atatttcaga ttcggtccac tattccttcc
    28561 caaaaacatt gcatattgcg ccgaaggaat tgctcacact atcccaagca caaacccctc
    28621 agtcgattga ccgagggttc ctttttatta ttcaagaact tgattagctc aatgcatcca
    28681 aggcatcatc cattgaaaga acttcgtgga agacacgttg tgtcaattca gttttttgtt
    28741 ctggagtgag gtatttagtg tttacacagt atccagagat acgtacgata acgtcttcgc
    28801 ctgacatgat cttttcgtaa acatcgttca agtccataac gttcaagtta acgtgttgtc
    28861 caccgttttc aaagtaacca tcaaggattg ttaccaagtt atcaacttgt tcatcacgag
    28921 tcttaccaag agcgcgaggt gatacttgtg tagtcaatga gataccgtca gctgcataac
    28981 taaagtcaag gctagaaagt gagttcaagt tttgcaacca accaccttta gctttgttag
    29041 atgggttagc acctggtgag aagaattcaa gtttagacaa gttcacagaa ccatcttcgt
    29101 tgaggtatac acctttgtga actggtgagt taccagtttg tttagagtaa gcaacgttag
    29161 atgtgattgt caaaagtgat actgtagctt ctgcgtcttt gtatagtttg tggctacgta
    29221 gacgagttgt gtaagcttcg atcaaccatt ctgccaattc gtttgaacgt gggtcatctt
    29281 caccccagcg tgggtagtca ccgattgttt cgtaatcgta gatgtagcca tcttcatcac
    29341 ggattggttt aactgtagcg tatttaatcg ctgacaatgt atcaacagtg ttagcaaatc
    29401 cacaaatacc gaatcccatg ttggcacgtt gtttagttgg caagaaggcc atttgaacag
    29461 cttcgtagtt atacttatca gtcatgtagt ggatgatgtt caaggcatct acgtaagtgt
    29521 cagtcaacca gtcaagagat ttttcaaagt tcgctttaac tgattcaaat tcaagaactt
    29581 cgtcacgaat aggatcgatg tcaaatactt tgtagtcttt gtgaacatcg tcgtaaccac
    29641 cattcaaacc agtaagaagg gctttgagaa cgtttacacg agcaccgaag tactggatgt
    29701 tgtggcgttg ttcttcattt tctggatcaa gtggagacac acagcatgag atacagctca
    29761 tttcaccata tccgtcttta gccattgttg ttacaccttc gtattggata gaagagtgtt
    29821 tgtggctcat gtgcatacag tagcgacgga agttgtatgg caatttgtca gtccaaagaa
    29881 ctgtcaagtt tggctctgga gagttaccga tgttgtcaag agtgttcaag aaacggtagt
    29941 ccatcttagt aacacggtga cgaccgtcgt tacccatacc agccatagaa gttgtgatga
    30001 atgttgggtc acctgagtac aattggtcat aagcttttgt acgagcaaat ttaactgtac
    30061 gaagtttcat aacgaaatca tcaacgaatt cttggatttc tgattcagta aatgtaccac
    30121 gagcaaggtc acgttctgca aagatgtcca atacgattgg tacacgacct agagatgtag
    30181 cagcaccgtt aatcacacgg cagacagcca tgaaagcaat gttaacccat tggattgctt
    30241 ctttcacgtt catcgctggt ttgcgaacat caaccccgta aaggtcaccc aggcgaacaa
    30301 cttgttgcaa tgcttggtat tgaaggttta cttcttcacg aagacggatt gtttcttcat
    30361 cgatttcttt gattgcattc cagtcattta ctttttcttg catcaagtag tctgcaccgt
    30421 aaagagcaag acgtgcgtaa acaccgatga tacgtccgcg tgagtatgca tctggaagac
    30481 cagttacagt gtgtgcgtga cgagcgcgac gaatatttga agtgtaggca cggaaaatac
    30541 cgtcgttaac tgttgttaca tatttagtga agatttcgtg aacagctggg tctggttcgt
    30601 atccattttc ttttaaagta gtttcagcca tacggatacc accttttggc atgaagttca
    30661 atttgaagag ttcatcgttt tggataccga agataacttc attttctttg tcgataaatc
    30721 cagcagggat atcagcgata gatgttggac gagtgtccat tgggaaacga gtttcttcgt
    30781 agtgtgcttt agtttcttct acaattttct tgatgtgaag tgaacgctct gttgatcctg
    30841 caaggaagct ttcgtctcca tcataaggtg tgtagttagc ttgtacaaag cgtgatacac
    30901 ttgctttttc tttccaatct acgcctttga agccttccca agctttgtca aaaatatctt
    30961 gtgcttcaac aactgtctta acaaccatat taatgtcctc ttttttctag taacagtcat
    31021 ctgttacatt catgagacaa gtataccata tagtaaccgt tttcaacaag tgaaaaatcc
    31081 ctatttttac actttctttt ctaaaacagt ctatatttta tttcaaactg tattatattt
    31141 ttgaaaaaat aaagtccttt tttctttttt tcagaaaaaa gggtataata aaagaaaata
    31201 agcagtaaca ctcaatggaa atcgaaaagc aaactaggaa gctagccgca gattgctcaa
    31261 aacactgttt tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat
    31321 aaaaaggtgc taggcatgtt gatttttcct ttgttaaatg atttgtcaag aaaaatcatc
    31381 catattgaca tggatgcctt ttttgctgca gtggaaatca gggataatcc taaactcaga
    31441 ggaaaacctg tcattattgg aagcgaccct cggcaaacag gtggacgggg agtcgtttct
    31501 acctgtagtt atgaggcaag agcttttggt gtccattctg ccatgagttc caaggaagct
    31561 tatgaacgtt gtccccaggc tgtctttatc tcagggaatt atgagaaata caagtctgtg
    31621 ggactccaga ttcgagctat ttttaagcgc tatacagatt tgattgaact catgagcatt
    31681 gacgaagcct atttggatgt gacagaaaat aaactcggta tcaagtcagc ggtcaaaatt
    31741 gctcgcctca ttcaaaaaga tatctggcaa gaactccatc taactgcttc cgcaggcgtt
    31801 tcttacaaca aattcttagc taaaatggcg agtgattatc aaaagccaca tggtttgaca
    31861 gtgattctac ctgaacaggc tgaggatttt ctcaaacaaa tggatatttc caaatttcat
    31921 ggagtaggaa aaaagacagt agaacgtctt catcaaatgg gcgtttttac tggtgctgat
    31981 ttacttgaag ttcctgaggt aaccctaata gaccgttttg gtagactagg ctatgatctg
    32041 tatcgaaagg ctcgtggcat tcacaactct ccagtcaaat ccaatcgcat ccgtaaatca
    32101 atcggcaagg agaaaaccta cgggaagatt ctccgtgccg aggaagatat caaaaaagag
    32161 ctgactcttc tatcagaaaa agtcgttctc aatctacatc aacaagaaaa agctggaaaa
    32221 attgtcattt tgaaaatccg ctacgaggac ttttcaactc ttaccaaacg aaaaagtctt
    32281 gctcaaaaaa cacaagatgc tagtcagata agccaaatag ccctgcaact ctatgaagaa
    32341 ttaagtgaga aagaaagagg tgtccgccta ttggggatta ccatgactgg attttaaagc
    32401 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgctcaaa acactgtttt
    32461 gaggttgcag ataaagctga cgcggtttga agagattttc taagagtata aaaccttgaa
    32521 gagttgcccc ttcaaggttt ttcttataca aataaacgga caaaactgta aagtagcaaa
    32581 acactaccaa gcacgatacg gtatttacca aaaagggtga agtcgtgttt tttcacatag
    32641 ctggtcaaga agcgaatagc caccatgctg accgcaaaag ctactcccat cgcgaccaag
    32701 agcaaaaaca attgcccaaa gctcaagagt tctccggctt tcacaaattt gaaaatcttt
    32761 aaggcactag ctccaaacat aacaggaatc ccaagataga aggtaaattc tgtcacaact
    32821 gaacgactgg ttccatttaa caaaccaccg acaatcgttg cacctgaacg gctagtccct
    32881 ggtaaaagag caagaacttg gaagagtccg atatagaaag cggtcgtata aggaagcttg
    32941 tccaactctg ttacacttgg ctcgatagca cgcgctttat tgcgcttttc caaatagatg
    33001 aaggcaaccc cgtagataat caacatgaga gcaactgaaa ccatgttatg gaagtgggta
    33061 tcaaaccaat catcaaattt aaagacacca agtaaaggta aagtagcaat caagaccttc
    33121 aaccatagtc tccaagtctt acgaacttcc tgtttgtcct tagtcggttt aaaaggattg
    33181 agcttgttaa aataaatcac cataactgct aagatagcac caagctgaat cacgacatta
    33241 aacatggaca taaaggcttc attttgattt tggtattgga taaactcctc tgctaaaatc
    33301 aagtgacctg tactggaaat cggcaaccat tccgtaattc cttcaacaat cccgaagaag
    33361 atagatttta aaatttcaat aagatacata gattactccc tatattatat ttagcgcagt
    33421 tagctactgc caaagcccaa gtggtatact tggaataagc cactgtggat tagttcattt
    33481 cctccaatcg cttgacgatt tccgaaaggc tctaaccaca gcttttgttt caattggtaa
    33541 tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg
    33601 gataaccaag tagacttgaa atactatatc tggaggtact cccatgcttt atgtgggcat
    33661 tgatgtcgct aaaaataaac acgatgttac agccttgaat gttccaggaa aaactgttct
    33721 taaaccactc actttttcaa ataataaagc tggttttgaa ctcttagatc tgtctcttcg
    33781 acagctcaac caagactgtc tcatcgctct tgaagatact ggacattatg cctttaatct
    33841 actgaacttc ctgcatgaac aaggatatga agtttacacc tacactcctt tgctcatcaa
    33901 ggaatttgcc aaatcattat cacttcgcaa gactaaaacg gataagaaag acgctcatgg
    33961 catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca
    34021 agtagaacta aaaatactgg ctagacatat tcatcgtctc aagaaaaaac agtctgattg
    34081 gaaagtacaa tacactcgtt gtcttgatat catctttcct gagttggata aaatcgttgg
    34141 aaagcattca gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggat
    34201 tgaggcagga tttgataagc tgatagaaat taagcgattg accgcttcta aaattcagga
    34261 tatcctctca gtcgcacctc gttctatcgg aacaacatct cctgctcgtg aattcgaaat
    34321 catcaaacat tacaagaggc tcattgacaa ggtggaaaaa tgtgtcaatg acttgatggc
    34381 tgagttcaac tcggtcatca cgacggtcac tgggattgat aatcgtttag gggcggtcat
    34441 tttagccgag attcgaaata ttcatgcctt tgataatcct gctcaattac aagctttcgc
    34501 tggactggat tcttctattt atcagtcagg tcagattgat ttagctggaa gaatgatcaa
    34561 acggggttcc cctcatctgc ggtaggcact catacaagct gccaaagcat gcgctcgctt
    34621 ttcacctgct tttaaggcct atcttaagac taagttagaa taaggaaaac attacaatgt
    34681 agccatcatc caccttgcaa aaaaacttat ccgaaccctg ttttatatcc taaaaaagag
    34741 ctgccatttg acgaacaaaa agtgatgtaa tttctgaaat taacacagga ttacctttga
    34801 aaaaatggac tttttcaagg gctttttgcc gtgctctaaa atcatcgcca aatcatcaaa
    34861 ttgaaataag aaatagttta gataaaacta ttgacttttc ttatagtttg tcttttttct
    34921 atcttccatt atatcatact ttttcagtct atggtagctc tctttaaaag gcaccgatac
    34981 tgccgccacc tccgcctcca gagaagccac caccagaact tccacttcca gaagatacag
    35041 agtaggtgct tgctgtattt gcgacactag cataatgact catttgtgct gttgaatgat
    35101 aaaacatact gtgccagcca taagctacat agaaattgat atctggattt tccacttgaa
    35161 tctgatgaac cttcatcaaa tgactaacct tgtccgcata gccaaataag gtcgcataga
    35221 ccaagaggcg attccagacc acaatacttt ccagttcagc ctgatccaat cgtgcaatct
    35281 cacgcaacat attttcaaaa ctggtccaga gatagtagac ctcagctccc gcttcattta
    35341 gaacaccatc acgattatct agttgaagct tccaataata gagaacagac aaaactaacc
    35401 ctagaaaacc aagtattggc aaggggaggt aaagatagcc atgaacgtct aaactgtaca
    35461 agaacaaacc aaatccgata aataggggca agatagtcaa gacacccata cccacttgca
    35521 aagccttttc cccaccagtt aaaggacgat agtaatctgg gagtccccag aagacaactc
    35581 gctttctcac tccttcttgc atctctttta atactgcttc gaaagaagat ttgagctgaa
    35641 tccctcttgc ttgaatccgt ttttcatcag aaactttggc tctacgataa agactatcag
    35701 ataccttgta atccgcaaac aaattggaaa gagtttcttc ttttttacct gaaaaagcta
    35761 gatgtaggca gtctttctca aagcttgaca aaccatcttc ttttactagc ctcaaaccaa
    35821 ctgcatctcc ttctgaaata atagaaacat tcccacggtc catcacatct agcaaggtag
    35881 cttgaataag ttggtcaaaa gtgaatttgc cagccccctt gactaaggga ctcacttcct
    35941 ccaaggaggt cgagtagaca gcctctgata aaaccatagg ctctaattcc attggcggtt
    36001 cgtagagacg atgattttta gcatatttga ttgaaggagc ggtttttctt ctatagataa
    36061 aatagaaaca gatgctcaat aacaaggaga tggaaaggat cgaagggaag atccaagtaa
    36121 gtagttgttt actttgctct ttttctttaa caatcgaatc ctctatctta ttaaactctt
    36181 ctaaacgatt ccctttcaag ccctgatccc tagcgctagc aaaatcagtt cgaggccagt
    36241 aggcatgcaa ctcagctcca cgcttagccg gaagattgtc taaacgaata gtataatcaa
    36301 ggttactctt ttcaaccgtt ctctctctaa aaagtttccc tgtatggaaa aagagtttct
    36361 cagccccctt gtctcccctt acatgaaatt caaacttttc aatagactct gaactatctg
    36421 tcagaggttg ccaatttaat tcagcgatat catcataaag gaaaagtaaa ttttttaagt
    36481 tccagacgag atcaacttca actatgtcgc cctcctgacc tggattatag actctcacag
    36541 tataaccatc cgcttcttct gttacttcgc tagtcacatc tgctagttct gcaccgtttt
    36601 tcgcggcctg aacctttgta tgagggtcaa tgtcaaaccc gctaggcatc ttgccagcac
    36661 gtccaagtcc cacgatttgg cccttaaagt cctcctcaaa ctggtaaact atcttctgtc
    36721 taaactctgc cgtattatct gcatgaatat acaaatcccc ttgataagag tttatcttga
    36781 aatcaatggc aaaaacagag agtggaagaa ggcaaaacaa gcctaacacc agtaagaaaa
    36841 aagttttttt catcaactaa gccccctttt tatctttctt atcattatag cattttttcg
    36901 taagcaaagg cttacttatg ttgaaaaatt acgcattttt cgataaaata ggagacagtt
    36961 attttttaat agattagaaa taggagaaat tatgagaaaa atatacttat ctattttcac
    37021 aagtctcttg ctgatgctag gacttgtcaa tgttgctcaa gccgatgaat atttacgcat
    37081 cgggatggaa gcagcatatg ctccctttaa ctggacccag gatgatgata gcaacggagc
    37141 tgtcaaaatc gatgggacca atcagtatgc caacggatac gatgttcaaa tcgccaagaa
    37201 aatcgctaag gacttaggta aagaaccttt ggttgttaaa accaagtggg aaggtctagt
    37261 ccctgccctt acttctggta agattgacat gattatcgca ggtatgagtc caactgcaga
    37321 acgcaaacaa gaaattgcct tttcgagcag ttactacact agcgaaccag ttctactggt
    37381 caaaaaagat tctgcctatg caagtgctaa atctttggat gactttaacg gtgcaaaaat
    37441 cacttctcaa caaggggtct acctctacga cttgattgca caaatcccag gtgctaaaaa
    37501 agaaacagcc atgggagact tcgctcaaat gcgccaagct cttgaggctg gtgtcattga
    37561 tgcttatgtt tctgaacgtc cagaagcact gactgctgaa gctgcgaact ctaagttcaa
    37621 gatgattcaa gtagaacctg gtttcaaaac tggggaagaa gatacagcta tcgctatcgg
    37681 gcttcgtaaa aatgacaatc gtattagcca aatcaatgcc agcattgaaa ccatttcaaa
    37741 ggacgaccaa gttgccctga tggatcgtat gatcaaggaa caacctgccg aagctacaac
    37801 aactgaagag actagcagta gtttctttag ccaagttgct aaaattcttt ctgaaaactg
    37861 gcaacaactc ttgcgtggtg ctggtatcac tcttttaatc tctatcgtcg gaaccatcac
    37921 aggtctcatt attggacttg ctattggtgt tttccgtact gctcctctct ctgaaaacaa
    37981 agtcatttac agcctacaaa aactagtcgg ctggatcctc aacgtctaca ttgaaatttt
    38041 ccgtggtacg ccaatgattg ttcaatcgat ggttatctac tatggaactg cccaagcttt
    38101 cggtatcaac cttgaccgta cactagctgc tatcttcatc gtttcaatca ataccggtgc
    38161 ctacatgact gaaatcgtcc gtggtggtat cctggcagtt gacaagggac aatttgaagc
    38221 tgcgactgct cttggtatga ctcataacca aaccatgggt aagattgtcc tacctcaggt
    38281 tgtccgcaat atcctaccag caactggtaa tgaatttgtc atcaatatca aagatacatc
    38341 tgtattgaac gttatctctg ttgtcgagct ttatttctca ggaaataccg tggcgacgca
    38401 aacctatcaa tacttccaga catttacaat catcgccgtg atttactttg tcctcacctt
    38461 caccgtaaca cgtatcctac actttatcga gcgcagaatg gacatggata cctatactac
    38521 aggtgctaac caaatgcaaa cggaggattt gaaataatga cacaagtaat ccttgaaatt
    38581 aaacacctca aaaaatccta tggacaaaac gaagtgctaa aagacatttc tctcactgtc
    38641 cacaagggag aagttatctc tatcatcgga agctctggaa gtgggaaatc gaccttccta
    38701 cgctccatta acctacttga aacgccaact gatggacaaa tcctttatca tggacaaaac
    38761 gtcctcgaaa aaggctatga cctcacgcaa taccgtgaaa agttagggat ggttttccaa
    38821 tcctttaacc tctttgaaaa tctcaacgtt cttgaaaaca caatcgtcgc tcagacaact
    38881 gtccttaaac gcgaacgcac agaagctgaa gaaattgcca aagaaaacct ggaaaaggtc
    38941 ggcatgggag aacgctactg gcaagccaaa ccaaaacaac tctcaggtgg tcaaaaacaa
    39001 cgtgtggcca tcgctcgtgc cctctccatg aatccggacg ctattctctt tgatgaacca
    39061 acatcagctc tcgatccaga aatggttgga gaagtcctca aaatcatgca ggacctggct
    39121 caggaaggct tgaccatgat tgtcgtaacc catgaaatgg aatttgcccg tgatgtctct
    39181 caccgtgtta tctttatgga taagggcgtg atcgctgaag aaggtaaacc agaagacctc
    39241 ttcaccaatc ctaaagaaga ccgaacaaaa gagttccttc aacgctatct caaataaaaa
    39301 gaaaaggctg catcaaccgt gcagtctttt tgctgtcctc aaaatgaaaa ggcagattct
    39361 ctatctctac tacttgaagg tcaagaatcc gccgttatcc aaagattaat cttcaaattt
    39421 ttcataattt ttttcataga aatcaattag gcctagggct gtttcaaatg aaatattttt
    39481 tacttttgca cgaccctgcg ccagagcaat gatagacatt tcacgcgcat tcgtttcttt
    39541 agagatacgg tagcctgtga ttttcttatc acgaacccag ccaacaactg attctacttt
    39601 ttcaaagttt gacttagcca tgtttttctc ctattttctt ctttataata tttaattgta
    39661 tacgttttta ctacttttgt caataaaaaa aacatatatt caacgaaaat aattagttca
    39721 gaattttctt acttcctttt taaacccgat aatatatagg ttttgctagc ctctacacca
    39781 taaatatttg ctaataaaaa tactgtatta ttaccctctt aaggtgcgaa attattcaag
    39841 ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt taagaactga
    39901 agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac tcctatcttt
    39961 cttcctcaat aaatcatctg agagataggt attccttata tccttcaaat tcatcactcc
    40021 tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc atccttaata
    40081 gagatgacaa gacagataag ctcagttaat tacttatata tctttttaat atggtatatt
    40141 tgtcaacaaa aagaaatcaa atcatacctt atactcaatg aaaatcaaag agcaaactag
    40201 gaagctagcc gcaagttgct caaaacactg ttttgaggtt gcagatagag ctaacgtggt
    40261 ttgaagagat tttcgaagag tattaaagac agtgtgacta tgcttgtcaa tagataggaa
    40321 atcaaaatga aggatggaaa tctgagccaa acatcataaa tgctataatg aacagaagta
    40381 agaattgcac gataagcttc ctaaaaccat aggaatcgct ccctttcttc atcttcatta
    40441 tagcacctat acatcagttg tgcaaataat atgatatttt tttattagtc ctcagacaag
    40501 catattataa agcgtttcat taccatttaa gttaatataa gctggatcaa aaccttccat
    40561 tctacggatc aaacctgcat aatcatgctt atctgccaaa gcgatcccaa tcaatactgg
    40621 gcctgttccc ttgctagctc gtttgatata ctcaaaacgt gtgatatcgt catttggacc
    40681 cagaatatca tttacaaact cacgcaaagc acctggacgc tgtggaaaat tgaccacaaa
    40741 gtaatgcttg atgccatcat aaatcaaggc acgctcttcc atttctggca tacggttgat
    40801 atcattattt cctccagaaa tgatacaaca aatggttttc cccttaatat attcagccaa
    40861 aacctctaaa gaggcgatac tagccgctcc agcaggttct gcgacaatcc cttgcttaga
    40921 gtagaggtca atcaaagttt cagaaatcag cccctcatca acacctacta aagtttgaac
    40981 atgttgacga gttgcctcat aggtcaactg acctaccttt tgcacagcaa tcccatccgc
    41041 aaatttatca atttccttga gtttgactgg acctccagcc tcaaaggcag ctttcatgga
    41101 acgcgctcca ttcgcctcta ctccgataat ctcaatctct ggacttgttt ccttgatata
    41161 ggtagaaatc ccggcaatga gaccgccacc accaacagga accaagacag catcaaaatc
    41221 aatcgattct tttcgagctt cttctaaaat ctcataagca actgttcctt gacctgcttg
    41281 aacatgagca tcatcaaaag gatcaataaa ggtacgattc tcagagactg taaattcttg
    41341 agctgctttg gctgaggcat caaaggtatc tccaactagt ttaatagtta caaaatcccc
    41401 accaaaaaag cgaacttgac caattttttg ttgtggcgta gtaatgggca taaagatagt
    41461 agcaggaatt ttcatctcat tacaagtata ggcaactccc tgcgcatgat ttcccgcaga
    41521 ggcacagact accccacgct cacgctcttc cttgctgagc tgagaaatag cataataggc
    41581 accacgaatt ttaaaagagc gaacacgttg agcattttcc tttttcaaat aaatcttagc
    41641 accatacttc tccgataaat aatgatcgta atccagtgga gtattcacaa ccacaccgtt
    41701 caagaccttg tgagccttga ttatatcttt tgaacttaac atataaaacc tctttttcta
    41761 taaaaaacag tcactaatga ctgtttttta gttattcatc tccgaaaact tcagtaacac
    41821 tttcatggta tttatgagcc atacgaatcg aaaactcttt aggaagttca taacgatttg
    41881 tggaaatcca atcatataac cattctacca aactttcttc actatcatta cgaaagtttt
    41941 cgcagtccag tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg
    42001 atataaaccg ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa
    42061 agcttctccg aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa
    42121 tgttttttat ttctcaaaat ccatttcgct atataacgag cagatttagt cgcaccagct
    42181 ctctcaaacg gagaatgaat ttcaagacct tcttctctag atatttgtgc caatttgaag
    42241 aattgttcaa agttcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta
    42301 attacagcat tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc
    42361 gacggtgtaa ttacattata caactagaac caataataac gatgcaattt ttctcataat
    42421 ctttttcata aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc
    42481 atcatcgtcg tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc
    42541 aatttcaagg ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata
    42601 gtcatttaca aagtcatttg caaatttacc attttggatg tctgccaaga cagccttcat
    42661 attttcttta acttgttcag tgattacacg tagacctgat acatagtcac cgtattcagc
    42721 agtgtttgaa atagattgac gcattttctt gaatccacct tcgtagatca agtcaacgat
    42781 caatttcatt tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt
    42841 caagacttcg aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc
    42901 accaaacaaa tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc
    42961 cgctccaaca cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg
    43021 atatactgca taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg
    43081 tcctggtcct ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc
    43141 aaagtggatg ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc
    43201 gatttctgct tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc
    43261 agccaactta gtagcttctg ctactatgta agtatcaaat ccatcttctt ttgctttatc
    43321 aaaagattta cctggacgta caccgataat aacgtcacga cctgaatcac gcaagttttg
    43381 agcatgcgca tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc
    43441 tgctacttta acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct
    43501 attatttatt gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta
    43561 aatccagttg cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat
    43621 agggcttcgc tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg
    43681 tctaccactg ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct
    43741 ggcgctgaca tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct
    43801 cgaatgcgaa tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca
    43861 tgagaagcaa catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca
    43921 acagagatgc tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagg
    43981 actcctgaac gattttgtag ttttgctgtt aacattctac gcatggaact gcacccccaa
    44041 catctcatga ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat
    44101 atctacctca attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt
    44161 ctcaggattg tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc
    44221 aggaagggta tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg
    44281 gcgaaccatt ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat
    44341 attcaaaata gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac
    44401 tacctcctta tctgggttag caattttagc accgattgct gctggaattc caaatcccat
    44461 tgttcccaaa ccacctgaag tcactaactg acgttcattt tggtagggat aatactgagc
    44521 tgtccacatt tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc
    44581 accaattcgt tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg
    44641 aacacgattc ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt
    44701 tggttctgct agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc
    44761 actgataatc ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt
    44821 agcgaaagtc ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat
    44881 aaagtccgct tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc
    44941 aagaaagagt gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg
    45001 aatttgatag cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc
    45061 accaccagct aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat
    45121 ttgcatatca ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata
    45181 aatgaagtct gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg
    45241 acggcctgta gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc
    45301 acgaacttgg taattgtact tagtgattgg catggtaatt cccacgatgt ctgcctcctg
    45361 aaaggcatcc ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac
    45421 gctatcgctc atggcatccg caatccctgt aatggcattt gttgctcctg gtccactagt
    45481 gacgacggca acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca
    45541 accttgctca tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata
    45601 aaaaggcaaa accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag
    45661 tgtttccaaa actaggtccg accccgtctt aggagattct aaactgattt tctccattat
    45721 tcccctttct ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt
    45781 caagataaaa gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt
    45841 tttgttttta ttaaaaagat accgatttca tttactaaaa agaaaaaaga actgatttct
    45901 cagtccttca ttaatcttat tccacactaa ataggtatgg gtaaacaggt tgttgacctt
    45961 ggtgaatctc gacttcaacg tcttcgaatt cttctacgat ttcttgagcg atttcattgg
    46021 caagttcttc gcttccgtct tcaccgacat agaaggttac gatttcacta tcttcatcca
    46081 acatatgttt caaggtttca gtcaatgttt ggtgcatatc agggtttgac acaagaattt
    46141 ttccatccac catacctaga ttatcgtttt catggatttc taagccatcg atcgttgtat
    46201 cacgcacggc tgttgtgacg cttccgctaa cgacatcgct aagagcagct gtcatacgct
    46261 cttggttttc ttcaatggac ttgcttggat caaaggcaag aagacttgtc ataccttgag
    46321 gaagagtgcg agcctctacc actactgctg gttgctccaa aacttctgcc gcagattgag
    46381 ctgccatgaa gatgttcttg ttgtttggca agaagatgat gttacgggca ttgacctgtt
    46441 caacagcctt gataaagtct tctgttgaag ggttcatggt ttgaccgcct tcgataacat
    46501 aatccacgcc ttgagaacag aagatatctg ctagaccttt accagccacc acagcaatca
    46561 aagcatactc tttttcttca gccgacttga taacttgagt agcttctttc tcaacctgtg
    46621 cttcgtgttg gttacgcata ttgtcaactt ttaccttgac caagctacca tatttgagac
    46681 cttcttgcat aacaagtcct ggatcttctg tatgaacatg gactttgaca atttcatcat
    46741 cgttaacaac gaggagagaa tccccaagct catccaagta gttacggaat tcatcgtagt
    46801 caaaatcttt agcataggtt ggaccttgct taagagctac catgatttca gtacagtaac
    46861 caaacgtgat gtcctcagtt gctacgtgac cagctacaga cttatgatgc tctacattga
    46921 tcatctcact catgttggca ggagtcgcta caaagtcctc agatgcaata tattcgccag
    46981 taagggctga aaggaaacct tcgtagatga agaccaatcc ttgaccacct gagtccacaa
    47041 cgccaacttc tttcaatact ggaagcatgt ctggtgtttt agctagagct gttttagcac
    47101 cttccaaggc tgcgcgcatg acttcaacag tgtcatctgt ttgctcagct tttttcttag
    47161 caccgatagc agctccacga gaaactgtca aaatcgttcc ttcaacaggt ttcatcactg
    47221 ccttataggc aacttccaca cctgattgga aggccagagc caagtcttga cctgttaact
    47281 cgtctttatc cttgatagct tgggaaaatc cacggaaaag ctgagacgta atcactcctg
    47341 agttcccacg cgcacccatc aaaagccctt tggcaagaat gctcgctact tctccaactg
    47401 tagaagctgg cttgtctgca acttctttag caccattttc aatggtcatt cccatatttg
    47461 tcccagtatc tccatctgga actggaaaga cgtttaatga attgacatat tcagcttgct
    47521 tattcaagcg agttgatgca gcctgcacca tttcttgaaa taagctagta gtaatttttg
    47581 acacggttat tctcctacaa ctttgatatt ttgaatgtag acatttacag tctgagcagt
    47641 aattccaagc tggttttcca agctaaaggc aacacgctct tgaatgtttt ttgacacttc
    47701 actaatcttt gttccgtagc ttaacacggt atatacatca actgcaatac tgccatcttc
    47761 ggctgccttt acgacgacac ctttagaata attttcctta cctagcaggg cttggaaatt
    47821 atctttgagg gcatttttac tagccatacc gaccacacca aaaatctcag ttgctgctcc
    47881 acctacgacg gttgcaatca cttcatctgt tagttcgatt tgaccatctt ttgtattaat
    47941 ttttacagtc atccttttta cctcaactag ttgatactct attttatcat atttcagccc
    48001 aagtgtaaaa gcagaatgat gtatcagcgg atatttactc tatttttcaa atgatgttat
    48061 acccacaata aaagaaaaaa gaccctaagg tctcctttgc ttttattatt aaacgcgttc
    48121 aactttacct gatttcaaag cacgagctga agcccaaact tttttaggtt taccatcgat
    48181 aagaacagta actttttgaa ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg
    48241 tgaacggttg t
//
LOCUS       DAVFJR010000011        44106 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVFJR010000011 DAVFJR010000000
VERSION     DAVFJR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.011"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..2669)
                     /locus_tag="VU722_000841"
     CDS             complement(<1..2669)
                     /locus_tag="VU722_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1771851.1"
                     /translation="MDQEKGRPKTIGHRLDRKLEKVRKNYRTVQQDSAKQLTKLQSQT
                     HSKRQLVKKSRSQFRASKNKVKKIQKEYKRIQKEYKNIQKQGRNLGKEGKSLRPEEIK
                     KQVFLKQELDRNNKKRVFLKQELDKAKLEKKTSKRTFKVAQEANGGSRKKKFLRAAKQ
                     SVERVANQQASSVAHQDDTLSDIARTKYRYQDIQIQGKRIKTIGKYSGKLGQGMVKSS
                     YSLGNRVYNKAKGRGFTQTPREFSWEGKLSRRIQDYKKRLATSKTGKVAKKARKFYRV
                     GSKPLKVIIKNPFSLKAYLIAFGLLLFLAILGIGSSGITRQDEFDMNDTWLYLSKLDR
                     EKSNDKVDYWTKIDDPLLYLNYKYDDISDKLRIDGNNYFSQQNRGKLYLDTLWKNLNG
                     DKDNLKTMEELYTKNNLYKLDKDELEEYKELLEIARDSGKYMLLQELDNPFYTEEQPE
                     SQAPLQIIERFGYKSKTEVFNGSVLQVSGGQSLLAVLDGKVEVKGSDIEISDQDSKFL
                     YKNVDTIRYKTGDHVKAGDIIGKVAPEGNQTVYYQKLEPDRLNKKDKDGNVEKSWTYV
                     NVGFYFQRVEYTQATSVVSNIETSGEKGRRARAFADAIKKNIPEATDEGIAAVLGGFD
                     IESSITFKRYETDYLTNNQFDKVAKEPTAENLVGNWGAFQAMYPTLPLNERGYLVNGL
                     HYIGIGIGQFTGPRALALWNFAKSVNGDIWSAEVQTKFLLEEDDPTRRAAFRRIVTST
                     GSVEALAEDFLNAWLGVPGNKLLERQNAARQWLNFLKNKGGGSTGVSSKQVPAEYKDK
                     LPYGLPTDQALLEGQGYSGNAYELGNCTWYVYNRFAQIGVGIHPYLGNANQWVDSGQA
                     QGYDISTTPKPGSAAVFMNGVAGASPIYGHVAF"
     gene            complement(2680..5043)
                     /locus_tag="VU722_000842"
     CDS             complement(2680..5043)
                     /locus_tag="VU722_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEU1771852.1"
                     /translation="MSLFKSKREKLEKAEKKKIDRLRRQMKPTTQNTINYTLLHEDGL
                     MHIAREKYSRSFMLGDASYSTAQQDEKESIIDTTMDALNSLDEGSNYQLLVINRRVSD
                     NSLQNILYEETNDGFDDYREELNEMIKERFTTHANNFEVHKYVTISTNADDRKQAQLI
                     LQDIGVSLGTQFQESDITFRDMNGLDRLKVFSELLRDNPYVNFDYKEIALTGLFTKSF
                     IAPNRIEFQEKRMIIDDRWCKVLYARRYPNWMSDRLIRDLTTLGLELAITIHAEPYEN
                     VEILEKIDDAETDAEIGKLRSKRKAAQSGIFDDAVVAGRDQEISEATKKWRDEITEYD
                     QKIFSGLIAVYFKADNQEELQRNEQKIKRAGRKLGVEFEDLYYYQEEALNTVLPIGEC
                     FLNVKKNFMRKMTTANIATQVPFTNVDLKSESSLARYYGQNQLSNNIITLDRKRDLNT
                     GSGVVLGSSGSGKSTTIKGGEVIPTLLKYPEDRVIIVDPEDEYSDIGRAFGAQMVDIS
                     IGSKTHINLLDLPDLDRLDDEDDDPIGDKANLLMGLFESILSEVTDAQIGIIDRVTGV
                     TYERYLTENFTPTLKEWHQVLKEQPEPEAQDLALAVETYTTGSQDIFAHNTNVDLNHR
                     FVIFNLKKLSHKLKPFALMVIQDYIWNQIVENQGKCTTWVYFDEMQILFKNKAQADFF
                     TTLYSRIRKYGAIPTGITQNVETLAAVEEGRKLLSNSEFMILLKQKPQDLAILKEIVN
                     LTDKQIRYLARPKAKGTGLIVAGPVVVPFENPIPKNTKLYNLVATDA"
     gene            complement(4985..5359)
                     /locus_tag="VU722_000843"
     CDS             complement(4985..5359)
                     /locus_tag="VU722_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771853.1"
                     /translation="MKKIGSEFLREFETEDKPILFGLTSRMLVLYLCLIIAVSGTTAS
                     YFFGLPDWYIYLWDALFVVPGGMYGTGMTKRMRIKEKINFFFRIQQRTYEIEFGKVGM
                     YTKDEFIQKQKRKTRKSRKEKN"
     gene            complement(5458..5961)
                     /locus_tag="VU722_000844"
     CDS             complement(5458..5961)
                     /locus_tag="VU722_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771854.1"
                     /translation="METLKEIGNKQFNDLQKKHGTRELKDKITSLEQEITRLSWFAYE
                     HELLSEPLLEWILDGKVKISEIPRAVRMSSYGDELYIYAWRYAEAKQDAFYGMRILTL
                     LQEDITYCAIADSISQTEYVYRLEQWIKYMDRGKMVFKGDENFERYFQEQKTANRSLF
                     DTEGVGI"
     gene            complement(6049..6798)
                     /locus_tag="VU722_000845"
     CDS             complement(6049..6798)
                     /locus_tag="VU722_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU1771855.1"
                     /translation="MNLDIRELTSSLSSYGSATNQAVNMMADAVRPIGYILLGLFFWF
                     EMASWSQMVKSRGGSLTQKIWLEALMKYLFAFIMISASSQICDAILELLNIIVKVIAH
                     VTPTVKATIDSNISGGKGIVEKTIITFVGKAVSGVANVILGIIVFLRYLDLYMLKALA
                     PLLVAFFMMDSLRSVTINFLKYFAASALIGVILIIVSVVYDSIVAADILKVTTGSSDS
                     WGTAFASIAKGVIYIFVMVGSSRKAKQLLGV"
     gene            complement(6808..7035)
                     /locus_tag="VU722_000846"
     CDS             complement(6808..7035)
                     /locus_tag="VU722_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771856.1"
                     /translation="MEIITKIITGLGVVGTITGLIWIWNGAVDYIQGRKNKDKQRQDD
                     GSDSMINGAFLAVASAGIAAAVVAALSQLKF"
     gene            complement(7118..7537)
                     /locus_tag="VU722_000847"
     CDS             complement(7118..7537)
                     /locus_tag="VU722_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771857.1"
                     /translation="MKFGSDFSWLWVAIIRIFTAPFYIVLWCINVVKSTIGMFILWVI
                     AKICITIVLIGGMAIIHHLFNFPSENIIDNIFGWYTPHILGMSHDSLITAGQVVDAPK
                     GGGLFFPYPNFEVPIIIGLSILVATVRTIYREEFEEL"
     gene            complement(7609..12054)
                     /locus_tag="VU722_000848"
     CDS             complement(7609..12054)
                     /locus_tag="VU722_000848"
                     /inference="COORDINATES: protein motif:HMM:TIGR04228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1771858.1"
                     /translation="MNRINQKNASIRAENEKNQRENQAEIDRINQENAEIRKRNEAKR
                     GAYESSLTDYTKKLATIKAERDAIQTSKPLFGSETGFKVYGGYNSAGRGSLDYYNDFT
                     VVPDDNLPVESMRGFLGYHADTYVTGGAGTRVSKDSTETYDIIKSPTFGDTFYIHNIG
                     TLTDGRKIMAKVMVSDLGDYQGEVRNGVPVTDSDIYLKGGDGGSFYFVYNNHTRLEMV
                     FDFYIEGTTTPVSLLIGTVITDVDWGQGSNLSYGSSGRGMVLNPSGSGLDFDGRVMKG
                     VENGVNDTSDIPKASFASVGYGSSLTYLHTSSPGSTEGRTPAEWDAENLSGNVQNVVF
                     TILGEGAELKSIPPVNPPRKPTYEVETTPPNSPTGKPEEVLPPKPEEIKEKEIPSLVS
                     PPTVRVRYARLQAMPDLEKFVKNSSGESIDKSYVPKLSTVQWELTTKPLPANREAITD
                     FEIVDALPSGFVLDVEASKKISSDFELTYDESSHVVRMKGLESLKSKLNQDLSKEVQV
                     PAPILVGKVTNDGATYKNNFQLKINNKYASYSNIVQISTPGKPNDPDNPNNNFIQPLK
                     HNYNKDKVIIDGKPVLVGSTNYYHITLDYDQYKGMKADSSTILKGFGAIDDYPEEAVT
                     INQSDIRYIDSEGKEVAGISVYQYDSIDAVDNDKVKAFLASSEIKPKGAFQVFLVDDP
                     EAYFNQYIKSGKSVTIIDPMVTKEELRNTGKSFENTAYQVDFGNGYQTDTVVNNVPTV
                     KPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDDYPE
                     EAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQESLESSHFTPKGAIQVFEA
                     ENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSGYQTDKVENNV
                     PTAKPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDD
                     YPEEAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQEALKSSHFTPKGAIQV
                     FEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSAYITDTVV
                     NNVPTVKPTKKNLNKAGVNIDGKQVLADSVNYYKVTADYSQYKGIEADKDRIGKGFYI
                     VDDYPEEAVTINQDGVQVTDSKGQVVKDLKMSLYESLAKAPSGVQEALKSSHFTPKGA
                     IQVFEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQIDFGMDYVTE
                     TVVNNVPKIEPKKDVVIDHLSKESLDGKEVKLNQTFNYKLVGSLVPKDRSEQLFEYKF
                     SDDYDETHDDYQSVYKVFAAVDFETSDGQKFKAGDELTKFTSQVVDKAKGKVDISFDD
                     ALLKSILETSEFQAEVYLQMTRIQSGAVENTYYHTVNGVEVASNTVVTQTPEEPKTPE
                     EHPQQPERSLPSTGEQASAELLLAGLAMGGAASGLLYSKRKKKEA"
     gene            complement(12072..12578)
                     /locus_tag="VU722_000849"
     CDS             complement(12072..12578)
                     /locus_tag="VU722_000849"
                     /inference="COORDINATES: protein motif:HMM:NF037874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771859.1"
                     /translation="MHKARETKTYGSIRKSKIYGTCGVILGLAALSMISPVIADERTE
                     NKATNAPYAQTSPSSISTENQGKSEEKTGTLEVSISHSSLDETIRKAQEAGLKVEFDS
                     VVDKGTASTASELEKSKRKSRVIIAHKQIVLRKLLKNIVKIKDKIKRTERKSKMKILR
                     RRNNIKRI"
     gene            complement(12724..14658)
                     /locus_tag="VU722_000850"
     CDS             complement(12724..14658)
                     /locus_tag="VU722_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEU1771860.1"
                     /translation="MKLRTTILATTASVTLLGLGNSQPVYANSTTSSQVESLKSEFIK
                     AKREYEQAKSIYDNALSSSPSNTIILSDKYIKALKTAFSDFNISQTERDSAKSILQSE
                     SLRLKNQNSFHKDVADEGERLDVNNLPLAVRQELSFFAQDLINQVRSQVGTPRVSVSI
                     SALDFADKVAKAYVQDNWGWHKMSVSGTLGHDATGINHVAREYGLPTTNSEEEKKGEQ
                     NYENLASRLPGFKTANKAQLKEAIYIGMIEFMFNDTEWMHAQSIAGLNWGNVNSKDYF
                     GLSFSSRSSVSSAHFITVSQEDIKRASKSSFSTAAVSDPTSVNRRQAIKKLEEDYKAK
                     EKIYQDFQKQADSKGSQGQSNQGSATVTEPSKPSAGSAEPTKSIENTSDLRDQWKQEG
                     SYWYYFDRAGKALVNSWKGNYYLKSNGVMARNEWVYDTNYKAWYYFKSDGSYAQNSWQ
                     GSYYLKSDGKMAQSEWLYDSSYKAWYYLKSDGSYAQNSWQGSYYLKSDGKMAQSEWLY
                     DSSYKAWYYLKSDGSYAQNSWQGSYYLKSDGKMAQSEWLYDSSYKAWYYLKSDGSYAQ
                     NSWQGSYYLKSDGKMAQSEWLYDSSYKAWYYLKSDGSYLRDQWFKDGSAWYYLKADGK
                     MAQNETIGAYYLDYSGKWIS"
     gene            complement(14850..15164)
                     /locus_tag="VU722_000851"
     CDS             complement(14850..15164)
                     /locus_tag="VU722_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771861.1"
                     /translation="MNQSKLVTEVTLADLRRLGNQGNATARLDNGDEIKLTSRYGLVP
                     KKGYLAGKLETVWMIVEYSKIYKEIRTIKRGDVLVVRRIKQGNTNRLLLTGKGYHRPT
                     KH"
     gene            complement(15476..16570)
                     /locus_tag="VU722_000852"
     CDS             complement(15476..16570)
                     /locus_tag="VU722_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU1771862.1"
                     /translation="MADITVNQVATQTFYQIPQIFMVNVKKKFSAEGKPTGKIKMTSL
                     YAKKLSNDGKIAYGVLYDRCMLSIYSYRNGELTYVDENGSVFLVYTVEDLMEILDRSK
                     PTVLKIKKELKELGLLREVKQGKNRPNRLYLQNVNAELQEYEHYDAEVVEKGRDKGTV
                     VYHHVKTLDYKGCVLFEIERPGSEEESSILKDENSVLEKPIKSINSGSQKSLPPEVKN
                     FNPIKTEKSHTENNSTRHSSRKPASNSKELDQTAGTCDTPSQKTSGKKFIKPQVYSLL
                     QEIADSYRDHLPWYQHYNMTHRQKMIVGQYIQTGWITSSEVLHCIERIPECDSPFAYL
                     IQSIENLIGERKSEAKMQAHREAEYRYLSN"
     gene            complement(16575..16739)
                     /locus_tag="VU722_000853"
     CDS             complement(16575..16739)
                     /locus_tag="VU722_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771863.1"
                     /translation="MTKEMFVQFSKKAAVNEVMRKTGMSKKRAVKAVEELEREGVLFS
                     MGNGTVMMGV"
     gene            complement(16736..17014)
                     /locus_tag="VU722_000854"
     CDS             complement(16736..17014)
                     /locus_tag="VU722_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771864.1"
                     /translation="MWLETIVCFDCDYEEKWEEDNIFKPIHCPECRDVLDVVERDWLG
                     ETILRSTVQCERCNFLFDHLDFQLGLSECPSCFSKELKLVRQKKEIVE"
     gene            complement(17281..17610)
                     /locus_tag="VU722_000855"
                     /pseudo
     CDS             complement(17281..17610)
                     /locus_tag="VU722_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282476.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17829..19013)
                     /locus_tag="VU722_000856"
     CDS             complement(17829..19013)
                     /locus_tag="VU722_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771865.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLLLFASVLGVTFYLNSQTANSVS
                     LESRLESRIVDNGRAINENEAKLSQMSDTSSEEYQFAKNNLDLQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(19010..19603)
                     /locus_tag="VU722_000857"
     CDS             complement(19010..19603)
                     /locus_tag="VU722_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771866.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFEKGRIYGILAINGSGKTTLFR
                     TISNLIPISSGNIAAPPSLFYYESVEWLDGSLSGIDYLRLIKNIWKSDLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEVPL"
     gene            complement(20003..22243)
                     /locus_tag="VU722_000858"
     CDS             complement(20003..22243)
                     /locus_tag="VU722_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU1771867.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFALSFLYPVIQLNFIFEWLEGMIRLVSQVASRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKRLAVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESEKKIEKWQEKATTSNAQRTLIPYLKSRGVSKIDQLILTNTDKEHIGDL
                     LEVTKAFHVGEILVSKGSLKQKEFVVELQATQNKVRSVSVGENLLIFGSQLEVLSPRK
                     IGDGGHDDTLVLYGKLLDKQFLFTGNLEEKGERDLLRQYPDLEVDVLKASQHGSKTSS
                     SSAFLEKLKPEITLISVGKSNRTKLPHQETLTRLETINSKVYRTDQQGAIRFKGWKSW
                     KIESVR"
     gene            complement(22227..22877)
                     /locus_tag="VU722_000859"
     CDS             complement(22227..22877)
                     /locus_tag="VU722_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU1771868.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(22944..23513)
                     /locus_tag="VU722_000860"
     CDS             complement(22944..23513)
                     /locus_tag="VU722_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771869.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYTSDKGNTRY
                     TFPTNQILEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            23690..24801
                     /gene="ald"
                     /locus_tag="VU722_000861"
                     /pseudo
     CDS             23690..24801
                     /gene="ald"
                     /locus_tag="VU722_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(25168..25428)
                     /locus_tag="VU722_000862"
                     /pseudo
     CDS             complement(25168..25428)
                     /locus_tag="VU722_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(25431..25931)
                     /locus_tag="VU722_000863"
     CDS             complement(25431..25931)
                     /locus_tag="VU722_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1771870.1"
                     /translation="MIDQLSKYYSCRILTEKNIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFIGFWNGSDLVAVMDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKACLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            25967..26146
                     /locus_tag="VU722_000864"
     CDS             25967..26146
                     /locus_tag="VU722_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771871.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQQYI
                     LLQANFLKISRVQLQ"
     gene            complement(26124..27092)
                     /locus_tag="VU722_000865"
     CDS             complement(26124..27092)
                     /locus_tag="VU722_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU1771872.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVILAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(27178..27393)
                     /locus_tag="VU722_000866"
     CDS             complement(27178..27393)
                     /locus_tag="VU722_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU1771873.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(27402..28256)
                     /gene="cvfB"
                     /locus_tag="VU722_000867"
     CDS             complement(27402..28256)
                     /gene="cvfB"
                     /locus_tag="VU722_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU1771874.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(28316..28873)
                     /gene="frr"
                     /locus_tag="VU722_000868"
     CDS             complement(28316..28873)
                     /gene="frr"
                     /locus_tag="VU722_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU1771875.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLII
                     PVLTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(28894..29619)
                     /locus_tag="VU722_000869"
     CDS             complement(28894..29619)
                     /locus_tag="VU722_000869"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU1771876.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRSAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNI"
     gene            complement(29703..31037)
                     /gene="trmFO"
                     /locus_tag="VU722_000870"
     CDS             complement(29703..31037)
                     /gene="trmFO"
                     /locus_tag="VU722_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU1771877.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESATSGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(31381..32703)
                     /locus_tag="VU722_000871"
     CDS             complement(31381..32703)
                     /locus_tag="VU722_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU1771878.1"
                     /translation="MSLSNDFKEFCEDELPMTDEEWEKWENRLKEITKRLNRKFYSLD
                     ELDDQETDNGLIVGSVGRTTAVRNVSDFDYIFSLPSEVYRRFDSYEGNGQSALLQEIK
                     NELLKRYPNTKIKGDGQVVVIDFSDGGKIELVPAFEKSDGNFKYPDSRNGGSWKTTKP
                     KFEIEKCKSLNSNFNSHFSNLTRLIRQWKNHMGFSFKGLLIDTLISDLIDDKGISEIY
                     YSDYNILLKDIFEYFSNQDKNREYWYALGSNQKIYNNDGAKFVNKAKQALKKIEDASE
                     EKLTEVYRQLFGRKFAQSTSTTNRASNEEFIDELFNVNIEYNIVLECEITQDGFRKAL
                     LSDFLKSRFKIKNRKSLDFEIIKSDIPDNLLSDVKYYWKVRNIGAEAIRRNCERGAIF
                     SGKIKHHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            complement(32703..33266)
                     /locus_tag="VU722_000872"
     CDS             complement(32703..33266)
                     /locus_tag="VU722_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HEU1771879.1"
                     /translation="MSKNQEKLHFQLKKFIVNVGWTHKIHAVRIDELESYIRWFRIAT
                     IIISGVVSSGLVGILWFDEYWIKLVTAFLSLVTTIIFSITKEFNFEERLALERKSVDE
                     LWNLRVLAEILLSEVVYNGKPSSEIQEFFEELKFRRDATYSQLSNASPKNVSKASKLI
                     KSRKDNDYEEDYRYFIPKELMEIKEEE"
     gene            complement(33284..34078)
                     /locus_tag="VU722_000873"
     CDS             complement(33284..34078)
                     /locus_tag="VU722_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEU1771880.1"
                     /translation="MELNFQDKSFIKVFFNSDGYVLNFSNSTFANFTFNSVGVNIQEK
                     YGGSKGKALQAFVDNEPDELVLKLALDLLRYYEDLPDSYYEKTEERNSQALKLKERLS
                     KYEVSQIAYLNNAAKSLSDYFDSDYIDKQMGIMNEMISRSPADAIGKAKELLESCFKH
                     ILDHEKIEYSNSNDIATLQKKVFKFLNLDSNENISAKNNQDVKVVLSGLNQIIKGINN
                     LRNDKGDGHGKGANFIELPPRYASVVVGSALTVVSFVWETYQDKQK"
     gene            complement(34103..35143)
                     /gene="dcm"
                     /locus_tag="VU722_000874"
     CDS             complement(34103..35143)
                     /gene="dcm"
                     /locus_tag="VU722_000874"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU1771881.1"
                     /translation="MKKLKIASLFSGGGGTDIGFAGGFDFLGKHYADNQIEIVYANDI
                     EDSANKMFEKNFGVTPDNRNIREIKSDEIPSFDILTGGFPCQSFSVSAQNPKRLGIKD
                     EKGTLFFEMVRVLKAHQPKAFFAENVKGILSANNKEAFPLIIEEFEKAGYNVSYKLCV
                     ATKYGVPQKRERVFIVGIRKDLNFTFEFPEEPIQNVEDYTPLKVILQQDIDEKYYFSE
                     RAVQGMLNSKSGKKMNKGRAQDIEQPSNTVSSHLAKVSLNSTDPVLLENGRYRRYTPR
                     EVARIQSFPENYELLGSEGAQYRMLGNAIPPVMMWYIAEKLVSDLRNSDVIAKQQKLE
                     ESFGQLDLFEAS"
     gene            complement(35140..36540)
                     /locus_tag="VU722_000875"
     CDS             complement(35140..36540)
                     /locus_tag="VU722_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU1771882.1"
                     /translation="MYQVPEKYYFRLHHPRPRFKNDVENVLVYMATNISYLGILPKKE
                     FSQQLNDIIKQYAGNADKTEKTINNWRTEISSLFGMMIEKEGFVYSGNRAKELTEDQD
                     LIRFFKTFLYNFEYTGGHLKDNEIVKLCQIGVQFKPAQYLLELFTEASQAEEKTIYLT
                     DEEVAHCIFNDLRCTRDREPVLEIWNRIKENRASKVAYDTKGDVIRYAKDVLDYMVIA
                     SLLTVQGGRYKINSMEEQATNDFLQSDATFDGYAQFIGNASTTIEDVRNFRSAWFEYV
                     NRDLGDIDFRTNFNLYLPSDIDFTEEKTDIIGHLTEHIEYSEKISTAVVGSSGEAIVI
                     NHEKQKLREHGQEQLLHLVNFIPTQFGVGYDVQSFECDDSELRKYIEVKTTVSNASIT
                     FNSFHITPNEWRTAKSVRDRYYIYRLQISKHSKKLFIIKNLYELVKNEKMLLIERKDG
                     YDARFSSSVGFEENLI"
     gene            complement(36543..37598)
                     /locus_tag="VU722_000876"
     CDS             complement(36543..37598)
                     /locus_tag="VU722_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU1771883.1"
                     /translation="MKKYNIVDLFSGAGGLSYGFEMAGFNVLLGIDNDEKALETFQKN
                     HQNSEILCGDIANISYEEDIKPIIGEQKIDIIVGGPPCQGMSLSGPRRFDDPRNKLYL
                     SYIRLVREIQPTAFVIENVIGIVSLFKGQIKDTIIEEFSKMGYKVQFKVLLASDYGVP
                     QNRKRVIFVGTRNDGFEYPEALGTIITTEMAISDLPTLENELGEIEMSYVSEPQNDYQ
                     KLMRKRSNVVLNHVAAKHSEKVISTIALVPDGGNYKNLPKELRETRKFNVAWTRFASW
                     KPAPTIDTGHRHHFHYKYNRVPTVRESARLQSFPDDFIFYGSKTQQFRQVGNAVPPLM
                     AQQIANNLLKYLKNNEE"
     gene            complement(37816..38685)
                     /gene="rsmI"
                     /locus_tag="VU722_000877"
     CDS             complement(37816..38685)
                     /gene="rsmI"
                     /locus_tag="VU722_000877"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU1771884.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKVGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(38688..39005)
                     /gene="yabA"
                     /locus_tag="VU722_000878"
     CDS             complement(38688..39005)
                     /gene="yabA"
                     /locus_tag="VU722_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU1771885.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(39045..39935)
                     /locus_tag="VU722_000879"
     CDS             complement(39045..39935)
                     /locus_tag="VU722_000879"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU1771886.1"
                     /translation="MKQEQLKAWQPAQFDRFVRILEQDQLNHAYFFSGFFGSLEMAQF
                     LAKSLFCTDKVDVLPCENCRNCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEQLILLLEQMGLVKKKATLLAQFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRVLEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(39932..40570)
                     /locus_tag="VU722_000880"
     CDS             complement(39932..40570)
                     /locus_tag="VU722_000880"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU1771887.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLLILEEKGVEVLTSREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(40790..41587)
                     /gene="proC"
                     /locus_tag="VU722_000881"
     CDS             complement(40790..41587)
                     /gene="proC"
                     /locus_tag="VU722_000881"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU1771888.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDELLLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVGLGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEVHAFRGTVMDAVHQAYKRTQELGQ"
     gene            complement(41591..42853)
                     /locus_tag="VU722_000882"
     CDS             complement(41591..42853)
                     /locus_tag="VU722_000882"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU1771889.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTVL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLDQ
                     MLVAERKEVGLEPIQFRLDSKASQFVSGQVAEAQDFDTEFLDYVLAVKVVSSLEEAVT
                     HIETHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(42863..43993)
                     /locus_tag="VU722_000883"
     CDS             complement(42863..43993)
                     /locus_tag="VU722_000883"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU1771890.1"
                     /translation="MKKRSETIKYRRIVFKVGTSSLTNEDGSLSRSKVKAITQQLAML
                     HESGHELILVSSGAIAAGFGVLGFKKRPTKITDKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLSRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
BASE COUNT        12709 a         9925 c         7390 g        14082 t
ORIGIN      
        1 cagaaagcaa cgtgaccata gattggcgat gccccagcta caccattcat gaatacagct
       61 gcagaacctg gtttaggagt cgttgaaatg tcatatcctt gcgcttggcc actatcaacc
      121 cactgattgg catttcctag atagggatga ataccaactc caatttgagc aaagcgatta
      181 tagacatacc aagtacaatt ccctagttca taagcgttac ctgaatagcc ttgtccttct
      241 aaaagtgctt gatcggtagg tagtccataa ggtagcttat ctttatattc tgctggaact
      301 tgcttgctag aaacacctgt cgaacctcct cctttatttt ttaagaaatt caaccattga
      361 cgagctgcat tttgtcgttc taagagctta ttacctggta ctcccaacca agcgttcaag
      421 aagtcctctg caagagcttc tacggaaccc gtcgatgtca caattcttct gaatgctgca
      481 cgtctagttg gatcatcttc ctccagaaga aattttgttt ggacttctgc agaccaaata
      541 tctccattca ctgattttgc aaaattccac aatgcaagag cacgagggcc agtaaattga
      601 ccaatcccaa tcccgatata gtgcaaacca ttgactagat accctctttc atttagaggc
      661 aaagtagggt acatagcttg aaaggctccc cagttgccaa ctaaattttc tgcagttggt
      721 tctttagcaa ctttatcaaa ctgattatta gttagatagt ctgtttcata gcgtttaaaa
      781 gtgatggaac tctcaatatc aaatcctccc aaaacggctg caatcccttc atcagttgcc
      841 tccggtatat tctttttaat cgcatccgca aaagctcttg cacgtcttcc tttctctcca
      901 gatgtttcaa tattactgac aacagacgtt gcttgagtgt actctacacg ctggaagtaa
      961 aaaccgacat tgacataagt ccaactcttt tcaacattac catctttgtc tttcttattt
     1021 aatcgatcag gttctagctt ttgataataa acggtttgat ttccttcagg tgctaccttt
     1081 ccaataatat ctccagcttt gacgtgatca cctgttttat agcgaatcgt atctacgttc
     1141 ttatacagaa acttggaatc ctgatcacta atttctatgt cactcccctt aacttcaact
     1201 ttcccatcta aaacagctaa cagagactga cctcctgaaa cctgcaaaac agatccatta
     1261 aaaacttccg tcttcgattt atatccaaaa cgctcaataa tctgaagagg tgcctgcgat
     1321 tcaggttgtt cttctgtata aaatggatta tctagttctt gaagcaacat atattttcca
     1381 ctatctctag caatttctaa gagctcttta tactcctcta actcgtcctt atcaagctta
     1441 tagagattat ttttggtata aagctcttcc atcgttttaa gattgtcttt atccccattc
     1501 aaattcttcc ataaggtatc taagtaaagt tttccacgat tctgttgtga aaaatagtta
     1561 ttcccgtcta tacgaagctt atctgaaata tcatcatact tataattcaa gtataaaagc
     1621 ggatcgtcaa tttttgtcca ataatctacc ttgtcattcg atttttcacg atccaatttt
     1681 gaaagataca accaggtatc attcatatca aattcatctt gacgggtaat tcctgaacta
     1741 ccgataccaa gtatagccag aaacaaaagc agaccaaatg caatcagata agcctttaag
     1801 ctaaatggat ttttgataat aactttaagc ggtttagaac ctacacggta aaacttccta
     1861 gccttcttag ccactttccc tgttttagaa gtagccaagc gtttcttata atcctgaata
     1921 cgacgagaga gttttccttc ccaagaaaat tctcttggag tttgagtgaa gcccctaccc
     1981 ttagccttat tgtagactct atttccaagg ctatagctcg atttaaccat tccttggcca
     2041 agtttaccgc tatacttccc aatcgttttg attcgtttcc cttgaatctg aatatcctga
     2101 taccgatatt tagttcgtgc tatatctgat agtgtatcat cctgatgcgc aacagagcta
     2161 gcctgttgat tagcaactcg ttctacagat tgttttgccg cacgaagaaa cttcttcttg
     2221 cgtgaaccac cattagcctc ttgagcgact ttaaaagttc ttttagaagt ttttttctcc
     2281 agtttcgcct tatctaattc ctgcttaagg aagacccgct ttttattgtt cctatctaat
     2341 tcctgcttaa ggaagacctg ctttttaatt tcctctggac gaagtgactt tccttctttt
     2401 ccaagatttc ttccttgttt ctggatattc ttgtactctt tttggattct cttatactct
     2461 ttttgtattt tcttgacctt gttcttagaa gctcgaaatt ggcttcgact cttctttacc
     2521 aactgacgtt tagagtgagt ctgagattgt aacttcgtaa gttgttttgc gctatcttgt
     2581 tgaaccgttc ggtaattctt acgaactttt tctagctttc gatctaacct atgaccgatt
     2641 gtttttggtc tgcctttctc ctgatccata gtgagacccc taagcgtctg ttgcgactaa
     2701 gttatacaac ttagtattct ttggtattgg attttcaaat ggcactacaa ctggcccagc
     2761 tacgattaag ccagtacctt tagcttttgg ccgtgctaag tagcgaatct gtttatcagt
     2821 cagattgaca atctctttta ggatagccaa atcttggggc ttttgtttga gcaaaatcat
     2881 aaactcacta tttgagagca atttccgacc ttcttcaaca gcagccagcg tttctacgtt
     2941 ctgggtaatt cctgttggaa tcgcaccata tttccgaatc cgtgaatata acgtagtaaa
     3001 gaagtctgct tgagccttat ttttaaatag aatctgcatc tcatcaaagt aaacccaagt
     3061 agtacatttt ccttgatttt ctacaatttg attccagata taatcctgaa tcaccatcaa
     3121 agcgaacggc ttcaatttgt gcgacaactt cttcaggtta aagataacaa agcgatgatt
     3181 aagatccacg ttggtattgt gagcaaaaat atcctgagaa ccagttgtat aggtctctac
     3241 tgctaaagct aagtcttgtg cttcaggttc gggttgttct tttaagacct ggtgccactc
     3301 ttttaatgtt ggggtaaaat tctccgtcaa atagcgttca taagtcaccc ctgttacccg
     3361 gtcaataatc ccaatctggg catctgtcac ctctgacaga atcgattcaa acaatcccat
     3421 taataagttt gccttatctc caatcggatc gtcatcctca tcgtccaaac gatctagatc
     3481 tggtagatct aagagattga tatgtgtttt agatccaatc gaaatatcca ccatctgagc
     3541 accgaaagca cggccaatat cagaatattc atcttcggga tccacgatga tcactcggtc
     3601 ttctggatat ttcagtaaag ttggaataac ttctccaccc tttattgttg tagatttacc
     3661 agatcctgaa gaacctaaca caactcctga acccgtgttc aaatcacgct ttctatctag
     3721 tgtaatgata ttgtttgata actgattttg accatagtag cgagcgagtg agctttcaga
     3781 cttcaagtcc acgttggtaa aaggaacttg cgtagcaata ttagctgtcg tcatctttct
     3841 cataaaattc ttcttcacat tcaagaagca ctctccaata ggtaaaaccg tatttagagc
     3901 ctcttcttgg taataataga gatcttcaaa ctctacccct agcttccgtc cagcacgctt
     3961 aatcttctgc tcattccgtt gtagttcctc ctggttatcc gccttaaaat acactgcaat
     4021 caaaccagaa aagattttct ggtcatactc agtaatctcg tctcgccact tcttggtagc
     4081 ttctgagatt tcttggtcac gaccagcaac gaccgcatca tcaaagatac cagattgagc
     4141 cgccttacgt ttcgaacgta acttcccaat ttcagcatct gtctctgcat cgtcaatctt
     4201 ctctaagatt tcaacgttct catagggttc tgcatggata gtaatagcca gttccagccc
     4261 cagtgtcgtc aaatctcgaa taagccgatc agacatccag ttaggatagc gacgtgcata
     4321 gagcaccttg caccaacgat catctataat catgcgtttt tcttgaaatt caatcctgtt
     4381 tggcgcaata aatgatttag tgaataaacc tgtcaaagca atttctttgt aatcaaaatt
     4441 gacatacggg ttatctcgta acagttcaga aaagaccttt aggcgatcca aaccattcat
     4501 atccctgaaa gtaatatcag attcctgaaa ttgagttcct aaggaaactc caatatcttg
     4561 taggatcaac tgcgcctgct ttcggtcatc cgcattcgtt gaaatggtca catacttatg
     4621 tacctcgaag ttgttagcat gtgtcgtaaa tcgctccttg atcatctcat ttagctcctc
     4681 acgatagtcg tcaaaaccat catttgtttc ttcatacaag atattctgca aggagttatc
     4741 cgatactcga cggttaatga ctaagagctg gtagttacta ccctcatcca gtgaattaag
     4801 agcatccatc gttgtatcaa tgatactctc tttttcatct tgttgagcag ttgagtacga
     4861 agcatccccc aacataaagc tccgagaata cttctcacgt gcaatgtgca tcaatccgtc
     4921 ttcatggagc agtgtataat tgatggtgtt ttgtgtcgta ggtttcatct ggcgacgcaa
     4981 gcgatcaatt tttttctttt ctgctttttc tagtttttct cttttgcttt tgaataaact
     5041 catctttcgt atacattcct acctttccaa attctatctc ataggttcgt tgttggattc
     5101 ggaaaaagaa attgattttt tctttaatcc gcattcgctt agtcattccc gtaccgtaca
     5161 tccctccagg aacgacaaat agagcatccc aaagatagat gtaccaatca ggtagaccaa
     5221 agaagtaact agcagttgtc cctgagacag ctattatcaa acacaggtat agaacaagca
     5281 ttctactagt taagccaaat agaataggct tgtcctcagt ttcaaattct cttaaaaatt
     5341 ctgatccaat ttttttcaat tagtttcctt cccatcaaaa aaaaacagtc cgtttagaac
     5401 tgttagtctt atgtcattta tttatcacgt tcctttacaa gcatagctac agcaatctca
     5461 gattcctacc ccttcagtat cgaataggct tctgttagcc gttttttgtt cctgaaaata
     5521 gcgttcaaag ttttcatctc ctttgaagac cattttacca cgatccatat atttaatcca
     5581 ctgttccaaa cggtaaacat actctgtttg actgatacta tcagctatag cacagtacgt
     5641 tatatcttcc tgaagaaggg taagaattct catgccataa aaagcatctt gcttagcttc
     5701 tgcatagcgc caagcataaa tatatagttc gtcaccataa ctactcatcc gaacggcacg
     5761 aggaatctca gatatcttaa ctttaccatc caatatccac tccaataaag gctccgataa
     5821 taattcatgt tcataggcaa accaagaaag acgtgttatt tcttgttcaa gagaagttat
     5881 tttatccttc aactctcttg tcccatgttt cttttgtaaa tcattaaatt gtttatttcc
     5941 tatctccttt aacgtttcca ttgatagtca cctctttcta tagaaaacat ccacacgatt
     6001 ctctaaacat aggtaacatc gattaattct aatttttcta cacatagatt acactcctaa
     6061 aagctgcttg gcttttcgac tagatccaac cattacaaag atatagataa cccccttggc
     6121 aattgaagca aaggctgttc cccaggaatc actggaacca gtcgtaacct ttaggatatc
     6181 tgctgcaaca atcgaatcat aaacaacaga aacaataatt aggatgacac caataagggc
     6241 agaggctgca aagtatttca ggaagttaat cgtaacagat cgcaacgaat ccatcataaa
     6301 gaaggctact aacaatggag ctaaagcctt aagcatatat aaatccaagt aacgtaagaa
     6361 aacaataatc cctaaaataa cgttagctac tccacttaca gctttcccta cgaaagtaat
     6421 gatagttttt tcaactattc ctttcccacc agaaatatta gaatcaatgg ttgctttaac
     6481 agtaggtgtt acatgagcaa ttacctttac aataatatta agtaattcca gaatggcatc
     6541 gcaaatttga gatgaggcag aaatcatgat gaaggcaaat aaatacttca tcaaggcctc
     6601 tagccaaatc ttttgggtta gcgaacctcc tctggactta accatttgtg accacgatgc
     6661 catttcaaac cagaaaaaaa gacctaaaag gatataccca ataggtctga ctgcatcagc
     6721 catcatattt acagcttgat ttgtagcaga gccataacta gaaagagagc ttgttagctc
     6781 tctaatatct aaattcatag gctactccta aaattttagc tgtgataatg ctgcaacgac
     6841 tgcggccgca atccctgcag aagcaacagc caagaacgca ccattaatca tagaatcaga
     6901 cccatcatct tgtctttgct tatctttatt ctttcttcct tgaatataat caaccgcacc
     6961 attccagatc cagataagac ctgtgattgt tccaactaca cctagaccag taataatttt
     7021 tgtaatgatt tccattttgt tttacctctt ttaatttcat ttttttataa caaaaggcac
     7081 tgcagagatt tctacagtgc caaacacaat actattttta taattcttca aattcttcac
     7141 gataaatcgt ccgaacagta gctactagaa tactgaggcc aataataatt ggaacttcaa
     7201 aattcggata tgggaaaaat aaccctcctc cttttggtgc atcaaccact tgaccagcag
     7261 taataagtga atcatgggac attcctaaaa tatgcggtgt ataccatcca aaaatattat
     7321 caattatgtt ttcgcttggg aaattgaata gatgatgaat gattgccatt cccccaatca
     7381 atacgattgt tatacatatt ttagctataa cccacagaat aaacatacca atagtggatt
     7441 ttacaacatt aatacaccaa agaacgatat aaaagggagc tgtaaaaatt ctaatgatag
     7501 ctacccataa ccaggaaaaa tcacttccaa atttcataat cctactcctc cacgatttac
     7561 cgttattata ccataaaaat agcttatttt aaagattcct agagtattct aagcctcttt
     7621 tttcttgcgc ttgctgtaga gcaatcctga agcagcaccc cccattgcca gaccagctaa
     7681 cagcaattct gcagaagcct gctcacctgt agatggcagg cttcgttctg gttgttgcgg
     7741 atgttcttca ggagttttgg gctcttctgg agtctgagtc acaaccgtat tggaagcaac
     7801 ttccacaccg ttaactgtat gatagtaagt attttctact gctcctgact gaatgcgtgt
     7861 catttgtaga tatacttctg cttgaaactc tgatgtttct aaaatcgact ttaagagagc
     7921 atcatcaaag ctaatatcta ctttaccttt agccttgtct accacttgac ttgtgaactt
     7981 agttaattca tcaccagctt tgaatttttg gccatcactt gtttcaaaat ctacagcagc
     8041 aaataccttg taaacactct gataatcatc atgtgtttca tcgtagtcat cgctaaattt
     8101 atactcaaat aactgttctg agcgatcttt tggcactagg gaaccaacta atttgtaatt
     8161 aaatgtttga ttcagtttga cctcttttcc atccaagctt tctttgctta gatggtcgat
     8221 cacaacatct ttcttcggtt cgatctttgg tacattattg actactgttt cagttacata
     8281 atccatccca aaatcaattt gataggctgt attttcatac ttaccacctg tttgacccaa
     8341 ttccttctta acagtcattg gattggtaat ggtcagaact tctccagctt gcacgtaggt
     8401 cttgtagaat tcctctggat tctctgcctc gaatacttga atcgctcctt tcggagtgaa
     8461 atggctagac ttcagggctt cttggacacc tgatggtgcc ttagctagac tctcataaag
     8521 agacattttc aaatctttga ctacttgacc tttagaatcc gttacttgaa caccgtcttg
     8581 attgatggta acagcttctt ctggataatc atcaacgata tagaaccctt taccaatacg
     8641 gtctttatct gcttcaatgc ccttgtattg gctataatct gccgttacct tgtagtagtt
     8701 gacagagtct gccaatacct gtttcccatc gatgttcacg cctgctttat tcaaattctt
     8761 cttggtaggt ttaacagtag gaacattatt gacaactgta tctgtaatat aagctgaacc
     8821 aaaatcaagc tgataagctg tattctcata cttaccacct gtttgaccca attccttctt
     8881 gacagtcatt ggattggtaa tggtcagaac ttctccagct tgcacgtagg tcttgtagaa
     8941 ctcctctgga ttctctgcct cgaatacttg aatcgctcct ttcggagtga aatggctaga
     9001 cttcagggct tcttggacac ctgatggtgc cttatccaga ctatcataaa gagccatttt
     9061 caaaccttta actacttgac ctttagaatc cgttacttga acaccatctt gattgatggt
     9121 aacagcttct tctggataat catcaacgat atagaaccct ttgccaatac ggtctttatc
     9181 tgcttcaatg cccttgtatt ggctataatc tgccgttacc ttgtagtagt tgacagagcc
     9241 tgctaagacc tgtttcccat cgatgttcac acctgcttta ttcagatttt tcttggtagg
     9301 tttcgcagta ggaacattgt tctctacctt atccgtctgg tagccactac caaagtctaa
     9361 ttgataagct gtattctcat acttaccacc tgtttgaccc aattccttct taacagtcat
     9421 tgggttggta atggtcagaa cttctccagc ttgcacataa gtcttgtaga actcctctgg
     9481 attctctgcc tcgaatactt gaatcgctcc tttcggagtg aaatggctag actccaagga
     9541 ttcttgtaca cctgatggtg ccttatccag actatcataa agagccattt tcaaaccttt
     9601 gaccacttgc cctttagaat ccgtcacttg aacaccgtct tgattgatgg taacagcttc
     9661 ttctggataa tcatcaacga tatagaaccc tttgccaata cggtctttat ccgcttcaat
     9721 gcccttgtat tgactataat ctgccgttac cttgtagtag ttgacagagc ctgccaagac
     9781 ctgtttccca tcgatgttca cacctgcttt gttcaaattc tttttggttg gtttaacagt
     9841 aggaacatta ttgacaactg tatcagtttg atatccgtta ccaaaatcaa cttggtaagc
     9901 cgtattctca aatgattttc ctgtatttcg cagttcttcc ttagttacca ttggatcaat
     9961 aattgtaacc gattttcctg atttaatata ctggttaaaa taagcttctg gatcatccac
    10021 taaaaatact tggaaagcac ccttgggctt aatttcagaa ctagcaagaa aagctttaac
    10081 cttatcatta tcaacggcat ctatagaatc atactgatac accgagatac cagcaacttc
    10141 ttttccttcg ctgtcaatat aacgaatgtc cgattgatta atcgtaacag cctcttctgg
    10201 gtaatcatca attgctccga atccttttaa aatagtagat gaatctgcct tcatcccctt
    10261 atattgatca taatccaagg taatatggta gtaatttgtc gaaccaacta gaactggttt
    10321 accatcaatg ataactttat ccttattgta attatgttta agaggttgaa tgaaattatt
    10381 attcggattg tccggatcat tcggtttacc aggtgttgaa atctgaacaa tgtttgaata
    10441 acttgcgtac ttattgttaa tctttaattg gaagttattc ttgtaggtcg ctccatcatt
    10501 cgttacttta ccaactaaaa ttggagctgg tacttgtact tccttactta aatcttgatt
    10561 aagcttagat tttaaacttt ctaagccttt catccgaaca acatggctcg actcgtcata
    10621 agttaattca aaatctgagc taattttttt ggaagcttca acatctaaca caaaacctga
    10681 aggcaaggca tccacaattt caaagtctgt aatagcttca cgattagctg gaagaggctt
    10741 agttgttagt tcccactgta ctgttgaaag tttaggtaca tagcttttat caatagattc
    10801 accagaagaa ttttttacaa acttttctag gtcaggcatt gcctgtaagc gtgcatatct
    10861 aacccttact gttggagggg atactaaaga ggggatctct ttttccttta tctcctcagg
    10921 tttgggtggg agtacctctt caggttttcc agttggagaa ttgggtggag tagtttcaac
    10981 ttcataagtt ggtttgcgag gtggatttac tggtggaatg cttttcaact ccgccccctc
    11041 cccaagaatt gtgaagacaa cgttttgaac atttccactc aaattctctg catcccattc
    11101 agcgggagtt cttccctctg tcgaaccagg agatgatgtg tgaaggtacg ttaaactaga
    11161 accataccct actgaagcaa aggaagcctt aggaatatct gaggtatcat taactccatt
    11221 ttctactccc ttcataacgc gaccatcaaa atccaaacct gaaccacttg gattaagaac
    11281 cattccacga ccagatgagc cataactcaa atttgaacct tgaccccaat ctacatcggt
    11341 aataactgtt ccaattaaga gggaaacagg agttgtcgta ccttcaatat aaaaatcaaa
    11401 aaccatttcc aaacgggtat gattattata gacaaagtag aaacttccac catctccacc
    11461 cttgaggtag atatctgaat ctgtcacagg aacaccattt cgaacttctc cctgatagtc
    11521 tcctaaatcc gaaaccatga cttttgccat gatctttcta ccatctgtca acgttccaat
    11581 attatgaata taaaatgtat ctccaaatgt tggagattta atgatatcat aagtttccgt
    11641 actatcctta ctaactcgag ttcctgcgcc tcctgttaca taagtatctg catgataacc
    11701 taaaaaacca cgcatactct ctactggtag attatcatct ggtactactg taaaatcatt
    11761 ataatagtct aagcttcccc gaccagctga attatatcct ccataaactt tgaaacctgt
    11821 ttcagatcca aataaaggct tacttgtttg aattgcatct cgctcagctt taatagttgc
    11881 tagcttcttt gtatagtctg tcaaagagct ttcataagct cctctcttag cttcatttcg
    11941 ttttcggatt tctgcattct cttgattgat acgatctatt tctgcctgat tctctcgttg
    12001 atttttttca ttctctgcac gaatactagc attcttctga ttaattcgat tcacttcagc
    12061 ttgataagaa gttaaatcct tttgatattg ttccttcttc gcagtatttt catcttggat
    12121 tttctttcgg ttcgtttgat tttgtctttg atcttcacga tatttttcag tagctttctc
    12181 aatactatct gcttgtgtgc aataatcact ctcgacttcc ttttgctttt ttccaactca
    12241 gaggctgtac ttgcagttcc tttatctact acagaatcaa attccacctt caatccagct
    12301 tcttgtgcct ttcgaatagt ttcatctaaa ctggaatgag aaatagaaac ttctaacgtt
    12361 cctgtttttt cttcactctt tccttgattt tcagtagaaa tactgcttgg actcgtctgg
    12421 gcataaggcg catttgtagc cttattttca gttcgttcat ctgctataac tgggcttatc
    12481 atgcttaaag ctgctaaacc tagtatcact ccacaagttc cataaatttt tgatttccga
    12541 atagatccat atgtttttgt ttctcttgct ttgtgcattc tatctcctta tctaaaatat
    12601 caatcaatat aaaacctcaa atgttggctc tcgaggtctc ttataatata aaatcatctc
    12661 tttcctttcc aatagaaaaa agccagcttt cactgacttt tctatacaat attgtaatga
    12721 attttaagaa atccacttac cagaataatc taaataataa gcaccaatcg tctcattttg
    12781 tgccatctta ccatctgctt tcaaataata ccaagcactt ccgtccttga accattgatc
    12841 tctcagataa cttccatctg atttgagata gtaccaagct ttataactgg aatcatatag
    12901 ccactcactt tgtgccattt ttccatctga cttaaggtag taacttcctt gccaactatt
    12961 ttgtgcatag cttccatctg atttgagata gtaccaagct ttatagctgg aatcgtatag
    13021 ccactcactt tgtgccattt ttccatctga cttaaggtag taacttcctt gccagctatt
    13081 ttgtgcatag cttccatctg acttgagata ataccaagct ttatagctgg aatcgtatag
    13141 ccactcactt tgtgccattt tcccatctga cttaaggtag tagcttcctt gccagctatt
    13201 ttgtgcatag cttccatctg acttgagata ataccaagct ttatagctgg aatcgtatag
    13261 ccactcactt tgtgccattt ttccatctga cttaaggtag taacttcctt gccaactatt
    13321 ttgtgcatag cttccatctg atttgaaata ataccaagct ttatagtttg tatcataaac
    13381 ccattcatta cgtgccatca caccatttga tttgagataa tagtttccct tccaactatt
    13441 aacaagagct ttccctgcac gatcaaaata ataccaataa cttccctctt gtttccattg
    13501 gtcacgcaaa tcagatgtgt tttcaatcga tttagtaggc tcagctgagc cagcgcttgg
    13561 tttacttggt tctgtcacag tagctgaacc ttggttagac tgcccttgag atcctttact
    13621 atctgcttgt ttttgaaaat cttgataaat tttttccttg gctttgtagt cttcctctag
    13681 ctttttgatt gcttgacggc gattgacact agttggatca ctcacagcag ccgtgctaaa
    13741 gcttgatttg cttgcacgct tgatatcttc ttgggaaacc gtgataaaat gggctgaact
    13801 aacagaagaa cgactagaga atgaaagccc aaaataatct tttgagttca catttcccca
    13861 gttcaagcca gcaatactct gagcatgcat ccactcagta tcattgaaca taaactctat
    13921 catcccaata tagatagcct cttttaactg agccttgtta gctgttttga aaccaggtag
    13981 acgagaagct agattttcat agttttgctc cccttttttc tcttcttcag aattggttgt
    14041 aggcagtcca tattctctcg ccacatgatt gattccagtc gcatcatgac caagtgtacc
    14101 agatacgctc attttatgcc aaccccagtt atcttgaaca tatgctttcg ccaccttatc
    14161 tgcaaagtca agtgccgaaa ttgaaacact gactctaggt gtcccaacct gagaacgaac
    14221 ttggttaatt aaatcttggg caaaaaatga caactcctga cgaacagcta gcggtagatt
    14281 gttgacatcc agacgttctc cctcatcagc aacatctttg tggaaactat tttgattctt
    14341 taatctcaaa ctttctgact gcaaaataga tttcgcactg tcacgttcag tctggctaat
    14401 attaaaatca gaaaaagccg tcttcaaagc ctttatatac ttatcactca gtataatcgt
    14461 attgctaggt gaagatgata aagcattgtc atagatactt ttagcttgtt catattctct
    14521 ctttgcttta ataaattcac tttttaagct ctctacttga ctactcgttg tactatttgc
    14581 atacacaggt tgactatttc ctaacccaag caacgttacg ctagcagttg ttgccaagat
    14641 ggttgttctc aatttcataa tcttatctcc tttttgttta aaaacgttct taaaatattt
    14701 attttatact tttattttac catttttaga ggttgttctc aatttttttc ttaattttca
    14761 ttcatctatc cgcttaatca aagataggac gtttaaaaca gttcaaatct cctctccttg
    14821 atgaaacaga tagatgaggc tctatctgtt taatgcttcg ttggacgatg atatccttta
    14881 ccagtcagca gtaaacgatt ggtatttcct tgcttaatgc gtctaaccac taaaacatca
    14941 cctcgtttga tggtgcgaat ttctttataa atttttgaat attctacaat catccaaact
    15001 gtttctagtt tacctgctaa atatcctttt ttaggtacca aaccatatct gctggttaat
    15061 ttgatttcat cgccattatc aagtcttgcg gttgcatttc cttgatttcc taagcgtcta
    15121 aggtcagcta aagtgacctc tgtaactaat tttgattgat tcatcttatc tcctccttac
    15181 tgaatcaagg ctgatttaca gccatgccga ggtatgacgt acatacctgc tgtatttttt
    15241 acacacggtt ttaagtctag aaaccgcaaa ctccttcagc ttaggctttg cctgctttta
    15301 cgtggtggaa cagcactaga tatccttttc tagcctacac accgcccttg ttcttctttt
    15361 tatgcttagt tccgctaatc aggacagtgg ggatattcaa ttttcaaagg tcaaaagtag
    15421 ttttatgact tgctcaggtc aaaaaagcta gatttagtct catgtcatct atagcttagt
    15481 tactcagata cctatactct gcttctctat gagcttgcat cttggcctcg ctcttacgtt
    15541 cgccaatcaa attttcaata gattgaatca agtaagcaaa aggactatca cattcaggaa
    15601 tccgttcgat acagtgaaga acctcactac ttgttatcca tcctgtctga atgtattggc
    15661 caacaatcat cttttggcgg tgagtcatat tataatgctg gtaccacggt aaatgatctc
    15721 ggtagctatc tgcaatttcc tgcaagagag aatagacttg aggtttgata aatttcttcc
    15781 cacttgtttt ttgagaagga gtgtcacaag ttccagcagt ctgatccaat tccttagaat
    15841 tggaagcagg ctttctagaa ctatgtctag tactattatt ctcagtatga ctcttctcag
    15901 tcttaatagg gttaaaattt tttacctccg gaggtaaaga tttttgactt ccagaattta
    15961 ttgatttgat aggcttttct aaaacagagt tttcatcttt caaaatagaa gattcttctt
    16021 cactgcctgg acgttcaatt tcaaataaga cacaaccttt gtaatctaaa gtttttacat
    16081 ggtggtagac tacagttcct ttgtcacgtc ctttttctac gacttcagca tcatagtgtt
    16141 catattcttg taattcagca ttcacatttt gcagatacaa acgattcgga cgattcttcc
    16201 cttgtttcac ttcacgaagc aagccaagct ctttcaattc tttcttgatt ttcaacacag
    16261 ttggcttact acgatctaaa atttccatta agtcctcaac cgtatagaca agaaatactg
    16321 aaccattctc atcaacataa gtcagttcac cgtttctgta agaataaata ctcaacatac
    16381 atcgatcata gagtacacca taagcaattt tgccatcatt tgataatttc ttggcataga
    16441 gactcgtcat cttgattttc ccagtaggtt tcccttcagc agaaaatttc ttcttaacat
    16501 ttaccatgaa aatttgtggg atttgataga aggtctgtgt tgccacttga tttactgtaa
    16561 tatcagccat gttatcacac ccccatcatc acagtaccat ttcccataga gaacagaact
    16621 ccttctctct ctaattcttc aaccgcctta acagcacgtt ttttactcat tcctgttttt
    16681 ctcatcactt cgttaacagc tgcttttttt gaaaattgca caaacatttc tttagtcatt
    16741 ctactatctc ctttttctgt ctcactaatt tgagctcctt tgaaaagcaa ctcggacatt
    16801 cagatagacc aagctgaaaa tccaaatggt caaataaaaa gttacatcgc tcacactgca
    16861 ctgtgcttct aagtattgtt tcacctaacc aatctctttc tacaacatct aatacatctc
    16921 tacattcagg acaatgaata ggcttgaaaa tattatcttc ttcccatttt tcctcataat
    16981 cacaatcaaa acaaacgatt gtttccaacc acatggatta actcccttcc aatgttcctt
    17041 ctaattcgcc tatcttgaac ttaaattcct tgattttctt tctcacaaga tcacgttctg
    17101 cactcattag ttgtacctca cttttttgta aggttttctt aagacttcta gtcttgcctc
    17161 atatagctcc agtgaacgct tataataatt caacatttct ctttctagtc ttgtcatgct
    17221 atctcggcct ctctcgtttc aaacagaagc aagtaactca ggagtaaatt ccatcgtcgt
    17281 ctacaggcct tcatcataag tcagttggct ggtttgtccc cattccccat gttccatctc
    17341 tagctcttct gaaatacgga taagtgccaa gcttaattct aagatataat tcatgaataa
    17401 catcatcttt tatgactttc cataaaatac tagcgagctt ataataatcg tttccaagcc
    17461 aaactctagc aaggtcattg tctggagata cttttcatca gaatttcctt cagaaataca
    17521 atcaaccata ttttcattct tatcaagatc tattacatcg aaaatttcta gcgaatcaat
    17581 atccataaca atttcaatat tatctgacat tttttctcct taatttttgg caacgaaaaa
    17641 agagaacgga ttttttcgtt ctctacattt atttatattc tttctgcatt tctcaaaact
    17701 ctagacactt acagttattt ttttgaaaag tttctgtttg tattttggtt tggttttcga
    17761 atcaaaaaga gagaatcaaa ttgattccct ctctatgtta gtttttactt attttcccta
    17821 taggaaagct aagacctatt aaaaacttcc tttttacgtg aacttcccca gctttcgata
    17881 aatagaatcc ccactaacaa aaggataatc aggcaaggaa gtaagaccat ccccatgctc
    17941 caatttagat cgacattatc aatctgctta gataatcttc cagataaaat ctccactgaa
    18001 cgcaagtaag taaagggaat cagatgtgca atcctttgaa gaggctgaat ggtttggatg
    18061 ccaaacaata agccaacaat cccaatgagt gaaagaaaga ggacaggcat tttttgcttg
    18121 aaaaagtaag caatcaagta cacaacttcc acaatgacga taaaggctaa gaaagctaag
    18181 agcaagccag gaaataatac atcttgtatt ttcccaatag ttacctcttg attcactaag
    18241 ctataaatcg ggtagggata atctaactgt ccaaaaccac ttatcagact tcccactaga
    18301 aaagaaaagc cacagattcc gataaacagc acagttacat atcccactcc aactccaaga
    18361 gaggatattg caaatgtcac ttttgaaaca ggatataagt gagctgtgtc cagatgattt
    18421 tgatatcttt ctgcaaatag ttgtgttagc ataaaaataa tcgcaaccac aaacaagctt
    18481 gggatgataa cctctaaaat ccagacaatc tgatcaatcc cgtgggtcgg aaactccaaa
    18541 gtatgtgctt ttatgttcaa gggatacagg gcttggtaaa tcttccgttc gcggtcaacc
    18601 cccattttta agccagagct agcagtcggg tcatttgata caaattcata attcttctct
    18661 tcatcttgcc actgcagata ataggcctct ttccagcgcc cttcttttaa taaagtcaga
    18721 atttctgtct ttcgcgtcaa aagatttttt tgcaagtcta aattattttt agcaaactgg
    18781 tattcctccg agctggtgtc agacatttgg gaaagtttcg cttcattttc attgatggct
    18841 ctcccgttat ccacaatgcg actttccaac ctactctcca agctgacgga gtttgcagtc
    18901 tgactattta aataaaaggt aacaccaagt acagatgcaa ataaaagtaa gacaatccag
    18961 tttaagcggc ttttgaaaac ttttttcaat aaaaatagac taacatcttt cataacggaa
    19021 cctcttctat ctgcccctga tgaatggtta ctactctatc gcagacatca accaactctt
    19081 ccttatagtg ggaacttaaa agaaccagct gctcttgtct atcgatttgt gcaagcctat
    19141 caaaaaactt ctgtcgataa tactcatcta agccatttgt aatctcatcc ataagccagc
    19201 atttggcctg actgaggaaa tacatggcaa tcaccaagcg ttgcttcatg cctaaggaat
    19261 acttgcgaat gggaaggctg atatagtcag acatttccca ataggcaatt tcatccctca
    19321 agttcaggtc tgacttccag atgtttttga taaggcgaag atagtctatc ccacttaagc
    19381 ttccatccag ccattcaacg ctctcataat aaaataaaga aggaggggct gcaatatttc
    19441 cgctacttat aggaattaaa ttgctaatgg tgcggaatag tgtcgtcttt ccagaaccat
    19501 tgatagcaag aataccataa atcctaccct tttcaaatgt aaaatcaaca tcttgtaaga
    19561 tgacttgtcg cgtttttaag gtcacatgag taagctgcaa catacctagc cctccttttt
    19621 atcactcttt aaggattaat agcctccgct gtagtagttt attacctcat aacgatcata
    19681 gttccagcct ccgccaactt tatactcaga atagctgtaa taacgagacc atgacggaat
    19741 atcactatat ctatgtctgt gataattcat actagactta tagaagatat tccaatcata
    19801 ccgataagtt ttaagaacgc tcacagcaga tacactggac tgaaaaagac caatagataa
    19861 caaactagct aataaaacaa cttttgctga tttttaatga ttttatatca tcaatatcga
    19921 agacgctttc attatatcgt ttttatcatt attatgcaac agatttttag tttattttac
    19981 taatatataa tatttgtcct tcctatcgaa cactttcgat tttccaactt ttccacccct
    20041 taaagcgtat agctccttgc tgatcagttc gataaacttt gctattgata gtttccagtc
    20101 gtgtcaatgt ttcctgatgg gggagtttcg tccgattact ctttccaact gagatgaggg
    20161 taatctctgg tttgagtttt tctaaaaacg ctgaacttga tgaggtttta gagccatgtt
    20221 ggctagcttt caaaacatcc acttctaggt caggatattg cctcagcaag tctctctctc
    20281 ctttctcctc caaatttcca gtgaagagaa attgcttatc caagagtttc ccatacagaa
    20341 ccagggtatc atcatgaccg ccatctccaa ttttccttgg ggataggact tctaactgac
    20401 ttccaaaaat tagaaggttc tctcccactg acacactacg tactttgttt tgagtcgcct
    20461 gtagttctac cacaaattcc ttctgtttca gactgccttt tgacactaaa atttcgccta
    20521 catggaaagc cttggtcacc tccaacaaat ctccaatatg ctccttgtcc gtatttgtca
    20581 aaatcagctg gtcaatcttg ctcactcctc gacttttaag atagggtatc aaggttcgct
    20641 gagcattgct ggtcgtcgcc ttttcttgcc atttttcgat tttcttctca gattctgcct
    20701 tgccaccaac atctatgaga atggttttcc cagttacatc ccgtaggaaa atactttccc
    20761 cttgcccaac atccagcatg gtgatttcat tttccagtgg atacttggtc aggaaaaaga
    20821 gacctgtaat caataagctc aacactgcta gccttttaat gtttttcctc aaatcataga
    20881 ctaaagccaa ggaaattaac aataaaatta aaagccacgc attaggttgt ccaaagacta
    20941 gaggcctact tgccacctgt gataccaagc gaatcatccc ctccaaccat tcaaaaataa
    21001 aattcagctg aatgactgga tagagaaagg aaagggcaaa taagatggac aagagcggta
    21061 agaagaccaa gtcaaataga aaggaaaaga caaaggtcaa aaggatagac caaggttgaa
    21121 attccgcaaa atagaaggat agaatgggca atatgcccaa ggagatgact agactttcac
    21181 tagcaacagc cttgagcccc tccccttctt tgctggtcat ggtcaggata aaagcataag
    21241 cgcaggacaa gactcctcct gctgtcaaga aaaagtttgg catgacaata aagaggacaa
    21301 gcaccgtcaa ggcaaaatta tccaagccct taaccccatg ttgagccagt agcttttgca
    21361 agagactgcg aataaccgat gctgaaaatc cagttagtcc cgcatagata agggaaaagg
    21421 gataagtcaa ccatttcaac ttttcttggg tcaagcccaa tcgcaagaga agtttcttaa
    21481 atccattcat gaaaaaacct acctgcatgc cagatagggc aaagaggtgg ataattccta
    21541 gactggaata aagctcattc atctcctcaa agtcggtgtc cagatgtccc agcaagagtc
    21601 ctgtcatgta attgcgcata gggtctggaa agtgcgtctt aatccaaacc acagcctttc
    21661 gacgtaaact ggacaagttt tctcctatat cccaactgcc aatcttttga agtgactgga
    21721 ttgttttgat attgagagtc tggtaaattc cctgagtctt cagataggct tggtaattaa
    21781 agccaccaaa atttctctgc ccttctggct ccgaaagctt cccttctagt cctatctcat
    21841 gcaggtcggt taaagcttga aaggcttctt tctcctcctc ggactggagt ttataataga
    21901 cttggaaagc acgaccatca gacttaccac gaaaggacag actgtcaccg ttgaccttaa
    21961 tagtgtctgg taaaatccgt accctttcaa cagaatccgc cagattttga ctcgcttgac
    22021 tctgttgcca agtttgaaac agaaaccaga agccaaagac tccacaaatc actagaactt
    22081 tacctgctga tttccaagga aattggataa agaggcagac tagcagaaaa acaaaaccca
    22141 acaaagcaaa ataggatact gagaaaatgg cgtagtaaag ccatagtaac agaaaactca
    22201 ggtaaattag gggaatagag aaattcttaa tccactgtaa catagtcttt aagtttttct
    22261 atggtcttgg caccaatgcc agagaccttc ttgagctcgt ctactgactt gaacttgcca
    22321 tttgcctcac gatggtcaat aatgtcctga gctcgttttc ctcccagtcc cttgacctgc
    22381 ttgagttctt ccagactggc cttgttgaga ttgaccttct tttccttgct tgttgaagaa
    22441 gctgtccccg aaccagtctg ttgactaact gcttcttctc ccttagtagg aacgtaaacc
    22501 agagcctcat cactaacttt ctgagctaga ttgagcgact tgctgtctgc ttgctctgtc
    22561 aagccaccag ccttctgaac agcatcattg actcgactac ctacaggcaa gtcataaatc
    22621 cctggcgatt tgacagcacc tttgacatct actgtgatta gatcttgttc aactggttct
    22681 tccttctctt ccttgttcac ttccttttcg gataccaaat ccttggaaac agctgcaact
    22741 tcagcctgca aattcgtttc ctttacaggt gtttgtggag ctggctttag caggaaaaat
    22801 ccgcctacaa gcaagcccag accagtacag atgacgatga ttttatactc tttgattttc
    22861 tcgataattg cttccatatt ttctcctctc ttagattatt cgtaagagga agaaaaaaca
    22921 gtcgaaaatt tcttttcaac tgcttattta tttgcaaaat agtcttcctt ggtcaagaca
    22981 taatgaactc ttgtcacgat tcggcctttt tcatgctggt ccatacaagc atatggttct
    23041 gcatgggaaa aacgcatgcc tgatttctcc atgacctttc ctgacgcagg attgtcctta
    23101 tcgtataaag caactaactt attcattcct atcttctcaa aagctagctc aatcacagca
    23161 cgattggttt ctggcgtcaa tccttgattc caatactttt tattgataat atagccaata
    23221 gctgccttct taagaacagg gtcaatcttg tgtaagtcaa tagttccgat aaacttgccg
    23281 ttatctttta attcaatccc ccaacgtccc aagggattag ccaagtagaa ctgagcaatg
    23341 ttattcttgg tttcttccaa gatttgattg gttggaaaag tgtaacgtgt attacccttg
    23401 tccgaggtat agtcaaacat tgcttccgca tcatccaaag ttacaggtct aagcaataaa
    23461 cgctccgttt ctatagacgg atactgggca aatttcacaa atattgattc catacttttc
    23521 cctccattag agcttgattt tcactagtct agcataaaaa aatttggatg acaagttttt
    23581 cttgattttt gaagcggttt catatacaat gaaaccgtca catttttgat ttatgaactg
    23641 gaatgtgaca accaaaacaa gaccgtcaat tgaaaggtag gttatctcaa tgttaatcgg
    23701 aatcccaaaa gaaattaaaa ataacgaaaa ccgtgtcgcc ctcacacctg caggtgttca
    23761 tagcttagtt agtcgtggtc atcgtgtcct tatcgaaaca aatgctggtc tcagttctgg
    23821 ctttactgat gctgactatc aaaagcaagg agctgagatt gtcgctactg ctggtgaagc
    23881 ttgggcagca gagttggttg tgaaagtaaa agaaccttta agttctgaat acggttactt
    23941 gcgcgacgat cttcttctct tcacctactt gcacatggcc gctgctccag aattagcaga
    24001 tgctatgtta gcagcaaaaa caacaggaat tgcctatgaa actgttcgtg acaatcaagg
    24061 acaactaccg ctcctcgttc ctatgagtga ggttgcaggt cgtatggctg ttcaaatcgg
    24121 agctcacttc cttactaagc aagctggtgg ctctggtgtt ctacctggtg gtgtaccagg
    24181 tgttccaaaa ggaaaagtaa ctatcatcgg tggtggtgtc gtcggtacac atgctgcccg
    24241 catcgccctt ggtcttggtg ctcaagtgac tattttagat attagtgcca agcgtctctc
    24301 agttctagaa gaagtctttg gaagtcaaat tcaaactctt atgtctaatt cattcaacat
    24361 tgaagcaagt gtgagagatg ctgatgtggt gattggagcc attctcatcc ctggtgcaaa
    24421 agcaccggaa ttggtgacag atgagatggt caaacaaatg cgtccaggct ctgtatcgtt
    24481 gacgttgctg ttgaccaagg tggcgttatc gaaacagctg accgtgtgac aacgcacgat
    24541 gaacccgtct atgaaaaaca cggtgttctc cactatgccg ttgccaatat ccctggtgcg
    24601 gttacccgca cttcaaccat cgccctaacc aatgtcactc ttccttatat cgaagctttg
    24661 gctggcaaag gattcgcaca agcaatctct gaagatgaag gcttgcgtca aggtgtgacc
    24721 acttatcaag gttacttgac tagcctacca gttgctcaag gacttaatcg tgactacact
    24781 gatatcaatg atttagtata aattttgaaa agaaaagggt gacttcacaa gtcctaccca
    24841 ctgtgctttg tgtcatcagc tattacatcg ttggtttatt gtactgtata ctttgaaact
    24901 ggagactttc gttccagact caattgtgca taagaaactc taaattgaat aaagtcaaca
    24961 gagtttcgcc caaccacttc gtcttgtaat gacaattata taaaccaaag gaagctgagc
    25021 tctttagtcc cagcttcttt ttatatataa aattttaccc gtgcaaagac agggccttag
    25081 cagacttctt ttttacttcg ttcacccttg ctttttcttt ttaggtttgg gcgttggcag
    25141 ttggttatac atagctaaaa tcaggtctta tagaaacatc ttattatcaa gttcttccac
    25201 tcaaatcatt tctttggcac ctttgtatgg aaactcaaaa gaagattggt caatcttatc
    25261 taagactgct tgcacgggtt taactaaaaa gcgatcgtca taaatgccgt caataatctt
    25321 gccgcggaag taaagaatat actcccccat catggaacgg taagtcacat catctaatcc
    25381 tgataattgt tccaaaacaa attccaaata gttcttactt gatgccattt ctaatcttct
    25441 aggctctgtt caacgataac aaccgtatag agttcttgct taacctcgca tccaattgat
    25501 ttaaagccct gcttttccca aaaatgctga gattgcggat ttcccttaac ataagccaaa
    25561 catgcctttc gaaagttctt agcaaaataa gctagtgctt ctgtcacaat atgactacca
    25621 atccctttcc tctgataggc ttgatcaacc ataaacaaac caataaaaac agtctcctca
    25681 tcaggatgtg catagacaaa atccataaca gccacaaggt cagatccatt ccaaaatcca
    25741 ataaaaaact tatcagcctt agctttacct tcaggtagac aaagcatgtc ctcttttaca
    25801 gttgcaaaat ttggctctgg tggacaatgc tgaaaataca gaggattact ttcatataaa
    25861 gataaaatac ttggaatatt cttttcagtt agtatcctac aactgtaata cttagatagt
    25921 tggtcaatca tcttttcaaa ttcctacttt cttgtgccct gtgattatga cacaggaaga
    25981 tgcactgatc gtcatcagcc acataaaagt tctttccatc gtgcctaatc gttgtctcaa
    26041 acctttggat aaaaccttta gcctatacaa ctggattttc ctctctcaac agtatattct
    26101 tttgcaggcg aacttcctca aaatcagtcg tgtgcaactt cagtagaata ttcataggct
    26161 cggataatct gagcgacaac tggatggcga accacatcct tggctgaaaa atgaacaaag
    26221 tcaatctgat ggatgttctt gagtttctct tgagcatcaa tcaaaccgga cttgacatta
    26281 cgtggcaggt caatctgact gatatctcca ttgacaatca tcttagaatg aaagcctaaa
    26341 cgcgtcaaga acatcttcat ctgcatgatg gtcgtgtttt gcgcctcatc gagaatgaca
    26401 aaggcatcat ccaaggtccg gccacgcata taggcaaggg gcgcaatttc gataatttca
    26461 cgctccatga gacgagtcgt ttggtctttc ccaagaattt gatacaaggc atcgtaaaca
    26521 ggacgaaggt aaggatccac cttctcctta agatcacccg gaagaaatcc aagactctct
    26581 cccgcttcca ccgctggacg agttaggata attcgcttga cttgcccacg tttaagggca
    26641 gtcactgcca aaataactgc aagaaaggtc ttccccgtcc ctgctggccc aattccaaag
    26701 gtcacatcat gctgtttgac actgtccaca taaagctttt gccctagggt tttgactcgg
    26761 ataggcttcc ctgtattgtc cttgatgatt tcttcttcgt aaagggcgac aaacttgtcg
    26821 atttcatcat ttttgaccat actaatagcc gtcactacat ctggcgtacc aacggtcatc
    26881 ccacgattta ccaaggccat gagagcttga ataacctgac gggcttcctc gcaagcagac
    26941 tcttctccca aaacctggac aatctccgta cgagcatgaa tcacaacatc aagctcttct
    27001 tccatcaaac gaagatggcg ttcattggaa ccaaaaagat gaaacaggtc atctggatga
    27061 ctcagttgaa tgtctattga atgttccttc aaataaagaa cctctctaat ccttttattt
    27121 ctttttatta tagcagaggg atggagaaat tactagtcca aacccaatga ataaatgcta
    27181 gtgttctaga tattcctgcc aaatgctgtc aaaatctcct aggttaaaag agaaactggc
    27241 atgctcctcc aaaaagcgac tgacctcatc aaaatcatct gtgtgttttg gaaaagctgc
    27301 ctcttcaaaa gctaggtctg ccaagatagc tttgggactg ttacttttag gattgcgctc
    27361 ggtcatgagc caagtgtaaa atgattttct cataaatctc cctaaatcaa ctctgtccca
    27421 aactggtctt gcttgatttt accagccttc ataagaccac ctaaagcttt cttgaactga
    27481 cctttagaaa tgccaaaggt tgccttgatg tcgtctggag atgacttatc atttaaggtc
    27541 atgaaaccgc cattgctttc caaataagtc aaaatcatct gagcatcgtt ttccaacatt
    27601 tcaaaggagc gtggtttgag ggagaggttc agagtgcggt ccacttcacg gaaaccaata
    27661 acgcgcgcat ctaatacttg ccccaaacgt ggctctgcgt aacgctcgct aggatgaata
    27721 aaaccaagca tattattttc tggtaggtaa acaaaagttc ctgacagctt gagacggtaa
    27781 acaatggctg gccagttttg gttctgcatg ttgttgtaag caggacgagc gagacgttgg
    27841 aagtcttctt gataagccaa gaggccccag atacggtctt tcttatccac ttcaagacgg
    27901 atgtagagtt ggtcgccctt cttaggccag agttccttga gctcagggag aatatcgagt
    27961 gacacaacga tttccttgtc aggaaggcct gtatccacaa agacacccaa gtccttacga
    28021 acctctgtga cacgtcccca accaaattgg tcctgagtgg cagtcacttc taaggttgtc
    28081 aggcggagtt tttgcttcat atccgtgtat gcaaaacctt tgaccgtatc ccctactgta
    28141 tgttggccct cttccttagc aagagcatag gtttgaccat ccttttgcac aaagtaaaaa
    28201 cggtcatttt catcgatgat cagtccaacg ataaaacttg caagatttgt attcatattt
    28261 ccttctttcg aataaaactc agccagcaat gccaactgag tttttctgtt tatttttaga
    28321 cttccaaaag ttctttctct ttgttggcag tcatatcgtc gatgtgttta acagcatcgt
    28381 ctgttacttt ttgaatgtct ttttcaagag tcttcaattc gtcttcagtg atttcttttg
    28441 ctttttcttg tttcttagct tcgtccatag catcgcgacg gatattgcgg acagccactt
    28501 tagcattttc gccgaccttc ttcacttctt tagcaaggtc acgacgagtt tcttctgtaa
    28561 gaactgggat aatcaagcga atcacagaac cgtcattagc tggtgtgata ccaagatcag
    28621 aagcgttcaa ggcacgttcg atgtctttca atgaagactt gtcaaatggt gttaccaaca
    28681 aaacacgcgc ttctggaatc gtaattgaag cgatttggtt aagaggagtt tcgactccat
    28741 agtattctac atgtacacgg tcgagcaagc ttgcattggc acggccagca cggataccac
    28801 caaattcacg agcaagtgat tggtgagact gggtcattct ctctttagct ttttcaataa
    28861 ttacgttagc cataatcttt cttcttcctt ttcttagata ttatttgaaa ctgttgttcc
    28921 gatattttca ccaaatacga cacgtttgat gttgcctggt tggttcatgt tgaagacaac
    28981 caagtcaatg tcgttatcca ttgagagggt tgaagctgtt gagtccatga tacgaagacc
    29041 tttgttgata acatcacggt gggtcaattc ttcaaactta acagctgtct tatctttctt
    29101 aggatcggca ttgtaaacac catcgacacc atttttagcc ataagaatgg catccgcttc
    29161 gatttcagct gaacgaagag ccgctgttgt atcggttgag aagtaaggtg aaccaattcc
    29221 agcaccaaag ataacgatac ggcctttttc aaggtggcga agagcacgtc cacgtacgta
    29281 aggttctgcc acttgttgca tagcaatggc tgtttgcaca cgcgtatcga caccaacttg
    29341 ttgcaatgaa tctgccatca caagagcatt cataacagtc ccaagcattc cagtgtaatc
    29401 tgcctgaaca cggtccatac ctgcttctgc tgcaggttct ccacgccaga gatttcctcc
    29461 accaataaca agggcaattt cgatacctaa gctatgaact tcttgaatct cttttgcgat
    29521 tgtttgaact gtttggatat caatccctac gccacgttca ccggcaaggg cttcacctga
    29581 taacttgatt aaaatacgtt tatacttggg attcgccatt ttcactctcc ttctttcatc
    29641 ctacctattt tatcacaatt tctaagattt ttatagtatc atgagcaatt ctttcaaaaa
    29701 aattagacag tcaaaaattc ctctaagtcg gcaagggcac gctctgcaat tttttcataa
    29761 cgagccttct tatcacggat acgctcgcct tccaactcct tgatgatccc aaaattgaca
    29821 ttcattggtt ggaaatgttt gctgtcggca tgggtaatgt aatgagctaa gcttccaatc
    29881 gctgtcgtct cggggaaaat aacctcgctt tcttccttga agagacgagc tgcgttaatt
    29941 cccgcaacta agcccgaagt cgccgactca acatagcctt ccacccccgt catctgacca
    30001 gcaaagaaga gatttggttg tttcttggaa cggtaagtct gctcaagaag atttggtgaa
    30061 tccatgtaag aattgcgatg catgacacca taacggacaa actccgcatt ttcaagaccc
    30121 ggaatcattt ggaagacacg cttttgttct ccccatttga ggtgggtctg gaaaccaaca
    30181 atattgtata ggctaccagc tgcattatcc tgacgaagtt gcacaaccgc ataaggtgtt
    30241 ttaaattctc catcacgagg tcctgtgtag tcgtccggat actcaagacc gactggcttc
    30301 atagggccat aaagcatagt tttaatgcca cgtttggcca taacttcgat tggcatacat
    30361 ccttcaaagt acttttcttt ttcaaaagaa ttgagcggtg cttcttccgc attgaccaag
    30421 gcttcatgga aatccataaa ctcttgcttg gtcattggag cattgagata ggctgcttct
    30481 cccttatcat aacgagattt gagatagacc ttactcatat cgatagtgtt gacatcgata
    30541 ataggcgctg ctgcatcgta gaaatagaag ccatcgccat tattaagggc atgaatcttt
    30601 tcagccaggg catcgctagt caagggacca gtcgccacaa ctgtaataac atctgttggc
    30661 aattctgtaa tttcatcacg caccacttca atcaaggggt ggttgaccac tttttcggtc
    30721 accatttgag agaaaccatc acgatccacc gcaagggctc caccggcagg aacacgtgta
    30781 gcctcagcag attccaagat aacagaaccc aagcgacgca tttcttcctt gagaagacca
    30841 actgcatttg tcaaagcatc cccacgcaaa gaattggaac aaaccaactc agcaaaattg
    30901 tctgttttgt gctgaggagt cgacttgaca ccacgcattt cataaagttt aactggaata
    30961 ccacgctctg cgatttggta agctgcttca gaacctgcca aaccagcacc gataacattg
    31021 atataagatt gagacacgac actaatacct ctttgggagt gtgaagttaa gattcacatt
    31081 gaaaaagcca atcagactta cgagctttcg agtttcttgg ctcaggctga aaaagtccat
    31141 tggacttact tcgctctcga atttcttggc tcaggctgaa aaagtccccc agactttcct
    31201 cgctctcgaa tttcttggct caagctgaaa aagtcccccg gactttttca ctcccacaaa
    31261 tctttctatt tttttcttct actagtataa caaaaaaagg gaagaaggca aacttccctg
    31321 tttagtcatt ttcttgatgt aaagagatag agagtattcc agttaagaat caattatatg
    31381 ctactctata aaatcttttc cacataacgg atcgataggg actgttattc tatctcttgc
    31441 tataaccgta ttatctaaaa cagcataaca ttcaacatag tggtctcctt taaactgaga
    31501 atcttcgtga tgttttattt tacctgaaaa aatagcacca cgctcacaat ttcttctaat
    31561 cgcctcagct ccaatatttc tcactttcca ataatattta acatcagaca aaagattatc
    31621 tggaatatct gattttataa tttcaaaatc aagagatttt ctatttttaa tcttaaatct
    31681 actttttaaa aagtctgaaa gaagtgcttt tcgaaaacca tcttgtgtaa tttcacactc
    31741 caaaacaata ttatattcga tattaacatt aaacaattca tcaataaatt cttcattcga
    31801 agctcgattt gttgtagaag tagattgagc gaattttcta ccaaatagct gtctataaac
    31861 ttcagtaagt ttctcttctg aagcgtcttc tattttcttt agagcctgct tagctttatt
    31921 gacaaatttt gctccatcat tattataaat cttttgatta ctacctaaag cataccaata
    31981 ctctctattt ttatcttgat ttgaaaagta ttcaaaaata tctttcaaga gaatattata
    32041 atcagaataa tatatttcag aaataccttt atcatcaatt aaatcagata tcaaagtatc
    32101 tatcaacaac cccttaaatg aaaagcccat atgatttttc cattgtcgta tgagccttgt
    32161 taagttagaa aaatgactat taaaattgga atttaaagat ttgcattttt caatttcaaa
    32221 ctttggttta gtagttttcc aagagcctcc gttacgagaa tcaggatatt taaaattacc
    32281 atcagatttt tcgaaagctg gaactaactc aatttttcca ccatccgaaa aatcaataac
    32341 aacgacctgt ccgtctcctt ttatttttgt atttgggtat ctttttagta attcgttttt
    32401 tatttcctgt aggagtgctg attgaccatt gccctcataa gaatcaaatc gtctatacac
    32461 ttctgatggt agagaaaaaa tataatcaaa atcactaaca tttcgaacag ccgtcgttct
    32521 ccccacacta ccaacaatca aaccgttgtc agtttcttga tcgtcaagct catctaagga
    32581 ataaaatttt cgattaagtc gtttcgtaat ctcttttaat ctattctccc atttttccca
    32641 ttcctcatcc gtcatgggga gttcgtcttc gcaaaattct ttaaaatcat tagataaaga
    32701 cattactctt cctccttaat ttccatcaat tcttttggaa taaagtatct ataatcctcc
    32761 tcataatcat tatcttttct cgattttatt agttttgaag ccttggatac atttttggga
    32821 gaagcattag aaagttgact ataagtagca tctcttcgaa attttaattc ttcgaaaaat
    32881 tcttggattt cactggatgg ttttccattg taaaccacct cagataaaag aatttcagct
    32941 aacactctaa gattccaaag ctcatcaaca gatttcctct ccaaagctag tcgttcctca
    33001 aagttaaact cctttgtgat gctaaaaatt attgtcgtga ctaatgataa aaatgctgta
    33061 acaagcttta tccaatattc atcaaaccaa agtattccaa ctaagccaga agagacaact
    33121 ccagaaatga ttattgttgc tattctaaac catcgaatat agctttctaa ctcgtcaatt
    33181 ctaaccgcat gaattttgtg agtccaacct acatttacta taaatttttt aagttgaaag
    33241 tgtaattttt cttgattttt cgacattaaa tctccctcct ttactatttt tgcttatctt
    33301 ggtatgtttc ccaaacaaat gacactaccg ttaatgcaga acctacaaca actgaagcat
    33361 accttggtgg caattctata aagttagctc ccttaccatg accatcgcct ttatcatttc
    33421 taagattgtt aatacccttg ataatttgat tcaaaccact tagaaccacc ttcacatctt
    33481 gattattttt tgctgaaata ttttcattag aatccaagtt taaaaattta aagactttct
    33541 tttgcaaagt tgcaatatca ttagaattag aatactcaat tttttcatgg tctaaaatat
    33601 gtttaaaaca cgattccaac aattccttag cttttccaat agcgtccgct ggagagcgag
    33661 aaatcatttc attcataatc cccatttgct tatctatata gtcgctatca aaatagtcag
    33721 ataaagattt agcagcatta tttaagtagg ctatttgtga gacttcatat ttcgaaagtc
    33781 tctctttcaa tttcaatgcc tgagagttcc tctcttcagt tttctcgtaa tatgagtcag
    33841 gaaggtcttc ataatatcta agtaaatcta aagccaattt taaaaccagt tcatctggtt
    33901 cgttatctac aaaagcctgt aaagctttcc cttttgaacc tccatatttc tcttgaatat
    33961 ttactcctac tgaattaaaa gtaaaattag caaaagtaga gttagaaaaa tttaatacat
    34021 aaccgtcact attaaaaaat acttttataa aactcttatc ttgaaaattt aattccatat
    34081 caagttccct agatttaaaa catcaactcg cttcaaacaa atccagttga ccaaaacttt
    34141 cttcgagttt ctgttgcttt gcaattacat cactatttcg taaatctgac actaactttt
    34201 cagcaatata ccacatcatt actggtggaa tagcattccc cagcattcta tattgagcac
    34261 cttctgaacc aagcaattca tagttttctg gaaacgactg aatacgtgca acctctcttg
    34321 gagtatagcg acggtaacgt ccattttcta acaaaacagg gtcagtgcta tttaaggata
    34381 cttttgctaa gtgagaacta accgtattac tcggctgttc aatgtcttgt gctcgtcctt
    34441 tattcatttt tttgccagat ttactattta gcattccttg cacagccctc tcactaaaat
    34501 aatacttttc atcaatatct tgctgaagaa ttacttttag tggtgtataa tcttctacat
    34561 tttgaatagg ctcttcagga aattcaaaag taaaattcaa atcctttcga ataccaacaa
    34621 taaacacacg ctctctcttt tgcggaacgc cgtatttggt ggctacgcaa agtttataag
    34681 aaacattata accagctttt tcgaactctt caataattag aggaaaggct tctttattgt
    34741 ttgcagacaa aattccctta acattttcgg caaaaaatgc ttttggttga tgagctttta
    34801 acactcgcac catctcaaaa aacaatgtcc ctttttcgtc ttttattcct aagcgtttcg
    34861 gattttgagc actaacagaa aatgattgac aaggaaaacc tcccgttaaa atatcgaaag
    34921 atgggatttc atctgatttt atttctcgga tatttcgatt gtctggagta acaccaaaat
    34981 tcttttcaaa cattttattg gcactgtctt caatatcatt tgcatagaca atctcaattt
    35041 gattgtcggc ataatgttta cctaaaaaat caaatccacc agcaaaacca atatccgttc
    35101 caccccctcc actaaaaaga gaggcaattt ttagtttctt caaattaaat tctcctcaaa
    35161 gccaactgac gatgaaaaac gggcatcata tccatctttt ctctcaatca gaagcatctt
    35221 ctcatttttg actaactcat acaaattctt gataataaac aattttttgc tatgtttaga
    35281 aatctgcaaa cgataaatat agtatctatc acgcacagat ttagcagttc gccattcgtt
    35341 tggtgtgata tgaaacgaat taaaagtaat agaagcattg ctgacagttg ttttgacttc
    35401 aatatacttt ctcagctcag aatcatcaca ctcaaaagat tgaacatcgt agccgacacc
    35461 aaactgtgtt ggaataaaat tcaccagatg gagcaactgt tcttgcccat gttctcgtaa
    35521 tttttgtttt tcatgattga taacaatagc ttctcccgaa ctccctacaa cagcggtaga
    35581 tattttctcg ctgtattcga tgtgttcagt tagatgtccg ataatatctg ttttctcttc
    35641 agtaaaatca atatcacttg gaaggtagag attaaagttt gtcctaaaat caatatctcc
    35701 taaatcacga ttgacatatt cgaaccaagc acttctaaaa tttcgaacat cttcaattgt
    35761 tgtagaagca tttccaataa attgagcata gccatcaaag gtagcatctg attgcaaaaa
    35821 gtcatttgtt gcttgctctt ccatagaatt tattttatac ctaccacctt gaacagttag
    35881 taaactcgct ataaccatgt aatctaaaac atctttggca tatcgaataa catctccttt
    35941 agtatcgtaa gctactttag acgctctatt ctctttgata cgattccata tttccaaaac
    36001 aggctctcta tcacgagtac atctcaaatc attaaagata caatgggcga cttcttcatc
    36061 ggtgaggtaa atagtttttt cttcagcttg tgaggcttct gtaaatagtt ccagtagata
    36121 ctgagctggc ttaaattgaa ctccgatttg acaaagttta acaatctcgt tatcttttag
    36181 atgcccacca gtatattcaa aattatacaa aaaggtttta aaaaagcgaa taaggtcttg
    36241 gtcttcagtc aattccttag ccctatttcc tgaatagaca aagccttctt tctcaatcat
    36301 cattccaaac aaagaagaaa tctctgttcg ccagttattg attgttttct ctgttttatc
    36361 tgcatttcct gcatattgtt tgataatgtc atttagttgc tgactaaatt cctttttagg
    36421 caatattccc aaataagaaa tattcgttgc catataaaca agtacatttt cgacatcatt
    36481 tttaaaacga ggtcttgggt gatgtagtct aaaataatat ttctctggaa cttgatacat
    36541 agttactctt cgttattttt taaatatttc agtaaattgt ttgcaatctg ctgagccatt
    36601 aaaggaggaa cagcattacc aacttgtcta aattgctgtg ttttacttcc gtaaaagata
    36661 aaatcatctg gaaaagattg tagacgagca gattccctca ctgttggcac acgattatac
    36721 ttatagtgga aatgatgtct atgccccgta tcaatcgtag gagctggctt ccaactagca
    36781 aatcgtgtcc aagcgacatt aaattttctt gtttctcgta attccttcgg gagattttta
    36841 taatttccac cgtcagggac aagggcaatt gtacttatca ctttttctga atgcttggct
    36901 gcaacgtggt tcaaaactac gtttgaacgt tttcgcatta gtttttgata gtcattttgt
    36961 ggttctgaaa cataagacat ttctatctcg ccaagttcat tttctaatgt tggtaaatca
    37021 gaaattgcca tctctgttgt aatgattgtt cccaatgctt caggatattc aaatccatca
    37081 ttcctcgtcc ccacaaaaat aacacgtttt ctattttgag gaactccata gtcagaggcc
    37141 agcaacactt taaactgaac cttataaccc attttcgaaa attcttctat gatagtatct
    37201 tttatttgcc ctttaaacaa actaacaatc ccaatcacat tttcaatgac aaaagcagtt
    37261 ggctgtattt ctcgaaccaa tcgaatataa gacaaataaa gtttgttcct tggatcatca
    37321 aatcttctag gtccagaaag cgacatcccc tgacaagggg gaccacctac aattatgtca
    37381 attttttgtt ctccaattat tggttttata tcttcctcat aagatatatt cgcaatatct
    37441 ccacataata tttctgaatt ctgatgattt ttttgaaagg tttctaaggc tttttcgtca
    37501 ttatcaattc ctaatagaac attaaatcca gccatctcga atccataaga tagaccacct
    37561 gctcctgaaa ataaatctac aatgttatat tttttcaact gataaactcc acactatttt
    37621 ctcatatata attataccat actgcgtact taaaaataat tctaatagag tacattatat
    37681 atattcaacg taaactgaat gaacattgtt tttatttatt cactactcaa tcaattctat
    37741 tatttagact ccgaatatta tcatcactaa ttaagttaaa cagaaacaga cagaattatt
    37801 acatcctgtc tccctttatt gtttttcttc ccagtcgtgg taggctgcgt agagttgact
    37861 cttattccac tggtaaatct tagctacttc cttaatagct tgatttttct tcataccttg
    37921 ctggatacga gcttggattt ctaagaacaa gtcttcctcg tctttttctt ccacatcctg
    37981 actggcacct tcaacaatca gaagacattc acccttgaga gacgtttcag agatgctttc
    38041 cagcaattca gaaattgtac ctctttggta ttcttcatag attttggtca attccctgac
    38101 caagacaacg gagcggtcac cgtagacttc taacatattt tccaacgtgt ctgctacacg
    38161 atgaggtgat tcatagaaaa tctgtgtttc aggataatct tttttcgagt caaaaaattg
    38221 cttctgctga cctgattttc tcggtaaaaa accgtaaaag atatgtggct gtggagctaa
    38281 accactggca atcaaggcag aaattcctgc agaggcacct ggaacagtca caactgcaat
    38341 ttcttcctca atagctgcct taaccaaatc atgaccaggg tctgaaatgc taggcaaacc
    38401 ggcatcagag acctgagcaa tactttgccc tactttcaag aaaccaatca aatcaggaat
    38461 tttttccttg gcattgtgct catgaaaact gatctgcttg gtggaaatgt caaaatgctt
    38521 gagcaaaaga cctgtattgc gcgtatcctc agcagcaatc cagtccactt ctttcaaggt
    38581 ctggatagcg cgaaaggtca tatcatctag attgccaatc ggcgttgcca ctagatacag
    38641 cttgccatag ggagactgcc ccttaaaact tttttgaatc tgcatgctta ctccctgtat
    38701 aacaactcgt cacagaacat acattcctcg tcctgttctc gacgttgtcc ataaaaatca
    38761 ttacatacgt gaaatccatc acggtaaatg cgacgaacac tttcgcgaac atgcttggcc
    38821 ttgacgggag cgtctgcttc cacctcaccc aaacgttcgc gcaacttaga attttccaaa
    38881 cgaagagctg tattttcctc tactaggctc ttgagatttt tcttgatagc ttccacatcg
    38941 gccaaggtta ccaataactg ttgggaaaaa tcatccagcg cgtcaaataa ttcttttttg
    39001 tccataagcc aggcctttcc tttctttatc gttcattttt gagtttatat ttctttcaag
    39061 accagatatt ccatggcatt ttgaaagctg acattagctt gccacatttt tctagcttct
    39121 agcaaatctt gtagaatcac ccttactctt acctgcaaga ggtcctgccc acagagaact
    39181 tcaagaaccc gtaaaacctg atcttgtttt tccttatcat ctgccaagtt cgctaatttg
    39241 gcaacctgta gataactttc ttttttctta gctactaacc aagtcagcag gcgttcactt
    39301 tcatcgacca aggtccaaaa acttgcctga ttagccaact tttctgcttc agctcgcgat
    39361 tgactaaact gagctaaaag agtcgctttt ttcttaacaa gtcccatttg ttctaagagc
    39421 aagatgagtt gttcttcttg ctttttaaag tggaaaatct gggtccgact tcggattgtc
    39481 ggtaacatct tttcctcatc gctagtcaag aagaaaatat aaacttcact ctggggttct
    39541 tcgatgacct taagcagaga attggctgcg ttgggatgca ttttatccgc ttgctcgatg
    39601 ataaagacct gttgctggct ttcaatccct gcttgagaaa actgtcccac caattcccga
    39661 atgcgttctg tcttgatgac ctgattgact ggcttaatca aggttacatc tggaaactct
    39721 ccctgttcaa tcagcttaca atttcggcag ttttcacatg gtaaaacatc taccttatcc
    39781 gtacaaaata gactcttggc caaaaactgc gccatttcca ggcttccaaa gaaacctgaa
    39841 aagaaatagg cgtgattgag ctggtcttgt tctaagatac ggacaaatcg gtcaaactgg
    39901 gctggttgcc aagcctttaa ttgttcttgt ttcatttggc caagcccatt ccgtcaaaca
    39961 agacagcctt ggtagtttcc acaacttgct ccaaagggag actagcatca atcttgacaa
    40021 tgcgatttcc ctctttatcc agaagagaaa ggtagccttg acgaactttt ttatgcaagt
    40081 ccaacccttc caaatccaaa cgattaacct cgcggtcact attagcagca atacgagcca
    40141 gtccttcttc cacctcgatg tcaaaataga gtgtcaaatc gggtttgagg ccatctgtcg
    40201 caaactgatt gagccagtca atggcttcaa tatctaagcc acgaccaaat ccctgatagg
    40261 caacagaact atcgataaaa cgatccataa tgaccagctt gccagcttca agggctggaa
    40321 gaactttttc caccaagtgc tgtctgcgac tggcaatata gagaagcaac tctgtcttcg
    40381 catccatctg agtatgactt ggatccaaaa ttacttcccg aatcttctcc ccaatcaaga
    40441 caccgcctgg ctcacggctc gtcagcacct ctactccttt ttcctctaaa attagtagta
    40501 gagcctctaa aacactggtc ttgcctgctc cctctggtcc ctcaagagag actaaaaatc
    40561 cttttgacat gtctaactca tttctttttt actacttcta ttctatcaaa aaaatagggg
    40621 tttgtgacaa tctttttgtc ttctcatttc atactcaatg aaaattaaag agcaaactag
    40681 gaagctagcc gcaggctgta cttgagtacg gcaaggtgaa gctgacgcag tttgaatttg
    40741 attttcgaag agtatcaacc accataaaag aggcagataa aactacctct tattgaccta
    40801 gttcttgtgt tcgtttatat gcttgatgaa ctgcatccat gaccgttcct cgaaaagcat
    40861 gcacttctag gcttgctacg ccggcaatag tcgaaccgcc tggactacaa acttgatctt
    40921 tcaaaactcc aggatgttgc tggctttcta ggaccaattg cccagctcct accacagttt
    40981 gggctgccat tttcaaggct gtttctcgtg gtaatcccgt ctgaacaccc gcatctgcca
    41041 aggcctcaat aaagagatag acaaaggctg gtccacaacc tgcaagacct gtcgctgcat
    41101 tgattaagct ttctcctaat ccaaccaaga gaccagcctt ggctaaaagc tgacaaaaga
    41161 gctcactgtc ctcagcccgg caattaggag acaaggcata actaatcact ccttgcccga
    41221 tagaagcagg ggtattgggc atcatacgaa taattcggtg ttgacttggg ataagacttg
    41281 ctagtttttc taaggtcaat ccagctgcca tcgaaatcaa aagaagactt tctctttttt
    41341 caaggatggt ctggtattga gaaagcagtt cagaaaactg agcaggctta actcctagaa
    41401 aaatcacatc tgcttctgca aacatttctt cattgctgga agcctgacca ccaaagtctg
    41461 caatgaaagc atctaccttg gcttgactac gattggcaag gagaagctca tctgacgtcc
    41521 tagtctgcaa gacagatttt gccaagctag cacccatatt ccccaaaccg ataaatccaa
    41581 tcttcatctc ttactccctt atctgcccat caccagcaac cacatacttg tagctggtca
    41641 actctttcaa gcccattgga ccacgcgcgt gcaatttctg agtagaaatc cccatttcac
    41701 aaccaagacc aaattgtcct ccatctgtga aacgagttga ggcattaaca tacaccgctg
    41761 cagagtccac ttgatctgta aagtaagctg cagcttcagc attttccgtt acaatggcat
    41821 ccgaatgatg ggtactgtgg gtttcaatat gggtaaccgc ttcttctaaa ctgctcacaa
    41881 ccttaaccgc taggacatag tctaaaaact cggtgtcaaa gtcttgtgct tcagctactt
    41941 gacctgaaac aaactgactt gctttactat ccaagcggaa ttgaattggt tccagtccaa
    42001 cttccttacg ctctgcaacc agcatttgat ccaagcgagg aaggaagctt gctgccttat
    42061 cttcatgaac aaggagaacc tccatggcat tacaaacaga aggacgactg gttttagcat
    42121 tgttgatgat agacagcgcc ttgtcttcgt ctgcatcctt atccacatag acatggacaa
    42181 tcccagtccc tgtctcgata acaggtacaa tcgcattctc aaccactgca ttgatcaagc
    42241 cagctcctcc acgaggaatg agaagatcta gataaccctt ggccttcatc atggcatagc
    42301 tactttcacg gctagtatct tccaccagtt gaatcacatt tggatgaata gtagtcgtct
    42361 ccaagccctt cttcaagact gtgacaatgg catgggttgt ttgataggca tccttaccac
    42421 tacgaagaac aaccgcattt ccactcttaa gagtcaaagc agccgcatca gacgtcacat
    42481 ttggacggct ttcatagata ataccgatga cacccatagc tacacgtttt tttgtgataa
    42541 ccaaaccatt ttcaagctga cttgtttcta aaacttcacc gattggatct ggtaaggcaa
    42601 ccacttcacg aattcctctt gccatcgctt ctatacgatc tgcatccaaa taaagacgat
    42661 ccaacatcac atctgagatt ttccccttag ccgctgccat atcgagggca ttagccgcta
    42721 aaatttcctc agtagcagcc actaagtgat cagccatggc tagcaaggct tggtttttca
    42781 cttcttcact agctgtgtta atcgattttt taacagcctg tacctgttca aattgttctt
    42841 gtctactcac catagtttac ctctaaaatt ctgtaaaaag tagttggatt tcaggagtaa
    42901 tggaaatcca gtcgtcacgg taaatcaaga cacccttggc tttttgagaa cgcaacatat
    42961 cctccaaagc agatgctcca aattgcacgc gtccttttcc aagtgatttt ccactttcct
    43021 tgtcaaatac tgtcacgata tcaccgtaag aaaaggctcc ttctgcttca acgataccag
    43081 ataagagaag actctttcca tgttgagaga gagcttccgc agccccttta tcaacccaaa
    43141 tagaaccttg actctgagca tagaaggcaa gccattgttt ctgggtacga agccccttct
    43201 cttgagcaac aaagtaagaa ccatcctcgg tctcctctgc cgcctcaatc atggaatctg
    43261 atttcaagga tgagcagata taaacaggaa ctcctgattc cgtcgcgata gttgcagcct
    43321 taatttttgt tagcatgccc ccagttccgt ttgacgaacc agctccacca gccatatcaa
    43381 taatctcacg attgatggtc tcgattcgct ccaagcgttt ggctcttggg tctgaattag
    43441 gatttccagt atagagaccg tctacatctg tcaagaggac caaaaggtca gcttggacca
    43501 tggccgctac ctgggcactc agagtatcat tgtccccaac cttgagctca tcaataacga
    43561 cactatcgtt ctcgttgata ataggaattg ccccacggct aagtagaact gacaaagcct
    43621 gatgggcatt tttataacgg cgcttatcca caaaatcatc ctgggtcagc aagatttgtg
    43681 cagaaacgat ttggcgcaag agaagattag tcgtgtattc ttccaacaaa agcccttgtc
    43741 ctaccgctgc tgaagcctgt ttatcagtaa tcttagtcgg acgcttttta aatcctaaga
    43801 ccccaaaacc agctgcaatg gcacctgacg acaccaaaat caattcatga ccagactcgt
    43861 gcaacatagc caactgctgg gtgatagcct ttaccttact acgtgataaa cttccatcct
    43921 catttgtcag agaagaagtc ccaaccttaa agacaatccg tctgtatttt atagtctcac
    43981 tccgtttctt catatttatc cattataaca tgaataacag gaaatagaaa agagttgata
    44041 ggaaaaagag gctctataat atttgtagtg ggtaaatccc ctatggatat tatggagcct
    44101 attttt
//
LOCUS       DAVFJR010000012        43960 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVFJR010000012 DAVFJR010000000
VERSION     DAVFJR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.012"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            137..2548
                     /locus_tag="VU722_000884"
     CDS             137..2548
                     /locus_tag="VU722_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU1771891.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLVKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            2798..3499
                     /locus_tag="VU722_000885"
     CDS             2798..3499
                     /locus_tag="VU722_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771892.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            3501..6209
                     /locus_tag="VU722_000886"
     CDS             3501..6209
                     /locus_tag="VU722_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU1771893.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQDQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(6305..6796)
                     /gene="tpx"
                     /locus_tag="VU722_000887"
     CDS             complement(6305..6796)
                     /gene="tpx"
                     /locus_tag="VU722_000887"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU1771894.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(6919..7848)
                     /gene="psaA"
                     /locus_tag="VU722_000888"
     CDS             complement(6919..7848)
                     /gene="psaA"
                     /locus_tag="VU722_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU1771895.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(7880..8728)
                     /locus_tag="VU722_000889"
     CDS             complement(7880..8728)
                     /locus_tag="VU722_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU1771896.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(8725..9447)
                     /locus_tag="VU722_000890"
     CDS             complement(8725..9447)
                     /locus_tag="VU722_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU1771897.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            9738..11630
                     /gene="pepO"
                     /locus_tag="VU722_000891"
     CDS             9738..11630
                     /gene="pepO"
                     /locus_tag="VU722_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU1771898.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(11753..12382)
                     /locus_tag="VU722_000892"
     CDS             complement(11753..12382)
                     /locus_tag="VU722_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU1771899.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            13376..15598
                     /locus_tag="VU722_000893"
     CDS             13376..15598
                     /locus_tag="VU722_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU1771900.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            15628..16071
                     /locus_tag="VU722_000894"
     CDS             15628..16071
                     /locus_tag="VU722_000894"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU1771901.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(16338..16523)
                     /locus_tag="VU722_000895"
     CDS             complement(16338..16523)
                     /locus_tag="VU722_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771902.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(16542..16955)
                     /locus_tag="VU722_000896"
     CDS             complement(16542..16955)
                     /locus_tag="VU722_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771903.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(17086..17732)
                     /locus_tag="VU722_000897"
                     /pseudo
     CDS             complement(17086..17732)
                     /locus_tag="VU722_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(17909..18559)
                     /locus_tag="VU722_000898"
     CDS             complement(17909..18559)
                     /locus_tag="VU722_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU1771904.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            18671..19513
                     /locus_tag="VU722_000899"
     CDS             18671..19513
                     /locus_tag="VU722_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU1771905.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            19589..20026
                     /locus_tag="VU722_000900"
     CDS             19589..20026
                     /locus_tag="VU722_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU1771906.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            20095..20397
                     /locus_tag="VU722_000901"
     CDS             20095..20397
                     /locus_tag="VU722_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771907.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYSGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(20488..21561)
                     /locus_tag="VU722_000902"
     CDS             complement(20488..21561)
                     /locus_tag="VU722_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU1771908.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFNWKIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            21717..22394
                     /locus_tag="VU722_000903"
     CDS             21717..22394
                     /locus_tag="VU722_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1771909.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            22387..23361
                     /locus_tag="VU722_000904"
     CDS             22387..23361
                     /locus_tag="VU722_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU1771910.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(23410..25353)
                     /gene="thrS"
                     /locus_tag="VU722_000905"
     CDS             complement(23410..25353)
                     /gene="thrS"
                     /locus_tag="VU722_000905"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU1771911.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(25411..25587)
                     /locus_tag="VU722_000906"
     CDS             complement(25411..25587)
                     /locus_tag="VU722_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU1771912.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(25594..25734)
                     /locus_tag="VU722_000907"
     CDS             complement(25594..25734)
                     /locus_tag="VU722_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU1771913.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(25991..26365)
                     /locus_tag="VU722_000908"
     CDS             complement(25991..26365)
                     /locus_tag="VU722_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771914.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIISLLYSYRFRFSLWWLVGNGLLFYFTIITFGEFILIYLLIYETVALVSM
                     DSGISIKHILQKMKNKKLSQNP"
     gene            26604..27233
                     /locus_tag="VU722_000909"
     CDS             26604..27233
                     /locus_tag="VU722_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU1771915.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            27374..27643
                     /gene="rpsO"
                     /locus_tag="VU722_000910"
     CDS             27374..27643
                     /gene="rpsO"
                     /locus_tag="VU722_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU1771916.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            28457..29071
                     /locus_tag="VU722_000911"
     CDS             28457..29071
                     /locus_tag="VU722_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU1771917.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(29364..30113)
                     /locus_tag="VU722_000912"
     CDS             complement(29364..30113)
                     /locus_tag="VU722_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU1771918.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            30246..32582
                     /locus_tag="VU722_000913"
     CDS             30246..32582
                     /locus_tag="VU722_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU1771919.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            32684..33361
                     /locus_tag="VU722_000914"
     CDS             32684..33361
                     /locus_tag="VU722_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU1771920.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            33348..34145
                     /locus_tag="VU722_000915"
     CDS             33348..34145
                     /locus_tag="VU722_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU1771921.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            34162..35265
                     /locus_tag="VU722_000916"
     CDS             34162..35265
                     /locus_tag="VU722_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU1771922.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            35521..36540
                     /gene="galE"
                     /locus_tag="VU722_000917"
     CDS             35521..36540
                     /gene="galE"
                     /locus_tag="VU722_000917"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU1771923.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            36542..37507
                     /locus_tag="VU722_000918"
     CDS             36542..37507
                     /locus_tag="VU722_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1771924.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRHFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRILILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(37558..37764)
                     /locus_tag="VU722_000919"
     CDS             complement(37558..37764)
                     /locus_tag="VU722_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU1771925.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDGPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            37816..38292
                     /locus_tag="VU722_000920"
     CDS             37816..38292
                     /locus_tag="VU722_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU1771926.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            38301..38972
                     /locus_tag="VU722_000921"
     CDS             38301..38972
                     /locus_tag="VU722_000921"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU1771927.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            39103..39441
                     /locus_tag="VU722_000922"
     CDS             39103..39441
                     /locus_tag="VU722_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU1771928.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            39444..40073
                     /locus_tag="VU722_000923"
     CDS             39444..40073
                     /locus_tag="VU722_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU1771929.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            40313..41464
                     /locus_tag="VU722_000924"
     CDS             40313..41464
                     /locus_tag="VU722_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1771930.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            41777..42526
                     /gene="truA"
                     /locus_tag="VU722_000925"
     CDS             41777..42526
                     /gene="truA"
                     /locus_tag="VU722_000925"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU1771931.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            42516..43289
                     /locus_tag="VU722_000926"
     CDS             42516..43289
                     /locus_tag="VU722_000926"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU1771932.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNVGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            43267..43728
                     /locus_tag="VU722_000927"
     CDS             43267..43728
                     /locus_tag="VU722_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1771933.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        12674 a         8294 c        10077 g        12915 t
ORIGIN      
        1 ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt tttttctaca
       61 caaaataggc tccataatat ccataggggg ttacccacta caaatattat agagcctttt
      121 atgttagtat ggaagtatga taaggaataa aaaacaagat tatgtactgg cctacaaaca
      181 accagcttca accacttaca tgggttggga agaagaagct ttaccgatag gcaatggttc
      241 tttaggagca aaagtatttg gccttatagg ggctgaacgg attcaattta atgaaaaaag
      301 tctctggtct ggaggtccac ttcctgatag ttcagattat cagggtggaa atcttcagga
      361 tcagtatgtt tttttagctg agattcggca ggctttggag aagagagatt acaatctggt
      421 taaggaactg gctgagcagc acctaattgg gccaaaaacg agtcaatatg ggacctatct
      481 gtcttttggg gatattcaca ttgagttcag ccagcaaggt acgactttgt ctcaggtgac
      541 ggactatcag agacagctga atattagtaa ggcacttgcg acgacttctt atgtctataa
      601 gggaacgcga tttgaacgta aagcttttgc gagttttcca gatgatctct tggttcaatg
      661 ttttactaag gaagggttgg aaactctaga ttttactata gaactatcct tgacctgtga
      721 tttggcttct gatggaaagt atgaacagga aaaatctgat tacaaggagt gtaagttgga
      781 tattactgat tctcatatct tgatgaaggg aagagttaag gataatgatc tgcggtttgc
      841 tagttatcta gcttgggaaa cggatggaga tattagagtt tggtcagata gggttcagat
      901 atcaggagcc agttatgcca atctcttctt ggccgctaag acggattttg cccaaaatcc
      961 tgctagcaat tatcgcaaga aactagattt agagcaacag gtgatagact tggtggacac
     1021 agctaaagaa aagggctata cccaattgaa atcaaggcat atcgaggact accaagcctt
     1081 attccagcgt gttcaattgg atttggaagc tgatgttgac gcatccacta cagatgattt
     1141 gttaaaaaat tataagccac aagaagggca ggctttggag gagctgttct tccagtatgg
     1201 acggtattta ttgattagtt cgtccagaga ctgcccagat gctctaccag ctaacctaca
     1261 gggagtctgg aatgcggtcg acaatcctcc ttggaattcg gactatcact taaatgtcaa
     1321 tctgcagatg aattattggc cagcctatgt taccaatctc ctagagacgg tctttccagt
     1381 catcaactat gtagatgatt tgcgtgtcta tggtcgtcta gcggctgtaa agtatgcagg
     1441 aatcgtctct cagaaaggtg aggagaatgg ttggttggtt catactcaag cgactccctt
     1501 tggttggacg gcacctggtt gggattacta ttggggttgg tcaccagctg ccaatgcgtg
     1561 gatgatgcaa accgtttatg aagcctattc attttatagg gaccaagact atctcagaga
     1621 gaaaatttat cccatgttga gggaaacggt tcgtttttgg aatgcctttt tacataagga
     1681 tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc ccagaacatg ggccgatttc
     1741 gattggcaat acttatgacc aatctctgat ttggcagtta tttcatgatt ttattcaggc
     1801 tgctcaggaa ttgggactgg atgaggactt gttgactgag gttaaggaga agtctgattt
     1861 actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg gagtggtatg aggaggaaga
     1921 gcagtatttt caaaatgaga aagtggaggc ccagcaccgg cacgcttccc atctagtggg
     1981 actctatcct ggcaatctct ttagctacaa gggacaagag tatattgaag cggcacgtgc
     2041 tagcctcaat gatcgtggag atggcggcac aggctggtcc aaggctaata agatcaatct
     2101 ctgggcgcgt ttgggagatg gcaatcgagc tcataaatta ttggcagagc agttaaaaat
     2161 atccaccttg ccaaatcttt ggtgtagcca tcctcctttt cagatagatg gtaattttgg
     2221 tgctactagt ggcatggcag aaatgttact ccagtctcat gcagcttatc tggtacctct
     2281 agctgcccta cctgatgctt ggtcaacagg ttctgtttca ggcttaatgg cacgtggaca
     2341 ttttgaagtg agcatgagct gggaagataa aaaactctta cagttgacca ttttatcaag
     2401 gagtggagga gatttgcgag tttcttatcc agatattgag aagagtgtga ttaaaatgaa
     2461 tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt atttcggtgg caacagcaga
     2521 aggtgatctt gttcaatttt atttttaaga agatgttata aggcagtaat ttgaaacttc
     2581 cttttaataa ggatttaaga atataggcag tttccaacta gttgaaaaag cgttataatg
     2641 ataataggaa gtaatactca atgaaaatca aagagcacaa actaggaagc tagccgcagg
     2701 ttgctcaaaa cagtgttttg aggttgtaga tggaagctga cgtggtttga agagagattt
     2761 tcgaggagta taatttgttt gatagagggt ggatctgatg gcttatattg agatgaaaca
     2821 ctgttacaag cgttatcagg ttggggacac ggagattgtg gccaatcgtg atgtgaattt
     2881 tgagattgaa aagggggagc tggttattat ccttggtgct tcaggtgcag gcaagtcaac
     2941 agttcttaac cttcttgggg gaatggatac caatgatgaa ggggaaatct ggattgatgg
     3001 tgttaatatt gcggattata gttcccacca gcgcaccaat taccgtagaa atgatgtggg
     3061 gtttgttttt cagttttata atctagtttc taatctgaca gctaaggaaa atgtggaact
     3121 ggcttctgaa attgtgacag atgccttgaa tcctgatcag gtcttgacag atgtaggtct
     3181 ggctcatcgt ctcaataact ttccagccca gctttctgga ggggagcaac agcgagtctc
     3241 cattgcacgc gcggtagcca aaaatcctaa aattctcctt tgtgatgaac cgactggagc
     3301 cttggattat cagacgggca agcaggtttt gaaaattctc caagacatgt ctcgtcaaaa
     3361 gggagcgacg gtgatcatcg tgactcataa tggagctttg gcgcccattg ctgatcgcgt
     3421 gattcaaatg cacgatgcca gtgtcaagga tgtggtgctc aaccagcatc ctcaggatat
     3481 tgacagtttg gagtactagc atgatcaagc gaaaaactta ttggaaggac ttaattcagt
     3541 ccttcacagg ctccaagggg cgttttttat ccatcttgat cctgatgatg ttgggatctc
     3601 tagccttagt aggcctcaaa gtaaccagtc ccaacatgga ggcgacagct aatgcttatt
     3661 taacaactgc tcaaacctta gatttggcag tcatgtctaa ctatggcttg gatcaagcag
     3721 accaagaaga actaaaacag acggagggcg cagaggtcga gtttggctat ttgacagatg
     3781 tgactatgga taatgggcag gatgccattc ggctgtactc caaaccagag cgaatttcaa
     3841 cctttcagct aagaaaggga cgacttcctc agtcagacaa ggaaatcgct ttgaccactc
     3901 atttgcaaga ccaatacagc gtgggacagg agattagttt taaagaaaaa gaagagggtc
     3961 attcctcttt aaaagaccat acttatacca ttactggttt tgtggattcg gctgaaatcc
     4021 tctcccagcg agatatgggc tacgcaggaa gtggaagtgg gactctgaca gcctatgggg
     4081 tgattttacc tagtcaattt gatcagaaag tctacaatat agctcgtttg aaatatcaag
     4141 atttagcagg tttaaatgcc ttttcatcag cttatgaaga aaaatccaag caacatcagg
     4201 aagagcttga acaaatttta tcagataatg gcaaggtacg tctgcgactt ttgaaaaaag
     4261 aaggacaaga gtctctagac aaggggcaag agacccttga caaggctcag actaatttgc
     4321 aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat acaggctcaa gaaagtcaac
     4381 tagccttgtt tcctcaagct cagagagaac aggctagtgc tcaacttacc caagccaagc
     4441 aggaattggg caaggaagag gacaaactaa agcaagctga acaaaatcta gcccaagaaa
     4501 aggaaaaatt agaaaaacat cagcaagtct tggatgattt ggcggagcca aggtatcagg
     4561 tttataatcg tcagaccatg ccaggtggtc agggctatct tatgtatagc aatgcttcat
     4621 ccagtattcg agcagtgggc aatatctttc ctgtggtact ttatgccgta gcagccatgg
     4681 tgacctttac gaccatgact cgctttgtag acgaagagcg aactcatgca gggattttta
     4741 aggccttggg ttaccgtagt aaggatatta tcgccaagtt tctcctttat ggactagtag
     4801 ctgggactgt cggaacggct ctaggtagta tacttggtca ttatttgcta gccagtgtaa
     4861 tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac ccagattcag ttctattgga
     4921 cctatagctt actagctctt gtcttgagct ggttggcgag tgtgttacca gcctatctgg
     4981 tggcttggag ggaacttcat gccgaagcag cccagcttct acttcctaaa cctcctgtca
     5041 aaggagctaa aatcttattg gagcgtatcg gttttatctg gcgtcgtctc agttttactc
     5101 ataaggtaac agcccgcaac atctttcgtt ataagcagag aatgttgatg acaatctttg
     5161 gtgtggcagg ttctgtagct ctgctctttg caggtttggg aatccaatct tctgtagcag
     5221 gagttccgtc taaacagttt caacaaatcc aacagtatca gatgcttgtc tctgaaaatc
     5281 ctagtgcgac caatcaggac aaggtagagc tagcagaagt gttgaaaggg caggagatac
     5341 tagcctacca gaaaatctat tctaaaacgc tagacaagga tttcaaaggc aaggctggtc
     5401 ttcaaaacat tactcttatg atgatagaga aggaagattt gactcccttt atccatcttc
     5461 aacatcatca gcaggagctg acattaaaag atggcatcgt tattacagct aaactcgccc
     5521 agctggcagg tgtcaaggtt gggcagactt tagaaattga aggtaaggaa ctaaaggtcg
     5581 ctgctattac tgagaactac gttggtcact ttatttatat gagtcaggct agctatgagc
     5641 aactttacgg acagctaccc caagccaaca cttatctggt ctcattaagg gataccagtg
     5701 caactagtat cgaaagtcag gcgggcttgc ttatgaatca atctgcggtg tccagcgttg
     5761 tccaaaatgc ttcagccatt cgactcttcg actctatcgc tagctcactc aatcagacca
     5821 tgaccatctt ggtcatcgta tcggttctat tagctattgt catcctttac aatctgacca
     5881 atatcaacgt agctgagaga atccgtgaac tctccactat caaggttctc ggttttcata
     5941 ataatgaagt caccctctac atttaccgtg agacgattgt gctgtccctt gtgggaatcg
     6001 tacttggtct ggtagctggt ttctatttac accaattttt gattcaaatg atttcgcctg
     6061 cgactattct cttttatccg caggtaggct gggaagtcta tgtaatccca gtggcaacag
     6121 taagcatcat tttgaccttg cttggtttct tcgtcaatta ttatctgaga aaggttgata
     6181 tgttagaagc cctgaaatct gtagagtaag gtagttattt ttagctgatt gaacttctat
     6241 ttactaatat tcaaaaatcc tctgtcacaa agagcaggga gctctttgtg acagaggatt
     6301 ttttctatag ggctttagca gctgcaattg cggcttcgaa gtttggctca gaattgatat
     6361 tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc gaggacaaag actgcgcgtg
     6421 ctaataggtg ccattcgttg atcaagaggg cataatcgcg cccgaaagaa tggtcaaagt
     6481 agtctgaaag cataatggca ttgtcaaggc cttcagcacc gcaccaacgt ttttgagcaa
     6541 aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc cagtccagcc aattcttcat
     6601 taaaacgacg tgtttgagtt gagcagatac ctgtatcgat agaaggaacg acactcaaga
     6661 cttttttctt gccatcaaaa tcagccagag attttttaga aagatctgtt gtagtaagag
     6721 aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc tgtaaagctc acaggatttc
     6781 cgagaaaagt taccatagga tactccaatc ttttttcttc cattgtatct aaaacagtca
     6841 gaattttcca atgatttgac cggaaatgtg tgcatagaaa aaacgccagc tcacatgaga
     6901 atgacgtttt tcagaggctt attttgccaa tccttcagca atcttgtcaa ggttgtattt
     6961 catcatgctg tagtagctgt cgccttcttt accttgttct gcgatagagt cagtaaagat
     7021 ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt ttcattggac ggtcatccac
     7081 acttgattct acaaagagtg atggaacttt tgtttggcga agtttttcaa ccaaggtctt
     7141 gatttgttca ggagttcctt cttcttcagt attgatttcc cagatgtagg cacttgggac
     7201 accataggct ttagagaagt atttgaatgc tccttcgctg gttacaatga gtttcttttc
     7261 agcagggatc ttattaaatt tatccttact ttctttatca agtttgtcta acttatcagt
     7321 atattctttg agattttttt catagaattc tttattgtta gggtctttgg cgctcaattg
     7381 tttggcgata tttttagcaa aaataatacc gttttcaagg ttaagccaag cgtgtgggtc
     7441 ttcttttcct ttttcatttt gaccttcaag gtagataaca tcaacgccgt cgctgactgc
     7501 gaagtagtct ttgttttcag ttttcttggc attttctacc aattttgtaa accaagcatt
     7561 gccacctgtt tcaaggttga taccgttata gaaaatcaaa tcagcctcag aagttttctt
     7621 aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc ccaatcggaa cgatactatg
     7681 aaggtcaatt ttgtcaccag caatattttt agtaatatca gcgatgattg agtttgtagc
     7741 aacaactttt agtttttgac cagaagttgt atcttttttt ccgctagcac atgctacaag
     7801 aatgattgca gaaagaaaga gaacgagtaa tgtacctaat tttttcatta gatcctccaa
     7861 tttattaggg ctttgcccct tattttaaca aatgtttatt tttcagtttc aaatatcgtt
     7921 gtttgggagc gataaagaag ctaatgagaa agaaactagc agctgtaagc acgatactag
     7981 aacctgccgc aacattaaaa ctatagccaa taaagagtcc caaaactgaa gcagtagctc
     8041 cgaaggttga ggaaaggaaa atcatacttt tcagactatt agcatacaga taagcagttg
     8101 cagctggggt aatcagcatg gctacaatca ggatagttcc gacactttgc atggctgtca
     8161 cagacacgag agtcaggagt accatgagaa ggtagtgata gaaattgaca ggcattccca
     8221 tggctttagc caagagttca tcaaaggaag ttatcaagag ttgcttgaag aaaatccaga
     8281 ttaacaagag gatggctgcc cccacaccca tagtaataaa catatccgta tcttggacgg
     8341 ccaggatatt accaaaaagg atatggaaaa ggtcagttga acttttagcg acaccaatca
     8401 agatgatacc gagggctaag aaagaagaaa aggtaatgcc gatggcggta tcgcttttga
     8461 taatcgagtt tcctttgatg taggtaatga tgatggcagc tagcaatcca aagacaatgg
     8521 ctccgataaa gaagtcaagg cccaagatga aggagagggc tacacctggt aagacagcat
     8581 gtgaaatggc atctcccatg agtgacatcc cgcgtagaat aatgaaacat cccacggctc
     8641 cagctacaat cccgacgaca atagctgtta tcaaggcatt ttgtaggaaa tggaattttt
     8701 gcaatccatc gataaattct gcaatcatag gtcacctcca ttgaaaaaga gttgattacc
     8761 gtaagcttct tttagattgg tttcggtaaa agtttctttt gttggaccaa aggcaatcac
     8821 ttctcgattg acaagtaaga cttgatcgaa gtagtgggga atcttgctga ggtcgtggtg
     8881 aacgatgaga accgtcttcc cagctttttt caaatctctc agcgtattca tgatgatttc
     8941 ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag aggatatagt cggcttcctg
     9001 caccaaacat ctggcaatca agacccgctg gaattgacct ccagacagtt gactaatttg
     9061 acgttcagcg tagtcagcta ggccgacgat ttcaagggcc tcttgcactt tcttccaatg
     9121 tttagccttt aaacttcgaa agagaggaat agagggaaat agtcctaacg agacgcattc
     9181 cttgaccttg atgggaaagt tgtagtcgat attgattttt tgttcgacat aggcaattcg
     9241 gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc tgaccttgat gtgggataat
     9301 tcccagcata ccttttaata gtgttgattt cccagcgccg tttggaccaa tgatgccggt
     9361 aattgttggt ccatggagca ctagtgaaat atccttaagt gccaacgttt ctttgtagga
     9421 gacactgagg ttttcgatac gtatcataaa cttgtattcc tcctgtctct taatatacat
     9481 taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta aaataataac tgaaaaatag
     9541 attctaaaga taactttcag gataaatttc taaattataa aacgcatagt atcaagtgta
     9601 aaaaacttgg aattatgcgt tttatcatgg aaagattttt tataatagct aaaaaataat
     9661 agttaaatgg ttattaattg cattccctag tgatttttgt taagataaat gcaaatacaa
     9721 atgaaagcga gaacaagatg acacgttatc aagatgattt ttatgatgct atcaatggag
     9781 aatggcaaca gacagctgaa atcccagcag ataagtctca aacaggaggt tttgttgatt
     9841 tagaccagga aattgaagac ctgatgctgg cgacaacaga caagtggtta gcaggtgaag
     9901 aagtgcctga ggatgctatc ttggaaaact ttgtcaaata ccaccgccta gttcgtgatt
     9961 ttgacaagag agaagctgac ggtatcacac ctgtcttacc actccttaaa gaattccaag
    10021 aattggagac ttttgcggat tttacagcta aactagcaga gtttgagctt gcaggaaaac
    10081 caaacttcct tccttttggt gtatcgccag actttatgga tgctagaatc aatgttctat
    10141 gggctagcgc tccaagcaca atcttgccag atacgaccta ctatgcagaa gaacatcctc
    10201 agcgcgaaga gctcttgact ctttggaaag aaagcagcgc aaatctcctc aaggcttatg
    10261 atttctctga tgaagaaatt gaagacttgc tagaaaaaag acttgaattg gaccgccgag
    10321 ttgcggcagt ggtgctctct aatgaagaaa gttcagaata tgctaaactc tatcatccat
    10381 attcttacga agatttcaag aaattcgcgc ctgccctacc tttggatgac ttcttcaaag
    10441 cagttattgg gcaattacca gacaaggtta ttgtagacga ggaacgtttc tggcaagcag
    10501 cagagcaatt ctacagtgag gaagcctggt ctctccttaa agcaaccttg attttgagtg
    10561 ttgtcaatct ttcaaccagc tatttaacag aggatatccg tgttttgtct ggtgcctaca
    10621 gccgtgccct ttctggagtt ccagaggcaa aagataaggt caaagcagct tatcatctag
    10681 cacaagaacc tttcaagcaa gccctgggtc tttggtacgc ccgtgagaag ttctctccag
    10741 aagccaaggc ggatgtggag aaaaaagtgg caaccatgat tgatgtttat aaggagcgtc
    10801 tgcttaagaa tgactggctc actccagaaa cctgtaaaca ggctatcgtg aagctcaatg
    10861 tgatcaaacc ttatattggc tatccagaag aattgcctgc acgttacaag gataaggtag
    10921 tgaatgaaac tgccagtctt tttgagaatg ctctagcctt tgcgcgtgtg gaaatcaagc
    10981 acagttggag taagtggaac cagcctgtag actataagga atggggcatg cctgctcata
    11041 tggtcaatgc ctactacaat cctcagaaga acctgattgt ctttccagca gccattttac
    11101 aggcgccttt ctatgacttg catcagtcat cttctgctaa ctacggtggt attggggcag
    11161 tgattgccca tgaaatttcc cacgcctttg atactaacgg ggcttccttt gacgaaaatg
    11221 gtagcctcaa ggattggtgg acagagagcg actatgctgc cttcaaggag aaaacacaaa
    11281 aagtcattga ccaatttgat ggacaggatt cttatggagc aaccattaac ggtaaattga
    11341 ctgtatcaga aaacgtggct gacttgggag gaatcgcagc agcgcttgaa gcagctaaga
    11401 gagaagcaga cttctcagca gaagagttct tctacaactt cggtcgcatc tggcgcatga
    11461 aaggtcgacc agaatttatg aaacttttgg ctagcgtcga tgtgcacgca ccagccaaac
    11521 tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt tacaacctat gatgtcaaag
    11581 aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat tatttggtaa tacaaaaaat
    11641 ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac cttgatagga tgccttttgt
    11701 aatagaaaga tttgctggat agtttactta aatttcgatt gtcatcatct tgctagaaaa
    11761 agggattgaa ggccttttcg tgagcgatag tagtagctgg accatgtcct ggatagacat
    11821 cgtagtttgg tagggtgaag agttgggtct ggatactatg aaggagttgc tccatgctac
    11881 cagtcggaag gtcggtccgt ccgatagttt cgcggaatag agcatctccc gtcaagacta
    11941 ggtgagcatc aggaaagact agggaaacac caccgataga gtgccctggg gtcggtagaa
    12001 ccttaaaacg aaattcctct agttggtatt cttcgtgaaa gacaaaggtg tgttctgcag
    12061 gttttgtgac cacatctgcc atatcatcgt ggcgagggag accggagaga ttatcgacag
    12121 gagtgtagag ccagctggct tcgctctctg cgatatagac aggaggattg ccaaacgtct
    12181 cgcgaaccaa gtccagactc atgatatggt cataatgggc gtgggtcaag agaatagcac
    12241 agatcggttt gttgatcttc tcgattgtct gacgaatggc ttcccaatga ctaccaggat
    12301 cgacgacgat gaggtgcttt tcgccttcta gataataggt attttcatag gcaacaggat
    12361 tcacggtttt atggattttc atactagctc caatctcaaa gaatgtacta atactcttcg
    12421 aaaatctctt caaaccgcgt caactttatc tgcaacctca aagcagtgct ttgaacagcc
    12481 tgcggctagc tttctagttt gctctttgat tttcattgag tataaattaa gtatagcaca
    12541 gttagggaga ataggtaagg atttaaaatg aacttaaaaa ccagcatgac tagatgaaga
    12601 caggctggtt atcaatttat caatattgga aaggtgtcaa ttgcccttca taggttgcat
    12661 aaactccgtc attagcttgt ttgatagacg tgatgtttag agtgctaccg tagttggctt
    12721 ctcatttgtc gctatattca ctataagtta tcctactggg caggttctgg tcgttagcat
    12781 agtattgaac gagtttttta tagctttgct ggctgaatag gaacaggcag caaactccta
    12841 acattaggag agcaaagata gaaatagcag tttttttcat aggtattctc cttataaact
    12901 aaaggataga agaaagtatc ttgaggattt ttatactctt caaaaatctc ttcaaaccgc
    12961 gtcaacgtcg ccttgccgta tatatgtgac tgactttgtc agtcttatct acaacctcaa
    13021 agcagtgctt tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt
    13081 attaattcca aaatccagtc aaggtaccag tgtatgtgat acgagttcca ccgtttatct
    13141 ttcgtatctt caatggaatt ggggaaatca gaaagtcttt gggttacaat atggtttccg
    13201 ttcttctatc tctccttcta tcacctaagt ttaaaatcta acttcgtagt atattatggg
    13261 tcaataattc agaattatca agcaattttg aattattttt ttcttattct gttccaatct
    13321 agttttcata ttcttaaaaa agtgataaaa tggtaggaag aattggagag tagagatgcc
    13381 gaaagaagtg aatttaacag gcgaagaagt tgtcgcttta accaaagaat atttaacgga
    13441 agaggatgtt cattttgtcc ataaggcctt ggtctatgct gttgaatgcc acagtggtca
    13501 atatcgcaaa tcaggcgagc cttatatcat tcaccctatc caagtggcag gtattttagc
    13561 taagctaaag ctggatgctg taacagtagc ttgtggattc ttgcatgatg tggtggaaga
    13621 tacagatgcg accttggacg atttggaaag agagtttggt cctgatgtgc gggtgattgt
    13681 tgacggagtt accaagcttg gcaaggtcga gtacaaatcg atcgaggagc aattagcgga
    13741 aaatcatcgc aagatgctca tggccatgtc tgaggatatc cgcgttattt tggtcaaact
    13801 gtctgaccgc ttgcacaata tgcggaccct gaaacatctt cgaaaagaca agcaggagcg
    13861 tatttccaaa gaaaccatgg aaatctatgc cccacttgcc catcgtttgg ggatttccag
    13921 tgtcaaatgg gaattagaag acttgtcttt ccgttatctc aatccaacgg agttttacaa
    13981 gattacccat atgatgaagg aaaagcgcag ggagcgtgag gccttggtgg atgaggtagt
    14041 cacaaaatta gaggagtata cgacagaacg tcacttgaaa gggaagattt atggtcgtcc
    14101 caagcatatt tactcaattt tccgcaaaat gcaggacaag agaaaacggt ttgaggaaat
    14161 ctatgatctg attgctattc gttgtatttt agatacccaa agtgatgttt atgccatgct
    14221 tggttacgtg catgaatttt ggaaaccgat gccaggtcgc ttcaaagact atattgccaa
    14281 ccgcaaggcc aatggttatc agtctatcca tacgactgtt tatggaccaa aagggccgat
    14341 tgaattccag attcgaacca aggaaatgca cgaggtggct gagtatgggg ttgcggctca
    14401 ctgggcttat aagaaaggta taaaggggca agttaacagc aaggaatcag ctattggaat
    14461 gaactggatc aaggagatga tggagctcca agaccaggct gatgatgcta aggaatttgt
    14521 ggactctgtt aaggaaaact atctggctga ggagatttac gtttttaccc cagatggagc
    14581 tgtccgttcc cttcccaaag attcaggacc gattgatttt gcctacgaaa tccataccaa
    14641 ggtcggtgaa aaagcaactg gtgccaaggt caatggccgc atggttccac tgacaaccaa
    14701 gttaaagaca ggggatcagg ttgaaattat cgccaacccg aactcctttg gacctagccg
    14761 tgactggctc aatatggtca agactagcaa ggcgcgcaat aagattcgcc agttctttaa
    14821 aaaccaagat aaggaattgt ctgtcaacaa gggtcgtgag atgctgatgg ctcagttcca
    14881 agaaaatggc tatgtggcaa ataaatttat ggacaagcgc cacatggatc aagttctgca
    14941 aaagaccagt tacaagacag aagactccct ctttgcggcc attggttttg gggaaatcgg
    15001 tgcgattacc gtctttaacc gtctgactga aaaggaacgc cgtgaggaag agcgtgccaa
    15061 ggccaaagct gaggcagagg agcttgtcaa aggtggcgag gtcaaggttg aaaataaaga
    15121 aaccctcaag gtcaagcatg aggggggagt ggttattgaa ggtgcttctg gtctcctagt
    15181 gcggattgct aagtgttgta accccgtgcc tggtgacgat attgttggct acattaccaa
    15241 gggtcgtggt gtggctattc accgtgtgga ctgtatgaac ctgcgtgccc aagaaaacta
    15301 cgagcaacgt ctccttgatg tggaatggga agaccagtac tctagctcaa ataaggagta
    15361 tatggcccat atcgatatct acggtctcaa ccgtacagga ctgttgaacg atgtactgca
    15421 agttctttca aatacaacca agaatatttc aacggtcaat gcccaaccaa ccaaggatat
    15481 gaagtttgct aatatccatg tgtccttcgg tattgccaac ctctctacac tgaccacggt
    15541 tgtcgataaa attaagagtg tgccagaagt ttactctgtc aaacggacca acggctagtt
    15601 gtcctagctc ttactagaaa ggctattatg aaaatcatta tccaacgggt taaaaaagcc
    15661 caagtgagta tagaaggcca gattcaggga aaaatcaatc agggactttt attgctggtt
    15721 ggtgttggac cagaggacca agaggaagat ttggactatg ctgtgagaaa actggtcaat
    15781 atgcggattt tttcagacgc agaaggcaag atgaacctgt ctgtcaaaga tattgaagga
    15841 gaaatcctct ctatttctca gtttaccctc tttgcggata ctaagaaagg caatcgtcca
    15901 gcctttacag gggcagctaa acctgatatg gcatcagact tctatgatgc tttcaatcaa
    15961 aaattagcgc aagaagtgcc cgttcagaca ggcatctttg gagcagatat gcaggttgag
    16021 ctggttaata acggacctgt taccattatc ctagatacta aaaagagatg agaaagacca
    16081 agcccagtcg gcttggtctt tctcatctat cataaaatac tccaaaaaga aatcggttct
    16141 tgatatgctt gggggaagtc tcttttcagg ctttggcaga tgcgatagga agggatgaga
    16201 tgtcctagga tgaggagagt tccctgaagg aaaagtggaa tatcacttaa agacaccaag
    16261 gagagaatca tcaggctatc ccataggaga atttgtaaag caaaacgcca gaatctcggt
    16321 ctaatctggg aatagagtta actaaagtgg tcacaaagtt ggtttgaaag ataggtcaat
    16381 agcacaggat gaaagaaaat gagccaaccg ctataaatca aaatccagtc ccaagtaagc
    16441 tcccttttaa atgtcaaaaa tgccagcatg attccatcaa tgacaaggag ttgaatggtt
    16501 ttgatgaaga tgattttttt catgctaaaa cctccttttc cttagagaca ctcccataaa
    16561 gagatgtgtt tgtcgtaaaa gtctggatag ttttctccta ggtagtcagc tgtcatataa
    16621 taaaaagtag aatggcgagc agtgatgatt ggcataagag atgaaaaacg ctgagaacta
    16681 atgaaggcta agagaacaaa aaatagaaaa tcaatggtga gaatccctaa atagtagaag
    16741 cgaatctttt tattgatttg aggataaatc tcagcgaatt gatgtttgag tcggacgacc
    16801 aagagaaata gcaggagtcc ttgagcaagg aagaaaatta aaccagagag caagagccac
    16861 tcaaaagatg tctcgagtct agtgataaaa aatgcaaata gtagcaaatc aataactgca
    16921 attgctataa aatggattct atagagtttt ttcatgacaa gacctccctc ttttatctaa
    16981 cttcattcta ctctaaaaga atgggagtta caactaaaat gataaaaata gcagagggga
    17041 gattctctta agttgactag tattctttat ttgagtttcc ttctattatc taacttcttc
    17101 atcattccag acaaataaag ctccgattgc attgaggata taaaagatgt atttaccgat
    17161 attggcgaag tttccttgaa taccagcttt tgtcagctga acgaaattgt aaatcaacca
    17221 aaagccccac tgtccctcat tgcaaatgca ttcaaagcat tggcaatgag ggacagtgca
    17281 aaggcaatag ttgttacgta ggcaaggaga ttcatcttgc ccccatatcc gatatagttg
    17341 gtcacaaagg caaagaggaa ggcgatgatg gaaatgatga tggccgccaa ttttacctgt
    17401 ttttggctca tttggttggg tctgccttct tgcgaagctt tccatttctt tatagcaaag
    17461 gtataaatga ggaaggtgac gggataggta atgatggccg ccttatttcc aaggatataa
    17521 tcaatagcac cggacaaaat ggtattaaca ataccaaagt aatttcccca tttgcttaat
    17581 ttccccgtga aacgagtgga caacatggaa atcccaacgt tggttacgga aatcaatcca
    17641 aagggtacaa gagctgtcca tagtccccag tctacaaatt tatcgaggcg tgagttgaga
    17701 taaccagatg caatcgcaat cccaacgacc aaagcaaccc cgaagaggtc aaatcattta
    17761 gatgtagcaa aaatttttag tgattttttc ataggttaaa ctacctttct ttttttcaaa
    17821 tactctacca ccaaatgaaa gtaaaatcaa atgatagaaa taaaaccctg aaaataaaac
    17881 tttcagggtt ggtagggaac ttgagaaatt agttgatttt ctcgacatag agttgttttg
    17941 caatgtccat attcacttgt aaatcctcgt cgttactgag gatagtgaag gtattgctga
    18001 agccatcaaa ctgcttgact tggagctggt caccgatgtg aagtgagtgc ttgtccagat
    18061 aatggagaat gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca gcttccttga
    18121 tatcagctag tgggaggtta ttgatttcaa cgaggagttc tcccttggca ggaatagttc
    18181 ctccgtgggg gcaggtttta gggaaaccta gcagtttatc tagtctttcc acgaacaggt
    18241 cagagacagt gtgttccaag acctcagctt cctcgtgaat ctggtcactt gtatagtcta
    18301 aatgatgaac tagaaaaact tcaatcaagc ggtgcttacg atagagctca gagaccagtt
    18361 tgagaccgag gtcagtcagt agatagccac attccttgtc ctttaggatg agattttcac
    18421 ttttcattcg tttgatcatt tcagttacgg cagggggaga gacttgcatg cgagccgcaa
    18481 tttccttgtt ggtaatctta tgcaggtcta tgccaatttc ataaatacat tttagataat
    18541 cttctttgtt tggggtcatt cgtttcctct tgtctaatat ctttatctag tatatcaaaa
    18601 aaagctagat ttctctagct gtgacttttt atgttatact tattgcaaga gaaaaaacga
    18661 ggagatggat atgacgaaaa tagctcttct ttcagatatt catggaaata ccaccgcctt
    18721 ggaggctgtt ttggcagatg ctcagcagct aggagtggat gaatactggc ttttgggaga
    18781 tattctcatg ccagggacag gacgtagaag gattttggac ttgttggatc aactaccgat
    18841 tacggctaga gttttgggaa actgggaaga cagtctttgg catggtgtcc gtaaggaatt
    18901 ggacagtact cgccccagtc aacgctatct cttgcgccag tgccagtatg ttttagagga
    18961 aatttcccta gaagaaattg aagtgctcca caatcaacct cttcaaattc atcgtcagtt
    19021 tggggatttg acggtgggaa ttagccatca tctgcctgat aagaactggg ggcgagagtt
    19081 gattcatact ggcaaacaag aggagtttga ccgcttggtg actcatcctc cctgtgatat
    19141 tgctgtttat ggacatattc accagcagtt gcttcgttac gggactggtg ggcaattgat
    19201 tgtcaatccg ggttcgattg gccaaccttt ctttttggac gctcagctac ggaaggactt
    19261 gcgggcccag tatatgattt tggagtttga tgacaaaggc ctggtagata tggacttccg
    19321 acgggtagac tacgatgtgg cagcggaatt gcagctggct aaagacctga gacttcccta
    19381 ttttgaggtt tactatgaaa gtctggtcaa tgggatccac catactcatc atcaggaatt
    19441 tttgagagaa ttggctcaga aagagggctg cgatcgggag ttagacgact ggttgaaaag
    19501 tggtaacgat tgacattaca actaaaaagg gtataataat agaaaaagaa gagtagaggc
    19561 agggtagcct cgtaaaaagg agaagaggat gcaaattcca agtagattta ccattgcaac
    19621 tcatatgctg ataatcattg ccctcgaggg gaaggaaagc aaggtgacca gtgattttct
    19681 ggctgctagt gttggggtca atcctgtcat tatcagaaag atcttgtccc agttgaagaa
    19741 ggcagagctg atttcagtag cgcgtggaac gggcggaaca gagattgtca aggaccttaa
    19801 ggatattagt cttttagatg tttatcaggc ggtcgaatgt cttggtaaga caggtcaact
    19861 cttcagtttc catgacaatc cgaatccaaa ttgccctgta ggagctcata ttcatgatgt
    19921 tttggatcaa aaattggaga gaattcagtt gactatggag gcagaacttg gtcagaccag
    19981 tctagaaaaa gtcgtggccg atgcagagag tcagatgaag gattaagagg gataaatgcc
    20041 ctcttttttt ctttggataa ttatgataaa atgtagctat taaaggagta agaaatgtat
    20101 ctcgttatag aaattgtatt agcctttata gtgtcatttt ggaaggataa tagaagtttg
    20161 tggaatccag tattattttt attatccctc atttcaagtt atttttatct atcctacctt
    20221 ttttataaaa atggatacga gaatgttcag ttagcttttt atgtatttgc ctttgtctta
    20281 cttccttttt tgctttttct aagtggcatc tttttaatct atagtggggt cattttgttg
    20341 aaacgagagg gacgttccaa gccccattat ctctcaatgc tctttgattt ttattgacta
    20401 ttagattcta tttaaaaaga cttagaatgc acatgaaagt atgtattcta ggtcttttgt
    20461 tttgtataca tttaattttc aagagtatta tctatttttc catgcatggt aacgagtatc
    20521 aatcaataac tgggtaaggc gacccaaggt ttctctttct tctggagtga gggattgagc
    20581 ttggacaaag agatgatgaa tgtattcaag cgcctttaag gaagccaagt cattgataga
    20641 gctaatacca gcatcaagaa tagtgccaaa gaagaggtcg aagtagagct gaagttcttc
    20701 gtcagggact gtggccaccc attctttaaa ggttgtgtct acttgccggc tatcactgtt
    20761 ggtcttatcc agttgaacga agtgcttgtc ctcaatcttc caattaaagg tatcgtgctg
    20821 ggcgatgcca cccagggcag tactctgaac gatgatttgg tgagcaggaa tttccagcat
    20881 cataccgata atggaacctt gtggaatgaa tatcttgctt ctatccatta tcctttgata
    20941 acccgcagtc tgtgtcaatt cttgatggag accaggtgca tcaaatgtat aaactgctgt
    21001 gatctgattt tgcaaacttt gctcaatttg gctagcagca tagatagcga gatttcctcc
    21061 cttggaatgc ccagccagaa taaccttttg cttaggatga tgggcaaaaa agttctttaa
    21121 atagcgaagg gcgtgctttt gagcaggaat ttccttcata taggtcaggt ggaaatcttc
    21181 cttccagcca atgatactgt catctgtccc acgaaagaca atcagatagg tatcgaggct
    21241 gacacgataa gtcatagccg caaattgctt ttgcagttca gggtcgatgt cgttgataaa
    21301 atgggagagt ttgcaatttt tgaagcgctt gtgttgagcc aattcatcta ataattgaag
    21361 gcgatttttg ctagtaagca tggtgggctc tcttggaacc tgaggtgcta gatctaaaag
    21421 acgttgagga agtgtggaga ccagattatc aaaggagagg taggtgattt ctattaaggt
    21481 tagaatgtct aactcattca agggaaggtc gtaataagaa tcatatgcga catctttcag
    21541 atagtcaaaa atattggcca taagagctcc tttcttttta tttatcttag caaatttccc
    21601 tcaaattagc tagtagcatt gcctgtttgt actggctaaa aacaggctat ttcaaattca
    21661 gtttcagacc atctggcatg gaaaaatctg ttataataat ggaaaaggag aagcgcatgc
    21721 acaagatttt attaatagaa gatgatcagg tcattcgtca acagattggg aaaatgctct
    21781 ctgaatgggg atttgaagtg gtcctggtag aagactttat ggaagttttg agtctatttg
    21841 ttcagtcgga acctcatctg gtcctcatgg atattggttt gcccttgttt aatggttatc
    21901 actggtgtca ggaaatccgc aagatttcca aggtacctat catgtttctt tcttcgagag
    21961 accaggctat ggatattgtc atggcaatca atatgggggc ggatgacttt gtgaccaagc
    22021 cttttgacca gcaggttctt ttagctaagg ttcagggctt gttgcgtcgt tcctatgagt
    22081 ttgggcgtga tgagagtttg ctggaatatg ctggtgttat cctcaatacc aaatccatgg
    22141 atttacatta tcaagggcaa gtcttgaatt tgaccaagaa tgaattccag attttacgcg
    22201 tgttatttga gcatgcaggc aacatcgtag cacgtgacga cctgatgcgg gaactttgga
    22261 acagtgactt tttcattgat gataataccc tctctgtcaa tgtggctcgt ttgcgtaaaa
    22321 agttggagga gcagggattg gtaggattta tcgagaccaa gaaaggaata gggtacggat
    22381 tgaagcatgc ttgattggaa acaatttttt ctagcctatc tgcgctcccg tagtcgtctt
    22441 tttatctatc tgctttcttt ggcatttctt gtcttactct ttcagttttt atttgccagt
    22501 ctaggaattt acttcctcta ctttttcttc ttgtgttgct ttgtaaccat cttatttttc
    22561 acttgggaca tattggtgga aacgcaggtc tatcgccagg aacttctcta tggagagagg
    22621 gaagccaagt ctcctttgga aatagcttta gcagaaaaat tagaagcgcg tgagatggaa
    22681 ctctatcagc agaggtcaaa agcagaaaga aaactgacgg atttgctgga ttactatacc
    22741 ttgtgggtcc atcagataaa gacccccatt gcagccagtc aactcttagt tgcagaagtg
    22801 gtcgaccgcc aactgaagca gcagctagaa caggaaattt tcaaaatcga ctcctatacc
    22861 aacctagttt tacagtacct gcgtttagaa agtttccatg atgatttgct cttaaagcag
    22921 gttcaaattg aggacttggt caaggaaata attcgtaaat atgctctttt ctttattcaa
    22981 aaaggcttaa atgtcaatct acatgacctt gataaagaaa tcgtgacgga taaaaaatgg
    23041 ctgctagtgg ttattgagca aatcatctca aacagtctca agtacaccaa ggaaggtggt
    23101 ctggagattt atatggatga ccaagagctt tgtatcaaag atacgggaat cgggataaaa
    23161 aacagtgatg tcctccgagt atttgaacgt ggcttttcag gatacaatgg ccgtttgacc
    23221 cagcagtcct ctggacttgg cctttatcta tctaagaaaa tttctgaaga actggggcac
    23281 cagattcgta tcgagtctga ggtcggaaaa ggaacgacag tgcggattca gtttgctcaa
    23341 gtgaacttag tccttgagta aaaatagatg agaaaaagcc tccagattgg aggcttttat
    23401 gctagactct tatttctcaa cgcgtgattt gttggcgata tcagctagga tagcttgaac
    23461 aaaattatca actgagacag tttgtgtttc tttttggccg tagcgacgaa cgttgactgt
    23521 ttcgtcttcc atttctttgt ctccaacaat taattggtaa ggaatcttgc tggtttgtga
    23581 agcacggatc ttgaactgca ttttttcatt gcgctcatct acgtctgcac ggacaccgcg
    23641 gtcacggagt ttcttggcca cttcccaagc gtagtccacg tgtttttcgt tagatactgg
    23701 gatgagggtt acttggtgtg gtgccagcca tgttgggaag gcccccttgt agttctcaat
    23761 caagatagct gtgaagcgtt ccatagttga gataacccca cggtggatca tgactggacg
    23821 gtgatcttcg ccatcagctc cgatgtattt gaggtcgaag cgttctggca acaagaaatc
    23881 aagttggata gtagaaaggg tttcttcttt tccaagggca gttttaatct ggatatccaa
    23941 ttttggtccg tagaaggctg cttcaccttc ggcttcaaag tagtccacgc ccatttcatc
    24001 aagagctgca cgaagcatgg tttgggcatt ttcccacatc tcatcgttat caaagtactt
    24061 atgagtatct tgagggtcac gaagagagag gcggaagcgg tagtcagtca agttgaagtc
    24121 ttcataaaca tcgataatca actgaagggc acgttggaat tcttcttgga tttgttctgg
    24181 agtaacgaat aggtgaccgt cgttgagtga catttcacgt acacgttgaa ggccagtgag
    24241 ggcaccagat ttttcgtaac ggtgcatcat accgatttca gcgatacgga ttggcaattc
    24301 acggtaagag tgaacatggt gtttgaaaac ttggatgtgg tgcggacagt tcattggacg
    24361 aaggacaaat tcttccccgt cacccatgtc catggttggg aacatgtctt cttggtaatg
    24421 atcccagtga ccagaagtct tgtaaagctc aacagaagca agtggtggag tgtagacgtg
    24481 ttggtagcca gaagccaact ctttgtttac gatgtagcgt tccaattcac gacggatagt
    24541 cgcaccattt ggcaaccaga acggcaaacc ttgtcccact tcttgtgaaa tcataaagag
    24601 gtcaagctct ttaccaagtt tacggtggtc acgttcctta gcttcttcac gcatttgaag
    24661 gtagtttttc aagtctttct tgtcaaacca agctgtaccg tagatacgtt gcatcatagc
    24721 gttgtcgctg tttccacgcc agtacgcacc agctacatgg agaaggtgga agatttggat
    24781 acgacctgtt gatggaacgt gaggtccacg gcagaggtct acatattcac cctgacgata
    24841 gatagtcaaa ccgccttcgt cttctgagtg ttcttcaatc aattccaact tgtaagggtc
    24901 atttttgaag atttcacgtg cctcgtcttt agtcacttct tcacgaatag atgggaagtt
    24961 ttctttgacg attttttgca tttcttcttc gatacgagga aggtcttcgt tagagatttg
    25021 accagctgtg ttgtcagtat cgtagtagaa accatcttcg atggctggac caactcccaa
    25081 gtgaatgtcc gggaaaagac gacgagctgc ttgggcgaac aagtgagctg ctgagtgacg
    25141 caagattgga agggcatctt cgtgatcagg tgtcacaatt tcgatgcttc catcttcagt
    25201 gatagcgcga gtagtgtcga tgagtttgcc gttgaattta ccagccaagg cttttttagc
    25261 tagggaattg ctgatagatt gggcaatttc aaaagttgtt acgccagatt cgaattcacg
    25321 aacagcgcca tctgggaaag taatgttaat catgatgttc tcctttttta ttatttcata
    25381 gtttctaagc attgattttt tatcagcaga ctacttccga gtcctaacgt tcaattgctt
    25441 ttctttatca gagaggaagt tttccatttc cgtcagaatg tctatatcca aacgttgaga
    25501 aagttctaat agccaccaga tattttctga aagtttttgt tccagtgtgt agggtgtttc
    25561 atcatagtag cgtccttgct ttgtcatcac cagtcattgg aaatttccaa tatcattaga
    25621 taaagccaag aggtcttctt ctaccgtcca cttgaaatca tgatgcttaa cttccagttc
    25681 gtgataagct tgtcggattg cccaactgcg ctccactaat tcttgcaact ccataattag
    25741 tatcctaata aaaaaatgcg acatcctcga aaggacgtcg caacgtggtt ccaccttcat
    25801 ttatgtacct caaaagagag ggacacctct gatcggctct aacgtggcca ccgttttatg
    25861 ttttcataaa aaactcaaga gtagtatcag tttagacttc ctatgcgttt ccagcaacca
    25921 cgcactctct agtagaaagg gactaagtga cttgtctcta tggattatta tagcatgatt
    25981 gtgagatttt tcaaggattt tgtgaaagtt ttttgttttt cattttttgt agaatatgct
    26041 tgatgctaat accagaatcc atgctcacca gagcaactgt ttcatagatt agcaagtaaa
    26101 ttagtataaa ctcaccaaag gttatgatag taaagtaaaa gagcagtccg ttaccaacta
    26161 accaccaaag tgagaaacgg aaacggtagc tatagagtaa cgatataatc aagattacca
    26221 gaggtgtaaa gaagagaaga ttgtttatat agagtccctt gagtgtaagg gggtcagaaa
    26281 caactagcaa gaacaactca taaagtggcc aataaaagaa taatatgacc agatagtagg
    26341 ggagatggga atagaatcta cgcatgataa tcacctcgtt ttaaaaaaac agacaactta
    26401 gatctcttgc tatgattatt atagcatgtt taaaacaaga aagtaaattt gttgacaaag
    26461 aagatttttc ttttccctag aatcatagtt agttttcttg gtagaaatat tttgataata
    26521 attaagcaag actattgaca ttgattatta agagtgtcac aattgttgta actaaaataa
    26581 ttacaacaag agaggtataa aaaatgaaac tagcagttat tgcagcaaat ggacaagcgg
    26641 ggaaggcaat tgttgaagaa gcagtcaaac gaggacatga agtaacggct attgttcgtt
    26701 ctgaaaacaa aagtcaatct gagtctatta ttaaaaaaga tttatttgag ttgacaaaag
    26761 atgatcttac tggatttgat gctgttattt cagcgtttgg tgcttataca ccagatacgc
    26821 taccgctcca cagcaaatca atcgaactat ttaatcagct tcttgctgga acacagacac
    26881 gttttctagt tgtaggggga tcaggaagct tttatataga tgaaacaaaa acgacacgac
    26941 ttttagatac gtctgatttt cctgaagaat ttaagccact agcaaaagct caagcggatg
    27001 aattggatct tcttcgtaca aaaaataatc tcaactggac ttttgtcagt cctgctgtag
    27061 attttattcc cgatggtgaa aaaacaggaa actacattct agcaggagaa atttttacta
    27121 ctaatgaaaa aggaataagc cagattagtt atgcagatta tgctattgga ttggtagatg
    27181 aacttgaaaa aggtcatcat ataaaagaac gtatctcttt acttgaaaaa taataactat
    27241 gagagtatta atgtttgaca gaaaatttaa atcttggtag aatagggatt gtcgtaaaga
    27301 caaataactt cttcttggtt acaggcatgc caacctgtca ctcggatgaa gccaaataaa
    27361 aaggagaaac atcatggcaa tctcaaaaga gaaaaaaaat gaaatcatcg cacaatatgc
    27421 acgtcacgaa ggtgatacag gttcagtaga ggttcaagtt gctgtcctta cttgggaaat
    27481 caaccacctt aatgaacaca tcaaacaaca caaaaaagac cacgctactt accgtggatt
    27541 gatgaaaaaa atcggtcgcc gtcgtaactt gcttgcatac ttgcgtaaaa acgacgttaa
    27601 ccgttaccgt gagttgatca actctctagg acttcgtcgc taattcaaga tacaaaggct
    27661 gtcaaaagca caaagtaaaa ataggaaaat tgacgaagaa acttcagttt ctaggagatt
    27721 ttatcttttt tgccaagtgc ttaggccgta ttcaattgag catatcttga taatgaagct
    27781 actctaaatt gggtagcttt tttgtgttgt caccttacct cgatatactc aagtataatc
    27841 tttggttacg gttcctagca ctgtaaggta aaataaacca gcttttctcc cttcggggag
    27901 atttttttgt ttcactgaaa gtttcgtacg atcttcgcct cgtcgcctag tctataaacg
    27961 atttatctag caagaatcat gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa
    28021 tgacacagtg ttcgatgagc acaaggagtt tcatcttttt cactaggatt ttagcccgga
    28081 ctcaaatcag ctctctgact tcagagggct tttttattga ggttttatcg gtaacaattt
    28141 tggagactac aaaaacctca aacggtatca gctaattaca ccataaaggt gcgcagttac
    28201 tcggcttttc aagccgagta gttgtatgca agccccctag aagagcccac tctttacaaa
    28261 gtaaagtata gtatgttata ctttacatgg aagtagtcac tgaattccag ttagaaatta
    28321 ctttgtaact acgttttgag gaggagtaaa atgctttcct acgttcgata ttacccacta
    28381 gcgatagcta aattaatgtg tctgtgctct cctaaaatct gctgatttat tactgactaa
    28441 tacaggagtt ttttttatgg gacagacaat catatctgct attggtgttt atatttccac
    28501 cagtatcgat tatttaatta ttttaattat tttatttgca cagctatcac agaataaaca
    28561 gaaatggcat atttatgcgg ggcaatatct aggcacaggc ttacttgtag gggcgagttt
    28621 agttgctgct tatgtcgtta atttcgtgcc tgaagaatgg atggttggat tgcttggttt
    28681 aatccctatc tatttaggga ttcgctttgc aattcttgga gaagatgcgg aagaagaaga
    28741 ggaagaaatt attgaaagat tagaacaaag caaggcaaat caactgtttt ggacagttac
    28801 attgctgaca attgcgtctg gcggagataa tttaggtatc tatatacctt attttgcttc
    28861 gttagattgg tcacagaccc tcgtggcctt gcttgtgttt gtaatcggca taattatctt
    28921 ttgcgagatt agtcgggtgt tatcctctat tccgttaata ttcgagacaa ttgaaaaata
    28981 cgagcgaatc attgtgccct tagtattcat tctacttgga ctatacatca tgtatgaaaa
    29041 tggcacgata gagacttttc tgatcgtgta gatttttttg tttcactagg attttagccc
    29101 gagctcaaat cagctctctg attttcagag ggctttttca ttgagtataa atggacaatc
    29161 ttaaagttac tctattgtag agtggctttt gatttgatta ggagattctt ataaatatag
    29221 taaaatgaaa caaaaacagg acaaatcgat caggacagtc aaatcgattt ctaaaaatgt
    29281 tttaagaagt agaggtgtac tattctagtt tcaatttgat atataaatga aaaccttagc
    29341 tgtttggcca aggttcattt cttctatgca agttcttctc ttttcttatc tgggttccag
    29401 atgaagcttg cgataaagct aaagatgatg gttaggatag cgaggataat agcaaggatg
    29461 agggcaggga tgcggataaa ccaccagagt ggatttggtt ttttatcatt gtgccattgt
    29521 ttcgtttctt cgtccagacg ttggaattct gtttgaatac gattggcgac tgtttcaatg
    29581 ccttcatcat tcattttctt gatatctgag atatcgattg gatttccaaa gttcatatcg
    29641 acacgttcac ggctaatcaa gcccttcaaa gtcatgggac cggtgtaggt aaccggcatg
    29701 atacggactt tggccatttt ggcaatcagt gctgcgcccc ccttgacatc gtttgagtgg
    29761 cggctaccac ttggaaacat gatgagagag cggtcacttt ttttgagaac gttgatagga
    29821 tatttgatgg ctgaggcgct gggattttca cggtcgatgg gaaaggcgcc acacatacga
    29881 atccaccaac caaagatacg gttggtaaag agttcttttt ttgccataaa gatgaactgt
    29941 tttggcttgg tcgcaaaggc catataaaca ggatcccacc aggtacggtg aggcgcaact
    30001 aaaatataat tttcatcttg attaggaatt ttatcagtat tatgatagtg agcattgcca
    30061 ttgatggacc ataagagcaa tacaactaat ccacgcaaat aagtataaaa catgcgatct
    30121 ccttcgattg ttttcttgtt attattatac cttatcaaag gagggctggc aaacttttcc
    30181 cttgactaga tgcatatttg ggatgaaatt agaattttgt taaaaaaaat gatataatag
    30241 aatttatgga taaaaataag attatgggat taacccaaag agaagtcaag gaaagacagg
    30301 ctgagggttt ggtcaatgac tttaccgcat cagccagtac cagcacttgg caaatcgtta
    30361 aacgaaatgt ctttaccctt tttaacgctt tgaacttagc cattgctttg gctcttgcct
    30421 ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat ctgctttaac gctttttctg
    30481 ggattgtgac cgagctacga gccaaacaca tggtggacaa gctcaatctc atgaccaagg
    30541 aaaaggtcaa aaccatccgt gatggtcagg aagttgctct taatcctgaa gaattagtgc
    30601 taggagatgt cattcgtttg tctgcaggag agcagattcc tagtgatgcc ttggttttgg
    30661 aaggctttgc ggaagtcaat gaagccatgt taacgggaga aagtgatttg gtgcaaaagg
    30721 aagttgacgg cttacttttg tcaggaagtt tcctagccag tgggtcagtt ttatctcaag
    30781 ttcaccatgt cggtgcagac aactatgctg ccaaactcat gcttgaggct aagaccgtta
    30841 aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt ggctggtttt actgggaaga
    30901 ttatcattcc ctttggtctg gctctcttgc tggaagcctt gcttttaaaa ggcctgcctc
    30961 tcaagtcatc tgttgtaaac tcgtcgacag ctcttttggg aatgttgcct aagggaattg
    31021 cccttttgac cattacttcg ctcttgactg cagtgattaa gttgggcttg aaaaaggtct
    31081 tggtgcagga gatgtactct gttgagacct tggcgcgcgt ggatatgctc tgtctggaca
    31141 agacgggcac catcacccaa ggaaagatgc aggtggaggc tgttcttcca ctgacggaaa
    31201 cttacggtga agaggctatt gccagcatct tgactagcta catggcccat agtgaggata
    31261 agaatccaac tgcccaagcc attcgccagc gttttgtggg agatgttgct tatcctatga
    31321 tttccaatct tcccttctcc agcgaccgca agtggggggc tatggagtta gaaggcttgg
    31381 ggacagtttt cttaggggca cctgagatgt tgctggattc tgaagtccca gaagccaggg
    31441 aggccttgga gagaggatca cgtgtcttgg tcttagctct cagtcaggag aaattagacc
    31501 atcacaaacc acagaaacca tctgatattc aggctctagc cttgctggaa atcttggacc
    31561 ccattcgaga gggagcagca gagacgctgg actatctccg ttctcaggag gtgggactca
    31621 agattatctc tggtgacaat ccagttacgg tgtccagcat tgcccagaag gctggttttg
    31681 cggactatca cagctatgta gattgctcaa aaatcaccga tgaggaattg atggccatgg
    31741 cggaggagac agctattttc ggacgtgttt cccctcatca aaagaaactc atcatccaaa
    31801 cgttgaaaaa agcgggtcat acaacggcta tgacagggga cggggttaat gatatcttgg
    31861 cccttcgtga ggcggattgt tctatcgtga tggcggaggg ggatccagca acccgtcaga
    31921 ttgccaatct ggttctcttg aactcagact ttaatgatgt tcctgagatt ctcttcgagg
    31981 gtcgtcgcgt ggtcaataac attgcccaca tcgccccgat tttcttgata aagaccatct
    32041 attccttcct gttagcagtc atctgtattg ccagtgcttt actaggtcgg tctgaatgga
    32101 tcttgatttt ccccttcatt ccaatccaga ttaccatgat tgaccagttt gtggaaggtt
    32161 tcccaccatt cgttctgact tttgagcgaa atatcaaacc tgttgagcag aatttcctca
    32221 gaaaatccat gcttcgtgcc ctaccaagcg ctctcatggt cgtctttagc gtcctgtttg
    32281 tgaaaatatt tgggagtagc caaggttggt ctgagttaga aatctcaact ctcctctatt
    32341 atctcttggg gtcaattggt ttcttatccg tatttagagc ctgcatgcca tttaccctat
    32401 ggcgtgtcct cttgattgtt tggtcagtag gaggtttcct agccacagct ctcttcccaa
    32461 gaatccaaaa actgcttgaa atttcaacct tgacagaaca aacgttgcct gtttatggtg
    32521 tcatgatgtt ggtctttaca gtgattttca tcctgactag tcgctatcaa gctagaaaat
    32581 aaagaaagac tgcaatctgt ggattgcagt ttttttaggt acaagattgc cagccgaaat
    32641 gtggtataat aagaggtaat agagttttgg aaagtgagag aagatgattt caaagagatt
    32701 agaattggta gcttcctttg tgtcacaggg ggctatttta ctagatgtgg gaagtgacca
    32761 tgcttatctg cctatcgagt tggttgagag aggccaaatc aaaagcgcta ttgcaggtga
    32821 ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt gaggctcacg gcctaaagga
    32881 gaaaatccaa gtccgtttag ccaatggctt ggcagctttt gaagagactg accaagtgtc
    32941 tgtcattacc attgctggca tgggtggtcg tttgattgct aggattttag aagaaggttt
    33001 ggggaagtta gctaatgtag agcgtttgat cctccagccc aataatcgtg aagacgactt
    33061 gcgtatctgg ctacaggatc atggattcca gattgtagca gaaagcatct tagaagaagc
    33121 tggaaagttt tatgagattt tggtggtgga agcaggacaa atgaagctat cagccagtga
    33181 tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca gtatttgtcc aaaaatggca
    33241 aaaagaagct gagaagctag agttcgccct cggacaaatc ccagaaaaaa atctggaaga
    33301 acgtcaagtt ctagtagata agattcaagc tatcaaggag gtgctccatg ttagcaagtg
    33361 aagtgatcca agcttatgaa gccttttgcc ctcaggaatt ttctatggag ggagacagcc
    33421 gtggtctgca aattggcact ttagacaagg gtatccaaag ggtcatggtt gccctcgata
    33481 ttcgtgaaga gacagtggca gaggccattg aaaagggtgt ggacttgatt atcgtcaagc
    33541 acgcgcctat ctttcgtcct atcaaggact tgcttgccag ccgtccgcaa aatcagattt
    33601 acatcgacct gattaagcat gatatcgcag tttatgtcag ccataccaat attgatatcg
    33661 ttgaaaatgg gctcaatgac tggttttgtc agatgctagg aatcgaggag acgacttatc
    33721 tgcaggaaac aggtccagaa cgtggaattg gacgtattgg gaatattcag cctcagacat
    33781 tttgggaatt ggcccaacag gtcaagcaag tctttgacct agatagcctt cgaatggtgc
    33841 attatcaaga ggatgatttg cagaagccta tttcaagagt agcaatttgt ggtggaagcg
    33901 ggcagtcttt ctataaggat gctttggcaa agggggcaga tgtctatatc actggtgata
    33961 tctactacca tactgctcag gatatgctgt ctgatggctt gttagcattg gatccaggtc
    34021 actatatcga agtgcttttt gtggaaaaaa tcgcaacact ccttactcaa tggaaagaga
    34081 aaaaaggctg ggaactagag attttaccta gtcaagcatc gaccaatcct ttccgtcata
    34141 tctagttaga aagtgaagac aatgaaaaaa gttgccatta ttggagcagg aattgtggga
    34201 gcaacagctg cctactacct ctcgagagaa agtgacctag aggtgaccgt ttttgaccat
    34261 gagcaaggtc aagccaccaa ggccgcagca ggaattatca gtccttggtt ttccaaacgc
    34321 cgtaataaag cctggtacaa gatggcgcgc ttgggggctg atttttatgt ggatttatta
    34381 gctgatttag agaaatcagg acaagaaatc gacttttacc agcgttcggg agtctttctc
    34441 ttgaaaaagg atgaatccaa tttggaagaa ctttatcaac tggccctcca gcgcagagaa
    34501 gaatctccct tgatagggca attagccatt ctgaaccaag cctcagctaa tgaattattc
    34561 cctggtttgc agggatttga ccgcctgctc tatgcttctg gtggagcgag agtagatggc
    34621 caacttttag tgactcgttt gctggaagtc agtcatgtca agctggtcaa agaaaaagtg
    34681 actctgacac cgttagcatc aggctaccag attggtgaag aggagtttga gcaggttatt
    34741 ttggcgacgg gagcttggtt gggggacatg ttagagcctt taggttatga agtggatgtt
    34801 cgtcctcaaa aaggacaact acgagattat cagcttgccc aagacatgga agattaccct
    34861 gttgtcatgc cagaagggga gtgggatttg attccctttg caggtgggaa attatcctta
    34921 ggcgctaccc acgaaaatga catgggattt gatttgacgg tagatgaaac cttgctccaa
    34981 caaatggagg aggccacctt gactcactat ctgattttgg ctgaagctac ttcaaaatct
    35041 gagcgtgttg gaatccgtgc ctacaccagt gatttctctc ctttctttgg gcaggtgcct
    35101 gacttaactg gtgtctatgc agccagtgga ctaggttcat caggcctcac aactggtcct
    35161 atcattggtt accatctagc ccaactgatc caagacaagg agttgacctt ggaccctcta
    35221 aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg aataatactc aataaaaatc
    35281 aaagaacaaa ctaggaaact agccgcgggt tactcaaagc actgctttga ggttgtggat
    35341 agaactgatg aagtcagtaa ccatacccat ggcaaggcga cgttgacatg gtttgaattg
    35401 gattttcgaa gagtataagc attttactga aattttatca ggtagtttag gatggcaaat
    35461 gacattccct gtcaaaaatg gtaaaataag aaaaaataat ctgagaatcg aggaaaaaag
    35521 atgcaagaaa agattttggt aactggtggt gccggtttta ttggaaccca cactgttatt
    35581 gaattgatcc aagcaggcca tcaagttgtt gtggtggata atcttgtcaa tagcaatcgt
    35641 aagagtttag aagttgttga aagaatcaca ggagttgaga ttcctttcta tgaggcagat
    35701 attcgtgaca cagataccct cagagatatt ttcaagcagg aagaaccgac tggtatcatt
    35761 cactttgctg gtttgaaggc tgttggcgaa tcaacacgta tccctcttgc ctactatgac
    35821 aacaatatcg ctggaactgt cagccttttg aaagccatgg aagaaaacaa ctgtaaaaac
    35881 atcatcttca gttcttctgc gacagtttac ggggatccgc acacagtgcc catcttggaa
    35941 gatttcccac tttcagtgac caacccatac ggtcgtacta agctcatgct agaggaaatt
    36001 ttgactgata tttacaaagc agactcagaa tggaatgttg tcttgcttcg ttactttaac
    36061 ccaatcggag cccatgagag tggtgatttg ggagaaaatc caaacggtat tccaaacaat
    36121 ctcttgccat atgtgactca agtagccgtt ggaaaattag agcaagtgca agtgtttgga
    36181 gacgattacg atacggaaga tggaacaggt gttcgtgact atatccacgt tgtcgatttg
    36241 gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag gttcaggact aaacgtttat
    36301 aaccttggaa ctggtaaagg ttactcagtt cttgaaatta tccaaaacat ggaaaaagcg
    36361 gtgggccgtc ctattcctta ccgcatcgta gaacgtcgcc caggtgatat cgctgcctgc
    36421 tactcagacc cagcaaaggc taaagcagaa ctcggttggg aagcagaact cgacatcacc
    36481 caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc caaatggatt tgaagactaa
    36541 gatgatgatt tcaatcatcg tcccttgttt aaacgaagag gaagtacttc ctctttttta
    36601 tcaggctctg gaagctttac ttccagattt ggaaacagaa atcgagtatg tctttgtcga
    36661 tgatggatca agtgatggga ccttggaact cttaaaggcc tatcgggagc aaaatccggc
    36721 agtccattat atttctttct ctcgaaattt tggcaaagaa gcagcccttt atgcaggctt
    36781 gcaatatgcg acaggagatt tggtggtggt gatggatgca gacctccaag atcctcctag
    36841 tatgttgttt gagatgaaaa atgtactaga caaaaatgta gacttggact gcgttgggac
    36901 acggagaact agtcgggagg gagaaccctt ctttcgcagt ttctgtgctg ttctctttta
    36961 tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg ggtgtccgtc attttcgtat
    37021 gatgagaagg tctgtagtcg atgccatttt aagcttgacc gagtccaatc gtttttcaaa
    37081 ggggctcttc gcctgggtgg gtttcaaaac ctactatttg gactatccaa atgtcgaaag
    37141 gcaggctggc aagacaagtt ggagttttag gcaactcttt ttctactcca ttgaagggat
    37201 tattaatttt tcagatttcc ctttgactat agcctttgta gctggtctcc tatcttgttt
    37261 tctttctctg ctgatgacct tttttgttgt ggttcggatc ctcattttgg gcaatccgac
    37321 atctggttgg acctctctga tggctgttat tctctttctt ggaggcattc aactcttgac
    37381 cattgggatt ctcggtaagt atatcagtaa gatttattta gagactaaaa aaagaccact
    37441 ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag
    37501 actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta
    37561 ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagacatc
    37621 ctgactagga gaaatttctt tttccagttg gtcagggcca tcgtaaaaac gcacgattcc
    37681 attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg
    37741 ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa
    37801 aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa
    37861 tcaagagcag ggcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt
    37921 ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc
    37981 tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca tgattctgat
    38041 gcaagtgtag tacaaatctc atcttcaagc agttctcatc ctgagcagag ttcagagcca
    38101 gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc
    38161 gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag
    38221 gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg tgatgttata
    38281 aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca
    38341 gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata
    38401 caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag
    38461 aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa
    38521 ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg
    38581 aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt
    38641 ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa
    38701 ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag
    38761 cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa
    38821 aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac
    38881 aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa
    38941 aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg
    39001 gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa
    39061 ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat
    39121 tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag
    39181 tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc
    39241 gatgccaacg gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa
    39301 gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta
    39361 gaaggcgatc acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca
    39421 gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta
    39481 tcttcttgtt tctagcggct tttacgggag tttatcttga aattactagg catggtggtt
    39541 ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt
    39601 atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct
    39661 taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg
    39721 cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca
    39781 tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc
    39841 cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg
    39901 ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc tttttgaatg
    39961 tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg
    40021 tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt
    40081 cgaaaatctc ttcaaaccac gttagtttcc atctgcaacc tcaaaacact gttttgaaca
    40141 acctgcggct agctttctag tttgctcttt gattttcatt gagtatgaga tacaagggat
    40201 tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat
    40261 ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca
    40321 atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat
    40381 ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga
    40441 gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt
    40501 agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag
    40561 cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt
    40621 tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca
    40681 aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc
    40741 tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc
    40801 ctatagtgct ggatttttgg tgatgcccct ttatctgctc tttgtccctt atggaaaatc
    40861 aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg
    40921 cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac
    40981 catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt
    41041 tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat
    41101 ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat
    41161 cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt
    41221 tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa
    41281 actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac
    41341 cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat
    41401 cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc
    41461 ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga
    41521 ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt
    41581 ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc
    41641 aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag
    41701 tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct
    41761 tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt
    41821 tgctggcttt cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt
    41881 gaccagatta aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg
    41941 ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa
    42001 actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct
    42061 tgtggcagat gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt
    42121 ggatagagga cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc
    42181 actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac
    42241 cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag
    42301 tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt
    42361 gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc
    42421 agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc
    42481 agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac
    42541 tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct
    42601 tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat
    42661 ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc ttacgtgatg
    42721 tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct
    42781 tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca
    42841 aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt
    42901 atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta
    42961 aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga gcgccagcag
    43021 tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc ttttatgatg
    43081 gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgtt ggtgcaggtt
    43141 gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag
    43201 tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa
    43261 gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt
    43321 tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta
    43381 gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga
    43441 ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc
    43501 ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta
    43561 ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc tactttgatg
    43621 aatgactggg cagcagccct cccagaaatt ctaccaaatt ttatgcaaaa tatggtaggg
    43681 atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa
    43741 atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt gagcagcctg
    43801 aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag
    43861 tctttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta
    43921 gacagaaaaa atctaacttt tggggtgttt tattatgaaa
//
LOCUS       DAVFJR010000013        41265 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVFJR010000013 DAVFJR010000000
VERSION     DAVFJR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.013"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(117..2669)
                     /locus_tag="VU722_000928"
     CDS             complement(117..2669)
                     /locus_tag="VU722_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU1771934.1"
                     /translation="MKSFLKTYRIYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2731..4353)
                     /locus_tag="VU722_000929"
     CDS             complement(2731..4353)
                     /locus_tag="VU722_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1771935.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4559..5584
                     /gene="trpS"
                     /locus_tag="VU722_000930"
     CDS             4559..5584
                     /gene="trpS"
                     /locus_tag="VU722_000930"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU1771936.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQNIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPDNERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5736..7214
                     /gene="guaB"
                     /locus_tag="VU722_000931"
     CDS             5736..7214
                     /gene="guaB"
                     /locus_tag="VU722_000931"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU1771937.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7265..8362)
                     /gene="recF"
                     /locus_tag="VU722_000932"
     CDS             complement(7265..8362)
                     /gene="recF"
                     /locus_tag="VU722_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU1771938.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGYRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQNGKAAVNGN"
     gene            complement(8365..8733)
                     /gene="yaaA"
                     /locus_tag="VU722_000933"
     CDS             complement(8365..8733)
                     /gene="yaaA"
                     /locus_tag="VU722_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU1771939.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8892..10142
                     /locus_tag="VU722_000934"
     CDS             8892..10142
                     /locus_tag="VU722_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU1771940.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQGSLIERAYQNALLGKSSADFKSWITKLEQV
                     DKDDICRAANNVKLQAIYFMEGIE"
     gene            10139..11422
                     /locus_tag="VU722_000935"
     CDS             10139..11422
                     /locus_tag="VU722_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU1771941.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKEYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTSYLFSATDHFLENLDLLDELVTSAHFTEASILREQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTRFYKPVNMSLFLVGDFDVELV
                     QGYFERKELKDLDVQEVVREKFVLQAVKQTDSMRMEVSSPKLAIGVRGKREVAEADCY
                     RHHVLLKLLFAMMFGWTSDRFQKLYESGKIDASLSLEIEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11464..12285
                     /locus_tag="VU722_000936"
     CDS             11464..12285
                     /locus_tag="VU722_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1771942.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKGPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12296..12841
                     /gene="pgsA"
                     /locus_tag="VU722_000937"
     CDS             12296..12841
                     /gene="pgsA"
                     /locus_tag="VU722_000937"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU1771943.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12838..13665
                     /locus_tag="VU722_000938"
     CDS             12838..13665
                     /locus_tag="VU722_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU1771944.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13650..14489
                     /locus_tag="VU722_000939"
     CDS             13650..14489
                     /locus_tag="VU722_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU1771945.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14482..15276
                     /locus_tag="VU722_000940"
     CDS             14482..15276
                     /locus_tag="VU722_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU1771946.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15335..16153
                     /gene="mreC"
                     /locus_tag="VU722_000941"
     CDS             15335..16153
                     /gene="mreC"
                     /locus_tag="VU722_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU1771947.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSISKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16153..16647
                     /gene="mreD"
                     /locus_tag="VU722_000942"
     CDS             16153..16647
                     /gene="mreD"
                     /locus_tag="VU722_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU1771948.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16741..17919
                     /locus_tag="VU722_000943"
     CDS             16741..17919
                     /locus_tag="VU722_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1771949.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18143..18922
                     /gene="rpsB"
                     /locus_tag="VU722_000944"
     CDS             18143..18922
                     /gene="rpsB"
                     /locus_tag="VU722_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU1771950.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNS"
     gene            19001..20041
                     /locus_tag="VU722_000945"
     CDS             19001..20041
                     /locus_tag="VU722_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU1771951.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20287..20610
                     /gene="tnpB"
                     /locus_tag="VU722_000946"
     CDS             20287..20610
                     /gene="tnpB"
                     /locus_tag="VU722_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU1771952.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(20751..21059)
                     /locus_tag="VU722_000947"
                     /pseudo
     CDS             complement(20751..21059)
                     /locus_tag="VU722_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21050..21448
                     /locus_tag="VU722_000948"
     CDS             21050..21448
                     /locus_tag="VU722_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1771953.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(21645..22565)
                     /gene="cysK"
                     /locus_tag="VU722_000949"
     CDS             complement(21645..22565)
                     /gene="cysK"
                     /locus_tag="VU722_000949"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU1771954.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(22850..23485)
                     /locus_tag="VU722_000950"
     CDS             complement(22850..23485)
                     /locus_tag="VU722_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU1771955.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYASSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            23541..24839
                     /locus_tag="VU722_000951"
     CDS             23541..24839
                     /locus_tag="VU722_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1771956.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            24836..25498
                     /locus_tag="VU722_000952"
     CDS             24836..25498
                     /locus_tag="VU722_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU1771957.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            25578..26126
                     /gene="raiA"
                     /locus_tag="VU722_000953"
     CDS             25578..26126
                     /gene="raiA"
                     /locus_tag="VU722_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU1771958.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26262..28235
                     /locus_tag="VU722_000954"
     CDS             26262..28235
                     /locus_tag="VU722_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU1771959.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28232..28684
                     /gene="rplI"
                     /locus_tag="VU722_000955"
     CDS             28232..28684
                     /gene="rplI"
                     /locus_tag="VU722_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU1771960.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            28728..30080
                     /gene="dnaB"
                     /locus_tag="VU722_000956"
     CDS             28728..30080
                     /gene="dnaB"
                     /locus_tag="VU722_000956"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU1771961.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30082..30348
                     /locus_tag="VU722_000957"
     CDS             30082..30348
                     /locus_tag="VU722_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771962.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            30437..31783
                     /gene="cbpD"
                     /locus_tag="VU722_000958"
     CDS             30437..31783
                     /gene="cbpD"
                     /locus_tag="VU722_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU1771963.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      31866..31968
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32039..32329
                     /locus_tag="VU722_000959"
     CDS             32039..32329
                     /locus_tag="VU722_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU1771964.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32292..33050
                     /locus_tag="VU722_000960"
     CDS             32292..33050
                     /locus_tag="VU722_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1771965.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            33089..34096
                     /locus_tag="VU722_000961"
     CDS             33089..34096
                     /locus_tag="VU722_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1771966.1"
                     /translation="MKKTWKVFLTVLTALVAVVLVACGQGTASKDNKEAELKKIDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34096..34824
                     /locus_tag="VU722_000962"
     CDS             34096..34824
                     /locus_tag="VU722_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1771967.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            34943..35401
                     /locus_tag="VU722_000963"
     CDS             34943..35401
                     /locus_tag="VU722_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU1771968.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEINLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            35403..37835
                     /locus_tag="VU722_000964"
     CDS             35403..37835
                     /locus_tag="VU722_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1771969.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQVSALKLLANQGYDLEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            38156..38809
                     /gene="rr06"
                     /locus_tag="VU722_000965"
     CDS             38156..38809
                     /gene="rr06"
                     /locus_tag="VU722_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU1771970.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            38806..40137
                     /gene="hk06"
                     /locus_tag="VU722_000966"
     CDS             38806..40137
                     /gene="hk06"
                     /locus_tag="VU722_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU1771971.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            40220..40747
                     /locus_tag="VU722_000967"
     CDS             40220..40747
                     /locus_tag="VU722_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU1771972.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            40847..40978
                     /locus_tag="VU722_000968"
                     /pseudo
     CDS             40847..40978
                     /locus_tag="VU722_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            41025..>41265
                     /locus_tag="VU722_000969"
     CDS             41025..>41265
                     /locus_tag="VU722_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1771973.1"
                     /translation="MFASKSEKKVHYSIRKFSIGVASVAVASLFMGSVVHATEKEGST
                     QAATSSNMAKTEHRKAAKQFDEYINKMIQLDRRKDT"
BASE COUNT        12914 a         6702 c         8909 g        12740 t
ORIGIN      
        1 tcttagttca tagatctgaa ctttatcttc ataactcaat ttcataataa aacaccccaa
       61 aagttagatt ttttctgtct aacttttggg gtgcagttca ttaactagtc gattttttat
      121 gccttagatg actttcgtct gtgattatag attccaaata gtaagagaga agtaaaggaa
      181 cagattgctc cagtaataaa accattggga atgaaggaaa gtgtaatagt tcctttcccc
      241 ttgggaatgt caactttcat aaatccagtt tgagcttgtt taatttctat tttcttacca
      301 tcttggtagg cagaccaacc tttgtcataa ggaatggtga agaaaataga tgtatcttgt
      361 tggacatcat atgtagcaaa aaccttgttt ttagaagttg atactgtgac aggttgttct
      421 ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat
      481 tcaaatgata cttgtgaatt tccagggaaa ctaacattga tattgaaagt ttttttctct
      541 ttagtatatc ctagattaaa gaaggagaag acattatcag ttgtaaaagt ctttttttca
      601 ccatttacaa ggatgtcaac cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa
      661 gagagataaa cttggctgtt ttctggaact tcaatttgat actggattgc tgcatcttca
      721 tttgaagaac ttgtgacact aatcaaatca ttagtatttt ctattttttc tgttttttca
      781 taaggtattg gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc
      841 tgattatcca aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact
      901 gcaatcggaa gagagtattg attttcatat agggtaagat tatctttttg atagatatct
      961 ttaaagccat acttatcgat aggactgtct gagatattgt actggatacc aaataaacta
     1021 tcagccaaaa tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa
     1081 ccaagtttat ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt
     1141 ccattgtagt tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga
     1201 gtaaattgat ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa
     1261 gcacttcgag aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt
     1321 aaactcattt caaccagtat aaataaagag attagaatgg caaatagatt cacagatata
     1381 aactttttga taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc
     1441 agaatattca aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat
     1501 cctgctacta caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc
     1561 tttaagactt ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt
     1621 aaaaacatgt ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag
     1681 cttgcaatta gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat
     1741 ttcagcgtaa aaaataaaat ggtcaaaata aagggaagta gtccaacaaa aatcattggg
     1801 atggccccat actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga
     1861 taccagctac tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt
     1921 aaatcaaata gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata
     1981 actatgaaat caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga
     2041 taccagaaaa taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag
     2101 attgacagac ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca
     2161 gttataatta aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg
     2221 acagtgaaac tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata
     2281 gattgaaaca atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag
     2341 agagtggtca gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc
     2401 gcgagaaaac tacccaagta ataactagat agggcataga agtttagccc tagaccactt
     2461 gtaaaggtgt aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa
     2521 ataacgtatt gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata
     2581 ccttgagata gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag
     2641 attcgatatg tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt
     2701 ggttaaccca actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc
     2761 ttgtacttct gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc
     2821 atttttagat aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct
     2881 ggcaaagatg attgattctt taaagttttt caatccatca ttcaagcttg agatagattc
     2941 caagtccaag tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag
     3001 ttttgaaagc atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac
     3061 ttcatctcca gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc
     3121 ttctttactt gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc
     3181 tgagttatct tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc
     3241 atagtcaata tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc
     3301 aataagtgcc gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc
     3361 accatcaatc tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc
     3421 cgctttaaag ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat
     3481 cttatcaagc attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa
     3541 acgagcaacg aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc
     3601 tagcaattta gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag
     3661 tttgattttt ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg
     3721 gtcgtgggat actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt
     3781 aatcgattgg atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc
     3841 aaaaagtgct ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt
     3901 ttggtagtgt aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc
     3961 tgcttcccaa cctccaagtt cggcaaattc tccttcgagt tcggcagcac gaaccccgtc
     4021 ctcgtctgag aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag
     4081 tttttcattt cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt
     4141 ttgacgaaga acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc
     4201 gatatctcca gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa
     4261 tccgtaagta tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact
     4321 aaaacgtagt gaaacatcag atactgtaag caatattttt ctcctatatg tgtaatatat
     4381 ttattatact agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta
     4441 tatttacagt atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt
     4501 acggttattt cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat
     4561 gactaaaccc attattttaa caggagaccg tccaacagga aaattgcata ttggacatta
     4621 tgttggaagt ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt
     4681 gttcttggct gaccaacaag ctttgacaga tcatgccaaa gatcctcaaa acattgtaga
     4741 gtctatcgga aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac
     4801 tatttttatt caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct
     4861 agtttcgtta gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg
     4921 atttggagaa agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat
     4981 cacagctttc aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca
     5041 aactcgtgaa attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc
     5101 ggaaggtatt tatccagaca atgagagagc agggcgtttg cctggtttag atggaaatgc
     5161 taaaatgtct aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg
     5221 taaaaaagta atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa
     5281 gattgaggga aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca
     5341 agaaattgct gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa
     5401 gcgttatcta cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga
     5461 atttgctaag gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg
     5521 tgaagttgcg ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa
     5581 ctaagtttat tttacaagaa actatctttt ctatctcgaa gaaaagatag ttttttattt
     5641 acccctgtaa catttgacaa atttttatag aatggtatga tagatacaat ataaaaagaa
     5701 tcaagctcaa aaagaaagaa aagaggaaac ttcgaatgtc taattgggac actaaatttt
     5761 tgaaaaaagg ttttaccttt gatgatgtat tgcttattcc agctgaaagt catgtgttgc
     5821 ctaacgatgc agatttaaca actaaattgg cagataattt gactttaaat atcccaatta
     5881 ttaccgctgc catggacaca gttacagaga gtcaaatggc cattgctatt gctcgtgcag
     5941 gtggtctcgg agttatccat aaaaacatgt caattgctca acaagcagac gaggttcgta
     6001 aggtaaaacg ttctgaaaat ggagttatta ttgatccgtt cttcttgacg cctgaacata
     6061 caattgctga agcagatgag cttatgggtc gttaccgcat cagtggtgtt ccagttgttg
     6121 aaacacttga aaatcgtaaa ttggttggta ttttgacaaa ccgagatctt cgttttattt
     6181 cagattataa tcaaccaatt tcaaaccata tgactagtga aaatcttgtt actgctcctg
     6241 tgggtacgga tcttgcaacg gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc
     6301 cgttggtcga tgaagaaggc agtctttctg gtttgatcac tatcaaagat attgaaaaag
     6361 ttattgagtt tccaaatgcg gctaaagatg agtttggtcg tcttctagtt gcaggtgcag
     6421 taggtgttac ttcagataca tttgaacgtg cagaggctct ttttgaggca ggagcggatg
     6481 cgattgttat tgatactgca catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga
     6541 ttcgtgctca tttcccagat cggactttga ttgctggaaa tattgctact gctgaaggtg
     6601 cacgtgccct ttatgaagcg ggtgtagacg ttgttaaggt tggtattgga ccaggttcta
     6661 tctgtactac tcgtgtgatt gctggtgttg gtgttccgca agtaacagct atctacgatg
     6721 ctgcagctgt tgcgcgcgaa tatggtaaaa cgattattgc tgacggtggg atcaagtatt
     6781 ctggagatat tgtaaaagca cttgctgcag gtggaaatgc tgttatgctt ggatctatgt
     6841 ttgctggaac tgatgaagct ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga
     6901 cttaccgtgg tatgggatca attgctgcta tgaagaaagg ttcaagcgac cgttatttcc
     6961 aaggttctgt caatgaagca aacaagctcg ttccagaagg aattgaaggt cgtgttgctt
     7021 ataaaggagc ggcagctgat attgttttcc aaatgattgg tggtattcgc tctggtatgg
     7081 gttactgtgg tgcagctaac cttaaagaac tacacgataa tgctcaattt attgaaatgt
     7141 ctggtgctgg tttgaaagaa agccatcctc atgatgtgca aattactaat gaggcaccaa
     7201 attattctat gtaaaaaaca atgaaaagaa ctccagtgaa aacaggagtt cttttacaat
     7261 gttgtcaatt tccatttaca gcagctttac cattctgaat agtgaagata cttagatttt
     7321 ctggcagatt ttgaagatgg tctaagcttg ttgttgtgat aaaggtttgg attgattgag
     7381 aaatcgtttc taataatttt aactgtctag tgttgtcaag ttcactcatc acatcgtcaa
     7441 gcagtaatat cggagattct gtggtaatgc tttccattaa ttcgatttct gctaatttta
     7501 tagagaggac gagactacga tgttgacctt ggcttccgaa actagcatcc atcccattta
     7561 tataaaaaga aatgtcatct cgatgaggac cgacaccagt attcttttta aataaatctc
     7621 tggatctact tttttctaaa gcaattttga aagattcgga taagttttgt ttgtcagtta
     7681 tattgacaga agattgatag gatattgaca actcttcgat ctgattagag agttcaaaat
     7741 gtttcttacg cccaaatgat tctagttttt ttatgaaatc taagcggtga ttcattacac
     7801 gatatccata atcaactagc tgatcatcta acacagaaag gaatgtttca tctatttttt
     7861 gagctgattt taggtaagtg tttctttgct ttaggatgtg gttataattg gttaagtcag
     7921 ataagtagat tggcttaatt tgcccaagtt ccatatcaat gaattttcgt cgaatcgaag
     7981 gtgctccttt aattagttgt aaatcttcag gagcaaataa gacaacattc atgtgtccta
     8041 cataatctga aaggcgtgcc tgttttaagt gattaacttt tgttacacgg cctttttgtg
     8101 ttagttcgat ttctagggga atggatccag tttttttctg aacgagacct gaaagatgaa
     8161 gttgttcctc atcaaaatga atgagatttt tatctgttcg agttcgatga ctacgcgtta
     8221 aggctaaaaa atagatagcc tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa
     8281 agacattcaa tttaggatta aagtctattt tcgtttcttt gtaattacga aaagtcttga
     8341 gagatagatg ttgtagccac atgattatct accagggaat cgtggagctt gttggctttt
     8401 aggtgatgaa gcaggtttcg atttgtcttt tttaactccc ttattcatct ttttgacaag
     8461 tttagcgatc cgttcttttt caactttatc agcttggtat tcatcttgtt cttcagaagt
     8521 aggttgtgtc aacaagatgt caatgttcat gtcagggatg tcaactttat cgccaatacg
     8581 aagttttttt ccacgacgac tctctaattc cctattaaag taaacagaat gttcagagag
     8641 aaatgattta atagctcctc cgctatgtgt aattccaagt tctttgagta gtgcttggag
     8701 ggtaataaat tcttcaaata atttgtattc cataattcac ctcaatcttt ggtattatac
     8761 catattttcc taaaaatagt gagagagaca gcgagaaatg taagcgattt ttatttcaaa
     8821 agtgttacag ggaacaagaa aatttcaggt tttcgtgata taatagaagt ctgtatataa
     8881 ggaggtaaat catggagtta gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt
     8941 ttaaaacaaa caaaattacc gtgcgtttta ccgctccatt atcccttgat acgattgcag
     9001 gtcacatgtt gagtgcaagt atgctagaga ctgctaatca gatgtacccc acttctcaag
     9061 atttgaggag acacttggcc agtctatacg gtacagatat gtcaaccaat tgtttcagaa
     9121 gagggcaaag ccacattata gaattgacat ttacctatgt tcgtgatgag tttttaagta
     9181 ggaaaaacgt gctaacttct cagattttgg aacttgtaaa agaaactctt ttttcacccg
     9241 tagtagttga taatgggttt gatccggcct tatttgaaat tgagaaaaaa caattgctag
     9301 caagtttagc agctgatatg gatgattctt tttattttgc acataaagaa ttggataaat
     9361 tgttttttca tgatgaacgt cttcaattgg aatatagtga tttacgaaat cgtattttag
     9421 ctgaaactcc acaaagttct tattcttgtt tccaagaatt tttagccaat gatcgaatag
     9481 atttcttttt cctaggtgat tttaatgagg ttgaaattca aaatgtatta gaatcatttg
     9541 gctttaaagg tcgaaaagga gatgtgaagg ttcagtattg tcaaccttat tctaatatcc
     9601 ttcaggaagg tatggttcgg aaaaatgtgg gacaatctat tttggaatta ggttatcatt
     9661 accgttctaa atatggtgat gagcaacatt tacccatgat tgtaatgaat ggtttacttg
     9721 gtggatttgc tcactctaag ctctttacaa atgtccgtga aaatgctgga ttggcttata
     9781 ctatttcaag tcagcttgat ttatttagtg gatttttgag gatgtatgct ggtattgatc
     9841 gagaaaatcg gaatcaggct cgtaaaatga tgaataatca actgcttgat ttaaaaaaag
     9901 gttattttac agagcttgag ttagagcaga ccaaggaaat gattcgtcgg tctttgttac
     9961 tttctcaaga taatcaaggt tcattgattg aacgtgctta tcaaaatgcc ttacttggaa
    10021 aatcttcagc agactttaaa agttggatta caaaactcga gcaagttgat aaagatgata
    10081 tttgtagagc agctaataat gtgaaactac aagcgattta ctttatggaa ggaatagaat
    10141 gacaaaggtt gtttttgaag aaaaatacta tccagctgta aaagaaatgg tttatcgaac
    10201 tcgtttggcc aacggattga cagttgctct tttgcctaaa aaggaattta aagaggttta
    10261 cgggagtgta actgtacaat ttggttcggt agatacgctt gtcacagaag ttgacggaga
    10321 tgtaaaagaa tatcctgcgg gaattgctca ttttcttgaa cataaattat ttgagagaga
    10381 agattctagt gatttgatgt ctgcttttac gagtctaggt gcagatagta atgcctttac
    10441 aagctttaca aaaacaagtt atcttttttc agcaacggat cattttttag aaaatttaga
    10501 tttacttgat gaattggtaa catcagcaca ctttactgaa gcttccattt tgagagagca
    10561 ggatattatc cagcaagaac gagaaatgta tcaagatgat ccagattcgt gtttattctt
    10621 ttcaacttta gcgaatttgt atcctggtac acctttagca acggatatag ttggaagtga
    10681 ggagtccatt tcccaaatca atctaactaa tttgcaagaa aattttacaa gattttacaa
    10741 acctgtaaac atgtctctgt ttttagttgg tgattttgat gtagagctag ttcagggtta
    10801 ctttgaaaga aaagaactga aagacttaga tgttcaggaa gtagtaagag aaaaatttgt
    10861 tttacaggct gtaaagcaaa cagacagtat gagaatggaa gtatcttctc ccaaactagc
    10921 gattggagtt agaggtaagc gagaagttgc tgaggcggat tgctatcgac atcatgtttt
    10981 attaaaatta ttgtttgcaa tgatgtttgg ttggacttcg gatcgttttc aaaagttata
    11041 tgaatcaggt aaaatagatg cttccttatc tcttgaaatt gaagtaacaa gtcgttttca
    11101 ttttgtcatg ttgacaatgg atacgaaaga gccagttgct ttgtctcatc aatttaggaa
    11161 ggctattcgt aattttacaa aggatttaga tattacagag gaacatttag atattatcaa
    11221 aagagagatg tttggcgaat ttttcagtag catgaactct cttgaattta ttgcaacgca
    11281 atatgatgct tttgaaaatg gtgagacaat ttttgatttg ccgaaaattt tacaggaaat
    11341 tactttagag gatgtccttg atgctggaca tcatttaata gatgatggtg acatagttga
    11401 ttttacaata ttcccatcgt agtaacctat tataatagac actagaaaga agggatgaca
    11461 agtatgagaa aaaaaacaat tggagaggtt ttacgattag ctagaatcaa tcagggattg
    11521 agtttagatg aattgcagaa aaagacagaa atccagttag atatgttgga agcaatggaa
    11581 gcagacgatt tcgatcaact tccaagtcct ttttacacgc gttctttctt gaaaaaatat
    11641 gcatgggctg ttgagttaga tgaccaaatt gttttggatg cttatgattc tgggagtatg
    11701 attacttatg aggaagtaga tgttgatgaa gatgagttga caggtcgtag acgttcaagt
    11761 aagaaaaaga agaaaaaaac atcattttta cctttatttt attttatcct ttttgcttta
    11821 tcgattttaa tttttgtgac ttattatgtt tggaactata ttcaaactca accagaggag
    11881 ccttctcttt ctaattacag tgtggttcaa tcaacaagtt caactagctc tgttccccac
    11941 tcctcaagta gtagttcttc tagtatagaa tcagctataa gtgtatcagg cgaaggaaat
    12001 catgtagaaa tcgcttataa gacaagtaag gaaacagtta aattgcaatt ggcagtttca
    12061 gatgttacaa gttgggtcag tgtttcagaa agcgaacttg agggcggtgt aaccttatcg
    12121 ccaaagaaga aaagtgcaga agcaacagtt gcaactaaag gtcctgtaac aattacgtta
    12181 ggtgttgtaa aaggtgttga tttgacagta gataatcaga ctgttgattt atcgaaatta
    12241 acagctcaga ctggacaaat cactgtaacc tttactaaaa attaaggaaa aacgaatgaa
    12301 aaaagaacaa attcccaatc tcttaacaat aggtcgaatt ctctttatac ctatttttat
    12361 ctttatttta acgataggaa attcgataga gagtcatata gttgcagcta ttatctttgc
    12421 tgttgccagt attaccgact atttagatgg atatttagct cgtaaatgga atgtggtcag
    12481 taattttggt aaatttgcag atcctatggc ggataagtta ctagttatgt cggcttttat
    12541 tatgttgatt gagttaggta tggctccggc ttggattgtt gcagtgatta tctgtcgtga
    12601 gttagctgtg acaggtttaa ggcttttatt ggttgaaact ggtggaacaa ttttagcagc
    12661 agcaatgcct ggaaaaatta aaacttttag tcagatgttt gctattattt tcttgctatt
    12721 acattggact ttgcttggtc aagttctact ttatgtagcc ttatttttca ctatctactc
    12781 tggctatgac tatttcaagg gtagtgccta tgtatttaaa gggacatttg gttcgaaatg
    12841 aaatcaataa ttgatgtaaa aaatctttct tttcgctata aagaaaatca gaactactac
    12901 gatgtgaagg atattacgtt tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat
    12961 aatggtagtg gtaaatcaac gacggttcga ttaattgatg gcttactgga agcagaatcc
    13021 ggagagattg taattgatgg ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt
    13081 caaatcggta tggtttttca aaatccagac aatcaatttg ttggagcgac tgttgaagat
    13141 gatgttgctt ttggtttgga aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg
    13201 gaagaagctc tggatttagt tggcatgttg gactttaaaa agagagagcc agcgcgtcta
    13261 tcaggtggcc aaaagcaacg tgtggccatt gcaggtgttg tagccctaag accagctatt
    13321 ttaatcttag atgaagcaac gagtatgttg gatcctgagg ggcgtagaga acttattggg
    13381 acagtaaaag gaattcgaaa agactatgat atgacggtca tttctattac ccatgatttg
    13441 gaagaagtcg ccatgagtga tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact
    13501 agtagtccaa gggagctttt ctctcgaaat gatttagatc aaattggatt agacgatcct
    13561 tttgctaatc aattaaaaaa atctttgagc cagaatggct atgatttacc tgaaaattat
    13621 ttgacagaaa gtgagctaga ggataagcta tgggaattgc tctagaaaat gtgaatttta
    13681 catatcaaga aggtactccc ttagcttcag cagctttgtc ggatgtttct ttgacgattg
    13741 aagatggctc ttatacagct ttaattgggc acacaggtag tggtaaatca actattttac
    13801 aactcttaaa tggtttattg gtgccaagtc aagggagtgt gagggttttt gataccttaa
    13861 tcacctcgac ttctaaaaat aaagatattc gccaaattag aaaacaggtt ggcttggtat
    13921 ttcagtttgc tgaaaatcag atttttgaag aaacggtttt gaaggacgtt gcttttggac
    13981 cgcaaaattt tggagtttct gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc
    14041 tggttggaat tgatgaatca ctttttgatc gtagtccgtt tgagctgtca gggggacaaa
    14101 tgagacgtgt tgccattgca ggcatacttg ccatggagcc agctatatta gtcttagatg
    14161 agccaacagc tggtctagat cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac
    14221 tccaccagtc agggatgacc atcgtcttgg taacgcattt gatggatgat gttgctgaat
    14281 atgcgaatca agtctatgta atggaaaagg gacgtttagt aaaggggggc aaaccaagtg
    14341 atgtctttca agacgttgtt tttatggaag aagttcagtt gggagtacct aaaattacgg
    14401 ccttttgtaa acgattggct gatagaggcg tgtcatttaa acgattaccg attaagatag
    14461 aggagttcaa ggagtcgcta aatggatagt atgattttag ggcgttatat cccaggggat
    14521 tcgattgttc accgattgga tccacgtagc aaattgcttg ctatgatgct actgattttg
    14581 attgtgtttt gggctaataa ccccttgacg aatctgattc tttttatagc gacagggata
    14641 tttattgcct tgtcaggagt atctctttca ttttttattc agggcttgaa gtctatgttt
    14701 ttcttgattg ccttcacaac tatttttcaa ctatttttca tttctaatgg gaatgtttta
    14761 tttgagtttt cgtttgtgag aatcacggat tatgctttgc aacaagctgg gattattttt
    14821 tgtcgctttg tattgattat tttcttttca actttgttaa ccttaacaac catgccttta
    14881 agtttggcat cagctgtcga agctttatta gcacctttaa agcgtgtgaa agttccagtt
    14941 catgaaattg gattgatgct gtctatgagt ttgcgttttg tcccaacctt gatggatgat
    15001 acgactcgga ttatgaatgc acagaaagct cgtggagtgg attttggaga aggaagtatc
    15061 gttcaaaaag taaaggcgat gattcccatt ttgattcctc tttttgcgac aagtttaaaa
    15121 cgtgcagatt ccttggctat cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga
    15181 agtcaatacc gacaattgaa atggactcta aaggatacgc tgaccattct tgttattctc
    15241 gtacttggtt gttgtttatt tttcttaaaa tcttagtagc tttcaggaat tgataaaaag
    15301 ttactgtaac agtttttgat ataaaggtag ggatatgaac cgttttaaaa aatcaaaata
    15361 tgtcattatt gtttttgtca ctgttctgct tgtgtcagct ctcttagcga cgacttattc
    15421 aagtacaatt gtgacaaaat taggagatgg aatctcattg gttgatagag ttgtacaaaa
    15481 accttttcag tggtttgatt ctgtcaaatc agatttggct catttgacac gaacatataa
    15541 tgaaaatgaa agtttgaaga aacagcttta ccaattagaa gttaaatcaa atgaggtgga
    15601 aagtttaaag acagaaaatg aacaactgcg ccaattgctt gatatgaagt ctaaattgca
    15661 agccacaaag actttagcag cagatgttat tatgcgttct ccggtatctt ggaagcagga
    15721 gttgacctta gatgcaggta gatcaaaagg tgcttctgag aacatgttag ctattgcaaa
    15781 tggtggcttg attgggagta tttcaaaagt agaggagaac tctactatag tcaaccttct
    15841 gacaaatacg gaaaatgctg ataagatttc tgttaaaatt caacatggct ctactacaat
    15901 ttatggaatt attattggct atgacaagga aaatgacgtt cttaaaatta gccaattaaa
    15961 tagtaatagc gatattagtg cgggagataa ggtgactact ggtggattag gaaactttaa
    16021 cgttgctgat attcctgttg gtgaagtggt tgccacaacg catagtacag actatttgac
    16081 acgagaagta actgttaaat tgagtgcaga tactcataat gtagatgtga tagaattagt
    16141 ggggaattca taatgagaca gttgaagcga gttggagtat ttttattgct tcctttcttt
    16201 gttctaattg acgcccatat tagccagctt ctgggctcat ttttccccca tgtacatttg
    16261 gctagtcatt ttctttttct atttctctta tttgagacga tagaagtatc agagtatctc
    16321 tacctagtct attgttttgt tataggcttg gtttatgatg tttacttttt ccatctaata
    16381 gggattacaa ctctcttatt tatcttattg ggagccttcc ttcataaatt gaatagtgtt
    16441 attttgttga atcgttggac aagaatgcta gctatgattg tgctgacatt cctgtttgaa
    16501 atgggtagtt atcttttggc ttttatggta gggttgacag tagatagcat gtcgattttt
    16561 atagtctata gcttggtacc gacgatgatt ttaaattttt tatggattac tgtttttcaa
    16621 tttatttttg aaaaatatta tctataagaa cgacatataa atgtaacaaa ggcgtaatat
    16681 ttattaggcc tttttttggt atactagtat tgtctttaaa agaaggagta tctacgtaat
    16741 atgaagaaaa aaatcttagc gtcactttta ttaagtacag taatggtttc tcaagtagct
    16801 gttttaacaa ctgcgcatgc agaaacgact gatgacaaaa ttgctgctca agataataaa
    16861 attagtaact taacagcaca acaacaagaa gcccaaaaac aagttgacca aattcaggag
    16921 caagtatcag ctattcaagc tgagcagtct aacttgcaag ctgaaaatga tagattacaa
    16981 gcagaatcta agaaactcga gggtgagatt acagaacttt ctaaaaacat tgtttctcgt
    17041 aaccaatcgt tggaaaaaca agctcgtagt gctcaaacaa atggagccgt aactagctat
    17101 atcaatacca ttgtaaactc aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg
    17161 agtgaaatcg tatctgcaaa caacaaaatg ttagaacaac aaaaggcaga taaaaaagct
    17221 atttctgaaa aacaagtagc aaataatgat gctatcaata ctgtaattgc taatcaacaa
    17281 aaattggctg atgatgctca agcattgact acgaaacagg cagaactaaa agctgctgaa
    17341 ttaagtcttg ctgctgagaa agcgacagct gaaggggaaa aagcaagtct attagagcaa
    17401 aaagcagcag ctgaggcaga ggctcgtgca gctgcggtag cagaagcagc ttataaagaa
    17461 aaacgagcta gccaacaaca atcagtactt gcttcagcaa acactaactt aacagctcaa
    17521 gtgcaagcag tatctgaatc tgcagcagca cctgtccgtg caaaagttcg tccaacatac
    17581 agtacaaacg cttcaagtta tccaattgga gaatgtacat ggggagtaaa aacattggca
    17641 ccttgggctg gagactactg gggtaatgga gcacagtggg ctacaagtgc agcagcagca
    17701 ggtttccgta caggttcaac acctcaagtt ggagcaattg catgttggaa tgatggtgga
    17761 tatggtcacg tagcggttgt tacagctgtt gaatcaacaa cacgtatcca agtatcagaa
    17821 tcaaattatg caggtaatcg tacaattgga aatcaccgtg gatggttcaa tccaacaaca
    17881 acttctgaag gttttgttac atatatttat gcagattaat ttacagaggg actcgaatag
    17941 agccctcttt tcaggtttta ccgtgacaat ccctattaaa aattatatca aaatagcttg
    18001 aaaatattgg aaaagtatgg tagaatgaaa attgtcgtgt gaacgataat actcattctt
    18061 gatgaattgt gaagcagttg cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa
    18121 aaaacaaaaa ggagaaatac tcatggcagt aatttcaatg aaacaacttc ttgaggctgg
    18181 tgtacacttt ggtcaccaaa ctcgtcgctg gaatcctaag atggctaagt acatctttac
    18241 tgaacgtaac ggaatccacg ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc
    18301 atacgacttc atgcgtgatg cagcagctaa cgatgcagtt gtattgttcg ttggtactaa
    18361 gaaacaagca gctgatgcag ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa
    18421 ccaccgttgg ttgggtggaa ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg
    18481 tttgaaagaa attaaacgta tggaagaaga tggaactttc gaagttcttc ctaagaaaga
    18541 agttgcactt cttaacaaac aacgtgcgcg tcttgaaaaa ttcttgggtg gtatcgaaga
    18601 tatgcctcgt atcccagatg tgatgtacgt agttgaccca cataaagagc aaatcgctgt
    18661 taaagaagct aaaaaattgg gaatcccagt tgtagcgatg gttgacacca atactgatcc
    18721 agatgatatc gatgtaatca tcccagctaa cgatgacgct atccgtgctg ttaaattgat
    18781 cacagctaaa ttggctgacg ctattatcga aggacgtcaa ggtgaggatg cagtagcagt
    18841 tgaagcagaa tttgcagctt cagaaactca agcagattca attgaagaaa tcgttgaagt
    18901 tgtagaaggt gacaactctt aatttataca aatagtaatt acctaggagg gcggggctta
    18961 gcccggctct cctattttca aaaaatatag gagaattaaa atggcagaaa ttacagctaa
    19021 acttgtaaaa gagttgcgtg aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct
    19081 tgtagaaaca gacggtgaca tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc
    19141 taaggcagct aagaaagctg accgtgttgc tgcagaaggt ttgactggtg tttatgttaa
    19201 cggtaatgtt gcagcagtta ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc
    19261 tcaattcgtt gaattggtaa atactacagc taaagtcatt gctgaaggaa aacctgctaa
    19321 caatgaagaa gctcttgctt tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt
    19381 atctgcaaca gcaactatcg gagagaaaat ctcattccgt cgctttgcat tgattgaaaa
    19441 aacagacgca caacactttg gagcatacca acataacggt ggacgtatcg gtgttatttc
    19501 agttgttgaa ggtggagacg aagcacttgc taaacaattg tcaatgcaca tcgcagcgat
    19561 gaaaccaaca gttctttctt acaaagaatt ggatgagcaa ttcgttaaag atgagttggc
    19621 acaattgaat cacgttatcg accaagacaa cgaaagccgt gcaatggtta ataaaccagc
    19681 tcttccacac ttgaagtatg gatcaaaagc tcaattaact gatgatgtta ttgctcaagc
    19741 tgaagctgac atcaaagctg aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa
    19801 aattattcca ggtaaaatgg atcgcttcat gcttgataac actaaagttg accaagctta
    19861 cacacttctt gcacaagttt acatcatgga tgacagcaag acagttgaag cataccttga
    19921 atcagttaac gcttcggtag ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa
    19981 agctgcaaac gacttcgaag ctgaagttgc agctacaatg gcagcagcct tgaataacta
    20041 ataatagaaa ggaagcaatt tgcttccttt tttgtatagg gcttatattt ttcctgaaat
    20101 tgtttttccc ccagtctcac tcgattagaa taattaaaac aaaaagccct ataataaggg
    20161 ctaagtgcat ttaggagact atacttcaaa ttcatagtaa gcgcgtcata acaaggtatc
    20221 tatcctaatt ccccaacttc cagtatacta gataaaaaat aattatcgga ggaaaggtat
    20281 tgtactatga tgattcaact aagtgattta ggtcaagttc acattgtttg tggcaagaca
    20341 gatatgaggc agggaataga ctcattagcc tatgtagtta aaacccactt tgaattggat
    20401 tctttctccg gtcaagtctt tctcttttgt ggtggacgta aagaccgctt taaagtcctt
    20461 tactgggatg gtcaaggatt ttggctacta tataaacgct ttgagaacgg aaaactgact
    20521 tggctaagta cagaaaagga tgtcaaagct ctcacatctg aacaagtaga ctggcttatg
    20581 aagggctttt ctatcactcc ccaaatatag tggtttgaaa ctagaatagt acacctctgc
    20641 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgttc ttatttcatt ttactataaa
    20701 ttcatcagaa agtcgtgatt tctattgaaa tgaggacttt ctttttatac tcatctgttt
    20761 tcacaaagca ttctagtcca tctccgatta acgatggact ttatcacctc cttctccagt
    20821 ccttgtataa catcttggag ttgattcatg acatcttcca aaatttgaaa ggctttattc
    20881 ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat ctctggtgtg
    20941 tatggaggaa taaatgcaaa gccaatatta gtcggaatct ttaaggtact tgatttatgc
    21001 catatagcat tgtccataac gagtaaaaga taatcatctg gataagcttg tgaaatctcc
    21061 tattcctaaa gcccctttag cgcataactt tggctcagct tctattatcg ctcacaccat
    21121 ccatcagaag tttaatctga aggtacccaa ttatcgccaa gaagaagatt gggctaggat
    21181 gggtttacca atcacacgta aggaaatctc taatcggcat atcaagacga gtcaatacta
    21241 tttggagccc ctttataacc tcttgcgaga gagactattg actcagccct tacttcatgc
    21301 ggatgaaact tcttataggg tgctagagag tgatagtcag ctgacttact attggacttt
    21361 tttgtctggg aaagctgaga aacaagggat tacgctttac catcatgtcc taatcgattt
    21421 gttcatatct tatttcaatc cattataaat agtgagaaat atctatccta tcttctagaa
    21481 tgtcttccaa acgtggaaac tctcgtaaac aaagaggttt tagaggccta tttaccatgg
    21541 actaaagttg tacaagaaaa gtgcaaataa gaaatctcca gattaggaac tatccgtgag
    21601 ttctctagtc tggagatttt tcaatagact tcgttattgg acggttacaa ttcataaagt
    21661 gctgtagaga gataacgttc accgttatct ggtgctaggg caaggacttt tttacctgta
    21721 cctaattttt tggcaacctc gatggctccg tagatagctg cagctgagga aatccctaca
    21781 aggaagcctt cttttccacc aatttcacgt ccgagtgcaa gagcgtcatc tgatgttaca
    21841 cgaacgatac catcataggc tttagtatca agtgtatcag gaataaatcc agctgagata
    21901 ccttgaattt tgtgaggacc aggtttttca ccagatagaa tagcagattc atctgcttct
    21961 actgcaaaaa cttgaatgtt agaattttct gatttgagtg catgagaaac accagaaatc
    22021 gttccaccag tacctactcc agcaacaaag gcatctaatc catctttacc gaaagcagct
    22081 agtatctcag ctcctgttgt tctttcgtgt acttctggat tagctggatt gtcaaattga
    22141 agaggaagga aaccatcacg ttcagcagcg atttcttgag ccttagcaat agcacctttc
    22201 attccctcgc taccaggagt taggacgagt tcagcaccat aagcttggat aattttacgt
    22261 cgttctacac tcatagtttc aggcataacg atgacgactt tatacccttt agcagcacct
    22321 acccatgaaa gtccaatacc ggtgtttcca cttgttgctt caacaatagt agaaccaagt
    22381 ttcagaatac catcttgttc agctttttca atcatgctaa gggcaatacg gtcttttaca
    22441 gatgaaccag gattaaatgc ttcaagcttt atatagacgt ctgcagcacc ttctggcacg
    22501 atgttgttaa gtttaacaat cggtgtttga ccgattaatt cagtaatgtt gttataaata
    22561 gacatatgaa tacctctttg tataagatat ctttagtata acgctatcca taccatttgt
    22621 aaaatataga aatcctatcg aagcgatagg atttctatat atcatagatc aaagtcatta
    22681 attttcaagt gattgcgttc agttaattct agtaaatagg tgtgaaggaa aacgatatca
    22741 ggtttcgttt gaattgcttc attttctagt atattttggt acgcatcttt ttattttgct
    22801 cgctaaagta gttgtgagaa tgtcaacgaa acgctgtatt attcattgtt tacactaagt
    22861 ttacaggaac ttcaacctct cgtaaacctt ggtcagttaa agtgactttt ccattaaaaa
    22921 actccacaag tgcagcttta atagtttctt tttcttcttt atcaacataa atcatcgtat
    22981 cgacttgatc tgtaaagttt gtatccagct ccatgagatc atgttcttta aggaagttac
    23041 tgtactcttg gtactgagca taagacattt gaatagcaat gccagcctgt tcttttattt
    23101 caataatacc aatttctttg acagctaagg cgacactgct ggcgtaagca cgaattagtc
    23161 ctccagcgcc tagtttaata ccaccaaagt agcgtgtcac gaccacacag acattggtga
    23221 gattgtgatt ttctagtacc ccaagcatgg gaacaccagc agtaccacta ggctcaccat
    23281 catcacttgt acgtttaatt tcactacgtt ctccaataat aaaggcagag cagttatgtg
    23341 tcgctttgta gtgttctttt ttgatggcag taatgaagtc acgagcctct tcttcgctat
    23401 aaacacgctt ggcatggcag ataaagcgag attttttgat ttcttcttgg acttggccgt
    23461 cctctttaat tgtcctaaat tccatgattt aattgtacta aaaaatcatc taaagtgcta
    23521 gtttttacga ataaagaagt atgaaagtaa atttagatta tctcggtcgt ttatttactg
    23581 agaatgaatt aacagaagaa gaacgtcagt tggcggagaa acttccagca atgagaaagg
    23641 agaaggggaa acttttctgt caacgttgta atagtactat tctagaagaa tggtatttgc
    23701 ccatcggtgc ttactattgt cgagagtgct tgctgatgaa gcgagtcaga agtgatcaaa
    23761 ctttatacta ttttccgcag gaggattttc cgaagcaaga tgttctcaaa tggcgcggcc
    23821 aattaactcc ttttcaagag aaggtgtcag agggactgct tcaagcagta gacaagcaaa
    23881 agccaacctt agttcatgcg gtaacaggag ctggaaagac agaaatgatt tatcaagtag
    23941 tggctaaagt gatcaatgcg ggtggtgcag tgtgtttggc tagtcctcgc atagatgttt
    24001 gtttggagct gtacaagcgc ctgcaacagg atttttcttg cgggatagct ttgctacatg
    24061 gagaatcgga accttatttt cgaacaccac tagttgttgc aacaacccat cagttattga
    24121 agttttatca agcttttgat ttgctgatag tggatgaagt agatgctttt ccttatgttg
    24181 ataatcccac gctttaccat gctgtcaaga atagtgtaaa ggagaatgga ttgagaatct
    24241 ttttaacagc gacttcgacc aatgagttag ataaaaaggt ccgtttagga gaactaaaaa
    24301 gactgaattt accgagacgg tttcatggaa atccgttgat tattccaaaa ccaatttggt
    24361 tatcggattt taatcgctac ttagacaaga atcgtttgtc accaaagtta aagtcctata
    24421 ttgagaagca gagaaagaca gcttatccgt tactcatttt tgcttcagaa attaagaaag
    24481 gggagcagtt agaagaaatc ttacaggagc aatttccaaa tgagaaaatt ggctttgtat
    24541 cttctgtaac agaggatcga ttagagcaag tacaagcttt tcgagatgga gaactgacaa
    24601 tacttatcag tacgacaatc ttggagcgtg gagttacctt cccttgtgtg gatgttttcg
    24661 tagtagaagc caatcatcgt ttgtttacca agtctagttt gattcagatt ggtggacgag
    24721 ttggacgaag catggataga ccgacaggag atttgctttt cttccatgat gggttaaatg
    24781 cttcaatcaa gaaggcgatt aaggaaattc agatgatgaa taaggaggct ggtctatgaa
    24841 gtgcttgtta tgtgggcaga ctatgaagac tgttttaact tttagtagtc tcttacttct
    24901 gaggaatgat gactcttgtc tttgttcaga ctgtgattct acttttgaaa gaattgggga
    24961 agagaactgt ccaaattgta tgaaaacaga gttgtcaaca aagtgtcaag attgtcaatt
    25021 ttggtgtaaa gaaggagttg gagtcagtca tagagcgatt tttacttaca atcaagctat
    25081 gaaggatttt ttcagtcggt ataagtttga tggagacttc ctgttaagaa aagttttcgc
    25141 ttcattttta agtgaggagt tgaaaaagta caaagagtat caatttgttg taattcccct
    25201 aagtcctgat agatatgcta atagaggatt taatcaggtt gagggcttgg tagaggcagc
    25261 aggctttgag tatctggatt tattagagaa aagagaagag agagccagtt cttctaaaaa
    25321 tcgttcagag cgcttgggga cagaacttcc tttctttatt aaaagtggag tcactattcc
    25381 taaaaaaatc ctacttatag atgatatcta tactacagga gcaactataa atcgtgttaa
    25441 gaaactgttg gaagaagctg gtgctaagga tgtaaaaaca ttttcccttg taagatgagg
    25501 aaaaaatttg caaaaataga atgaaagcgt tataataaaa tcataaaaac aaaaatgttt
    25561 agaaagaagg tactcatatg attaaatata gtatccgtgg tgaaaaccta gaagtaacag
    25621 aagcaattcg tgattatgta gtttctaaac tcgaaaagat cgaaaagtac ttccaaccag
    25681 aacaagagtt ggatgcccga attaacttaa aagtttatcg tgaaaaaacg gctaaagtgg
    25741 aagtaacgat tccgcttgga tctattactc tccgcgcaga agatgtatct caagatatgt
    25801 atggttcaat tgaccttgta actgataaaa ttgaacgtca gattcgtaaa aataaaacaa
    25861 aaatcgagcg taaaaataaa aataaggtag caactggtca attatttaca gatgctttgg
    25921 tggaagattc aaatgttgtc cagtctaaag ttgttcgttc aaaacaaatt gatttaaaac
    25981 caatggattt ggaagaagca attctacaaa tggatttatt ggggcatgat ttctttatct
    26041 atgtggatgt tgaagatcag acaaccaatg tgatttatcg tcgtgaggat ggcgaaattg
    26101 gtttgttaga ggttaaagaa tcttaatttc aatatgtgta aaggtaggtt tactgaattg
    26161 taaactacct ttttcttata attgatagaa ttactgatta cacttttaaa aagtcgcttt
    26221 ttgaggggta ttatggtata atgggtgcca agaggttttg aatgaaaaaa ttttatgtaa
    26281 gtccaatttt tcctattcta gtaggattga ttgcgtttgg agtcttatcc actttcatta
    26341 tttttgttaa taataatctg ttgacggttt taattttgtt tctttttgta ggaggctatg
    26401 tttttttatt taagaaactg agagtgcatt atacaaggag tgatgtagaa cagatacagt
    26461 atgtaaacca ccaagcggaa gaaagtttga catctctatt ggaacaaatg cctgtaggtg
    26521 ttatgaaatt gaatttatct tctggagagg ttgagtggtt taatccctat gctgaattga
    26581 ttttgaccaa ggaagatggt gattttgatt tagaagctgt tcaaacgatt atcaaggctt
    26641 cagtaggaaa tccgtctact tatgccaagc ttggtgagaa gcgttatgct gttcatatgg
    26701 atgcttcttc cggtgttttg tattttgtag atgtatccag ggaacaagcc ataacagatg
    26761 aattggtaac aagtcgacca gtgattggga ttgtctctgt ggataattat gatgatttgg
    26821 aggatgcaac ttctgagtca gatattagtc aaatcaatag ttttgtagct aattttatat
    26881 cagagttttc agaaaaatac atgatgtttt ctcgtcgggt aagtatggat cgattttatc
    26941 tatttactga ctacacggtg cttgagggct tgatgaatga taaattttct gttattgatg
    27001 ctttcagaga agagtcgaaa cagagacagt tgcccttgac cttaagtatg ggattttctt
    27061 atggcgatgg aaatcatgat gagataggga aagttgcttt gctcaatttg aacttggctg
    27121 aagtacgtgg tggcgaccag gtggttgtta aggaaaacga cgaaacgaaa aatccagttt
    27181 attttggtgg tgggtctgct gcttcaatca agcgtacacg gactcgtacg cgcgctatga
    27241 tgacagctat ttcagataag attcggagtg tagatcatgt ttttgtagtc ggtcacaaaa
    27301 atttagacat ggatgctttg ggctctgctg taggtatgca gttgttcgcc agcaatgtga
    27361 ttgaaaatag ctatgctctt tatgatgaag aacaaatgtc tccagatatt gaacgagctg
    27421 tttcattcat agaaaaagaa ggagttacga agttgttgtc tgttaaggat gcaatgggga
    27481 tggtgaccaa tcgttctttg ttgattcttg tagaccattc aaagacagcc ttaacattat
    27541 caaaagaatt ttatgattta tttacccaaa ccattgttat tgaccaccat agaagggatc
    27601 aggattttcc agataatgcg gttattactt atatcgaaag tggtgcaagt agtgccagtg
    27661 agttggtaac ggaattgatt cagttccaga attctaagaa aaatcgtttg agtcgtatgc
    27721 aagcaagtgt cttgatggct ggtatgatgt tggatactaa aaatttcacc tcgcgagtaa
    27781 ctagtcggac atttgatgtt gctagctatc tcagaacgcg cggaagtgat agtattgcta
    27841 tccaggaaat cgctgcgaca gattttgaag aatatcgtga ggtcaatgaa cttattttac
    27901 aggggcgtaa attaggttca gatgtactaa tagcagaggc taaggacacg aaatgctatg
    27961 atacagttgt tattagtaag gcagcagatg ccatgttagc catgtcaggt attgaagcga
    28021 gttttgttct tgcgaagaat acacaaggat ttatctctat ctcagctcga agtcgtagta
    28081 aactgaatgt acaacggatt atggaagagt taggcggtgg aggccacttt aatttggcag
    28141 cagctcaaat taaagatgta accttgtcag aagcaggtga aaaactgaca gaaattgtat
    28201 taaatgaaat aaaggaaaag gagaaagaag aatgaaagta atctttttag cagatgttaa
    28261 aggaaaaggt aaaaaaggcg aaattaagga agtaccaaca gggtatgcgc aaaactttct
    28321 tatcaaaaag aatctagcca aagaagcgac tgctcaagct gtaggtgaac ttcgtggtaa
    28381 acaaaaatcg gaagaaaaag ctcacgctga gatgattgca gaaggaaaag caattaaagc
    28441 acaacttgaa gcagaagaaa ctgttgtaga atttgttgaa aaagttggtc cagatggtcg
    28501 tacctttggt tctattacca ataagaagat tgcagaagaa ttgcaaaagc aatttggaat
    28561 taagattgat aaacgtcata ttcaagtaca agctccgatt cgagcggttg gtttgattga
    28621 tgtgccagtg aaaatctatc aagatatcac aagtgtaatc aatcttcgtg tgaaagaagg
    28681 ataagtttac accttcttga caagattgta aaaggaagag aagtctgatg gcagaagtag
    28741 aagagttacg agtacaacct caagatatct tagctgagca atccgtttta ggggctatct
    28801 ttattgatga gagtaaactt gtttttgtgc gagaatacat tgagtctcgg gactttttta
    28861 agtatgccca tcgtttgatt ttccaagcca tggtcgattt atccgatcgt ggtgatgcca
    28921 tagatgcaac aacggttcgt actatccttg ataatcaagg tgatttacag aatattggtg
    28981 gcttgtctta cttggttgag attgtcaatt ctgtgccaac ttctgctaat gcggagtatt
    29041 atgctaagat tgttgcagaa aaagcaatgc tacgtcgttt aattgccaag ttgacagagt
    29101 ctgtcaacca agcttacgaa gcgtcacaac cagctgatga aattattgct caggcagaaa
    29161 aagggctgat tgatgtcagt gaaaatgcaa atcgaagcgg gtttaagaac attcgagatg
    29221 tgttgaatct caactttgga aatctggaag ctcgctcgca acaaacgacc gatattacag
    29281 gtattgcgac aggttatcgt gatttggatc atatgacaac aggacttcat gaggaggagt
    29341 tgattatctt agcagctcgt ccagcagttg gtaagacagc atttgccttg aatatcgctc
    29401 agaatattgg gactaagttg gacaaaacgg ttgctatttt ttcactcgaa atgggtgcgg
    29461 aaagcttggt agaccgtatg ttagctgcag aaggcttggt ggagtcacat tctatccgta
    29521 cagggcaatt gacagatgag gagtggcaaa aatatactat tgctcagggt aatctagcta
    29581 acgccagtat ctatatcgat gatacgccag gtattcggat tacagagatt cgttctcgtt
    29641 ctcgtaaatt ggctcaagaa actggaaatc ttggtttgat tttgatagac tatttgcaac
    29701 ttatcacggg aactggtcga gaaaatcgtc aacaagaagt ttctgaaatt tctcgtcagt
    29761 tgaaaatact agccaaggaa ttgaaggttc cagtaatcgc tctgagtcag ctttctcgtg
    29821 gtgtagaaca acgtcaggac aagagaccgg tcttgtctga tattcgtgaa tctgggtcta
    29881 ttgagcagga cgctgatatc gtagcttttc tctatcgcga tgactactat gaacgtggtg
    29941 gtgaagaaga ggagggtatc ccaaataata aggtggaagt tattatcgag aaaaaccgta
    30001 gtggagctcg tggaacagtg gaattgattt tccaaaaaga atacaataaa ttttcaagta
    30061 tctcaaagag ggaggcataa gatgtcagat gcatttacag atgtagccaa gatgaaaaaa
    30121 atcaaagaag aaattaaggc acatgaggga caagtcgtag aaatgacttt ggagaatggt
    30181 cgtaagcgcc aaaaaaatag attgggtaag ctaattgaag tttatccatc cctatttatt
    30241 gtggagtttg gggatgtgga aggagataaa caagttaatg tttacgttga atcctttact
    30301 tactcagata ttcttacaga aaagaatttg attcattatc ttgactaaag tgagaaattt
    30361 tctcactttt tcttttttct ccgaataatt taggtgaagg caatcatcgc tttatattat
    30421 tttttaagga ggaagaatga aaattttacc gtttatagca agaggaacaa gttattactt
    30481 gaagatgtca gttaaaaagc ttgttccttt tttagtagta ggattgatgc tagcagctgg
    30541 tgatagtgtc tatgcctatt ccagaggaaa tggatcgatt gcgcgtgggg atgattatcc
    30601 tgcttattat aaaaatggga gccaggagat tgatcagtgg cgcatgtatt ctcgtcaatg
    30661 tacttctttt gtagcctttc gtttgagtaa tgtcaatggt tttgaaattc cggcagctta
    30721 tggaaatgcg aatgaatggg gacatcgtgc tcgtcgggaa ggttatcgtg tagataatac
    30781 accgacgatt ggttccatta cttggtctac tgcaggaact tatggtcatg ttgcctgggt
    30841 gtcaaatgta atgggagatc agattgagat tgaggaatat aactatggtt atacagaatc
    30901 ctataataaa cgaattataa aagcaaacac gatgacagga tttattcatt ttaaagattt
    30961 ggatggtggc agtgttggga atagtcaatc ctcaacttca acaggcggaa ctcattattt
    31021 taagaccaag tctgctatta aaactgaacc cctagttagt gcaactgtga ttgattacta
    31081 ttatcctgga gagaaggttc attatgatca aattctcgaa aaagacggct acaagtggtt
    31141 gagttatact gcctataatg gaagctatcg ttatgttcaa ttggaggctg tgaataaaaa
    31201 tcctctaggt aattctgttc tttcttcaac aggtggaact cattatttta agaccaagtc
    31261 tgctatcaaa actgaacccc tagttagtgc aactgtgatt gattactatt atcctgggga
    31321 gaaggttcat tatgatcaga tacttgaaaa agacggctac aagtggttga gttatacggc
    31381 ttataacgga agtcgtcgct atatacagct agagggagtg acttcttcac aaaattatca
    31441 gaatcaatca ggaaatatct ctagctatgg atccaataat agttcaactg tcggttggaa
    31501 gaaaataaat ggtagttggt atcatttcaa atcaaatggt tctaaatcaa caggatggct
    31561 gaaagacggt tctagctggt attatttgaa attatctggt gaaatgcaga caggatggtt
    31621 aaaggagaat ggctcgtggt attatctggg tagttcaggg gcaatgaaaa caggctggta
    31681 ccaggtctct ggtaagtggt attattctta ctcttcaggc gccttagctg ttaatacgac
    31741 ggtggatggc tacagagtaa acagtgatgg agaacgagta tagaaaattg gagtaggaga
    31801 aatttcctgc tcttttctgt aagcagtttc cttgacattt ttcttatttt gcgctatcat
    31861 atatacatat aatatatggg agtctgtgta cagtctgaga ggaagtgtta aacttcgacc
    31921 gcacctgatc tgggtaatgc cagcggaggg aacgatactt agtctaattt tgcacctttt
    31981 ccatgtatgg taaaggtttt tctttttttt aaaaggaaaa cgagaagagg aggttcttat
    32041 gaaagcaagc attgccttgc aagttttacc cctagcacag gggattgatc ggatagctgt
    32101 tattgatcag gtcattgctt atctgcaaac tcaagaagtg acgatggtag tgacaccatt
    32161 tgaaacggtc ttggaagggg agtttgatga gcttatgcgc attctaaaag aagcgctgga
    32221 agtggcaggg caggaggcag acaatgtctt tgccaatgtc aaaataaatg taggagagat
    32281 tttaagtatt gatgagaaac ttgaaaagta tactgagacg acacattagt ctattgggct
    32341 ttctcggagt cttgtcaatc tggcagttag caggttttct taaacttctc cccaagttta
    32401 tcctgccgac acctcttgaa attctccagc cctttgttcg tgacagagaa tttctctggc
    32461 accatagctg ggcgaccttg agagtggctt tactggggct gattttggga gttttgattg
    32521 cctgtcttat ggctgtgctc atggatagtt tgacttggct caatgacctg atttacccta
    32581 tgatggtggt cattcagacc attccgacca ttgccatagc tcctatcctg gtcttgtggc
    32641 taggttatgg gattttgccc aagattgtct tgattatctt aacgacaacc tttcccatca
    32701 tcgttagtat tttggacggt tttaggcatt gcgacaagga tatgctgacc ttgtttagtc
    32761 tgatgcgggc caagccttgg caaatcctgt ggcattttaa aatcccagtt agcctgcctt
    32821 acttttatgc aggtctgagg gtcagtgtct cctacgcctt tatcacaact gtggtatctg
    32881 agtggttggg aggttttgaa ggtcttggtg tttatatgat tcagtctaaa aaactgtttc
    32941 agtatgatac catgtttgcc attattattc tggtgtcgat tatcagtctt ttgggtatga
    33001 agctggtcga tatcagtgaa aaatatgtga ttaaatggaa acgttcgtag aattagaatg
    33061 tttctgaaaa agaaaagagg aaatcaaaat gaagaaaaca tggaaagtgt ttttaactgt
    33121 tttaacagct cttgtagctg tcgtgcttgt agcttgtggt caaggaactg cttctaagga
    33181 caacaaagaa gcagaactca agaagatcga ctttatccta gactggacac caaacactaa
    33241 ccacacaggg ctatatgttg ccaaggaaaa aggttatttc aaagaagctg gagtggatgt
    33301 tgatttgaaa ttgccaccag aagaaagttc ttctgacttg gttatcaacg gaaaggcacc
    33361 atttgcagta tatttccaag actacatggc taagaaattg gaaaaaggag caggaatcac
    33421 tgccgttgca gctattgttg aacacaatac atcaggaatc atctctcgta aatctgataa
    33481 tgtaagcagt ccaaaagact tggttggtaa aaaatatggg acatggaatg acccaactga
    33541 acttgctatg ttgaaaacct tggtagaatc tcaaggtgga gactttgaga aggttgaaaa
    33601 agtaccaaat aacgactcaa actcaatcac accgattgcc aatggcgtct ttgatactgc
    33661 ttggatttac tacggttggg atggtatcct tgctaaatct caaggtgtag atgctaactt
    33721 catgtacttg aaagactatg tcaaggagtt tgactactat tcaccagtta tcatcgcaaa
    33781 caacgactat ctgaaagata acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa
    33841 aggctaccaa tatgccatgg aacatccaga agaagctgca gatattctca tcaagaatgc
    33901 acctgaactc aaggaaaaac gtgactttgt catcgaatct caaaaatact tgtcaaaaga
    33961 atacgcaagc gacaaggaaa aatggggtca atttgacgca gctcgctgga atgctttcta
    34021 caaatgggat aaagaaaatg gtatccttaa agaagacttg acagacaaag gcttcaccaa
    34081 cgaatttgtg aaataatgac agaaattaga ctagagcacg tcagttatgc ctatggtcag
    34141 gagaggattt tagaggatat caacctacag gtgacttcag gcgaagtggt ttccatccta
    34201 ggcccaagtg gtgttggaaa gaccaccctc tttaatctaa tcgctgggat tttagaagtt
    34261 cagtcaggga gaattgtcct tgatggtgaa gaaaatccca aggggcgcgt gagttatatg
    34321 ttgcaaaagg atctgctctt ggagcacaag acggtgcttg gaaatatcat tctgcccctc
    34381 ttgattcaaa aggtggataa ggcagaagct atttcccgag cggataaaat tcttgcgacc
    34441 ttccagctga cagctgtaag agacaagtat cctcatgaac ttagcggtgg gatgcgccag
    34501 cgtgtagcct tactccggac ctaccttttt gggcacaagc tctttctctt agatgaggcc
    34561 tttagcgcct tggatgagat gacaaagatg gaactccacg cttggtatct tgagattcac
    34621 aaacagttgc agctaacaac tctgatcatc acgcatagta ttgaggaggc cctcaatctc
    34681 agcgaccgca tctatatctt gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta
    34741 gattggtctg aagatgagga caaggaagtc caaaagattg cctacaaacg tcaaatcttg
    34801 gcagaattag gcttagataa gtagaaaaat agggagttgg tgaagattat cctttaccag
    34861 cgcccttttt cttttaaaaa tgagaaaatt tcggtataat agtcaaacaa ggtcaaggtt
    34921 taaagagaga ggtgggtttg ttatgagatt taaaaataca tcggatcata ttgaggccta
    34981 catcaaggcg attttagatc aatctggtat cgtggagttg caacggagtc agttggcaga
    35041 tacctttcag gttgttccta gtcagattaa ctacgtgatc aagacacgct ttacggaaag
    35101 tagaggctac ttggttgaaa gtaagcgtgg tggcggaggc tacattcgta taggacggat
    35161 tgagttttct agtcatcatg aaatgctccg ggatctgctt tactcgattg gtgagcgagt
    35221 cagtcaagaa atttatgagg atattctcca gcttttggtt gagcaggaat tgatgaccaa
    35281 gcaggagata aatttgctag aatcagtagc tttggatcgc gttttaggag aagaagctcc
    35341 agttgttcga gcaaacatgc tacgtcaggt catacaagag gtagatagaa aagggaagta
    35401 agatgaacta ttcaaaagca ttgaatgaat gtatcgaaag tgcctacatg gttgctggac
    35461 attttggagc tcgttatcta gagtcgtggc acttgttgat tgccatgtct aatcacagtt
    35521 atagtgtagc aggggcaact ttaaatgatt atccgtatga gatggaccgt ttagaagagg
    35581 tggctttgga actgactgaa acggactata gccaggatga aacctttacg gaattgccgt
    35641 tctcccgtcg tttgcaggtt ctttttgatg aagcagagta tgtagcgtca gtggtccatg
    35701 ctaaggtact agggacagag cacgtcctct atgcgatttt gcatgatggc aatgccttgg
    35761 cgactcgtat cttggagagg gctggttttt cttatgaaga caagaaagat caggtcaaga
    35821 ttgctgctct tcgtcgaaat ttagaagaac gggcaggctg gactcgtgaa gatctcaagg
    35881 ctttacgcca acgccatcgt acagtagctg acaagcaaaa ttctatggcc aatatgatgg
    35941 gcatgccgca gactcctagt ggtggtctcg aggactatac gcatgatttg acagagcaag
    36001 cgcgttctgg caagttagaa ccagtcatcg gtcgggacaa ggaaatctca cgtatgattc
    36061 aaatcttgag ccgtaagact aagaacaacc ctgtcttggt tggggatgct ggtgtcggga
    36121 aaacagctct ggcgcttggt cttgctcagc gtattgctag tggtgacgtg cctgcggaaa
    36181 tggctaagat gcgcgtgtta gaacttgatt tgatgaatgt cgttgcaggg acacgcttcc
    36241 gtggtgactt tgaagaacgc atgaataata tcatcaagga tattgaagaa gatggccaag
    36301 tcatcctctt tatcgatgaa cttcacacca tcatgggttc tggtagcgga attgattcga
    36361 ctctggatgc ggccaatatc ttgaaaccag ccttggcgcg tggaactttg agaacggttg
    36421 gtgccaccac tcaggaagaa tatcaaaaac atatcgaaaa agatgcagca ctttctcgtc
    36481 gtttcgctaa agtgacgatt gaagaaccaa gtgtggcaga tagtatgact attttacaag
    36541 gtttgaaggc gacttatgag aaacatcacc gtgtacaaat cacagatgaa gcggttgaaa
    36601 cagcggttaa gatggctcat cgttatttaa ccagtcgtca cttgccagac tctgctatcg
    36661 atctcttgga tgaggcggca gcaacagtgc aaaataaatc aaagcatgta aaagcagacg
    36721 attctgactt gagtccagct gacaaggcct tgatggatgg caagtggaaa caggcagccc
    36781 agctaatcgc aaaagaagag gaagtgcctg tctataaaga cttggtgaca gagtctgata
    36841 ttttgaccac cttgagtcgc ttgtcaggta tccccgttca aaaactgact cagactgatg
    36901 ccaagaaata cttaaacttg gaagctgaac tgcacaaacg tgtcatcggt caagatcaag
    36961 ctgtttcaag cattagccgt gccattcgcc gtaatcagtc aggaattcgc agtcacaagc
    37021 gtccgatcgg ttcctttatg ttcctaggac ccacaggtgt cggtaagacc gagttggcca
    37081 aggctttggc agaagttctc tttgatgacg aatcagccct tatccgcttt gatatgagtg
    37141 agtatatgga gaaattcgca gccagccgtc taaatggagc tcctccaggc tatgtgggtt
    37201 acgaagaagg tggggagttg acagagaagg ttcgcaataa accctattcc gttctcctct
    37261 ttgatgaggt agagaaggct cacccagata tctttaatgt tctcttgcag gttctggatg
    37321 acggtgtctt gacagatagc aagggacgca aggtcgattt ttcaaatacc attatcatta
    37381 tgacatcgaa cctaggtgcg actgcccttc gtgatgataa gactgttggt tttggggcta
    37441 aggatattcg ttttgaccag gaaaatatgg aaaaacgcat gtttgaagaa ctgaaaaaag
    37501 cttatagacc ggaattcatc aaccgtattg atgagaaggt ggtcttccat agcctatcta
    37561 gtgaccatat gcaggaagtg gtgaagatta tggtcaagcc tttagtggca agtttggctg
    37621 aaaaaggcat tgacttgaaa ttacaagttt cagctctgaa attgttagca aatcaaggat
    37681 atgatctaga gatgggagct cgcccacttc gcagaaccct gcaaacagaa gtggaggaca
    37741 agttggcaga acttcttctt aagggagatt tagtggcagg cagcacactt aagattggtg
    37801 tcaaagcagg ccagttaaaa tttgatattg cataaaagaa taaaagtatc agcatctgac
    37861 cataagtcac agtggagtga aactcaatga aaatcaaaga gcaaactagg cagctagccg
    37921 caggttgctc aaaacactgg tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    37981 ttcgaagagt ataagctgca agatgaatga ttttcttgta ttgacgttgt tgttgacaaa
    38041 aagtagcgga taaatgaaat ccattccatt atcatagatg ataggctggt aggaaatttt
    38101 caaatagcat acaggaaata gatgtatgga gttctggtag tagaaaggga gagagatgaa
    38161 cattttagtt gcagatgacg aggaaatgat tagagaagga attgcagcat ttctgacaga
    38221 agagggttat catgtcatta tggctaagga tggacaagag gtcttggaaa aatttcaaga
    38281 tctccctatc catctcatgg tactggattt aatgatgcct aggaagagtg gttttgaagt
    38341 gttaaaagaa atcaatcaaa agcacgatat tcctgtcatc gtcttgagtg ctctgggaga
    38401 tgaaactact cagtcacagg tatttgatct ctatgctgat gatcatgtga caaaaccttt
    38461 ttctttggta ctgcttgtca agcgtattaa ggcgcttatc agacgttact acgtcataga
    38521 ggatatttgg cgatatcagg atgtaacagt ggattttacc tcttacaaag cacattataa
    38581 aaatgaagaa attgatctca aaccaaagga attactggta ctaaagtgtt tgattcagca
    38641 taaaaatcaa gttttaagta gagagcagat attggaagaa atttcaaaag atgtagctga
    38701 tttaccttgt gatagggtcg ttgatgtcta tattcgtact cttcgcaaaa aattagcttt
    38761 agattgtatc gtgactgtga aaaatgttgg gtataagatt agcttatgat aaaaaatcct
    38821 aaattattaa ccaagtcttt tttaagaagt tttgcaattc taggtggtgt tggtctagtc
    38881 attcatatag ctatttattt gacctttcct ttttattata ttcaactgga gggggaaaag
    38941 tttaatgaga gcgcaagagt gtttacggag tatttaaaga ctaagacatc tgatgaaatt
    39001 ccaagcttac tccagtctta ttcaaagtcc ttgaccatat ctgctcacct taaaagagat
    39061 attgtagata agcggctccc tcttgtgcat gacttggata ttaaagatgg aaagctatca
    39121 aattatatcg tgatgttaga tatgtctgtt agtacagcag atggtaaaca ggtaaccgtg
    39181 caatttgttc acggggtaga tgtctacaaa gaagcaaaga atattttgct tttgtatctc
    39241 ccatatacat ttttggttac aattgctttt tcctttgttt tttcttattt ttatactaaa
    39301 cgcttgctca atcctctttt ttacatttca gaagtgacta gtaaaatgca agatttggat
    39361 gacaatattc gttttgatga aagtaggaaa gatgaagttg gtgaagttgg aaaacagatt
    39421 aatggtatgt atgagcactt gttgaaggtt attcatgagt tggaaagtcg taatgagcaa
    39481 attgtaaaat tgcaaaatca aaaggtttcc tttgtccgcg gagcatcaca tgagttgaaa
    39541 acccctttag ccagtcttag aattatccta gagaatatgc agcataatat tggagattac
    39601 aaagatcatc caaaatatat tgcaaagagt ataaataaga ttgaccagat gagccactta
    39661 ttggaagaag tactggagtc ttctaaattc caagagtgga cagagtgtcg tgagaccttg
    39721 actgttaagc cagttttagt agatatttta tcacgttatc aagaattagc tcattcaata
    39781 ggtgttacaa ttgaaaatca attgacagat gctaccaggg tcgtcatgag tcttagggca
    39841 ttggataagg ttttgacaaa cctgattagt aatgcaatta aatattcaga taaaaatggg
    39901 cgcgtaatca tatccgagca agatggctat ctctctatca aaaatacatg tgcgcctcta
    39961 agtgaccaag aactagaaca tttatttgat atattctatc attctcaaat cgtgacagat
    40021 aaggatgaaa gttctggttt gggtctttac attgtgaata atattttaga aagctatcaa
    40081 atggactata gttttctccc ttatgaacac ggtatggaat ttaagattag cttgtagaca
    40141 gattagtttt ttattaaagt tcatataggg ttaacataag tgtgttattc tttgtataga
    40201 taaaagaaag gatactaata tggtattagc gattatttta gtaacattct ttattcgatt
    40261 gattttttta aagcgttcga tagagaatga gaaacgaatc cttagcaatg gcgggaaaga
    40321 atttggagtt gagaatacaa aacgattaac gttggctcat attgtttttt atctctcttg
    40381 cttggttgag gcaatggtgc acaagacaat ttttgatggc atgggcatgg ttggtttagt
    40441 cttgcttatt ttttctatgc tgatgttgat gttggtgatt cacttgttgg gagatatttg
    40501 gacagtgaag cttatgcttg tcaataatca caaatatgta gatcatatct tgtttaggac
    40561 agtaaaacat cctaattact ttttaaatat tcttcctgag ttgattggct tgaccttgtt
    40621 gagtcatgct tatgtgactt ttgttttagt ttttccagtt tatgcagtta ttttgtatcg
    40681 acgaatagct gaagaggaaa agctattaca tgaagttata atcccaaatg gaagcataaa
    40741 gagataaata caaaattcga tttatataca gttcatattg aagtaatata gtaatagact
    40801 tcatgcgaaa caaaatatgg tacaatagtt ctatgaatta tgaagcaagg ttgagaatat
    40861 ttttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
    40921 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
    40981 ttgcaggaag tctaatgtta agaaaaatat tggagaaaat aaacatgttt gcatcaaaaa
    41041 gcgaaaaaaa agtacattat tcaattcgta aatttagtat tggagtagct agtgtagctg
    41101 ttgccagtct ttttatggga agtgtggttc atgcgacaga gaaagaggga agtacccaag
    41161 cagccacttc ttctaatatg gcaaagacag aacataggaa agctgctaaa caattcgatg
    41221 aatatataaa caaaatgatc caattagata gaagaaaaga taccc
//
LOCUS       DAVFJR010000014        40517 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVFJR010000014 DAVFJR010000000
VERSION     DAVFJR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.015"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..300
                     /locus_tag="VU722_000970"
     CDS             <1..300
                     /locus_tag="VU722_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein H domain protein"
                     /protein_id="HEU1771974.1"
                     /translation="ERAISQADQLLDYKSWSEEDRKMFSQLRMREEQALLAHDYSLEQ
                     AEEKGLERGRAEGLERGLERGKLFAFLDMVRQGLLTSEVASQQLGMTVAEFEALL"
     gene            1331..1783
                     /locus_tag="VU722_000971"
     CDS             1331..1783
                     /locus_tag="VU722_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU1771975.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1802..3139
                     /locus_tag="VU722_000972"
     CDS             1802..3139
                     /locus_tag="VU722_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU1771976.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            3218..4102
                     /locus_tag="VU722_000973"
     CDS             3218..4102
                     /locus_tag="VU722_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1771977.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            4102..4935
                     /locus_tag="VU722_000974"
     CDS             4102..4935
                     /locus_tag="VU722_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1771978.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4953..7046
                     /gene="nanB"
                     /locus_tag="VU722_000975"
     CDS             4953..7046
                     /gene="nanB"
                     /locus_tag="VU722_000975"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU1771979.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHSNELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            7058..8161
                     /locus_tag="VU722_000976"
     CDS             7058..8161
                     /locus_tag="VU722_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU1771980.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNTEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHRAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            8334..9032
                     /locus_tag="VU722_000977"
     CDS             8334..9032
                     /locus_tag="VU722_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU1771981.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPHEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVKAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            9051..9972
                     /locus_tag="VU722_000978"
                     /pseudo
     CDS             9051..9972
                     /locus_tag="VU722_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            10097..11425
                     /locus_tag="VU722_000979"
     CDS             10097..11425
                     /locus_tag="VU722_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1771982.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11677..12543
                     /locus_tag="VU722_000980"
     CDS             11677..12543
                     /locus_tag="VU722_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1771983.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSITKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12559..13398
                     /locus_tag="VU722_000981"
     CDS             12559..13398
                     /locus_tag="VU722_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1771984.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIIIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13458..13802
                     /locus_tag="VU722_000982"
     CDS             13458..13802
                     /locus_tag="VU722_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1771985.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIINGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLGADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14089..14733
                     /locus_tag="VU722_000983"
     CDS             14089..14733
                     /locus_tag="VU722_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU1771986.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            14902..15819
                     /locus_tag="VU722_000984"
     CDS             14902..15819
                     /locus_tag="VU722_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU1771987.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            15837..16721
                     /locus_tag="VU722_000985"
     CDS             15837..16721
                     /locus_tag="VU722_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1771988.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFQEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(16737..17588)
                     /locus_tag="VU722_000986"
     CDS             complement(16737..17588)
                     /locus_tag="VU722_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU1771989.1"
                     /translation="MDKPDIATVIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            17796..19838
                     /gene="pbp2b"
                     /locus_tag="VU722_000987"
     CDS             17796..19838
                     /gene="pbp2b"
                     /locus_tag="VU722_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU1771990.1"
                     /translation="MRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEK
                     KLASASQTKVTSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKEIAKKLLT
                     YVSISSPNLTERQLADYYLSDPEIYKKTVEALPSEKRLDSDGNRLSESELYNNAVDSV
                     PTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISIS
                     TSWDRKILETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETL
                     QGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELGN
                     GGAKYSEGVYAVALNPKTGAVLSMSGLKHDLKTGELTPDSLGTVTNVFVPGSVVKAAT
                     ISSGWENGVLSGNQTLTDQPIVFQGSAPIYSWYKLAYGSFPITAVEALEYSSNAYMVQ
                     TALGIMGQTYQPNMFVGTSNLETAMGKLRATFGEYGLGAATGIDLPDESTGFVPKEYS
                     FANYITNSFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGDLIQQL
                     QPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVA
                     DGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN"
     gene            19849..20445
                     /gene="recR"
                     /locus_tag="VU722_000988"
     CDS             19849..20445
                     /gene="recR"
                     /locus_tag="VU722_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU1771991.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            20621..21664
                     /locus_tag="VU722_000989"
     CDS             20621..21664
                     /locus_tag="VU722_000989"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU1771992.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSQTPGQEDRLMTNATIDWDKKVSPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFQYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKEEIFLNELNTMPGFTQWSMYPLLWDNMGISYPDLIEHLVAL
                     AKESFDKREAHLL"
     gene            21749..23122
                     /locus_tag="VU722_000990"
     CDS             21749..23122
                     /locus_tag="VU722_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU1771993.1"
                     /translation="MKLTIHEVAQAVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTVIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            23109..23720
                     /locus_tag="VU722_000991"
     CDS             23109..23720
                     /locus_tag="VU722_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1771994.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            23811..24515
                     /locus_tag="VU722_000992"
     CDS             23811..24515
                     /locus_tag="VU722_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU1771995.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            24734..26107
                     /gene="ftsA"
                     /locus_tag="VU722_000993"
     CDS             24734..26107
                     /gene="ftsA"
                     /locus_tag="VU722_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU1771996.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26124..27383
                     /gene="ftsZ"
                     /locus_tag="VU722_000994"
     CDS             26124..27383
                     /gene="ftsZ"
                     /locus_tag="VU722_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU1771997.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQVSAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27388..28059
                     /locus_tag="VU722_000995"
     CDS             27388..28059
                     /locus_tag="VU722_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU1771998.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28069..28608
                     /locus_tag="VU722_000996"
     CDS             28069..28608
                     /locus_tag="VU722_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU1771999.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            28608..28871
                     /locus_tag="VU722_000997"
     CDS             28608..28871
                     /locus_tag="VU722_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU1772000.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            28868..29653
                     /locus_tag="VU722_000998"
     CDS             28868..29653
                     /locus_tag="VU722_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU1772001.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPLAEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLKLLQDKGQTKKEKKKITVQLLLSK"
     gene            29662..30451
                     /locus_tag="VU722_000999"
                     /pseudo
     CDS             29662..30451
                     /locus_tag="VU722_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
     gene            30799..33591
                     /locus_tag="VU722_001000"
     CDS             30799..33591
                     /locus_tag="VU722_001000"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU1772002.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNSPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLISLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTVVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDTKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDAVAYEELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAETFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTMAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAGGFEEK"
     gene            33774..39593
                     /locus_tag="VU722_001001"
     CDS             33774..39593
                     /locus_tag="VU722_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEU1772003.1"
                     /translation="MRQTNVRGSLSLRGFRKLRTGAIVATGVILLGLGFSAPTASVSE
                     QDGVWVARTVAEVKADIQKEGDLFKYVIKWGDTLSVISEASNIPVDVLQEMNQASGKN
                     LFLPYNELYFTEAETVSDTVTKHKIVIKESGASGEVRTYEVLLKKDQETKAVTFELTD
                     VTEKVEKMTVNYSPVYQPVSVPVVERAEESVEEPALVAPAVTSPEVKEETEDPVVLKA
                     EEAATTPATKETAPEVVTPAEPNAETPAPKVEAPTESSEPKGTEPEVAKPAGDSVSST
                     SESNEDGNSGDSTHSTLTSDETKPEEVESTSVTDNVPSNAGTTNQPLTPTSNSDDSAP
                     KEVANGTEGKVEAPKVEEAVSEGEEGNAEITNNPSTGATPSSDETTEQSGTPAPKPEE
                     EAPVATETSAASAESTESAPVVAKPAEPKAETPEATITGDEGKESEESGTSATVESTP
                     AGEEGKAEDSVSSTESSSTASEGESTATQPAVEAGTDSTSEAEELATTETATTPKTEE
                     PEAVAPAPEAPSESDSKEEDSAAGDTTVTEEQPAAETVSEGGSPATQPAGEEGKSEKE
                     PKVEGQPSGTESATPEQHTNIEETTEKQSGATSENSGDSLVSDEPAASSGISTSSGTE
                     GAETIDTETIAEKSEIPSPAEEGSAKEEKEVIKKLELRNISSVELYSKEGDKYRHVTS
                     LATLPSNPETYFMKVKSENFKDVMLPVTSITNDNKDNRDVYKIVASVKNLIQHENNKV
                     LENYTYYLSKTQQGETGVYTSFKNLVDAMNRDSYGEFRLGATMDAREVELPDGQESYV
                     KNVFHGRLIGQNSNKYYAIYNLKKPLFNALSNARVQNLSLKDVNISAKDDTATLAKEA
                     NNNTHIDNVHSDGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLV
                     GKLSGPNGLIDKSIASIDLASNATRGDQSIGGIAGSVIDNAVISSSYAEGKLNNVQPF
                     ANVGGVVGDLWDPVGGLEKSGQLSNVLSDVNVTNGNAIAGKHFDHMKATNVYSNKNNK
                     VVNVVQENDEILTKDSVVQRGEVLEDEQIKEKKAAFVTKNTVKTEDFNFSSRYVTDYK
                     NLENADSSKEKVYKNIEKLLPFYNSETIVKYGNLVETSSNLYNKELLSVVPMKDKEVI
                     SDINKNKSSINKLLLYYADNSYETLNVNYQSDFSNVAEYSIGGTNLIYTPNTLLRDYN
                     NILDGVLPVLETVDYKSDAIRKVLDVSNDVSLTELYLEEQFNTTKNNLRDSLTKLLTA
                     DAAISENSNSIIDNYVIEKIKNNKEALLLGLTYLERWYNFKYGETKAKDLVMYHLDFF
                     GKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLSKNYKTNNLFDALEKYRKVFVPD
                     KTNNEWFKEQTKAYIVEEKSTIKEVNDKQSKAGTPQSIGVYDRLTSPSWKYPSMVLPL
                     LTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTNLNDYVEAKAREAAVRFRDHYDYW
                     YKILDNNNKEKLYRSVLVYDAFRFGADDKGERETKQANFETDHPAIKHFFGPAGNNVV
                     HNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYA
                     KGLLQAPDHPDDPTITINSILKYEESEDPTRLQVKDPTKRFNNAEDLQKYMYNMFDVI
                     YMLEYLEGNAVVKLDISKKNELLRKIENKFETDPDGSNVYATNVVRYLKPEELTKLTS
                     FNSLIENDVITRRGYENGNDNTFKRNGYYTIKLFSPIYSALSNNEGTPGDLMGRRMAF
                     ELLAAKGFKDGMVPYISNQYAEEAKAKGKVIKSYGKEVGNVTDELVLQKIFNNRYSSW
                     VEFKKAMYNERIAKFKKLMSISFDNPNGNWFRKDRVTIKNIEDLQRMITTAVNEDAED
                     YLVNIYPERSRVLKLKKAIFKAYLDQTNDFRSSIFDEEK"
     gene            39752..40444
                     /locus_tag="VU722_001002"
     CDS             39752..40444
                     /locus_tag="VU722_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU1772004.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
BASE COUNT        12961 a         6957 c         8753 g        11846 t
ORIGIN      
        1 gagcgagcca tcagccaagc agaccaactg ctggactaca agagctggtc cgaggaggac
       61 agaaaaatgt ttagtcaact acgtatgcga gaagaacagg cattattggc tcatgactat
      121 tccttggaac aagctgagga aaaagggttg gagagaggtc gtgcagaagg acttgaacgt
      181 ggtcttgaac gtggaaaact ttttgccttt ctggatatgg ttcgccaagg acttctgact
      241 tccgaggttg ccagtcagca gttgggcatg accgttgctg agtttgaggc gttgttgtaa
      301 gatcagcaat aatagacagg aaaaccatct ggtcaagatg gcgttcttgg aattaaaaaa
      361 ctctaggtat aaaatcttaa aaattacaaa cacgcatagt atcaggggat taagaaacct
      421 tgatactatg cgttttatag tgcattgaat ctacattagt acactatagt tgattgaaaa
      481 cagaatagta taccgcagct tctaaatcct tgttataaat ttgatttgac tttcctaatc
      541 gatttattct catcttattt caatctgcta tatttacttc actttctcct aaaattgact
      601 ttcttgtttt cttatcttgt ccactcgaaa caagtattgt aagaatttga ttatttttga
      661 aagtactttt aatatacttg atatagttaa aaaagatttg aaactaaatt ccaaattaga
      721 aaaagacttg aaatactaaa aaaaaaaaag tatactctaa ttgaaaacgg taacaaaact
      781 aatttagaga atgaaatata gagtatttct ctcttaaaag tttttggtga aacgagatgt
      841 agaaaggaga tttagccaaa gagtctatta gtgctagaat aatagattag aattatttta
      901 gaaaaacgaa gtgagcagct tataaattca agtccccaaa tagattcata ctagtatctt
      961 ttgcaaaaaa taaagggcga cttccttcat gaatatcaat ttcatctata aggaaggtag
     1021 ctaattgaac taacttattt attctgtttg tcgctagaaa aatcagacct ccttgtgaag
     1081 attgaggaga tacttaatga aaatcaaaga agaaactagc aagctagtag cagattgccc
     1141 aaaacaccgc tttgaggttg tagataagac tgacgtatat aatccaaggt gaagcgactg
     1201 tggtttgaag agattttcaa agagtatagg ctagagagta gtgtttttat gtccttctag
     1261 tagaaaatgc tagacagaag aatggggaac ttggatagga aaaatagatt gagaaaggag
     1321 gttagaagag atgattatta caaaaattag ccgtttagga acttatgtgg gagtaaatcc
     1381 acattttgca acattaatag attttctaga aaaaacagga ctagaaaatt taacagaagg
     1441 ttcgattgct atcgatggta atcgattgtt tgggaattgc tttacttatc tagcagatgg
     1501 tcaagcaggg gctttctttg aaacacacca aaaatatttg gatattcatt tagttttgga
     1561 aaacgaagaa gccatggctg ttacatcgcc ggaaaatgta agcgttaccc aagagtatga
     1621 tgaagagaaa gatattgaat tatacacagg gaaagtggaa cagttggttc atttgagagc
     1681 tggcgaatgc ctcatcactt ttccagaaga tttacatcaa cccaaggttc gtataaatga
     1741 tgaacctgtg aaaaaagttg tctttaaagt tgcgatttct taatgtagaa agagaagaac
     1801 gatgaaaaaa atgagaaagt ttttatgtct agctggaatt gcgctagcgg ctgttgcctt
     1861 ggtagcttgt tcaggaaaaa aagaagctac aactagtact gaaccaccaa cagaattatc
     1921 tggtgagatt acaatgtggc actcctttac tcaaggaccc cgtttagaaa gtattcaaaa
     1981 atcagcagat gctttcatgc aaaagcatcc aaaaacgaaa atcaagattg aaacattttc
     2041 ttggaatgac ttctatacta aatggactac aggtttagca aatggaaatg tgccagatat
     2101 cagtacagct cttcctaacc aagtaatgga aatggtcaac tcagatgctt tggttccgct
     2161 aaatgattct atcaagcgta ttggacaaga taaatttaac gaaactgcct taaatgaagc
     2221 aaaaatcgga gatgattact actctgttcc tctttattca catgcacaag tcatgtgggt
     2281 tagaacagat ttgttaaaag aacataatat tgaggttcct aaaacttggg atcaactcta
     2341 tgaagcttct aaaaaattga aagaagctgg agtttatggc ttgtctgttc cgtttggaac
     2401 aaatgactta atggcaacac gtttcttgaa cttctacgta cgtagtggcg gaggaagcct
     2461 cttaacaaaa gatcttaaag cagacttgac aagccaactt gctcaagatg gtattaaata
     2521 ctgggttaaa ttgtataaag aaatctcacc tcaagattct ttgaacttta atgtccttca
     2581 acaagctacc ttgttctatc aaggaaaaac agcatttgac tttaactctg gcttccatat
     2641 cggaggaatt aatgccaaca gtcctcaatt gattgattcg attgatgctt atcctattcc
     2701 aaaaatcaaa gagtctgata aagaccaagg aattgaaacc tcaaacattc caatggttgt
     2761 ttggaaaaat tcaaaacatc cagaagttgc taaagcattc ttagaagcac tttataatga
     2821 agaagactac gttaaattcc ttgattcaac tccagtaggt atgttgccaa ctattaaggg
     2881 gattagcgat tctgcagcct ataaagaaaa tgaaactcgt aagaaattta aacatgctga
     2941 agaagtaatt actgaagctg ttaaaaaagg tactgctatt ggttatgaaa atggaccaag
     3001 tgtacaagct ggtatgttga ctaaccaaca cattattgaa caaatgttcc aagatatcat
     3061 tacaaatgga acagatccta tgaaagcagc aaaagaagca gaaaaacaat taaacgattt
     3121 atttgaggct gttcagtaga tgtaaaagac tagaaaatag gtgggctagt gagctgaaaa
     3181 gctctagccc aatcttgtaa aagaagggag aaggagaatg gttaaagaac gtaatttaac
     3241 tcgctggata tttgttttgc cagctatgat tatcgtagga ttactctttg tttatccgtt
     3301 tttctcgagt attttttata gctttaccaa taagcatttg attatgccta attataaatt
     3361 tgttggtttg gctaactata aagctgtgct atcagatccc aacttcttta atgcgttctt
     3421 taattcaatt aagtggaccg ttttctcatt agttggtcaa gttttagtag ggtttgtatt
     3481 ggctttagct cttcacagag tacgccactt caagaaatta tataggacct tattgattgt
     3541 tccttgggca tttcctacca tcgttattgc cttttcttgg cagtggattc taaacggggt
     3601 ttatggctac ttacctaatc taatcgtaaa attaggttta atggaacata cacctgcatt
     3661 tttgacagat agtacatggg cattcctatg tttggtgttt atcaacattt ggtttggagc
     3721 accaatgatt atggttaatg tgctttcagc tttgcaaaca gtaccagaag aacaatttga
     3781 ggctgctaag atagatggtg cttcaagttg gcaggtgttc aagtttatcg tctttccaca
     3841 tattaaagtg gttgtaggac ttctagttgt tttgagaact gtatggatct ttaataactt
     3901 tgacattatc tacctaatta ctggtggtgg accagccaat gctacaacga cgcttccaat
     3961 ttttgcttac aacctgggtt ggggaactaa attgttgggt cgtgcttcag cagttacagt
     4021 attgctcttt atcttcttgg tggcgatttg ctttatctac tttgctatca tcagtaagtg
     4081 ggaaaaggag ggtagaaaat aatgaagaag aaatccagta tttatttaga tattctctca
     4141 catgtacttt tagttggtgc gaccatcgtt gcaattttcc cattggtatg gattatcata
     4201 tcttctgtca aagggaaagg ggaattaact cagtatccaa cacgattttg gcctgaacag
     4261 tttacattag attatttcac tcatgttatc aacgatttgc acttcattga taatattcga
     4321 aacagtttaa tcattgcctt ggctacaacc ctcattgcga ttattatttc tgctatggca
     4381 gcctatggta ttgttcgatt ctttcctaaa ttgggagcaa tcatgtcgag actactcgtc
     4441 attacctaca ttttcccacc aattttgtta gcaattccct attcaattgc cattgctaaa
     4501 gttgggttaa caaatagttt atttggcttg atgatggttt atctatcttt tagtgttcca
     4561 tatgcagttt ggctcttagt tggatttttc caaacagttc caattggaat tgaagaagcg
     4621 gctagaattg atggtgcaaa taaatttgtt acgttttata aagttgtgct accgattgta
     4681 gcaccaggta ttgtagcaac agctatttat acatttatca atgcttggaa tgaattcctg
     4741 tatgccttga ttttgattaa caatacagga aagatgacag tagcagtagc ccttcgttca
     4801 cttaatggtt cagaaatact agactgggga gatatgatgg cagcgtctgt tattgtagtt
     4861 cttccatcaa ttattttctt ctctatcatc caaaataaga ttgcaagtgg attatcagaa
     4921 ggatctgtga agtagacgaa agaaggaaaa aaatgaataa aagaggtctt tattcaaaac
     4981 taggaatttc tgttgtaggc attagtcttt taatgggagt ccccactttg attcattcga
     5041 atgaattaaa ctatggtcaa ctgtccatat ctcctatttt tcaaggaggt tcatatcaac
     5101 tgaacaataa gagtatagat atcagccctt tgttattaga taaattgtct ggagagagtc
     5161 agacagtagt aatgaaattt aaagcagatg aaccaaactc tcttcaagct ttgtttggcc
     5221 tatctaatag taaagcaggc tttaaaaata attacttttc aattttcatg agagattctg
     5281 gtgagatagg tgtagaaata agagacgccc aaaagggaat aaattattta ttttccagac
     5341 cagcttcatt atggggaaaa cataaaggac aggcagttga aaatacacta gtatttgtat
     5401 ctgattctaa agataaaaca tacacaatgt atgttaatgg aatagaagtg ttctctgaaa
     5461 cagttgatac atttttgcca atttcaaata taaatggtat agataaggca acactaggag
     5521 ctgttaatcg tgaaggtaag gaacattacc ttgcaaaagg aagtattgat gaaatcagtc
     5581 tatttaacaa agcaattagt gatcaggaag tttcaaatat tcccttgtca aatccatttc
     5641 agttaatttt ccaatcagga gattctactc aagctaacta ttttagaata ccgacactat
     5701 atacattaag tagtggaaga gttctatcaa gtattgatgc acgttatggt gggactcatg
     5761 attctaaaag taagattaat attgccactt cttatagtga tgataacggg aaaacgtgga
     5821 gtgagccaat ttttgctatg aagtttaatg actatgagga gcagttagtt tactggccac
     5881 gagataataa attaaagaat agtcaaatta gtggaagtgc ttcattcata gattcatcca
     5941 ttgttgaaga taaaaaatct gggaaaacga tattactagc tgatgttatg cctgcgggta
     6001 ttggaaataa taatgcaaat aaagccgact caggttttaa agaaataaat ggtcattatt
     6061 atttaaaact aaagaagaat ggagataacg atttccgtta tacagttaga gaaaatggtg
     6121 tcgtttatga tgaaacaact aataaaccta caaattatac tataaatgat aagtatgaag
     6181 ttttggaggg aggaaagtct ttaacagtcg aacaatattc ggttgatttt gatagtggct
     6241 ctttaagaga aaggcataat ggaaaacagg ttcctatgaa tgttttctac aaagattcgt
     6301 tatttaaagt gactcctact aattatatag caatgacaac tagtcagaat agaggagaga
     6361 gttgggaaca atttaagttg ttgcctccgt tcttaggaga aaaacataat ggaacttact
     6421 tatgtcccgg acaaggttta gcattaaaat caagtaacag attgattttt gcaacatata
     6481 ctagtggaga actaacctat ctcatttctg atgatagtgg tcaaacatgg aagaaatcct
     6541 cagcttcaat tccgtttaaa aatgcaacag cagaagcaca aatggttgaa ctgagagatg
     6601 gtgtgattag aacattcttt agaaccacta caggtaagat agcttatatg actagtagag
     6661 attctggaga aacatggtcg gaagtttcgt atattgatgg aattcaacaa acttcatatg
     6721 gcacacaagt atctgcaatt aaatattctc aattaattga tggaaaagaa gcagtcattt
     6781 tgagtacacc aaattctaga agtggccgta agggaggtca attagttgtc ggtttagtca
     6841 ataaagaaga tgatagtatt gattggaaat atcactatga tattgatttg ccttcgtatg
     6901 gttatgccta ttctgcgatt acagaattgc caaatcatca tataggtgta ctgtttgaaa
     6961 aatatgattc gtggtcgaga aatgaattgc atttaagcaa tgtagttcag tatatagatt
     7021 tggaaattaa tgatttaaca aaataaagga gaaaaacatg gttaaatacg gtgttgttgg
     7081 aacagggtat tttggagctg aattggctcg ctacatgcaa aagaatgatg gagcagagat
     7141 tactcttctc tatgatccgg ataatacaga ggcgattgca gaagaattgg gagcaaaagt
     7201 agcaagttcc ttagatgagt tggtttctag cgatgaagta gattgtgtca tcgtcgcaac
     7261 tccaaataat cttcataagg aaccggttat taaggctgca cagcatggta aaaatgtttt
     7321 ctgtgaaaaa ccaattgcgc tttcttatca agattgtcgc gagatggtag atgcatgtaa
     7381 agaaaacaat gtaaccttta tggcaggaca tattatgaat ttctttaatg gtgttcatcg
     7441 tgcaaaagaa ctcattaatc aaggagttat cggagacgtt ctatattgtc atacagctcg
     7501 taatggttgg gaagaacaac aaccgtcagt atcatggaaa aaaattcgtg aaaaatcagg
     7561 tggtcacttg tatcaccaca tccatgaatt ggattgcgtt caattcctta tggggggcat
     7621 gcctgaaact gtaaccatga caggtggaaa tgtggcccat gaaggtgaac atttcggtga
     7681 tgaagatgat atgatttttg tcaatatgga attttctaat aagcgttttg ccttgttaga
     7741 atggggttca gcttatcgtt ggggtgaaca ttatgtctta atccaaggaa gcaaaggtgc
     7801 catccgctta gacttattca actgtaaagg aactcttaag ctagatgggc aagaaagcta
     7861 tttcttgatt cacgaatcgc aagaagaaga tgatgatcgg actcgtatct atcatagtac
     7921 agagatggat ggagcaattg cttatggtaa accaggtaaa cgtactccat tatggctatc
     7981 atctgtcatt gataaagaaa tgcgctatct gcatgagatt atggaaggag ctccagtatc
     8041 agaagaattt gcaaaacttt tgacaggtga agctgcccta gaagcaattg ctactgcaga
     8101 tgcttgtacc cagtctatgt ttgaagatcg caaagtaaaa ttgtcagaaa ttgtaaaata
     8161 aattttggta ttctcctatt ataggtcgac ttgctcctct gaaagtactt ttagaggagc
     8221 tgtttgactt ggctagtttt tgaaactgaa atctattata ctacaaacta ttgaaagcgt
     8281 tttaatttta aggtataata atctcataga aataaagaaa aggaggaaag aggatgccac
     8341 agattagcaa agaagccttg attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg
     8401 ctcttcctca tgaaccgctt tatacagaag cgggaggggt gattcccttg ctggtcaaag
     8461 cggctgagca aggtggagca gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa
     8521 ttaaggaagt cactaaactt ccaatcattg ggattatcaa acgtgattat ccacctcatg
     8581 aacccttcat cacggctact atgaaagaag ttgatgaatt ggcagaactg gacatcgagg
     8641 tgattgctct ggattgtacc aagcgtgaac gctacgatgg tttggaaatt caagagttca
     8701 ttcgtcaggt taaggagaaa tatcctaatc agcttttgat ggctgatact agtatcttcg
     8761 aagaagggct agcagctgta aaagcaggaa ttgactttgt cggaacaacc ttatcaggct
     8821 acacatccta cagtccaaaa gtagacggtc cagattttga attgattaag aaactctgtg
     8881 atgccggtgt agatgtcatt gcagaaggaa aaattcatac accagaacaa gccaaacaaa
     8941 tccttgaata tggagtgcga ggcatcgttg ttggtggcgc tattactaga ccaaaagaga
     9001 ttacagaacg cttcgttgct agtcttaaat aagatgtgag ggggagtttt atgtttaaag
     9061 ttttacaaaa agttggaaaa gcttttatgt tacctatagc tatactttct gcagcaggtc
     9121 tacttttggg gattggtggt gcactttcaa acccaaccac gatagcaact tatccaatac
     9181 tagacaatag tatttttcaa tcaatattcc aagtaatgag ctctgcagga gaggttgtat
     9241 tcagtaattt gtcactactt ctctgtgtgg gattatgtat tggcttagcg aaacgagata
     9301 aaggaaccgc tgcgttagca ggagtaactg gttacttagt tatgactgta acgatcaaag
     9361 ctttggtaaa actttttatg gcagaaggat ctgcaattga tactggagtt attggagcat
     9421 tagttgtcgg aatagttgcc gtatatttgc acaatcgata taacaatatt caattacctt
     9481 ccgctttagg attctttgga ggttcacgct tcgttcctat tcactttatt tggaattttg
     9541 caggggaacg ctaagacgaa ttgggttctt cagattccat ttggacttat ttggagtgtt
     9601 ttgtattata ttatttttag atggttcatt actcaattca acgttctaac gccaggacga
     9661 ggagaagaag tagattctaa agaaatttct gaatccgcag attcaacttc aaatactgca
     9721 gattatttaa aacaggatag cctacaaatt atcagagcct tgggtggatc aaataatata
     9781 gaagatgtag atgcttgtgt gacacgttta cgtgtagctg taaaagaagt taatcaagtt
     9841 gataaagcac ttttaaaaca aattggtgca gttgatgtct tagaagtgaa gggtggcatt
     9901 caagcaatct atggagcaaa agcaatctta tataaaaata gtattaatga aattttaggt
     9961 gtagatgatt aagtacttac tgacttaata aaaaacagag gagagtgatg gatgagtagg
    10021 atgaaatgaa atcgcataca agaaataaag aactcattat ccaagttgga tacgcttatt
    10081 acataggaga atacaaatga aatttagaaa attagcttgt acagtacttg cgggtgctgc
    10141 ggttcttggt cttgctgctt gtggcaattc tggcggaagt aaagatgctg ccaaatcagg
    10201 tggtgacggt gccaaaacag aaatcacttg gtgggcattc ccagtattta cccaagaaaa
    10261 aactggtgac ggtgttggaa cttatgaaaa atcaatcatc gaagcgtttg aaaaagcaaa
    10321 cccagatata aaagtgaaat tggaaaccat cgacttcaag tcaggtcctg aaaaaatcac
    10381 aacagccatc gaagcaggaa cagctccaga cgtactattt gatgcaccag gacgtatcat
    10441 ccaatacggt aaaaacggta aattggctga gttgaatgac ctcttcacag atgaatttgt
    10501 taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa gctggagaca aggcttatat
    10561 gtatccgatt agttctgccc cattctacat ggcaatgaac aagaaaatgt tagaagatgc
    10621 tggagtagca aaccttgtaa aagaaggttg gacaactgat gattttgaaa aagtattgaa
    10681 agcacttaaa gacaagggtt acacaccagg ttcattgttc agttctggtc aagggggaga
    10741 ccaaggaaca cgtgccttta tctctaacct ttatagcggt tctgtaacag atgaaaaagt
    10801 tagcaaatat acaactgatg atcctaaatt cgtcaaaggt cttgaaaaag caactagctg
    10861 gattaaagac aatttgatca ataatggttc acaatttgac ggtggggcag atatccaaaa
    10921 ctttgccaac ggtcaaacat cttacacaat cctttgggca ccagctcaaa atggtatcca
    10981 agctaaactt ttagaagcaa gtaaggtaga agtggtagaa gtaccattcc catcagacga
    11041 aggtaagcca gctcttgaat atcttgtaaa cgggtttgca gtattcaaca ataaagacga
    11101 caagaaagtc gctgcatcta agaaattcat ccagtttatc gcagatgaca aagagtgggg
    11161 acctaaagac gtagttcgta caggtgcttt cccagtccgt acttcatttg gaaaacttta
    11221 tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa tactactcac catactacaa
    11281 cactattgat ggatttgctg aaatgagaac actttggttc ccaatgttgc aatctgtatc
    11341 aaatggtgac gaaaaaccag cagatgcttt gaaagccttc actgaaaaag cgaacgaaac
    11401 aatcaaaaaa gctatgaaac aatagtcctt agttattcta taaaaagtag ttttttaaag
    11461 aacctaagag tgtatacccc cttttccctc tacacagata gtgtaagaaa agggggcttt
    11521 tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag ttcttacata agcgaatcat
    11581 aaaaaatttc attttgattt taaaacagtt caagaaagtc aaaaaattat tctatttgaa
    11641 agagaggtgc cgactgtgaa agtcaataaa atccgtatgc gggaaacagt gatttcctac
    11701 gctttcctag caccagtatt attcttcttt gtcatctttg tgttggctcc gatggtgatg
    11761 ggcttcatta caagtttctt taactactca ataactaaat ttgagtttgt aggcttggat
    11821 aactatatcc gtatgtttaa agatcctgtc tttacaaaat ctctgattaa cacagttatt
    11881 ttggttattg gatctgtacc agttgttgtt ctattctcac tctttgtagc atctcagacc
    11941 tatcatcaaa atgtcattgc cagatccttc taccgtttcg tcttcttcct tcctgttgta
    12001 acgggtagtg ttgccgtgac agttgtttgg aaatggattt atgacccact atcagggatt
    12061 ctaaactttg tccttaagtc aagccacatc atcagccaaa acatttcttg gttgggagat
    12121 aaaaactggg cattgatggc gattatgatt attctcttga ccacttcagt tggtcagccc
    12181 atcatccttt atatcgctgc catggggaat attgacaatt cactggttga agcggcgcgt
    12241 gttgatggtg caactgagtt tcaagttttt tggaagatta aatggccaag ccttcttcca
    12301 acaactcttt atattgcaat catcacaaca attaactcat tccagtgttt cgccttgatt
    12361 cagcttttga catctggtgg tccaaactac tcaacaagta ccttgatgta ctacctttac
    12421 gaaaaagcct tccaattgac agaatacggc tatgccaaca caattggtgt cttcttggca
    12481 gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac ttggaaacga cgtagaatac
    12541 taaagaaagg agacagctat gcaatctaca gaaaaaaaac cattaacagc ctttactgtt
    12601 atttcaacaa tcattttgct cttgttgact gtgctgttca tctttccatt ctactggatt
    12661 ttgacagggg cattcaaatc acaacctgat acaattatta ttcctcctca gtggttccct
    12721 aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc agaaccctgc cttgcaatgg
    12781 atgtggaact cagtatttat ctcattggta accatgttct tagtttgtgc aacctcatct
    12841 ctagcaggtt atgtattggc taaaaaacgt ttctatggtc aacgcattct atttgctatc
    12901 tttatcgctg ctatggcgct tccaaaacaa gttgtccttg taccattggt acgtatcgtc
    12961 aacttcatgg gaatccacga tactctctgg gcagttatct tgcctttgat tggatggcca
    13021 ttcggtgtct tcctcatgaa acaatttagt gaaaatattc ctacagagtt gcttgaatca
    13081 gctaagattg acggttgtgg tgagattcgt actttttgga gcgtagcctt cccaattgta
    13141 aaaccagggt ttgcggctct tgcaatcttc accttcatca atacttggaa tgactacttc
    13201 atgcagttgg taatgttgac ttcacgtaac aatttgacca tctcacttgg ggttgcgacc
    13261 atgcaggccg aaatggcaac caactatggt ttgattatgg caggagctgc ccttgctgct
    13321 gttccaatcg tcacagtctt cctagtcttc caaaaatcct tcacacaggg tattactatg
    13381 ggagcggtca aaggataata ctctaccatg aaattgatct ttgtgaggta gagaaatgag
    13441 aataaaatat ttaaaaattg gtatcttcta agtatgctgc aagagctagt ttcttagatg
    13501 gacaggggat tacagttgat gagatggctt ggataattaa tggcattgtg aatggattga
    13561 ttggtagata cataaaatta ggtacttatg cagctaagta tggtattagt atggcgcgct
    13621 cgatcttaag tagggcagct gcaactgcgg cagcaagagt aggattattg actaagattt
    13681 ttggatggat tttacgaata gctgtgctcg gagctgatgt atatggtaat tttgccaaca
    13741 atattgctgt agcttgggat gcacatgata aaatccctaa caatggtcgt ataaactttt
    13801 aaaatgcgag aatgaaagca ctttgtattt ttttattgaa tatgttagct tggacagtgc
    13861 ttgcaatgac agtccgtgga gggctagatg gatttaatga gcatacttgg agtactattt
    13921 taattgcttc gctgtccggg atatatatag attatatgtc catagataaa agtagaaaaa
    13981 agtccaaaag aaaaaagaaa aaatagattt gttcatggta gggacttatg aaagctttac
    14041 tgacaaaaaa gaaaacagtt tacaaagaaa aatgatggag gagcaaacat ggcacaaaaa
    14101 ggagtaagcc ttatcaaggc agcatttgat acagacaact ttctcatgcg ttttagtgag
    14161 aaagtcttgg acatcgtgac agccaatctt ctttttgtcg tctcttgttt gcccatcgtg
    14221 acgattggag tggctaaaat cagcctctac gagaccatgt ttgagattaa gaagagcaga
    14281 cgggtgcctg tttttaaaat ctatctaaga tctttcaagc aaaatctgaa actaggtctt
    14341 cagctgggtt taatggagtt aggaattgtg tttcttaccc tttcagatct ctatcttttc
    14401 tggggtcaaa cagctctgcc cttccaattg ctgaaagcca tttgtttagg tattctgatt
    14461 tttcttacta tcgtgatgct ggctagttac cctatcgcgg cacgttatga cctatcttgg
    14521 aaagaaattc ttcaaaaagg gcttatcttg gcaagtttta actttccttg gttcttcctc
    14581 atgttagcca ttcttgtcct cattgtgatg gttctctatc tgtccgcctt cagtctactt
    14641 ttaggtggct cagtcttcct gctttttggg tttggactat tggtctttat ccagactgga
    14701 ttgatggaga aaattttcgc aaaataccaa taggagcctt atttctgaaa ctactttcaa
    14761 aggctccaaa cgctattcta taagcgagaa actaaaatct aagtgtctat aagatattga
    14821 aagccttttc ggtaaagtgt atactaaaga agtaaagaaa aatctgcttt agcagaaaat
    14881 aaaaataata ggagaaaatc tatgtcagat ttgaaaaaat acgaaggtgt cattccagcc
    14941 ttctacgcat gttatgatga gcaaggagaa gtaagtccag agcgtacgcg tgccttggtt
    15001 caatacttca ttgataaagg tgttcaaggt ctttatgtca atggttcttc tggtgaatgt
    15061 atctaccaaa gcgttgaaga tcgcaagttg attttggaag aagtcatggc ggtagccaaa
    15121 ggtaaattga ccattattgc ccatgttgct tgcaataata ctaaagatag tatggaactt
    15181 gctcgccatg ctgaaagctt gggagtagat gctattgcaa cgattccacc aatttacttc
    15241 cgcttgccag aatactcagt tgctaaatac tggaacgata ttagttctgc agctccaaat
    15301 acagactacg tgatttataa cattcctcaa ttggcaggtg ttgctttgac tccaagcctt
    15361 tacactgaaa tgttgaaaaa tcctcgtgtt atcggtgtga agaactcttc tatgccagtt
    15421 caagatatcc aaacctttgt gagccttggt ggggaagacc atatcgtctt taacggtcca
    15481 gatgaacagt tcctaggtgg tcgcctcatg ggtgccaaag ctggtatcgg tggtacttat
    15541 ggtgctatgc cagaactctt cttgaaactc aaccaattga ttgcggataa agatttagaa
    15601 acagcgcgtg agttacagta tgctatcaac gctatcattg gtaaattgac tgctacacat
    15661 ggaaatatgt acggtgtcat caaagaagtt ttgaagatca atgaaggctt gaatattggt
    15721 tctgttcgtt caccattgac accagtgact gaagaagatc gtccagttgt agaagcggct
    15781 gctgccttga ttcgtgaaac caaggagcgc ttcctctaat ctaaaaggag gtatttatga
    15841 catactacgt tgcaattgat atcggtggaa ccaacatcaa gtatggtttg gttgatcaag
    15901 aggggcaact tcttgaatcg catgaaatgc caactgaggc gcataagggt ggacctcata
    15961 tcttacaaaa gaccaaagat atcgtagcta gttatttaga aaaaggccca gtagcaggtg
    16021 ttgccatatc ttctgctggg atggtggatc cggataaggg tgagattttc tatgctgggc
    16081 cgcaaatccc taactacgca ggcacccagt tcaaaaagga aatcgaagaa agctttacta
    16141 ttccttgtga gattgaaaat gatgtcaact gtgcaggtct tgctgaggca gtatctggtt
    16201 caggcaaggg agcaagtgtg acactttgct tgaccattgg aacaggtatc ggtggttgct
    16261 tgattatgga taggaaagtc ttccatggtt ttagcaattc agcctgtgaa gtcgggtata
    16321 tgcatatgca ggatggagct tttcaagact tggcttctac aacagcttta gtgaaatatg
    16381 tagctgaagc ccatggagaa gatgttgatc agtggaatgg ccgacgtatc tttcaggaag
    16441 ctactgaagg aaacaaaatc tgcatggaag gcattgaccg tatggttgac tatctaggaa
    16501 aaggtctggc aaatatttgc tacgttgcca atccagaagt ggtcattctt ggtggaggta
    16561 tcatggggca agaggctatc ctcaaaccta agatccgcac agccttgaaa gaggctttgg
    16621 taccaagttt agcagaaaaa acacgattag aatttgccca tcaccaaaat acagcaggga
    16681 tgttgggtgc atattatcat tttaagacaa aacaatccta gtttggctca gccaaactag
    16741 gattttctta cacgtttttg tctacgatag ccgttgagtt ttttattttc ccagtagcta
    16801 ttaaagattt tttccttgct ttcgcgattg atttccaaaa agtaggcata aatcaaatcg
    16861 ataaagaaga gcataggaag ttgagcggat attcgttgga tataggaggg ttggctgtgg
    16921 gtggctacaa gaacagtctc tgtataggtc tggctatctt tattgggaac acttgtaaag
    16981 agtacagtct ttgcccccat ctccttggca tctaatagac tatctaaaat agaaggagtt
    17041 gagcctgaaa gtgagaagcc cagtactaga caattttcat ccatgatgct ggttgtccag
    17101 gcaaagccgt cttggtctgt caaagcttcg cagaccacac ctagtcgcat aaaacgtaat
    17161 ttcatttcac gggcgacgag gccagaactc cctgttccaa agaagtagat acgctcagca
    17221 tcttcgatta gctgggcaat tcgctctagt tggatttcgt caatcaagtc ttgtgtttgt
    17281 tccctcatat tgctataact tctgaggact cgtttggtca gtggactgtg cttggagact
    17341 tggttggctt gattttctgc ctgatgttgg tattggaaaa taaattctcg gtagccggta
    17401 aagccacact ttttagcaaa gcgggtcaaa gcagcttgag aaatatgtaa tttttgggtg
    17461 acttgttgag aagataaatc atctgtaatc gtttcagctt gcaaaaaata gcgagcgatt
    17521 tcttgctcta ggtctgtcat ttcttcaaaa tgggaatcaa tgacagttgc gatatctggt
    17581 ttgtccatgg gaaaggctcc tttaaatgag tcgtattgga aaaaggctag attattgaac
    17641 tcttacattt attatatcat ataatatagg gatgaataaa taaaaacgta tcttaccgta
    17701 aaaaggaaaa aagcttcttt cttttccata attttctgtt caaattgtgg tacaattaag
    17761 agtaagattt taagttagaa acgagactga tttgtatgag aaaatttaac agccattcga
    17821 ttccgattcg gcttaattta ttgttttcaa tcgtcatttt actctttatg accattattg
    17881 gtcgtttgtt gtatatgcag gttttgaaca aggattttta cgaaaaaaag ctagcctcag
    17941 ctagtcagac caaggtcaca agcagttctg cccgtgggga aatttatgat gctagtggaa
    18001 aacctttggt agaaaatacg ttaaagcagg ttgtttcctt tacgcgtagc aataaaatga
    18061 cggctacaga cttaaaagaa atagctaaaa agttactgac ttatgtgagc atcagctctc
    18121 ctaatttgac agaacgccag ctggctgatt actatttgtc tgatcctgaa atctataaaa
    18181 aaacagtgga ggctctccca agtgagaaac gcttggattc agatggcaat cgcctatccg
    18241 aatcagaact gtataacaat gcggtcgata gtgtcccaac aagtcaacta aactatacag
    18301 aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa tgctgttgga aactttgcga
    18361 caggaaccat tgcgacagat cctctaaatg attctcaggt ggctgtcatt gcctctattt
    18421 caaaggagat gcctggcatt agtatttcta cttcttggga tcgaaagatt ttggaaactt
    18481 ccctttcttc tatagtaggg agtgtatcca gtgaaaaagc tggtctccca gcggaagaag
    18541 cagaagccta tcttaaaaaa ggctattctc taaatgaccg tgttggaacc tcgtatttgg
    18601 aaaagcaata tgaagagacc ttacaaggaa aacgctcggt aaaagaaatc catctggata
    18661 aatatggcaa tatggaaagc gtggatacaa ttgaggaagg tagtaaggga aacaatatca
    18721 aactgaccat tgatttggcc ttccaagata gcgtggatgc tttgctgaaa agttatttca
    18781 attccgagct aggaaatggt ggagccaagt attctgaggg tgtgtatgca gtcgccctta
    18841 accccaaaac aggtgctgtt ttgtctatgt caggactcaa acatgacctg aaaacgggag
    18901 agttgactcc tgattccttg ggaacggtaa ccaatgtctt tgtcccaggt tcggttgtta
    18961 aggccgctac catcagctca ggttgggaaa atggtgtttt atcaggaaac caaaccttaa
    19021 cagatcagcc tattgttttc caaggttcag ctccaattta ttcttggtat aaattggcat
    19081 atggatcttt tcctattaca gctgtggaag ccttggagta ttcatccaat gcttacatgg
    19141 ttcaaaccgc tcttggaatc atgggccaga cctatcaacc aaatatgttt gttggaacca
    19201 gcaatttgga aacagctatg ggaaaacttc gtgcgacctt tggcgaatat ggcttggggg
    19261 ctgcgaccgg aattgaccta ccagatgaat ctactggatt tgttcccaaa gagtatagct
    19321 ttgctaatta catcaccaat tcctttgggc agtttgataa ctatacgccc atgcagttgg
    19381 ctcagtatgt agcaactatt gcaaatgatg gtgttcgtgt ggctcctcgt attgttgaag
    19441 gcatttatgg taataatgat aagggaggac tgggtgactt gattcagcaa ctgcaaccga
    19501 cagagatgaa taaggtcaat atatccgact ccgatatgag tatcttgcac caaggttttt
    19561 atcaggttgc tcatgggact agcggcttga caactggacg tgccttttca aatggtgcct
    19621 tggtatccat tagcggaaaa acgggtacag ccgaaagcta tgtggcagat ggtcagcaag
    19681 caaccaatac caatgcggtg gcctatgccc catctgataa tccccaaatc gctgttgcag
    19741 tggtctttcc tcataatacc aatctaacaa atggtgtagg accttccatt gcgcgtgaca
    19801 ttatcaatct gtatcaaaaa taccatccaa tgaattagaa aggaaattat gctttatcca
    19861 acacccattg ccaagctgat tgacagttat tccaagttac caggtatcgg gattaagacg
    19921 gctacgcgtc tggcctttta tacgattggg atgtctgatg atgatgtcaa tgaatttgca
    19981 aaaaatctcc tttctgctaa gagagaattg acctactgtt ccatttgtgg acgtttgaca
    20041 gacgacgatc cttgttctat ctgtaccgat ccgactcgtg accagacaac gattttggtg
    20101 ctagaggata gtcgtgatgt ggcggccatg gaaaatatcc aagaatacca tggcctctat
    20161 catgttctgc atggcctcat ttctcctatg aatggcatta gtccagacga tatcaatctc
    20221 aagagtctca tgactcgtct tatggatagt gaggtttcag aagtaatcgt agcaaccaat
    20281 gccacagcag atggggaagc gacttccatg tatctttcac gtttgctcaa gccagctggc
    20341 atcaaggtta cgcgcctggc gcgaggcctc gctgtgggag cagatatcga gtatgcggac
    20401 gaagtgaccc tcttacgggc tattgaaaat cgaacagagt tgtaagtgta gacaaattta
    20461 cgaactctat tcatttataa aaaatcaaag aggctgaaaa tcgttcctat cggcctcttt
    20521 ttgtatagtg tgatgggtag gttcaggttc aagttttaaa aaaacaagca aatgtgatat
    20581 actaaagagc gagtattcta gtagaattag gacaagtaat atgaaacaaa cgattattct
    20641 tttatatggt ggacggagtg cggaacgcga agtctctgtc ctttcagcgg aaagtgtcat
    20701 gcgtgcggtt aactacgacc gtttcacagt taagactttc tttatcagtc agtcaggtga
    20761 ttttatcaaa acgcaggaat ttagtcagac tccaggtcaa gaggaccgtc tcatgaccaa
    20821 tgcgaccatt gattgggata agaaagtttc accaagtgcc atctacgaag aaggtgcggt
    20881 agtctttccg gttcttcacg gtccgatggg ggaggatggc tctgttcaag gattcttgga
    20941 agttttgaaa atgccttatg tcggctgtaa tatcttgtca tcaagtcttg ccatggataa
    21001 aatcacgacc aagcgtgtgt tagaatctgc aggcattgcc caagttcctt atgtggctat
    21061 cgttgaaggg gatgatgtga ctgctaaaat cgctgaagtg gaagaaaaat tggcttatcc
    21121 agtcttcact aagccgtcaa acatgggttc tagtgtcggt atttctaaat ctgaaaacca
    21181 agaggaactc cgtcaagctt tgaaacttgc cttccaatat gacagccgtg tcttggttga
    21241 gcaaggggtg aatgcccgtg aaatcgaggt tggactcttg ggaaattacg atgtcaagag
    21301 cacgcttcca ggagaagtag tcaaggatgt tgccttttat gactacgatg ccaagtatat
    21361 tgataacaag attactatgg atattcctgc caaaatcagt gatgatgtgg tagctgtcat
    21421 gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc ctcggtctct ctcgttgcga
    21481 tttcttctat acagataagg aagagatttt cctaaacgag ctgaatacca tgccaggctt
    21541 cacccagtgg tctatgtatc cactactttg ggataatatg ggaatcagct acccagacct
    21601 aatcgagcat ttggttgccc ttgctaagga aagttttgat aagcgcgaag cgcatttgct
    21661 ataaaaatga aagagagggt agaagccaga actatcactg caaggtgatc agagttctcg
    21721 gacttcaacc ctttttaaag gagtagaaat gaaattaaca atccatgagg ttgcccaagc
    21781 tgttggagct aaaaatgata tcagtatctt tgaggacacc cagttagaaa aagctgagtt
    21841 tgatagtcgt ttgattggaa ctggagattt atttgtgcca cttaaaggtg cgcgtgatgg
    21901 ccatgacttt attgaaacag cctttgaaaa tggtgcagca gtaaccttgt ctgagaaaga
    21961 ggtctcaaat catccttaca ttctagtaga tgatgttttg acagcctttc aatccttagc
    22021 atcctactat cttgaaaaaa cgactgttga tgtctttgct gttacaggtt caaatggcaa
    22081 gacaacgact aaggatatgt tggcgcattt actgtcaaca agatacaaga cctacaaaac
    22141 acaaggcaat tacaataatg agattggcct tccttacaca gttcttcata tgcctgaagg
    22201 aacagaaaag ttggttttgg agatgggaca ggatcacttg ggcgatattc atctcttgtc
    22261 tgaattggct cgtccaaaaa cagtcatcgt gaccttggtt ggagaagccc atttggcctt
    22321 tttcaaagac cgttcagaga ttgctaaggg aaaaatgcaa attgcagacg gaatggcttc
    22381 aggttccttg cttttagcgc cggctgaccc tatcgtagag gactatttgc caactgataa
    22441 aaaggtggtt cgttttgggc aaggggcaga gctggaaatt actgacttgg ttgagcgcaa
    22501 agatagtctg accttcaagg ccaatttctt agagcaagcc cttgatttgc cagtaactgg
    22561 caagtacaat gcgacaaatg ctatgattgc atcctatgtt gccttgcaag aaggagtttc
    22621 agaggagcaa attcgtttgg ccttccaaga tcttgaattg acgcgtaacc gtaccgagtg
    22681 gaagaaagca gccaatggag cagatatcct gtcagatgtt tacaatgcca atccaactgc
    22741 tatgaaactg attttagaga ccttctctgc cattccagcc aatgaaggtg gcaagaaaat
    22801 tgcagtgttg gcggatatga aggagcttgg tgaccagtct gttcaacttc ataatcagat
    22861 gattttgagc ctttctccag atgtgcttga taccgtgatt ttctatggac aagatattgc
    22921 tcagttggct caattggcca gtcaaatgtt cccaatcggc cacgtttact acttcaagaa
    22981 aacagaagac caggatcaat ttgaagacct agtcaagcag gttaaggaaa gccttggagc
    23041 ctatgaccaa atcttgctaa aaggttctaa ctctatgaat ctagccaaat tggtagaaag
    23101 tttagaaaat gaagccaagt gattttgtta agtatctgca aagaatgatt gcccttacag
    23161 atactggctt aacctttaca aaagatcctt ttgaccgtga gcgctacgag gacttgcgaa
    23221 gtctgttatc tgaaatgttg aatcagggat cagacctgga tgtagaagaa gtagcagaag
    23281 tcttgaaacc aacttcagct tatgcgactc ccttaatgga cgtccgtgct tggattgttg
    23341 aggatgagaa gatttgtctg gttaggggac aaggagagga tagttgggct ttgccaggtg
    23401 gctttggtga agtcggctat tctccaactg aaaatattct caaggaaatt gaagaagaaa
    23461 ccggttttaa agccaaagtt gaaagactgc tagctgtttt tgataccaat cgtttccaac
    23521 tacagagcaa acaatatgca aagtttgttt ttgaatgtaa gcttctcgat ggacaattcc
    23581 aagaaaatca agaaatcgct gaccttcaat tttttgcaat tgaccaactg ccgaatttat
    23641 ctgaaaaacg cattaccaag gagcaaatcg agattctttg gcaggtttat caaggtcaga
    23701 gggagcaata tcttgactaa gaagatgatt atcgtatttc taaattcatt tttcttaagt
    23761 agcatggtat aataaaatgc aggaaaattt tgaatcatga ggaagactag atgaatttat
    23821 gggatatttt ctttacgact caggcaaccg agccgcccaa atttgacctt ttttggtatg
    23881 ttagcctatt tacgctctta gccttaacct tttatacagc ccatcgctat cgtgaaaaga
    23941 aggtttacca acgatttttc caaatcttgc agactgttca gttaatcctt ctttatggtt
    24001 ggtactgggt caatcatatg ccactgtcag aaagcctacc cttttaccat tgccgtatgg
    24061 ctatgtttgt ggtactcttg cttcctggtc agtccaaata taaacaatac tttgcattat
    24121 tgggaacatt tgggacatta gcagcctttg tttatccagt gccagatgct tacccttttc
    24181 cacatatcac cattctatcc tttatctttg gtcatttagc actcttgggg aactctctag
    24241 tttatctatt gagacagtat aatgcgcgat tgctggatgt gaagggaatt tttctcatga
    24301 cctttgccct aaatgccttg atttttgtgg tcaatttggt gacaggtggc gattacggat
    24361 ttttgacaaa accgccattg gttggggatc acggtctagt agctaattat ttacttgttt
    24421 caattgtgct ggtagctact atcagtttga ctaagaaaat cttagaattc tttttagctc
    24481 aagaagcaga aaaaatgatt gcaaaggaag cttaacacag agctttcttt tttgctctta
    24541 gagagttttt acaagcagct tataaaataa gaatttctga atagacaaac tcaaaaaatg
    24601 gctgggaaat ttaggaaaaa agcaagcacg attaaatttt ttgtgttata atattttgtg
    24661 aatagctatg cctatgttta gctatggaat aatacgaagt gcgaaacttg gaagatagag
    24721 aggaagcgat gtaatggcta gagaaggctt ttttacaggt ctagatattg gaacaagctc
    24781 tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa
    24841 tgccaaaagt aaaggtgtaa aggatggaat tattgttgat attgatgcag cagcaactgc
    24901 tatcaagtca gccatttccc aagcggaaga aaaggcaggc atttcgatta aatcagtgaa
    24961 tgtcggcttg cctggtaatc ttttgcaggt agaaccaact caggggatga ttccagtaac
    25021 atctgatact aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat cagctttgac
    25081 aaagagtatg acacctgacc gtgaagtcat tacctttatt cctgaagaat ttattgtgga
    25141 tggtttccaa gggattcgtg acccacgtgg catgatgggg gttcgccttg aaatgcgtgg
    25201 tttgctttat acaggacctc gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc
    25261 aggtgttcag gttgaaaatg ttatcatttc accactagca atggttcagt ctgttttgaa
    25321 cgaaggggaa cgtgaatttg gtgctacagt gattgatatg ggggcaggtc aaacgactgt
    25381 cgctacaatc cgtaatcaag aactccagtt cacacatatt ctccaagaag gtggagatta
    25441 tgtaactaaa gatatctcca aggttttgaa aacctctcgc aaattagcgg aaggcttgaa
    25501 actgaattac ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt
    25561 tattggagaa gtagaagcag tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc
    25621 acgaatcaag cacatccttg aacaaatcaa gcaagaatta gatagaaggc gtctattgga
    25681 cctccctggt ggtattgtct taatcggtgg gaatgccatt ttaccaggta tggttgagct
    25741 tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg
    25801 taatccagcc tttgcgcatg tgattagttt atcagaattt gcgggtcaat taacagaagt
    25861 taatcttttg gctcagggag cgataaaagg tgagaatgac ttaagtcatc agccaattag
    25921 ttttggtggg atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc
    25981 tcctgctcca gaagtagagc cggtggcgcc tacagaacca atggcggatt tccaacaagc
    26041 ttcacaaaat aaaccgaaat tagcagatcg tttccgtgga ttgatcggaa gcatgtttga
    26101 cgaataaaga ggaaaaataa attatgacat tttcatttga tacagctgct gctcaagggg
    26161 cagtgattaa agtaattggt gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg
    26221 acgaaggtgt tacaggcgta gaatttatcg cagcaaacac agatgtacaa gcattgagta
    26281 gtacaaaagc tgagactgtt attcagttgg gacctaaatt gactcgtggt ttgggtgcag
    26341 gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag
    26401 ctattagtgg tgccgatatg gtcttcatca ctgctggtat gggaggaggc tctggaactg
    26461 gagctgctcc tgttattgct cgtatcgcca aagatttagg tgcgcttaca gttggtgttg
    26521 taacacgtcc ctttggtttt gaaggaagta agcgtggaca atttgctgta gaaggaatca
    26581 atcaacttcg tgagcatgta gacactctat tgattatctc aaacaacaat ttgcttgaaa
    26641 ttgttgataa gaaaacaccg cttttggagg ctcttagcga agcggataac gttcttcgtc
    26701 aaggtgttca agggattacc gatttgatta ccaatccagg attgattaac cttgactttg
    26761 ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct tatgggtatt ggtatcggta
    26821 gtggagaaga acgtgtggta gaagcggcac gtaaggcaat ctattcacca cttcttgaaa
    26881 caactattga cggtgctgag gatgttatcg tcaacgttac tggtggtctt gacttaacct
    26941 tgattgaggc agaagaggct tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca
    27001 tctggctcgg tacttcaatt gatgaaagta tgcgtgatga aattcgtgta acagttgttg
    27061 caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct agatctgcta
    27121 ctaactaccg tgagacagtg aaaccagctc attcacatgg ctttgatcgt cattttgata
    27181 tggcagaaac agttgaattg ccaaaacaaa atccacgtcg tttggaacca actcaggtat
    27241 ctgcttttgg tgattgggat cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg
    27301 tttctccagt cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa ttggatacac
    27361 ctccattttt caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga acttgttttt
    27421 cgagaagttg cagaggctag tctgagtgct catcgagaga gtggttcggt ctctgtcatt
    27481 gcagttacca agtatgtaga tgtaccgaca gcggaagcct tgcttccgct aggtgttcat
    27541 catatcggtg aaaatcgtgt agataagttt ctggaaaaat atgaagcttt aaaagatcga
    27601 gatgtgactt ggcatttgat tggtaccttg caaagacgta aggtgaaaga tatcattcaa
    27661 tacgttgatt atttccatgc attggactca gtaaagctag caggggaaat tcaaaaaaga
    27721 agtgaccgag tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga aagcaaacac
    27781 ggtttttcga gagaggaact gctggaaatc ttgccagagt tagccagact agataagatt
    27841 gaatatgttg gtttaatgac gatggcacct tttgaggcta gcagtgagca gttgaaagag
    27901 attttcaagg cgacccaaga tttacaaaga gaaattcaag agaaacaaat tccaaatatg
    27961 cctatgaccg agttaagtat gggaatgagt cgtgattata aagaagcgat tcaattcggt
    28021 tccacttttg ttcgtatagg tacatcattt tttaagtagg agagaaccat gtctttaaaa
    28081 gatagattcg atagatttat agattatttt acggaggatg aggattcaag tctcccttat
    28141 gaaaaaagag atgagcctgt gtttactcca gtaaattctt cacaggaacc ggctctccca
    28201 atgaatcaac cttcacagtc ggctggtaca aaagagaaca atatcaccag acttcatgca
    28261 agacaacagg aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt
    28321 cgttatccta gaaaatatga ggatgcaaca gaaattgttg atttattggc aggaaacgaa
    28381 agtatcttga ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg tttggactat
    28441 ttggatggag cttgtcatgt tttagctgga aatttgaaaa aggtagcttc taccatgtat
    28501 ttgttgacac cagtgaacgt tattgtaaat gttgaagata tccgtttacc agatgaagat
    28561 caacagggtg agttcggttt tgatatgaag cgaaatagag tacgataatg atttttttaa
    28621 ttcgtatgat ttataatgca gtggatattt actccctgat tttggtagcc ttcgctgtca
    28681 tgtcttggtt tccaggtgcc tatgaatcca gtttaggtcg ttggattgta gcgttggtaa
    28741 aaccagtgct tgctcccttg caacgcctgc ctttacagat agcgggtctt gatttatctg
    28801 tttgggttgc gattgttttg gttcgatttt taggagaaaa cctagtgcgt tttctggcga
    28861 tgataggatg aataaaggga tttatcagca tttctccata gaagatcgtc catttcttga
    28921 caagggaatg gaatggataa agaaggtaga agatagctat gctccttttt taactccttt
    28981 tatcaatcct catcaggaga agctattaaa gattttggcc aaaacctatg gtcttgcttg
    29041 tagcagtagt ggggaatttg tctcgagtga gtatgttcga gttttattat acccagatta
    29101 tttccaacca gagttttcag attttgaaat atctcttcag gaaattgtgt attccaataa
    29161 atttgaacat ttaacgcatg ctaagatttt agggacagtc atcaatcaat tagggattga
    29221 acggaaactt tttggagata tcctagtaga tgaagagcgg gcgcagatta tgattaatca
    29281 gcagtttctt cttctctttc aagatggatt aaagaaaatt ggtcgtatac ctgtttcgct
    29341 ggaggaacgt cctctcgccg agaaaataga taagctagaa cagtatcgag aactggattt
    29401 atctgtgtct agttttcgat tagatgttct tttatcaaat gttttgaaac tatctaggaa
    29461 tcaagcaaac cagttgattg aaaagaaact tgtccaagta aattatcatg tggtagacaa
    29521 atcagattat actgttcaag ttggagattt gattagtgtg agaaaatttg gtcgcttgaa
    29581 attacttcaa gataagggac aaacgaaaaa agagaagaaa aaaataaccg tccagttatt
    29641 attaagtaag tgaggaatag aatgccaatt acatcattag aaataaagga caaaaccttt
    29701 ggaactcgat tcagaggttt tgatccagaa gaagtcgatg aatttttaga tattgtggtt
    29761 cgtgattacg aagatcttgt tcgtgcaaat catgataaag atttgcgtat taagagttta
    29821 gaagagcgtt tgtcttactt tgacgaaatg aaagattcat tgagccagtc tgtattaatt
    29881 gcccaggata cagcggagag agtgaaacag gcagcgcatg aacgttcaaa taatatcatt
    29941 catcaagcag agcaagatgc ccagcgcttg ttggaagaag ctaagtacaa ggcaaacgag
    30001 attcttcgtc aagcaactga taatgctaag aaagttgctg ttgaaacaga agaattgaag
    30061 aacaagagcc gtgtcttcca ccaacgtctc aaatctacaa ttgagagtca gttggctatt
    30121 gttgaatctt cagattggga agatattctt cgcccaacag ctatttatct tcaaaccagt
    30181 gatgaagcct ttaaagaagt ggttagcgag gtcttgggtg agtctgtgtt acagcaacat
    30241 ccagaggaag aaccaattga tatgacacgt cagttctctc aagtagaaat ggcagaatta
    30301 caggctcgta ttgaggcagc caataaagaa ttggctgaat ttgaagctca gactaaacag
    30361 gaagtggaag ctccaactcc tgtagtgagt cctcaaattg aagaagaacc tactcaacca
    30421 gttggtccaa tgtatgaaga accagaagta gctccagtat atccttcagc ttcaacacca
    30481 gctacagaaa ctgttgattc agcaccagga tttgaagcac cgcaagaatc tgttacaatt
    30541 ttataagaaa tattctgaga acaatatctt atccttatat ttccagcgag caggagatgg
    30601 tgtgagtcct gtaatcccta acgataagat tatcctctca aaaactcaag tctgaagtta
    30661 gtaggatttg acgttcccca cgttacggga taagagggag aaagactaga tctttttccg
    30721 aataaaggtg gtaccacgat tttcgtcctt tttggaagtc gtggttttta atttgttatt
    30781 atttataaag gagataccat gaaactcaaa gataccctta atcttgggaa aacagctttt
    30841 ccaatgcgtg caggccttcc taccaaagag ccagtttggc aaaaggaatg ggaagatgca
    30901 aaactttatc aacgtcgtca agaactaaat gaagggaaac cgcattttgt cttgcatgat
    30961 ggccctccat acgcaaacgg aaatatccac gttggacatg ccatgaatca tatctcaaaa
    31021 gatatcatca ttcgttctaa gtctatgtca ggttttaact caccttatat cccgggttgg
    31081 gatactcatg gtctgccaat cgagcaagtt ttggcaaagc aaggtgttaa gcgcaaagaa
    31141 atggacttgg ttgagtactt gaaactttgt cgtgagtacg ctctttctca agtttataaa
    31201 caacgtgatg atttcaagcg cttggggatg tcaggtgact gggaaaattt atatgtgact
    31261 ttaactccag actacgaagc agcccaaatc cgtgtatttg gtgagatggc taataaaggc
    31321 tatatctacc gtggtgcaaa accagtttac tggtcttggt catctgagtc agcccttgct
    31381 gaagcggaaa ttgaatacca tgatttggtt tcaacttccc tttactatgc caataaggta
    31441 aaagatggca aaggtgttct agatacagat acttatatcg ttgtttggac aactactcca
    31501 tttactatta cagcttctcg tggtttgact gttggtgcag atattgatta cgttttggtt
    31561 caacctgctg gtgaaactcg taagtttgtg gttgctgcag aattgttgat tagcttgtct
    31621 gagaaatttg gttgggctga tgttcaagtg ttggcaactt accgtggtca agaactcaac
    31681 cacatcgtaa cagaacaccc atgggataca gttgtagatg agttggttat ccttggtgac
    31741 cacgttacaa ctgactctgg tactggtatt gtccatacag cccctggttt tggtgaggat
    31801 gactacaatg ttggtattgc taatggtctt gaagtcgcag tgactgttga cgaacgtggt
    31861 atcatgatga agaatgctgg tcctgagttt gaaggtcaat tctatgaaaa ggtggttcca
    31921 actgttattg aaaaacttgg taacctcctt cttgctcaag aagaaatctc tcactcatac
    31981 ccatttgact ggcgtaccaa gaaaccaatt atctggcgtg cagtaccaca gtggttcgcc
    32041 tctgtttcaa aattccgcca agaaatcttg gatgctattg ataaagttaa attccataca
    32101 gaatggggga aagtacgtct atataatatg attcgtgacc gtggtgactg ggttatctct
    32161 cgtcaacgtg cttggggtgt tccacttcca atcttctatg cagaagacgg tacagctatc
    32221 atgacagctg aaacgattga acacgtagct caactctttg aagtacatgg ttcaagcatt
    32281 tggtgggaac gtgataccaa agacctcttg ccagaaggat ttacacatcc aggttctcca
    32341 aatggggagt tcaagaaaga aacagatatt atggatgtat ggtttgactc aggttcatca
    32401 tggaatggtg ttttggtaaa tcgtccaaat ctgacttatc cagctgacct ttaccttgaa
    32461 ggttctgacc aataccgtgg ttggttcaac tcatcactca ttacatctgt tgccaaccat
    32521 ggcgtagcac cttacaaaca aatcttgtca caaggttttg cccttgatgg taaaggtgag
    32581 aagatgtcta aatctcttgg aaataccatt gctccaagcg atgttgaaaa acaatttggt
    32641 gctgaaatct tgcgtctctg ggtaacaagt gttgactcaa gcaacgacgt acgtatctct
    32701 atggatatct tgagccaagt ctctgaaact taccgtaaaa tccgtaacac ccttcgtttc
    32761 ttgattgcca atacatctga ctttaaccca gctcaagacg cagtagcata cgaagagctt
    32821 cgctcagttg ataagtacat gactattcgc tttaaccagc ttgtcaagac cattcgtgat
    32881 gcttacgcaa actttgaatt cttgacaatc tacaaggcct tggtgaactt tatcaacgtt
    32941 gacttgtcag ccttttacct tgattttgct aaggacgttg tttacatcga aggtgctaaa
    33001 tcattggaac gccgtcaaat gcagactgtc ttctatgaca ttcttgtgaa aatcacgaaa
    33061 ctcttgactc caatccttcc tcacactgcg gaagaaatct ggtcatatct tgagtttgaa
    33121 gccgaagact tcgttcaatt gtcagaattg ccagaagcgg aaacttttgc taatcaagaa
    33181 gaaatcttgg atacatgggc agccttcatg gacttccgtg gacaagctca aaaagccttg
    33241 gaagaagctc gtaatgcaaa agtaatcggt aaatcacttg aagcacactt gacagtttat
    33301 ccaaacgaag ttgtgaaaac tctactcgaa gcagtaaaca gcaatgtggc ccaacttttg
    33361 atcgtgtctg agttgaccat ggcagaggga ccagctccgg aagctgccct tagcttcgaa
    33421 gatgtagcct tcacagttga acgtgctgct ggtgaagtat gtgaccgttg ccgtcgtatc
    33481 gacccaacaa cagcagaacg cagctaccag gcagttatct gtgaccactg tgcaagcatc
    33541 gtagaagaaa attttgcgga agcagtcgca ggaggatttg aagagaaata agatgaaaag
    33601 tctctatgcg tctagtatat aaaaatgagt tattccaagt ttataatctc tcttgtgaga
    33661 tgctaaagtt tgatgagaat tggttttgct aatattagga gaaagtaagt atgctaaaat
    33721 tgcaagattg tttttcttgc gattgtttaa actagtgagg aaaaataaac attatgagac
    33781 aaacaaatgt tagaggaagc ttgtccctcc gtggctttag aaaattaaga actggtgcaa
    33841 ttgttgcgac aggtgtgatt ctactggggc tgggcttttc agctccaact gcgtcagtca
    33901 gtgaacaaga tggtgtttgg gtagccagaa cagttgcaga agtaaaagct gatattcaaa
    33961 aagaaggtga tttatttaag tatgtcatta agtggggaga tacattaagt gttatcagcg
    34021 aagcaagcaa tatccctgta gatgtactcc aagaaatgaa tcaagcttca ggcaagaatt
    34081 tattcttacc atacaatgaa ttgtacttta ctgaagctga aacagtttca gatacagtca
    34141 caaaacacaa gattgtcatc aaagaaagtg gtgcaagtgg cgaagttcgc acttatgagg
    34201 tcttgctcaa gaaagaccaa gaaacaaaag ctgttacctt tgaattaaca gatgtcactg
    34261 agaaagttga aaaaatgact gtgaactata gcccagttta tcagcctgta tcagtaccag
    34321 tagtggaaag agcggaagaa tcagttgaag agcctgccct agtagcacca gctgtgacaa
    34381 gcccagaagt taaagaagaa acagaagatc cagtagtact aaaagcagaa gaagcagcga
    34441 ctaccccagc aacgaaagaa acagcaccag aggtggtaac accagctgaa ccaaacgcag
    34501 aaaccccagc gccgaaagta gaagcgccaa cagaatcatc tgaaccaaaa ggaacagagc
    34561 cagaggtagc caaaccagct ggagattcag tatcatctac aagtgagtca aatgaggatg
    34621 gcaattcagg cgattcaact cattcaacat tgacctctga tgaaacaaaa ccagaagagg
    34681 tagaatcaac ttcagtaacg gacaatgtcc cttcaaatgc agggacaaca aatcaacctc
    34741 taaccccaac atctaattct gatgattcag caccaaaaga agtagcaaat ggaactgaag
    34801 gaaaagtaga agcgccgaaa gttgaagaag cagtatcaga aggagaagaa ggtaacgccg
    34861 aaataacaaa taatccatca acaggcgcta ctccttcaag tgatgaaacg acagaacaat
    34921 ctggaactcc agctccaaaa ccagaagagg aagctccagt agcgacagaa acctcagcgg
    34981 catcagctga atcaacagaa tcagcaccag tggtagcaaa accagctgag ccaaaagcag
    35041 aaacaccaga agcaacaatt acaggagatg aaggaaaaga atctgaagaa tcaggaacat
    35101 ctgcaactgt ggaatcaaca ccagcaggag aagaaggaaa agcggaggat tcagtttctt
    35161 caactgaatc ttcatcaact gcttctgaag gggagtcaac agctacgcaa ccagctgtag
    35221 aagcaggaac agattcaaca tcggaagctg aagaacttgc aactacggaa acagcaacaa
    35281 cgccgaaaac ggaagagcca gaagcggtag ccccagctcc agaagcaccc tcagaatcag
    35341 actcgaaaga agaagattca gctgcagggg atacaacagt tacagaagaa cagccagctg
    35401 cagaaactgt ctctgaaggt ggatcaccag ctacgcaacc ggctggagaa gaaggtaaat
    35461 ctgaaaaaga accgaaagta gaagggcaac catcaggtac agagtcggca accccagaac
    35521 agcatacaaa tattgaggaa acaacagaaa agcaatcggg ggctacatca gaaaattcag
    35581 gtgatagtct agtatcagat gagccagctg cgagctcagg tatttcaaca tcttcaggaa
    35641 cagaaggggc agaaacgata gatacagaaa caattgcaga aaaatcagaa ataccgtctc
    35701 cagcagaaga aggatctgct aaagaagaaa aagaagttat taagaaacta gaacttagaa
    35761 atatatcttc tgttgaacta tattctaaag aaggtgataa gtatcgtcat gtaacttcac
    35821 ttgctacctt accaagtaat ccagagactt actttatgaa agttaaatca gagaacttta
    35881 aagatgttat gctaccagtt acaagcatta ctaatgataa taaagataat agagatgttt
    35941 ataaaatagt agcaagtgta aagaatctga tacagcatga aaataataaa gtactagaga
    36001 attatacata ctatttatca aaaactcagc aaggtgaaac tggagtatat acatcattta
    36061 aaaatttagt tgatgcgatg aatagagatt cttatggaga gtttcgttta ggtgcaacta
    36121 tggatgctcg tgaagttgaa cttccagatg gtcaagaaag ttatgtgaag aatgtatttc
    36181 acggtagact aataggtcaa aatagtaata agtattatgc tatatataat ttgaaaaagc
    36241 cattatttaa tgctttaagt aatgctagag tacaaaatct ttcactaaaa gatgttaata
    36301 tttccgcaaa ggacgatact gcaacactag cgaaagaagc aaataacaat actcatattg
    36361 ataatgttca ttctgatgga gcgatagccg gggaacgtag cataggagga ttagtatcac
    36421 aagttaataa ttctactatt tctaatagta gctatactgg tagaataact aatacatata
    36481 aaacagttgc tagttatcaa atcggaggtt tagtaggtaa actttctggt ccgaatggtt
    36541 taattgataa atcgatagca tcaatagatt tggcttcaaa cgcaacacga ggtgatcagt
    36601 ctattggtgg aatagctggt tcagtaattg ataatgcagt gataagtagt agttatgctg
    36661 aagggaaatt aaataatgtt caaccttttg caaatgttgg tggagtagtt ggtgaccttt
    36721 gggatccagt aggcggattg gaaaaatctg gtcaactatc taatgtacta agtgatgtta
    36781 atgttacaaa cggtaatgct atcgcgggta aacattttga tcacatgaaa gcaactaatg
    36841 tttatagtaa taaaaataat aaggttgtga acgtagtaca agaaaatgat gaaattttaa
    36901 ctaaggattc tgttgttcaa agaggagaag tattagaaga tgaacaaata aaagagaaaa
    36961 aagctgcttt tgttactaaa aatactgtta aaacagaaga ttttaatttc tcttcaagat
    37021 atgtaactga ctataaaaat cttgagaatg ctgattcgtc aaaagaaaaa gtatataaaa
    37081 atattgaaaa actattacca ttttataata gcgaaacaat agtgaagtat gggaatttag
    37141 tagagacaag tagtaatctt tataataaag aattattgtc agttgttcct atgaaagata
    37201 aagaagtaat tagtgatatt aataaaaata aatcaagcat aaataaatta ttactgtatt
    37261 atgcggataa ttcgtatgag acattaaatg taaattatca aagtgatttt tctaatgtag
    37321 cagagtatag cataggcggt acaaatttaa tttatacacc gaatacatta cttcgcgatt
    37381 acaataatat attagatgga gtattacctg tattagaaac tgtggattat aagtcagacg
    37441 caattagaaa agtattagat gtttctaatg atgttagctt aacggagtta tatttagaag
    37501 aacaattcaa tactactaaa aataatttga gagatagtct aacaaaactg cttactgcag
    37561 atgctgcaat atctgaaaat agtaattcaa taattgataa ttatgtaata gaaaaaatta
    37621 agaataataa agaagcgtta cttctaggat taacatattt agagcgttgg tacaatttca
    37681 aatatggtga aacaaaagcg aaagatttag tgatgtacca cttggatttc tttggtaaat
    37741 caaatagttc agctctagat aatgttattg aactaggtaa atctggattt aataatttat
    37801 tagctaagaa taatgttatt acttataatg tattgttatc gaaaaattat aaaactaata
    37861 atttatttga tgcattagaa aaatatagaa aagtttttgt gccagataaa acaaataacg
    37921 aatggtttaa agaacaaact aaagcttata tagtggaaga aaaatctaca attaaagagg
    37981 taaatgataa acaatcaaaa gcaggtactc cgcaatctat aggggtgtat gatagattaa
    38041 ccagcccatc ttggaaatac ccaagtatgg tattgccgct attaacatta cctgaaaaat
    38101 cggtgtttat catagcgaac atttcaacaa taggatttgg cgcttatgat agatatagaa
    38161 gtaaagaaca tccagcagga actaatttaa atgactatgt tgaggcaaaa gctagagaag
    38221 cggctgttag atttagagat cactatgatt actggtataa aattctagat aataataata
    38281 aagaaaaatt atatagaagt gtcctagtct atgatgcatt tagattcggt gcagatgata
    38341 agggagaaag agaaacaaaa caagctaatt ttgaaactga tcatccagca ataaaacact
    38401 tcttcggtcc agcaggaaat aatgttgttc ataattctaa tggagcatat gctacaggtg
    38461 acgcattcta ctatatggct tatcgtatgc ttgataaaga tggtgcggta acttatacac
    38521 atgaaatgac acataactca gatagagaaa tttatcttgg aggctatgga agacgaaatg
    38581 gacttggacc agagttttat gcaaaaggat tgttacaagc tcctgatcat cctgatgatc
    38641 ctactattac gattaactca atattgaaat atgaagaatc agaagatcca actagacttc
    38701 aggtaaaaga tcctacaaaa cgatttaata atgcagaaga cttgcaaaaa tatatgtata
    38761 atatgtttga tgtaatttat atgctagaat atctagaagg taatgcagtt gttaaattag
    38821 atatttctaa gaaaaatgag ttgttgagaa aaatagaaaa taaatttgaa acagatccag
    38881 atggaagtaa tgtctatgca actaatgttg ttcgttattt aaaacctgaa gagcttacta
    38941 aattaacttc atttaatagt ttaattgaaa atgatgttat tactagaaga ggatacgaaa
    39001 atggaaatga caatactttt aaacgaaatg gatattatac aattaaacta ttttcaccaa
    39061 tatattcagc tttaagtaat aatgaaggaa ctccgggaga tttaatgggt cgtcgtatgg
    39121 catttgaact gttggctgca aaaggattta aagatggaat ggtaccatat atttctaatc
    39181 aatatgcaga agaagcgaaa gctaaaggta aagtgattaa gtcatatggt aaggaagttg
    39241 gtaatgtaac tgatgagtta gtacttcaaa aaatatttaa taatcgttac tcatcttggg
    39301 tagaatttaa aaaagcaatg tataatgaaa gaatagctaa atttaaaaaa ttaatgagca
    39361 ttagcttcga taacccaaat ggaaattggt tcagaaaaga tagagtgaca ataaaaaata
    39421 tagaagatct tcaaagaatg ataactactg ctgtcaatga agatgctgag gattatcttg
    39481 tgaacatata tccagaaaga agtagagttc ttaaactgaa aaaagcaatc tttaaagctt
    39541 atcttgatca aacaaatgat tttagaagtt caatttttga tgaggaaaaa taaatttact
    39601 aattaggggt agcacatgaa gataggtttc gtttcttcat gtgtgaaact ctttcctttt
    39661 tggttttgac tagctttttt gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa
    39721 acctcggaaa atttaaagga gaatccatct aatggtaaaa ttggtttttg ctcgccacgg
    39781 tgagtctgaa tggaataaag ctaacctttt cactggttgg gctgatgttg atttgtctga
    39841 aaaaggtaca caacaagcga ttgacgctgg taaattgatc aaagaagctg gtatcgaatt
    39901 tgaccaagct tacacctcag tattgaaacg tgcgattaaa acaacaaact tggctcttga
    39961 agcttctgac caattgtggg ttccagttga aaaatcatgg cgtttgaacg aacgtcacta
    40021 cggtggtttg actggtaaaa acaaagctga agctgctgag caatttggtg atgagcaagt
    40081 tcacatctgg cgtcgttcat atgatgtatt gcctccaaac atggaccgtg atgatgagca
    40141 ctcagctcac actgatcgtc gttacgcttc acttgacgac tcagttatcc cagatgctga
    40201 aaacttgaaa gtgactttgg aacgtgccct tccattctgg gaagataaaa tcgctccagc
    40261 tcttaaagat ggtaaaaacg tattcgtagg agctcacggt aactcaatcc gtgctcttgt
    40321 aaaacacatc aaaggtttgt cagatgacga gatcatggac gtggaaatcc ctaacttccc
    40381 accattggta ttcgaattcg acgaaaaatt gaacgtagtt tctgaatact accttggaaa
    40441 ataaaaaatt gtaagtctag aattgatttc taggcttttt atgtggctct ttgtcaactg
    40501 tagtgggttg aagtcag
//
LOCUS       DAVFJR010000015        39950 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVFJR010000015 DAVFJR010000000
VERSION     DAVFJR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.016"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            162..617
                     /locus_tag="VU722_001003"
                     /pseudo
     CDS             162..617
                     /locus_tag="VU722_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            770..1066
                     /locus_tag="VU722_001004"
     CDS             770..1066
                     /locus_tag="VU722_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU1772005.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYK"
     gene            1272..3017
                     /locus_tag="VU722_001005"
     CDS             1272..3017
                     /locus_tag="VU722_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772006.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            3007..4758
                     /locus_tag="VU722_001006"
     CDS             3007..4758
                     /locus_tag="VU722_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772007.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            4931..5623
                     /locus_tag="VU722_001007"
     CDS             4931..5623
                     /locus_tag="VU722_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU1772008.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLAFVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            5666..6892
                     /locus_tag="VU722_001008"
     CDS             5666..6892
                     /locus_tag="VU722_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU1772009.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKIVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            8023..10182
                     /gene="pfbA"
                     /locus_tag="VU722_001009"
     CDS             8023..10182
                     /gene="pfbA"
                     /locus_tag="VU722_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU1772010.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNYKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGREAENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            10710..11024
                     /locus_tag="VU722_001010"
                     /pseudo
     CDS             10710..11024
                     /locus_tag="VU722_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            11204..11863
                     /locus_tag="VU722_001011"
     CDS             11204..11863
                     /locus_tag="VU722_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU1772011.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVSYHEKF
                     K"
     gene            11888..12955
                     /locus_tag="VU722_001012"
     CDS             11888..12955
                     /locus_tag="VU722_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1772012.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            13058..14068
                     /locus_tag="VU722_001013"
     CDS             13058..14068
                     /locus_tag="VU722_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772013.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            14080..15771
                     /locus_tag="VU722_001014"
     CDS             14080..15771
                     /locus_tag="VU722_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU1772014.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            15774..16484
                     /locus_tag="VU722_001015"
     CDS             15774..16484
                     /locus_tag="VU722_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU1772015.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            16580..16948
                     /locus_tag="VU722_001016"
     CDS             16580..16948
                     /locus_tag="VU722_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772016.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            17056..18057
                     /locus_tag="VU722_001017"
     CDS             17056..18057
                     /locus_tag="VU722_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1772017.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    18269..18498
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18658..18738
                     /locus_tag="VU722_001018"
                     /pseudo
     CDS             18658..18738
                     /locus_tag="VU722_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            18727..18870
                     /locus_tag="VU722_001019"
     CDS             18727..18870
                     /locus_tag="VU722_001019"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772018.1"
                     /translation="MDRTDEVSSKHCFEVADRTDEVSNHTYDKATLTRFEEFFEEYKG
                     VPR"
     misc_binding    18939..19170
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19242..20603
                     /gene="trpE"
                     /locus_tag="VU722_001020"
     CDS             19242..20603
                     /gene="trpE"
                     /locus_tag="VU722_001020"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU1772019.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDLLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEVLEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVINPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELIAMDALKSTLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            20600..21166
                     /locus_tag="VU722_001021"
     CDS             20600..21166
                     /locus_tag="VU722_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU1772020.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            21177..22181
                     /gene="trpD"
                     /locus_tag="VU722_001022"
     CDS             21177..22181
                     /gene="trpD"
                     /locus_tag="VU722_001022"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU1772021.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            22178..22945
                     /gene="trpC"
                     /locus_tag="VU722_001023"
     CDS             22178..22945
                     /gene="trpC"
                     /locus_tag="VU722_001023"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU1772022.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            22932..23531
                     /locus_tag="VU722_001024"
     CDS             22932..23531
                     /locus_tag="VU722_001024"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU1772023.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSGVKKVGVFVSPSRVELLEVIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            23509..24732
                     /gene="trpB"
                     /locus_tag="VU722_001025"
     CDS             23509..24732
                     /gene="trpB"
                     /locus_tag="VU722_001025"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU1772024.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            24725..25501
                     /locus_tag="VU722_001026"
     CDS             24725..25501
                     /locus_tag="VU722_001026"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU1772025.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVKPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(25473..25574)
                     /locus_tag="VU722_001027"
                     /pseudo
     CDS             complement(25473..25574)
                     /locus_tag="VU722_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            26008..26562
                     /locus_tag="VU722_001028"
     CDS             26008..26562
                     /locus_tag="VU722_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772026.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIIYVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            26577..27728
                     /locus_tag="VU722_001029"
     CDS             26577..27728
                     /locus_tag="VU722_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU1772027.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(27780..28439)
                     /locus_tag="VU722_001030"
     CDS             complement(27780..28439)
                     /locus_tag="VU722_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU1772028.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNHFRCRYCKVRYPVWYALFELGLGLIFLLYSWGWLSLGQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIAYSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASAMGILSFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            28509..28964
                     /locus_tag="VU722_001031"
     CDS             28509..28964
                     /locus_tag="VU722_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772029.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALQDLEGVFSIFDEQEFVELIHKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSL
                     AFENEDIDSISLNVLEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            29004..29276
                     /locus_tag="VU722_001032"
                     /pseudo
     CDS             29004..29276
                     /locus_tag="VU722_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29386..29589)
                     /locus_tag="VU722_001033"
     CDS             complement(29386..29589)
                     /locus_tag="VU722_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU1772030.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGVAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(29620..30228)
                     /locus_tag="VU722_001034"
     CDS             complement(29620..30228)
                     /locus_tag="VU722_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1772031.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEVVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(30259..30429)
                     /locus_tag="VU722_001035"
     CDS             complement(30259..30429)
                     /locus_tag="VU722_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU1772032.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(30441..31007)
                     /gene="amaP"
                     /locus_tag="VU722_001036"
     CDS             complement(30441..31007)
                     /gene="amaP"
                     /locus_tag="VU722_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU1772033.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIQLLSWRQNS
                     AVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVLDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIVDRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(31091..31288)
                     /locus_tag="VU722_001037"
     CDS             complement(31091..31288)
                     /locus_tag="VU722_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU1772034.1"
                     /translation="MAGKITKKGSSMGNIANVFAGLIGASAGQSLLGSWGPSIAGMAL
                     LPFIVGAAIMITVVSFFTGRK"
     gene            31704..33176
                     /locus_tag="VU722_001038"
     CDS             31704..33176
                     /locus_tag="VU722_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1772035.1"
                     /translation="MRDLLSKKSHRQLELLFEHKRWFHRSELAELLNCTERAVKDDLS
                     HVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFSEGCQAES
                     ICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQVIGNERDIRYFFAQYFSEKYY
                     FLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDK
                     DSFNDQSLNALMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDGSLFMK
                     CVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELSTEFILF
                     DQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVIN
                     LLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDI
                     IISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            33492..34748
                     /locus_tag="VU722_001039"
     CDS             33492..34748
                     /locus_tag="VU722_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1772036.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKTSMTDIAHQLAISTSTVIRKLNDFHFECKVRNLPEIMSWDEYA
                     FTKGKMSFIAQDFEKLNIITVLEGRTQAVIRDHFLKYDRAVRCQVKIITMDMFSPYYA
                     LAKQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRY"
     gene            complement(34813..34885)
                     /locus_tag="VU722_001040"
     tRNA            complement(34813..34885)
                     /locus_tag="VU722_001040"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34850..34852),aa:Lys,seq:ctt)
     gene            complement(35150..36421)
                     /locus_tag="VU722_001041"
     CDS             complement(35150..36421)
                     /locus_tag="VU722_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU1772037.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            36719..36934
                     /locus_tag="VU722_001042"
     CDS             36719..36934
                     /locus_tag="VU722_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772038.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDIPKEILD
                     LYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            36924..37172
                     /locus_tag="VU722_001043"
     CDS             36924..37172
                     /locus_tag="VU722_001043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772039.1"
                     /translation="MKNRIIDVFEVVNRILVITVENPDFEDLRVNQFVKIGDKKYRVR
                     SGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH"
     gene            37309..37488
                     /locus_tag="VU722_001044"
     CDS             37309..37488
                     /locus_tag="VU722_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU1772040.1"
                     /translation="MPMTQKEMVKLLTAHGWIKIRGGKGSHIKMEKQGERPITIPHGE
                     LNKYTERGIRKQAGL"
     gene            37525..37977
                     /locus_tag="VU722_001045"
     CDS             37525..37977
                     /locus_tag="VU722_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU1772041.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQT"
     gene            38268..38738
                     /locus_tag="VU722_001046"
     CDS             38268..38738
                     /locus_tag="VU722_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU1772042.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            38757..39824
                     /locus_tag="VU722_001047"
     CDS             38757..39824
                     /locus_tag="VU722_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU1772043.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKELAEGV"
BASE COUNT        12603 a         6842 c         8267 g        12238 t
ORIGIN      
        1 aatcaatatt ccatgagata agtttcataa agttaccttt ttcattcaga ttatagattt
       61 tattatacca aaaaaagatc tatttcccca acgtatagtt tgaaaaatta ctctctttcg
      121 tttataatta agaatgattt tatgaaaggg agtgaaaaca catgaaattc tactcttatg
      181 actatgtact cagccaaatc ggtcagcaaa atggtatcat ggttggcttt gggattgttc
      241 tattagctgt gacagttttt ttgcttttaa ggtataccat gataaaaagg gaaccgaatt
      301 tcgtgagttg gtcatgattt cagctctggc cttatttagc tctgcttttg gtcagcatca
      361 cgacttatca aaacaatcaa gtttctaaca ataaatttca aacttcactt catttcatcg
      421 aggttgtttc caaagatttg ggagtagaca agtcagaagt ctatgttaat acttccacaa
      481 acacagatgg cgcacttatc aaggtgggag aacgctatta tcgtgcccta aacggaagtg
      541 agccagacaa gtacctgtta gagaaagtcg aattgtataa gacagacgca attgaactgg
      601 tggatgtgaa caaatgacac ttaattatat cgaaatttta atcaaactgg tcttgactct
      661 caaatagctc aacaacaatg ttcactttgt gaaacgtttg attgatggta agccaactct
      721 ccttatcaaa aatgggaata ttgacccata agcctgtcgt tcagttggtt tgtctgcatc
      781 ggatgtagcc ctcaaacttc gtagccaagg gattttccag atgaagcaag tcaaacgagc
      841 tgtgcaagag caaaatgggc aactcatcgt tgtgcaaatg ggagatgaaa atcctaagta
      901 tccagttgtg actgacggtg tgattcaagt agatgtcttg gaatcgattg gtcgtagcga
      961 agagtggttg cttgataacc tcagtaaaca agggcatgac aatgtagcca atatctttat
     1021 tgctgaatat gacaagggtg ctgttacagt cgtaacttat aaataagaaa aacctggggt
     1081 cttgtactct tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atgtaggtta
     1141 ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagcagcc tgcggctagt
     1201 ttcctagttt gctctttgat tttcattgag tattggcctc aggtttccat ttgcaatcag
     1261 aaagggattt tatgtccatt attcaaaaac tctggtggtt tttcaagtta gaaaaacgcc
     1321 gttatctagt cgggattgtg gccctggtct tggtttccgt cctcaatctc attcctccta
     1381 tggttatggg gcgagtcatt gatgccatca catcggggca attaactcag caggacctcc
     1441 ttcttagcct attttacttg ctacttgcag cctttggtat gtactatttg cgctatgtgt
     1501 ggcgtatgta tatccttggg acctcttatt gcttgggaca gatcatgcgg tctcgcttgt
     1561 ttaagcattt cacaaaaatg tcatcagcct tttatcaaac ctatcggacg ggtgatctga
     1621 tggcacacgc aaccaatgat atcaatgcct tgactcgttt agcaggtggc ggtgtcatgt
     1681 ctgcggtgga tgcctctatc acggctctgg tgactttgtt gaccatgctc tttagcatct
     1741 catggcagat gactcttgtt gccattctcc ccctaccttt catggcctat gcgactagtc
     1801 gcctagggag aaagactcat aaggcctttg gcgaatccca agctgctttt tctgaactca
     1861 ataacaaggt acaggagtcc gtatcaggta tcaaagtgac caagtctttc ggttatcagg
     1921 cagacgagtt gaagtctttt caggcagtca atgaattaac cttccaaaag aacctgcaaa
     1981 ccatgaaata tgatagtctc tttgacccta tggttctcgt gtttgttggt tcgtcctatg
     2041 ttttaacgct tttggttggc tccttgatgg ttcaggaagg gcagattaca gttgggaatc
     2101 tagtcacctt tatcagctat ttggatatgc tggtctggcc tcttatggcc atcggcttcc
     2161 tctttaatac tactcagcga gggaaggttt cttaccagcg gattgaaaat cttttgtctc
     2221 aggaatctcc tgtacaagac cctgagtttc ctctggatgg tattgaaaat gggcgtttgg
     2281 agtatgccat tgacagcttt gcttttgaaa atgaggaaac actgacggat attcacttta
     2341 gtttggcaaa agggcaaaca ctgggcttgg ttgggcagac aggctctggg aaaacgtcct
     2401 taatcaagct cctcttgcgt gaatacgatg tggataaggg tgccatttat ctaaacggtc
     2461 acgatattcg ggactatcgt ctgacagacc ttcgcagtct catgggctat gttcctcagg
     2521 accagtttct ttttgcgact tcaatcctag acaatatccg ctttggcaat cctaacttgc
     2581 ccctttcagc ggtcgaggaa gctactaagc tagcccgggt ttaccaagat attgtagaca
     2641 tgcctcaagg atttgatacg ctgattggtg aaaaaggagt cagtctttct ggtggtcaaa
     2701 agcaacggtt ggctatgagt cgggctatga ttttagaccc tgatatcttg attttggatg
     2761 attccttatc cgccgtagat gccaagacag agtatgcgat tatcgacaac ctcaaggaga
     2821 cgcgaaagga caagacaacc attatcactg cccatcgcct cagtgctgtt gtccatgcag
     2881 attttatttt agttctacaa aatggtcaaa ttatcgaacg aggcacgcac gaagacttgc
     2941 tagcgatgga tggctggtat gcccaaacct accagtctca gcagttggaa atgaaaggag
     3001 aagaagatgc agaataaaca agaacaatgg gctgtattga agcgcttgat gtcttatctc
     3061 aagccttatg gactcctgac ctttttggca ctcagttttc tcctagcgac gacggtcatt
     3121 aaaagtgtca tacccctcgt ggcttcccac tttatcgacc agtatctcag caatcttaac
     3181 caactagccg ttaccgtttt gctggtctac tatggtctct acatcctaca aactgtagtt
     3241 cagtatgtgg gcaatcttct ctttgcgcgc gtgtcttata gtattgttag ggatattcgt
     3301 cgagatgcct ttgctaatat ggagaaactg ggcatgtctt actttgacaa gacgccagca
     3361 ggttctatcg tttctcgttt gaccaacgat accgagacga ttagtgatat gttttctggg
     3421 attttatcca gctttatctc agcagttttt atctttctga caacccttta taccatgttg
     3481 gtgctggatt ttcgtttgac ggctttagtc ttgctctttc ttcctttgat tttccttttg
     3541 gtcaatctct atcgaaaaaa gtcagtgaaa atcatcgaga aaaccagaag tctcttgtca
     3601 gatatcaata gtaagctggc agagaatatc gagggaatca ggattattca ggcttttaat
     3661 caagagaagc gcctgcaggc agaatttgat gaaatcaacc aagagcactt ggcctatgcc
     3721 aaccgttctg tagccttgga tgccctcttt ttgagacctg ccatgagttt gttgaaactt
     3781 ctaggttatg ctgtcttgat gacctatttt ggctatcgtg gtctttctat cgggataacg
     3841 gccgggacca tgtatgcttt tatccagtac atcaaccgcc tctttgaccc tttgattgag
     3901 gtgacgcaaa acttttcaac actgcaaacg tctatggttt ctgcaggccg tgtctttgcc
     3961 ttaatcgatg agaggaccta tgagcctctt caagaaaatg ggcaagccaa agtcaaagaa
     4021 ggcaatatcc gttttgaaca tgtgtgtttc tcgtatgacg gtaaacatcc gattctggat
     4081 gacatttctt tctctgttaa taagggtgaa accattgcct ttgtaggtca tacaggttca
     4141 gggaaatcgt ctattatcaa tgtcctcatg cgcttttatg aattccagtc agggagagtt
     4201 ctcttggatg atgtggatat cagggatttc agtcaagaag agctgagaaa aaacatcggt
     4261 ttggttttac aggaaccctt cctctatcat ggaactatta agtccaatat cgccatgtac
     4321 caagaaatca gtgatgagca ggttcaggct gcggcagcct ttgtggatgc agattccttt
     4381 attcaagaac ttcctcaggg gtacgactcc cctgtttccg agcgtggttc gagcttctct
     4441 actgggcaac gccagctcct tgcctttgct agaacagtcg ccagccagcc taaaatcctg
     4501 attttggatg aagcgacagc caatattgac tctgaaacag aaagcttggt tcaagcttct
     4561 ctggcgaaga tgagacaggg ccgaacaact attgctatcg ctcaccgcct ttctactatt
     4621 caagacgcca actgcatcta tgtcttggat aagggacgca ttatcgagag tggaacccat
     4681 gaggaactct tgactctggg aggaacctat cacaagatgt atagtttgca ggcaggggcc
     4741 atggccgata ctctttgaaa atctctttaa accatgtcag ctttatctgc aatctcaaag
     4801 ctgtactttg attttcattg agtactagaa ggaaatcctt caaattacag atttctttca
     4861 ccgccttttc cattttgtgg tataatgaaa aatgttgaca aatagtataa taaaaacaaa
     4921 ggagaacagc atgctgaaat gggaagactt gcctgtggaa atgaaatcaa gcgaggttga
     4981 gtcttattac cagcttgtct ctaaaaggaa gggttcgctg attttcaagc gttgcttgga
     5041 ctgggttcta gcctttgtct tactggttct gacctctccc atctttctca tcttgagcat
     5101 ttggatcaag ttggatagca aggggccagt gatttacaag caagagcgtg tgacccagta
     5161 caaccgtcgg ttcaagattt ggaagttccg taccatggtg acggatgcgg ataaaaaagg
     5221 aagtctggtg acttctgcta acgatagccg tattaccaag gttggaaatt tcatccgacg
     5281 tgtccgtttg gacgaactgc ctcagttggt caatgtcctt aaaggtgaga tgtcctttgt
     5341 cggtacacga cctgaagtgc cacgttatac agagcagtat agccctgaaa tgatggcaac
     5401 cttgctcttg caagcaggaa ttacctctcc agccagcatc aactacaagg atgaggacac
     5461 catcatcagt caaatgacgg agaaaggtct gtcagttgat caggcctatg tggagcatgt
     5521 tcttcctgaa aagatgcgct ataacctcgc ctatctccga gagtttagtt tctttgggga
     5581 catcaaaatc atgtttcaaa ccgtgtttga ggtactaaaa taaagtagtc ataagaaaat
     5641 gagtacagat aaaaggagca aatcaatgcc aaattacaat attccatttt caccgcctga
     5701 tatcacagaa gcagaaattg ctgaagtagc ggataccctg cgttctggtt ggatcacaac
     5761 aggtcctaaa acaaaagaac tggagcgccg cttgtctctt tacacacaga cacctaagat
     5821 tgtttgtctc aactctgcga cagctgctct ggagttgatt ttacgcgttt tggaagtggg
     5881 acctggtgat gaagtcatcg ttccagccat gacctatacg gcttcatgta gtgtcattac
     5941 gcacgtggga gcaacccctg tcatggtgga tatccaagca gatacgtttg agatggacta
     6001 tgacctgctt gagcaagcta tcactgagaa aactaaggtg attatcccag tagagctcgc
     6061 agggattgtt tgcgattatg accgtttgtt ccaagtcgtg gagaaaaaac gtgacttctt
     6121 taccgcttca agcaagtggc aaaaggcctt taaccgtatt gtcattgtct ctgatagtgc
     6181 ccacgctttg ggatctactt ataaaggaca accttctggt tctatcgctg actttacttc
     6241 cttctcattc catgccgtta agaactttac aacggcagaa ggtggaagtg cgacttggaa
     6301 agccaatcca gtgattgatg acgaagagat gtacaaggaa ttccaaatcc tttcccttca
     6361 cgggcaaact aaggatgctc ttgccaagat gcaactgggg tcatgggaat acgatatcgt
     6421 tacaccagcc tataagtgca acatgaccga tatcatggct tcacttggtt tggtacaatt
     6481 ggaccgctat ccaagtttgt tacaacgccg taaggacatt gtggaccgct atgatagtgg
     6541 ttttgcaggt tctcgcatcc atcctttggc acacaagact gaaactgtcg aatcttcacg
     6601 ccacctctac atcacccgtg tagaaggagc aagcctagaa gaacgcaacc tcatcatcca
     6661 agaattggct aaagcaggaa ttgcaagtaa tgttcactac aaaccgcttc ctctcttgac
     6721 agcctataag aatcttggat ttgatatgac gaactatcct aaggcctatg ccttctttga
     6781 gaatgaaatt accctccctc ttcatactaa attaagcgat gaagaagtag actatatcat
     6841 tgagactttc aaaacagttt ctgaaaaagt gctaacttta tcaaaaaaat gacaaactac
     6901 agtcaagcga aagtgatcct gtccttaaaa agtctaattg agtgtaaaaa ctgttgtttt
     6961 caattgataa tagtttacac ctgtagttga ggctcctttc tcctcagaga gagaattttt
     7021 ataggatttt cctttcttgt gggagtcccg tggtttgaaa taagatgtga gcaatttggt
     7081 gtagcattta gaatccttac tagacatcat ttagaaaatc tagtgtcttg ttctagtttt
     7141 caattcaccc tattttttga aagacgtgag tttccatgag tgagattgtg gaaactcgcg
     7201 tctttttttt gttttcagaa tattgttcaa agttttgtgc ctgtctttca tgttctagtc
     7261 attcttttac atgatagaat ttatagcatg ttgatattat aataatacga atatcccata
     7321 tgtttagtga tgcttgctat acatcattag atctcctgcg agacaatcta taaaacactt
     7381 gtctacgatt acctatatgc cctattccag tattttagaa gcactgcatc tatttttatc
     7441 gaggttaaat ctagctttta tagaaggtct atttaagaaa tatattgtag tgttttagtt
     7501 tcaatccgcc atatgagcga tattaaggta aatatccctg gcgaatgctt gtatgacaag
     7561 gtatttgttc tttcatttat aatttacaac atatcaataa atttaaatat agtaaatggg
     7621 atattttata ttcaagctaa gaaagatagc atcacttttg aatggaaggc taaagagcaa
     7681 actaggaagt tggccataga tagctcaaaa ccctgctttg aggttgtaga tatagtaaaa
     7741 ggaaataaga ataggacaaa tcgatcggga cagtcaaatc gatttctaac aatgttttag
     7801 aagtagaggt gtactattat agtttcagtc tactatagaa ctgaccaagt cagtaaccta
     7861 gacttagggc aaggcggcac tgacctagtt tgaagagatt tccgaagagt ataaatttta
     7921 atattttctt gtgttattcc ttgacaattc aatttggaaa atatatgata aagataatga
     7981 cagcggtgtc attctatcta ttttaagaaa agtaataatc aattgttaaa aatagtaaaa
     8041 aaattggagg ttctgatgaa atattttgtt cctaatgagg tattcagtat tcgtaaatta
     8101 aaggtgggga cttgctcggt actattggca atttcaattt tgggaagcca aggtatttta
     8161 tcggatgaag ttgttactag ttcttcaccg atggctacaa aagagtcttc taatgcaatt
     8221 actaatgatt tagataattc accaactgtt aatcagaatc gttctgctga aatgattgcc
     8281 tctaattcaa ccactaatgg tttagataat tcgttaagtg ttaatagcat cagctctaat
     8341 ggtactattc gttccaattc acaattagac aacagaacag ttgaatctac agtaacatct
     8401 actaatgaaa ataagagtta taaggaagat gttataagtg acagaattat caaaaaagaa
     8461 tttgaagata ctgctttaag tgtaaaagat tatggtgcag taggtgatgg gattcatgat
     8521 gatcgacaag caattcaaga tgcaatagat gctgcagctc aagggctagg tggaggaaat
     8581 gtatattttc ctgaaggaac ttatttagta aaagaaattg tttttttaaa aagtcataca
     8641 cacttagaat tgaatgagaa agctacaatt ctaaatggta taaatattaa gaatcaccct
     8701 tccattgttt ttatgacagg tttatttacg gatgatggtg cgcaagtaga atggggccca
     8761 acagaagata ttagttattc tggtggtacg attgatatga acggtgcttt gaatgaagaa
     8821 ggaactaaag caaaaaatct accacttata aattcttcag gtgcatttgc tattgggaat
     8881 tcaaataacg taactataaa aaatgtaaca ttcaaggata gttatcaagg gcatgctatt
     8941 caaattgcag gttcgaaaaa tgtattagtt gataattctc gttttcttgg gcaagcctta
     9001 cccaaaacga tgaaggatgg gcaaatcata agtaaggaga gcattcagat tgaaccatta
     9061 actagaaaag gttttcctta tgccttgaat gatgatggga aaaaatctga aaatgtgact
     9121 attcaaaatt cctattttgg caaaagtgat aaatctgggg aattagtaac agcaattggc
     9181 acacactatc aaacattgtc gacacagaac ccctctaata ttaaaatttt aaataatcat
     9241 tttgataaca tgatgtatgc aggtgtacgt tttacaggat tcactgatgt attaatcaaa
     9301 ggaaatcgct ttgataagaa agttaaagga gagagtgtac attatcgaga aagcggagca
     9361 gctttagtaa atgcttatag ctataaaaac actaaagacc tattagattt aaataaacag
     9421 gtggttatcg ccgaaaatat atttaatatt gccgatccta aaacaaaagc gatacgagtt
     9481 gcaaaagata gtgcagaata tttaggaaaa gtatcagata ttactgtaac aaaaaatgta
     9541 attaataata attataagga aacagaacaa ccaaatattg aattattacg agttagtgat
     9601 aatttagtag tctcagagaa tagtatattc ggtggtaaag aaggaattgt tattgaggat
     9661 tcaaagggta aaataaccgt tttaaataac caattttata atttatccgg taagtatata
     9721 tcattcatca aatctaatgc aaatgggaaa gaacctgtta tacgtgatag cgatggtaat
     9781 ttcaatattg taacggagaa tgggctttac aaaattgtaa caaataattt aagtgataaa
     9841 aacgaaaaag aaaaaaacaa agaggaaaaa caatctaatt caaataatgt aattgatagt
     9901 aaccagaaga acggagagtt taactcaagt aaagataata gacaaatgaa tgacaagatc
     9961 gacaataaac aagataataa gacagaagaa gtaaactata aaatagttgg agatggcaga
    10021 gaagctgaaa atcatattaa taaatctaaa gaaatagtag atgtaaaaca aaaattacca
    10081 aagactggtt cgaacaagat tatggaacta ttcttaacag tgacaggaat tggtttactt
    10141 ttgacactaa aagggttgaa gtattatggt aaagataaat aaaatttgtt cgattacaag
    10201 gaagttccgt agaaaatgag gatattgtag gttcacaaaa tcagtatttt tggattattg
    10261 gtggagctac agatttatat aattctaaag aggagatagg ttattcagtc tcagaagttg
    10321 tacatatttt atcagaaagt ttgtcggtta attgtaaaga atcaaaaact cttaaacaaa
    10381 tatttgaaac tgctttactc gaggttaaag atgaaatcgg tttaaactca tatgaattaa
    10441 cagagtatag taaaatgaaa taataatagg acaaatcaat caggacagtc aaatctattt
    10501 ttaacaatgt tttagaagta ggggtgtact attctagttt caatctacta tattatcgct
    10561 taccaacatt tgcttttata tttgctaaac tttcagaaaa aagttggagt atatgatgct
    10621 aggtgattgc gtcatgttag taaacgaaat ggaaataact gatcatagag tagataactt
    10681 atttgaaaaa gggaaaaatg agataaaaga tccatgtagt agatttagca ataggacata
    10741 taaaagcttt agaaaaagta tctgaaaaaa cagatgttta tatctataac ctatgctcgg
    10801 gagaaggcac tagtgtatta caacttgtaa atacatttga aagtgttaat aagatctcta
    10861 ttccttataa aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag
    10921 acaaagcata taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag
    10981 atacatggaa ttggcaatca aaaaatccca atgactataa ttgatgatac tgtctatatg
    11041 agtgctgtat tttggaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat
    11101 aaattaaaaa aaatgtttga cagcgcttga caaaggaaac ggtttcattg tataatgtaa
    11161 acatagtgac accgatatca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa
    11221 aattaagttc aaagagaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa
    11281 tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga
    11341 attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat
    11401 tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga
    11461 tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt
    11521 ggatgaagaa attcatatgc gtgtaactga aatgggaaaa caaaacatac tagttgaacc
    11581 tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc
    11641 aggtgttcgt ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg
    11701 gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga
    11761 aattttatta gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga
    11821 agatatgaga caatttgttt catatcacga aaaatttaaa taaaataata aaaaaggaga
    11881 acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac
    11941 tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa
    12001 agctgataaa agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga
    12061 ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg
    12121 cgctcaatta gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt
    12181 tggaattggt gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa
    12241 gcctaaatgg ttagataaaa ttgatcaatc tttatcagat aaagataatt attataaccc
    12301 agttattgtt caacccttgg tattgattgg agctcctgat gcaaaagaaa tgccaaaaga
    12361 ctggacagag ttagctagta aatataaggg acaatattcc atttatggct taactggtgg
    12421 gactggacgc gccatttacg caagtattct agttcgttat cttgatgaaa aaggtgattt
    12481 aggagtatcg gaaaagggct gggaagttgc aaaagaatac tttgcaaatg cctatactct
    12541 tcaaaaaggt gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg
    12601 tatgatctgg ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt
    12661 tatgactcct gagattggtg taccatttgt aactgaacaa actatggttt taagcactag
    12721 taaaaaacaa gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt
    12781 agaatatagt aaaaaatttg gctctatccc tgccaataaa gatgccctaa aagagttacc
    12841 tgaagatacg aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt
    12901 tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat
    12961 aagagttatt ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag
    13021 agaggctttt ggtttagtaa tagagggagt tagtgagatg attaaatttg ataatattca
    13081 aattaaatat ggtgattttg ttgcaattga taatctgaat ttagatatac atgaagggga
    13141 attctttaca tttcttgggc cttcaggatg tggtaaatca actactttga gagcattggt
    13201 aggtttttta gatccatcat caggaagtat tgaagttaat ggaacagatg tcactcattt
    13261 ggaacctgaa aagcgtggaa ttggtattgt atttcaatct tatgcgctat ttccaactat
    13321 gactgttttt gataatattg catttggttt aaaagttaag aaggtagctc cagatgttat
    13381 taaagctaaa gtatcagcag tggcagcaaa aattaagatc tctgatcaac agttacagcg
    13441 taatgtatca gaattatctg ggggtcaaca acaaagggta gcattggctc gtgctctggt
    13501 tcttgaacct aaaattcttt gtctagatga accattgtca aaccttgacg caaaattacg
    13561 tgtagatttg agaaaagagt tgaaaagact tcaaaaagag ttaggtatta ctactttata
    13621 tgttactcat gatcaagagg aagccttgac tttatctgat agaattgcag tctttaacaa
    13681 tggatacatc gaacaggtcg gtacaccagt agagatttat cataattctc aaactgaatt
    13741 tgtatgtgat tttattggag atattaatgt tttgaccgat gaaacagtcc acgaagtatt
    13801 attgaaaaat acaagcgttt tcttagagga taaaaaagga tacattcgat tagagaaagt
    13861 tcgattcaat cgtgaaactg aacaagattt tattctaaaa gggacaatta ttgatgttga
    13921 gttttctgga gttacaattc actatacaat aaaagtttct gaaagtcaga ttcttaatgt
    13981 aacaagtatt gatagtcagg ctgctattag atctgtcgga gaaagtgtgg aattatttat
    14041 cacaccatca gacgttctgc aattttaagg aggtgcagta tgcgtcataa attaaattta
    14101 aaagattggc ttattcgttt agggttaatc tggttcttag taacatttat tatttatcca
    14161 aactttgatc tagtagtgaa tgtatttgta aaaggaggag aattttccct tgatgctgta
    14221 catcgtgttc taaaatctca gagggcactt cagagtatta tgaacagttt taagttagca
    14281 ttttcactca ttattacagt taatgtcgta ggtattcttt gtgttctatt tacagagtac
    14341 tttgatatta aaggtgctaa aattttaaaa ttaggttata tgacctcttt aatttatgga
    14401 ggagtggttt tagcgactgg atataaattt gtctatggtc cttatggatt gattacaaaa
    14461 tttttacaaa atgttatccc ttctttagac tctaactggt ttattgggta tggtgcagtc
    14521 ttattcatta tgacattttc aggaactgct aatcatacat tgtttttaac aaatacaatt
    14581 cgaagcgttg actatcacac tattgaggct gctcgaaata tgggagcaaa accatttact
    14641 gttttccgaa aagtagtgtt accaacctta attccaactc tatttgcact tactattatg
    14701 gtttttctta gtggtttatc tgcagtagca gcacccatga ttgttggtgg taaagaattt
    14761 caaactataa atccaatgat tattacattt gcagggatgg ggaattctcg tgatttagct
    14821 gccttacttg caattatttt aggtattgca actacaattt tgcttactat catgaataag
    14881 atagaaaaag gtggaaatta tatttctatc tctaagacta aagcgcctct taaaaaacaa
    14941 aaaattgcgt ctaagccttg gaatatcatt gctcacattg tagcatatgg attgttcaca
    15001 gttttcatgc ttccactaat ttttatagta ttatactcat ttacagatcc agttgcaatt
    15061 caaacaggta acttaacatt atcaaacttt actttagaaa attatcgctt attctttagt
    15121 aatagtgcgg cattctctcc attcttggtc agctttattt attctattat tgctgcgaca
    15181 acagcaacaa ttctcgcagt tgtatttgct cgtgttgtca gaaaacataa atctcgtttt
    15241 gatttcttat ttgaatatgg tgctctactt ccttggttac taccaagtac acttttagca
    15301 gtaagtttat tatttacttt taatcagcca caatttcttg tcttgaatca gattttggta
    15361 ggtagtttgg taattctact tattgcatat atagttgtaa aaatcccatt ttcttataga
    15421 atggtacgtg ctattttatt tagtgttgat gatgagatgg aagatgcagc aagaagtatg
    15481 ggtgcttcac ctttttatac tatgatgaag gttatcattc catttatttt accggttgtt
    15541 ctctctgtta ttgctttaaa ctttaactct ttattaactg acttcgactt atctgtattc
    15601 ctttaccatc ccctagctca accattaggt attacgattc gatctgcagg tgatgaaaca
    15661 gcaacatcta atgcacaagc tctggtattt gtttatacaa ttgttctgat gattatttct
    15721 ggaacggtat tatacttcac acaaagaccg gggcgtaaag taaggaaata atcatgacag
    15781 ccactagtct tgggttatca aatattgaaa tagttgtcag gattgtttta tcagtagtca
    15841 ttggtagtat aattggttta gagagaggga gcaaatccca gcctgcaggc atccgaactt
    15901 atagtattgt ttgtctagct gcatgtttga ttatgatgac gaatgaatac gtatcttata
    15961 aatttgggac aggagatcct acacgattag gagctcaagt tatatcaggt gtgggttttc
    16021 taggcgctgg aacgattctt attacagata aaaagaaaat tacaggtctg acaactgcag
    16081 caggcatttg ggcttcggca ggaattggat tagctattgg agtaggtttt tatgagggag
    16141 ctcttttagt agccatttct gtttggggtg tgatatccat gttccaacca ctaaaaaaat
    16201 atctgcaaaa tcgttctaaa atgattgaat tgtatatagt ggttaaatct acagaagcct
    16261 ataatcgtgt attggtttat tgtgcagaaa atggtatcag aatgaccgat tcaagaacag
    16321 cgtttggaga tgttaattct gacagaattg aatactttga tgttccggac aaaaaaatag
    16381 cgtcatttat tactctggaa ttatcaggta gatttgaaca tcttcgactg atggaagaaa
    16441 ttgctaatat tgtaggtgtt atttatgtcg aagaaattag ctgaaattta gtaaacaaag
    16501 ggacagatgt ttttgtcctt ttgcttttta gatgttttaa tcatctaatt tttgagtaga
    16561 tttttgctca gaggttttta tgaaagatta taaaatcaat tttgatttag gtaaaataga
    16621 atattttgat aataattgtt tgatacaagt atacaaattt atttcttttt atgatatttg
    16681 tgaaatggtg tttgcctttc atttacctcc tgatgagttg ataacaaatg ttatctttaa
    16741 agaaaaaatt aactctatgt taaaatgtta cattgacagg ctattatatg tttttataaa
    16801 tcctacacat tttactgaaa aagttaatct acaattttat ggcagttttt tctcatatga
    16861 atttatttgt cgtgaagttg gaaacattct taaaaataaa ggtgtgaaat gcaatttaaa
    16921 cttttttgaa ggggaagaat atttgtaaaa ttaattttgt gaatttgtgg atcttaaata
    16981 atttactaaa ttctcttgtt aaaaaaaatt aaatattgta tagtaatatt agaatgtttg
    17041 taatagagga ctgaaatgaa aaatataaat gggaaaaagg taactattta tgatattgca
    17101 cgtttatcag gtttttctcc aaaaacagtt tcacgagtta ttaatggtgg agtaaatgtt
    17161 aaagaagaaa cttatcaagc gattcaaaaa gttatagagg aattgtcgta tattccaaat
    17221 gcgtatgcaa aaaatttaac taaaaaagaa gctataaata tattgatttc tgtaaaaaaa
    17281 atcgactctt ttcctttaat ttggtttcat acgctgttag ataaagtgtt acggacgtgt
    17341 aaagaatttg gtgttaatgc tatagttgag tactttggag aggaggatac aattagtaat
    17401 tcgattatat caagcacagg tagcctagta gatggtgtta ttgtttttta tgaaagtgta
    17461 gatgatatca gaattcagta tttaaagaag aaccatatgc cttttcttgt tttcggtgaa
    17521 tctcaaacgt ctggagtagt ctatgtatct aataataatt ttcaagctac ttatgatatg
    17581 atgaaagctg taactgaaga aaaatttaaa aatatgtggt tgcttatggg aggagaatcc
    17641 catgttaata aggatcgtga aagaggtgtg cgttcttttc tgaatgataa aaattacttt
    17701 atggatttaa aagtcattta tggcttatct acaattgatt cagtttattc ttatgcaatg
    17761 cagcacttga ctacccaaaa ttatccggac attatttttg tttcaggaga tgaaaaggtt
    17821 cagggcttga ttcgtgcgtg ctatgagaaa ggaattctta ttccagatga tatttctatt
    17881 attggatttg ataatattcc tatttctcag tattatactc cagctttgtc tacaattgct
    17941 cccaattatg ttaaattggc taaagaaatg atagaaggtg ttttagcaat tattaaaggg
    18001 gaaagtgtca catctgttga agtttctcct aaatttgtta ggagacagag tttctagtat
    18061 tgtttaattc ttgaaaatcc tagtggaaaa gatggagtgt tctaaaataa gttctgttta
    18121 gcctccattc agtttctatt gagttggatc caatttctaa caagtgggac atgttcatgt
    18181 tcgatctaag gaagacatgg tcacattcga atgatatttt caaaaaaatc gtaaaaaagt
    18241 cttgacaaag aaaaaacaaa gtattaaaat aagttcaaca aatcagaaaa gtaactattt
    18301 ttgatcttca gggagcctgt ggtggttgtg aataggtggt tggaagtagt gaaagtgggc
    18361 tgattttgaa aatgaatttg aaacaatgaa aattcggtgc gcacacctta cagtgcagct
    18421 tgttgttaaa caaggcagag atgtaaaggg atagtccctt tataattgag gtggcaccgc
    18481 gttaccaacg ccctcacacg gaagtatatt ttgtgtgtgg gcttttttct atccgtcgtt
    18541 tggtttatct tttattaggg ccttaagtcg ctttgatgaa cttgagttct atctacagct
    18601 ccttgcctac tactaaaagc aaacaaaaag ctggactaat acgaaaaaag ctagtaatac
    18661 tcaatgaaaa tcaaagagta aactaggaaa ctagccgcag gttgctcaaa acactgtttt
    18721 gaggttgtgg atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga
    18781 actgacgaag tcagtaacca tacctacgat aaggcgacgt tgactcggtt tgaagagttt
    18841 ttcgaagagt ataaaggtgt accgagatga atatctcttc atcaatgtct ctggtcgtgg
    18901 aggcaaggac ctagctgcga ttgcagatta ctagaagcta aaaaataata gatggaaaaa
    18961 ttacagttct ttctctcaca gagagcttgt ggttgctgaa aacaagcaga gaaagctgta
    19021 aagttgggtt catctgaaac gagagaagaa aacatcattc tcaagggagt gccctttatc
    19081 gcacagcctg ttacaggagg tatctgagat aggaatgaga gataggagaa atcctataat
    19141 tgaggtggca ccgcgaattt cgtcctcacg caagttattt tgcgtgggga tttttcatac
    19201 agtcgccacg aactagaatt agaactgaaa gggaaattac aatggaacga atcattcatg
    19261 gagatgtctt atcaccaatc ttggcttata tgcgcttaaa ggggcaacat aaggttattt
    19321 tagagagtat tccgagagac aaggaaacag ctcgtttttc tatcctagcc tataatccag
    19381 tttttgagat taagtttgaa aatggagttc tctatcaaaa tggtcaagtg attgatcggg
    19441 atcccttgga tctcctttat gaagtgattc ataagagtca gcaccactca gagctacctt
    19501 ttggtggtgg agccattggt tttgtgggtt acgatatgat ttcgctttat gaagaaattg
    19561 gtcaaatccc tgaggataca attgggacgc cagacatgca tttctttgtc tatgagagct
    19621 atatggtctt tgaccacaag aaggagaaga tacatgtcat agaggatgct ctctatagtg
    19681 agcgcagtca agaggtcttg gaaaaatcct tgaaccaagt gcttgaggaa ttacgcattc
    19741 ctgctccaaa tgaatttgaa gacttggatt tatcaccact tgacttcaaa ccgcatatcg
    19801 ctccacataa gtttgaggga atggtagaaa cagctcgtga cttgattcgt aatggtgata
    19861 tgttccaatg tgtactcagc cagcgtttct cagcagaagt tactggaaat ccatttgact
    19921 tctacagaaa tctccgcgtg atcaatccat ccaattacct ctatttctat gattttgggg
    19981 attatcaaat catcggagcc agtccagaaa gtttggtttc tgtcaaaaat ggcatcgtga
    20041 caaccaatcc gattgcaggg acgcgaccaa gaggggctac ggatgaagaa gacaaggcct
    20101 tggcgactga cctcctctct gatgagaagg aaacagcaga gcatcgaatg ttagtagacc
    20161 tgggtcgtaa cgatattggc cgcatctctg aaacggccag tgtccaagtc actaagtata
    20221 tggaagtgga gctcttccgt tatgttatgc atctgaccag cgtggtcaag gggcgtttgc
    20281 ttccagaact cattgctatg gatgccttga aatcaacgct tccagctgga accgtttctg
    20341 gagcaccaaa aattcgagct atgagacgca tctatgaact ggaaacggaa aaacggggcg
    20401 tatatgcagg agcaatcggc tacttgtctg cgacgggtga tatggatttg gccattgcca
    20461 ttcgaaccat gattctcaaa aatcaaagag cctatgtgca ggctggggca gggattgtct
    20521 acgactctat cgcccaaaac gaataccaag aaaccattaa caaagcaaaa tctatgacta
    20581 gaattggaga actaagacca tgattttatt gattgacaac tatgattctt ttacctataa
    20641 cttggcccaa tacatcggga attttgcaga agttcaggtt ttgagaaatg atgattccaa
    20701 gctgtatgaa gaagctgaaa aagcagatgg tctggtcttt tctcctggtc ctggttggcc
    20761 agttgatgct ggaaagatgg aagacatgat tcgtgatttt gcaggcaaga agccgattct
    20821 agggatttgt ttgggccacc aagccattgc agaagtcttt ggtggtaagc taggtttggc
    20881 tccaaaagtc atgcatggga aacagagcaa tatcaacttt gaagcgccat ctgttttgta
    20941 tcaaggtatt gaggatggac gtgcggtcat gcgttatcac agtattttga ttgaggaaat
    21001 gccagaagac tttgaagtga cagctcgttc gactgatgac caagccatca tggggattca
    21061 acataaaaac ctaccgattt atggcttcca gtaccatcca gagagcattg gaacgccaga
    21121 cggcttgtct tctattcgga attttatcga ggaggttgta aagtgaggaa actaggatga
    21181 aagagattat tgaaaaacta gcaaaatttg aaaatttatc aggtgtggaa atgacggatg
    21241 tcattgagcg tatcgtaact gggcgtgtaa ctgaagcgca gattgcttct ctcctcttag
    21301 ctcttaagat gaagggggaa acacctgaag aacgcacagc cattgcccaa gtcatgagag
    21361 gacatgccca gcatattcca actgagattc atgatgccat ggacaactgt ggtacaggtg
    21421 gggacaagtc tttcagtttt aatatttcca caactgcagc ctttgtcttg gctggtggcg
    21481 gtattcacat ggccaagcat ggtaaccgct cgatttcttc taaatctggt tccgcagatg
    21541 tcctcgaagc cttgggaatc aatcttgacc tcaaaccagc tgaactaggt aaggtctttg
    21601 ataaaactgg aatcgtcttt ctcttcgcta aaaatatgca cccagctatg aaatacatca
    21661 tgccagctcg tttggaattg ggaattccaa cgattatgaa cttgactggt ccactgattc
    21721 atccaatggc tttagaaaca cagcttcttg gaattagtcg tccagagctc ctagaaagta
    21781 cagctcaggt tttgaaaaat atgggtcgca aacgtgccat cgtggttgct ggaccagaag
    21841 ggttggatga agctggcttg aacggaacaa ccaagattgc acttcttgaa aatggcgaaa
    21901 tcagcttgtc aagctttact ccagaggatt tgggaatgga aggctatgct atggaagata
    21961 ttcgtggtgg gaatgctcag gaaaatgcag aaattttgct tagcgttctg aaaaacgaag
    22021 caagtccatt cttggaaacg acagtcttga atgctggtct tggtttctat gctaatggta
    22081 agatcgatag catcaaggaa ggagttgcct tggcccgtca agtgattgct agaggcaagg
    22141 cccttgaaaa actcagactg ttacaggagt accaaaaatg agtcaggaat ttttagcacg
    22201 aatcttagag cagaaggcgc gtgaggtgga gcagatgaag ctggagcaaa tccagcctct
    22261 gcgccagacc tatcgcttgg cagaattttt gaagaatcat caggaccgct tgcaggtaat
    22321 cgctgaggtc aagaaagcta gccctagttt gggagatatc aatctcgatg tggatattgt
    22381 gcaacaggcc cagacttatg aagaaaacgg agcagtgatg atttcggtgt tgacagatga
    22441 ggttttcttt aaagggcatt tggattatct acgggaaatt tccagtcagg tagagattcc
    22501 gacgctcaac aaagacttta tcatagatga aaagcaaatc atccgcgctc gcaatgcagg
    22561 tgcgacagtc atcttgctca ttgtggcagc cttggcagaa gaacgtctta aggaacttta
    22621 cgactacgcg acagtgcttg gtctggaagt cttggtggaa actcacaatc tagctgaact
    22681 agaagtggct cacagacttg gtgcccagat tatcggggtc aataaccgca acttgaccac
    22741 ctttgaggtc gacttgcaga ccagtgtaga cttggctaaa catttcaaag atgattgctt
    22801 gtacatttct gaatctgcta ttttcacagg gcaggatgcg gaacgactag ccccatactt
    22861 taacggaatt ttggtaggga cagctcttat gcaggcagaa aatgtggccc agagaatcaa
    22921 ggagttgcag attgacaaag gttaagattt gtggactatc gaccaaagaa gcggtggaaa
    22981 cagccgtttc agcaggagcc gactatatcg gttttgtctt tgcacctagt aaaagacagg
    23041 tgactttaga agaggcagct gagctggcaa agcttattcc ttcaggtgtg aaaaaggttg
    23101 gagtatttgt ttcaccaagt cgggtagaac tgctagaagt cattgacaaa gttggcttgg
    23161 acttggttca agttcacggt caggtggcag atgatttatt tgagaatttg ccttgtgcca
    23221 gtattcaggc tgtgcaggta gatggaaatg ggcatgtccc caattctcag gcagattatc
    23281 tactctttga tgcccctgtg gcaggaagtg gtcagtcctt tgattggggt caactggata
    23341 cgactggact agcacagccc ttctttatcg caggtggcct taatgaagat aatgtagtaa
    23401 aagcaattca acattttact ccctatgcag tagatgtatc gagcggagtg gagacagatg
    23461 gacaaaaaga tcatgaaaag attagaagat ttatagagag ggtaaagcat ggcatatcag
    23521 gaaccaaata aagatggatt ttacggaaaa ttcggcggac gttttgtccc agaaacattg
    23581 atgacagcag ttttggagtt ggagaaggcc taccgtgaaa gtcaggcaga cccaagtttc
    23641 caagaggaat taaaccaact tttgcgccag tatgtgggac gtgaaactcc cctttactac
    23701 gcaaaaaact tgacccagca tatcggcgga gccaagattt atctcaaacg ggaagacctt
    23761 aaccatacag gagcccacaa gattaacaat gccttaggac aagtttggct tgccaaacgc
    23821 atgggtaaaa agaaaattat cgcagaaact ggtgctggtc agcacggtgt ggcaactgca
    23881 actgctgcgg ccctctttaa catggaatgt accatctaca tgggtgagga agatgtcaaa
    23941 cgccaagccc tcaatgtctt ccgtatggag cttttgggag ctaaggtcga ggccgtgaca
    24001 gatggttcgc gcgtgctcaa ggatgcggtc aatgcagctc ttcgttcatg ggtggctaat
    24061 atagatgata cccactatat ccttggttct gccttggggc ctcatccatt tccagaaatt
    24121 gttcgtgact tccaaagtgt cattggtcga gaggctaaac aacagtaccg tgacttgaca
    24181 ggacaaaatc tgccagatgc cctagtagcc tgtgttggtg gtgggtcgaa tgccatcggt
    24241 ctcttccatc cctttgtaga agatgagtca gtagccatgt atggagctga agcggctgga
    24301 cttggtgtgg atacggagca ccacgcagct accttgacca agggtcgtcc aggtgtcctt
    24361 cacggttccc tcatggatgt gctccaagat gcccatggtc aaattcttga agccttctct
    24421 atctcagcag gtttggacta tcctggtatc ggtccagagc attctcacta ccacgatatt
    24481 aaacgtgcca gctatgtccc tgtgacagac gaagaagcct tggaaggatt ccaactcttg
    24541 tctcgtgtgg aagggattat cccagccttg gaatctagcc atgctatcgc ctttgcggtg
    24601 aaattggcca aagaacttgg accagaaaag tctatgattg tctgcctatc aggtcgtggg
    24661 gacaaggatg tggttcaagt caaagaccgc ttggaagcag atgcagcaaa gaagggagaa
    24721 gctcatgcct aagacactaa cagaaaaatt gaatgctata aaagcaactg gaaaaggaat
    24781 ttttgttccc tatatcatgg ctggtgacca cgagaaaggt ttggacggtc ttgctgaaac
    24841 aattcacttt ttagaagatt tgggtgtctc tgctattgaa gtgggtattc ccttttcaga
    24901 ccctgttgca gatggacctg ttatcgaaga agctggcttg cgcagtttag cccacgggac
    24961 ctctacccag gctttagttg aaaccttgaa aaccattgaa acagagattc cactggtcat
    25021 catgacctac ttcaaccccc tctttcagta cggtgtggag aactttgtca aagatctggc
    25081 tgatacagct gtgaagggct tgattatccc agacttgcct catgaacatg ccaactttgt
    25141 aaaaccattt ttggcagata cagatatcgc cttgattcct ttagtaagct tgaccacagg
    25201 aattgagcgc cagaaagagt tgattgaagg cgcggaggga ttcgtctatg ccgttgccat
    25261 caatggggtg acagggaaat caggcaatta ccgtgcagat ttggacaagc acttggcgca
    25321 acttcatcaa gtggccgaca tcccagtctt gacaggtttt ggtgtatcta gtcaagccga
    25381 tctggaacgc ttcaatgcgg tgtcagatgg tgttatcgtc ggttcgaaaa tagtaaaagc
    25441 tctccaccaa ggagagccga ttcaggattt tatcagacaa gcagtagctt accaaaaata
    25501 atcaaacaag tagcaagtaa gaggaaaggc acgaaaggaa gtctttcctt tttcttttgc
    25561 aggagaaagg ctagttttat agtgaattga atctggaata ttacactacg gttcctaaaa
    25621 tattttaaga aagtgatttg aatttcccaa taaatttgtt cagtttttaa ttgattttac
    25681 tatagaagat ataattttct aaattactct gacacagaac tttaagaaaa agctaattat
    25741 tgtagtaatt tctttaagaa aatgatataa ttcattaaaa agtatttgga ggaggaagaa
    25801 ttatgttgaa tcaggatctc tttgattcgc ttgaggcaca aaaaattgta gatactttga
    25861 tgaaagggca aaaagattat gtagatgaac gtctagaaaa aagattatgt agatgaacgt
    25921 ctagaaaaaa gagagacaat gatagtgtcg aatggttatg catggacgcg acctaatcat
    25981 attgatactg catttgcatc agcagatttg tttgagtata aattacaatt agcaggacag
    26041 acttggggat atttagaatt tgaaacaaat acagaaaaat atgggaaagt attgttaatt
    26101 ataaagggta agaagcgact tacgaaccaa tttcctttgg tacaaaaaaa taagagtggc
    26161 tacttatttg aatatgctca aatgaataca ctttatctta atcaacattc ttcctacaaa
    26221 aatgatgaag atagtcattc ctttccaatt cagatggagt tagtttctga tgaaatgatt
    26281 caagaaattg aacaagctac caaaaattcg aatatcgaaa aatttatgat tttaacttat
    26341 gaggcggact cagaaaacaa tattatatat gtagatgttg ttatgcctga tgcacgaact
    26401 ggtcagttac acttgattca agatttgtct gagtatattc aatcaagttc gtaccatttc
    26461 gaagaagcta aatatcaaga tattcctaat ttttcagaat tatcggaaac agaagatttt
    26521 gaaattattc caagaataga aaaacaagaa ggtcaaaagt agtaaggagt gtgtaaatgt
    26581 ttaatggtcg ggtattgaaa gaattacggc tgttaaatgg tttaagtaga gcagaattgg
    26641 ctcagagaat taatttaacg gaacaagcca tttggcagtt tgagtccaac gaaacgaaac
    26701 ctaaattatc aaccaaaatg catttggcca accaatttca tgttgattta acttattttg
    26761 aacaggaaga agagagcatt cgatttgatt cttctgtaat tgcctttaga aatgcagacc
    26821 tagcaacacg gaaaacaata gatattcaaa ctatgtattt acataaggta gatagtttga
    26881 ttgattattt tgaaagtttt gtaattatac ctaatattac aattcatgat ctaagtaatg
    26941 tagtgagtga atcttatcat aagggagaat ccattgagga attggctctt tatgccagag
    27001 aaaaattagg tatttcaaaa gataatcatg atttgcttta taaattagaa cgttcaggca
    27061 tctatatcgt ggaacgatta attaatggcc aagctgatgc ttatagcgca tggtcaaaat
    27121 tgggaagacc ttatattgtg ttgggaacga ataaatcatc tgtacgtcga aattttgact
    27181 tagctcatga gctaggacat attcttttac ataaatataa agatatgaat gaagatggcg
    27241 atcgtttgga gcaagaagca aattattttg catcatgttt tttattgcca aaagaagagt
    27301 ttttagtcaa atttgaagag agggttggca agcgtgtcag caatcctgat agttatattt
    27361 tattgaagtc ggatttgaat gtttcgatac aggctttaga gtatcgagct tttaagttag
    27421 gattattgac tccaaagcaa cattcttact tttatcgtca aattgcgcaa aaaggttaca
    27481 aaatgattga acctttggat gatcaaattt ttgttaaaaa accaagcaaa gtaaagagta
    27541 ttctggacgt cgttttgagt aatcatctag tcagtctagc gactataatg tctaaacaaa
    27601 gtattcgttt acagtttata agcgaaatat tttcagtcga aatgaaattt tttgatcagt
    27661 atcaagaaga tagaagaaca gatcgatttg ataacatcat ccctttgtac aaaagaaata
    27721 atttataatt taactgtgaa ataatttcat gaaggacata tggcagaaat tggactttat
    27781 caaacaagca gtagcttacc aaaaataatc aaacaagtag caagtaagag gaaaggcacg
    27841 aaaggaagtc tttccttttt cttttgcagg ataaaggaaa ggatacccat cgcagaagca
    27901 aactgaatca agattagtaa ctccgttacg ctaaagacga gagcacaaga agctaaaaag
    27961 aggaaatccc ctgcgcccat gcggatatcg ataaaatgag ccaaaattcc aagagcaagg
    28021 aaggagacca tgaccagatt ccagccagag taagctatga ggattaggtg gaaagtcatc
    28081 cagaccagta agggatattc ctgatggcga aagtcgtaga tacccaaggt caaaccagca
    28141 gtgattagga tgacttgtcc caaggagagc catccccaag agtaaagcag aaagatgagt
    28201 cctaagccta gttcaaagag ggcataccag acgggatagc ggaccttgca gtagcgacag
    28261 cgaaaatgat taaaaacctg cgatagaatc ggaatcaaat ctaagggacg caagcgagtc
    28321 tgacaggaat cgcagtgact ggctgaactg ataatggatt gctctggaaa acggtcaatg
    28381 accaaaccaa gaaaggaggc gagaatgctc ccgacgagaa aaaaataaaa atcaatcata
    28441 cttatctatt cgtaaaaaat gggagaaata gtataatgga gaaacataga taagatggtg
    28501 aggaaaagat gacaattcgt tttgaagaaa aggtgagcac agaaaacgct caattcgtat
    28561 gccagtggtc caactcccta ggcaaatcct ttcaagaaca atggatggga ccaaggattc
    28621 cttttctact gacccttcaa gccttgcaag acttggaagg agtcttttca atctttgatg
    28681 aacaagagtt tgtggaactt atccataaaa tcaggctaga agacagcaat cttcatatcg
    28741 ggagattttt tatcaacccc cagaaacagg ggcaaggctt aggtagtcag gctttaagga
    28801 aatttgttag tttggccttt gaaaatgaag atatagatag tatttctcta aatgtcttag
    28861 aggcaaatca aagagctcag aatctttacc aaaaagaagg atttgaaatc gttcaaatgg
    28921 ttgaagcacc tgtacgaaaa tatatcatga aaaaggggag atagaaagca aacagccttg
    28981 aaatcaatgt tgactgcgat tatgaacctg aatcagcccc tcaaaaggga ctgtatatga
    29041 atgaacgtta ccagtgttta aaaactaaag aatatcaggc acttttatct tccaagggta
    29101 gacaaatttt cgctaaacgt aagattgata tgaaatctgt ctttgggcag ataaaggttt
    29161 gtttgggtta taagagatgt catctgagag ggaagcgtca agtgagaatt gacatgggat
    29221 tcgtactcat ggccaacaac ctgctgaaat ataataagag aaagaggcaa aattaaaaag
    29281 ctagagttcc gcaattggga atctctagct ttttgttttc tgagaatcat cttgactcag
    29341 actcttttga ctaatgttac taaaaagata aagtaacttt taaccttatt tatcgtcgcc
    29401 actcaacatg tttttaacac cttctacagc accttctaca gcgtctttgg catcttcggc
    29461 gacttctttt actttagaaa caactttttc agctactcct tctttttcca ttttttcatc
    29521 accgatggct ttcccaacac cttctttaat agaaccttta gcttgattta atttttcttc
    29581 tactgacatg ataatttctc ctgttatatt tattttatct tagtttacac gagtgttttc
    29641 gtgagatact acaccatttg ctgcaccttt aacagcttct acaccttcgc taactttttc
    29701 ttgaacagtt gagaaaccag atccaagacc agatttagct ttttcgaatt gttctgaagt
    29761 gaattctcct gttgattcag caacgtcaga tacgcgatct tgaaggctta ctgaatctgc
    29821 ttcatgctgt tctttagttt tgatgtcgac aacgtttacg ttgatttcaa caacttccaa
    29881 gtcagtcatt ttagcaactt ctgaagatac gatttctctg atttctgaat ataaagctgg
    29941 aacatttttt tggtactcaa caataacgtt taagtcaact gcaacttgtg ttttaccaac
    30001 ttctacgtta acaccacttg ttacgtcatc gctgttaacg attttttctt taagatttga
    30061 gaagaaacca ccatcgattc ccaaaagacc tgaaacgttt tctagtgaaa gaccaatgat
    30121 tttttggata actttatctt cgtaagtaag ttcccctttg atttcgtgag ctacaacagt
    30181 agcatctttc ttttctacgt tagtgtttgt gtttttttcg tttgacatat gaaactcctt
    30241 taattaaatt agtaattttt atttatctat atagtttttt tcgatatata atccagctgc
    30301 aactcccagt gctcctaaaa tcaatacaaa tattgttttg aagaagccaa aggagacaat
    30361 caaacaagca agaaatacgc ctatgagacc agcgataatt ggatatcgat attgtttaag
    30421 ccattccatt ttttacttcc ttacttcaca cgactaacag tctttttgtt ttgaggtttt
    30481 ggttggtaat tttttactgc aacttcaagt tttacttgac gctcaatacc aaaaaactgc
    30541 ttcaatccat tagttatttc attttgaatt atttggcatc tgtcaacgat gttgtctgaa
    30601 ggaagaattt taccttctac atgaacgaaa catttatttt ttcgtaaatt tacatgaaca
    30661 gttgggttct tgatcaatct atgatcaaga accaaacttc taacaaaacc ttcgattgcc
    30721 gaattcttta attttaatgt atcgttttta gtttcaagtt ggatttccaa gtaacgttta
    30781 ggataaaaca tcacaactaa aatggataat aaaactaaag ttgatagaac cactgtcccc
    30841 caaaagacat atctagcaag atagaattca actgcggagt tctgtctcca gctaagtagt
    30901 tgaataccta gatcactaac ttgatgataa tctatcaaaa caggaaggaa aattgtcaag
    30961 attaaaatac agaaaataat gaaacatatt ttctttgctt ttgacatata caatcctttc
    31021 gatttaacat ttaaactatt tttcccgtca ttgatttaaa aatagtttgc taactttact
    31081 ggcgaaaagt tcactttcta cctgtaaaga atgacactac agtaatcata atcgctgcac
    31141 ctacaataaa tgggagcaaa gccattccag cgattgatgg cccccaacta cctaaaagag
    31201 attgtcctgc agatgccccg attaaaccag cgaatacatt tgcgatgttt cccatagaac
    31261 tacctttttt agtgatttta cctgccaaga gaccaataag acctccagca ataattaatc
    31321 acaacattgc ctaccctcct tttttatttt aatatcaaaa aatcaatttc tttgattact
    31381 actattatat aactttaata tagaaaagtc aattattttg attattatta ttatataatt
    31441 ttaatattaa aaatcaaatt ctttgattgt tgctattata taatttttaa aattaaaaat
    31501 ataatcttta gacttgaatt tgattctgta ttcacgccct caatagacgg taaaataaga
    31561 aaattgttta tatattgtct ccgtagtgtt attatacgaa ataaaagatt ttaggaaaag
    31621 tcgttatatc atgctatacc tattctttgt ggtataattg caagaggttt aatccgataa
    31681 tttataaaga gagaaagata ttcatgagag atttattatc taaaaaaagt cataggcaat
    31741 tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca gagttattaa
    31801 attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct tttcctgact
    31861 tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat agtgatattg
    31921 aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta gaattcatct
    31981 tctttagtga aggttgtcaa gctgaaagta tttgtaaaga attttatatc agttcatctt
    32041 cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt caatttgaag
    32101 tcagtctgac ccctgttcaa gtcattggaa atgagagaga cattcgttac ttttttgcac
    32161 aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt tcatcagagc
    32221 cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg aatttgtcaa
    32281 cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag tttggtcatt
    32341 ttatggaagt agataaagat tcttttaacg accaaagttt gaatgctttg atgcaggcag
    32401 aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct ttagatgaag
    32461 aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata gatggaagtc
    32521 tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat ctattgagtg
    32581 attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag gataatctga
    32641 tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtccact gagtttattt
    32701 tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca aaatttgttt
    32761 cagatgtaaa aaaagagctt tctcactatt tagagactct tgaggtttgt tctagttcaa
    32821 tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg gtgattaatt
    32881 tgctacaaaa tcagcctaaa ctaaaggttt tggttatgag taattttgat cagtatcatg
    32941 caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa ctagaagttt
    33001 ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat atcattattt
    33061 ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat aatataaaca
    33121 cggtctcact catatatttg ttaaatgcca tgatgtttat tcgattagat gagtaaccaa
    33181 aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag acagaaaaaa
    33241 tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc aaaatgtaca
    33301 tctagattta tagccttcta aaactcttac tttttttgta gaagatacga aaaaagccat
    33361 gaaaccaggc tctataatat ttgtagtggg taaatcccct atggatatta tggagcctat
    33421 tttagggtag aaaaaaagtc ccatatcatc tataatgaaa agcgacaaaa taactcatta
    33481 gaaagaatca tatggaacaa ttacatttta tcacaaaact actcgatatc aaagacccta
    33541 atatccaatt tatggatatc attaataagg atacacacaa ggaaatcatc gccaaactgg
    33601 actacgacgc cccatcttgc cctgagtgtg gaaaccaatt gaagaaatat gactttcaaa
    33661 aaccttctaa aattccttat cttgaaacga ctggtatgcc tactagaatc ctacttagaa
    33721 agcgtcgatt caagtgctat cattgctcga aaatgatggt cgctgagact tctatcgtca
    33781 agaaaaatca ccaaattcct cgtattatca accaaaagat tgcgcaaaag ttgattgaaa
    33841 aaacttctat gaccgatatt gcccatcaac tggccatttc aacttcaact gtcattcgca
    33901 agctcaatga cttccacttt gagtgtaagg ttagaaatct gcctgagatt atgtcttggg
    33961 acgagtatgc cttcactaag ggaaagatga gtttcattgc tcaggacttt gaaaagctca
    34021 atatcatcac tgttcttgag gggagaacgc aagctgtcat tcgagatcac tttcttaaat
    34081 atgatagagc cgtccgctgt caggtgaaaa ttattaccat ggatatgttt agcccttatt
    34141 atgccttggc taaacagctt tttccatgtg ctaaaatcgt tctagatcgc tttcacattg
    34201 tgcaacatct tagccgtgct atgagtcgtg tgcgtgtcca aatcatgaac caattggatc
    34261 gaaaatctca tgaatacaag gctatcaagc gctactggaa actcatccag caagatagtc
    34321 gtaaactgag tgataaacga ttttatcgcc ctacttttcg tatgcacttg accaataaag
    34381 agattctaga caagcttttg agctattcag aagacttgaa acaccactat cagctctatc
    34441 agctcttgct ttttcacttc cagaataagg aaccagagaa atttttcgga cttattgagg
    34501 acaatcttaa gcaggttcat cctatttttc agactgtctt taaaaccttc ctcaaagata
    34561 aagaaaagat tgtcaacgcc cttcaactac actattctaa cgccaaactg gaagcgacca
    34621 ataatctcat caaacttatc aagcgcaatg cctttggttt tcggaacttt gaaaacttca
    34681 aaaaacggat tttcatcgct ctgaacatca aaaaagaaag gacgaaattt gtcctttcta
    34741 gatattagct gacttcaacc cactacagtt gacaaagagc ctgaaaccaa ggcttttctt
    34801 gttgtatgta gatgccccct acagggatcg aacctgtgac ccacggatta agagtccgct
    34861 gctctgccag ctgagctaag gaggcaaaga aaaaagctgt attggtgccg aaacttcacg
    34921 gtttgtattg aacccgcgca attaagcagg tgggcaactc gctctaactg aagctgtttc
    34981 cgtgtgagac ggcctacatg ctgttagaag acttttgttt ccctaataat acaaaaaata
    35041 gtcggtcaac acttaagtgt gaagtcgtac accacagcgt ttctatattt atatgatacc
    35101 actttttcaa aaaaaatcaa gaggaaagtg caattttttg aaaaggattt cagatttttc
    35161 gcaaacggtc gatagcttcc tttctttgag ccaaagcccg ttcatattta ccagtatctt
    35221 ctgcttggaa atagtgatga ttacgaattt tttctggcag atagtcttgc ttgacccaat
    35281 ttccaggata gttgtgtgga tagagatagt cttgggcatt ccccagttcc ttgcttccac
    35341 tgtagtgccc atcacgcagg tgtcgcggaa taggcaagtg ccctgatgtt ttgagatcag
    35401 caagtgcctt atccatagct acataggctg agttggattt tggagaaagg gccaaatcaa
    35461 tcacgacatt ggcaatgaga atgcgggctt ctgggaaccc aatcttctgt gcagcatcca
    35521 gagcagtcac ggtatgaatc tgggcctcag gattggctaa gccgatatct tcataggcga
    35581 taacagtcaa gcgacgagcg agactaggca gatccccagc ctcaatcaag cgggcagcat
    35641 agtggagact ggcatccaca tctgagccac ggatagactt ttgcagggca gatagaacat
    35701 catagtgacc gtctccatcc ttgtccatag tgatgtagct tctctgaaga ctattttcca
    35761 tgatgtctaa ggtgatgtgg cgaatgccct cgtcattctc aggggtagag agaacagcca
    35821 agtccagtga gttaaaggca gagcgaaggt ctccgtttgt agaggttgcg atgaaatcca
    35881 gcgcatcctc atctagttct attggaaaat caaaaccacg ttcagggtta cttagagcta
    35941 tctgcagggc ctctttgacg tcttggttag acagaggttc caactcaaaa atttgaacac
    36001 ggctacgaat ggcaggagtg acggaaaaga aaggattttc agtcgttgct ccaatcatga
    36061 tgaccagtcc actttccaag agaggcaaga ggaagtcttg cttggtctta tctagtcgat
    36121 gaatttcgtc tagcaatagg acgagaccac cagaaaattt agcttcttcc gagatttctt
    36181 gcagtcgctt tttactatca actgtcgcat tgaaagttcg aaaggcatac ttggtcgttc
    36241 cagcgatggc agaggcaata ctggttttgc cgattcccgg agggccatag agaatcatgg
    36301 aggacaggcg gttggcttcc accatgcggc ggatgatttt tccaggtccg accagatgct
    36361 cctgaccgat gacctggtcg atggttttag ggcgcatacg aagcgcgaga ttgtctggca
    36421 tagcagtcct ttctaacgtg gatttgagta gaatgactca tctactatat cttactatgt
    36481 ccattctagc ctattagttg tgatatttca atggttttgt aataatcagg gagtgagata
    36541 gaatcttttt tactatttaa tttaataagg agaggtatca gcatgagaga tttgattttc
    36601 cttaaagctc aaaataggat agttgagcct aaagaagtgg aagtgctgac ttgagaaata
    36661 atattgctaa atgtcattgt atgaactata atgaaaagag aggtgataag caatggaaat
    36721 gatggaacta ccaagtcagg aaattttgat ttttacaaaa caaattcgtc attggattct
    36781 tagtgatcaa gttatttcag ggaaaagaaa acttttcttc cgggaagata ttccaaaaga
    36841 gattttagat ttgtacgaaa acattaaatc taaacttgat tttgcttacc aagaagttta
    36901 ttctaataat gggttgaaaa aatatgaaaa atagaataat tgatgttttt gaagtagtaa
    36961 atcgcatcct tgtaataact gttgaaaatc ctgatttcga agacttgaga gttaatcagt
    37021 ttgtaaaaat tggagataaa aagtatagag tacgcagtgg tcctatgatt cattcaactc
    37081 cgcctcaatc tgtcttagat cgagatactt ttacaattga ctatacagat gatgaattgc
    37141 tcgataaaga agcagttttt actactcatt agaaaaatag gtatgaataa attggcttcc
    37201 cttagaacca catctagggg cttttatgta taatagaata ataagtatca ctcctttaca
    37261 atacgtgtaa cacgtgttat aatggtgttg tcaggaggta aaagcgctat gcctatgaca
    37321 caaaaagaga tggttaaact ccttacggcc catggttgga taaagattag aggcggtaaa
    37381 ggttcccata ttaaaatgga aaagcaaggg gaaagaccta tcacaatccc tcatggtgag
    37441 ctgaataagt acactgaaag agggataaga aagcaagctg ggttgtaaaa ttcagcccct
    37501 gctttttgat atggaggtag tgaaatgtta gttacgtatc cagctttatt ttattatgac
    37561 gacacagacg gaacagaagc gacttatttt gtccatttcc cagattttga atactcagct
    37621 acacaaggag aggggatttc tgaggctttg gctatggggt cggagtggct agggataact
    37681 gttgcagatt tgatagagag tgatggagag ttacctcagc catcagatat caatagcttg
    37741 tctttaattg ataatgatcc ttttaaagat gatgaagatt tcgtgtcaac ctatgacctt
    37801 gataaatctt ttatttctat ggtatctgtt gatgtatcag aatacctagg aagtcaggaa
    37861 cccattaaaa agactttaac cataccaaaa tgggcagata agttgggacg agaaatggga
    37921 cttaactttt ctcagacttt gacagacgct attgcagata agaaagttca aacctaagat
    37981 taagcgtggt atcgtggtaa tagtcaataa aaaagcacgt ccacttgtgc tagttactcg
    38041 cctattgatt ttatagattt attagccctt tcgagggctt tttatattga tttttatgag
    38101 aaatgaagaa atcagacttt taagaaaatc actgatacca agggtttaaa tgaggtaata
    38161 tggtataatt aggacataaa ataattttgt ggtaagatgg tagtatctat tctagcatat
    38221 ttccgagcaa tcggggcgat taaagagtcg catagaaaga ggacaaaatg gcaacatacg
    38281 gatttttaga tgttttagag gaagagttgg acaagaactt tccctttgac tttgagatta
    38341 gctgggacaa acgcaaccat gcggtagaag tgagttttct attggaagcg caaaatgctg
    38401 caggtgtgga gatggtggat gaagacggag aggtttcatc agatgacatt ctttttgagg
    38461 aagcggtcct tttctacaat cctgccaagt caacagtcaa tgaggaagac tatttgactg
    38521 ttattcctta cctgcctaaa aaaggatttt cccgtgaatt tttagcttat tttgcgcttt
    38581 tccttaaaga tactgctgag gttgggctag atgtcctcat ggactttttg gaagacccag
    38641 aagcagagga atttatcatg gaatggaacc aagaagtctt tgaagaagga aaagttggct
    38701 tggaagaggg agaattttat ccttatccaa gatactagga gttggttgga ggtgttatga
    38761 agaaaattgg gacttatttg gtttatgtgc tagcttttgt ctttattatg ctagcttttg
    38821 cttgtggaac aatcgcattt gcagagttgg ggtattccgc agttttagcc tttacttttg
    38881 gttatgcctt cgctcttcta agcatgtatt taatctttat tcttcatgag ctgggtcatg
    38941 ctttttgtgg ctacttgaca ggctatcggc tggtggcttt tggattagga cattttattt
    39001 tgaccaaaaa gtcaggcagg tttcatctta gtagaacagc cattctgaaa aatgttggtg
    39061 ctcaatacat tggtttaaaa gaggatgaaa gcgatcaaag aatcatcctg atgctttcag
    39121 gaggcttgat ggttcatctc ggcttgatat tattggcgat agtgtttgga tttttgacaa
    39181 gaagctggta ttttgcaggg acttggattt ttcttaattt atctttcttc ctaaataaca
    39241 ttttaccagt cggcatcacc gatggagcaa aaatttggga attactacaa caccctgaaa
    39301 ataccaaata cgcctacctg gtattgagac attctgctca aactttgctg gctcctcaag
    39361 aatatgattt gaaagacttt gttcaagcag ttcctgagga tgcacgaggg agttttgcgg
    39421 atggtgtatt aggtatgcaa ggtgaagttt ccattttgga agggaaggaa gaagtagcta
    39481 aacagcagtt tcaagcatta cttgagagga caactactcc gatgatgcag acagttgccc
    39541 aactatccct gcttcatatc gctttgttgg aaggagattt tgagcaagcg gagcaatatg
    39601 ctagtattcg acaggtcaaa tcgtttctgt ctctcaaact gtccaatctt caagtgatac
    39661 aagcctggta tcaattaaag gtgaagaaag atgtagatcg aactcgtaag gctctcaaga
    39721 ttgctagaca gaaaatggat agtagtcgaa tgttgaggga tgagaaaaga tattatgaaa
    39781 actggttagc cgagctggaa aaggaattag ccgaaggagt ctaatatgga aatagagatt
    39841 tctgatttca caggttgcaa gattgctttg ttttgtgggg ataagctttt gactatctta
    39901 cgcgatgata aggcaagcat tccctgggcc aatatgtggg aactgccagg
//
LOCUS       DAVFJR010000016        39707 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVFJR010000016 DAVFJR010000000
VERSION     DAVFJR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.017"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(12..1301)
                     /locus_tag="VU722_001048"
     CDS             complement(12..1301)
                     /locus_tag="VU722_001048"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU1772044.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVT
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGEVANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1379..2047)
                     /locus_tag="VU722_001049"
     CDS             complement(1379..2047)
                     /locus_tag="VU722_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1772045.1"
                     /translation="MSLSMSSADGESLKNEKLSIKYQFLTIYRNLRLVFLKSGQKNFG
                     FMLFAVLLINALGGSLGGIYNIFFLSHSLLNFSYTEALFISQVGALVAVIISSLTGND
                     YFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFFTLYVSGKVQPKISAMLMKN
                     LAPEVLARTSNFLGLLFTLSIPVGTVCFSLVAVWNIQLTWMLFVGISLLAIFLTILNL
                     KNDI"
     gene            complement(2333..2626)
                     /locus_tag="VU722_001050"
     CDS             complement(2333..2626)
                     /locus_tag="VU722_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772046.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALSCSAS"
     gene            complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="VU722_001051"
     CDS             complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="VU722_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU1772047.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFLPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFINAYYFK
                     RVIEEHFYKENETYFRIVYLWAEDLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3792..4133
                     /locus_tag="VU722_001052"
     CDS             3792..4133
                     /locus_tag="VU722_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU1772048.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4191..4271
                     /locus_tag="VU722_001053"
                     /pseudo
     CDS             4191..4271
                     /locus_tag="VU722_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4387..6090)
                     /gene="ilvD"
                     /locus_tag="VU722_001054"
     CDS             complement(4387..6090)
                     /gene="ilvD"
                     /locus_tag="VU722_001054"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU1772049.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6323..7255)
                     /locus_tag="VU722_001055"
     CDS             complement(6323..7255)
                     /locus_tag="VU722_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU1772050.1"
                     /translation="MVRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPRSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQDGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7249..8109)
                     /locus_tag="VU722_001056"
     CDS             complement(7249..8109)
                     /locus_tag="VU722_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU1772051.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFVARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETEW"
     gene            complement(8113..9459)
                     /locus_tag="VU722_001057"
     CDS             complement(8113..9459)
                     /locus_tag="VU722_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1772052.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9472..9756)
                     /locus_tag="VU722_001058"
     CDS             complement(9472..9756)
                     /locus_tag="VU722_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1772053.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            complement(9760..11790)
                     /locus_tag="VU722_001059"
     CDS             complement(9760..11790)
                     /locus_tag="VU722_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU1772054.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTDDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTPKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            11982..12989
                     /locus_tag="VU722_001060"
     CDS             11982..12989
                     /locus_tag="VU722_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU1772055.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSQNIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKFPFLGAKSSNDNDVNLEISKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQSSAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            12992..13192
                     /locus_tag="VU722_001061"
     CDS             12992..13192
                     /locus_tag="VU722_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1772056.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYASETIDEPFEIDI"
     gene            13344..13526
                     /gene="rpmF"
                     /locus_tag="VU722_001062"
     CDS             13344..13526
                     /gene="rpmF"
                     /locus_tag="VU722_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU1772057.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13542..13691
                     /gene="rpmG"
                     /locus_tag="VU722_001063"
     CDS             13542..13691
                     /gene="rpmG"
                     /locus_tag="VU722_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1772058.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(13821..14204)
                     /locus_tag="VU722_001064"
     CDS             complement(13821..14204)
                     /locus_tag="VU722_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772059.1"
                     /translation="MKTKNIEIRRITFSKFEFNTHNTGEVEEDGRASINLNFPDREEG
                     QENQLILIKMEISYPDSQYRVIADIDARYSVLASDLPEDISQDDEFQQALITPMIEKF
                     RLYVGMFSEGAYGAVLIPNLNFNQD"
     gene            complement(14206..14793)
                     /locus_tag="VU722_001065"
     CDS             complement(14206..14793)
                     /locus_tag="VU722_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="HEU1772060.1"
                     /translation="MMKDKEYYLGLNYPILIEKIYDEGELLFTASIKELPGLIVYGES
                     LGEVYDEIELAKADWIEANLEWGRKIKEPFENSLEEYSGKITLRLPKTLHRDVKERSE
                     IEGVSLNQTIVQLINDGLFKQTQNAVEQLTEQFKDMTKKLSQTIAEKVSAPEQHIHQT
                     IIIKNQSEKIQPYKEQNITNNRLQDNKVVSWSIGG"
     gene            complement(14780..15037)
                     /locus_tag="VU722_001066"
     CDS             complement(14780..15037)
                     /locus_tag="VU722_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicA family toxin-antitoxin system"
                     /protein_id="HEU1772061.1"
                     /translation="MGKEKELQKIKNNPKSVTPERLESLCKKYGFMWKQGTNHSITSH
                     ALLEESYPIPRHKPIKPVYMKKVIKMIEKVIELEEGLNDER"
     gene            complement(15155..15475)
                     /locus_tag="VU722_001067"
     CDS             complement(15155..15475)
                     /locus_tag="VU722_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1772062.1"
                     /translation="MYHTEISMFLRGEASQLAKYNKKSGKPYKDIDDLVDFGRPIHIV
                     PHMFRHSFVSVMAEKNVSLNVIREFVGHSEDSREIEKIYLHVMQKGKDKIEQAMIDLA
                     EIIF"
     gene            15631..15837
                     /locus_tag="VU722_001068"
                     /pseudo
     CDS             15631..15837
                     /locus_tag="VU722_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16000..16269)
                     /locus_tag="VU722_001069"
     CDS             complement(16000..16269)
                     /locus_tag="VU722_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772063.1"
                     /translation="MPKTKTLAELADVILWSFDFAIDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREI"
     gene            complement(16656..18536)
                     /locus_tag="VU722_001070"
     CDS             complement(16656..18536)
                     /locus_tag="VU722_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU1772064.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVSVAQSDQASISIKGE
                     DGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSVEELQEIEAYAQQFDMTF
                     VPCIQTLPHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDSMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILDGVVNRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(18530..19399)
                     /locus_tag="VU722_001071"
     CDS             complement(18530..19399)
                     /locus_tag="VU722_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1772065.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWHEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMTINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGIKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(19483..22119)
                     /locus_tag="VU722_001072"
     CDS             complement(19483..22119)
                     /locus_tag="VU722_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU1772066.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVTAFGRGVKQIGFDNQV
                     LEDEQFTSQFSKMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNRWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHNSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVESLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGYEVLENTARYAKILLKHELTVPVSADEKLEEEQKGIIEFMKREAGRSE
                     ELTNIPLETEFTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPGASWENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASGELG
                     DWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVVA
                     TGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPY
                     PVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(22310..23577)
                     /locus_tag="VU722_001073"
                     /pseudo
     CDS             complement(22310..23577)
                     /locus_tag="VU722_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
     gene            23748..25844
                     /locus_tag="VU722_001074"
     CDS             23748..25844
                     /locus_tag="VU722_001074"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU1772067.1"
                     /translation="MKPLLEIIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADKLTVDQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTNAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWNTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYLTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSQPSTS"
     gene            complement(26082..26456)
                     /locus_tag="VU722_001075"
     CDS             complement(26082..26456)
                     /locus_tag="VU722_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface anchored protein"
                     /protein_id="HEU1772068.1"
                     /translation="MIIQESAKLDAETAKEATDLLADAKKVFADPKASQDEVDAMVKR
                     IEDFMAKVSPATDHTSPAKDQAAQTPAVAPATAQAANANQAAANARTVAKELPNTGTA
                     DSTVAMVVAAASALPWSCRPSS"
     gene            complement(26613..28301)
                     /locus_tag="VU722_001076"
     CDS             complement(26613..28301)
                     /locus_tag="VU722_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU1772069.1"
                     /translation="MVREIKPHSPLPSQVQLAYLEDELVAFIHFGPNTFYNQEWGTGQ
                     EDPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSIKVSPWRRG
                     KGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAY
                     GNGGKFAEVWMDGARGEGAQKVNYEFETWFETIRDLQGDCLIFSTEGTSIRWIGNERG
                     YAGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQYPKSL
                     EELVEIYFHSVGRGTPLLLNIPPNKDGLFDAKDVERLYEFAAYRNELYKKDLALGAEI
                     SGSALSVDFACYHLTDGLKTSSGASDVGLPIQLELDLGSPKTFDVIELREDLKLGQRI
                     ATFYVQVEVDDVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYK
                     TPGLSKKEVVQELAFAEKSLAVTKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAY
                     QDEIQVLQFQAGESKKDLSIPTLYFAADKILDFYLNLTVGGQLIDQAHILVETR"
     gene            complement(28303..32032)
                     /locus_tag="VU722_001077"
                     /pseudo
     CDS             complement(28303..32032)
                     /locus_tag="VU722_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001250572.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4982 domain-containing protein"
     gene            complement(32270..37099)
                     /locus_tag="VU722_001078"
     CDS             complement(32270..37099)
                     /locus_tag="VU722_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1772070.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMDAQPVQATE
                     TSSTLISSHYLDEQDLSEKLKSELQWFEENKIEVKEGKEYYFVYRKLATRLPETGLFS
                     NDGTFILGAGLLLLSFTLIKRKRGASYFLVTVFAVGGWGASISAFENLVELQPALVKR
                     VEGQFLPSPERVQGYEFTGYYLVRDSSNKELSVDKVESPALSKKEDGSEPQSKKIVPQ
                     TASHFSSTEDFVQSPQPSYAVEKIVEAPVSKQAPDEIVPIGTKEEIAGNPKVEQPKAE
                     NNSDYKPSPEEGVLNATVEKPELLVTTEEIAFQTIEQEDASLAKGQTKVVQEGVVGER
                     TIYTEVTIVNGEKSSKVIENIVTKEPENKVIAVGTKEEVAPKPTQPVTPEPEEVKPVQ
                     PEKIEKKPIVENETETKPAAGIGQPRPGAEETPGEKQTPDKPEAEPKQPELASPAVGS
                     GREEDQSPAEQKGEENQLENPVEGAKDAGESAPQEPQKQPEQTAPSPEVNPSQGNEPA
                     PAVQPEPSAPQEQSDSQVQPTVPSPVTKEKVLDYKTVYTASPALNYKEQQVEVAGENG
                     KEVTTTSYSFDESTGKIVENTSTKIEKHPVDRVVKVGNVEETTSTTKRGEQFVADESL
                     DKGVKEVRNQGQDEETTTIRVYKVNAQTGDLTEPEVSTKVAKEMQAKITAVGTKPTVQ
                     SQEIPFKTVYKASPDLSYNVQQEETPGEKGRTVSTTKYTVNQETGAISEETTIENIPA
                     KDKIVKVGNVEKIVSPIEITELRKDNPELPKGKEEVEDAGEQGETTVTKTYEVNPETG
                     ELTNPVEKTETTKAMRQKVILVGTKEDKPHLLPINSELENAVNVTEATAEMRNVDLLT
                     NEKLKAQLAPSDIEINRDLFLKRKELRKTNPAITDEEVKEILRKEYLEKLSIKETLDA
                     TKTDLEASLKKVAAHTLSILGDNQQNREKVKGDIEANKEKILLGLSYINRFYNIDFGD
                     TNIRDILAYNPSSFGKKDLTSLDWLTYLGSMSYDELRLTNSPKTFEKYFGKITDKPTL
                     LEFLDYNRTTFTNMDGDTWLKKATKAIVVEKPSKQKPDEKVELYTKLTTPPEKYGAEN
                     LQIESRRQQNVAILLGLVNIKEPSVYAITNIATVTYGNIGTYMDTSLEKTNPVKYKEE
                     LEKVKALIELTATRQAAYVDTLYRITKEENRSKLVTNRVIVDTMKKYTADTSAGIGTT
                     WSKESGPTADKGVKDFMTPLGLYSPSQNVGAEANGVGVRYFIDRVLDDRGSATYSHEM
                     THLLDRTVLFNNHGRRDGTAAEFYARGIFENSYTPEKDTYFNLNFVYDESKKNGFYNK
                     TPDRFKTDADLKSYMHGSFDVLYSLDYLEAEATKQLTAEDKTKYFKKITPIASKGPRA
                     TVTYTNSAVKATHKSEKISEITLAEAEKLTDINSLIDNNILVNRYIINGFYATGDVKA
                     NGYYLVDMFDTIYGVSQNDSGMSGDITFRKQAFELMAALGYYEGFVPYVSNQYKQVAE
                     SENKPLSDTYIFNKILNGKSYAEFKKAQFKERVDRLNQLKPLTIQYEGQQISLTSQKL
                     KELMQKAVLAELAQIKAGNTTAQKFEFIETPVQKLKKAIYKAYLKDSDDFRQSIYNS"
     gene            complement(37417..38301)
                     /locus_tag="VU722_001079"
     CDS             complement(37417..38301)
                     /locus_tag="VU722_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU1772071.1"
                     /translation="MIFLIVCVFLLLIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     MRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38558..39415
                     /locus_tag="VU722_001080"
                     /pseudo
     CDS             38558..39415
                     /locus_tag="VU722_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
BASE COUNT        11525 a         8869 c         7189 g        12124 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataaaatccc agtttttcaa agatttctga gaagttttgg
       61 ctgattgtct caagtgacac ttgcacttct tctcgagttt gattgttctt gaccgtcact
      121 tgtccgcttt cgacttcact ctctcctagg gtgatgaggg tcttagccgc aaagacatcg
      181 gctgacttga attgagcttt gagtttacgg ttgaggtaat cacgctctgc tttgaaacct
      241 tgttggcgaa gggcttgtac caactccaaa gccttgacat ttgccacttc acccaagact
      301 gctatataga catctagggc gttttcgata gggagagcca caccttgctt ttcaagaatg
      361 agaagcaggc gctctacacc aagcccaaaa ccaaatccag cagtttcagg gcctccaaag
      421 taagcaacca aaccatcgta gcgaccaccc gcacagactg tcaagtcatt gccctcaatc
      481 tctgtgataa actcgaaaat ggtgtggttg tagtagtcca gaccacgcac catattggta
      541 tcgatgatgt aatctactcc aagattttcc aacatctgac gcacagcatc aaaatgagct
      601 tggctttctt catcaagaaa gtccaagata gacggcgcat tctctactgt caccttatct
      661 tctttttcct tagaatccaa gacacgaaga ggattttcct ccaagcgacg ttggctatcc
      721 ttagacaagg tctccttgag cggtgtcaaa tagtcaatca aggcttggcg gtaggctgca
      781 cggctctcag gatttccaag agtgttgagg tgcaatttga caccttggat gccgatttct
      841 ttcaagaaat gggctgccat agcgattgtt tccacatcgg tagctggatt gctagagcca
      901 aaacactcaa caccaatctg gtggaattgg cgcaagcgcc ctgcctgtgg acgctcataa
      961 cggaacatag gtcccatata gtagaacttg cttggctttt gcacttctgg ggcgaaaagt
     1021 ttattttcca cataggaacg gacaacgggt gcagttcctt ctggacggag ggtgatatgg
     1081 cggtcaccct tgtcatagaa atcgtacatt tccttggtta caatatctgt tgtatctccg
     1141 acagagcgac tgataacctc gtaatgctca aaaataggcg tgcgcacttc tgcgtagttg
     1201 tagcgtttga aaatttcacg ggcaaagcct tcaacgtact gccacttagc agactcagca
     1261 ggtaaaatat cctgcgttcc ttttggtttt tgtaatttca tagggaatcc tctttaaact
     1321 taatagtctt attttaccat aaataaaggg attaaaacag tgagaaaaaa attaggattt
     1381 agatatcatt tttgagatta agaattgtca aaaaaatagc tagcaaggaa ataccaacaa
     1441 atagcatcca agtcaactgt atattccata cggctactag tgaaaaacaa actgttccca
     1501 caggtatgga taaggtaaac aatagaccta aaaaattact ggtacgagct agaacctctg
     1561 gagctagatt tttcatgagc atggcactaa tctttggttg aactttacca gacacataca
     1621 gagtaaagaa gagaaatagc aaaccaagca cgacttgatt gaataaatta gccaaaccaa
     1681 ctagactaag tcctacggtc gcccacatca tcaatctagg caaggactgc ttcccaaaat
     1741 aatcattgcc cgtaaggcta ctgatgatga ctgctactaa agcaccgact tgactgataa
     1801 ataacgcctc tgtgtaagaa aaattcaaga gagaatggct caaaaagaag atattgtaga
     1861 tgcctcctaa ggaaccaccc aaggcattga taagcaagac agcaaagagc ataaaaccaa
     1921 agtttttctg tccactttta agaaaaacga gacgcaaatt tcgataaatc gttagaaatt
     1981 ggtatttgat agaaagcttc tcatttttta agctttcacc atcagcagat gacattgaca
     2041 ggctcaattt gctttttcct aaaaagagga tagtggctga tactaggaaa aagcaggcat
     2101 tgattcccgc aacgagagaa aaattgttga ccgatagagc taagagccag actccgaaag
     2161 cttgaccacc aatagctgaa atataggtga taaactgtga aaaagaataa gcctccatca
     2221 aatcatcttc agctactttt ccttaataag aggcatacgc aggccacctg caaaatcact
     2281 gatgatatca ctaaggacat tgatcaaaca caggctagaa aaggcaaaga gactagcttg
     2341 ctgaacaact aagggctgct agaaaaaata gaaccgcctg aaacaaaccg ctatagacca
     2401 tccatttgac cttgtccctc gtgtaatctg cccgaatccc tgcaaaaact gtaaagaggg
     2461 tcggaagaat catgacaata ttcgccatag caacagcaaa agatgcttgt gacaaggtcg
     2521 atgcatagac gataaagacc aggttgaaaa tcgaagcacc aaaagcattg aagaagcgtg
     2581 acaaagtcaa gaggcgataa gcttgatttc taaacaatag tttcatagat aatctccctt
     2641 cttgttcgaa gttctacatc aagaatagct ttagtatagc acttatgaat ttgcgaaacg
     2701 attcttttga atatatgcaa caaacaaaat gagcaaaaaa acgatagaac ttttgtaatg
     2761 acctgagaga gggcaacagt tctatcgctt caaatttttt cttggtttgc agatattcaa
     2821 cattcggtcg tatttctata gtattcggca gatttattac agccaagcat ctcaaaaata
     2881 cggacagcat cctccatctt tttctggcct tccttgactc taccttgctt gctatcaagg
     2941 agatcttctg cccacagata aacaattcgg aaataggtct cattttcctt gtagaaatgc
     3001 tcttcgataa cacgtttaaa ataataggca ttgataaatt cttcacactc aatactagct
     3061 aaaaagccat tcaatagtat agtatgaaaa aggtttcgat tgccagacat ttccattaga
     3121 aaatcagatt tacgtaccat ttctcgtaca tatctagtaa aaagagaaac agataaaaat
     3181 ggagaactga ctgaaaataa attgagttca tagattcccc agatctcggt agaaaacaaa
     3241 taatcatgaa ggacttttcc ttcctctgct gttaactcta ccctttcatc tatgctcttc
     3301 atataagact tgatcataat ggcatttaga atatgtttct gtttgttgtg agaatgggca
     3361 tgcttttgat actccctgcg atataagtcc tcaagaggtg ctatattctt tggttccaag
     3421 acatctgtaa tttcttttct caactcagaa tctgtatcat actggaaacc tctcgccaga
     3481 aagaggatct cctccacact ggcagatata ttttccagag caaatagaaa cttttccacc
     3541 gaaagctcac tctgacctgt ttcaaaacgg gacaacatag acggcaaaaa ttgtcctccg
     3601 gttgcttgtc tcagtgagat atttcttgac tctcgtaatt gtctaaagac ttttccaatc
     3661 tgctccatag acttcccctt gattccgtat tttcttcatt ttatcatatt tttcagaaaa
     3721 ttcatcaaaa acttgccaaa ttgtcagaat tatgagaaaa taggggatat ttatcacgtg
     3781 gagggactgc tatgagagac gatatcaaaa tcaatgaccg tgctttggcc ttgcaagacc
     3841 aaattatcga aaaactagag aaagtttttg atacagatgt ggaattggat gtttacaatc
     3901 taggtctgat ttatgaaatc aatctggatg aaacggggct ctgcaagatt gtcatgacct
     3961 tcaccgatac tgcctgtgat tgcgccgaaa gcctgcctat tgaaatcgtg gcaggtctga
     4021 aacaaatcga gggtatcgaa gatatcaagg ttgaagttac ctggtcgcct gcttggaaaa
     4081 tcacacgaat cagtcgctat ggccgtattg cccttggact accacctcgt taagcaggcc
     4141 aatcactttt aaagatgaaa aaagcaagcc gaaaatggct tgctttttga tactcaatga
     4201 aaatcaaagg gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaagtta
     4261 tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg
     4321 aagtcagtaa ccatacctac ggcaaggcga cgttgacgtg atttgaagag attttcgagt
     4381 atgagtttat tttttacctg acttgtccat attccagaag tctgtcacgg ctccgcgtga
     4441 agcagatgat acgatgtggg catatttacc gaggacacca cggctgtaaa gtggtggcaa
     4501 ggttgtttct gccttgcgtt tttcaagttc ttcttcggat acggccatgg aaatttcttt
     4561 ggtatcttgg tcaaccgtaa cgatatcgcc ggtacggaga taggcaattg gtccaccatc
     4621 ctgagcttca ggagcgatat gtccaacaac cagaccataa gtaccaccag agaaacgtcc
     4681 gtccgtcaag agggccacct tatctccctg acctttacca acaatcattg aagaaagtga
     4741 cagcatctca ggcataccag gaccaccttt aggtccaaca aaacgaacaa cgactacatc
     4801 gccatcaacg atttcatctg tcaggacggc ctgaatcgca tcttcttctg agtcaaagac
     4861 cttagctggc ccaacgtgac gacgcacttt aacacctgat accttggcaa ctgcaccgtc
     4921 aggagcaagg ttcccgttca agatgataag cggaccatcc gcacgttttg gattttcaag
     4981 tggcatgata actttttggc ctggagtcaa gtctgcaaag tcagccaagt tttcagctac
     5041 agtcttacca gtacatgtga tgcgatctcc gtgaaggaaa ccatttgcca acaagtactt
     5101 cataaccgca gggacaccac cgacttcgta gaggtcttgg aagacatact gaccagatgg
     5161 tttcaagtcg gccaagtgag gcacacgttc ttgaatcgta ttgaagtcct caagtgacaa
     5221 gtcaacattt gcggcatggg caatggcgag caagtgaaga gtggcgtttg tagaaccacc
     5281 gagagccatc gttacagtga tagcatcttc aaaggcttca cgagtcaaga tatctgatgg
     5341 tttgagacca agttccaaca tcttaacaac agcacgtcct gctgcttcga tatcttcttt
     5401 cttatcagct gattcagctg ggtgagagga tgaccctggc aaactcatcc ctagaacttc
     5461 gatagcagtt gccatggtat tagcagtata cataccacca caaccaccag ggccagggca
     5521 ggcattacat tcaagacgtt tcacgtcctc agctgtcatg tcaccgtggt tccattttcc
     5581 gataccttca aagacagaaa ccaagtcgat atctttacca tcaagatttc ccggtgcaat
     5641 agttccacca taggcgaaaa tggctgggat atccatgttg gcaatagcaa tcatagatcc
     5701 aggcatgttc ttgtcacagc caccgatagc gacaaaggca tcgacattgt gaccactcat
     5761 agccgcctcg atggagtccg cgatgatgtc acgagatgtt agagagaaac gcataccagg
     5821 cgttcccata gcgatcccgt ctgctacggt aatagttcca aactgtacag gccaagcgcc
     5881 tgcagatttg acaccttctt tagccagttt cccgaaatca tgcaagtgaa tgttacatgg
     5941 tgtattttcc gcccaagtcg aaatcactcc cacaatcggt gtttcaaagt ccttatctgt
     6001 cataccagtc gcacgaagca tagcacggtt aggtgattta accatgctgt catagatgct
     6061 actgcggtga cgtttatcta attcagtcat cttatccctc ccatttcagt ttttactatt
     6121 atagcacaat tttcgcatga agaacagaat gaaattcttg aattttcaga aaattctata
     6181 cacatgtgaa atatttaaaa ttaaaaacaa caaagcggat tagtgcactt tctgatgacc
     6241 agaatatgct ttttaatccg ctttctttaa ataacgtact gtaattttta cagaaattct
     6301 ttcagataag tgtatttaac atctatcttg cattataaat ttctagaacc ttctctttta
     6361 tattcgattc actcaaacca tactcattaa gaagataatc cattttccct acttgaccga
     6421 atctttcttg aacacccatc cgatgaattt ttgttattcc atcatcagag aataattcac
     6481 ataaagcact gccaattcca cctatctgat tgtggttttc tacagtaaat atagtttttc
     6541 cacttaacat tgtttttatc tgttctggta tcggtttgat tctaaataaa tctatcacac
     6601 ctactgaata acctaattta gacagttcat ctgcaactcg aatacttgga gcaaccatta
     6661 tgccagaagc aacgattaca agatcttccc cgtgtcttaa ctcaatgtag cctttagaaa
     6721 aatcctctcc atcttgatag acagcctctg gagcttttct aattgttcga atatatttta
     6781 gtccttttaa gtctaatgtc tggttcaata tttcacgaaa ttggatatca tcagtagctt
     6841 caaaaatgat tgatctagga attaaacgta acaagccgat ttcttcaaat ggcatatgtg
     6901 ttccaccatt catctctgca gttactcctg catctgatcc aatcacagtg gcatccaatt
     6961 gtgcgtatcc aagagaaata aataattgat caaatactct tcgtgaagca aaaggaccaa
     7021 atgtatgaag ataaggtcta aacccctgaa tagacaagcc tgctgcaagg ccgaccattt
     7081 ctgcttccat aatcccaaca ttcacataac ggtctccgaa gttcttttca agattattag
     7141 tagccatcga acttgacaaa tcggcttcta agactactat atcagaataa ctttgattag
     7201 cctctaaaag gaaatctcta tatacatgcc gtaattcttt cgtacttctc accattctgt
     7261 ttcctccaat tcctgactta atctttctac aactgaagtt aacatttgtt tctcctctac
     7321 agtagggcga agatgatgat tggatttcat ttcttccagc tcttgaaccc cttgaccttt
     7381 aatagtatct aatacaatgc acttaggtga tgaattattt gactgtttta attggacaat
     7441 cccttcataa atttctctaa tatctgaacc cttgacccta atggattcaa atccaaatgc
     7501 tgaaaatttt tctacgaaat cacctggatt acaaatatcc tttgtaaaac catctaattg
     7561 ttttttgtta tcatcaacaa atacaattaa gttggataac tgttgatgag aagcaaactg
     7621 tatagcctcc caacattgtc cctcatttaa ctcaccatct ccaacaatag cataagtata
     7681 aaagggactc tttcttattc tctgaccata tgcaagtcca gttgcaacac taattccttg
     7741 tcctaaagag cccgttgtca tatctatgcc tggcgttaga tttctatcag gatgagacgg
     7801 taatttggtt ccatttgtat ttaaagaata taagaattct ttgtcaaaga aaccattcaa
     7861 atagagtgta ctgtatagag ctggtcctcc atgacctttt gataatatga aataatctct
     7921 atctcgtgct acaaatattt ctggagtcat tggcattatt tcaccataaa gcactgctaa
     7981 aacttctaca atagacagac ttcctccgta atgtccgaat ccaagatgat tcaatgttct
     8041 aagagtattt aatcggatgt tagtcgcaaa ttttcttaac ccatcttctc tatttttact
     8101 taaaatcatc ccttattcct cctttgcaga tggcttttta ataaaggata ctccaaacat
     8161 aactgctaaa ataagaacaa gaccaatcac aatgcctgct tgtgagccaa attgatttaa
     8221 cattcctaaa ataattcctg atagaccaaa atctgcatct gagaaagttg agccttggaa
     8281 accaagtcct cccaaaactg gcattaaaaa gactggaaga aaactgatta aaataccttg
     8341 taaaaatgct ccaatagtgg ctccacgaac accaccagat gcattcccaa tgacacctgc
     8401 agtcgctcca cagaagaaat gaggtacaac gcctggtaag ataacaaccg ttcctgaagc
     8461 aatcataatt gccatactta ctaaaccacc aacaaaacta gagataaatc caattagaac
     8521 tgcattaggt gcataagtat aaacaatcgg acaatccaaa gcaggtttgg aattaggtac
     8581 aagacgctct gaaatacctt taaaggctgg aacaatttca cccaaaataa ggcgaacacc
     8641 tgctaaaata acaaataccc ctgctgcaaa ttgacctgct aattgtaaag cataaactag
     8701 accacttgta ccactactga tttctttttc tatatattct gaccctgcaa agatagctac
     8761 aataatgtaa ataactgcca tggataaagt aatactaaca gtactatcac gtaaaaaagc
     8821 taaactcttt ggaaatttaa tgtcctctgt tgattttgat ttgtcaccga taaggctacc
     8881 agtaaaacca ctcaaccaat atcccaaaga actgaaatga cctaaagcca ccttgtcatt
     8941 tccagttaat tgaaccatat atttttgcac aaatgctggg gaaatactca taataatacc
     9001 gagtgctaat cctcctagta agatgagagg caagctagta aagccagcaa ctgataaaat
     9061 aaccgcaatc atacatgcca tatatagagt gtggtgccct gttaaaaaga tatatttaaa
     9121 tcgagtaaaa cgagcgatta agatattgaa caccatgcct gcaaacataa tcattgcagt
     9181 agctgagcca tatgttgtta aagctacagc tacaattgct tcattattcg gaacaactcc
     9241 agataaatga aaagcatgtt caaacatggt accaaatgga ttcaaagaat tttgtacaat
     9301 tcctgcacca ccagatacaa ctaagaaacc aacaaaggtc ttaattccac ctttaataat
     9361 atcaggtaat ttcttcttct gaagaactaa tcctaagatg gcaattaaag ctactaaaat
     9421 agctggtgta ctaacaatat ccaatatgaa cttcatcatg acgctagcct cctatataag
     9481 tcctttttct tcacaaattt tagtaattaa ttctcgtagt tcgtccatat caataatact
     9541 atttaagata cgaacatctc caagatgact agctgaatca gctagatcac gaccaacaat
     9601 ccaaatatca gctgcatttg gatctgctcc acctaaatca taatgttcaa cttctacatc
     9661 cgaaacattc aaatcactca atacagattc aatattcatc tgtaccataa aacttgaacc
     9721 taatcctgaa ccacaagctg taccaatttt caacattatc taatcctcct gtttaattat
     9781 cattttaatg tcatcatagt tttttgatga tattaaagtt tgaacatgat ttttatctct
     9841 taaaattgtt gttaaatgtg acaaagcctt taaatgactc tcattatcaa tggctgcaat
     9901 acaaatcaac aatcttacct cttgttctgg attatccaat aaataaatcg gttcttccaa
     9961 aactaacatt gacattccta tttcattcac accttcatct ggccgagcgt gaggaattgc
    10021 tactcccttc cctaaattaa taaaaggtcc aaactcttct actttttgaa tcattgcctc
    10081 agggtagttc tcagttatct tatcttgatc caaaagcggt ttagctgcta aacgaatcgc
    10141 ctccttccat cctaattttt gcgaactaac ctgataggtt tctttggtaa taagttgttc
    10201 tagcactggt acaatttcct ttctatcatt tttttgataa agataattct ttaacgccaa
    10261 tcttaattcc aattcttgtg taataattcc atatcttttg acaatattca ggatttgttc
    10321 aatctcaaaa tctccatact ctaaattcgg aaaatctttt aacactagtt ctactagttg
    10381 tattgcttgc tcttcagtca tcataaccga aactagataa tttggctttt ctgtctccac
    10441 ctttatggta gaaaaaacca tatcatagtc actactagct ttcacctgta aatcatcaat
    10501 ctttggggtt cctataaact caatttgagg aaataatgct aatagattct cttttaacat
    10561 caatgaagaa ctaacaccat taggacaaat gattgctgct ttataccatt tttgaggcaa
    10621 agtatctgct ttctttaaat aacctccgaa atggataaca aaatatgctg tttcactatc
    10681 aggtatggga ttgtcaatag cgtccatcaa gggcatcaaa gaatctttga ctaattcaaa
    10741 taaatcagga taatgttctt taacatgcaa tacatattca tttgaactag gtaggccgaa
    10801 ctttaatcta tagtaagccg gtataaggtg gcggcgaaga ttttctctca atccttccct
    10861 ttgtttaaaa tgtaacaaag aaatatcttc cattctactt ataatagcct ctgttaattg
    10921 attaaagtaa accggagcaa catctacttc accttcaaag caacttgata ataaaactgt
    10981 gatatagcga taatcatcct cagaaaacac cgtatctata attcccaaat caaccactgt
    11041 atccaataaa atagtggtta tatcttgaat aacaggagat actaatgtct ctgaaagaca
    11101 tactctttca acatcccttt gatacctaca cagaatgaat actaaaccga aaaggcaaac
    11161 ttttaattga ttaacaatag gtactagctg tagcttctca taataatctt taactacctg
    11221 atttatcaaa tcatcagtta atgaataccc ccaactggat aaaacataat ccaaacccca
    11281 aatccctatg gaggattcca gcaactcact aaccatttga aaagctaaac ggtgcttatt
    11341 ccactctgaa ccgtgtaaag tataaccttt tgctctactg taccctagct ccaaatcatt
    11401 atctaacata atctttctta atgattgaat atcagataag gttgtattct tacttacttt
    11461 caaaaagtct tggtaatgat tattcgatat aaaatctaat cggcaaaaag tgtaaagata
    11521 gattaaagct aagcgagtcg actttggtaa aaccaattca tccgacttaa taatatctgt
    11581 caaagactgc ttcgtacgat ttgataaact atagcgacct tgctttttat ccagcactat
    11641 ccccttatta gctagataag gcactaaata atctattcct tctttgactt cctttatagg
    11701 taagctcacc ttaacagata attcatataa tgatagctca caatgatcca tcaaagtcat
    11761 caaaataact agtgctctat aatcaaacat ttctcttcct ttctaactac aattatagtg
    11821 taaaagttat aagaataaaa gagtatttga gcacaatata atctcacctt ttaaaagaaa
    11881 ttattgggct gaaacttttt agtgattatt tttcaacttt ctattgactt tataaattaa
    11941 agtgatatca tttagatatc aaataatggg aggtcattct tatgactgaa aaactaatca
    12001 attcaaaacc aaatggtgta ttcgcattga ttctcattga gttgacgctc gtacttggtg
    12061 tctttatatt tataatgggg gttggttctc aaaatatttt tggtattatt atcggacctt
    12121 tactaatcgt aattgcaggt ctagctcatg ctggtttaaa agttgtcaaa cctcaggaag
    12181 ctctggttct gacactcttt ggtaattata caggtaccat caaagaacct ggtttttact
    12241 ttgtcaatcc cttcagcgta gcagtcaacc ctgcaaacca cactcgactt ggacaaagtg
    12301 gtgatgttag cacaaaattt ccttttttag gagctaaatc atcaaatgac aatgatgtaa
    12361 atcttgaaat tagcaaaaaa cacatttccc tcaaagtcat gaccttgagc aattctcgtc
    12421 aaaaaatcaa tgattgctta ggaaaccctg tagaaatcgg tatcgcggta acttggagag
    12481 ttgtcgatac cgctaaggca gtcttcaacg ttgataacta caaagaatat ctttcattgc
    12541 aatgtgatag cgccctccgt aatattgtcc gtatctaccc ttacgatgta tctcctaatg
    12601 tggatactac gggtgacggg caagcagatg aaggtagtct ccgtggctct agcgaaattg
    12661 ttgctaaccg tattcgtgag gaaattcaaa gtcgcgtaga agatgctggc ttggaaatcc
    12721 ttgaagcacg tatcacttac ctagcttatg ctccagaaat tgctgccgtt atgcttcaac
    12781 gccaacaatc atctgccatt attgatgcac ggaagatgat tgtagatggt gctgtaggaa
    12841 tggttgaaat ggcactagaa cggctcaatg aaggggaatt ggtagaactt gacgaagaac
    12901 gaaaagctgc catggtttca aatctccttg tcgttctttg tggcaatcat gatgcacaac
    12961 caattgtcaa cacaggaagt ctttactaaa gatggctgaa gctaaaaaaa agcagatccc
    13021 ccttcgactc tcaacaaagt tatacgctgc actcgcatca tgggcagaag acgactttcg
    13081 ttcagtcaat gggcaaatcg aatatctcct cacagagtgt gtcaagcaac ggaagaaaga
    13141 cggaaaatac gcatcagaaa ccattgacga accatttgag attgatattt aacatcttct
    13201 cctgtctgac aagtcggaca ggagaatttt ttcatctttt tttgtcaagt aactttactt
    13261 tacaaacaaa atgtgttatc ctagtatggt tgatgaaaat cagtagattg aatcgaatat
    13321 aaatacctaa aggagaaatc aaaatggcag tacctgcacg tcgcacttca aaagcgaaga
    13381 aaaacaaacg tcgtacacac tacaaagtaa cagctccatc tgtaaacttt gacgaaacta
    13441 ctggagatta ctcacgttct caccgtgtat cacttaaagg atactacaaa ggacgtaaaa
    13501 tcgctaaagc tgcatcagct gaataataga agggagatac catgcgcgta aatattacac
    13561 ttgaacacaa agaatctggt gaacgcttgt accttacttc taaaaacaaa cgtaacactc
    13621 cagaccgcct tcaattgaag aaatactcac caaaacttcg caaacacgtt gtgtttacag
    13681 aagttaaata attgagtaaa ccaaaagccc ttgaaaccaa catttcaaag gcttttttct
    13741 ttttgtttta ggaaaataac tgaattttaa ctgattaaat attccgtaat gatatatgaa
    13801 taataaaaaa cggataactt ctagtcttga ttaaagttta aatttggtat cagaacagct
    13861 ccgtatgccc cttcagaaaa cataccaaca tataatctaa acttctctat cattggtgta
    13921 ataagtgctt gttgaaattc atcatcctgc gaaatatctt ctggtaaatc tgaagctaag
    13981 accgaatatc tggcatcaat gtcagcaata actcgatact gactatctgg gtatgaaatt
    14041 tccatcttta tcagaataag ttgattctct tgtccttcct ctctgtcagg aaaatttaaa
    14101 ttaatcgaag ctcttccatc ttcttcaact tctccagtgt tatgagtatt aaattcaaat
    14161 ttactaaatg ttattcttct tatctcaata ttttttgtct tcattttaac ctccaataga
    14221 ccatgaaact actttattat cttggagtct attattagta atattctgct ctttataagg
    14281 ttgtattttt tcagattgat tttttataat gattgtttgg tgaatatgtt gctctggtgc
    14341 agaaaccttt tcagcaatgg tttgactaag ttttttagtc atatctttaa attgctctgt
    14401 tagctgttca acagcatttt gagtttgttt gaataacccg tcattaatca attgtactat
    14461 agtttgattt aagctgactc cttcaatttc agagcgttct ttaacatctc tatgtaaggt
    14521 tttaggtaat cttagcgtta tttttccact atactcttcc agagagttct caaaaggttc
    14581 tttaattttt ctcccccact caaggttggc ctcaatccag tctgctttag ctaattcaat
    14641 ctcatcataa acttctccta aagattcacc ataaacgatt aatcctggta actctttaat
    14701 agaggcagta aacaataatt caccctcgtc ataaattttt tcaattaaaa tcggatagtt
    14761 caatccaaga taatattctt tatctttcat catttaaacc ctcctccaat tctatcactt
    14821 tctcaatcat ttttataact ttcttcatat aaactggctt tatcggctta tgtcgcggta
    14881 ttggatagct ttcctccaat aaagcatgag aggttattga atgattggtt ccttgcttcc
    14941 acataaaacc atatttttta cacagagatt ctaagcgttc aggggtaaca gatttggggt
    15001 tattttttat tttttgcaac tctttttcct tgcccatgat gtacctcatt tacagcgaca
    15061 ctatatatgg tgtcacaata attatatccc aaaaattcgc taatttcaag gatttctttt
    15121 aattttaata aaatatctga atttcataag ataattaaaa aattatttca gccaaatcta
    15181 tcatagcttg ttcaatctta tcttttccct tttgcataac atgaaggtag attttttcta
    15241 tctctctact atcttctgaa tgtcctacaa attctcgaat aacgtttagg cttacattct
    15301 tctctgccat aactgaaaca aagctatgtc gaaacatgtg aggaactata tgaataggtc
    15361 taccaaaatc tactaagtca tcaatatctt tataaggttt tccgcttttc ttattatact
    15421 ttgccaactg gctagcttca cctcttaaga acattgaaat ttctgtatgg tacattgggc
    15481 taccttgttg atttttgcct ttaacgtaga ttctagtaaa tatatagccc atatctttat
    15541 aagttggata aataatacca ttaaggaaag tgcaagggcg catttgattg aaagccaggg
    15601 agtgaaggca gtaaagtcaa tgccttttgc cgtaaatcca gcaaactcaa gccgctacca
    15661 gctgaagata aagcctataa ccatgcgcta tccaaggaga gaagcaaggt tgagaacatc
    15721 tttgccaaag taaaaacgtt taaaatatct tcaacaacct atcgaaatca tcgtaaacgc
    15781 ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg attctagttt
    15841 tgcaggaagt ctattgaaat actaatccta cacagactga ttccaattgt tttttagatt
    15901 tcaattttac cattcttcat agtcaaaacc atcataatct ggatattgtt ctagcgacgt
    15961 tccaaccgaa cgtacgagat aagcttcttc gtcctctgtc tagatttctc tcagcacttg
    16021 gcattcaaaa cgccattcat caccgaagtc gaaaataaac ttaaattttt gtttgacact
    16081 taggctatcc agatagacat tttctgtgta acgttcttca acatcgtcac taacaaagct
    16141 aagaaagtaa gaatctgcat gactccactc aacattatcc atgaaaaatg cgtgagcatg
    16201 atcaattgca aaatcaaaac tccataaaat cacatctgct agttccgcta acgtttttgt
    16261 ttttggaatc tatatatgtc ggtagcaacc ttttttaaat ttgacggaaa tgatccaagc
    16321 ttctacagat gctggctttt cagcttctat ttcttgtttt actaatttta agtgtagcat
    16381 aatacctcca attgctcatc gatagaattg ctcttaggaa acattcactt tctgctattt
    16441 tatcataagt ttgtctaact gtagcatttg aaaccagata attcttctgt ttcacgcgaa
    16501 acaccctgcg ccaagcaagg tattcttgtt tttatactca atgaaaatca aagagcaaac
    16561 taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg gaagctgacg
    16621 tggtttgaag agattttcga agagtatgaa gagtattaag tcgtataaat cgtcgacgct
    16681 gtcgcaatgg tatgccactg gttagctgta gttgctgcga agtccttgtc tgcgtagaag
    16741 tcagtaaatg gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg gccagccaga
    16801 taaacctcga tacggctttc tgctcgtttg atgcgttgca agagtccgcc catacggatg
    16861 tcaactgtat ccaaaccaaa gaccttgttt tctttcagcc attggtgact aaagagggca
    16921 tggaagtctt caatttggct tctaagttct ggtaattctt gtctggcgat ttgttgtaaa
    16981 ctttctttat catccgcttg gtaggcctga cgaatgcgtc gtcccacatc tactttgcta
    17041 cttaaaatag cattcaactg ggcctgagtt tcaaagagat aagcatagtt tccagctttt
    17101 tctttaatgt cagcaatagt tcccgccgcc tgagcgaagt gtggcttgtc ctgttcaggt
    17161 gtcatgtgtc ggtcaagtat cggacagaga acatcctgat aaaagacata gcggttggga
    17221 ttgatgccac tgagattacc tggtaggtct ggtaagaggt tggcaaggtc aatctgcata
    17281 aaatcctcaa ccgttagacc agtattggtc ttgaaatgcg cagacaaact atctaggtca
    17341 ttgcgatagc tgagttctgc ccagatttgc aagcttggta ggatagagaa ctgggcagtt
    17401 tcaccaccat tgtctcccca acccgttacg atgacttctt taatctgatt ggcacggcag
    17461 gctttattag cctcgatagc tactagacgg ctaaaatggt tgtgaggtgt aaagccaatc
    17521 cacttccaag ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg attgcggaaa
    17581 ttacggttgt atttttcctc gctatcctga taataatccc agtaaaccag agtcacacgg
    17641 tctttgagac ggtctaggta gacacgagtt tcctctggaa tttccacatc acggtcgtac
    17701 tggccatccg ctgacatgag tttgaagaac atatcactcc acatctggca gtggaaacca
    17761 tatttgtcag caatatccag cacgcgctcc aagtgttggc acatgaggag actacgattc
    17821 acaacaccgt ccagaatcag gtagcgtccc aaaccaacca agtgggcttc atccatcccg
    17881 atattgacct tgcgagtctt cagtttagac aacgtggcaa acatgctatc aatcaggtca
    17941 taaacctttt cttcgccaat gagaagaatg tcctctacat cacggagctc ttgcacttcc
    18001 ttgacacccc atttgacgaa ggctgacaaa tggggcaagg tctggatgca aggcacaaag
    18061 gtcatgtcaa actgttgggc ataggcttcg atttcctgca actcctcaac tgaataagct
    18121 ccacggaaat agccaaagta aggttgccct tcaatctggt aagtgtcttc catgtaaagc
    18181 tcaaaggttg agtagcccat gagagccaat atctcaatca tctgcttggc agaagcgaca
    18241 tttagcaccg catttcgaga acagtcaacc atgtaagcca aatcttcgta agctgcttgt
    18301 tcctcaatct ctactttatc agcttctgct agaactgtta ccaacaagga caaggcacga
    18361 taaagttggt gaggtttgcg gtaggtcaat tgatagtgac catcctcacc cttgatagag
    18421 atagaggctt ggtcagactg agcgactgac acctcaacat ctggcagaga aatgtgacct
    18481 tttaaaacct caatagcttg cgtttgtttg ggactaagtc ctgtaaatct taccattgct
    18541 tttcctcctg tagccagttg acaagggcac cgtagagatt ggcatctgca tgataggtgc
    18601 aggcctggat aactggtgcg accgtgtatt cttcgtaggt atcgacaaag ttatcaacag
    18661 ccttcttaat accttggata aaatctggat tttgactgat agagccaccc agactgatga
    18721 catctggatc gatcagatac tggatattga gcaagccttg cgccagattg cggttcatgc
    18781 gctcaatggc ttcttgacaa agagcattac cagctgcggc ctcttggtaa atcttgcgac
    18841 cgtcccaatc agtatgacca gatttttcaa tcacatatcg taccatattc ccagttgacg
    18901 ctagttgcga ccagttatta agtttttcag caggggcaag ggttgtcatg tagccaaatt
    18961 ctccacccag accgtggcga cctcgatgaa gtctaccatt gatagtcatg gctccaccaa
    19021 ttcctgtccc aatcacgaca caggctgcat tttcaagctc tggatgagct agtagttcac
    19081 tgagtccaac gcagttggca tcattttcta aatggacagg tagctgataa gagctaagcg
    19141 cctcatgcca agaaaagcca tggatgtagg gcaccgcact gaagccatca atcacacctg
    19201 tctcttgatt gactgcacct ggaacactca tagcaatccc actgtaatcc tgttctgaca
    19261 agcgttgatc tagccacgct agtaaatcct ccaagttttc aggcgttgaa atacttgtct
    19321 tatccagtat tttcccatca ggagtcagac tggcaaactt aatcccagtc cctccgatat
    19381 caatcgttgc aatggtcatt gtttttacca taaaaagggg cgaatcagca gttagttctt
    19441 actttttcgc ccctcctttc ttttgatgtt tactttttga aattaaattt cttctttttt
    19501 gatgaattct gtacgaatct cttgtggagc caatagtcct gaatgaactg gatatggtcg
    19561 ctcaagtaag tcaagaatgg tttgttgatg ttctgatatg cgcacatttt cttgactcat
    19621 attatagtaa cggaggacat agccttcttc attttccgcc actttaaagg ctgttggaca
    19681 aacttgcggt atgctgagaa cagaatggct caagaggcta ccagtcgcaa ccacgcttcc
    19741 ttcctgtcta gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg cacgacgata
    19801 ggctgagaag cgttcttggg cttggtggca ttcaagtgca aactcgactt caaactcacg
    19861 caagcattgt gcttctggcg ttgggaagta gccccagtca cctagctcac ctgatgcacg
    19921 caaaatggtc acggcaatgg tgttatcccc aaggatttcg tattcattca atcccttatt
    19981 ggatacagtc actccttttt catcgtcata cagactgaca aaagcttgtt gatgttgagg
    20041 attttcccat gaagctcctg gtttgtttgg tcgtgtcacc acctcataga tgctttcaga
    20101 atcattgctt ggacgcgtgt tatgagtctt gaccaagaga cggatacggt gatccttggc
    20161 agtgttagta aagcgagtct tgaagcggat ttgtggattg tcaacaaaga cagtaaactc
    20221 agtttccaga ggaatgtttg tcaattcttc tgaccgtcca gcctcacgct tcataaactc
    20281 gatgatacct ttttgctctt cttctagctt ttcatctgca ctgacaggca cggtcaattc
    20341 atgtttgagc aaaatcttag catagcgagc tgtgttttcc aagacctcgt agcccttaag
    20401 ctctgcaaag attggctctg ttccttttgg ttggaaatag atatactcgt ttccgatgtc
    20461 cccacggtct tcaaagcgga taaagtcttc ataagcttcg tgagttgtct tgtcataaac
    20521 tgtgatattg tcatctacac tcaccgttac gaatggtgta tcaatcactc cgttttggta
    20581 aataccctca cggtgttctt gttttccttc cagcaattgg aaggttgtcc aagaaagcgg
    20641 tgctaggtga actggaatgg tcacgcgcac ttgtcgagca atacgagctt ggcggaactt
    20701 atcttttggt aaatcgtact caaaattagc tccgaggtct tcgattgtag cctctacagg
    20761 acgaccatcc aagtcctcca cacggtagct tggcaagata agagcagcca tctttttgta
    20821 gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc acatcaatca ctgtgctgac
    20881 agtatcgacc ttatcatgca agcctgtgtt aatgacagta aagagatagt cactttgagc
    20941 cttatccgta gcaattttac ccttccactc gttgagcaag ttacttttaa caaagtttcc
    21001 tacttggttg accttggcaa aacgcgtttc catctcgcgg tgaacttcgt ccacgctaca
    21061 gccacagata ctatcatgtg gcgcattctg caaaagtgtt ttccaagcat aggtcaactg
    21121 gtccttgtgg ttgtgtccac cagtgataat agtcaaggat tctaccactt gctctaggag
    21181 gttgctattt tcttggaagg cttgttttag gtaaatgcga gatgaagaag tgttggcaag
    21241 tgtgtaccag ccatctgttt cctgactggt caactcgcct gtaacagttg ataagtgttc
    21301 aggaagcgca ccttctacag cttgaacata ttcatcaaaa gaattatgaa caaagattac
    21361 atccgggaag agttcatttg ccacacgaat ggcttcgctc agatttttct gtacaggctg
    21421 gtggtcacag ccgttcatca tcaaccatcg gttggtcgaa gcgtaggcac gcacatctga
    21481 caatttttgt ttccagaagg tcaaggcctc atctttgtca actggaattt cattcccgtt
    21541 actgtaccag ttggcaaaga gaatacctaa aacacgacta ccatccacac cctgccagta
    21601 catttttgaa aactgggatg taaactgctc atcttcaagg acttggttgt caaatccaat
    21661 ctgcttcaca ccacgaccaa aggcggtcac gtgaatgcct gatttttgaa gaatttgagg
    21721 cgcttgtccc atatttccaa aggtatctgg aaagtagcca atctgagttg atttacccca
    21781 tttggcagct tcttgttgac caatcaaggt attgcggaca ttggcttcac ttgaaatcaa
    21841 ataatcatcc tgcaagatgt aaaagggacc aattttaagc ttgccctcgt caatgtagcg
    21901 ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag tcgtcaagga caatagtttg
    21961 tccatccaag tggaaactct tgaactcagg gtcattttca aagagatcaa agagattgtc
    22021 aaacaattcc accaactgca tacgatggct ttcaaaaggc aagtaccact cacggtccca
    22081 gtgactatgt gagataatat gtacaacaac attttccatg aagtaaaacc tcattctaaa
    22141 tttaaatttt aacgttttaa atgtaaactt gtgattctga taagaatcgg ttgagctaat
    22201 actcaacgaa aatcaaagtg caaactagga agctagccgc aggttgctca aagcactgct
    22261 ttgaggttgt agataaagct gacgttgttt gagagatttt cgaagagtat tagcgaatat
    22321 ccaagtaatc caagaccaac tcacagaaca tcatgttagc ccaggagaac cattcacgag
    22381 agtagagggt cggatcatct acgtggaagc tttcgtgcat gacacctgta ccaccatcgc
    22441 aggcaaccag ctgatccagc aagaattttt tctctgcctt atctcttgtt gtcaatcctt
    22501 ggatagaaag ggcgattggc cagatatagc gatagaaggt atgagaactt ccgagaccgc
    22561 tagcgtattc tccttggtag aagtatggat tttcagagct caaaatggta cgacgagtag
    22621 cttgatacac ttcatcatcg accgaacagt agcccagata gggcgcagct agtagacttg
    22681 gtacatttgg atcatccatg atgctggcat ttcctaggcc atccacttca aaggcataaa
    22741 tcttttcacc cttactgttg gtggtgtaag catagttttc aattccttct tggatctcat
    22801 cctgaagacg cttggcatca gcaataacac tctggctatc agctaggttt aatgctgcga
    22861 agatttcttg cacataaccc aagactacta cagcaaacat atttgacgga atcaagtaac
    22921 tatactggca acagtcatca ctcggacgaa aagctgacca agtcatacct gtcactgcaa
    22981 agtcaggtcc aaagccatca tttactaagg tgccgtatct cggacaaaac gataaggaga
    23041 gttcttgtgg tcttgttcaa ctgtccatag atggagaatt tccttagtcg ctgcgacaaa
    23101 agtttcatca aactgactag tctcgccagt ctctttccag aggagataag ccaactgcaa
    23161 gggatagcaa agtgaatcca cctcatactt gcgctcccag atccagccgt taaggtctgt
    23221 gtggtcagtc tcgtggtgcc ctttacagtt ctcctcaatg ttgaaggagt tagcataggg
    23281 atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct gacgcaggag
    23341 ggcatctctt ttagctacat gaaggtaggg tctgagttag gctgtcgaat ctcgaagcca
    23401 catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga tttcaaccgt
    23461 attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg gatggtcctt
    23521 agcccgctct gctacttcat ctagccattc tctaacaatt tctttcgaat aaatcatcgt
    23581 gcaatttcct ctttcaaaca agtttcattt tcagtatata gcttttgaga cagaaaatac
    23641 atacacaaat gatagtcatt tttctacaaa atagttatct ttaaaactcc ttttctaaag
    23701 gtcctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg aaaccactac
    23761 ttgaaatcat cgatacccgc tttggaacta ccaacaagca tgccttttct cggggaaata
    23821 ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag accagtgacc
    23881 aggatggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt cgcttaactc
    23941 accagcccag tccttggatt ggggactact cttggctcct tctgacacct gtcacaggtc
    24001 agcttggggg agacagtctc tttcaccgcc aatcttccta tgatagggat aaggcctctt
    24061 tccaacctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc cagctcacac
    24121 cgacttgcta cggtgcttct attcgtttga agcaaaagca aggcaaagcc ctctccctct
    24181 atcttcacgc agcagataaa ctgacagtag atcaagtaga taagcggact cttgccctgc
    24241 gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact gccctgcaaa
    24301 tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt gacttagcaa
    24361 gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa gctctaatca
    24421 atctacctca agaagatttt gatagctgta aaacaaatgc ccaagcggat tgggaaaatc
    24481 tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc tttgaccact
    24541 gcctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag tcagggcaag
    24601 ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt agcaacaatg
    24661 gtttctggaa taccttccgc accaccttcc ccctctttgc cctcatcata ccggagcact
    24721 atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc cttccaaaat
    24781 ggctggctcc agatgaacgg ggtatgatgc caggtacact tttagacggt attatcgcag
    24841 atagcgcctg caaggacatg acccctgacc tagaaggaga actcttccaa gccatgctcg
    24901 aaacagccag caaagccgac cctctcggaa tcaatggccg ccacggacta gcccaatacc
    24961 aagaactagg ttacctctct accgaccacc acgaaagtgt tagccatact ctagactatg
    25021 cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata gaaatcgctg
    25081 aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag acaggttaca
    25141 tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat agttgggggc
    25201 gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac gacatccctg
    25261 gcttaatcca acttatgggt ggaaaagaaa cctttagcaa ctatcttttg aaaacctgtc
    25321 aagatgctcc cctctttgaa acaacaggct atggttacga aattcacgaa atgagcgaga
    25381 tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc cacattcctt
    25441 atctattccg ctacagcgat taccctgact acactgccct tcttatcaag acgctccgtc
    25501 agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat ggtagtctct
    25561 ctgcttggta catctggtca gctctcggat tttatctaac ctgtccagga aaaccaagct
    25621 atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa gaagataaat
    25681 ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa gaatgccgac
    25741 tggacaaaac actcgtatca actattcaac accaagacct cttaaaagct gaacaactaa
    25801 ctttcaccct cagctggtta ccaagtcagc cgtcaacttc ctgaaatgca aaaatctcct
    25861 agcaggcttt cctgctagga gattttctta tgagaggtat ttgtttaata ctcaatgaaa
    25921 atcaaagagc aaactaggaa gctagccgta gactgtactt gagtacggca aggcgaagct
    25981 aacgcggttt gaagagattt tcgaagagtt taagctttaa aaatcggatt tattattcga
    26041 taattatcaa acaatctacc aattaagctt cttcgtcttc tttacgacga cggcctgcaa
    26101 gaccaaggta aggcacttgc ggctgctact accatagcta cagtagaatc tgctgtacct
    26161 gtatttggca actctttagc gactgtacgc gcgtttgctg ctgcttggtt ggcatttgct
    26221 gcttgagcag tagctggagc tacagctggt gtttgagcag cttggtcctt agctgggctt
    26281 gtatggtcag ttgctggaga aactttagcc atgaagtctt cgatacgttt aaccattgca
    26341 tccacttcat cttggcttgc tttcggatct gcaaatactt tcttagcgtc tgccaataag
    26401 tcagtcgctt cttttgcagt ttctgcatca agcttagctg attcttggat aatcaattca
    26461 tctaattgat ggatagcacc ttaaacacaa gaaaggtaca gagatgcaaa accattatac
    26521 tacaaaaggc aaacatttga caatcgatag ccgtcgctta atcgaaagat ggaaaaaaga
    26581 aatgaattat gaagatattt tatgaagata ttttatctcg tttcaactaa aatatgagct
    26641 tgatcaatca gctgtccacc aacagtcagg ttcagataaa aatccaagat cttgtcggca
    26701 gcaaaataca gagttggtat gctcaagtct tttttgcttt cccctgcttg gaattgaagg
    26761 acttgaatct cgtcctgata ggcgacacca tggacacctg tccccggttg aatcgaaatc
    26821 ttagcctcta aagaggagct actttcacta cgttcaatcc taaaatgaag agtctctccc
    26881 tttgtaacag ctaggctttt ttctgcaaat gctagttcct gaacaacttc tttttttgat
    26941 aatccaggag ttttataaag ggaaatcttg gtcaatacag gaatagattg tgcctctgta
    27001 atcatcacgc gcaccttctg tgcctctact agcggacctc gcaagaggcg cttatgacca
    27061 actgtgaagc ccctgccgaa ttcttgccag acgtcatcca cctctacttg cacataaaaa
    27121 gtagcgattc gttgccctag cttcaaatct tctcttaact caattacatc aaaagtttta
    27181 ggagaaccta agtcgagttc taactggatt ggcaagccta catcgcttgc cccagagcta
    27241 gttttaaggc catctgtcag atgataacaa gcaaagtcta cggaaagagc tgaaccagat
    27301 atctcagctc ccagagccaa atctttttta tagagctcat tacgataggc cgcaaattca
    27361 taaaggcgtt caacatcctt tgcatcaaag agcccatctt tattcggcgg aatattaagc
    27421 aggagtggag ttcctctccc aaccgagtga aagtagattt ctaccaattc ctcgagagac
    27481 ttaggatact gatcctcatg gtagaaccag cccggccgga tagagacatc tgcctcacca
    27541 attgaaaaaa tcgtacccga aggatctccg tgctgaagat agtccagctc tgcttctgtt
    27601 cctagtttgt caggattcac cttttgccat aggggatcac ctgcatagcc tcgttcatta
    27661 ccaatccagc gaatgctagt gccttctgtt gaaaaaatca agcaatcgcc ctgcaggtca
    27721 cgaatggttt caaaccatgt ctcaaattca taattgacct tttgcgcgcc ctctcctctg
    27781 gcaccatcca tccaaacctc agcaaatttc cctccatttc cataggcagg atttgataag
    27841 atttccttca gctgagccag ataataggca ttgtagtccg cttctcggtc cacatgatag
    27901 aggggactat gggcatccca cggtgacagg tagaccccca tatccatatc aaactctgtg
    27961 gcagcttgag atacttcaag aagcaagtcg ccctttcctc ttctccaagg actgacctta
    28021 atcgaataat ctgtgtgagc tgtcggataa aggacaaagc catcgtggtg cttgaccacc
    28081 aaaatcaact ttttgaagcc cgtttccttg agcacacgaa cccactcacg tgcgtctaac
    28141 tgtgtcgggt taaagcgttc aggatcctcc tgacctgttc cccattcctg attataaaaa
    28201 gtattaggtc caaaatggat aaaggctact agttcatcct ctaaatacgc taactggacc
    28261 tgactaggca aggggctatg cggttttatt tctcttacca tactacttcc tatctacatt
    28321 ttcttaactt tttggcatgt acttgcaatt ctgttaacgc tagtggattt accaagtttt
    28381 caaatcgaag acgaagggca taggtttcca ccttgtcaaa ttcaaaacga agctcttcat
    28441 ccttgtcacc tgacactttt cggatagttg ataccggtcg ccaattctcc tcttgtttga
    28501 gagcagaatc cttatccaaa tggtttggag tccgaggcaa agtaggctca ttccctatgt
    28561 aataatcaat aaagctaggc tccaccgcca cgtattcttg attctcaaca taatacaagg
    28621 tcaggttatc cacaaatcgc ggttttaaaa tccctacatt tccaaaaaga atacccacgc
    28681 tggcttgctc tgacttggta atccaagtat tggctgtcga tttcttccga gaaatgacct
    28741 tgtcattgag gtaagaggca gggtgattcg attctgagtg agaagcaaag accagaggta
    28801 ggttggagcc tgtccactga ttggaaataa cttccccatc tacactagca tctgtcacat
    28861 gaatggtgac tgttgctggt aacttacagc ccactacttg tcctgtgaac acacattctc
    28921 ctacctgagc atagacttgg ggttcgagtt catcctaagt taccttggcc gtatctcgtc
    28981 tgccatctga taagactagc ttaactcggt ctggtaaatg tggggcttcc ttgacaagcg
    29041 tccaaaccct ctcagactca atagcacaaa tcccttgaac acaaacctga gcagaagcct
    29101 ctaaatccag accctctagc tgaccagata ccgtaaactc atgaaatctt gccaaatctt
    29161 cttcaggaat ctcctcccag acaaccttga ctcgttttgc accgcctgac tcatagtcta
    29221 ccaagactga aaatggcaac tgtggataag ttcccttatc tgtatacaag cgaagtggtc
    29281 ttacaaaaac tgcctgccct agtgaggtat tttctgcaat ctgcaaatga gtttgatagg
    29341 tcttcccttg ataaatggca tgaatagcca agtcgcctgc agacaagcaa tgaagtactc
    29401 cctgcttgat aatggcgtgg gcactaccac tcgtctccca aaacacttca ctattcccta
    29461 ccttgttcac aggattatcc acagtttgtg gataaagtcc aatagctggg gaagctcctt
    29521 cttgcaaacc tgcctgatcg tccactcgaa tctccaacaa gcgctgattt ttcactggct
    29581 ggcaatcaaa agcctctccc actaagagat caaaacttgc tggctctagc cctctggcac
    29641 tagcttttac tcttacttga cctgcctgct ccaagctctg agcctgataa cgttcacgac
    29701 tggcctgcct gccgttgtcc acacccacaa tacgagctgg tccttcaatt ttgaaatgaa
    29761 gctgattgga agcactcggc acccaatttc catccttgtc caatacatca aaatagagat
    29821 agaggaggtc ttgcccatct ggctctagtt gtgttctctc ggcatgtaac ccaattttag
    29881 caggcttacc cgcagtcacc accctatctt ctgccacaat ctgaccttga cggtcatagg
    29941 ccacaacacg caattctccc ggttgataag ccaaacgcca ttcgagatag agttggtcag
    30001 aaccttctcc ctcttgatat tttctgccat ctgaagtcca tttctcttga aaagtcttcc
    30061 tgccttgaga ttttccattg agaaatagct ctactggacc agcatttgaa tacactcgaa
    30121 ccgggatatc cccatactta tccacagctt gttgataact cttgtggatt tcccaattcc
    30181 agtggggcag gatatgaacc acgggatgct gatctaggtc caaccactga ctttgataga
    30241 gataataatc atttttagga atcctcgccg tgtccacaat cccaaaataa gaactcttga
    30301 caggcgtgtc attttgattg tgccaagggg tcggctcacc gatatagtcc actcctgtcc
    30361 agataaactg acctgcgtag tctagcctat ttctatctgc tatcaaagaa gccgtcgctg
    30421 tcttccccca aggaactcga tcattgccat agtctgactg ttcaaaattc cgcacgcgac
    30481 gattatcccc aacctattcc ttatctgggc gaaaatagct atcacacgtt cgggtagccg
    30541 atgaggtttc agacccgtaa agtcgccact tgggatgtct tttgcgaatc ccgtcaatat
    30601 tatcttccga gtaattcaac cccaccacat ccagcaaatc agcaatcttt tcatgacctc
    30661 cagaaccatc tccaaagcga aattgatcca ttcccatggt cacaaaacgg ctatcatcaa
    30721 cctccttaac cctttctagc aagcgtttga cagttttcaa tgaatgaaca tcgctatttg
    30781 cttcgctgac ttcatttccc aaagaccaca taaaaatcgc tggattgttc ttgccacgct
    30841 caatcatagt gcgcaaatcg taatccgacc agaaatcgcc tgctttcgct tctggatgag
    30901 tcgcttcttc ctcaaaaaag cgaccatagt catattcttt cttgcctcca taccagatat
    30961 caaaggcttc ttcttggatg agtagaccca ttttggcaac cacatccagc aaaatactac
    31021 tggctggatt atgcgtgatt cgaatcgcat tgacgcccat ttccttcatc tggcgcaagc
    31081 gtctctcagc agctgacctg ttttccatag ttcccaacgc tccgtagtca tggcgcaaac
    31141 aaaccccatg aatcttcaac cagcgaccat ttagaaagaa gcccttatct gcttgccaat
    31201 ccatatagcg gtaaccaaaa ttctcctctt cttcatcagc taaaatgcca tttttgtaaa
    31261 ggcgagtctt caattggtaa aggtgagggg aatcaatatc ccaaagcaaa ggttggaaaa
    31321 ttgatatggc ttgttggaaa tgatgtttgt ccccagcttc aatcactaca gagtctgtcg
    31381 cctgccagtc tgaaacctgt tgtccatcat accagatact ctgttctaaa tacaccgaca
    31441 cagactgagg cccatcattt gaaaccttgc tttcaagctg ggtttccacc catccatctc
    31501 tttgttcctt tagcttggga ctttctatct taatcccata caaatccaga tgaactgcat
    31561 ctgtcatcaa caattttact tctcggtaaa taccgctacc agagtaccaa cgactgctag
    31621 gttgctgatt ttccacaaaa accgcaagct ggttggccgt cccatcattt cttagataag
    31681 gcgtgataac atatgaaaaa ggtatatagc cattgggata atagcccagc acttgcccgt
    31741 tgatatagac ttgggcattc atgtaaactc catcaaacaa caaacgcacc gatacaagac
    31801 tggcatcttc ttccaagtaa aactgcgtcc ggtaccaggc ctgaccccca tttagctgac
    31861 caccctcatt ttgcgctggc gaatactggt caaaatcatt gtaaatactc cagtcatgtg
    31921 gtacttgaat cgactgccaa ttttccctct gaaaatccgg cgccaaggcc tcttctttcc
    31981 ctacctcttg actaaaaaac cagtgatttc gtaaaacttc ttctcttctc atacaagcat
    32041 tcctctttaa acgactcgat ttacttgact atagcacaaa acaaaagcgc tttcaagatt
    32101 tcctctatca ctccctaaat actcagaaaa gattctataa tttgtggaaa agtctgaaaa
    32161 tcactccata ttcaagcaaa ctatcatttt caagaaataa ggtcaaacct tacaagagag
    32221 caaaaaacac ctctctgaat gttcattcca gagagatgtt ccttttgtct taactattgt
    32281 aaatcgactg tctaaagtca tctgaatctt tgagataagc tttataaatc gcttttttca
    32341 gtttttgaac tggagtttcg ataaactcaa acttttgagc cgtggtattg cctgctttta
    32401 tctgggctag ttcagctaaa acagctttct gcatcaattc ttttaacttc tgacttgtca
    32461 gacttatttg ctgaccttca tattggattg tcaaaggttt caattgattg agcctatcta
    32521 ctctttcctt gaactgtgct tttttaaact cagcatagct cttaccattc aaaattttat
    32581 tgaaaatgta agtatcagat agaggcttgt tctcagactc tgctacttgc ttgtattgat
    32641 ttgatacata aggtacaaat ccttcataat agcccaaagc agccatcaat tcaaatgctt
    32701 gttttctaaa ggtgatgtcc ccactcatac cagagtcatt ttgactaaca ccataaatgg
    32761 tatcaaacat atccactaaa taatatccat tagcttttac atcacctgtt gcataaaatc
    32821 catttatgat ataacgatta actaaaatat tattatcaat caagctattg atatccgtta
    32881 gtttttccgc ttctgccaat gtgatttccg agattttttc actcttgtgc gtagctttaa
    32941 ccgctgaatt tgtatatgtt actgtcgctc taggtccctt cgacgcaatc ggtgttattt
    33001 ttttgaaata tttagtttta tcttcagctg taagttgttt tgttgcttcc gcttctaaat
    33061 aatctaaact atataacaca tcaaaacttc catgcatata agatttcaag tctgcatctg
    33121 ttttgaatct atctggtgtt ttgttgtaga agccattttt cttactttca tcgtaaacga
    33181 agtttaagtt aaaatatgta tctttttctg gtgtgtaaga attttcaaag atacctcgag
    33241 cataaaactc cgcagctgta ccatctcgac gaccatgatt attaaacagc actgttctgt
    33301 ctaataaatg cgtcatttcg tgagagtaag tcgctgagcc tctatcatcc agaactctat
    33361 ctatgaagta acggacacct actccattgg cttctgcacc tacattttgc gatggtgaat
    33421 acaggcctag aggtgtcata aagtctttaa cccctttatc tgctgttggt cctgattctt
    33481 tagaccatgt tgtccctatt ccagcagacg tatccgccgt gtattttttc atcgtgtcta
    33541 caatcactct atttgtaact aatttagaac gattttcttc ttttgtaatt ctgtataaag
    33601 tatcaacgta tgcagcctgt cttgtcgcag tcaattctat caatgcttta actttttcta
    33661 attcttcttt atacttaact ggatttgttt tctctaaaga agtatccata tacgttccga
    33721 tatttccgta ggtcaccgtc gctatgttag ttatagcata cacgcttggt tctttaatat
    33781 ttaccaaacc taataatata gctacatttt gttgtcttct actttcaatt tgaagatttt
    33841 cagctccata tttctcagga ggtgtagtta attttgtata taattctact ttttcgtcag
    33901 gtttctgttt cgaaggcttt tcaactacaa tagctttagt cgctttcttc aaccacgtat
    33961 cgccatccat attagtgaat gtagttctgt tgtaatctag gaactctaat aatgttggtt
    34021 tatctgtaat tttaccaaag tatttctcaa atgtttttgg actattggtt aatcttaatt
    34081 catcataact catagaccca aggtatgtta accaatctaa agaagtaagg tcttttttac
    34141 cgaacgagct tggattataa gctagaatat cacggatatt ggtatctcca aaatcaatat
    34201 tataaaaacg attgatatag gataacccta gtaatatttt ctctttatta gcttcaatat
    34261 caccttttac tttttctcta ttttgttgat tgtcacctaa aatactcaag gtatgcgccg
    34321 caactttttt caaactagct tctaaatcgg ttttagtcgc atcgagtgtt tctttaatag
    34381 ataatttttc aagatattct tttcgtagaa tttcttttac ttcttcatca gttatcgccg
    34441 gattagtttt tcgtaattct tttcgtttta agaataaatc tcgatttatt tctatatctg
    34501 atggagctaa ctgcgctttt aacttctcat ttgtcaacaa gtctacattt ctcatctccg
    34561 cagtagcttc cgttacgttt actgcatttt ctaattcgct attaattggg agtaaatgag
    34621 gtttgtcttc tttagtgcca accaagatta ctttttggcg catagcttta gttgtttcag
    34681 tcttctctac tggatttgtt aactctcctg tctccggatt aacttcataa gttttagtga
    34741 cggttgtttc cccttgttca cctgcatcct caacctcttc ttttcctttc ggaagttcag
    34801 ggttatcttt tctcaactca gtgatttcta taggtgacac tatcttttcc acatttccaa
    34861 cttttactat tttgtcttta gctggaatat tttctattgt agtttcttct gagatagctc
    34921 ctgtttcttg atttactgtg tattttgtag ttgatactgt acgccctttt tcacctggtg
    34981 tttcttcttg ttgcacattg taacttaaat ctggcgatgc tttataaact gtcttaaaag
    35041 gaatttcttg tgattgaact gttggttttg ttcctactgc cgttattttc gcttgcattt
    35101 ctttggctac ttttgttgaa acttctggct ccgtcaagtc tcctgtttgt gcatttactt
    35161 tataaacacg aatagtagtc gtttcttcgt cctgaccttg atttctgact tctttgacac
    35221 ctttatcaag tgactcatcc gcgacaaact gttcacctct tttggttgtt gaggttgttt
    35281 cttctacatt tccaacctta acaactctat ctactggatg tttttctatc tttgttgaag
    35341 tgttttctac tattttccca gtactttcat caaaactgta agaagtagtt gtcacttcct
    35401 taccattttc gcctgctact tctacttgtt gctctttgta atttaaagct ggcgatgctg
    35461 tatagactgt tttatagtcc aatacttttt ctttcgttac tggactcggg acagttggtt
    35521 gcacttgtga atctgactgc tcttggggag ctgagggttc aggctgaaca gctggagctg
    35581 gttcgtttcc ttgacttggg ttgacctctg gagatggagc cgtttgttct ggttgttttt
    35641 ggggttcttg tggggcagat tcaccagcat cttttgcccc ctcaactgga ttctccagct
    35701 ggttctcctc acccttttgt tccgcaggag attgatcttc ctctcgtcct gatcccacgg
    35761 ctgggcttgc tagctctggt tgcttcggct cggcttcggg tttgtcaggt gtttgtttct
    35821 cgcccggcgt ttcttctgct cctggtcttg gttgtcctat tccagcagct ggttttgtct
    35881 ctgtttcatt ctctactatt ggttttttct caattttttc aggttgaact ggtttaactt
    35941 cctctggctc tggagttaca ggttgtgttg gttttggtgc aacttcttcc ttagtcccaa
    36001 ctgcaatcac cttgttctcc ggctcttttg tgactatatt ttctataact ttgctagatt
    36061 tttccccgtt aacgatagtg acttccgtat agatggtgcg ttcaccaaca acaccttctt
    36121 gaacaacttt agtttgccct ttagctaagc ttgcatcttc ttgttctatc gtttggaaag
    36181 caatctcctc tgtagtaact agcaattctg gtttctctac tgtggcattt aacacgcctt
    36241 cctcaggact tggtttataa tcactattat tctctgcttt cggttgttct actttgggat
    36301 ttcctgcaat ttcttcctta gtccctatag gcacaatttc atcaggagct tgtttgctta
    36361 caggagcttc aacaattttc tcaactgcgt aggatggttg aggagattgc acaaaatctt
    36421 cagtcgagct aaaatgagat gcagtctgtg gtacaatctt cttagattga ggttctgaac
    36481 cgtcctcctt tttagataat gctggcgact ctaccttatc aacagaaagt tccttgttac
    36541 tactgtctct taccaaataa tatcccgtaa attcatatcc ttggactctt tcaggacttg
    36601 gtagaaactg accttctacc cttttaacaa gggccggttg caattctacc agattttcga
    36661 aagcagagat ggatgctccc catccaccaa cagcaaagac tgtcacaagg aagtaagacg
    36721 ctcccctttt tctcttgatt aaagtgaagg aaagcaataa taatcctgct cccaggataa
    36781 acgtcccatc attagaaaaa agacctgttt ctggtaatct tgtagccaat tttcgataga
    36841 caaagtagta ttcttttccc tcttttacct caatcttatt ttcttcaaac cattgcaact
    36901 cagatttcag cttttcagat aaatcctgct catccaaata atgacttgaa attagtgttg
    36961 aactcgtttc ggtagcctgt acaggctgag catccatacc agcaaaaaat aaactcgttc
    37021 ctagcaagac cgaacaagct cctattgcat atttcctcaa agaaaaacgc tgctttcgct
    37081 caaattgaaa ttctttcatc ccatctccca tcattcatta ttactgtata tttagtatat
    37141 cagaaatagt ttgtattcac aaatctttct agttattccc ttatcattcc aagttaaggg
    37201 caacaacata caataatttt tatttaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    37261 ttccatctgc aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct
    37321 ctttgatttt cattgagtat aaatgtatat caatgttctt tgtttttctt aacaaacgca
    37381 acgcaaaaag agcctgttgc caagctcttt agtctattat ttcttctcag cgcggagggc
    37441 tgacaagatt tgtgtacgga tatcatccac accatttggc gtatttggta aaaagatcgt
    37501 ttgatttcct ttagaagcaa aggtattcaa ggtatccaag tactggttgg tcaagagaat
    37561 ggacatgatt tgttcttctg tcataccaac attggcttcc ttgagttcgg tgatagactc
    37621 tgccaatcca tccacaatcg ccttacgttg ttgggcaatc cccacaccat gaagacgatc
    37681 tttttctgct tcggcttcag ctgcagtgac gattttaatc ttgtcggctt ctgccaattc
    37741 ttgcgctgca acccgcttac gttgcgctgc attgatttca ttcatggatt gcttaacttc
    37801 tgcatctggt tcgaccttgg taatcaaggt tttcacgata atgtagccat aagttgtcat
    37861 ttcttctgct acttggtgtt gaacttcaag ggcaatctca tcttttttct caaacaattc
    37921 atccaaagtt aatttgggaa cagaagagcg aagggcgtct tcaatataag atttaatctg
    37981 agattctgga cgcatgagtt tatagtaggc atctgtcacg ctctgctcat tgacacggta
    38041 ctgagtcgct acattcatca taacgaacac attgtccttg gtcttagtct caaccacaat
    38101 atcgctttgc aacaaacgca actgaatccg cgctgcaatc gagtcgatcc caaaaggcaa
    38161 gcgaatatga ataccgctat tggcaacctt ttggtatttc ccaaagcgtt caataatcgc
    38221 caccgactgc tgacgaacca cataaactgt gctcagtgtg actatcagca ataggaacac
    38281 acaaacaatc agaaaaatca tgaaaaatat tgccataatg gaacctccac aagtattttt
    38341 ctagtattat agcacattta aagaagactg tgcagttttt actgcgattt ttcctgaaat
    38401 gtcaataatt agaggtgaag ccaaatttca agttactaat ctcttttttt cactgcatta
    38461 acttctatag aatcttcatc catagtcaga gaatgacttg ccttaatttt tctctcgtgc
    38521 tatactattt atgaaattaa tgaataggag atatttcatg aaatcagcaa aaactactgt
    38581 tacaatcctt tctgcacttg catctgtcgt cttattatct agttgtgcaa caaagtctac
    38641 agaaacacag acaagcaata agagctcatc tgataatcag attacaatga catatgacca
    38701 actacggtca agagaaaata ctatgtcaac cctttggtat taaaaatcag ctgaaaccaa
    38761 agccttgtat ctacaaggtt ataatgttgc cacagatcgt ctaaaggaat tactgaaaac
    38821 agaatcagac aagccttatt caatcgtttt gaacttagat gaaacagtct tagataatag
    38881 tccttatcaa gttcaaaata tcaaagacgg aacagcattc acacctgaaa attgggatat
    38941 ttgggttcaa aaagctgcag caaaagccgt cccaggagct aaggagtttc ttcaatttgc
    39001 caatcaaaac ggcatccaaa tttactatat ttctgaccgc tcagttaatc aaatagatgc
    39061 tacgattaaa aatctagaaa acgaaggaat ccctgtacaa gggcgtgatc acctcatgct
    39121 cttagaaagt ggtgtaaaat ccaaagaagg gcgtcgccaa gcagttcaag agaaaactaa
    39181 tctagtatta ctatttggtg ataacctcgt agactttgca gatttttcga agacttctga
    39241 atctgaccgt gataaacaac ttgaagaatt gcaaaaagaa ttcggtgaaa aattcatcat
    39301 cttcccaaat tcaatgtacg gatcatggga aacaactgtc tacgctggca ataaattgga
    39361 tgctaaaggt caagtggaag aacgccaaaa ggctttgcaa ggttttaata aataaaacaa
    39421 ataagctgat tctatataaa ctaaggctaa cttacaatct tcaaaaagtg gataggaagg
    39481 aattctgata atcagaaaac tttcctatcc actttttgaa ttgatataac atcaagcttt
    39541 tatacatctg atactatatg ttttttgatt ttaaagactt tttgcctatc ccctatattt
    39601 caagaattaa gcaatcttga tgatctaaat ttgttgtgat ataatatttt tgtcatcggt
    39661 taccgattac gttcctatgg gttcgtgaga ggaggtgaaa ctaatga
//
LOCUS       DAVFJR010000017        38275 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVFJR010000017 DAVFJR010000000
VERSION     DAVFJR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.018"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..186
                     /locus_tag="VU722_001081"
     CDS             <1..186
                     /locus_tag="VU722_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEU1772072.1"
                     /translation="MMESFFGILKSEMFYGYEKSFRSLENLEQAIVDYIDYYNNKRIK
                     VKLKGLSPVQYRTKSFE"
     gene            complement(530..682)
                     /gene="cibB"
                     /locus_tag="VU722_001082"
     CDS             complement(530..682)
                     /gene="cibB"
                     /locus_tag="VU722_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU1772073.1"
                     /translation="MMKDLNNYCEISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(684..869)
                     /gene="cibA"
                     /locus_tag="VU722_001083"
     CDS             complement(684..869)
                     /gene="cibA"
                     /locus_tag="VU722_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU1772074.1"
                     /translation="MINFDVLDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            1047..1730
                     /gene="tsaB"
                     /locus_tag="VU722_001084"
     CDS             1047..1730
                     /gene="tsaB"
                     /locus_tag="VU722_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU1772075.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            1727..2164
                     /gene="rimI"
                     /locus_tag="VU722_001085"
     CDS             1727..2164
                     /gene="rimI"
                     /locus_tag="VU722_001085"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU1772076.1"
                     /translation="MIEIKRIQQQPALAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            2154..3164
                     /gene="tsaD"
                     /locus_tag="VU722_001086"
     CDS             2154..3164
                     /gene="tsaD"
                     /locus_tag="VU722_001086"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU1772077.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAEITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDMYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNSEQKGESLSAEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLATEITDVNVMIPPLRLCGDNAGMIAYASVSEWNKENFASLDLNAKPSLTFDT
                     IE"
     gene            3268..4131
                     /locus_tag="VU722_001087"
     CDS             3268..4131
                     /locus_tag="VU722_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU1772078.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            4300..4526
                     /locus_tag="VU722_001088"
                     /pseudo
     CDS             4300..4526
                     /locus_tag="VU722_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4611..6996
                     /locus_tag="VU722_001089"
                     /pseudo
     CDS             4611..6996
                     /locus_tag="VU722_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            6996..8222
                     /locus_tag="VU722_001090"
     CDS             6996..8222
                     /locus_tag="VU722_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1772079.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFPLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            8666..9323
                     /locus_tag="VU722_001091"
                     /pseudo
     CDS             8666..9323
                     /locus_tag="VU722_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
     gene            9313..9636
                     /locus_tag="VU722_001092"
     CDS             9313..9636
                     /locus_tag="VU722_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU1772080.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPCILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLAF"
     gene            9740..10570
                     /locus_tag="VU722_001093"
     CDS             9740..10570
                     /locus_tag="VU722_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772081.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            10724..11578
                     /locus_tag="VU722_001094"
     CDS             10724..11578
                     /locus_tag="VU722_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU1772082.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKSLFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            11678..13051
                     /locus_tag="VU722_001095"
     CDS             11678..13051
                     /locus_tag="VU722_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU1772083.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            13044..14105
                     /locus_tag="VU722_001096"
     CDS             13044..14105
                     /locus_tag="VU722_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU1772084.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            14107..14799
                     /locus_tag="VU722_001097"
     CDS             14107..14799
                     /locus_tag="VU722_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772085.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(14829..15398)
                     /locus_tag="VU722_001098"
     CDS             complement(14829..15398)
                     /locus_tag="VU722_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU1772086.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            15533..16147
                     /locus_tag="VU722_001099"
     CDS             15533..16147
                     /locus_tag="VU722_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU1772087.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLETVYEIIHEKLATK"
     gene            16197..17781
                     /locus_tag="VU722_001100"
                     /pseudo
     CDS             16197..17781
                     /locus_tag="VU722_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843414.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            17793..19079
                     /locus_tag="VU722_001101"
     CDS             17793..19079
                     /locus_tag="VU722_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772088.1"
                     /translation="MYKVLIVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEDLEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDGAGFVSYLGDKENWWIGLSKEK
                     QGSFTTPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKALFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTVHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSIKDISKDLFINPVYLGQSIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNIGYFYKVFRKLCGKLPKAYRKQVETIL"
     gene            19140..19673
                     /locus_tag="VU722_001102"
     CDS             19140..19673
                     /locus_tag="VU722_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772089.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVVEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYSYVGLQDAVQLVQDESMRLTMSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            19751..20221
                     /gene="nrdI"
                     /locus_tag="VU722_001103"
     CDS             19751..20221
                     /gene="nrdI"
                     /locus_tag="VU722_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU1772090.1"
                     /translation="MKTISLVYISLSGNIESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKRVAAIIADLYELEKEN"
     gene            complement(20514..21776)
                     /locus_tag="VU722_001104"
     CDS             complement(20514..21776)
                     /locus_tag="VU722_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU1772091.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNKEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSCL
                     KHLAIVGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(22087..22545)
                     /locus_tag="VU722_001105"
     CDS             complement(22087..22545)
                     /locus_tag="VU722_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU1772092.1"
                     /translation="MKKQVFHDAAADVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNLGNHLFSRDWSMLRATLTHFFLMMAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(22542..22982)
                     /locus_tag="VU722_001106"
     CDS             complement(22542..22982)
                     /locus_tag="VU722_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772093.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQRETIK
                     GKIDDQVYLVKIGKIQCFYIENRKVLAETASQTYSIDLRLYQVLECLPTSFIQISQSE
                     IININSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            23188..25137
                     /gene="mutL"
                     /locus_tag="VU722_001107"
     CDS             23188..25137
                     /gene="mutL"
                     /locus_tag="VU722_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU1772094.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(25462..25929)
                     /locus_tag="VU722_001108"
     CDS             complement(25462..25929)
                     /locus_tag="VU722_001108"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU1772095.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(25930..27135)
                     /locus_tag="VU722_001109"
     CDS             complement(25930..27135)
                     /locus_tag="VU722_001109"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU1772096.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMIENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIEKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQILKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANAYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(27155..27790)
                     /gene="ribE"
                     /locus_tag="VU722_001110"
     CDS             complement(27155..27790)
                     /gene="ribE"
                     /locus_tag="VU722_001110"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU1772097.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTWEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(27775..28875)
                     /gene="ribD"
                     /locus_tag="VU722_001111"
     CDS             complement(27775..28875)
                     /gene="ribD"
                     /locus_tag="VU722_001111"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU1772098.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCKILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPIGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(29008..29122)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29279..29872
                     /gene="ruvA"
                     /locus_tag="VU722_001112"
     CDS             29279..29872
                     /gene="ruvA"
                     /locus_tag="VU722_001112"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU1772099.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            29882..30445
                     /locus_tag="VU722_001113"
     CDS             29882..30445
                     /locus_tag="VU722_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU1772100.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            30442..31119
                     /locus_tag="VU722_001114"
     CDS             30442..31119
                     /locus_tag="VU722_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772101.1"
                     /translation="MMSNKNKGILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(31256..32287)
                     /locus_tag="VU722_001115"
     CDS             complement(31256..32287)
                     /locus_tag="VU722_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU1772102.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLRLNPIFLPHS
                     LKGLDFIKDHPEARAENLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(32542..33225)
                     /locus_tag="VU722_001116"
     CDS             complement(32542..33225)
                     /locus_tag="VU722_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU1772103.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(33237..34181)
                     /locus_tag="VU722_001117"
     CDS             complement(33237..34181)
                     /locus_tag="VU722_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU1772104.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            34313..37144
                     /gene="uvrA"
                     /locus_tag="VU722_001118"
     CDS             34313..37144
                     /gene="uvrA"
                     /locus_tag="VU722_001118"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU1772105.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVDMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGDQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINNILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            37137..38198
                     /locus_tag="VU722_001119"
     CDS             37137..38198
                     /locus_tag="VU722_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU1772106.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIVGIVKDMGLTRIGFEDEISVSYY
                     HRMQATFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACFISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMTLTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT        11245 a         7173 c         8275 g        11582 t
ORIGIN      
        1 atgatggaat ctttctttgg cattttgaaa tcggagatgt tttatggtta tgagaagagc
       61 tttagatctt tagaaaacct tgaacaagct attgtggact acattgatta ctacaacaac
      121 aagagaatta aggtaaaact aaaaggactt agtcctgtgc agtacagaac taaatccttt
      181 gaataaatta tttgtctaac tttttggggg cagtacatat gctggggctt tttgtttgag
      241 gatatagaga tagtagattt acgacacgaa aattccaccc catctatcaa gatgaggtga
      301 tctttgcatt tttctaaaat gacatgacaa tggaattttc agagcttatt atttttatgg
      361 gagtcattgt tctgctcaaa aatagagttg aagcataaaa ataaaacaat acaaacagat
      421 agatcaattg gtaaagggat agtagtcatg tttaaatcat tgagaatgct gagcaaactg
      481 taagagatga agacaataaa atttatcctt ctaaaaatgt gtttcttatc tagcatgact
      541 taccaaactt tttacgaagg tcttttccaa tggtataacc tgccataaat aaagcgatac
      601 caacacctac accaaagcca ccctttattt cttgcaattc cttattagaa atttcacaat
      661 agttgttcaa atctttcatc atattaatct cctcctaaaa aataaccagc tgccaaacca
      721 gaacctataa gtgctgttcc acctgcaata gctttccaag atactgctac tccaaagata
      781 accaagggag cgagaccgcc atcaatatct gataattcat tttcagataa ggataaaaat
      841 tgattgtcaa gaacgtcaaa atttatcatt gaactttcct ccttttttct tgttcacttt
      901 tatattcgta aaagaaaagg aaaagtgagc atttttttaa attattttta gttaagtgag
      961 ggcactcttg tctgggggca aagaaaattc ccatgtgcca gcttttgtag tataatagta
     1021 agcagataaa aagataggaa tgtgttatga aagtattagc ttttgatacg tccagcaagg
     1081 ctctttctct ggctatttta gaggacaagc aggttcttgc cgagacgacg attaatatca
     1141 agaaaaatca cagcattacc cttatgcctg ccatcgattt tttgatggca agtttggatt
     1201 ggacacccaa ggatttagac cgaatcgtgg tggcggaagg accaggtagc tatacaggct
     1261 tgcgaattgc ggtagcaact gccaaaactc tggcttatac tctgaatatc gagttggttg
     1321 gtatgtcgag tctcttggct ctggtgcctt accaacaaga aggtttgttt gtccccttga
     1381 tggatgcgcg tcgcaataat gtttatgcag gattttatga aaatgccaaa cctgtcatgg
     1441 cagaagcaca tctgcctttt gagagagtca ttgagctaat caagggcgct agtcaggtaa
     1501 cctttgtcgg agaagttggc ccctttgttg agcagattca aaaacacttg ccaaggactg
     1561 attacaaaga aacattgccc aatgcagcta atctagctct tttggcctgg gacaaggaag
     1621 cagactcctt gcatgatttt gtgccaaatt acctcaaacg tgttgaggca gaggaaaact
     1681 ggctcaagaa ccataccgag tctggtgagt cctacattaa acgcctatga tagaaatcaa
     1741 acgaatccaa cagcaacctg ccttggctca agctatctac gctgtcatgg cagctgttta
     1801 cccagtcagt ccttggacac tagaacaaat ccaagcagat ctgtcccaag accagacttg
     1861 gtatgctcta gcttatgatg gggcagaagt gattggcttt ctaactgttc aggagactct
     1921 ctttgaagca gaagtcctgc aaatcgctgt caaaggagcc tgtcagggtc agggaattgc
     1981 gtcagcttta tttgctcaat tgccgacaga taaggagatt ttcctcgaag tcagaaagtc
     2041 aaatcaacga gcgcaagcat tttacaagaa agaaaagatg gcggtcatcg cggagcgaaa
     2101 agcctactac catgacccag tcgaggacgc cattatcatg aagagagaaa tagatgaagg
     2161 atagatatat tttagcattt gagacatcct gtgatgaaac cagtgtcgcc gtcttgaaaa
     2221 acgacgatga gctcttgtcc aatgtcattg ctagtcaaat tgagagtcac aaacgttttg
     2281 ggggcgtagt gccagaagta gccagtcgtc accatgtaga ggtcattaca gcctgtatcg
     2341 aggaggcgct agcagaagca gagattacag aagaggacgt gacagctgtg gcggttacct
     2401 atggaccggg cttggtcgga gccttactag ttggcttgtc agctgccaag gcctttgctt
     2461 gggctcatgg acttccgctg attcctgtga accacatggc gggtcatctc atggcagctc
     2521 agagcgtgga gcctttggag tttcccttgc tagccctatt ggtcagcggt ggacacacgg
     2581 agttggttta tgtttctgag gctggtgatt acaagattgt tggagagacc cgagatgatg
     2641 cggttgggga ggcctatgat aaggttggcc gcgttatggg cttgacctat ccagccggtc
     2701 gcgagattga cgagctagct catcaggggc aggatatgta tgacttccct cgtgctatga
     2761 tcaaggaaga caatctggag ttttcattct caggtttgaa gtctgccttt atcaatcttc
     2821 accacaattc cgagcaaaag ggagaaagtc tgtctgcaga ggacttgtgt gcttccttcc
     2881 aagcagctgt cttggatatt cttatggcaa aaactaagaa ggctttagag aaataccctg
     2941 ttaaaaccct tgtcgtggca ggtggcgtgg cagctaataa aggtctcaga gaacgcctag
     3001 caactgaaat cacagatgtc aatgttatga ttccacctct gcgtctctgc ggagacaatg
     3061 caggtatgat tgcctatgct agcgtcagcg agtggaacaa agaaaacttt gcaagtttgg
     3121 atctcaatgc caaaccaagc ctcacttttg ataccataga ataaagagtc agcttagggc
     3181 tggctgtttt atttttctaa ctatcagaat attttgacaa atgaacacaa ataatgatat
     3241 aatatgcaaa agctaggagg tggtaggatg attgaaaaaa tggaattggg agaattttac
     3301 aaggaactgc gcctggcgag aaagctcaag cagtcagatg tggcttgtga cgggctaaca
     3361 gcttctcagt tgtccaagtt tgagctaggg cagtccatgt tgtctgctga taagctcata
     3421 ttagccattc aagggatcaa tatgaatttt gatgagtttg ggcacaagct caacaactat
     3481 caagaatctc cacatatgcg aatcggtcga aaggttgtgg atcgctttgc ccatcaggat
     3541 atagctgctt tagagcagct attggaggaa gtcgatcaag aacagatggc gcagacctat
     3601 cgtcgtttga atgccattgt gattaaaaat gcactccatt ccttagataa aagctacccg
     3661 ctaacagagg aggatagcga gtttttgact acctacctct acgctattga gtcttggacc
     3721 tggtttgaac tctatctttt ttgcaatact atgcccttct tgagcaatca agatctgatc
     3781 tttttatcaa cctccttact cgaaaaatcc aaggaattta aagagttagt acacaatcga
     3841 tggtatatga aaagtggtta tcttaatatc atctcagaac ttatggagcg caagctattt
     3901 tcttatattc caatctttga agctgagctg gagcgcatgc tccgtccata cgatgttttt
     3961 gaaaaagtat tgtggcagtt tttaaagaaa atgcagattt ttcttcaaac caaaggaagc
     4021 aatcaaaaag agattgaaca ctttatccaa tctctgcaag tattagaaaa tccacaattg
     4081 acagcccttt ttgaattgcg tttgcagcaa tacaaagagc ttatcgatta gttagaaatg
     4141 ggaaaaagat aataatatca gcaacgatcg tcaataatgt taaaacttgt ttcttcatat
     4201 tacttccctc ctcattagta ataactttat tataccaggg aaataatcaa atctaccaaa
     4261 atcgcaaatc tgaaatttct ataagaaaaa atatcaaata tgcgattttc taaaataagc
     4321 caattttcgt gttataattt tcgtgttata ctgtacttgt aaagcacttg aagcaaatcc
     4381 taggtcgcag aagtggttta caaaaaaata atcaaaggag aaaagaaatg cataatctaa
     4441 tggaacttga attgttacct gaagagccag taattactgt atcacgggaa gtttgtaagt
     4501 ggacttgctc atttactgct ctttaagaat aactggttaa aattaaggat agttgattac
     4561 taattaacta tccttaattt catttcagag ataatgtatt tattatattt atggatagat
     4621 tacaaacaat gctgaataaa atacaagttg atacttacca taaaaatgga tggttatttg
     4681 tgaagtatag taacaataaa cttacacagg gatggaaact tcatgtaagc agtcaactaa
     4741 aagacgcttg taatattttt tatattgttg cacaagagct ggaaaaggaa agatgtaact
     4801 acaaagttct agattgtttg gatgagttaa aaaaattaaa ttctcctagg gaagtttctc
     4861 ctactgcaaa taagtttatc actatatatc cgtctagtag gaagcaggcc aaacgaataa
     4921 tattaaatct aaaagaaaag ttagaaaaat ataaagctcc aaggatttta tcagattttc
     4981 aatgtggtga gtattctcca atacattata gatatggtgc gtttaaagca attaaaaatt
     5041 acaatttttc tgaaaataaa attgtctaca tgatgaaaaa tagtagagga gaattagtag
     5101 aagatctgag attaagttat ccatatttgc cagaaggggt taaggattta tttactgata
     5161 tggaaaaaaa taaattattt aaaccctccc cggaaatccc agagaatcac cctttaaatc
     5221 actataatat cgagtgtatt ctaaaaaaat ccaatagagg aaatgtttac agagctatag
     5281 aaaaaagtag taatcagaaa gtgataataa gacacgcacg gccatatgtt tatagttgga
     5341 atgatggttt ctctgcaatt gatgaattaa agagtgaagc agcaaattta aaagtatttc
     5401 aggataagtc ctatacaaca gatttaattg aagagtttta tgtcaatgaa gattacttcg
     5461 tagtacagaa gtttatacca ggatataatt tttttgattt aaaaaatatt gatatcgaaa
     5521 aaaatgtaat cattaataat ataattgata ttattaatga tattcatgct gagggatatt
     5581 tagcagtgga tatttctcca acaaacttta tattggatga ttttggtcgt gttaggttaa
     5641 tagacttaga aaattttaca aacaaaaaca atactgttag aagggctgct acaaaattca
     5701 tgataaatac tgattgtccc tcaaaaatct gtaccattca acaggattat tttgcacttg
     5761 caatgttgag ttttgctatt atgcgcgagc atgttttaat atttgaagga gaggacgtct
     5821 tattaaatat aactgcttta gataaaatca agttttgtat gtatattgag aaagaaattg
     5881 ggaacataac taaatcgcaa tttaattggt tgatgtattt attgaattta agtgaacaag
     5941 agaagttaga ccgattcgag aagatgaagt atataaacga ttttgaagat aaaaatatag
     6001 aatttcattt aaagaaagtt gattcctcat tcaatcttca aattgaaaat gaaacgctta
     6061 ttaactatct tctttcgtta aatatgaata gagaaagcag gatactaaat tcaaatgaat
     6121 ttggagaatt tgttagtcca atatcgtttc aacatggctt atcaggatat ttgttttatt
     6181 tatcacatat gagagacatt tctgagaatg gtagaattat cgagtggatt atctctgaag
     6241 gaaatcaaaa taaaggaaat gtgtatctaa atggttgttc aattttattt ggttcttccg
     6301 gatatctttg ggtattatta gagttctata aaaaaattac cagcaacaat ccaagtagag
     6361 aattgatcat agataaaatt agagatattt ataaagactt gataagtagt tatcaaaaag
     6421 ttgaagtatt tgactttgct ttaggaaagt caggtatttt attgagtctt atgaaatact
     6481 gtataaattt caatgatgtc gatagtatgg aatttattag agaaaaaata gaggagttat
     6541 atttatattt tgtagatgag atacgaaatg ttaatagttt aaaagaatgt aattttgcac
     6601 atggtctagc tggaattgca tacgtaattt taatttataa ttcggaattt gaattcaagg
     6661 tagcttacga aaatagtatt aaggtattca ataatctgtt agaaaatttg ttagaaaatg
     6721 aatatagtag actaaatgca actcctacaa atttagaact atcgtggtgc gaaggaactt
     6781 caggaatctt actttatttt gagttattat atgacaatac gtgagaatgt gattgagatt
     6841 ttattaagta gatccaaaag agataaaaat ggtattttgg tatttgaatg tgaagaaagt
     6901 tcagatacat tatttgattt tggtatcgga aatctaggga tttattggtc tatccttggg
     6961 gaaagattcc catttgaact taagaaggag ttgtgatgaa agtatttctt caaaatagag
     7021 attttaggca attaactatc aaccagtgga tttcaacgct tggggatacg attttttatc
     7081 tggccttcct gaattatgtg gcagatgcat cttttgcccc tttggcgatt ttactcatca
     7141 cgatttcaga aaccctgccc caagttctac aaatctttct gggagttttg gcggattttc
     7201 aacatcatcg tgtcttgaaa tacacagtca ttagttttgc aaaatttttg ctttactcta
     7261 tagtgtcttt atcactttca gggcagtcct ttcccttgtt attagtagca tttatttgtc
     7321 tgattaacct cttgtctgac acgttgagtt atttttcagg cgccatgctc actccgattt
     7381 tcattagaat tattgggcaa gaccatctgg cagaagctat tggatttaaa cagtcaactg
     7441 ttagtttagt gaaaacaatc agtaatattc taggaggagt cttattaggt attctatcca
     7501 tccagtttat ttccttgctg aacgctctta cctttttaat cgcattttta ggtatcctct
     7561 tcataaaaac tgatctcttg aaagtagaaa aaacgattaa ctatcaagaa ggactctctg
     7621 taaaatcctt ttgccagcat ttgctccaat catcgaaatt gatatggaat atgaataagg
     7681 tgctcttggt tttgtttatt atctctacta gtcaagcagt gataaatgtt acagttcctg
     7741 tctctactct atttttgagg aatcaaccct ttttgaattt acaaacaggt caatctcttg
     7801 ccttgctatc cacttttgaa ctgtcagccc tgattgtcgg aagccttgta agtggctatc
     7861 tgcaacatac catttccata aaaacagctc tctatgcctc acttgtcacc cagttgcttc
     7921 ttctagtagg atttgccaca gttcgttttg actggattct catctttagt accttggatg
     7981 cctttttcgc aggtgttctc tctcctagat tgcaagaact cgtttttaaa caaatacctg
     8041 aggagtcaat gggagcagtt caatcctcta tcggtgccat tacggttgtt ttacctagct
     8101 tatttacaat agctttggta accattgcta ctagctttgg aactctggca gttagctttg
     8161 ttttattgct atttcttcta gttgcctttg ttatgcttct gaatattcgt gaaagtattt
     8221 agtggagaat ttctataata tatgtttgag actggattgc cagccttttt atgatggtca
     8281 aaatcaacag acttttttct cttttctgaa tgtgttataa tagactgaat ctgaaatagt
     8341 acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgttct
     8401 catcttattt caatctgcta tataatagtc catgctgtgg ctggattctt ttcagcctac
     8461 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta ggtatggtta
     8521 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac tacgtcagtt
     8581 ctatctgctt ttcattgagt attattaaga caatatgagg agaaagatga aagaaaaagg
     8641 attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca gtatcggcct
     8701 ggcctgtgga attatcggtg cgccctatgt gacacctgtt gagatgggct tgatgagtct
     8761 ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgcgg ttcaagctcc
     8821 tgtggcagct attgctatga cggtttttct aatcaatttg cgtctctttt tgttgagttt
     8881 acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta tgtctagtat
     8941 cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag acaaggtaaa
     9001 tccgatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg tggggacagt
     9061 agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttggct tggattttgc
     9121 ccctggttgg gatgtttatt ggtatttttg cttcgcaatt ccagatgatg caaagacgga
     9181 ttcctgtccg caatctgctc attatcctag cagttgttgc ggtgtccttc tttttgctct
     9241 tgacagtggt gtctcagtca ctagctgttc tgtttgcgac gctacttggt tgtagcatgg
     9301 gggtggtttt agatggtcag taagtatctt ttattagcag ttattttctc tggcttggtg
     9361 acttggattc cccgtatgat tccctgcatc ttagtcaagt ataagggctt gcctgcaatc
     9421 gttgagcgtt ttttgaagtt cttgcccgtt tccattatct ttgccttgat tctttcaagc
     9481 gtagtgacag gtaaggttgg gagccttcct caaattaaat ggctagactt cttagccgtc
     9541 tttccaacag cttgggtagc ctttcgctac cgcaatctag tcggaacagt tctctttgga
     9601 gtagtcttga ttgccatctt gcgtttggcc ttttaaatca actataaaaa aaacttatca
     9661 cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt
     9721 ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc
     9781 tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag aaggagaagc
     9841 agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaagccat ttatctatga
     9901 agaaaatggc gaattgactg gttatgagat tgaagtcgtt cgcgctatct ttaaagattc
     9961 tgacaaatat aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga
    10021 tgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa
    10081 atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga
    10141 ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac
    10201 tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct
    10261 taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga
    10321 ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag gtttggacaa
    10381 cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca
    10441 gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg
    10501 aacgcttgaa aaattgtcta aacaattctt cggagacact tacctaccgg cagaagctga
    10561 tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc tcagttttta
    10621 gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa atcaaacaaa
    10681 ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg
    10741 gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc
    10801 agaaaagaaa gcagacaatg caacaactat caaaatcgca actgttaacc gtagcggttc
    10861 tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga
    10921 atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga
    10981 tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga
    11041 ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg
    11101 aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc
    11161 gaatgacgct acaaacgaaa gccgtgcgct ttatttgctt caatcagctg gcttgattaa
    11221 attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa
    11281 cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc
    11341 tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga aatcactttt
    11401 caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg caaaaaaaga
    11461 ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt accacacaga
    11521 tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag tttggtaata
    11581 agaaacaggg aggtgggaga gagaattcca cctcttgctt ttgtatagag catggagtgt
    11641 aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga
    11701 acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg ttttgcgtac
    11761 cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta
    11821 tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc
    11881 gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta
    11941 taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac
    12001 gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca agggtcatat
    12061 cacagctcgc ttgagtgctt tgagaaaata tatgcagcgc catgatgatt tacctgtcaa
    12121 tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag ataagtattt
    12181 ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa
    12241 aaatgccttg gaacaactgg aaatttctgg tggcaataag gggattgtga cctttgatgc
    12301 caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggcgttg tggaatcagc
    12361 tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt
    12421 tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac
    12481 ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt
    12541 acaggaggat cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga
    12601 aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag
    12661 tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat
    12721 tcggaaacag ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga
    12781 gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggctaa
    12841 gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag ggcctatgca
    12901 tacggtcttt gatgccctag aggtgccaat ggtggccttc ggtctaggaa atgccaatag
    12961 tcgagatcac ggtggagatg aaaacgtgcg aatcgccgat tactacaccc atattgaatt
    13021 agtagaggag ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg
    13081 tgacttttca ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc
    13141 aagaagggga tatctacgga atcgttggat attctggagc agggaaatca acccttgtac
    13201 gggtgattaa tctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga
    13261 tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg
    13321 ggatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct
    13381 ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt
    13441 tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc
    13501 aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag
    13561 acgagtcaac ttctgccctt gaccctaaga caaccaagca gattttggcc ttgttgcaag
    13621 atttgaacca aaaattagga ttgacagttg tcttgattac gcatgaaatg cagattgtca
    13681 aagacattgc caaccgtgtg gcggttatgc aggatgggca tttgattgaa gagggaagtg
    13741 tccttgaaat cttctcaaac cctaaacaac ctttgactca agactttatc tcaacagcca
    13801 caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg
    13861 aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga
    13921 atgaattgta caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc
    13981 tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg
    14041 caggtgccca agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggagtac
    14101 agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct
    14161 ggtcaggcag gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttc
    14221 attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac agcgccaggt
    14281 ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt
    14341 gcggttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa
    14401 acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt
    14461 gctcgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa
    14521 gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat
    14581 ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt
    14641 gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat
    14701 cacgatgtga ccatcttggc aaccatcatt atcattttga ttatctttgc aatccaattc
    14761 ttgggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgc gtggctcttt
    14821 ttaactgatc agattttctg tgcaaatttt ttactcaagg cttgtccaat caaggcaccc
    14881 actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg gtttggagcg
    14941 accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt agccatatag
    15001 gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc gaaaataatg
    15061 aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac tccatctgct
    15121 aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa
    15181 aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac ttttgcgact
    15241 aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata aaacatgttt
    15301 ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag gaagtaaagg
    15361 actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct gataattttt
    15421 tcacaattct cattttacca tggtttggtg ggattgtaaa tggatactag aagtttttga
    15481 aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata tcatgggtag
    15541 atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag ccttcttttg
    15601 gctattaact ttagcaggag ggattatcct tggtctagcg ccggctagtg ccaccttgat
    15661 gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg aggcttggtc
    15721 tctttacaag caaaatttta tctcaagcaa cctgattttc tatagctttt taggtgtggg
    15781 tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga ccattgttca
    15841 tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg cttatacagt
    15901 atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca aattatcctt
    15961 gattggcatc tttatgagtc tagcagctgt ggccaaggtt ctccttggga ctgtgctact
    16021 tgtagcaatt ggttactata tgcctgctct tcttttcttt gtaggaattg ggatgtggca
    16081 tttctttatc agtgatatgt tggaaactgt ctatgaaatc atccatgaaa aattggcgac
    16141 aaaatagaat gaagcagttt tggctacata cgcttctaag aacctatagt tcagtgatga
    16201 tcattattat tgcgagtttt gcaatcttac tctctcacgc tgactgggat tcacgtgaaa
    16261 aggaagccca gagagtagtc cagcgtgtaa ctgctaattg aatattacca tagagagtca
    16321 acccagatag ctcagacttt agttgaaaat caagctcgta ttgagggaat ctataaatac
    16381 tttagcctta gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat
    16441 atatcagtct ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact
    16501 ggagtggcca tcgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt
    16561 agtggagaaa aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg
    16621 atgtcagatc cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct
    16681 gttttatacc atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc
    16741 tcaccttttg atacggagat ttttcatatt ggtgagacag ttgataagga gagtgaaaat
    16801 tggctcgttg gcttaacatc tcatggctat caggttcagg tggcagttcc taaaaacttt
    16861 gttttacaag gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt
    16921 gtcattcttt atctgacttt gaggcatact tttgctaatt accaaaagca ggtagtggat
    16981 ttagtagaat ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc
    17041 gaaaaagatc aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg
    17101 gaaaagaata tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga
    17161 gccttgcagg cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg
    17221 tatgcagtta tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc
    17281 ttgcgtaaca atatttccga cgaaagagag acccttctca aacaggaatt agaattttgc
    17341 cgtaaataca gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag
    17401 atagatccag agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa
    17461 aactatttcg cgcatggtgt tgaccacagg aggacagata atgtgattag catcaaggct
    17521 cttaaacagg atgcttttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct
    17581 gaaaagttgg caaatatccg agaaaaatta agtcagagat attttgaaca ccaagccagc
    17641 tacagtgatc aaaggcagtc tatcgggatt gtcaatgtac acgagcgttt tgtgctctat
    17701 tttggagacc gctatgccat tacgatagag tctgcagagc aagccggtgt tcagtatcgt
    17761 attacaattc aagatgagta gaaagggaga aaatgtataa agtattaata gtagatgatg
    17821 agtacatggt gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gacatggagg
    17881 ttgtcgcaac agccagtcat gccgatgaag atctagaata tgttcaggaa aatcctgtcg
    17941 atgtcatcat ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga
    18001 tgaaagagat cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt
    18061 atgtaaaaag agcaatgaac cttagtgtgg tggactattt ggtcaagcct gttgataagg
    18121 tagagctggg aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa
    18181 gtcagactct tagtcaagaa ttagacgggg ctggatttgt tagttattta ggggataagg
    18241 agaattggtg gataggtcta tccaaggaaa aacaaggttc cttcaccact ccctactatg
    18301 tcttgggtca agactggcag attttcattt ctgaccaacc cctagatggt ttagtcgtta
    18361 caccttttga agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaag
    18421 ccctctttta cggctctgta aatctgcagc agtctgagag tctctttgcc tattacgaac
    18481 cgatttatag ggttatcatt cagggaaatc tcaatcaaat cgtagaagag ttaaatcttt
    18541 tggagaaggt agttcttgaa aatacacctc gtgttccgat taccaaacag ctttttattc
    18601 agtttgtcat ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca
    18661 tcgtcaaaac ggttcatgct attcaatcct tcgatgaatt ggttccttat atcaaggaaa
    18721 ccctgaccag cttttttggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag
    18781 ttattgggcg tgattatcag aaagaacttt ccatcaagga tatcagtaag gatctcttta
    18841 tcaatcctgt ctatctaggg cagtcgatta agcgagaaac cgattcgact tttgcagagt
    18901 tactaaacaa acaacgtatt aaggctgccc aacaactttt gctttcaact agtgatagca
    18961 tcgaagatat ttgttatgct gttggttaca gtaacattgg atatttctat aaagttttcc
    19021 gaaaattgtg cggaaaattg ccaaaagcct accgaaaaca ggtagaaact atactataag
    19081 atttgtattc ctttacaaaa ggtgctataa tataaataat attatcagga ggttctatca
    19141 tgaaaaagaa accaatttat ctatgggtct tgctaatctt gtctgccctt atttcagttc
    19201 cgtctctgtt tggaattgtg agtcccttgc ctagtaaaga agcccttcgt gctgctcaga
    19261 aacaagttgc aggggtcaat gctcagcaat tagaagacca gcttaattat acctatagag
    19321 tagtagaagc atctcattct atttttaatg ttgctttgat tgtgctatct actattttag
    19381 tggtcgtagc gattgtcttc cttgttcgta aaaatttgca atatgcaaac tatacttacg
    19441 ttggctatgt tttgttagct attattggtt cgatttatag ctatgttggt ttacaagacg
    19501 ctgtgcagtt ggttcaagat gagagcatgc gtttgacaat gagtattggt tcaaaagctg
    19561 ttagcatttt ctatatcgtc atcaatgttc tcttcttagc ccttgtcttc tataagatgt
    19621 ggcgacaaca gaaagccttg gcagaagaag aggaaacaga agagcttgcc taagtattga
    19681 caaaaaagaa ctatcaagat acaatcttgg tagttctttt tcgattatag ataaaatcat
    19741 ggaggtacat atgaagacaa tttctttagt ttatattagt ttgagtggca acattgaaag
    19801 ttttgtgacg cgcttgaaag actatctctt gtcccagtac aaagggattg aggttcaaaa
    19861 gattcatatc aaggatttgg tcaaggaagg caaaaatttc tatgaaatgg accatcccta
    19921 tgtcgctttt ttgccgacct atctcgaagg tgggaatggc gtggataacg gagatgttga
    19981 gattttgacg acaccggtgg gagattttat tgcctatggt aacaatgcta gtaagtgttt
    20041 tggtgtggtt gggtcaggaa atcgtaactt taataaccaa tactgcctaa cagccaagca
    20101 atacagtcaa cgctttggct tccctgtatt ggctgacttt gaaatgcgag gcatgctgga
    20161 agatatcaaa cgtgtcgcag ctattatcgc agatttgtat gagttggaaa aggagaatta
    20221 atactcaatg aaaatcaaag agcaaactag gaagctagtc gcaggttgct caaagcacag
    20281 ctttgaggtt gcagatagag ctgacgtggt ttgaagagat tctcgaatag tataaagttc
    20341 ttataagagg tggttgaagt ttttcaactg ttttttgagt ataaacagtc tttaagaacg
    20401 taaaaaagca taagttcagg tcttcaaaac cttgttctta tgctttttat catagaaata
    20461 tttgctgaat tttctcttga aatgaaacct tatcttcatc tcgcgcttgt cccttaccct
    20521 gcttttccga ttgcgagtgc gtagataaag aagatggcga agccaaagag gaaaatcaat
    20581 cccacaatgg caaggtgttt gaggcaagaa ggaagatttt tgttttcacg cgttaccaag
    20641 gcataattca aaagagcaaa gaaaggtgtt gtcaggaaag agccaatcat ggcaaagcgg
    20701 agcatggttg aaacctgacc agcgaagaac ttgataatga cgataccgat gatagcagtg
    20761 atggtcatcc agatgttcaa agatttacga ttgtcctctt tttgactgat tagcagtcgg
    20821 agagattctt ggttaacgcg agaatagcca tcgataacag tgataactgt tccaaagata
    20881 cacaggaaag caataaaggt aatcaagtaa cgggaccatt cgccaagaac agaggcatac
    20941 atgcccacga attgagagat gtatttggct gaagcagctt caaccgcctg ccctgtagga
    21001 tactgaatca gtgctcccag tgccacaaag aagacggcta ggatagctgt tccaatataa
    21061 ccagtgttaa agtcaaacag agcgtcttct ttgttaaagt tgacggtttt tctcttttca
    21121 gctgaccaaa gtgaattgat agctgaaatt tcaataggag caggcatcca tcctaggagg
    21181 gagacgatga agggcagagc tgccatttgc caaggtgtct tctcgacaaa atcagaactg
    21241 tattctggat gcttgaccgc tgctatgata actgcaagaa cagttgcaat ggttaaggca
    21301 gacataatcc atttgaccat gccgtctaaa agtttgtagc ctccaaagag tagcatagcc
    21361 caaatgattg caacgagaat gagggaccac tgagtaatgc taagtccaat cattgggaag
    21421 gcactggcga tgatagctga gcacagaatg gcaacaccag ccgtgttgac catagcagaa
    21481 aagacattga ggataaagaa aatccagaga tagagttttc ctttttcggc ataaccttca
    21541 accaaagtct ttccagtatc agctgtgtat tcagcaccaa aacggaaaaa tggatattta
    21601 aagacattgg ctaagatgac caagagaagt agagaccaac cgtaagaacc gccagcttga
    21661 gttgaggata caatgtggga acctccaaca gcggcagttg ccattaggat tccaggtccc
    21721 attgctttta gcttgcttgc ccaggttgat tgatttaagg aaatagcttg cgacatgata
    21781 aatactcctt tttgaatttt cagaataatc tgtatatgta atttatattc tacaaaaaat
    21841 tttggaaaaa tgcaagaata ttttaaaaaa atatagaaaa tttacaaaga agatctgaaa
    21901 ataactgtta tgatatagta gattgaaact agaatcgtac acctctgctt ctaaaatatt
    21961 gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttgtttca tttcactata
    22021 gtaaggtgca gcaggataaa gaaaaaccga gaagtttctt tctcggattt gcttattacg
    22081 aggttcctat tttctatgct ccaagagttg attgatgtga tctacttttt tagcctctct
    22141 tttatagaga atagcccaga tgatgagata gacaatcgca aactcgataa tgagctggag
    22201 gtagaaaatc cagtggaagg ggaaccaacc agctagggtt gctagtggga caaagccagc
    22261 catcataagg aagaaatgag tcagagtggc acgaagcatg ctccagtcac ggctgaataa
    22321 gtggttgccc aagttgaaga gcataccgat agctgcccaa ataagtgtac agtagagcaa
    22381 gaccagggca ccgtgaacct gatgctgatc catcacttgg ccgatgagag agtagggatt
    22441 tagtggtgcg taggtatttg gtgcataaat gagcgaaaag aggatagaga ggatgaggcc
    22501 gataagaaca tcggcagctg catcgtgaaa tacttgtttt ttcatagttc taatttctcc
    22561 ttgatggttt ttaggtaacg gcgtgaagag taggtgaagc tttcgttttt caagaaaatt
    22621 tctaccaggc cgttgggggt tagcttgaga tgagagatgg agttgatatt gatgatttct
    22681 gattgggaaa tttggataaa actggttggt aagcattcaa gaacctgata gagtcgcaaa
    22741 tcaatgctgt aggtctgact tgctgtttct gctagaacct tccgattctc gatatagaag
    22801 cattgtatct taccaatctt aacgagatag acctgatcat caatctttcc tttgattgtt
    22861 tctctttggt ctagattttc tgcgaactcg atgactttct ggactttttc ggtttcttga
    22921 ggtgcttgga caatcagctt ttcctcctcg taagtctcac taatctgtag ttctactttc
    22981 atagttttct ctccttttca gttatacaag gttgtgatca cttcctgtat atccttatta
    23041 aacactattt tatagcccat ggcaagggac tttgtctatg tggagggatt gggctcctat
    23101 gtggtggagc ttttctgttc tttctgaaat atggtataat agcactaatc aatttctagg
    23161 aaaatagata cagaaagggg ctgaaagatg tctcatatta ttgaattgcc agagatgctg
    23221 gcaaaccaaa tcgcagctgg agaggtcatt gaacgtcctg ccagtgtggt caaagagttg
    23281 gtagaaaatg ccattgacgc gggctctagt cagattatca ttgagattga ggaagctggt
    23341 ctcaagaagg ttcaaatcac ggataacggt catggaattg cccacgatga ggtggagttg
    23401 gccctgcgtc gccatgcgac cagtaagata aaaaatcaag cagatctctt tcggattcgg
    23461 acgcttggtt ttcgtggtga agccttgcct tctattgcgt ctgttagtgt cttgactctg
    23521 ttaacggcgg tggatggtgc tagtcatgga accaagttag tcgcgcgtgg gggtgaagtt
    23581 gaggaagtca tcccagcgac tagtcctgtg ggaaccaagg tttgtgtgga ggacctcttt
    23641 ttcaacacgc ctgcccgcct caagtatatg aagagccagc aggcggagtt gtctcatatc
    23701 attgatattg tcaaccgtct gggcttggcc catcctgaga tttcttttag cttgattagt
    23761 gatggtaagg aaatgacgcg gacagcaggg actggtcaac tgcgccaagc aatcgcaggg
    23821 atttacggtt tggcgagtgc caagaagatg attgaaattg agaattctga cctagatttc
    23881 gaaatttcag gttttgtgtc cttgcctgag ttgactcggg ctaaccgcaa ttatatcagc
    23941 ctcttcatca atggtcgtta tatcaagaac ttcctgctca atcgtgctat tttggatggt
    24001 ttcggaagca agcttatggt tggacgtttt ccactggctg tcattcacat ccatatcgac
    24061 ccttatctag cggatgtcaa tgtgcatcca actaagcaag aggtgcggat ttccaaggaa
    24121 aaagaactga tgactctggt ttcagaagct attgcaaata gtctcaagga acaaaccttg
    24181 attccagatg ccttggaaaa tcttgccaaa tcgaccgtgc gcaatcgtga gaaggtggag
    24241 caaactattc tcccactcaa agaaaatacg ctctactatg agaaaactga gccgtcaaga
    24301 cctagtcaaa ctgaagtagc tgattatcag gtagaattga ctgatgaagg gcaggatttg
    24361 accctgtttg ccaaggaaac cttggaccga ttgaccaagc cagcaaaact gcattttgca
    24421 gagagaaagc ctgctaacta cgaccagcta gaccatccag agttagatct tgctagcatc
    24481 gataaggctt atgacaaact ggagcgagaa gaagcatcca gcttcccaga gttggagttt
    24541 ttcggacaaa tgcacgggac ttatctcttt gcccaagggc gagatggact ttacatcata
    24601 gatcagcacg ctgctcagga acgggtcaag tacgaggagt accgtgaaag cattggcaat
    24661 gttgaccaga gccagcagca actcctagtg ccctatatct ttgaatttcc tgcggatgat
    24721 gccctgcgtc tcaaggaaag aatgcctctc ttagaggaag tgggcgtctt tctagcagag
    24781 tacggagaaa atcaatttat tctacgtgaa catcctattt ggatggcaga agaagagatt
    24841 gaatcaggca tctatgagat gtgcgacatg ctccttttga ccaaggaagt ttctatcaag
    24901 aaataccgag cagagttggc tatcatgatg tcttgcaagc gatctatcaa ggccaatcat
    24961 cgtattgatg atcattcagc tagacaactc ctctatcagc tttctcaatg tgacaatccc
    25021 tataactgtc ctcacggacg tcctgttttg gtgcatttta ccaagtcgga tatggaaaag
    25081 atgttccgac gtattcagga aaatcacacc agtctccgtg agttggggaa atattaaaag
    25141 tataaaaaag tctgggaaaa atgttcaaaa tcagaaaaac gcataaaatc aggtgttcaa
    25201 aaaccttgat tttatgcgtt ttatcataga aatatttact tcatgttttc ctaattcttt
    25261 tcgaaactct ttttaaacca cgtcagtttt atcagtaatc ttaaaacagt gttttgagct
    25321 aattttgcca gttttgtctg taacatcgaa gttgtgtttg accactctgc gactggtttc
    25381 ctagtttgct ctatgatttt cacagagtat taaattgcga ttttgccaag tttctttatt
    25441 cgtctaaaag tagagtctgt tctatgcgtc taatgtacga attaggttga ccatttcaat
    25501 agctccttgt gcacactcag aacccttatt tcctgcttta gtgccagctc gttctatggc
    25561 ttgttcaatt gtatctgtcg ttagcacacc aaacataaca ggaatttcgc tatttaaact
    25621 gatttgggcg attcccttag atacctcgct acatacataa tcataatgac ttgtattccc
    25681 tctaatgaca gctcctaagc agataattgc atcatatttt ttactttttg ccatttttga
    25741 tgcaatcagt ggtatttcaa aagctcctgg aatccaggct acctcgatat ctttctcgtt
    25801 tacattctct cttttgagat tatctagtgc tccagataat aattttgaag ttataaattc
    25861 attaaatctc gctacaacaa tacctatttt aatattgttt gctactaaat taccttcata
    25921 agtgttcatt tatttttcct ccatatttaa aatgtgaccc attcgatttt tctttgtttc
    25981 taaataaaaa ctatcgtaag cattggcttc tatttcgatt gatattctac tggaaatggt
    26041 aattccatat ttttctaact gttcaacctt gtcaggatta tttgtcagta aatgaagtga
    26101 ctgaagtccc agatctttaa gtatttgtgc tccaatatgg tattctctta aatcaccttc
    26161 aaagcctaat gcaagattgg catcaagcgt atccatgcct tgatcttgta aatgataggc
    26221 ttttaattta ttgataagtc caattcctcg tccctcctgt cgcaagtaaa gtaagacacc
    26281 cgaaccattc tcaacaatca ttttcatagc tttatcgaat tgctgtccac aatcgcaacg
    26341 taaagagcct aaaacatctc ctgttaaaca ttcggagtgg acccgacata atacattggc
    26401 ttcatcctct atatttccca taataagagc aagatgatgt tccccattta gtttatctat
    26461 atagctaatt gctttgaaat taccgtatct agtaggcata ttgacagttg aaactcgttc
    26521 taccagctga tcatatactt ttctatattc ttgtaattct ttgatggtaa ttagtggaat
    26581 gttgtgtttc ttcgagaact gaattaaatc atctgttctc atcattttgc catcatgatt
    26641 cattatttca caacataggc cacactcttt tagtccagct aattttaata aatcaacagt
    26701 tgcttctgtg tgtccatttc tttctagaac accacctttt ttttcaatta aaggaaacat
    26761 gtgtcctggc ctgcgaaaat cagagggtgt tatatcttca gctacacaca tacgtgcggt
    26821 cagtcctctt tcctcggcag aaatacctgt ggtcgtttct ttataatcaa ttgaaactgt
    26881 aaaagcagtc ttatgattat ctgtattgtt ttcaatcata ggtgaaagca ttaattgatt
    26941 agctaaactt tcgctcatag gcatacaaat taatcctttg gcataagtag ccataaaatt
    27001 aacattttct gttgtagctg cttgtgcaga acaaattaag tctccttcat tttctctatc
    27061 cttatcgtct ataacaagaa caagtcgtcc cttctgcaat gcttctaatg cttcttgtat
    27121 ttttcgatat tccattgact gattatcctt tctgctaaaa tccattttga tataatagtt
    27181 ccttagatat ttctgatttt ggagaattat ccatcagttt ttgcacatat ttacctaaga
    27241 tatcattttc aagatttact gtactcccga cttgtttact cttaagaatg gtttgttccc
    27301 aggtatgagg gataacagat actgaaaagt ttactttgga gactttagcg acagtcagac
    27361 taatgccgtc aattgtaata gatccttttt caactattaa atctaaaatt tctttttgtg
    27421 tgttgatttg ataccataca gcattatcat ctttttttat tgacgagatt tttcctgtac
    27481 catcaatgtg tcctgtaacg acgtgacccc caagtcgacc gttgacagat aaggctcttt
    27541 ctagattcac ctcacttcca tgttttaata gagtaagagc tgttcgactc catgtttcat
    27601 tcattacatc aactgtaaag gattgatgat tgaaatgagt aactgtaaga cagataccat
    27661 ttactgctat actatcacct aaatggatat ccgttaatat ttttgaggct ttaattgata
    27721 gtttacaatt acgagagtct ttctgtattc tttcaacttt tccgatttct tcaattattc
    27781 ctgtgaacat ggataaatca cttcactttc tatgagatag tcatttccta tttgagaaaa
    27841 agcataaggt ttcaatctaa tagcgtcatt tggcaaagaa atgccttcac ctccgatagg
    27901 aaacttggca ctgcctccaa aaatttttgg tgcaatatat attttcagct catcaacaat
    27961 ttgttgttcc aaagcactcc aattcattag actgccccct tctagaacta ggctatcaat
    28021 ctgcatgttt cctagatgtt gcattaaact cgataagtct atatgattgc cttttttctt
    28081 tatggaaagt attttacagc catgattttg atatagcttc attttatttt tgtcttcaga
    28141 ggaagtggca atgtaagttt taatatcatt tgctgttttt acgattttag aggtaagagg
    28201 agttcgtaaa tgtgtatcgc atatgatacg gataggattt ttcccttcct ccaatctaca
    28261 tgtcagcaaa ggatcgtctt gaataacagt gttgactccc accataattg cactaacatg
    28321 gtgtcgtaac tgatgcacat gctttcttgc ttcttcttca gtaatccatt tggattgatt
    28381 tgttttagtg gctatttttc catccattga cattgcatat ttcataaaaa catagggtac
    28441 atgctgggta atatactttc taaaactttt tattaagtta agacactcat tttctaaaat
    28501 tccaacagta acttgaagat tattttcctc aagtatcttt actccttttc cagatacaat
    28561 aggattacag tctaggcttc caatgactac tcttgtaata ccactatcga ttatagcatc
    28621 tatacaggga ggtgttttcc cgaagtgaca acagggttca agtgttacat aaagcgtcgc
    28681 tccgacaggg gattctctac agtttttaag agcatttctc tcagcatgtg ggccaccaaa
    28741 aaactcatga taaccttgtc cgatgatgtg attatctttt acaataactg cgccgaccat
    28801 aggattgggg ttgacgtaac cagccccttt ttgtgccagt tttattgcta atttcatata
    28861 ttttgaatcg ctcatctcac tacctccaaa aaatatacct tgaatagggg actactcaag
    28921 gcatacaaaa gaaaacttat gcgattaaca aaaatgctct gaaatgacaa gtaatcattt
    28981 cagagcacgc aaaaagcaca aatatacttt tatcttcttt catccagact atactgtcgg
    29041 ctttggaatt tcaccaaatc atgcctttcg gctcgtgggc tataccaccg gtagggaatt
    29101 gcaccctgcc ctgaagatag ttattcaatt acagatgatt atagtactta attttgaata
    29161 tgtcaacaga taaataccga ttgtttttga tatactgtat ttgtgataat cgattctcgc
    29221 tcctcggata aagaaaatat gatatactag ataaacgaaa taagagagaa ggaatactat
    29281 gtacgcatat ttaaaaggaa tcattaccaa aattactgcc aaatacattg ttcttgaaac
    29341 caatggtatt ggttatatcc tgcatgtggc caatccttat gcctattcag gtcaggttaa
    29401 tcaggaggct cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg
    29461 atttcgctca gaggatgaga aaaagctctt tcttagtctg atttcggtct ctgggattgg
    29521 tcctgtatca gctcttgcta ttatcgctgc tgatgacaat gctggcttgg ttcaagccat
    29581 tgaaaccaag aacatcacct acttgaccaa gttccctaaa attggcaaga aaacagccca
    29641 gcagatggtg ctggacttgg aaggcaaggt agtagttgca ggagatggcc ttcctgccaa
    29701 ggtcgcagtg caagcaagtg ctgaaaacca agaattggaa gaagctatgg aagccatgtt
    29761 ggctctgggc tacaaggcaa cagagctcaa gaaaatcaag aaattctttg aaggaacgac
    29821 agatacagct gagaactata tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag
    29881 aatgacaaaa cgttgttcgt gggtcaagat gaccaaccca ctctacatcg cctatcatga
    29941 tgaggagtgg ggccagcccc tccatgatga ccaagcgttg tttgagttgt tgtgtatgga
    30001 aacctatcag gcaggcctgt cttgggaaac ggtactcaac aaacgccaag ctttccgaga
    30061 agcctttcat agctatcaaa ttcactcagt cgcagagatg actgacactg aattggaagc
    30121 tatgctggag aatccagcta tcattcgaaa tagagccaag atttttgcta cacgcgctaa
    30181 cgcccaagcc tttctacagt tacaggcaga gtacggctct tttgatgcct atctttggtc
    30241 ttttgttgag gggaaaactg tcgttaacga tgttcctgat tatcgccaag ccccagctaa
    30301 aacaccctta tctgagaaat tagccaaaga tctcaaaaaa cgaggcttca agttcacagg
    30361 cccagtcgcc gtattgtctt ttctacaggc tgcagggcta gttgatgatc acgagaatga
    30421 ttgtgagtgg aaaggtctta aatgatgtct aacaaaaata agggaattct gatttttgcg
    30481 attctctata cagtcctctt tatgtttgat ggcgttaaat tgctggcttc tttaatgcca
    30541 tctgccattg caaattatct tgtttatgta gttttagctc tatatggctc cttcttgttc
    30601 aaggatagat tgatccaaca atggaaggag attagaaaga ctaaaagaaa attcttcttt
    30661 ggcgtcttaa caggatggct ctttctcatt ctgatgactg ttgtctttga atttgtatca
    30721 gagatgttga agcagtttgt gggactagat ggacaaggtc taaatcagtc taatattcaa
    30781 agtacctttc aagaacaacc actactgata gctgtttttg cttgtgtcat tggacctctg
    30841 gtagaagaat tatttttccg tcaggtctta ttgcattact tgcaggaacg gttgccaggt
    30901 ttactaagca ttattctggt aggacttgtt tttgctctga ctcatatgca cagtttggct
    30961 ctatcagagt ggattggtgc agttggttac ttaggtggag gccttgcctt ttctattatt
    31021 tatgtgaaag aaaaagagaa tatctactat cccctacttg ttcacatgtt aagcaacagc
    31081 ctctccttaa tcattttagc tatcagtata gtaaaatgaa atgagaacag gacaaatcga
    31141 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatata ctgtaatatg
    31201 tgatgaaaat gccagtaatg ataccgagaa aaaagctgag aaacttttcc cagctttatt
    31261 tgttatagtc aaagagaatg acttgttcct gtgcatctac atgagcatgg accccaaagg
    31321 gtacaattgc tcttggagtt gcgtggccga cattcagatt atagacaatc gggatattgc
    31381 tgtcaatgat atccaatagt gcctctttat agtcgtcatg gaaagtttca tccataggtt
    31441 ttccgaccaa gagtccattg atgaccgcga atatgccagt gtcctttaaa gttagcaaca
    31501 tctttttgaa gtcttctggc ttaggctttt cttcgcttgt ttcgagcaag aggattttcc
    31561 cttcccagtc tgacaagtca gggaaaagtt tgtatttttg gcagagctcc gtgctatctg
    31621 cgtatcgaga gttgtcaaag atatcgtaga gggattcgag gcaaccaccg aggattttcc
    31681 cctcgaactg ggcacttcct tgcaacaagt caaaacctgt atttgtatga ctgacacgag
    31741 gtgttcccag ggccgtggga ctaaaatcag ttcgttcctc ataccaaacg tcactagggc
    31801 ggatttctga aattcttccc gtctcaatca attctttaaa gtagtgaagg ctataggcta
    31861 gcatttcttt gtctaattca caaatgtctg ctaaaaagga ttgaccataa aaagtcttga
    31921 ttcctaattt atgcaacatg aggtggttca tggttgtatc cgagaagcca agaaaaattt
    31981 tttgtttgat aaccttttgg agttggtcat tttcaaaaag ataaggtagc aagcgatagg
    32041 tatcgtctcc accgatggca cataggatca tgtcgatgct atcatcagaa aaggcatgaa
    32101 tcaaattctc tgcacgagct tcaggatggt ccttgataaa gtctaatcct tttaacgaat
    32161 ggggcaaaaa gatgggattg agtctcagat ccttgagacg ttggataccc aagtccactt
    32221 cgtgtttgac aaaatcctct ccgataatgc cactagataa actaacaata ccaatagtag
    32281 aaaccatatc tcatcctcct agaaatagat tgagcctatt ttatcacaaa atataagaga
    32341 aagctatgtg ggatttcaga agaatacttt taatactctt cgaaaatctc ttcaaaccac
    32401 gtcagtttta tttgcaacct caaagctgtg ctttgagcaa cctgcagcta gcttcctagt
    32461 ttgctctttg attttcattg agtataactc aaaaaagtaa gtgaaaaagc aaccgcacct
    32521 gcagttgctt ttatcgtttt cttattcttg atagcgtgtt ggtcctgcac ttgcactacg
    32581 gatattcaag cgtttcttga gatagaagcg aagggctagg agggctgctc caataatagc
    32641 tagtggcaat ggatccagta ctgggttaag gctagctggt aggaagcttg ttgcaaagaa
    32701 gacaagcaac caaaggaaca tagaagctag gataactagt acagatttcc agaaaggtgg
    32761 acgttgactg cgatccatat ctggtccata gtattggtaa acaaagtagt acatcaagta
    32821 gaaggcaaat ccaccaacca gtccaactaa tagaagagta atcaatccat agccgaaagc
    32881 ttgatctgcc gcaaagaagg ttgtgagggc gctgacaagg gcaaagaggc tagtgatgaa
    32941 aagagctgag tccataatca tcagttttgg atcatcattt tcttttggat gctctttttc
    33001 gtactgctct ttgacagtga agctatgagc ccaatgagtt ggtgcgccgt atagggaacg
    33061 ggcagttgta cctttagatt gctcctcaag gatttgggga atgacttcct caaaaatagt
    33121 ctggatttca gcgtctgttt tcccatcttt gatgaattgt tgggtagcaa tgtggacaaa
    33181 ctcttggttt ttcttagtta atttttgtag atcaatttga gacataggaa ctcctcttag
    33241 aaccattttt tatggatgag atagagagtg agcgagacac tcatagcaaa ggcgataaag
    33301 acgattaacc agaaggcatt tggctctccg tttaggggga tttcattatc cttaaagttc
    33361 atcccgtagg cagaaaagac catggttggg atggacatga cgatggtcac aagggccaag
    33421 gttttcatga tgttgttctg gttgttagaa atgatagagg caaaggtctc tgtcatagaa
    33481 tgcaagacgt ttccataaat atctgccatc tcgatggcct gttgggtttc aatcagggtg
    33541 tcttcaagca ggtcttcgtc ctcaaggtat ttcttgatat tgctggttga actggtcaat
    33601 ttcttaatca cgcgctcatt tgttttgagg gaggccttga aatagacgat agttttttcc
    33661 aattccatga gctcaatcaa ttcttcatta cgagttgatt gatgcagttg actttcgatt
    33721 tgttcactct tgcggtcgat tgaacgaagg gctgttaggt aaagctctgc attgcgataa
    33781 agaatttgaa agataaaacg tgaacgcatg aaggtataga aattacgcaa tcgacggttg
    33841 ataaagacat caaggacagg tagtggttcc aaacacgtag tgataatggt ttcctcagtg
    33901 atgataatac caagcgggat ggttacgtag taggtgcggt tatttctttc ctccgtgacc
    33961 ggcacgtcta cgataatcag ggtatactcg tcttcaatgg taatacgaga catttcttcc
    34021 gcatcgagcg gtgctcgaag gtcggcaata tcaatatcga aggtgttggc gatttcgagt
    34081 gattcatttt gagtcggatt gacgagattg atccaagtac ccggttcaag cgtatcgatc
    34141 tctttaaatt cagttgttgt agagagaaaa acttgtttca tatcccttat cctttctcat
    34201 ttttcagatt ttttcacact gtactattat actacaaaat cggccttttg ggtaatagaa
    34261 tctcactttt tttggtataa tggtaagcaa taatggacta gaaagaacaa agatgcaaga
    34321 taaaattgtc attcatgggg cgcgtgccca taatttaaaa aatattgatg tggagattcc
    34381 gcgagacaag ttggttgtcg tgactggctt gtcaggttca gggaagtcca gtctggcttt
    34441 tgataccctc tatgcggagg gacaacgtcg ctatgtagag agtttgtccg cctacgctcg
    34501 tcagttcttg ggaaatatgg aaaaaccaga tgtagatgcc attgatggtc tcagcccagc
    34561 tatttccatc gaccagaaaa cgactagtaa aaatcctcgc tcgacggtgg gaacgacgac
    34621 tgaaatcaat gactatctgc gtctcctcta cgcacgtgtg gggacgcctt actgtatcaa
    34681 cggacatgga gctatcaatg cttcttctgt ggagcaaatc gttgataagg ttttggagtt
    34741 acctgaacgc cagcgcttgc agatcttggc tcctgtcatc cgcaagaaaa aaggccaaca
    34801 taagagtgtt atcgagaagg ttcagaaaga cgggtatgtt cgtgtccgtg tggatgggga
    34861 agtctatgat gtgaccgaag tgccagagtt gtctaagagc aagcaacaca atatcgatgt
    34921 cgtggttgac cgtattgtta tcaaggaggg cattcgtagc cgtctctttg attccattga
    34981 agctgccctt cgtatcgcag aaggttatgt gattatcgac accatggacg attcggagtt
    35041 gctcttctct gagcattatg cctgtccagt ttgtggattt actgtcccag agttagagcc
    35101 tcgtctcttc tctttcaatg ctccctttgg ctcttgtagt gagtgtgacg gcttggggat
    35161 taagctggag gtggatactg atttggtagt gccagatgcc agcaaaacgc tacgtgaggg
    35221 ggctttggca ccttggaatc ctatctcatc taactactat ccaaatatgc tagagcaggc
    35281 tatgacagcc tttggagtgg atatggataa gccctttgag gacttgtcag aagaagataa
    35341 gaacttgatt ctctacggct cggatggcaa agaatttcat tttcactatg agaatgaatt
    35401 tggcggtgtg cgcgatattg acattccttt tgagggagtc gtcactaata tcaagcgtcg
    35461 ttaccatgag actaacagtg attacacgcg cactcagatg cgtctctaca tgaatgagct
    35521 gacctgcgga acctgtcaag gctatcgtct caatgaccag gccttgtctg tccgtgtggg
    35581 cgaccagcaa gggccacata ttggagaaat ctcagacctg tctatcgctg accacttgga
    35641 cttggtgagc cagttaactt tgtctgaaaa tgaagccatc attgctcgtc ccattctcaa
    35701 ggaaatcaag gatcgtttga ccttccttaa taatgtgggt cttaactatc taaccctgtc
    35761 acgttcagca ggaacccttt caggtgggga aagtcagcgc attcgtttgg caacccagat
    35821 tggttccaac ctatcaggcg tcctctatat cctagacgag ccgtcaatcg gtcttcacca
    35881 gagggacaat gatcgcctga ttgccagtct gaaaaagatg cgtgacttgg gcaatactct
    35941 tatcgtggtg gaacacgacg aagataccat gcgtgaggct gattatctga ttgacgttgg
    36001 tcctggtgcc ggtgtttttg gtggtgagat tgttgcagca ggtacaccta agcaagtggc
    36061 tcgcaacagc aagtctatca caggtcagta cttgtcaggc aaacgtgtca tcccagtacc
    36121 agaagagcgc cgtgtcggaa atggtcgttt tattgaagtg ataggagcgc gtgagaacaa
    36181 cttgcaaaat gtcacggctc gctttccact aggaaaattt atcgcagtga caggtgtgtc
    36241 gggttcaggg aaatcgactc taatcaacaa cattctcaaa aaagccattg cccagaagct
    36301 caaccgtaat tcagacaaac ctggtaagtt taagactatt acagggattg agcatgtcga
    36361 ccgtttgatt gatattgacc agagccctat cggacggacg ccgaggtcta acccagctac
    36421 ctatacagga gtttttgacg atatacgtga cctttttgct cagacaaatg aagccaagat
    36481 tcgaggctat aagaaggggc gcttcagttt caacgtcaag ggaggtcgct gtgaagcttg
    36541 ctcaggtgac gggattatca agattgagat gcacttcttg ccagatgttt atgtggcttg
    36601 tgaagtttgc cacggaaccc gctataacag tgaaacccta gaagttcact acaaggaaaa
    36661 gaatatttcg caggtcttgg atatgacggt caacgatgcg gtagaatttt tccaacacat
    36721 tccgaaaatt caacgcaaac tccagaccat caaggatgta gggctaggct atgtgacctt
    36781 gggacagcca gctaccaccc tttctggggg agaagcccaa cgtatgaagt tagctagcga
    36841 actccacaaa cgctcgacag gaaaatcttt ctacattctg gatgagccga cgacagggct
    36901 tcatacagag gacattgctc gcctgctcaa ggttttagct cgctttgtag acgatggcaa
    36961 tacagtcctc gtcatcgagc acaatctgga tgttatcaag acggcagacc atatcattga
    37021 cttgggacct gagggcggtg tcggtggtgg aaccatcatc gtaacaggaa ctccagaaga
    37081 agtagctgcc aacgaagcca gctatacagg acactatttg aaaggaaagt tacatcatga
    37141 ataaacgcgt acaagcattt ctagctaaaa tgcaagaaaa agaactagat ggtatcatca
    37201 tcaacaatct taaaaacgtc tattatttga ctggtttttg gggctcaaac ggaacagtct
    37261 ttatcagccg tgaccgtcag gtcttagtga cagactctcg ctatatcatc gcagctaagc
    37321 aagaaaccag tggttttgag attgtggctg atcgtgatga attggctgtc attgtaggaa
    37381 ttgttaagga catgggcttg actcgtatcg gttttgaaga tgagatttca gtgtcttatt
    37441 accaccgtat gcaggcaact tttgcaggtt tggacttgct tccacaaact cagtttgtgg
    37501 aaggtcttcg tatgattaag gatgaggcag agattgcagc gattcgcaag gcttgtttta
    37561 tctcagacca agctttccgc gatgcgcttg actttatcaa accaggaaaa actgaaattg
    37621 agattgccaa cttccttgat ttccgcatgc gtgagttggg agcatctggc ttatcttttg
    37681 atacgatcct agctagcggt atcaattctt ctaaacccca tgcccatcca atgcacaaac
    37741 cagtggagtt gggagaagcc attaccatgg acttcggctg tctctatgac cactatgtca
    37801 gtgatatgac ccggactatc tatctagggc atgttagcga tgagcaggca gagatttaca
    37861 atacggttct aaaagctaac caagccttga ttgaccaagc taaggcaggc ttaggtttcc
    37921 gtgactttga caaaatccct cgtgatatta tcattgaggc aggttatggc gactacttta
    37981 ctcacggcat tggccacggt attggtctgg atatccatga ggaaccctac tttagccaga
    38041 cttctacaga aactattaag acaggtatga ccttgaccga tgaaccaggt atctatatcg
    38101 aaggcaaata tggcgttcgt atcgaggatg atatcctgat tacagagaca ggttgtgaat
    38161 tattgaccct agctccaaaa gagttgatag tcatttagtt gtttgtcaag aaaaaagtac
    38221 gaaaatgacg aaaaaagtca aaaaaaatta aaaataggtc gcaagtcgga tgttt
//
LOCUS       DAVFJR010000018        35708 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVFJR010000018 DAVFJR010000000
VERSION     DAVFJR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.019"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..96
                     /locus_tag="VU722_001120"
     CDS             <1..96
                     /locus_tag="VU722_001120"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Catalyzes the transfer of the phosphoribosyl moiety
                     from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the
                     6-oxo-guanine and -xanthine; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU1772107.1"
                     /translation="DLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            96..1358
                     /locus_tag="VU722_001121"
     CDS             96..1358
                     /locus_tag="VU722_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU1772108.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(1445..2311)
                     /locus_tag="VU722_001122"
     CDS             complement(1445..2311)
                     /locus_tag="VU722_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HEU1772109.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(2298..3068)
                     /locus_tag="VU722_001123"
     CDS             complement(2298..3068)
                     /locus_tag="VU722_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU1772110.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(3094..3948)
                     /locus_tag="VU722_001124"
     CDS             complement(3094..3948)
                     /locus_tag="VU722_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEU1772111.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDVFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(4105..4509)
                     /locus_tag="VU722_001125"
     CDS             complement(4105..4509)
                     /locus_tag="VU722_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU1772112.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(4579..6060)
                     /locus_tag="VU722_001126"
     CDS             complement(4579..6060)
                     /locus_tag="VU722_001126"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU1772113.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            complement(6079..7257)
                     /locus_tag="VU722_001127"
     CDS             complement(6079..7257)
                     /locus_tag="VU722_001127"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU1772114.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPATISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDALVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            7421..8428
                     /gene="galR"
                     /locus_tag="VU722_001128"
     CDS             7421..8428
                     /gene="galR"
                     /locus_tag="VU722_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU1772115.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(8474..9466)
                     /locus_tag="VU722_001129"
     CDS             complement(8474..9466)
                     /locus_tag="VU722_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU1772116.1"
                     /translation="MDLRPQIIEADDVIIRVVRACVCGSDLWRYRNPETKAGHKNSGH
                     EAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGSCDNHIGNNLGGDFQA
                     EYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHAARVANVQKGDKVVVI
                     GDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVVAERGQEGITKVREIL
                     GGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRALGSTFMQNISVAGGAA
                     SATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDERKTIKSMIVIE"
     gene            complement(9501..9854)
                     /locus_tag="VU722_001130"
     CDS             complement(9501..9854)
                     /locus_tag="VU722_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU1772117.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(10098..10988)
                     /locus_tag="VU722_001131"
     CDS             complement(10098..10988)
                     /locus_tag="VU722_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU1772118.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLVDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINMLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            11121..11657
                     /locus_tag="VU722_001132"
                     /pseudo
     CDS             11121..11657
                     /locus_tag="VU722_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            complement(11824..12630)
                     /locus_tag="VU722_001133"
     CDS             complement(11824..12630)
                     /locus_tag="VU722_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU1772119.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKTIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(12975..14495)
                     /locus_tag="VU722_001134"
     CDS             complement(12975..14495)
                     /locus_tag="VU722_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU1772120.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(14488..15216)
                     /locus_tag="VU722_001135"
     CDS             complement(14488..15216)
                     /locus_tag="VU722_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772121.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(15231..15995)
                     /locus_tag="VU722_001136"
     CDS             complement(15231..15995)
                     /locus_tag="VU722_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU1772122.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(15999..16442)
                     /locus_tag="VU722_001137"
     CDS             complement(15999..16442)
                     /locus_tag="VU722_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1772123.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(17124..17420)
                     /locus_tag="VU722_001138"
     CDS             complement(17124..17420)
                     /locus_tag="VU722_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU1772124.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(17442..18506)
                     /gene="pepA"
                     /locus_tag="VU722_001139"
     CDS             complement(17442..18506)
                     /gene="pepA"
                     /locus_tag="VU722_001139"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU1772125.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKLDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            18907..19608
                     /gene="galE"
                     /locus_tag="VU722_001140"
     CDS             18907..19608
                     /gene="galE"
                     /locus_tag="VU722_001140"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU1772126.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNASGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            20031..20990
                     /locus_tag="VU722_001141"
     CDS             20031..20990
                     /locus_tag="VU722_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772127.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWVLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            20980..21936
                     /locus_tag="VU722_001142"
     CDS             20980..21936
                     /locus_tag="VU722_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU1772128.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLNCLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLNILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            21933..22685
                     /locus_tag="VU722_001143"
     CDS             21933..22685
                     /locus_tag="VU722_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1772129.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            22781..23746
                     /locus_tag="VU722_001144"
     CDS             22781..23746
                     /locus_tag="VU722_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772130.1"
                     /translation="MKTSLKLYFIALVASFLLLLGACSTNSSTSQTEPSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(23971..24213)
                     /gene="yidD"
                     /locus_tag="VU722_001145"
     CDS             complement(23971..24213)
                     /gene="yidD"
                     /locus_tag="VU722_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU1772131.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMSLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(24213..24935)
                     /locus_tag="VU722_001146"
     CDS             complement(24213..24935)
                     /locus_tag="VU722_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU1772132.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(24922..25491)
                     /locus_tag="VU722_001147"
     CDS             complement(24922..25491)
                     /locus_tag="VU722_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU1772133.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(25510..26238)
                     /locus_tag="VU722_001148"
     CDS             complement(25510..26238)
                     /locus_tag="VU722_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU1772134.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(26238..26978)
                     /gene="xerD"
                     /locus_tag="VU722_001149"
     CDS             complement(26238..26978)
                     /gene="xerD"
                     /locus_tag="VU722_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU1772135.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(26969..27430)
                     /locus_tag="VU722_001150"
     CDS             complement(26969..27430)
                     /locus_tag="VU722_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1772136.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(27427..27948)
                     /locus_tag="VU722_001151"
     CDS             complement(27427..27948)
                     /locus_tag="VU722_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU1772137.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(27924..28895)
                     /locus_tag="VU722_001152"
     CDS             complement(27924..28895)
                     /locus_tag="VU722_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU1772138.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(28892..29686)
                     /gene="racE"
                     /locus_tag="VU722_001153"
     CDS             complement(28892..29686)
                     /gene="racE"
                     /locus_tag="VU722_001153"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU1772139.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(29893..30141)
                     /locus_tag="VU722_001154"
     CDS             complement(29893..30141)
                     /locus_tag="VU722_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU1772140.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(30397..32022)
                     /gene="treC"
                     /locus_tag="VU722_001155"
     CDS             complement(30397..32022)
                     /gene="treC"
                     /locus_tag="VU722_001155"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU1772141.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(32200..34167)
                     /gene="treP"
                     /locus_tag="VU722_001156"
     CDS             complement(32200..34167)
                     /gene="treP"
                     /locus_tag="VU722_001156"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU1772142.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTINRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            34352..35062
                     /gene="treR"
                     /locus_tag="VU722_001157"
     CDS             34352..35062
                     /gene="treR"
                     /locus_tag="VU722_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU1772143.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVGRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            35217..>35708
                     /locus_tag="VU722_001158"
     CDS             35217..>35708
                     /locus_tag="VU722_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772144.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKMSMTDIAHQLSISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKG"
BASE COUNT        10441 a         8302 c         6575 g        10390 t
ORIGIN      
        1 gatttgcttg aaaaagcagg ctaccctgtc ctatcacttg ctcgtttgga tcgttttgaa
       61 aatggtcagg tcgtatttaa ggaggcagat ctctaatgca aactcaagaa aaacactcgc
      121 aagcagccgt tcttggcttg cagcacttac tagccatgta ctcaggatct atcctggttc
      181 ccatcatgat tgcgacagcc cttggctatt cagctgagca gttgacctac ctgatttcta
      241 cagatatctt catgtgtggg gtggcaacct tcctccaact ccaactcaac aaatactttg
      301 ggattggact cccagtcgtt cttggagttg cattccagtc ggtcgctccc ttgattatga
      361 ttgggcaaag ccatggtagt ggcgctatgt ttggtgccct tatcgcatct gggatttacg
      421 tggttcttgt ttcaggcatc ttctcaaaag tagccaatct cttcccatct atcgtaacag
      481 gatctgttat taccacgatt ggtttaacct tgatccctgt cgctattgga aatatgggaa
      541 ataacgttcc agagccaact ggtcaaagtc tcttgcttgc agctattact gttctgatta
      601 tcctcttgat caacatcttt accaaaggat ttatcaagtc tatctctatt ttgattggtc
      661 tggttgttgg aactgccatt gctgctacta tgggcttggt ggacttctct cctgttgcgg
      721 tagctccact tgtccatgtc ccaactccac tctactttgg gatgccaacc tttgaaatct
      781 catctattgt catgatgtgt atcatcgcaa cggtgtctat ggttgagtca actggtgttt
      841 atctggcctt gtctgatatc acaaaggatc caatcgacag cacgcgcctt cgcaacggtt
      901 accgcgcaga aggtttggcc gtacttctcg gaggaatctt taacaccttc ccttacaccg
      961 gattttcaca aaacgttggt ttggttaaat tgtcaggcat caaaaaacgc ctgccaatct
     1021 actacgcagc tggtttcctg gttctccttg gactgcttcc taagtttggt gcccttgccc
     1081 aaatcattcc aagctccgtc ctcggcggtg ccatgctggt gatgtttggt tttgtatcta
     1141 ttcaagggat gcaaatcctc gcccgagttg actttgctaa caatgaacac aacttcctta
     1201 tcgcagctgt ttcaatcgct gcaggtgtcg gtctcaacaa cagtaatctc tttgtcagca
     1261 tgccgacagc cttccaaatg ttcttctcaa acggaatcgt cgtagccagc ctactcgcca
     1321 ttgtcctcaa tgccgtatta aatcataaaa agaaataaga aaaagaggtg cgagcctctt
     1381 ttttgtttat cacaaattga ttataaatac aatcaatccc aattcccatc taattgaatt
     1441 ggacctattt caaattcttt aaaatattat gttccaaatc gttaatatta tataagaatg
     1501 gtaaaatatc aaatgtttct cgtaaattat tcttagcctt ataccaacct tgtccatcag
     1561 taatccacat aaactcaaca ttaggaatag ctttagtttc ttcagcaatc attttgtaag
     1621 atctagccgt ctcatttaat tttgaaccac ttcctgaata aaaattaacc tcaatcagat
     1681 aaagcacttg ttcatttttt atgacaaaat caaaacgttt cacagtattc ccatcattcg
     1741 taatagcaga taaatcgaca gaaaaaattt cctctatttc attttgttca atctctttaa
     1801 ataaattctc tcctaaaata tacccttcag cttcaagata gctttgaaca atattttcca
     1861 tcgcatctcc agtccgattt ttgcgcccat tagtatccat accaacctca acacctgtaa
     1921 cgtagtcaac taaatttgat actaaatgat tttgcaataa atcaaatata cctgattttt
     1981 ccaaaaacat agtatattct tcaatactat agtttcgttt actaaaatca aaatagaaat
     2041 cttttatcgg atccttaaca ataatcgtat ctctcaaacg tttagcaata agtagaggca
     2101 caactttcaa aatttctgga taattttgat ataagtctaa aaaatcctct tgtatatttt
     2161 tactaccaat aagactattc ataatattta gagcaacttt tatactagat acatttttat
     2221 aaaccttagg aaaatctgta taataagtcc agtcagctac tgtgtcggtc atcgttgaca
     2281 accactcatc aaaatttcta gtttgtttca ttttctgcct ccaacctctt ccttgcaatt
     2341 tttaaatatt ctttttcagc atcgatacct ataaatcttc tacctaaccg cttcgcaaca
     2401 acacccgtag tgccactacc aacaaatggg tctagaatat agtcaccctc tttagtagag
     2461 gctaaaataa tacgttctaa caaatactct ggtttttgag ttggatgttt cccagcccat
     2521 ttttcaactt tctttgttaa agaaccggtc cagacatctt tcatttgttt tccatcattc
     2581 aattctttca ttaaatcata attgtagtaa tgacgagctt ttttatcatt ttttctggcc
     2641 cataaaatgg tttcagtaga atgggtaaaa taacgacaag ataaattggg ggcagggttt
     2701 gttttctgcc aagtaatatt attcagaatt ttaaaacctt cttgttctaa tgccattcca
     2761 actgagtata tgttgtgcaa actacctgaa atccataccg tcccattagg cttcagaact
     2821 tcttttgcta ggcgaatcca tttacgatta aactcatgtt tttcttcgaa tgaagaaatt
     2881 ttatcccaat ctcctttatc aacagaaact acttgtcccc cagaattaga tattccacca
     2941 ttacttaaaa aataaggtgg atcagcaaaa atcatatcca tactttctgg tttcattttt
     3001 gataagaact tgaacgtatc tgaatgaaca agaatcatct tatttttatt gtagtatggt
     3061 tttgtcataa gaacacctcc atacttatat tcgttatttt tcataatttg tgactataat
     3121 ttcagaaatt tttcctcgac ttgaagattt tgctccatta gttcgggtag cttcaacata
     3181 atgtatatta aaatccttat acaactcctc tactaaagca ctagaagaat ttgataacat
     3241 aacataagct cctgtatcac ttaatctctt aaagacatct cttaatctta cttgatctgc
     3301 aaaagagaat ccctcatgag tataagacgt aaatgcactc gtctcagaca atggaatata
     3361 tggagggtca aaatacacaa aatctcctgt tcgaacatct acaattgcct tttcaaaatc
     3421 tcccacttta atttctagtt gattgttatt tagataaact gaaatagcag atatcaattc
     3481 ctcatcaaca attttaggat tcttataacg tccatatgga acattaaatt ggttcttaga
     3541 attcacacga tatagaccat taaagttcac tctcaacata tatagaatac gtgcagctct
     3601 ttgtacttcg gacatcatat ctattctttc atcacgatct gcagaacgta aatctaaata
     3661 atattctttt gaattatatt cctgatgaac tttcaaaatt tcaatcaatt cttgaggatt
     3721 gtccttaatt tgttgatagc aatttattag ttcagcgtta aaatcattaa taactgcatc
     3781 tttaggagcc aaatcaaaaa ataaagctcc acctccaaca aaaggttcga aatacctgtt
     3841 ataggtttta ggcattaatt ctctaataac aggcaataat tgtcttttac cacctgtcca
     3901 tttcgtgaac ggttgtaaag taactttctt tatttctttt atcttcatgc ttttaattat
     3961 accatagaaa ttaaaacaca actcttgtat tttctaccac attactaaat tttctatttt
     4021 agaattaaat catatcaata tcaaaaaatg agtaaggcaa atcttataaa ttccaaaatt
     4081 cacctcactc tattaaatta ctctttatat ccttacctgt ctttcttctg accgctggcc
     4141 tgtgacaaac atggtaaagg ttgctttaca gacatttctg ccctcttgat tggtgatatc
     4201 cacatccatc acacaggttg tacggccttg atggacacat tctcctttaa tggtcaatac
     4261 atcgtcgagt tttcctgcct taaggtagtt gatagaggat tggagtgtca ccccatcaag
     4321 tcccagcgag ataaccacca aaccactgat ttggtcacat agcgtgaata gatagccacc
     4381 atgggcattg ccatagtagt tgagcgacga gttcactact ttggtcgtca ccacaacgtg
     4441 accatctctc attttttcaa tttcgtaatt ttcaaaggca gatatagcgt caaaatgaaa
     4501 gtctttcatc gtttcctcct gatatttcaa acgacactat gatactactt tttataggac
     4561 tgtgcaagga gaaagctcct agtctagtga aattccgaca tgttccacaa agcgcataaa
     4621 ggctgtctgc ccttgttctg tctgcttgta gactcctgca tcctcaagta cacgcacaaa
     4681 gatagcaccc acagagtcct tgacgattgc aagggctttt tctttatccg ttaggtctgg
     4741 atgttgggat ttgagttggt ctgcccactc ctgatgataa tcggcaactg taacagcttc
     4801 tcctacaaga tagctagcga cttgctccac ttcttctttc agacgtggtg gcaagattgc
     4861 caagcccatg acctcaatca agccgatatt ttccttcttg atatgttgga catccttgtg
     4921 gggatgatag atgccatcag gatgctctgc tgaagtctga ttgtctcgca agaccaagtc
     4981 caactcaaac tgtccatcac gcttacgcgc tattggtgtg atggtgtgat gcggtgtccc
     5041 gtctgtctct gctaaaatct gcacactaga atctgaatac tgacgccatt cctggaaaat
     5101 cttatcagct aagttaatca aatcctcttt ggaatccgaa gtcaagcgta ggacagacat
     5161 tggccacttg ataattccag ccttgacctg ctcaaaacca gcaaatcgga aggtcttttg
     5221 caagggagcc aattccatag gaaatacgtg acggcctccc tgataatgat catgagttag
     5281 aatagagccc cccacaatcg gcaggtcggc attagatcca gcaaaatatc ctggaaactg
     5341 ctctacgata gccaacagac gttcaaaact ctgacgacta atggccatgg gacgatgctg
     5401 gccatctaaa aagatacaat gctcattaaa gtaagcatag ggcgaatact ggaaccccca
     5461 ttcctgacca accatttcaa aacggataat ccggtggttg ctgcgagctg ggtggttgac
     5521 ccgaccatgg taaccctcat tctctaaaca aagttgacac tgaggataat tactagcttg
     5581 caccaacttg gctaccgcaa tctctttcgg atccttttca ggcttagaga gattgatggt
     5641 aatttcaagt tctccataat cagatggaac acgataagcg atatttttag caatggcctt
     5701 gagtttgatg tagtcatttt tccgactgag ttgataaaaa tcctctatcg cttgctcagg
     5761 agagtaggca taggcttccc agaagtcacg attgacctga ctcggacaag gagtcaccaa
     5821 gtccatcagt tcagtaccaa ggatttcacg cgcagtctga ctatcctcaa tcgtctctaa
     5881 tcgaacggct tcctcaacta gctggtcctt gaggtcaatc aatttatcca gattggtctc
     5941 aacttccaaa acaccttctc ccactcgtgc caaaacacgg tttgtcaggt agattcgatc
     6001 catttcctca aatgaacttt cagaaatgac atgtgttaca aatttatcta ctaaggtcac
     6061 tatagagcct ccttttgact agtcaaggac gcgagtgcca cctgcaactt cagcgatata
     6121 gaagcttgga gcgtatccaa ctacttcctc gtagtgtttg cctacagctt ccttaaaggc
     6181 ctcaacagta tctttttgaa ccaaggcaat ggcacagcca ccaaaaccag cccctgtcat
     6241 acgagcaccg agaactcctt cttgtgccca agctgtgtga acaagagcat ccaattccaa
     6301 accagttact tcataatcac gctccagaga aacgtgtgac gcattcatca aacgaccaaa
     6361 tgtttccaaa tcacctgctt gaagggctgc ttgagcttta agggtacgtt ggttttcaag
     6421 cacagcatgg cgagcacgtt tcaaacgatt ttcatcttta atcaaatagc tatattggtc
     6481 aacggcccac tcgtccaatt cacccagggt ctgaatatcc aaggcaactt gcaattcttc
     6541 cactgctttt tcacactcag cacgacgttc attgtattta gaatccgcca attcacggcg
     6601 tttgttggtg ttcatgataa caacgacatt gtccttcaaa tcaagtggca ccaaatcata
     6661 ctctaaggtg ttggtatcaa ggtaaatagc acgttgatca gcccccatac caatagcaaa
     6721 ctggtccatg ataccagagt tgactccgat aaagttattt tctgtttgtt ttccgatttt
     6781 aaccaaatcc aaacgctcta attttaaatc aaagagatgc tctgccacta cccctgtcaa
     6841 gagctccaag gatgctgaag aagacaaacc agcaccattt gggatattcc cataaacata
     6901 aaaatcaaaa cctttgtcaa tcacgtgccc agcttcttgc aagaaatgaa ggacaccttt
     6961 tggataattg gtccagttgt gctctttttc aaacttgagg tcagcgagag gcacttcgat
     7021 aatgcccttg tcctcaaagt tagctgagta gaaacgcaaa acttggtcgt cacgcttacg
     7081 agctgcaccg taagttccca aggaaatagt agcaggaaaa acgtgcccac cgttgtagtc
     7141 tgtgtgttca ccaatcaaat tgatacgacc tggtgaaaag aaagtttggt ctgcttcttg
     7201 accaaaaaca gcaagaaagt ctttgcgaag agtttcagca gtaagatgtt gtgtcatatg
     7261 atttctcctt tgactgtccg ttaagccacc ttaacgtgta atcgttttct tctattgtat
     7321 ccaaggaatt tcccaaggtc aatccttttt actaaaattt tagtaaaata tcagtaaaaa
     7381 gaagaaaaat atgatatact aacctaatca aggaggattt atggctacct taaaagacat
     7441 tgcacagcta gcctctgtct ctatcgcgac cgtatcccgt gtcctcaacc gcgaccagag
     7501 cctatctgtt acagaagaaa ccagacaccg tattttaacc gttgctgaag agctgggcta
     7561 caccaagcac ctcaagacag gcgagtccca taaacccaag caaaagattg ccattattca
     7621 atgggtcagc gaacaagggg agctagacga cctctactac taccagattc gcctaggaat
     7681 agaaaaaaga gcccaagagt tggactacga tatcttgcgc tactttaatg accacccttt
     7741 taccctaagc gaggaagtga ttgggattct ctgcatcgga aagtttagtc gagctcagat
     7801 ttctgccttt gaagaatacc aaaagcctct tgtatttcta gacagcgata cactttccct
     7861 gggacatacc tgtattatca cggattttta cactgctatg aaacaggttg tcgattattt
     7921 cctcagccaa ggaatggacc gtatcgggat tctaacaggc cttgaagaaa caactgacca
     7981 agaagaaatc attgaggata agcggctgga aaatttcaga aactacagtc aagcaaaagg
     8041 aatctatcat gatgaactga tctttcaagg aaactttact gcccagtctg gctatgactt
     8101 gatgaaggaa gccattcaga acttgggaga ccaactccca ccagcatttt tcgcagccag
     8161 cgatagttta gccatcggtg cccttcgtgc gctccaagaa gctggaatca gcctaccaga
     8221 ccgtgtcagc ctcatttcct ttaacgacac cagcctgacc aagcaggttt atcctcccct
     8281 ctccagcatc acagtttata ctgaagaaat ggggcgagca ggtatggata ttcttaacaa
     8341 ggaagtcctc cacggtcgga aaatccctag cctgaccatg ctgggaacca gactgacatt
     8401 aagagaaagt accctaaatc aagaatagga taacataaaa aacgaataga gttctaaaac
     8461 tcctattcgt tttttattcg attacaatca tagacttaat tgtcttacgt tcatccatat
     8521 ctttataggc ttggtcgata tcttccagtt tataacttga agtaaagacg cgacctggat
     8581 tgatatcacc atcaaggacg gcttttagta aaaattgctt atcgtatgtt gtagcagaag
     8641 ctgccccacc tgctacagag atattttgca taaatgtcga accaagagca cgattattat
     8701 agtgtgggac tcctacaaag cccatacgcc ctccattatg aagaacacct agcgcctgtt
     8761 ctatagcagc ctccgtacca acacattcaa gtgctgcatc tgctcctcca ccgaggattt
     8821 cacgcacctt ggtaattcct tcttgaccac gttctgcaac aacagctgtc gcacctgact
     8881 ccatagccat cttttgacgg tcttcatgac ggctcataag gataatttgt gatgctccac
     8941 gcatcttagc cgcgatgaca gcacattgac caacagcccc atcaccgata acaacaacct
     9001 tgtccccttt ttgaacattt gcaacacgcg ccgcatgata gcctgtcggc atgacatctg
     9061 caagagtcaa aagggacttg agcatccctt ctgtatagtc agaaggttga ccagggattt
     9121 taaccagcgc ccagtttgca tagtggaagc gaatatattc tgcctgaaaa tcacccccca
     9181 aattattgcc aatatgattg tcgcaagaac cgtcaaatcc agcaagacag gcatcacact
     9241 caccacatcc atgtgtaaaa gggacaatca caaaatcacc tggtttcacc gtcgtaatgg
     9301 cttccccagc ttcttcaaca atcccaatcg cttcgtgtcc actatttttg tgtccagctt
     9361 tcgtttctgg attacggtac ctccataaat ctgaaccaca aacgcacgca cgaaccacac
     9421 gaataatcac atcatccgct tctattattt gcggacgcaa gtccaacctg acctgccttt
     9481 gtatatactg ctgatttcat ttaaaatttt ccttccttat aaagtttaat tttgagattt
     9541 aaacgattta aagctgtctg tagctgagac aagcgctcct ctaatttttg cttttcctct
     9601 tctaaaatac caagcctctc ctctctcgtt tcatctccct tttggtagag cgacatatag
     9661 tcaactaaac tatctacaga gacacccgcc gaacgaaaac acttaataaa ttccagcgct
     9721 tcgatatcct gatcttgaaa atcacgaatc ccagtagcag tacgagtaat cggtggcaca
     9781 agaccaaccc gttcataata ccgaatcgta tccgctgaaa ttcccaacaa atcactggca
     9841 gatttaatat tcacacgcta acctcctctc atttcattca ctgaattcac gctattctaa
     9901 ctcacttatc ttattatata actttgagtt gactccaagt caagcatttt gtatctaatc
     9961 gaaaaatttt tatcattaac aatcatatat ctggagttta tacaatgctc ttctcttacc
    10021 aatttttgaa atatttaaat aataaagaaa ttactctatt ccaaataaga tagtacccaa
    10081 gtatttttca cttttttcta atgttgatgc tcataactcc gttccaagtc acacaccttt
    10141 cgcttatggg tttggtgagt ttctaggtca gcatcaattt caatggtaat attttgaaaa
    10201 ccacaatctt ttaggaaaat tcgaatagac tctttacaag tttccatatg ttccatttct
    10261 tttagacaaa catggacaat ggcatttttt tccaaagcat ccatagtcca gagattaagc
    10321 tgattaaggc tggccacatt gtccaatcgc tccaggccac tctttacttg cttgatatca
    10381 agaccttctg gcacagcatc caagaaaatc ttgagtgtag accaaaaacg tggaagggct
    10441 tttgaaagaa taaagaaaga aatgacaagg gacaaaagag gatctaggat ataccagtcc
    10501 gtaaatcgaa gaacaatcgc catcaggata acagctaccc accctagcgt atcttccaga
    10561 aaatgcagac tcagaataga ctcattcttt gtctttccct taccaaccac cagactcgct
    10621 aacatattga tagtaatcgc aataattcct aaccagagaa tcccctcatc attgactggt
    10681 tgcggatgca aaatcttcgt gacattttcc aaaatgacta gaacagagcc cgttacgaga
    10741 atcacagctg ttaccaaggc tcctagcagg ctaaaccgct tatagcccaa ggtgtactga
    10801 ttgtcttctt cacgattgga gattgtttct aaaaaagctg atattccaat tgcaatcgca
    10861 tctaccaagt catgcacaga gtcagcaaga acagcgctag aaccaaatat tccacctgca
    10921 ataaactcaa caatggcata agtcaaattt aagaaaaaag ccacccaaac agcatatttt
    10981 gccttcatat ttctcattcc tttgttataa tagatttatg aacaccttgt tcattatcat
    11041 tatccactaa aactcaaaga aaggatagaa gcaaaacgtc agctttattc agttctgaac
    11101 aatttgcctt aagtgtccat atgactaaca ttgaccgccg tatcagcaaa accaaaaaag
    11161 ccatctatca agcttttata caacttttga atgctaaggg ctacgaggcc actactgttc
    11221 aggatatcat tgatctcgca gatgtgggac gatccacctt ttactgtcac tatgagagta
    11281 aggagcttct tctggaccag ctctgccgct acctcttcca tcatcttttt gaaagagagc
    11341 aagccatttc aaccgaggac tacctcgccc acctctttct ccattttcat aaaaaccaag
    11401 accatatcac cagtctgcta ttttccaaaa atgactactt cctccgtcaa ctctagagag
    11461 agcttgagca ccacgtctat tccgtgctag ctgataattt aaaagaagcc caccctaatc
    11521 tgcctacttc ttacctccaa cacttggtca tgtccaactt tatcgagaca ttgacctggt
    11581 ggctcaaaaa aggtcaagat ttcacagacc aggaagttgt ccaattttat ctagaccttc
    11641 tcattcctaa aaattgaata tagagtaaag cttcagttgt cttatttcta ggttactgag
    11701 ttttttatct tttcaacaac aaaagaggac ccgccgatcc tctttttcat actataaatc
    11761 cttgattatc aactatatct gttttaatcg aaatctcaaa acagcacttt caaacatctt
    11821 ttcctagtta agtaaatcag tattctgctt agctgccttg ctccattgat accaaccaac
    11881 tagactgtta atgagataaa ttagatattt cccttgaatt tgcaggcttt ctccccacca
    11941 gagatagatt gaaaagacat tggtagccgc ccagaatatc cactgttcac ggtaaacagc
    12001 tgtcatgagg atttgcccta ccccattggt tgcatctgtg attgaatcac gatagggacg
    12061 attggcacca atagactgat aaatgaagcc aaaggccaac caccaaagca cactaatgga
    12121 aagatacttt gtccagccct tgccgtccag tttacgcgcg acaaactcct gcttttcctt
    12181 cttaaactgt gcctgataaa tccaaactag aagtccaatt ggctgcatga ctgtgaagta
    12241 aagtgtcgtc agcacctcac cataaaagcc tttctgtagg gccaaaataa ggtaaataac
    12301 agagttaatc aagccaaaaa gataattact tgctcgacct tccgatacaa agattacaca
    12361 gataatccct gtcaagctac aaatcatccc aatccagtca acaatacgat gttcgtaaac
    12421 caactccagc cagagaggaa aacttcctaa aaccagcaaa taaatccact gggcaaaact
    12481 acgatgggca aagaggtcat cccagatagt cttcatagtt cctgaaaatc ctaaatcagc
    12541 catagccgca accatacgac ggtaaccacc tgacatttca cctagggttg ttttgatatt
    12601 ttcaattttc ttttgcaaat aagtatgcat catttctcct tttgttttta aagagccgtg
    12661 tctggataga ctttcggacg caacgctcta ttagataatg aactgcctat acacaagatt
    12721 tctaacctta gtcgacatga gctgaaaccc cttatttgtt aagtagttca caaaatatta
    12781 tacatctatt ttatgaatag tcaagtgtct ttacagtaaa attttagaaa atcatgaaaa
    12841 ttttctcttt ctttccattt taagtgacat tcagtcattc tcacatcaaa aaagcccaga
    12901 cgaaattgtc tgagcattct tttatctagt cgtttaagga agttgagttc agtatgttta
    12961 aagtctctgt cccatcattt cttcaacaaa ccttgttctt ggagaaactc cttggctact
    13021 tgctctgctg acttgccttc aacaccgact tggtagttga gctggctcat ctggctttct
    13081 gtaatcttac cagccaatgt attaagaact ctttccaact ctgggtgttt cttgagaaga
    13141 gcttctttca tgagtggagc cccttgataa ggtgggaaga gttgcttgtc atcttccaag
    13201 acctgtaaat cataacgctc caattccgca tcagtcgaat aggcgtccgt aatttgaata
    13261 tcacctgact gaatagcctg atagcgaagg gctggctcca tggtcgctac attgagattg
    13321 agaccataca ttgattgcaa gcccttattt ccatcttcac ggtcgttaaa ctcgagtgta
    13381 aaacctgcct tcaactgccc ttccactttt ttcaagtctg aaatggtctt caagccatat
    13441 tcttgagcaa tctttttcgg aacagctaca gcataggtgt tttgataaga catgggtttg
    13501 agataggcta gatgatcctg cttagcaatg ccatcacgcg ccacctgata aacctgttct
    13561 ggttcatgac tcaccttggg tgatggttga agcaaacttt cagtcaccgt accagtaaat
    13621 tcaggataga tgtcaatatc gccttttttc agagcttcat aaaggaagct tgtcttccca
    13681 aaattcggtt taacagtcgc agtcatgctg gtattttctt caatcagcaa cttatacata
    13741 ttggccaaaa tttctggttc tggacctatt ttcccagcaa taaccaagtt ttccttctct
    13801 ttttgaacca aaagagctgg actataagac agacccagta ataaagccac caaggcaaaa
    13861 cctgagaaaa tcgtccgtaa ttttgctttt tccattactt ttagtaggaa gttaaaggca
    13921 atagcaagca ctgcagaaga aagtgcccca atcaaaatca aactggcatt attacggtca
    13981 attcccaaca ggataaagga acccagtccc cctgctccaa tcaaggccgc caaggttgcc
    14041 gtaccgataa tcaaaacagc tgccgtccga atcccagaca tgataacagg catggcgagt
    14101 ggaatttcaa atttcttgag acgttcccat ctggtcatcc caaaggcaat cccagcctct
    14161 tgcaggttcg gatcaattcc cttcagccca gtgatagtat tttgcaaaat agggaaaatc
    14221 gcataaatca ctagagctgt caaagccggc aaggtcccaa ttcccatcaa agggataaag
    14281 agccccaaca aggccagaga cgggatggtc tggaaaatac ctgcaatctg caagacccag
    14341 tcggccagct tctcatgata gcgaagaaaa acagccaagg gaatcgcaag caaaatagct
    14401 agtaacaagg tcaaaagtga caactgcaaa tgttgagata gagctgtcaa ccaatcacta
    14461 aaacgatcct gaaaagttgc aattaaatta gtcatgaaca ctacctccaa acaagtctgc
    14521 tacaaagtct gttgcaggca cttttaaaat tgtctcggga ttcgctacct ggcgaatttc
    14581 tccatcctgc aagacagcaa tacggtccgc caacttcaag gcttcatccg tatcatgggt
    14641 tacaaaaatc gttgtcatcc caaactcttt atgcaattct tttgtcagaa cctgcaactg
    14701 ttttctcgaa atagcatcca aggccgaaaa gggttcatcc atgaggaaaa tcttgggctg
    14761 accaatcata gctcggacaa taccgacccg ttgctgttct ccaccagata attcactagg
    14821 taagcgatgc ccatactcgg ctactggtaa accaacctta gccaaaagct cttctgtttt
    14881 cttcgtaatt tcttccttgc tccacccctt catttcagga atgagagcaa tattttccgc
    14941 aactgttaga tttggaaaaa gagcaatagc ctgtaaaaca taaccagtag aaagacgaag
    15001 ttcacgctca tcatagtctt tgatgcgctt cccatccata taaatatttc catcagttgg
    15061 ttccaaaaga cggttaatca tcttgagcat ggtcgtctta cctgacccag aaggccctac
    15121 taaaaccata aattccccat cctcaatctg taagttgaca tctctcaaga catccttttc
    15181 tgtgtagcgc agtgctacat ttttgtattc aatcattctt tgtcctcaat ttaaaacttc
    15241 cctcgattag tcaagtcttc taccttaggc atgacttcct tattatccca atgctccaca
    15301 attttcccgt tctctaaacg gaagatatcg tactgggcat aagcaacgcc atcaatctga
    15361 gtctgaccat agctaaccac atagtttcct tgtcctaaga gttggaaaac aaagtcaaaa
    15421 gtgacactat attcagccac atagttttta taagcagcac ttccttgtcc aatctcatga
    15481 ttatgctgaa tcaaatcgtc tgccacataa tcactccact gctctagctc cccattttgg
    15541 aaaatttctg tcaagaaacg gcgaaccagc tttttatttt ctgctttctt atccaaatcc
    15601 ttgatttcaa aatctccaaa aatttgatct agttggtcat tttcaggtgt tcgatagtag
    15661 tcaatgacat cccaatgctc aacaatacaa ccattctcat ccgcacggaa agtatccgtc
    15721 gtcacccatt gagcttctcc accattcaga tattgatgaa catgaacaaa gaccagattg
    15781 ccatcctcaa tggtgcggac aatcttaatc tgacgctctg gatgacgctc aaagaaatct
    15841 gcaaagaagg ctgcaaatcc ttctttcccg tcaggaacac ctgtcgaatg ttggatatag
    15901 gtatccccta cagactgggc ttgagcctca gcaactcgtc cgtcttgaat ggcatggatg
    15961 tataggttgt gagcattttt cacttgttgt gacatattct aaacctcatt tcccttctct
    16021 ttcagattcg ccaaaattct ttcttgaaaa ccttcaaatt ggtgaatttc ttcctctgaa
    16081 aatcctttgt aaaagatagt atccaatttc tgactgacac gatgccccac ttctttctgg
    16141 gacttgccta actccgttaa aactaaatac ttcttacgct tgtcttttcc acacggacta
    16201 acaattacaa gcttttgttc ctctagcttt tttatcatag tcgtcagcgt attattcgca
    16261 agcccagtcg caagcgcgat atctgtcgca gttgcgcagc cagtttcact attccataaa
    16321 accgctaaaa tcttgccctg ttcaccccta taaagagcct caggatcttg actcagtaac
    16381 ttttgaaaaa tccgcccatt caacaaacga atatgatggg ctagcaaatg actatctttc
    16441 ataacacctc caatttattt cgatgtcgaa atgaataaaa taattgtaac actcatcgtt
    16501 ctaactgtca actatttcga tttggaaata atttttgata attattcaca ccaccatact
    16561 ccggctcaac taacttttaa cgagagtttc taaattcctt cgtcctccag tctacaaaag
    16621 ccttccatcc gtactatcct attttttatg aggggacaca tttttcctat cagatcattt
    16681 attttaaaga tagaagtaaa tcataattgc ttccatctgt tcttttatag tatattgaag
    16741 ttggactagg gcactgtatc ttctaaaaca ttgatagaaa gcgatttgaa tttcccaatc
    16801 aatttgttcg tatttatagc attttgaaac tagaatagga cgccatgact gctaaaagat
    16861 ttctataaat tcatttgatt ttcctaatca atttgttcat atcttatttc attccgctat
    16921 aatttcacct taccctatct ttttcgtagc acccttcaaa cagcctatcc cctaccgttt
    16981 gacgattcct cacttcactc cacttccatt acagaagttt cttcactact atggtctcgg
    17041 ctgacttctc atgattcctt gttactacta tttgaacgct cacgagatag gtcttataaa
    17101 aaatgctttg atccacaatg gaatcaaagc attttaaaga gttcctcata cataagcgca
    17161 gaagtcgcag ttcctctgta cttggcttct tctcttttga taaagcgagc caagttgagc
    17221 aactcaggtg ctggatgttt gggatttagg agcaattcac gattgaccag gcctgagaga
    17281 cgaactgcct gcaattgctc atttgtagta ggcagttttt tagtagtctc taggagagca
    17341 gcaactaaat cttcactcaa atcatgtcga gcatgattgt aaagatcttt tataaggctt
    17401 tctaggtttg gttctgccat ccctaccacc tcccttatgg tttaataatg tttaatcaaa
    17461 tcaaccgttg aacgatccaa tttcttcacc aaggcttgta agaaagcttg cgcttctagg
    17521 aagtcatcca ttgcatagag ggtttggtga gaatggatat aacgagcgca gacaccgata
    17581 gttgttgatg ggacaccacc atttttcaga tgagctgcac ctgcatctgt tccgccttta
    17641 ccacagtagt attggtactt gataccagct tcttcagccg ttgtcaaaag gaaatccttc
    17701 atccctggga gaagcaagtg acctggatca tagaaacgaa tcaaggttcc atctccaatc
    17761 ttgccttgac caccgtagac atcacctgct ggtgagcaat caactgcgag gaagacttct
    17821 gggtcaaact tggttgtaga ggtatgagcg ccacgcagac caacttcttc ttggacgtta
    17881 gaacccagat agagttcatt gccgagtttt tgacctgata aagcttcagc tagctcgctt
    17941 accatgagga caccgtagcg gttatcccaa gcttttgaga tgatattttt ttcattggct
    18001 gtcaaaattg cagaactatc tggtacgatg gtatcaccag gacggatgcc aaaactttct
    18061 gcctcagcct tgtccgcaaa accaccatca aaaacgatat cggcaatggc tggcatggtt
    18121 ggtcccccct ttccacgagt caaatgcgga ggaacagaac ctgaaatcac aggaatttca
    18181 tgaccatcac gagtcaagag tttgaaacgt tggctgctaa ccaccatggg gttccagcca
    18241 ccgatttcta cgacacggaa ggtaccatct agcttgattt cgctgaccat aaaaccaact
    18301 tcgtccatat gagaagcgac caagacgcgc ggtgcatcca cagcttctga atgtttgata
    18361 ccaaaaatac cacccaagcc atctgtcacc acttcatcca catgcggtgt caacttttca
    18421 cgaagataag cacggacagg cgcttcatga cctgagactg cagcaagttc tgttacttct
    18481 ttaatttttg aaaataatgt tgtcatttca gttccttctt tctttcatcc attttaccac
    18541 tttttatagg agaaggatag tgggaaggtg gatttctaag ttagtatctt agtcctgctc
    18601 tatcttagaa aaggatagta ttctcttgca tgtagtgcaa aatctagtaa acattccaaa
    18661 attaactcga atatttattt ccaaacaaaa aaacaataca ccatcaaagt tgtttagatt
    18721 tttcatgaaa tttacagaaa atagttgact tccctttctt ctttctttaa atatatagtt
    18781 ggttgagttt ggaatagtac gctgtagctg ctaaaacatt tctagaaatt aatttgactt
    18841 tcctaataga gttgttcata tcttatttca atttactata gtacaaaact agaaaaggaa
    18901 aaaatcatga ccaaaacaat tcttgttaca ggtgggacta gctacattgg ctcccatacc
    18961 gttaaagctc ttttaaatgc tggctatcag gtgcatgtcc tcgataatct ctccacagga
    19021 aatcgagcgg ctgtggatag tcgtgctagc tttaaagaac tggatgttta tgatgctagc
    19081 gccttaaagg cttacttaga agaaaatcag attgatgctg tcctccattg tgcaggtgaa
    19141 attgttgtga gcgaaagtat tgaaaatcca agtaaatact tcactgccaa cgttgctggt
    19201 atgaaccaag ttctcaaagt cttatctgaa gttggcattc aaaaaatcat gttctcttcg
    19261 actgcttctc tctatggaaa taactgtatt gacaagccgg tgactgaaga taccctgctc
    19321 gaccctgtca acccttatgc agagacaaaa ctgatgggcg aacgaatgat ttactggatg
    19381 gccaatcgct acgactggaa atatgttatt ttccgttact ttaatgcttc tggggctgaa
    19441 atggatgctt caaacggtct gcgtgtgaaa aatccaactc acatcattcc aaatatcaac
    19501 aagaccgcat tgggacaaaa tgatagctta aaaatatttg gagatgacta cgatacacgt
    19561 gacggttcat gtattcgaga ttacatttat gtcttggacc ttgcataggc tcatgttaaa
    19621 ggaatgaact acctatttca agaagacagt tcttctcaaa tctttaactt aggaactaaa
    19681 aaaggctata ctatcaaaga aatctttaaa actgctgaag aattactaaa ttaaaaaatc
    19741 ccacacgaga ttgttgctcg acgtgctagt gacccagcca gtgtcctagc agatgcttca
    19801 aaagctaaac aatatcttga ttggacggct agctactccc tcgaagatat tattttatca
    19861 gattaaggta aaaacatttt agaataggat aacaaaggag aaagtcttgt tgctctctcc
    19921 ttgttatatt tattaaattg tcagaaattt tattgacaga ttagaaaaat aatgttacat
    19981 ttatatccgc agatatcttt cgataccaaa tctacatgaa aggacggggt atgaaacttt
    20041 ctcattattt aattggctta cttctactcc tagtctttct ctctattagc attgggacca
    20101 gtgatttttc atggggaaag ctatttgatt tcgaccagca gacctggctc ctttttcaag
    20161 agtcccgtct cccaagaact atcagtattc tcctgactgc ctctagtatg agtatggcag
    20221 gccttctcat gcagactatt acccaaaatc agtttgctgc accgagtaca gttggaacga
    20281 ctgaagccgc caaactggga atggtgctga gcctttttgt ctttccatcg gctagtctga
    20341 cccaaaagat gctcttcgct tttgtttcat ccatcgtatt caccctcttc ttcctagcct
    20401 ttatgaccat ttttactgta aaggaaaggt gggtgttgcc tctgattggg atcatctata
    20461 gcgggattat cggctcagtc acagaagtta tcgcctatcg tttcaatctg gttcagagta
    20521 tgactgcctg gacccagggc tccttctcca tgattcagac ccatcagtat gagtggctct
    20581 tcttaggcct catcatcctg ataaccgttt ggaaattatc ccaaaccttc accatcatga
    20641 atctagggaa agaaaccagc gagagtttgg ggatttccta ctccctactt gaaaaactgg
    20701 ccctctttct ggtggcgcta acgacaagcg tcaccatgat taccgtgggt ggcctaccat
    20761 ttctcggagt tatcgttccc aatcttgttc gcaagcgcta tggagataat ctaagtcaaa
    20821 ccaaactcat ggtcgcactg gttggtgcca atctagttct ggcttgcgat atcctatccc
    20881 gagttctgat taggccctat gagttgtctg tcagtctctt gctaggaatc atcggtagtc
    20941 tcgtctttat cctacttctc tggagagggg gacgaaaaga tgcagactaa aagcaaacat
    21001 accaagctct tctggattct cattattctt gccatcggag cttgtcttct ctacttttgg
    21061 cccatcactc acttgtcagc ctttgcttgg aagttgcgtt cccaaaagat catcgtttat
    21121 ctcttggtag ccatcgcgac tgggatttcg accattagtt ttcaaaccct gacggaaaat
    21181 cgcttcctga cgcctagtat tttgggaatt gaatccttct acgtcctact acaaacccta
    21241 ctactggttt ttgaaagcaa gtttcttcaa cttggcaaat cccctatctt agaattccta
    21301 gtcttacttc ttgtccagtc cctcttcttt ctcgccttac aaggttactt gaagacactg
    21361 atgaagcaag acctggtctt catcctgctg aactgtctag cgctcagaag tctctttcga
    21421 aatatcagca ccttccttca agtcctaatg gatccaaacg aatacgataa actgcaaaat
    21481 agtctttttg cctcctttca acatctcaac acttccatcc tagccatcgg ttctctgaac
    21541 atcctcgctt tgacaatctt tttctttcga aaagcagtcg ttctagatgt cttgcacctg
    21601 caaagagaaa cggctcagat attgggactc gatgttgaaa aagaacagaa agagctcctc
    21661 tggggaatcg tgcttttgac ctcaacggcc actgccttgg taggacctat ggccttcttc
    21721 ggctttatgc tggccaacct cacctacctg attgtcaaag actatcagca caagttactc
    21781 tttatagtgg ccattctggt tggatttatt agcttaacct tggggcaagc cttgattgaa
    21841 cgagtctttg cactggaaat tcgtatcagt atgatcattg agagtgtggg tggcttctta
    21901 ttctttatct tactatatag gaggtctcgt cagtgaaact ggaaaacatt gacaaatcca
    21961 ttcaaaaaca ggatattttg caaggcattt cgcttgaagt cagtcctcaa aaactgacag
    22021 cctttattgg tccaaatggt gctggaaaat cgactctcct ctccatcatg agcagactaa
    22081 ccaagaaaga tcagggagtt ctcagtatca aaggacgtga aatcgagagc tggaattcgc
    22141 aagaactggc ccaagaacta accatcctaa aacagaaaat caattaccaa gccaaattga
    22201 ctgttgaaga actggtcagt tttggacgtt ttccctacag ccgaggtcga cttagatcag
    22261 aagactggga aaaaatccga gaaactctga actatttgga actgaccaac ttaaaagacc
    22321 gctacatcaa tagcctgtca ggggggcaac tccagcgcgt ctttatcgct atggtactgg
    22381 cccaggatac ggactttatc ttgctggacg aaccactcaa caatctcgat atcaagcaaa
    22441 gcgtcagcat gatgcagatt cttcgacgac tggtggagga actcggcaag accattatca
    22501 tcgtcctcca cgatatcaac atggccagtc agtatgcaga tgaaattgtc gccttcaagg
    22561 acggccaggt ctttagcaag ggaagaaccg atcaaatcat gcaggctgac ctgctcagtc
    22621 aactttatga gattcccatc acgctagctg atatcaatga caaaaagatc tgtatctata
    22681 gctagtaaca taaaagctca agttagagaa ccttcagtct cttagtcaat aagattaaga
    22741 gactccctaa atcgttatca cattttaaaa aggagaaatt atgaaaacat cccttaaact
    22801 ttatttcatt gccctagtgg ccagtttctt gctcctactt ggtgcatgta gtacaaactc
    22861 aagcactagt cagacagagc ccagtagctc tgctccaaca gaggtaacca ttaaaagttc
    22921 actggacgag gtcaaacttt ccaaagttcc tgaaaagatt gtgacctttg acctcggcgc
    22981 tgcggatact attcgcgctt taggatttga aaaaaatatc gtcggaatgc ctacaaaaac
    23041 tgttccgact tatctaaaag acctagtggg aactgtcaaa aatgttggtt ctatgaaaga
    23101 acctgattta gaagctatcg ccgcccttga acctgatttg attatcgctt caccacgtac
    23161 acaaaaattc gtagacaaat tcaaagaaat cgccccaacc gttctcttcc aagcaagcaa
    23221 ggacgactac tggacttcta ccaaggctaa tatcgaatcc ttagcaagtg ccttcggcga
    23281 aactggtaca caaaaagcca aggaagaatt ggccaagcta gacaagagca tccaagaagt
    23341 cgctactaaa aatgaaagct ctgacaaaaa agcccttgcg atcctcctta atgaaggaaa
    23401 aatggcagcc tttggtgcca aatctcgttt ctctttcttg taccaaacct tgaaattcaa
    23461 accaactgat acaaaatttg aagactcacg ccacggacaa gaagtcagct ttgaaagtgt
    23521 caaagaaatc aaccctgaca tcctctttgt catcaaccgt acccttgcca tcggtgggga
    23581 caactctagc aacgacggtg tcctagaaaa tgcccttatc gctgaaacac ctgctgctaa
    23641 aaatggtaag attatccaac taacaccaga cctctggtat ctaagcggag gcggacttga
    23701 atcaacaaaa ctcatgattg aagacataca aaaagctttg aaataagcca cttcaaactc
    23761 aatttaatac tcaatgaaaa tcaaagagca aactagaaaa ctagccgcag gttgctcaaa
    23821 acactgtttt gaggttgcag atgaaagctg acgcggtttg aagagatttt cgaagagtat
    23881 aaaattttga cattctaaaa cgcatcctat caagtttatt caaacctgat aggatgcgtt
    23941 tttatcattt tgaaatctat ttaccccacc tcattcccct tcttgatttc gtttaaggga
    24001 aaagtggtct ggaacggggt ccttacctgt tttcgaccag ggatgacaac gtaaaatccg
    24061 agccaagctc atcaataccc ccttaaaacc atgtttttca atagcctgaa tcatgtagtt
    24121 ggaacaagtc agctcaaagc gacaagaggg tggaaagact ggtgagataa aacgttggta
    24181 aaagcgcaca ggcgctatta aaattcgttt cattatttct tagttacagc catggtgtgt
    24241 agttggctga tttctttttt attaagacga cgggattctc ctggacggag tcctgtcaag
    24301 tctaggtgtc cgaaacgagt ccgagacaac ttatctactt ggagaccaac agcttcaaac
    24361 atctttttaa cctgatggtt acgcccttca tggatggtca actgcaccac agagcgattt
    24421 ttgactgggt ccactttgag aatttcataa acagctggct tggttttctt accatcaatc
    24481 tcaagaccac gggtcaaggg gcgaagattg tccttattgg ccacaccttt aacacgcgcg
    24541 acataaacct tgtcaatctc attacgaggg tgaatcatct cgtctgtaaa gtccccatca
    24601 ttggtcaaaa tcaagactcc tgatgtatcc cagtccaaac gacccacagg gtaaatgcgc
    24661 tctttgacat tgggcaagag gtcgacaacc gtcttgcgac ccttgtcatc tgttacactg
    24721 gaaatgacac cgcgtggttt gttaagcaga taatagacct tttcttcgtt gtagataggt
    24781 tgaccttcaa cttcgacctt gtcgcctgac ttgatagtgg ttgctagttc acgcaccact
    24841 tggccgttaa ccgtcaccaa accttgcttg atcagctctt ctgcttttct cctactggcc
    24901 acacctgcgt gggcaatata cttattgatt ctcatcttct tctatccttt caccaaataa
    24961 ttggctttct tgggcttgaa tctcaagctc atcaatcact ggtaattctt ctaaatggtt
    25021 tatccccatg taatctagga aataatccgt agtcacatag aggttggggc gccccaatac
    25081 ttcctttttc ccgtcttcct ttatcaggtc aaaagcttgc aactttgcca aggctccact
    25141 cgagttaacc ccacggatgg catcaatttc tatccgcgta atcggctgtt tgtaggcaat
    25201 aatggacaag gtctcaaggg cagcccgaga caagctctgg ttgataggcg ccttagagta
    25261 ttccttcaaa atctctgcaa attgaggctt ggtcaccaat ctataagcac cacttgtctc
    25321 aatcaaagcc aaactggaat ctgggtcctt ttcatacttc tgggctaatt ttcctaaact
    25381 ctgctggatg cctgtcggtg gcagagagag gagttcagct aactggcgga cccgaatccc
    25441 atcttcaccc gctacaaaca agagcgcttc tatttttgct aaagtactca tctttcctct
    25501 ctatcaagtc tagctttgag gcacttgact ttcttccttc ttttccatga gatagatatc
    25561 tccgaaactc tcctcttgca cgaggatcag ctcctgggtt ttgattaact ctagggttgc
    25621 caaaaagagg gtgatgacct cttggacatt ctgggcttcc ttgaacaaat cctgcaagcg
    25681 caattgatct cgtccaatca aggactcttt cacgataatc atcatgtcct caatcttata
    25741 ctcatcccgc aagatagtcg tgtgattttg tgcaaactcc tcttttttct tggctaggat
    25801 atttgaaaaa gccaaaaaga ggtcaatggt cgtcttgtca tgcacaagct ccgcatcttc
    25861 gtaaatcaac tctgtcggcg ctttggaata atactgggcc cgttcttggt gcttggcttc
    25921 caagtgctca cccaagagct tgaacttgcg atattcttcg atttgagaga ggaggtcctg
    25981 ctccaggtca tcccccaagt ctgtcacttc tgctaccttc ggaaggagtt tacgactctt
    26041 aatcagcatg agctgactag ccatgaccat gtactcaccc gtcacttcca gacgcatggc
    26101 ctgcagggtt gagacatagg ctagatactg ttcgatgact tccgtaatgg gcacatcgta
    26161 gatatccatc tggtacttag aaaccagatg caagagcaag tccaggggtc cttcaaaatc
    26221 ttttaattta atatccatta tctatatttt tctaaggtca ggactgtttt taatcctaat
    26281 ttttttgcaa tttcgtacaa atcgaccttg ttttctattt gtcttaaaat aaactgttca
    26341 cgtaagactt gagctgataa ggatggaaaa cctttctcct tgacaaaaga ttctaactga
    26401 cgaaaggccc actgacgaga atagggtttc cctcctcttt caaaaagata ggtctgcccc
    26461 atcaagggtt ccaattctga aagcaaggcc gtgggaatgg tgacaatcct ctgttgggaa
    26521 gccttgctga ttcgcaacac ctgaaaatcc agattgatgt ccgcaacctt gatggctaaa
    26581 atctcactgg gcaagagccc catttctagg attaagagcg ctagcaagcg gccctctgga
    26641 tggtcgcttt cctgccaaaa agagtctagg tatagaatct ctggcttttc cgtcttcttt
    26701 tcagcttgtt tggctaattc caagcggtaa aagctgtcca cctctccttt ttgatagaga
    26761 aagtagagaa attggttaca ggccgaaatc tttcgcttct gggcgctgat ttttagattg
    26821 gctagctggg cttggtaaat cttgagactg gtctcagaaa tccgctcacc taccatgtct
    26881 aaaaattgct ccaaatcata cttataggac tgcttggaat tgacagacaa gccctgcttt
    26941 tcctctaaaa aggctgaaat cctgtctctc attggcatcg aatctcatat tccttactaa
    27001 aatcatgcaa gagggcatta acggccttga ggatggactt gcgcgtaata atcccttgga
    27061 aaataccctc tgtatccaca accggtaaga aggactcatc tactagcttg tgcaagacct
    27121 ccgtaatggt gaaatcaggc gaaacaaccg ctacgtccgt ttttgtcata tgaacgatat
    27181 ccgtatccgc catgatttct tggctcaagt catgctccat ctgataagcc ataatatctc
    27241 tgagtccaat cgtcccaaca aactgttttt catctgtcac aacgggaaca cgggtatagg
    27301 tcatctgact gagcaagagg gtcgcatgat ccgcattgtg ggtatcaatc aacacagcta
    27361 gatttttagc aggggtcaaa aaagtttcct cctgccccaa caagaaagtc tcaaactcct
    27421 tggcaatcat cggctaaact ccttggacaa acctggatac acctcgtgat ctcgtgtcaa
    27481 aaagtccact ttgaagtaac tatcatcaat ctccacacga gcatagagac attctctgat
    27541 ggtacctcgt ggttgactga tagaacctgg atttagaaag aggatcttgc cttccaacca
    27601 agcacttggc acatgcaagt gaccatagag gcagatagcg gcctcttcct cctgagccca
    27661 gtagtccaac ttttgaaagt tgaaattgat gtcaaacaag tgaccatgag tttggataat
    27721 cttggtcgaa ccaagctcag tcaccagacg ttctgggtag ccggcgtaga agtccatgtt
    27781 ccctttaaca acgcggatgc cctcccaaag tggagaatcc ggacgtagtt cagaatcgcc
    27841 gttatgaaaa acggcatcga ctttgcccac atagcgatca cggacttctt ccacaatcaa
    27901 gctatcgcca tgggaatcgc tcattacaat gatggtttgc tttgccatga tggaaatacc
    27961 tccaaaagtt tcttaacggc taaggcacgg tgagattgac tatttttttc ttccagggtt
    28021 aattcagctg atgactcacc tgtctctcct acaaggaaga ggggatcata gccaaagcca
    28081 ttttcaccct taggttcaaa gttaatataa cctgaccagt ctgcttcaac aactaaactt
    28141 tccttatttg ggctggctac gactagggtt gtgtggaact gagccgagcg gtccttgagt
    28201 tcaaagacca tggccaattc gtgcaagagt ttggcattat tttcacggtc agttgctccc
    28261 acacctgcga aacgagctga ccagacgcct ggtaagccac caaggacatc gactttgaga
    28321 ccagaatcat ctgccaaaac catcttgccc gttaattgag aaatggtttc tgccttaagg
    28381 cgggcatttt cttcaaaggt catacctgtt tctgctactt caggcaggtc agggtagtca
    28441 ttaagatttt ccacatcgta gcctaactta tcaaagatag ctcggaattc cttggtttta
    28501 ccttcgttac gagtcgcaat caacaaggtt tctctgacct tgcttgtctc aaagaaatca
    28561 tgaacattga ccccttcttt aggcaattct acatacaaga gttgcccatt ttcaaccaag
    28621 agcagggccc catgacgttg aataacttcc aagtttcgtc ccatttcttg attaagcatg
    28681 tctaccacaa aggagaacaa acggtaggta gaaccatagc gtaaaacagt aactgaaagc
    28741 gggaaaccat actcttcatc tccaaatatt ttggagaatt caaacagagg aaaatctgtc
    28801 ttatagtcgc tcaaactgtt aacgccacca aaaatactat aagacccaac ataccagtcc
    28861 tggtcatcct tatattcata aattttattt gtcataattc tacatgctcc acatgaatct
    28921 ctttttccag ccattcttca ccaatttgtg caaaactttg gctactggct gttgtgtaaa
    28981 aacggtgatg gagtggtcca gcatcgcgac cacgattgat ttcaaaataa ttgagtaaga
    29041 ctgagatatc ccgtacgcac tctgccccac tatcgatgag ctgaaccttt ggccccatca
    29101 cattttggat aatagggcga aggagtggat aatgagtaca gcccaaaatc aggctatcca
    29161 cctttccaac caagggacgc agggtttcat agaccacctt cttggtaaca ctggttgaca
    29221 gggcacctga ctcaaccaag ggagcaaact tgggacaggc caagctctcc acctgtaagt
    29281 cgggatccag atcatggatt ttctgacggt atatgtctga ttgtaccgtc atgggcgttc
    29341 caatcactcc gattttccca ccttgactgg acttgatggc tgccgaagct cctggcaaaa
    29401 ttacacccaa gacaggaata tctagttgag ccttgatttc ttcccagacg accgcagtcg
    29461 cagtgttaca agcaatgaca atcattttga catccttggt caagagaaag ttgaccagct
    29521 gccaagtata ttcacgaatt tgctcagcag gacgggggcc atagggcgcc cgcgccgaat
    29581 ctccaatata gacgatttct tcatggggaa gctggcgcat gagctcgcgc acaacggtca
    29641 agcccccgac acccgaatcc aaaaaaccaa ttggtcgatt atccatacag tcttctttct
    29701 agtctttttt ctgattgatc gttcattatg attccttgta ctgaacgaac tgaccgacag
    29761 cttgatagaa tgtcaactac ctctctctta atcataatca aatatcaata gaatgcaagg
    29821 aaaaagtctc atccctaaac cataaccaac atagtgagaa gtctggaact ttcatcccag
    29881 acttttcctt atttattttt tctttttatt gttagcaagg gctgcctttt gttggcggat
    29941 gatttggtgg taaacttgtt gtaccttagc ttcgcttggt ttttgaccat ttgcactcaa
    30001 aagagtacga actgcttcag cattcaaacg tgggttgtca gcaaattctt tttcgatttg
    30061 cttacgaacc aagtacattc ctccaagagc tcctcctaga aaagctagca caatcaatac
    30121 aattgctaaa agtaaatcca tcatttttct cctgtttctt tttgaatccc tttcattata
    30181 ccacaaacta gccaccctga ccagtttgtt ctacactttc aaggatggaa tagacagcaa
    30241 aaagaaccct gcttttctga aaaagaggtc tccttgctaa gtttatactc aatgaaaatc
    30301 aaagagcaaa ctaggaagct agccacaggt tgctcaaagc accgctttga ggttacagat
    30361 aaaactgaca cggtttgaag agattttcga agagtattaa tttacataaa tagccagtgt
    30421 ttgatagggt ttgagtagaa ttttctcaga cacttctgca tcttcatagt ttgaaatcaa
    30481 aatctgtcca ttttggtaga ctgctggcaa gtcgatttcc acttctttgg cataaaagtt
    30541 attgagcact agtaactttt gatcctcaaa ctggcgttca aaagcgtaga cttgtttgct
    30601 atcttcaaag gctggtttgt aatttccttc tgaaatgatt ggcatttcct tacgcagtcg
    30661 aatcaagtct tgatagaagg tgaaaatcag acctttgatt tcattttcta cattgatatc
    30721 tttataggat ttaccgactt tcaaccatgg agtgcctgtt gaaaatcctg cattttcaga
    30781 agtatcccac tgcatgggaa tacgtgaatt atcacgcgac ttagcttgaa taatctggaa
    30841 ggcctcttgc tgactctttc cttcttctaa gagcatctga taggcattaa gcgattcgac
    30901 atccacataa tcagccatag aatcatagtc tgggtcaatc atcccgattt cctcacccat
    30961 gtagatataa ggtgtcccac gtgacaggtg aatgctggct gctagcatgg tggctccttc
    31021 cttgcggaag ttttgaatat cgacaaaacg gttcaaggca cgtggttgat cgtgattgtt
    31081 ccaaaagagg gcactccaac cgtctttatc actcatttcc ttaccccaac tatggtaaag
    31141 actcttcaac tcttcaaaat caaagggagc caaggtccac ttttgtccat ccttatagtc
    31201 caccttgagg tgatgaaaat taaaggtcat ggataattcc tgacgatcag gcgacgaata
    31261 aaggacacag ttttccatgg tggtagaaga catttcccca actgtcataa agctatcgtc
    31321 agatccaaaa gtggcttggt tcatcatacg caaatagtta tgaacgatgg gtttgtctgt
    31381 ataagctggc ttcccttcat tttcaggaca gtccactgaa acctcgtcct taccgatcaa
    31441 attgatcaca tcaaatcgaa aacctttgac acccttgtcg cgccagaaat taacaacctt
    31501 gaaaagctcc ttacggacat tgggattgcg ccagttaagg tcagcctggg tctcatcaaa
    31561 taggtgaaga tagtatttcc cagtatcccc gaaaggcgcc catgcagaac caccaaactt
    31621 agactgccaa tctgttggtt ggtcttggat gaagaaaaag tcttgataat acttatcacc
    31681 agctagggct ttctgaaacc attcatgctc tgtcgaacaa tgattaagta ccatgtccag
    31741 cataaagtca atcttgtgct ctttaccgac acacaccatt tcctcaaaat cagccatatc
    31801 accaaaaaga ggatccactg ccatataatc tgaaatatcg taaccattat cccgttgagg
    31861 gcttggatag aatggattga gccagaccat atccacacct agtttggcta aatagggaat
    31921 tttttcgata atcccacgga aatccccaat accgttttca gtggtgtctt tgtaagattt
    31981 tggatagatt tgatagacta cttttccttt atcaagtgtc atctgtttct ccttttctga
    32041 taaaagggag gaagcagtct tccgtcccta tttgtgctat ttcaattata ctcaatgaaa
    32101 atcaaagaac aaactaggaa gctagccaca ggttgctcaa aacactattt tgaggttgca
    32161 gatagagctg acgtggtttg aagagatttt cgaagagtat tagattcgtg tagcgaccat
    32221 gagagatgct ccagcttgga tcgttgtcgg ataagttcca gtaatagtcg ctgtataagc
    32281 atcttggttg gtgatgataa caggagtttc tgtcaccaga cctgcagcct taatgacatc
    32341 catatcaaaa cgaatcagtt gctggccaac tataacgtga tctccttgga ctacaagact
    32401 ttcaaaacct ttgccatcaa gacctactgt atccataccg atgtggatga gcaattcaac
    32461 tccctcgtca gagacaatgc cgatggcatg cttggtaggg aaaagaaccg tcactgttcc
    32521 attaactgga gaggtcaact caccttggct tggttcaatg accagacctt gccccatgac
    32581 acctgatgca aaaacaggat ccgtcgcttg actcaattct ttcacttggc cagttagtgg
    32641 gctgataatt tctaccgaag taagttctac tggttcatgg ctcacaaatt ctgcttcttc
    32701 ttgagcaacg aattctgcct gcaagttcgt atcgccctct atttttgtga agagaccagc
    32761 cttgcgaaag aagaaagtca agagcattgg aacaacaatc gcaactagca tagttcctgc
    32821 aaatggcagc atgtattgag gttgaataga gagaatacct ggcaaaccac cgataccaat
    32881 agaagccgca gttacattaa aagtaacgga taacatgcct gcaagggctg aaccagtcat
    32941 cccagcaaca aatggataaa tatattttac gttaacccca aaaagagctg gttctgtaac
    33001 accgagatag gctgaaatgg ttgcaggaag tgaaacctga gcctcacgct catcatggcg
    33061 atgcatgaaa taataggcaa acacggctga gccttgagca atattagaaa gagcaatcat
    33121 tggccatagg gcagtgccac cagcatccgc aatcaattgt gtatcaatgg cattggtcat
    33181 atggtgcaga cctgtgatga caaatggagc gtagagggca ccaaaaattg caccgaagag
    33241 ccatttaact ggaccagtta aacctgccaa gacaactgat gaaagtcctt gtccaattgt
    33301 ccaaccgatt ggtcccaaaa cagtatgagc caaaatcaag gctggaatca atgacaagaa
    33361 aggtacaaaa atcatagaaa tgacttctgg gatatgcttg cgccagaaga tttcaagata
    33421 agacagactc aaacctgcaa gcaaggctgg gataacttgg gcttggtaac cgatacgatt
    33481 aatagtaaaa tagccaaaat tccaaaccca gtttgccgcg atatcagctg ctggcgttga
    33541 agcaaccgca taggcattga gcaactgagg cgataccaaa cagattccga gaacaattcc
    33601 caaaatttgg ctggttccca tcttacgaga aacagaccaa gtaatcccta ctggtaagaa
    33661 ctggaagata gcttcaccag gcaaccagag gaagtgatta acccctgccc aaaactgaga
    33721 ggattctgtg atggtcttgc catccaacat cgaccaatgg acaccttcca agacattacg
    33781 gaaaccgagg atcaatccac caacaatcaa ggctggaata atcggagtaa agatttccgc
    33841 cagagtggtc ataacacgtt ggaccacgtt ttgattactc ttagctgcag acttggctgc
    33901 ttctttggaa acaccctcaa tacctgaaac ggctgtaaaa tcattataaa agatgggcac
    33961 gtcatttcca atgattacct gaaattgacc tgcatttgta aaggttcctt taacagctgg
    34021 aattgactcg atagctttaa cattagcctt cttatcatct cctaaaacaa accgcatccg
    34081 tgtcgcacag tgagttacgg cagtcacatt ttctttgcct ccgattgcct gaagcagatc
    34141 tttggcttct tgttcaaatt ttcccatttg attctcctta tacttgtcaa agcaagtttg
    34201 atttgataag tatattgtaa acgataccaa acttgtctgc aacttgtttg gtataaaaag
    34261 ggtgtttttt tgtaaatttt ctagcacttg tatggtaaaa tagatacagg tgttcattaa
    34321 actagactaa aaacctattt aagcaggcaa aatgaagaaa taccaacaat tatttaagca
    34381 aatccaagaa accattcaaa acgagactta cgctgtcgga gatttccttc ctagcgagca
    34441 cgaccttatg gagcaatatc aagtgagtcg tgataccgtc cgaaaggccc tgtctctcct
    34501 ccaagaggaa ggattgatca aaaagataag agggcaaggt tctcaagtcg tcaaagaaga
    34561 aaccgtcaat ttccctgtat ccaacctaac cagctaccaa gaactagtta aagaacttgg
    34621 actgcgctct aaaaccaacg tggtcagtct ggacaagatt attattgata aaaaatcctc
    34681 actgataacc ggtttcccag agtttcggat ggtttggaag gtgggccgcc agcgtgtggt
    34741 ggatgatctg gtatccgttc tggatacgga ctatctggat atggaactca tcccaaatct
    34801 cactcgccaa attgctgagc agtctatcta ttcttatata gaaaatggcc tcaaactcct
    34861 tattgattat gctcagaagg aaatcaccat tgaccactca agcgaccgag acaagattct
    34921 catggacatt ggcaaagacc cttatgtcgt ttcgattaaa tcaaaagtct atctccaaga
    34981 cggacgccaa tttcagttta ccgaaagtcg ccataagtta gagaaattta gatttgtaga
    35041 ttttgcaaaa cgcaagaaat aaaagactga gacaccagat ctcagccttt ttcggctcta
    35101 taatatttgt agtgggtaaa tcccttatag atattatgga gcctattttg ttatagaaaa
    35161 aaagtcccat atgacctata atgaaaagcg acaaaaccat cattagaaag attcatatgg
    35221 aacaattaca ttttatcaca aaactgctcg atattaaaga cccaaacatc aagattctag
    35281 atatcatcaa tatggatacc cacaaagaaa ttatcgctaa gctggattat gaggctccat
    35341 cttgccctga ttgtggaagt ctaatgaaga aatatgactt tcaaaaaccg tctaagatcc
    35401 cttacctcga aacaactggt atgccttcta gaattctcct tagaaaacgc cgtttcaagt
    35461 gctatcactg ttcaaaaatg atggttgctg agactcccct ggtaaagaaa aatcaccaaa
    35521 tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaaaatg tctatgactg
    35581 atattgccca tcagctttcc atttcaactt caactgtcat tcgcaagctc aatgactttc
    35641 actttgagca tgatttttct cggcttccaa agattatgtc ttgggatgag tatgccttca
    35701 ctaaggga
//
LOCUS       DAVFJR010000019        33778 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVFJR010000019 DAVFJR010000000
VERSION     DAVFJR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.020"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(121..279)
                     /locus_tag="VU722_001159"
                     /pseudo
     CDS             complement(121..279)
                     /locus_tag="VU722_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(551..1240)
                     /gene="rplA"
                     /locus_tag="VU722_001160"
     CDS             complement(551..1240)
                     /gene="rplA"
                     /locus_tag="VU722_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU1772145.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNEIIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1449..1874)
                     /gene="rplK"
                     /locus_tag="VU722_001161"
     CDS             complement(1449..1874)
                     /gene="rplK"
                     /locus_tag="VU722_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU1772146.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGIEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2193..2909)
                     /locus_tag="VU722_001162"
     CDS             complement(2193..2909)
                     /locus_tag="VU722_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU1772147.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGATPKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYEIQNKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(2912..3382)
                     /locus_tag="VU722_001163"
     CDS             complement(2912..3382)
                     /locus_tag="VU722_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU1772148.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMIAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(3384..4421)
                     /locus_tag="VU722_001164"
     CDS             complement(3384..4421)
                     /locus_tag="VU722_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU1772149.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVFA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(4519..5844)
                     /gene="brnQ"
                     /locus_tag="VU722_001165"
     CDS             complement(4519..5844)
                     /gene="brnQ"
                     /locus_tag="VU722_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU1772150.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAVYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEEMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVKFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6015..6107)
                     /locus_tag="VU722_001166"
     CDS             complement(6015..6107)
                     /locus_tag="VU722_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1772151.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6150..6302)
                     /locus_tag="VU722_001167"
     CDS             complement(6150..6302)
                     /locus_tag="VU722_001167"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1772152.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6462..7040)
                     /locus_tag="VU722_001168"
     CDS             complement(6462..7040)
                     /locus_tag="VU722_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU1772153.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7094..8494)
                     /gene="pepV"
                     /locus_tag="VU722_001169"
     CDS             complement(7094..8494)
                     /gene="pepV"
                     /locus_tag="VU722_001169"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU1772154.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKVDAEHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKDYLDIAGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8507..9112)
                     /locus_tag="VU722_001170"
     CDS             complement(8507..9112)
                     /locus_tag="VU722_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU1772155.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTNLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9283..10083
                     /locus_tag="VU722_001171"
     CDS             9283..10083
                     /locus_tag="VU722_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772156.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGYYLPDQSQLQ"
     gene            complement(10269..11102)
                     /locus_tag="VU722_001172"
     CDS             complement(10269..11102)
                     /locus_tag="VU722_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU1772157.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSKYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGAIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLSSLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11092..12939)
                     /gene="uvrC"
                     /locus_tag="VU722_001173"
     CDS             complement(11092..12939)
                     /gene="uvrC"
                     /locus_tag="VU722_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU1772158.1"
                     /translation="MNNLIKPKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVRAANEIKRLLDRIFPFRKCTNLPSKVCF
                     YYHIGQCMAHTICKKDEVYFKSMAQEVSDFLKGQDDKIIDNLKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQISTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILPQVAEERVDYQMEGNYNEP"
     gene            complement(12978..13667)
                     /locus_tag="VU722_001174"
                     /pseudo
     CDS             complement(12978..13667)
                     /locus_tag="VU722_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
     gene            complement(13746..14978)
                     /gene="murN"
                     /locus_tag="VU722_001175"
     CDS             complement(13746..14978)
                     /gene="murN"
                     /locus_tag="VU722_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU1772159.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     IKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14983..16203)
                     /gene="murM"
                     /locus_tag="VU722_001176"
     CDS             complement(14983..16203)
                     /gene="murM"
                     /locus_tag="VU722_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU1772160.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDAGQARVPLAATLTLEFGQTSVNLYAGMDEDFRRYKAPILTWY
                     ETARYSFERGILWQNLGGVENNLDGGLYRFKANFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16315..17094)
                     /locus_tag="VU722_001177"
     CDS             complement(16315..17094)
                     /locus_tag="VU722_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU1772161.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNVTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEGFLTTLPIDFKLEERLT"
     gene            complement(17163..18824)
                     /locus_tag="VU722_001178"
     CDS             complement(17163..18824)
                     /locus_tag="VU722_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU1772162.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18999..21221)
                     /gene="recJ"
                     /locus_tag="VU722_001179"
     CDS             complement(18999..21221)
                     /gene="recJ"
                     /locus_tag="VU722_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU1772163.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEEM
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQYFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESHIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21497..22165
                     /locus_tag="VU722_001180"
                     /pseudo
     CDS             21497..22165
                     /locus_tag="VU722_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22163..22849
                     /locus_tag="VU722_001181"
                     /pseudo
     CDS             22163..22849
                     /locus_tag="VU722_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            22862..23539
                     /locus_tag="VU722_001182"
     CDS             22862..23539
                     /locus_tag="VU722_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1772164.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYSLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYTAEVIRSGIQSIPSGQMEVALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGVALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23549..24208
                     /locus_tag="VU722_001183"
     CDS             23549..24208
                     /locus_tag="VU722_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1772165.1"
                     /translation="MESILEVLSPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24502..25692
                     /locus_tag="VU722_001184"
     CDS             24502..25692
                     /locus_tag="VU722_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU1772166.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTAHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FVSIILVAYLGKYIQYEAWRWIHRMVYLAYIFGLFHVYMMMGNRLLTFNLLSFLVGSS
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQAGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQVGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26012..26893)
                     /locus_tag="VU722_001185"
     CDS             complement(26012..26893)
                     /locus_tag="VU722_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU1772167.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27034..28362)
                     /gene="vncS"
                     /locus_tag="VU722_001186"
     CDS             complement(27034..28362)
                     /gene="vncS"
                     /locus_tag="VU722_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU1772168.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQFF
                     SGNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28359..29015)
                     /gene="vncR"
                     /locus_tag="VU722_001187"
     CDS             complement(28359..29015)
                     /gene="vncR"
                     /locus_tag="VU722_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU1772169.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29064..29147)
                     /gene="pep27"
                     /locus_tag="VU722_001188"
     CDS             complement(29064..29147)
                     /gene="pep27"
                     /locus_tag="VU722_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU1772170.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29294..30673)
                     /gene="vex3"
                     /locus_tag="VU722_001189"
     CDS             complement(29294..30673)
                     /gene="vex3"
                     /locus_tag="VU722_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU1772171.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSFKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIDTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AVQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIVFVLALVLVVAVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30725..31372)
                     /gene="vex2"
                     /locus_tag="VU722_001190"
     CDS             complement(30725..31372)
                     /gene="vex2"
                     /locus_tag="VU722_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU1772172.1"
                     /translation="MTLLQLQDLTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31499..32776)
                     /locus_tag="VU722_001191"
     CDS             complement(31499..32776)
                     /locus_tag="VU722_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772173.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VETNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVS
                     GEQSVERDDLSAADKNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHGKIALDAGQSEAGKGQTVEFEIVGIFSGKKQEKFTGLSSDFSENQVFT
                     DYDSSQTLLGNSEPQVSAARFYVENPKEMDGLVKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKTSIFLQF
                     CLEVVLVSLGALLPAFVVGNAITSYLLQTLLASGEQASLQDTLAKASSLSTNILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(32927..33484)
                     /locus_tag="VU722_001192"
                     /pseudo
     CDS             complement(32927..33484)
                     /locus_tag="VU722_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035094.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         9510 a         7732 c         6316 g        10220 t
ORIGIN      
        1 aagagtatta gaaagctcga tggactattc cagattcatt ccactaaatt tcgaaatcga
       61 gtaggggata atctctagct cctcttacac caccgtacgt gccgttcggc atacggcggt
      121 tcaactaact tttaacgcat gtcgttcagg ataataatcc aaacagaaaa ccagtccaca
      181 tttttcaagg actggttttg atatagcacg tttaagcacc gacttctgat ctactaattg
      241 atagtggtcg ccccagccag ataccttatc cgctatatac gccttattat cacgtccctg
      301 ttcgtagaac cacgatttcg ctatcccttc ctctgacgat tcttatttcc agcgtcagac
      361 ttaaaacggt ctatctccag accgttttaa tccgctacct cacgatagtc agacttggga
      421 atcgctattg ggttcaccgg tagcaggtgc ccaccgagaa cttacacctc agatgtatga
      481 cgggcatgtc atacatcaaa aaagttgaga catagcgtct tcaacttttt tacattactt
      541 taactactga ttaaagtgag tttacgtcaa ctttgatacc aacaccttga gtagttgtga
      601 tagtcaagtt tgttacgtaa gttcctttag ctgtagctgg ttttgctttt tggattattt
      661 cgttgaaagc tttaaagttt tcaaccaatt tttcagcttc aaatgatact ttaccaatga
      721 ttgcttgaac gttacctgca cggtcagcac ggtaagtgat tttaccacct ttagactctt
      781 caactgcttt agcaacatcc attgttacag taccagtttt agggtttggc atcaagttac
      841 gtggtccaag gacacgtcca agacgtccaa caagagccat catatcaggc gtagcgataa
      901 ctacgtcgaa gtccaaccaa ccgtcgttga ttttagcaac aaggtcatct tcaccaacaa
      961 agtctgcacc agcagctttt gcttcttcag cttttgcacc acgtgcgaaa acaagaacgc
     1021 gtgaagtttt accagtaccg tttggcaata ccattgctcc acggatttgt tggtcagctt
     1081 ttttaacgtc gatgttcaag ttgtaagcaa cttctacagt tgcgtcaaat tttgcaaagt
     1141 tagtttcttt tgcaagtgct acagcttctt ctacgctgta tgcttttgtg ctgtcgattt
     1201 tctcaagagc agcacgaagt tgtttgcttt ttttagccat tttctattct ccttgtaagt
     1261 ggttcaatcg attttcatct cccacgtcac ttctcgaaat gatgaagtct tgcgggtttt
     1321 cagtctacta ttttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag
     1381 cctcagtcac ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt
     1441 gttattgatt agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc
     1501 attgcagact ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt
     1561 acttgtgcac gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca
     1621 atacctgcag cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat
     1681 gatttatctt cataaactga gataacaact ggaatgatca taccagcttg gtcagctgta
     1741 cgagcgttga actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt
     1801 ccaaccggtg gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg
     1861 acttttttag ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac
     1921 ctcccacaag tatgtttttc acatacttac ctattataca ctatttatct ggaattgcaa
     1981 gagaaaagtt tattttttat attcaatgaa aatcaaagag caaactagga agctagccgc
     2041 aggctgctca aagcacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca
     2101 ctgttttgag gttgtggata gaactgacga agtcagtaac atacgcacgg taaggcgacg
     2161 ctgacgtggt ctgaagagat tttcgaagag tattaatcga cgtagtctcc gccttcaaag
     2221 ccatagtatt cttccaaact gagaccactc tcagcaattt ctttagcttc ttttcctaca
     2281 taacgcaggt gccattcctc agccatatag cccgtttctt tttctttacc tttaagataa
     2341 cggacaacaa aaccataatc agccgcatgg tccaggagcc attgagctgc tttttcttct
     2401 gtcaccaaat caccatcagt cccaataaca tcaaaggcca agcctgtttg gtgttcacta
     2461 tagccaggtc gggcagagta acggtcggca gcttctttcc cgtcttgatt gacataatct
     2521 tgatagagct tgttctgaat ttcataactt ctaaagccac tgtaatggtc actgattggg
     2581 aaacctgcct cttgcatcgc tttgatgagt ttgaccaact ctgccttggc tgttggattt
     2641 tcccctggat tatagtcttt agacaatgga tagtgtttat ttgctacgat gatttcatcg
     2701 tatttaccct gaatgctgta atagtctcct ttgttaacca cttctgcttt ttttggggta
     2761 gccccttgag acttgcttcc gactgttcca tcagccttgg ctgtttgttc tgtcttagct
     2821 gctccatctt cattttttgc tttttcttgt gaacaagctg ctagactcaa ggctagcaag
     2881 gctgtcaaga caaggtatct ttttttcatc tttactcctt tatttctaat agtttatcta
     2941 cttctgatga taaacgttcg actaatcttt taatctcatc aggttttgat tggcagattt
     3001 ctgctatcat ttcttcaaag ggaatccacc atactggacc acgtccattg aggccataac
     3061 cattcatatc acctcttcgt ctaggaaaca gatgccaatg aagatgggca tcgccatttc
     3121 ctagcagttc gatattcatt ttctcagcag caaaggcctt ggcaactgcc tcttggacca
     3181 cactcatttc ttctagaaaa cggagtcttg tctccttttt caaatggtgc aattcggtga
     3241 catgttcctt ggctagaaag agactatagc ctgcaaaata ctggtggtct ccaatcacaa
     3301 gatagcctgt ttccaactct ttgacaaaat agggattttc tcccttcttg atgagctcaa
     3361 ttctctgaca tataaggcac atatcaatct actaaattgc ttctaagata ggcatcgacc
     3421 attcgttctg ttgcgaccac cgagtcaata tgagtgcgct cataagaatg actagactcg
     3481 atacccgcac caagaagggc atgcttgacc tctgcccctg cagacatagc cgctgaagca
     3541 tccgaaccat aaaatggata gatgtccagc ttaaaaggaa tatcttgctc tttagcaaag
     3601 acaaccaagt gttgacggaa gtcatagtga taaggacctg aagcatcctt gacacagata
     3661 gatactgtgt actcatctgt ctgctggtca tctcccatag ctcccatatc cacagccaga
     3721 tattctacta cctgagcagg aatgttagaa ttagcaccat gtcctacttc ttcaaaaact
     3781 gaaaaagcaa aatgagttgt tactggcaat tcaatcttct ctttcttata aatacgaagc
     3841 aggttgagca aaatcgctgc gctgacctta tcatccaaat gacgagactt gataaaacct
     3901 gtatcagtca caacagttcg tggatcgaag ctgataaaat caccgacctc aatcccaaga
     3961 gcacgagttt ctttttcatt gcttactttt acatccaaac gcacttccat attgtcctgc
     4021 gtgcgttctg cagttcctgc atccttgtag acatggcaag aagtttggtg gatgaggatg
     4081 gttcctgata ccttttgacc tgtgctagcc acatgaacgg tacagttttc accttcaatc
     4141 atgttccaag gaaaaccacc gatacggtcc aatttaagac gaccatctgg tttgacagca
     4201 cgaacaatag cacccagcgt gtccacatgg gcagtcacat agcgatgttg ctcatcattt
     4261 tgacctttga tggtcacatt gacaccaccc ttggctgtgc gaactggctg gtaaccaaaa
     4321 ccttctagag tcttgactaa ataattcgaa atttcacgag tgaagcccgt tggcgatgcg
     4381 atggctgtca gttctttgat atattctact gtttgattca tttcttcacc tctttcgcta
     4441 cctattataa cacatttatc atcggataaa aaaagaaaat cactcctgta gacttggcta
     4501 caaaagtgat ttaagtgatt attccatttc aaaaacatcg ctttcttgct tgtttggtag
     4561 aaccaatgag agcaagattc caacaatggc tggcaccaac catgggagag atgccttggc
     4621 aaaaggaaga acgctaacaa gatttgcaag aaacttaacc ttaaacgagc ttcctagtac
     4681 gcttgcaatg gcaataactg taaccacagc aattgtcaac tgcatacctg gttttgaaag
     4741 ggcaacaaat ttgttgacaa tgacaatcat aacgatagca atcgtgattg ggtacaagat
     4801 aaccagtact ggaattgagt acttgataat cgcatcaaga cccaaattgg caatagcaaa
     4861 tccaatcaag gtaaaggctg tcgcataaac cttgtagctg atttgtggga agcgctcatt
     4921 aaagaactca gctgttgaca caatcaaacc aacagtcgtt gtgaagcagg ttacggtaac
     4981 catagctgca aggaagagtt gagctgttga gccaaagatt tcttgagtgg cttgtgacaa
     5041 gatgtaaaca cctggtgtcc cacccttcat ctcttcagct ggtactggga aatgatttcc
     5101 aagaaaacct aaaccgatgt aaagagcgct gaaggcaagg gcaacaacga taccaacaac
     5161 ccaaatagtt gaaatgtatt ctttcttact tgaaaatcca agttgtttca aggtttgaac
     5221 tgcgattacg ctaaaggcca ctgaggcaag ggcgtccaag gtattgtaac cttctaggaa
     5281 acctgtacca aaggcagaag cttgataaac agctgaagca gcttgaggac ttgttccacc
     5341 atatttgata gctcccagaa cgaccaagat aacaatcaaa attgcaaaga ctggcgttaa
     5401 aatacgtcca atgcggtcta agatttttga tggattaagc gaaatcaaat aggctgccgc
     5461 aaaatacaga accgtaaata caatcaagcc aagtccttta tttgcatccg acaaaagggg
     5521 gctaatccct acttcgtaag ctgttgtagc agtacgtggg gtagcaaaga atggaccgat
     5581 tgacaagtaa agaactgaga ggtaaagagt cgcaaaccaa ggcgctatct tcgttgaaat
     5641 ctcgtagata tatcctttag gatttagcgt tccaataata agggtcaaga cggcgatacc
     5701 aacgcctgaa aagacaaaac ctgcgatggc aggaagaaaa tgttctccag atagagcacc
     5761 tagagaaggc ggaaaaatca agttccccgc accaaaaaat attccaaaca ggagcaaacc
     5821 tgttagggta ccttttttag ccataaaaat ctccttcata tttataaaat actgacctag
     5881 tataccacga ttaggagtct gaaaaaagca tcacgaggca aatattaaat gttttcaatt
     5941 ttcttaaaaa taagaattat ctaaaaataa aactctccta cccagtccac accaagtagg
     6001 agaaatgcaa aattttaaag ttcttcaaag gctaacatgc caccctggac attgataaca
     6061 ttataacctt gttctaatag gaattggcaa gcacgcgccg atctcattcc agatttgcaa
     6121 ataatataat gcaagcgatc tttgtccaat taatcataac tatcagccaa ttgactaagc
     6181 ggtaggttgt gggcaccttc taaatgaaga gctgcaaact catccacttc tctcacatcc
     6241 actagagaaa gctggtcgtt ttggtaaagc tggtaaaatg cgtcaaaggc tatttctttc
     6301 attctttttc ttctaatact cttcgaaaat ctcttcaaac cacgtcagca tcgccttacc
     6361 gtgcgtatgt taccgacttc gtcagtttta tctgcaactt caaagctgta ctttgagcag
     6421 cctacgacta gcttcctagt ttgctctttg attttcattg actataaaat ggttttaatt
     6481 ctttttttca aatctggcac tacttctgcc tcaaaccaag gatttttggc catccagatt
     6541 tgatttcgtg gtgatgggtg aactagcgga aaataggctg gcagatagtc tttataatgt
     6601 ttcaccctct ccgttacctt cccactgatt ttctcctgta aatagtaggc ttgggcatat
     6661 tgcccaatca agagggttaa ctgaatatca ggcaattcct gtaagagctg cggatgccat
     6721 ttttctgcaa aacctgtacg aggcggaaga tcacccgact tgccatgtcc tggaaagtag
     6781 aaatccatag gcaaaacagc aaaataacct gaattgtaaa aggtatcttc atccacacct
     6841 agccagtccc gcaagcggtc accactttta tctttccagt aaaggcctgc ttcttgagtt
     6901 ttaagtcccg gagcctgacc gatgatattg atgcgagcag tttttggcgc tgcaaagaga
     6961 ggctcaatgc cacgctctgt atagctggca ttctgcgaat ccgccatgat agcctgtttg
     7021 attctttcga tttgagacat ctactttccc tccaaaaaga agtccaagca taagatctca
     7081 gacttctatc gttttatttg atcaattcgt aaatagcttc ggcataaatt gctgctgctc
     7141 ggaagagatc atccaaggca ataaattcat tggcttggtg catggtatca attgagtctg
     7201 ggaacatagc accataggca actccgcgct ctaacaagcg accaaaggtt ccaccaccga
     7261 tgacttgttc atgaccttta aggcctgttt gtttttcata gacattcaac aaggtttgca
     7321 caagtggatc ttccattggc acatagtgag gcgtgtgacc gtgttcagac aggctaacag
     7381 aaacaactgg caagttttca aggattgact tgatttgttc tggacttgtt ccttttggat
     7441 agcggatgtt gagagcaatg gtattatcag cacttgtttc atcgaagcgg aagacgcctg
     7501 cattcataga aagggcaccc atcttttcat ccacatgagc gatcttaaga ctttcaccct
     7561 catggtcgtt caagagaatt ttaccagcga tgtcaaggta gtctttggct ggaccagcaa
     7621 agtcaaactg gctaaggaag agggctaggt aagtcgcacc attgacacct gaagcaggca
     7681 tagcaccgtg ggctgattta ccaatgatcg tcaccttgta tttgccagct tcttcttgga
     7741 gttctcctct aagtttgtgt tctgcaacaa aggcatctag tttagcttgc aaatcagcca
     7801 aatcacctga aacgactgct gttgctgatt ctggtaccat attttcacgt aaaccacctg
     7861 taaagctgtg aagacgggca gcacctgtat tttctcctgc aaagtggagg tattccgtga
     7921 tatttccttt ttcaccattg atgataggga attcagcgtc tggagagaaa ccgaaatctg
     7981 gtttggcaag tcctacgtgc tcaaagtagt agtccatgtc tgcccagcct gattcttcgt
     8041 ctgttccaac gatgaagcga actttcttag aagttggaag acccaattct ttgatgattt
     8101 tcaaaccata gtaacaagct gttgtaggac ccttatcgtc cgaagccccg cgcgcataaa
     8161 ggcgaccatc tttgatagtt ggtgtgtaag gatctgtgtc ccaaccgcta ccagcaggca
     8221 ccacatccat atgggcaaag attccgagaa cttcttctcc atcaccaaac tcaaaatgtc
     8281 ctgcgtagtt atcgacattc ttagttgggt agccatcacg gtctgcgatt tcaaggaatt
     8341 tctccaaggc ttttactgga ccaggcccaa atggatgttc agcatcaacc ttgctgtcat
     8401 cacgttctga attgatttcc aaaaggctaa acaagtcagc caagaggtct tctttgcgtt
     8461 tttctacttc tgctgtaaaa tcaattgctg tcattttttc ttctttctat cttttctcga
     8521 tgatttcatc tactggcaag cggtagcttg gttccaattt ttcgtctgta taacccactg
     8581 tgatcaagag ttctgggcgg aaacggtctt caatttccaa aacctcattg acttttgatt
     8641 tgtcaaatcc aagaataatg ttagaaccaa ttccttggtc tgtcaatgca agaactaagt
     8701 tcatggcaac caaacctgca ttgagagcta ggtagtcgct gacttgttgc tcactgtaac
     8761 gggcaaactc agctggcaga tttttcataa aatattgaag ttgctcttca gaaaagttat
     8821 tagcaccacc aacacgggca atcttacgag cacgtttggc taagttcgta tctgtaaaca
     8881 aggcaatggt tacaggcgct gatgatacct gctcaaagtt tgaaccataa gccaactttg
     8941 ccagttcagc atttttctca cgaacaacta caaatttcca aggctggctg ttgtgggcgc
     9001 ttggcgccaa ggttgcaatt tcgatagccg tacgcacatc ttttggatca acaggcttat
     9061 cagtgaaatg cttggtcgca tgacgttttt tatttaattc aagaaatttc ataatcgatt
     9121 tccttttcta attctactgc ttccattcta ccataatttg aaagagcttg cagggatttt
     9181 tcatgattaa gtttttctat cacagacata aaagatatat attggtttat caggaacatt
     9241 tctgataaac tagcaagtac tttacatttg aatggagaca gtatgaaaaa atttagccta
     9301 ttactagcta tcctaccatt tttggttgcc tgtgggaatc aagctacacc caaagagact
     9361 agcgctcaaa agacaatcgt ccttgctaca gctggcgacg tgccaccatt tgactacgaa
     9421 gataaaggca atctgacagg cttcgatatc gaagttttaa aggcagtaga tgaaaaactc
     9481 agcgactacg agattcaatt ccaaagaact gcttgggaga gcatcttccc aggacttgat
     9541 tctggtcact atcaggctgc ggccaataac ttgagttaca caaaagagcg tgctgaaaaa
     9601 tacctttact cgcttccaat ttccaacaat cccctcgtcc ttgtcagcaa caagaaaaat
     9661 cctttgactt ctcttgacca gatcgctggt aaaacaacac aagaggatac cggaacttct
     9721 aacgctcaat tcatcaataa ctggaatcag aaacacactg ataatcccgc tacaattgat
     9781 ttttctggtg aggatattgg taaacgaatc ctagaccttg ctaacggaga gtttgatttc
     9841 ctcgtttttg acaaggtatc cgttcaaaag attatcaagg accgtggttt agacctctca
     9901 gtcgttgatt taccttctgc agatagcccc agcaattata tcattttctc aagcgaccaa
     9961 aaagagttta aagagcaatt tgataaagcg ctcaaagaac tctatcaaga cggaaccctt
    10021 gaaaaactca gcaataccta tctaggtggt tattacctcc cagatcaatc tcagttacaa
    10081 taacactctt cgaaaatctc ttcaaacaaa ccacgtcagc tttatctgca acctcaaagc
    10141 tgtgctttga gcaacctacg gctagcttcc tagtttgctc tttgattttc attgagtata
    10201 agatatacta aaagcgattg gaccagccaa tcgctttttt agtttgcatt ggctatttta
    10261 ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct ctacataccc atgcttttct
    10321 attaagctgg ataataattc cagattgtgc ccctgatagt tatcgtcacg acgcagttct
    10381 tcatacattt cgataaaggg aagccccttg gacttggcca attctaactc agcttcgtaa
    10441 tcataagcaa ctttacgaaa ttggatattg agtaattccc catcttcaac ttctatcacg
    10501 gcatactggg cacggtgatt ttttaacgcc tcccaattaa aatagggcat gccaatcgcc
    10561 cctggattga tgatttgttg cccttgactt ccataacgaa gcaactgctt gtgaacatga
    10621 ccataaactg ccacgtccgt ttccgcatct agcagttggt caaatttctc tgtatcattc
    10681 tcaactagca agtcaccacc atagtttttg tcaggtaaat tatgagagat agaaaagcgc
    10741 aatccgtcaa tttctttctt ttccagcaaa ggcaagcttc gtagccagac aatcgttgca
    10801 ggatccattc gctccatcaa aaactgggtc atgcgcattg actggatttc tttcggatat
    10861 tccaaaccat attcgccatc caagacctca aggacacgat catcccaatt gcctcgaaca
    10921 cttgctgtga taggaaggtc ctttagcagg gcaactaagt catttgcgcc tggaccagga
    10981 agaaaaatat ctcccagaag ccagtattta ctgactcctt gatttttagc atctgcaatc
    11041 actgcttcta gcgccgtcgc attgccatga atatctgata aaattgcgat tttatggttc
    11101 attgtagttt ccttccattt ggtaatctac tctttcttcc gccacttgag gcaagatttc
    11161 tgtttcctgc gggttcaatt ttctttgcac agcctctgca actgctcttg gtaccccaac
    11221 ttcgacaatc tcatccacac tggcttcctt gattttagtc aaagacttga aatgcttcat
    11281 gagattctgc ttgcgtttag gtcccagacc gtcaatccca tccaattgag atgaaaagga
    11341 atttttggag cgcagttggc ggtgaaaggt gatggcaaag cggtgcacct catcttgaat
    11401 gcgttgaagg aggaaaaatt cttgagaatt acgagacaag tccaccactt ccagcggatc
    11461 tccaaagagc aattcatgag tttggtgctt atcattcttt tgcagacctg caattggaat
    11521 atccaagccc agttcctctt ggataacctg cttagcgata ttgacttgac cttgccctcc
    11581 atcaatcaca atcaaatctg gcggagttaa accttctctt tgcactcgac cataacgtct
    11641 gcgaatgact tctctcatac tggcatagtc gtctggtcca accacagtct ttattttata
    11701 cttacgataa tcttttttac ttggtttgcc gttgacaaag accaccatag ctgaaacagg
    11761 actagtcccc atgatattgg aattgtcaaa ggactcgatg cgaactgggg ttgagatttg
    11821 aagcaagcgt cctagatttt caatagctcc ttgggtcttc tcgacagatt tctctagcag
    11881 gttgaacttc tgctctaggc taacacgggc attttttata gctaaattga ccagctgctt
    11941 tttctctcca cgttgaggct taagaatctt ggaatccacc aaagccttga cagcttcttc
    12001 gtcaatatcc tgcggaatca gtacctcatt gggaactaga tgagattttt cttgatagaa
    12061 ttgtcctaca taggtcaaaa aatcctcatc tggatcattg aagtagggga atagattgac
    12121 atcgcgctcg atgagcttgc cctgacgaac aaagaaaact tgcacacaca tccagccctt
    12181 atccacatag tagccaaaga catcgcgatt ttggagatcc ttagccatga cccgttgctt
    12241 ggttcgaagc gttccaatag cctgaatcag gtcacggtat tccgccgcac gttcaaactc
    12301 catagtctgg gccgccgctg ccattttgcc cttgaggtta tcaatgattt tgtcatcctg
    12361 cccttttaaa aagtcagaaa cctcctgagc catagatttg aaatagacct catctttctt
    12421 acagatagta tgggccatgc attggccgat atggtagtaa aaacaaacct tagaaggaag
    12481 attggtacac ttacgaaaag gaaaaatccg atccagtagt cgcttgattt cattggccgc
    12541 cctcacatct ggataaggtc caaagtagag acctccgtcc ttcttgacct gacgagtgat
    12601 aatcaaacga ggatagcgct cattagtgat tttgatgaag ggataggact tatcatcctt
    12661 gagcatgata ttgtatttag gtttattttc cttgatcagg ttgatttcta ggagaagtgc
    12721 ctcaatatta gactcagtaa cgataaattc aaaatctaca atttcagaca ccaaagcctc
    12781 tgttttggta tcatgacttc cacggaaata ggaccgcacg cggttacgca gatttttagc
    12841 ctttcctaca tagataatgg tgccgttttt atccttgtga atgtagcaac cagggctggt
    12901 cggcaagagc tctagttttg gtttaatcaa gttgttcata gttccattat agcaaaaaag
    12961 tagggaaaga tagtacccta ctcactagtc tcatatattt ttcggaggtt tgcaacatcc
    13021 tcttcctgga taccataaaa ggaacctgct ggttgcatga cagacttctc atctgtatgg
    13081 tccaagccaa tcgcatgacc taactcatgt tctgccgtat ggacaaggcg ttcataggaa
    13141 tagccatagt atggattgga caaataataa tgattcaacc gcaccgttac ggacaagaat
    13201 tgccctgtta agagattagt ttgactttct gcctctcctg ccacaggagt gcctccgtcg
    13261 ttcatctccg tagccgtaat atccgcctta ctagactcag tcacgagttc aaagttaaaa
    13321 gcaccaattt gattccagtt ctggattgct tctaaataag cctcttgaaa gcgtgaatcc
    13381 atctggggat ccaggtaaat acgagcagag gcctgtggcc accttccttc agaatgctgg
    13441 tgactatctg tctggcttaa cttaggcagt tgccctgttt tctctcattg gtcaatactt
    13501 tgttgaccaa tttttactga ccgttctgct tgctttagcg ctccttgaaa atccccgttc
    13561 agataccaga gaagtccgaa agcaagcaca cataagagca caactatcca aaacaaacgc
    13621 cacacaaaag aaaagaaagc ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt
    13681 tctagcaaat aagaattatt ttactaaaag aagctaaaag aaatctaaat actgactttt
    13741 tcatcttaac gtcctactat ttttttgagt aactggatag ctttgtattt taaaggcgat
    13801 ggatggtaac ggaaagtacc tgctttgcgt acaatatagc cattaaaatt ctgtttaaaa
    13861 cgcaaaacac catcacttcc atcaaaaatc ccttgaatgc ctaggaagtt gtatttaggt
    13921 attccacgtt ttatgctttc caacataaca tatttttgaa gcagtgcagg ggcatagaac
    13981 ttattaaact cagtgtagga accactaaag agataagtcg tttcctgagg catataaaca
    14041 aataaactcc cagctaaaac aatatcttct tctccatatt tttcaatcaa gtctcgcgct
    14101 tctgcttttc gaacttcaaa cgtttcaaat tgactagaat attctctcag ttgattttgt
    14161 tttttctcag aatgaggatt tttactcaaa tcaagtcgca acttgtccaa gttttcttct
    14221 agtttacttt gttcaccttg caatttgctc atatactccg aaaaatttaa gcttgctatg
    14281 agaaactccg cttgttctcc aaaagtatca taaaaatgct cataatattc taaactttta
    14341 tcactatatt ctctacgttc agaggtttct tttgttatat tcttaaaaat cgatagttct
    14401 tcacgtttta actttttcaa ccgaatgcca aaggtttcag cctttttcac caagggttta
    14461 ccctttttgc taaaactttt aagcaaactc ttttcagtta attcagttaa atctttatag
    14521 tataaccaat ctggttctcc acctgggtaa cctgttgtta agccatcaaa ttgataacct
    14581 aaatcagtca aaccttgaat aatacttttt ttctcagcat ctattggatt accttggcta
    14641 tcaaaagttt gataagtttc ataaggtttt ataagcaact ctaatacacc attttgcttg
    14701 gcatattctt ttaactctgc ataaaaaact ggaagagcat cttgttgggt ataaatcggc
    14761 cccgaattga gttccatatg cagaccaccc agcatgggca agctataaac cagagctgca
    14821 acttgaattt ctccttcttg tttcaaagca agataaacaa ttcgagcccc tcttttttct
    14881 agcaaatccc ccatctggac agattgcata aaggaacgag aagaaacctg atcagaataa
    14941 gtctgaaact cttctttcgt gagtgttgtt agtgccatat acttactttc tatgtttttt
    15001 tcttaatgtt ttacggaaat caagagcaag tcttaacaga ggatagagag gatgagtggg
    15061 cattgtaaat tcacccaagt attcttcaat cgttggatta aaattagctt taaaacgata
    15121 aagtccacca tctaaattat tttcgactcc tcctaaattt tgccataaaa tgccacgttc
    15181 aaaggaatat ctagctgtct cataccaggt caaaataggg gctttatatc gtctaaaatc
    15241 ttcatccatt cctgcatata gattgacaga agtttgtccg aattctaaag tcaaggtagc
    15301 cgctaaagga actctcgctt gacctgcatc tatatattcc tgcaagaagg tcaattcctc
    15361 taacaaacgt tctttttcct tcttctgcgc ttctactttt gaagttcgag tcgattcagt
    15421 aaaggtctct tccaaggctc tgtttttcgc taactgttct tctaattctt gcgaacgttt
    15481 agagacatcc aaggttgcca aggtgatata ggccttgtcc ttaaaattat ctaacaattt
    15541 tttataatag gcttcattcc tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa
    15601 ctccgaaaat gaatctaata gttccagtcc accatattga atctcaagcc ctttgtttcg
    15661 tgctgttcga atagcctgtt ttgttgactt ggaaagttta tcttcttcaa aattttcctt
    15721 gtatattttt gcctgaatac gaggttgaat ggtgtctccc atttcctccg tttttcctga
    15781 ccaccttact cccatttgtt gcaaactatc aataatagcc agattttcag gaaattctgt
    15841 cttttcctga ttgattaaac tttgagatag gcaaatactt gggtcaaaag tcacaaaaac
    15901 cgctctctta ctgcgagcat aggacttaat agactgaatg gcaaaattca agagttcttt
    15961 atccccataa tccaatatag gtcctcttgg gatgtaaaac attttatagc ctagcggaag
    16021 agttctaatc aaaatactag ctgtcgccag taatttttct tccctgtaaa caccaaactt
    16081 ctcatgttgc caattagact taacttcctc ccaagcacta ctttgtaata cattggctaa
    16141 ttcatgttct ttgacaaact gatcatattc taatgtggga atgccaattt gataacggta
    16201 catttcctac tctctttcct ccagtatttt attactattc tactactttc gtttgaaaag
    16261 tctagtgaaa acatatttta ttttagttct actcccccta tgctgaagtt caaactaagt
    16321 cagtctctct tctaatttga aatcaattgg tagggttgtt aaaaaacctt ccaattgttt
    16381 ttcccaataa taccactcgt gagttccagc gctatggcta taggtcacat caaaacctag
    16441 ttttttgaga tttttcactg cgagattatt ggcttcgtac aagaaatcct gttcgccaca
    16501 ccacgcccaa agtttggtct ttttatccga ttttttagcc agactttcaa gagaataggg
    16561 actagttgtc cagtctttaa tctctccaaa aacacctctc cagtatgctg gcgttcccag
    16621 attttgactc tcaggagaaa aatcttgaaa gctcaatgca cctgaaaagc tagctgcatg
    16681 agaaaaacga tttgtcgtaa gagccagttt gaagcagccg tagcctccca tagaaagacc
    16741 agcgataaag gtcttttcac gcttgctagt cacattaggg aagaagcgtt tcagaacctg
    16801 tggcaattcc tctgctagag ccgtgtagta gtcaaaacca tactgggtat cggtgtacca
    16861 accattgctg gtattgggca taacaacgat gagattagtt cctcgaagca agcgttctac
    16921 attggtccgc ttaagccaac tattatgatt tccagacatc ccgtgcaaaa ggtacaagac
    16981 gggaatatct tcacactctg gttcttccac tcgattggca tcagggtaga ggacattcac
    17041 cccccactcc atatccaata cttgtgagta atactcgatt ttcattactg ccatgatttt
    17101 ctccttctat ttttctataa gaaaaagccg aaactcgact ttctctctgt ttatttcaac
    17161 gattattttg cttccatgac tactggtaaa atggctgggc gacgcttggt ttgatcaaag
    17221 aggtacttgg tcagattgtc acgaacctta cctttgagat ctgcccagtc aaagtcatct
    17281 ccttgaagat actcttctac cgtttggtta atcaattctg aactttcacg gagaatatcg
    17341 cgactcttct tgagataaac aaatccacgc gtgtgaacac gagccctagc cacaattttc
    17401 ttctcacgac ggttgactgt aatagccacg atgaaaattc catcctctga caagacctta
    17461 cggtcacgaa gaacaacatt tccaacatca ccaatggcat tcccatcaat caagatatct
    17521 cctgctgaaa ccgatccagc tggaacaaag tctccattct cgtaagccat agtcgtcccc
    17581 tttttaggaa tgaagatgcg ttctggcaac atcccaactg ccatggcagc cttagcgtga
    17641 gcatccaact cacgatactc cccttggaca gggaagaggt acttaggttg caaaagattg
    17701 atcatcagct gcaaatcacg cacatttccg tgccctgata catgtaaact ttgggtaatc
    17761 aatttgacaa ccccacctgc ctgataaatc atattttcca cacgcgcaac aaaggcttct
    17821 ttagcaatag acggagccgt agcaatatag accaggtccc catccttgat ttctacataa
    17881 cgatggcgac caatcgacat cttacgaagt ccattgatag gctcacccat acgacctgtc
    17941 tcaagaataa tcaactcatg gtcttcaaag cgagacatat ctttaggctt aatcaaaaga
    18001 atttcgttgg ctaaagacaa cttcttaaga cgaatcgctg tgcggacgat attttcaata
    18061 tcaaatcctg tcaagacgat acgtcgacct gttttatccg cagcgtcaaa aatctgctga
    18121 atacgagaaa gattactgga aacagctgca acgatgatac gaccttccca gtcagcaata
    18181 gtttgggtaa tttcatccct aacttcactt tcactagcca cctgaatatt gctgtctgca
    18241 ttggccgaat cactgaggag agccaggacg ccgtcacgac caatctctgc caaacgagca
    18301 aaatcagttg cataagattc actagccgtt tggtcaaatt tgaagtcacc tgtataaacg
    18361 atgcttcctt ccgatgtctt caagacaatt cccagactct ctggaacgga gtaagtcgta
    18421 gggaagaagg aaaccactgt cccaccaaaa tcaatctccg tattctcatc aatgacatgg
    18481 aaatcattaa atttcttaac ggcatcattt cctttgacaa agagctttgc caactcaatg
    18541 gtcaactcag acccaaatac aggaacttta gcctctgcca agagataagg tagagcacca
    18601 atggcatccg catgcccgtg ggtcaagaaa accccagcaa tacggtcgct attttcaaaa
    18661 aggtaatcca tgtttggaat caccacatcg acccctaatt gttcattttc aggatatttt
    18721 aaccctacat tcaaaacaaa aatggactct ccaatttcag caatgtacat attttttcca
    18781 ttctcacgca caccaccaag tgttgttaaa ctgatattac tcatttttcc tccaaaatct
    18841 tagtttatct tgattatagg gcaactctac cctcttattc taaaagttct aatactttca
    18901 gccgaatctt ttcctaccat tataccattt ttttgatgat tttcaaaatg aaggtctgtt
    18961 ttcaaaaaag agttgatttc ccaactcttt cctaacttct actctttttc catcaaaaaa
    19021 tcataaattt cttgcaccgt acccagcgcc atcatttctt ggtctttaac ggtttgtttg
    19081 agattttggt aaatatgact ttctcctatc tcccgctttg gcgcctcttt attgactgtc
    19141 atcacaccat cttttatcgt cacaaagcct agttcttcaa atacttgaat catcttgacc
    19201 agcaagattt gttgaatatt aagatatgca gccaaatctt tcagcttgta gcgaatatca
    19261 aactctggga accggtaaat agtcttgtac aatttggcaa actgatctct agtcccataa
    19321 cctgtcagat aataggcctt gtcaatatca tttttgaaat agacagcaga gaaatactgt
    19381 tcctgaaaaa tggtcttcag ctgagtaata tcctctggaa tgttttttac gacaacagct
    19441 tcactagccg caagatttgg cagttctcca ggaaaatcca agactggaac accttctggc
    19501 aagactgcat tttttccacg aatattaaaa agttgaacac cttccactcg cgcatccacc
    19561 atcatcaact ggagggcagt ttggccattc cattggttga cagacaattt aaccgctaac
    19621 tctagattct tggtttgaga aaactctgtc gcccatctgc cttgaccaaa ggctaccact
    19681 tcaaaactcg cctcaccctt ggaaattttc agctttagat gggcattacc tgcccccata
    19741 gtacgagcac tttcgacctg aaaattcttg atataaaaaa taggtttctg attatccatt
    19801 ccaaaaggag ctaaacgttc aaaacttttg accgtttcca agctaagtgc ctccaaatcc
    19861 aactcttcat ctaggtttaa cttattcttg ccaccagcat ctgcaccttt ttcacgaaca
    19921 taatcttcca aaatctgaga taaatctgag agttgctcaa cttccagcgt catacccgct
    19981 gcacctgcat gacctccaaa ggcgatgaag aggtctcgat agggatccag agcttcaaaa
    20041 atatcgaccg cttccacact acgagcactg cccttggcac gaccgtcttc tatattaaga
    20101 acaatgactg tctgtcccaa ttcttccaat aaacgaccag ccacgattcc tagaacccca
    20161 ggattccagc cttccttggc caagacctga accttcttct caggatccac catggtcttg
    20221 gcttcttcat agatagactg aacgatttcc ttgcgctctt cgtttttctg gtgaatcata
    20281 agggcaatct catgcgcttc ctcatcatca aatccagtca acaaatcaat ggcaggatta
    20341 ggatcatcca agcggcccaa ggcattcaaa cgaggagcaa tctggaaacc aaccatttct
    20401 tctgttactt cgttggcagc aatcccagcc atgtctagca tttcttgtag accaatacgc
    20461 tgagtgtggc ccaacatttc cagaccatat tgcaccaaaa tgcgattttc atccgtcaga
    20521 ctcaccatat cagcaattgt accaatagcg accaaatcaa gcaattccac ttgcacttct
    20581 tctaacaggg cacaagccaa cttgaaagca actccacaac cagccaaata tttaaaagga
    20641 taatccgcat ctggatgttc aggatggaca atagcataag catctggcag ggtttcaggc
    20701 atggaatgat ggtctgtcac aatgacatct actcccatag actgagccaa tgcaatagcc
    20761 tcatgaccag caaccccatt gtccaccgtc acaatcaagg aaattccttc ttgctcgata
    20821 aagtatttat aaacactagc attagggcca tagccatcgg taaaacgatt tggcaggtaa
    20881 actcggcact cagcaccaag ttgttccaaa ctttccttca caatagaagc cgaagtcatg
    20941 ccatccgcat catagtctcc ataaacgaga atattttccc cttcttcaat agcctgacga
    21001 atccgctcca ctgccttgtc catatcatgg agcagataag catcatgtaa gtcctccaag
    21061 gaaggttcta aaaacttctt cagactttct tggtcctgaa tccctctctc aaacaataac
    21121 cgagccacct caggacccag tccagccttc ttggctatct ttgtaaaatc cgcatcttct
    21181 acctgcaggg caaactgcca ttcataagta ggtgttatca aaaagacatc cactctttct
    21241 aagaattcta ttgcttcatt ataacatgat ttagacgttt tctctatcca gattgctttt
    21301 ttataacatt ttatagtata ttgaaactag aatagtacac ctctacttct aaaatattgt
    21361 tagaaatcga tttgactgtc ccgatcgatt tgtcctgttc ttatctcact atagtgattt
    21421 tttcagatat ggtttgacaa gaacattctt ttattgtaga attgtgttat aaaatctaac
    21481 ataaaggaga tctctcatgg ctttagtaga atttaaaaac gtcgaaaaat attacggaga
    21541 ctaccacgca ctccgcaaca tcaatctccg ttttgaaaaa ggacaagttg ttgtcctgct
    21601 tggaccttct ggctctggga agtccactct tatccgtacg atcaatggtt tagaggctgt
    21661 tgacaaagga agtctcctag tcaatgggca ccaagttgct ggtgccagcc agaaagattt
    21721 ggtacctctt cgcaaggaag tcggcatggt ttttcaacat tttaaccttt atccacacaa
    21781 aactgtgtta gaaaacgtga cacttgcgcc cattaaagtt ctaggaattg ataaaaaaga
    21841 agctgaaaaa accgcccaaa aatatctgga atttgtaaat atgtgggaca agaaagattc
    21901 ctatcccgcc atgctatctg gtggacaaaa acagcggatc gccatcgctc gtggtcttgc
    21961 tatgcatacg gaactcctcc tctttgatga accaacatct gctcttgatc ctgagactat
    22021 cggagatgtt ctagcagtta tgcagaaact ggcgcatgat gggatgaaca tgatcatcgt
    22081 tacccacgaa atgggctttg ctcgagaggt tgcggaccgc attatcttta tggccgacgg
    22141 agaagtttta gtagatacga cagatctggt tgtcggtgtc aaacaagacg ttcccaattt
    22201 tggttacaaa gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat
    22261 ggtagctgat gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg
    22321 cccccttcta gacaatgaac aggtcgatat ggatatcgcg acctttacca tcacggacga
    22381 acgcaaaaaa ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt
    22441 caataaatct gccaaaatca aaaagattga gaacctaaac ggcaaaacca tcggagtcgc
    22501 ccaaggttct atcacccaac gcctgattac tgaactgggt aaaaagaaag gtctgaagtt
    22561 taaattcgtc gaacttggtt cctacccaga attgattact tcccttcacg ctcatcgtat
    22621 cgatgccttt tccgttgacc gctctattct atctggctac actagtaaac ggacagcact
    22681 actagatgat agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga
    22741 gctcaacgac tatcttgata acttggttac taaatggagc aaggatggta gtttgcagaa
    22801 actttatgac cgttacaagc tcaaaccatc tagtcatacc gcagattaag gaggataccc
    22861 tatgacagat ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg
    22921 tttcctcttt actctcgccc tagcgattgg atcctttatc ctcgccatgg tcttaggaat
    22981 cttctttggt gccatgtcaa ccagtaaacg tccgattttg cgaatcttag ctcgcatctt
    23041 cgtggaattt taccaaaaca ctcccctctt ggtgcagttt gttattgttt tttatagcct
    23101 acctcttatc agtgaccata ctatcatgat tccgatttat tggacagctg ttctctgcgt
    23161 gggactctat cacggcgctt ataccgctga ggttattcgt tcagggattc agtctattcc
    23221 tagtggtcag atggaggtcg ccttgtcgca aggttttacc tatatcagtg ccatgcgctt
    23281 gattatcttg cctcaggcct tccgcatcat tctccctcca ttgaccaacc aaattgttaa
    23341 cctcatcaag aacacctcta ctgtagctat catctctgga gtagacttga tgtttgtgac
    23401 taagtcttgg tcggctctca acggaaacta tatcccagcc tttttaggtg ttgctcttct
    23461 ctactttgcc ctatgcttcc ctgttgccca gtttggtcgc aagatggagc aagccaacaa
    23521 aaaagcctat tcactttagg aggttactat ggaatctatt ttagaagttt taagcccaga
    23581 taacctagtc tttatcttta aaggatttgg cttgaccctc tatatttctc tgattgccat
    23641 catcctctct actatcatcg gtaccgtgct tgccgtcatg cgaaatggaa aaaatcctat
    23701 cttacgcatt atttccagta tttatatcga gtttgtgcgc aacgttccca accttctctg
    23761 gatttttact atctttttgg tgttcaaaat gaaatccacg ccagcaggta ttacagcctt
    23821 tactctcttt acatcagcag ccttggctga gattattcga ggcggtctca atgccgtaga
    23881 caagggacaa tacgaagcag ggatgtcaca aggcttcacc tcagcccaaa tcctctacta
    23941 catcattctc ccacaagcca tccgcaaaat gctgccagcc atcatttctc agtttgtaac
    24001 cgtgattaag gacaccagtc ttctctactc tgttatcgcc ctacaagaac tctttggagc
    24061 cagccaaatt ctcatgggtc gttatttcga accagagcag gtcttcagtc tttatatcct
    24121 gattgccctc atctacttca gctttaacct agccatttcg agcctgtctc atatgctagc
    24181 aaaacgttgg caacaagctg cagaataata ctcttcgaaa atctcttcaa accacgtcag
    24241 cttcaccttg ccgtatatat gttactgact tcgtcagttc tatccacaac ctcaaaacgg
    24301 tttttgagca gcctgcgggc tagcttccta gtttgctctt tgattttcat tgagtataaa
    24361 cagccactct ccagttcaat tggagagttt tttataagaa cagagattta cacacctaga
    24421 tttgacacca tacattttct atgataaaat gtaacaaatt tatttacaac aaatcgaaat
    24481 ctaaatgaaa tggaattttc tatgaaatca atcaaaggac tactctttat catagctagt
    24541 tttatcttga ctcttttgac ttggatgaac acttctcccc aattcatgat tccaggacta
    24601 gctttaacaa gcctatctct gacttttatc ctagccactc gtctcccact actagaaagc
    24661 tggtttcacg gtttggagaa ggtctacacc gcccacaaat tcacagcctt tctctccatc
    24721 atcctactaa tctttcataa ctttagtatg ggcggtttgt ggggctctcg cttagctgct
    24781 cagtttggca accttgccat ctatatcttt gtcagtatca tccttgtcgc ctatttaggc
    24841 aaatacatcc aatacgaagc ttggcgatgg atccaccgca tggtttacct agcctatatt
    24901 tttggactct ttcatgtcta catgatgatg ggcaatcgtc tccttacatt taatcttcta
    24961 agttttcttg ttggtagctc tgccctttta ggcttactag ctggttttta tatcattttt
    25021 ctatatcaaa agatttcctt cccctatcta gggaaaatta cccatctcaa acgcttaaat
    25081 cacgatacta gagaaattca aatccatctt agcagacctt tcaactatca agcaggacaa
    25141 tttgccttcc taaagatttt ccaagaaggc tttgaaagcg ccccacatcc cttttctatc
    25201 tcaggcggtc acggccaaac tctttacttt actgttaaaa attcaggtga ccataccaag
    25261 aatatctatg acaatcttca agtcggcagc aaagtaaccc tagacagagc ttacggacac
    25321 atgatcatag aagaaggacg agaaaatcag gtttggattg ctggaggtat tgggatcacc
    25381 cccttcatct cttacatccg tgaacatcct attttagata aacaggttca cttctactat
    25441 aacttccgtg gagatgaaaa tgcagtctac ctagatttac tccgtaacta tgctcagaaa
    25501 aatcctaatt ttgaactcca tctaatcgac agtacgaaag acggctatct taattttgaa
    25561 caaaaagaag tgcccgaaca tgcaaccgtc tatatgtgtg gtcctatttc tatgatgaag
    25621 gcacttgcca aacagattaa gaaacaaaat ccaaaaacag agcttattta cgaaggattc
    25681 aagttcaaat aagtactcat actctcctgg gaattctagg agagtttttt atagccaaat
    25741 gaaataagtc cggaacgatg gaattttggc attcaaatca attgataaga atgttttata
    25801 gtggagtgaa ataggatacg aacaaattga ttaggaaaat caaatgaatt tatagaaatc
    25861 ttttagcagt tatgttgtcc tattctcgtt tcaaaacgct atagaagcag cattgtacta
    25921 gtctagattc agtttactat actaaaacga gtagcttgaa atcaaaaaac ccaccctcac
    25981 aggcaggttt tatctgtatt attcagctag attatgcttt accttctgaa ccgaatacgt
    26041 cgatacgttc ttcaaccgat gcttggatag cttttacacc gtcagccaag aattttcgtg
    26101 ggtcgaagag ttttttcttg tcgtattctg cttcgtttgc ttcgtagtca cgagcaaatt
    26161 tacgagttgc gttagcgaat gcgatttggc attctgtgtt aacgttaact ttggcaacac
    26221 caagtttgat agctgcttgg atttgctcat caggaatacc tgatccaccg tgcaatacga
    26281 ttgggaatcc tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca agaccttccc
    26341 agtttactgg gtaagggccg tggatgttac cgataccagc tgccaagaag tcgataccag
    26401 tttcaaccat tgctttagcg tcttcgattg gagccaattc acctttaccg atgattccgt
    26461 cttcttcacc accgatagta ccaacttcag cttctactga gataccttta gcgtgtgctt
    26521 tttcaacaac ttctttagcc aatttaaggt tttcttcaac tggaaggtgt gaaccgtcaa
    26581 acatgattga agtataacca acttcgatac actcaagtgc atcttcgtag tgaccgtggt
    26641 caaggtggat agctaccggt acagtgatac ccattgattc aacaaggtta gcgatcaagt
    26701 tgcgagcaac tttataacca cccatgtatt tagcagcacc cattgaagtt tggatcaaaa
    26761 ctggagcttt tttagcttct gctgcgcgca agatagcttg agtccactca aggttgtttg
    26821 tgttaaatcc accaactgca taaccgttgt cacgggctgc ttggacaaat ttttctgctg
    26881 aaacgattgc cattttatca ggcctcctgt atatttttat gggtcatccc atttacattg
    26941 ttcattttat cactttttgc caaaaaaatc tagtttttcc cgcagtttcg attgattttc
    27001 ttctaactcc atctatgtaa accctttctc tccctagtct tgggcgactt ttggaaaagc
    27061 tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt tttcatgttc
    27121 taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc gactagcatt
    27181 gccagaaaaa aactgggcta gtttttcttg ttcctctgag ctacagctat tttcgataaa
    27241 aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt gcttaatggc
    27301 attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat aagcctgctg
    27361 atgggtcaaa ctattgtcta tctggagctc tctttccttg gctagcaagg cataatcttt
    27421 gaccagattt ttcgtcatct ggaggaggtc aattgtttcc ctatcatctc gcaattcctg
    27481 cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca caatccccaa
    27541 ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc tcatattttc
    27601 gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc ctcgtaggaa
    27661 ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca agtccgcaat
    27721 aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac ctatctcatc
    27781 cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac gggtcacccg
    27841 cttgatttcc aaaatcggtg caacaatagt ccgagcgtag atgtaggcca ccaagaggga
    27901 aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt gctccgcttc
    27961 cttttgtaaa tccatggaag ctagaaactg gagaatcata gtaccaccgt cttgcgtttt
    28021 cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca gaggaagact
    28081 gtccttgact tctaacttgt cctcggtcat ctcacctttg acggtcccct tgatatcact
    28141 agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc cttctaggga
    28201 ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca gataagtcga
    28261 aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa atatcgagaa
    28321 agtatatata aatatctttg taaataaacc tgttcgtttc attttcgctc caatttataa
    28381 ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa ttccttgata
    28441 taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac ggcatcgata
    28501 atctgagacc gagtcaaggc ccggccttca tttttcacta gatagtccag aatttccaac
    28561 tctttggcat tgataggcac ttcttgacct gcgaggcttg cactgtagct ttcaaagtcc
    28621 accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt gaaaatcgcg
    28681 tccaccctca cttttaagag ggagagggag aaaggttttt ccagatagcc atctgccaaa
    28741 gaggcaaagg cactcatctt gtattcctca tcctgaaaag ctgtcaacat caagacagga
    28801 acctgactgg ttttacgaat ctcagctagg acttctaggc cgttaagctt gggcatctgg
    28861 atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc ttcctgaccg
    28921 tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac cccctcacgg
    28981 atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc tattttttat
    29041 ttttcttaga ataaatacct actctatttt ctattatagt ctcttgctgg ccttttgtct
    29101 gtaagcaact gaccactaga taaaacgttg tgaaattcct ttctcataaa tttcatatat
    29161 ttagtatatt atatttaagc actaaagtac aaagaaaaca actgaaagca atgattttca
    29221 ccactgcttt ctgcttcatt tatcatttta aaactttcag ttgctagcct catttttcac
    29281 tctggcatcg gtattattca ccatccagca agagttcttt tggttgtttt ctaaggagat
    29341 tacttgaagc aagcgccata acggccacca ctagaaccaa ggcaaggaca aagacgatga
    29401 taaaatctga tgtctgaata gaaatgtcta ggctcgataa ggtcttacta aagccatcta
    29461 cttctgcacc gccaccaagg ttagaggctt gaaccgcctt actagcctgt ttggcaacac
    29521 ctgaagtcac attggcaagg acagtgtttc caattgcacg ggcagtgtaa ttagctagga
    29581 agtaagcaga aactagagca gggatagcaa tcaagataga ttcggtgatg aattgaccca
    29641 agatacttgc ctgcttgagg ccgatagaga ggagaattcc cacttccttg cgacgggcgt
    29701 tgatccaaag gctgagcaag agggcaagga ggagaactga gaagctcaag ctaccccaga
    29761 agaggaggtt ggccatcttg tacataccag agatagattg ctcaagagct gggtagttag
    29821 aggagctctt gacaagtgtg tagctcttcc agttgatacc actgatgcca ttcaactctt
    29881 tcataacatc atccaagttc ttgtctgctg ttacaaagaa ggttgcgtcc ccataaatgg
    29941 ctgtgtcttc tgtgtatcca taaagttttg cagcagtgtc aatgtctgta atagctgtgt
    30001 tttcgtaaag ttcttgtgag taggttactg ctgacttatt atgaccatca aagagtccct
    30061 tgattgtcac ttcaactgtt tccttggctc ctttttcatt atctgcatcg tagatattag
    30121 agtccagttt aaccttgtcc cctactttcc agccgtgttt ggctgccaag tccttgtgca
    30181 agaggatttt atccttgtcg tcgttggtta agtgctctcc ttcgactagt ttataagaac
    30241 cagagacaaa cttgtcttct ttaaaggagt cattgacacc tgtaatcatc aagctacttc
    30301 caaaacgttt ggcacgatca gcagtgagat tcttcttggt ttctggcgtt tcaatcaggt
    30361 catatccagt caaatctccg atagcgttga tacgtttgac ataagactcg atggccttgt
    30421 tttcggtgat ttttttgatg tcttcaccct tgatattccc agcaccacga ggcgttcctt
    30481 ggttgacgcg acgattgatt tgcatggaga agctattggt gatattttta aaggtctcct
    30541 gagaagcctt ggcagtagct cccttgattg acaagccgac caaactcaag ctcgccatga
    30601 ggagaataat caggaagatg acaatcgatt taaaaaactt ccttgtaaca taggcaaatg
    30661 cgttgtgtaa catagattcc ctttctagat tttgttttaa tcattctatc aaaataagct
    30721 caaattattt actagtattg cgcgtttcag tcagtttctt atcctttaat tcaagtgtaa
    30781 tatctgacgc ttgtgccact tctttactgt gagttacgac aatcacacat ttacctgttt
    30841 tctgggcaag tgatttgagc agttcgacaa tatctccagc agttttagga tccagatttc
    30901 ctgttggctc atcagcgaga ataactggag cttctgatac taaactacga gcaatggcaa
    30961 cacgttgttg ttgaccacct gacaactgga gaacattccg cttgatctga ctttcatcca
    31021 aaccaagctc aagaagtgta tccttgctgg cctttttgtt aaccaagcgg atattttcca
    31081 gtggagaaag ataatctatc aagttataat tttgaaagac caaggaaata tggtgcatgc
    31141 gatggtaaga atagcccttc ttacgaatat cctctccttg aaaaaggata gaaccttcaa
    31201 caggactatc tagaccagca agtagggaca agagagtgga ttttcctgct cctgactccc
    31261 caataatact gtaaaatttc ccgggttcaa aattataatt gatctgatat aggactgctt
    31321 cagcagtgtt cttataacgg taggtaaggt cttgtaattg taataaagtc atgatttctc
    31381 cttcttatac tcaatgaaaa tcaaagttca aactaggaag ctagctgcag gttgctcaaa
    31441 gcacagcttt gaggttgcag atacagctaa cgcggtttga agagattttc gaagagtatt
    31501 aactaataga tgataaaatt tctttaggcg attttctaaa taagaatagg aaacaaagtg
    31561 ctacagacaa gcaactaagc agaactagaa agacatagga ttctgcaaat gataggatat
    31621 tagttgatag actgcttgct ttagctagcg tgtcttgtaa gcttgcctgc tctccacttg
    31681 ctagtagagt ttggagtagg taagatgtga ttgcgtttcc tacaacaaat gctggaagca
    31741 aagcgccgag agataccaaa actacctcta aacagaattg taggaagatt gaggtcttgc
    31801 cttttccaag tgccagtaaa atccccactt cgtagaccct ttctctcaac cagagagaca
    31861 aaacaagaat taaggcccct gctcctgcta tcaacatccc ataaaggaag atggtcagaa
    31921 aggtttggaa ggttgcaact gagtctttga tttgttcaaa agccttgttt tccttttcga
    31981 cttggtagcc ttgattttcc aaggccaagt tttctacctg cttcacgagt ccgtccattt
    32041 ccttaggatt ttctacatag aagcgcgctg cactgacttg cggttcacta tttcccaaaa
    32101 gagtttggct actgtcatag tctgtaaaga cttgattttc actgaagtca gaagacaagc
    32161 ctgtgaattt ctcctgtttt ttaccagaaa agatgccgac aatttcaaac tcaactgttt
    32221 gtcctttacc agcttcggac tgaccagcat ctaaggcaat cttgccatga agcgaaagac
    32281 cattcttctt agccaactct tcgtggatga gaattttctt tgaatcccct ttttgaagat
    32341 gtctcccttc ttttagattg aaagccgaac tggtaaaggt cacatccttg gatgaatcct
    32401 ccagagctgt taagctaacc aagttcttgt ccgcagctga caaatcatca cgttcaacgc
    32461 tctgctcgcc actcactgct tccttgtctt ttagttttgc gaccgtctcc agttcaggag
    32521 aaacattttc cagtccctta atcttgctta cagatgctag gtctgacaac ttgaatgtct
    32581 gaccattttc tatcttctta attgaaaaag aggtattgag tgatttgtaa agattggttt
    32641 ccactgtttt gttggacttc atcagagtca aacaggctga gattccggcc aataggacca
    32701 ataaaatcag aaataaaata aaacttctca gtcgttttct gctgacataa gcccaagatc
    32761 tttggattgg attcatttgt cacctccata tttgtaagac tattataaaa cccaaatatg
    32821 aaatgtttat gaaatacgaa aaaaaaaata tcaaaaagag caacggcttt caccgttgct
    32881 ctttcaatca ctattctagc tagtttccga ctagtttaag cttgacttat cttaactgag
    32941 ccagaatagc tttgagtttc tcaatcaact catcttctgt gtgatcagac tctttctcat
    33001 tggctaggaa aggaactgct tgagcgagag cttctcgtgc ttggtcgagg agtttcgaat
    33061 ctacacttgt aaggtcgctt tcttgcagaa ccttagtcaa tcccttggtc aatttcttga
    33121 gttctgactc tttcttacga cgcgcgatga ggaagagaag gagaccaaga aaggcaagca
    33181 ggctagcaat catcgtacca tatggaagat gaccttgctc tttgcttgtt tcttgcattt
    33241 cctcttcatc cttagtcgct tgcttgcctt tcaaggattc gagtgcttct ttgaccttag
    33301 cagtaatctc tctcaagcct gcctctgtca agtcagtatt tctaagggct acttgactct
    33361 ctacgagaat gatcttagca gcatcgatga cagattgatc aataccatcc aagtttttca
    33421 agcgagtttc caattcttca accaatcgag caagttcaaa cttgtcaaca ggacgagcct
    33481 cactaggagt tgctgtattg cttgaattat ttggagtgct tggagaaact ggtgtttctt
    33541 gagctggagt acttgcttga gcctgtcctc caacagtaga cgatggagta gcagaggtcg
    33601 tgttcctact atcgtcggtc gtcacattag gcgctggagt gttggcactg ttatctggtg
    33661 tcacactgtt actattgcta tcagcagggg tggtagtacc accgttgttg gtgttagcac
    33721 tattgttagt gttgccactg ttgccatcct tacttggtac agaagttggc ttatctac
//
LOCUS       DAVFJR010000020        32566 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVFJR010000020 DAVFJR010000000
VERSION     DAVFJR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.021"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VU722_001193"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VU722_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU1772174.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLVGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VU722_001194"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VU722_001194"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU1772175.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VU722_001195"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VU722_001195"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU1772176.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VU722_001196"
     CDS             complement(3790..5058)
                     /locus_tag="VU722_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU1772177.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLLQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AANKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VU722_001197"
     CDS             complement(5178..5546)
                     /locus_tag="VU722_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU1772178.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VU722_001198"
     CDS             complement(5539..5805)
                     /locus_tag="VU722_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU1772179.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VU722_001199"
     CDS             complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VU722_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU1772180.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTNTRTKGNAELILLIDAYLPDTYIS
                     DQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQ
                     RVERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDY
                     EILEGLLIFGESLLEIKESKEKNSI"
     gene            complement(9379..9948)
                     /locus_tag="VU722_001200"
     CDS             complement(9379..9948)
                     /locus_tag="VU722_001200"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU1772181.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VU722_001201"
     CDS             complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VU722_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU1772182.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11254..12267)
                     /locus_tag="VU722_001202"
     CDS             complement(11254..12267)
                     /locus_tag="VU722_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU1772183.1"
                     /translation="MDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKF
                     KIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYA
                     VSLQAIPFNPARDIIVPRRKEKKGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLY
                     KTLLATGLRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKT
                     VLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFH
                     AFRHTHASILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKL
                     KSS"
     gene            complement(12268..12420)
                     /locus_tag="VU722_001203"
     CDS             complement(12268..12420)
                     /locus_tag="VU722_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEU1772184.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQA"
     gene            complement(12516..12968)
                     /locus_tag="VU722_001204"
     CDS             complement(12516..12968)
                     /locus_tag="VU722_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU1772185.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(12968..13972)
                     /locus_tag="VU722_001205"
     CDS             complement(12968..13972)
                     /locus_tag="VU722_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU1772186.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14121..15077)
                     /locus_tag="VU722_001206"
     CDS             complement(14121..15077)
                     /locus_tag="VU722_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772187.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15192..15425
                     /locus_tag="VU722_001207"
     CDS             15192..15425
                     /locus_tag="VU722_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772188.1"
                     /translation="MEQWTLKACRVNAGYTLRQIAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKREVQ"
     gene            15515..16120
                     /locus_tag="VU722_001208"
                     /pseudo
     CDS             15515..16120
                     /locus_tag="VU722_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518114.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            16132..16392
                     /locus_tag="VU722_001209"
     CDS             16132..16392
                     /locus_tag="VU722_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772189.1"
                     /translation="MENEFKTVTNAKGLEIPKYPKDFKKLVEMDRQLAEYLCMNYENL
                     DNEDLGAFLETVEQGFSWILDLIESKDLLYSPQTGKKARKRQ"
     gene            16621..16791
                     /locus_tag="VU722_001210"
     CDS             16621..16791
                     /locus_tag="VU722_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772190.1"
                     /translation="MGKTLGRPKSDNPKNKQLKIKMTEQDFNNLEELAKKKNMTKTDI
                     VMRGIELVKSEP"
     gene            16946..17401
                     /locus_tag="VU722_001211"
     CDS             16946..17401
                     /locus_tag="VU722_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772191.1"
                     /translation="MRKKHQVVKFKDIAEKLPELEGKRLEEITKVLGYRNLESCRTNL
                     CKLKQNNRLDFTLEKGVYSKFALLDGTVKEELEDKELSERGRYLKSVDRYKAMLNAFS
                     IAFDSTVKAETRQKAEHDGLKALDRIPDKHYALLYDMMEGEDGSKNPLR"
     gene            17376..17525
                     /locus_tag="VU722_001212"
     CDS             17376..17525
                     /locus_tag="VU722_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772192.1"
                     /translation="MEAKTHFARFMRRGMELARQLHSKEIQRDEFDRAWKRLGDQIEN
                     ETKKN"
     gene            17959..18459
                     /locus_tag="VU722_001213"
     CDS             17959..18459
                     /locus_tag="VU722_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772193.1"
                     /translation="MISDKLEAISTNLEEIQKSLVGAETVLAKREISRVLNDLDDVYS
                     ELTSTEYHEQQQTIKEQTEKMKQRGIAEVIGELEEREESYYRNFWGDTQFIRLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWEVIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            18471..18671
                     /locus_tag="VU722_001214"
     CDS             18471..18671
                     /locus_tag="VU722_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772194.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNLLQLITDFLDRKVTPEEV
                     DDLLNMERAEQVEYIKNYQARA"
     gene            18673..18888
                     /locus_tag="VU722_001215"
     CDS             18673..18888
                     /locus_tag="VU722_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772195.1"
                     /translation="MNELDISNTHAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVRVSGGME"
     gene            18885..19178
                     /locus_tag="VU722_001216"
     CDS             18885..19178
                     /locus_tag="VU722_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772196.1"
                     /translation="MSYTMNLYPDIEKIPDEPYFTKDIFLATCMDNATKLAVTMSLLT
                     EQTLDLETETAILKTLDTIIETQKDILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            19159..19500
                     /locus_tag="VU722_001217"
     CDS             19159..19500
                     /locus_tag="VU722_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU1772197.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            19493..19768
                     /locus_tag="VU722_001218"
     CDS             19493..19768
                     /locus_tag="VU722_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772198.1"
                     /translation="MFSLSRESEHDLTHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            20180..20590
                     /locus_tag="VU722_001219"
     CDS             20180..20590
                     /locus_tag="VU722_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU1772199.1"
                     /translation="MEAVSSALFGYSYILYPTIKQGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNLINVLKLKEYTLQRIERLTEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            20747..21139
                     /locus_tag="VU722_001220"
     CDS             20747..21139
                     /locus_tag="VU722_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1772200.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     DQWNLTSKHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            21193..21339
                     /locus_tag="VU722_001221"
     CDS             21193..21339
                     /locus_tag="VU722_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772201.1"
                     /translation="MIEDFLIDLDNIQLEDMEIDFNMDIDIDLNIDFDLDGLDLTLLQ
                     ELEA"
     gene            complement(21770..21964)
                     /locus_tag="VU722_001222"
     CDS             complement(21770..21964)
                     /locus_tag="VU722_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU1772202.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFDRKMNKIID"
     gene            complement(22029..23165)
                     /gene="dnaN"
                     /locus_tag="VU722_001223"
     CDS             complement(22029..23165)
                     /gene="dnaN"
                     /locus_tag="VU722_001223"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU1772203.1"
                     /translation="MMHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(23324..24685)
                     /gene="dnaA"
                     /locus_tag="VU722_001224"
     CDS             complement(23324..24685)
                     /gene="dnaA"
                     /locus_tag="VU722_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU1772204.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(24898..25656)
                     /locus_tag="VU722_001225"
     CDS             complement(24898..25656)
                     /locus_tag="VU722_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU1772205.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIHNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(25714..26895)
                     /locus_tag="VU722_001226"
     CDS             complement(25714..26895)
                     /locus_tag="VU722_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU1772206.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGEIAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLDKSSGDLE
                     S"
     gene            27078..27557
                     /gene="rlmH"
                     /locus_tag="VU722_001227"
     CDS             27078..27557
                     /gene="rlmH"
                     /locus_tag="VU722_001227"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU1772207.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     FTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            27601..27674
                     /locus_tag="VU722_001228"
     tRNA            27601..27674
                     /locus_tag="VU722_001228"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27635..27637,aa:Arg,seq:tct)
     gene            27839..27964
                     /gene="comC"
                     /locus_tag="VU722_001229"
     CDS             27839..27964
                     /gene="comC"
                     /locus_tag="VU722_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU1772208.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            27985..29310
                     /locus_tag="VU722_001230"
     CDS             27985..29310
                     /locus_tag="VU722_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1772209.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            29307..30059
                     /locus_tag="VU722_001231"
     CDS             29307..30059
                     /locus_tag="VU722_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772210.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            30111..30182
                     /locus_tag="VU722_001232"
     tRNA            30111..30182
                     /locus_tag="VU722_001232"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30144..30146,aa:Glu,seq:ttc)
     gene            30188..30261
                     /locus_tag="VU722_001233"
     tRNA            30188..30261
                     /locus_tag="VU722_001233"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30222..30224,aa:Asn,seq:gtt)
     gene            complement(30302..30844)
                     /locus_tag="VU722_001234"
     CDS             complement(30302..30844)
                     /locus_tag="VU722_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU1772211.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKARISRS
                     SFYTHYKDKYDMIEYYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            30952..32552
                     /locus_tag="VU722_001235"
                     /pseudo
     CDS             30952..32552
                     /locus_tag="VU722_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
BASE COUNT        10365 a         5805 c         5723 g        10673 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccaa ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tcctcttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatt ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccgatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacatgga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgttcgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtaa aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tcttttttat agaagaaaaa tatcaaatgg aatttttttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacaatcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa ttagcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agtgttagcg ttagcattac cgtttcgttt agcaatagct tcctctaata actgcgaata
     6421 caattcaaaa ccaacagaat caatgaaacc agactgggat tttcctaaaa gatttcctgc
     6481 tccacgaatc gaaagatctc gcattgcaat cttaaagcca gagcccaatt ctgtaaatcc
     6541 tttaatcgct tctaatctct tttcagagac ttcactgatt gatttttctg gacgatacat
     6601 gagataagca taagcaatac gattactacg accgactctt cctcttaact gatataaggt
     6661 tgacaagccc atatggtccg cattttcaat aaataaagta ttagcatttg gaatgtccac
     6721 ccctgtctca ataatagtag tcgtcaccaa gatatcgtat tgtccctcaa taaagtctaa
     6781 tagagtattt tccaactgga cttcactcat tcgaccatga acatatccaa tcgaagcctc
     6841 cggaatcaac tcctgtaatt ctgaaacctt ctgaacaatt gtgtcaactt tgttgtaaag
     6901 atagtaaact tgacctccac gctccatttc acgcaagaca gcatcacgaa tgacactatc
     6961 attcttttcc aaaacatagg tctgaacagg atagcgatta gtcggcggag tttcaataac
     7021 agataaatct ctgattccca gcatagacat atggagggta cgagggattg gcgtagcggt
     7081 caaggttagg acatccactt gtttcttcag ttctttcaaa gtttccttat gcttgacacc
     7141 aaatcgctgt tcctcatcaa taatcatcaa gcccaaatca gcaaacacaa catcttttga
     7201 caaaacacga tgtgttccaa tcaaaatatc gacttgaccg tttttcaatt tttcaagtgt
     7261 tgcagtctgc tcttttttac ttctaaagcg actcaacaca tcaacattaa ctgcaaaatt
     7321 ttggaatcgt tccttaaaat tcgtatagtg ctgttgcgct aaaaccgtcg tcggaactag
     7381 aatgacaacc tgtttgtgat cattgactgc tttaaaggct gcacgcatag caacttcagt
     7441 ctttccaaaa ccaacatccc caactaaaag tcgatccatt ggctgagaag cctgcatatc
     7501 cctcttgatt tcctcaatac tacgaagttg atcatccgtt tcaacataag ggaaagcatc
     7561 atcaaaggca tcttgatcat catcatcagc tgagaaagca aaacccttca actgactacg
     7621 ttcagagtag agtttgatta aatcatcagc tatatcctct acctggttct taaccttttg
     7681 cttggccttt ttaaaatgac cgtcatttaa tttattgagt tttggagctt taccatcact
     7741 tgaaatatat ttggacagta gatgaatctg ttccacgggg atagaaattt gatcaccatt
     7801 ttggtattgg acactgacat aatcgcgatg aattcccttg atttcaatgg tttcaattcc
     7861 tagatattga ccaatcccat ggatatgatg gacaacatag tccccttttt caagttcatt
     7921 gtaatctttt aatctctctg catttgaaac atgttgtctt cgaaaacgac gctttaattt
     7981 cttttgaaaa atctcatgtt cagttatcaa taaaatcttt tcatctacaa aatgaaaacc
     8041 atgtctgaga ttaccctcta ttaagtttac agattcttta cagatacttg tcttatctct
     8101 agaatccaat ttaatctgat attcctctaa catatcctcc aatgttttac ttcccattga
     8161 attgctagac tgcagaataa tggtgtaatc cattttttta tatcgttcaa tttcttcttt
     8221 tagaaaagaa aactgattga aaaattcctg cataggatat tgattgaatt gataaatttt
     8281 gtcaaatttg agatttccta aacccttttg aagattagag aaaaaggtca ctggactttg
     8341 ttttttatag atttgttcaa tatcagaaaa atactgcata tcagaaaatg ctttactatt
     8401 ctgtaattct tctgtaaagt actgcgctaa gtctctttca aagacttcat actgattcat
     8461 caatttttga taatcatcaa agaatattgg agtatctttt tcaatataat caaagacagt
     8521 ccatgtctta tcatagcaca aagataaaaa cttccgagag tctgcatgac tttgtttttg
     8581 gtgaaaactt gaaagaattt cttccaggta tgatttcaaa ataggtgata aagtttttga
     8641 aatttgtttt tctaaagctg actgtcctcg ttgataatcc ttttctctca aaagcatatc
     8701 actagctgga aagatagtga gttctgtctt attttctttc gataattgtg tttctacttc
     8761 aaatgacctg ataccatcaa tttcatcacc aaaaaactca attcgacaag gttctaactg
     8821 ggatatttca aaaatatcta aaatatctcc tcgaagacta aattcgccct gagtttgtac
     8881 ttgagtaact tttcgatagc cattttcctt taactgatgg ataaacgcgt gttgatcata
     8941 ttcttcacca actgagattt ttacaatact atctttgaat gcattgggag acggtaaaat
     9001 caatcgactt gctgcgatat tacaaactaa aatccctttc ttagatgaat cagtcaaaaa
     9061 acgcaaggct tcaacccgtg aaataatttt ttcctgtgaa gacatcaaaa actccaccat
     9121 aggagcatca tctaccaaaa atggatagac gagttcctca cccaagatag atataagatc
     9181 actaacaagt ccttctgctt ctccataagt tgacgtcaat aacacaatcc tatcttcttt
     9241 ttctaaactg cttgcaattg caagagcctt agtagatgtt gataaaccaa gtattagttg
     9301 tcttttctta tctgttaaat tttgatgcca ttttttaatc tgatcatttt ctgagaataa
     9361 atctaataag gtcaccattt atccgttata cctctgcatt gttttctcaa aatttttctc
     9421 ttgtaaatag tagtttacag aatcgtcaac tttgtcaaca gactgtaaaa taccgatata
     9481 atcatccctg tcaaacttac tcaaaacatg atgaacaact gacataccat ttttaggtct
     9541 tccaattcca atcttaacac ggttaaagac ctgagttcct atatgttgaa taatagactt
     9601 gataccatta tgaccacctg ctgagccttt tgctcttaaa cgaattttcc caacttccat
     9661 gtcaagatca tcgtaaatga taagtaaatc gtcaatatcc aaaccatagt aagttaataa
     9721 agcatgaact gcttttccac tttcattcat aaaggtcgtt ggtttaacca gataaatttt
     9781 ttctccattt aggaaaaagg atgctaggtc agcttgaaat atcttatcgt gtgtaaaagt
     9841 gacattctgt ttcttcgcta gttgatcaat caacataaaa ccaacattgt gttttgtttc
     9901 aaaatattta tcccctggat ttcccaagcc tacaagtaat ttggtcattt atttttcctt
     9961 tcaaaagcca aaagggttgg aatttttttc caacctaatt gacaccattt attaattttt
    10021 agacattaaa gcggaattcc atgatatcgc catcttgaac gatatattct tttccttctt
    10081 cacgcaagcg tccagcttct tttacggcct tttcagattc gtatttcact agatcctcat
    10141 atgacatggt tactgcacga ataaagcctt tttcaaagtc tgagtggata ataccagctg
    10201 cttgaggagc cttcatacca cgtttgaaag tccaagcgcg aacttctttt tcaccagctg
    10261 tgaagtaagt tcccaatcca agcaagtggt aagctgcacg cgtcaactta tctacacctg
    10321 attctatcaa accaatggct tcaagaaact cttttttatc ttcatcatcc aattcagaaa
    10381 tttcttcctc agcacgcgca gaaataacga ctacttcagc attttctgtc gctgcaaatt
    10441 cacgaatttg tttgacatag tcgatagagt caggttctga aaccacatcc tcgtccacat
    10501 tagctacata aagaactggt ttagtcgtca aaaggaaaag acctttgaca accttttgtt
    10561 cctcatctgt aaattcaatg gtacgagctg atttcccgtc ttctaggact ggtttaatct
    10621 tttgaagaac attgaattct gctactgatt ctttatcttt ttgcgtacgt gccatctttt
    10681 ctacacgcgc atatcgttta ttgactgatt ctaagtctgc aagaatcaat tctaggttaa
    10741 tggtgtcaat atctgcaagt ggatccacaa aggcgtcttc acgtccttgc tcgcgcatta
    10801 cattttcatc atcaaaagca cgaactacgt gaacaatcgc atctacttca cgaatattgg
    10861 ccaagaattt attccctagc ccttctcctt ttgaagctcc ttttacaatc cctgcaatat
    10921 ctgtaaattc aaatgttgtg ggaactgtct ttttaggagt tatcatttca gttagttttt
    10981 gtaggcgttc atctggaact tccaccattc caacatttgg atcaatcgtc gcaaatgggt
    11041 agtttgctgc ctctgctcct gcttttgtaa ttgcattaaa tagtgttgat ttaccaacgt
    11101 ttggcaaacc aacgatacct gctgtcaaag ccatatttct cattctccgt tttcatttca
    11161 atccctaata ttataacaca aaaaggggaa acttgctaaa attccttgat atagctattt
    11221 cccataactg aaataataat tttatggact tttttaggaa ctttttaatt tttcaatagc
    11281 tttttcataa aatgaagtag catttttctg attgtctttg gataggtggc tataaatatc
    11341 catggtcata gaaagttttg catgaccgag ccgtgtttgt atctctttgt aaggtagtcc
    11401 agcattgagc aagatactag catgagtgtg gcggaaggcg tggaacgtaa aacgagggca
    11461 tccagcccgt tccaaatgtt ttactaacct gaaactaagc attctagcgt ctatatgctt
    11521 atcaaagcta ttagagaata ctttctcata ggtcaacccc atttctttcc ctatttggga
    11581 ttgtcttgct ttatagagcc gtagcatgag caccgtctta ttatccaagt caattaccct
    11641 aatacttgat ttagtcttag ggccagtgat ttctttgata atatttaacg ttttatttac
    11701 gtctagtgtg ccgtttttta ggtcaatatc agaccactct aaggctagac actcacgaat
    11761 gcgcaaacca gtcgctaaaa gcgtcttata tagcaccgta tcgtagaaat ttttgtaagt
    11821 gtttggcagc tgctccaggt aagtcaagaa tttttttaag ttatcatcat ccagatattt
    11881 cagtttttgc cctttttttt ccttacgacg tggcacgata atatcacggg cagggttgaa
    11941 ggggatagct tgcaaagata cggcatattt aagtatgcgt ttgtttagcg agtgaaggag
    12001 aggatactct tgaaaccctt tgcctagttg attatagtct tttgcccatt gattgacttg
    12061 cttttgaatg attgggggcg tcagtttatc cagcctataa tttccgaaag ctggaagtag
    12121 atatttatct attttgaatt tggtacccat taaggtcgat tttttaaccg tatggcagta
    12181 ggtttctagc caattctcca ccagttcggc gtaagtcttt atctcaactg ctttatatac
    12241 tgtagacccg tctttttcaa agtcgattta agcctgtagc gctttggctt tgagttctct
    12301 cttggttcgc cctgatatag tcgtcttgac tttcttacct gttacggtat cgataccaag
    12361 gtagacgcta gagcgataga ctgtagaccc gtcttttttg gtgtattctg ttattttcat
    12421 gatgataaac ctttctaaaa tacatcagca ggcaagctat tattaaaaag gttttagatt
    12481 atggtttata tcatgttgag cttacgggaa agattttatt tgttattttc ttcagctaaa
    12541 gctatctgta caagtttttc ttttactttt tcagtgagtt cctcatagta gagaattgaa
    12601 gaaataattt cttttaaaaa attgaaatcg attaacccca ttgctaccca taagacaata
    12661 ttttccattg tttcgataaa gaagggaatg aggtaatcaa ggtgattgat tgttaaaaat
    12721 ttaataccga agacaatgct acttctctta tttccatcat tgaacatatg aaattgaact
    12781 gtattaaata ctagcactgt aagttttgtt tcaaagtctg gatagtaatc gtcattctgt
    12841 aagtgttcaa atacactaaa tacccttccc ttatctttaa caccgtgtaa accacctatt
    12901 ttctcaatta cttcaatgtc gtgtagtaaa attgcttctt cagcagaaaa ataattgatt
    12961 ttatccatta tttatctctc aatctttcaa aaacttggcg gtgttcatca atttgttccg
    13021 aaagtgattt actttgttcg ccaataaatc tttcaaaatc ttcttcagaa attggacgga
    13081 tatattctgc taatttctca tgtttggcat tcctgaaaga tagatcccta ctagccattt
    13141 tctctctggc atgcattaaa tggggttctt gcattgggtg atttgctaat ctctgaatta
    13201 tctcgattac atcagtatta gttagttttt gatttgaaga cttactcttt tgttcaatct
    13261 cataagcaac ccctttttca aaactagcaa taactataag tacctcacta tacattgttg
    13321 cgcgagcatt atcattttta ttcaatttca gtattttttt atattctgat gctctttctt
    13381 taaagattgc tttgtaaatt tcattcgtta attgaccata tttaaaatta cttccagaga
    13441 catacttatc aatggcattt gtaaatattt ttctagcatt atcttcttct aatgcagtcg
    13501 atagataatt tttgtcacgc tggtttataa attttacatg gccaccagtc ttctcagtta
    13561 acacattaat gacaatatca agtagggtat ttcttacttg cttagctata tcactattgg
    13621 ttaacaacat agcaaaatta agcaatgttc tgaacgatga gatacttaat tgtgtaactt
    13681 tgctaccgac atttgtgtcg gtagcaaaag cattttcttt aaatttagct agtttttctc
    13741 cacgtaaagt gtgataacca ttttcagtaa gctccgtttt atgagcttca acaagtcttt
    13801 caatagttcg aatgtcgact tcgaaaaagg tagctagctg agaatttgta aaataaaaag
    13861 tatcctcaaa gtagaaacca ggtactttta aaatctcttc agctttttgt aatgctaaag
    13921 aattatttaa aatattttgt ctttctattt gtgaggttgt cagatcagtc ataatttctc
    13981 ctttttgtcg agttaatttg ccaataactc ccgatatttc aagagtttta ttttattttc
    14041 gtgtcgttag agtatattag aaaatcttga actccgcgaa tacacgcgct tcaggattgt
    14101 tgaacattgt ggcgcgtggg ttagtcgctg aagtgttccc tgatttcttc agctaaatca
    14161 ttcaagcggt tctgaatacc tttatagtaa tcaaattcaa tggtgtcaat gatgtcactt
    14221 ttttcagtaa atatcttgtt ttttgtaaca caaaagctat tatttgtatt attgtgaaca
    14281 aggtcattta tctcattttg aacagaagat attttccttt gtaagcaata gcctaagatt
    14341 tttcgatctt gaatacctat tttttcaatt atttcattca cttcaaagac aactgcccca
    14401 tagctatcaa ttttattgtt aaggctattg ataagattag aaatttcaga atgcacatag
    14461 gaggtattga gagcttgctc acgttcaata acgtttatta aacgtgtaat atattcgtta
    14521 gtaatcatgg tgagtacatt attataagcg tactccctag cttcgcgctg tttggaaagt
    14581 agtagagcct cattattttt tgagatatct gataaatcaa gtccgttgaa aatttcaaca
    14641 ataccagggt ttattattga agactgaaga acgcgaccca aaacaccctg gtcaaatgct
    14701 atttttcctc gaatgtactc catattcata taatcttttt taaagctaag tatttctttg
    14761 attttattga agaacatctc aaaaaccttt tctctttgat tattatctag caactctttt
    14821 agtgtgctgg ttgaaactgt atcaataaac cgcagatcta ggaaagattt ttttacgttc
    14881 aaaaaatcag ctattttttg taaattccca gcggttggta aagattttcc ttttacatat
    14941 cccgtaattg tacttttagg aatatctaaa gcgttatgaa ggtcaatttg tctaacccct
    15001 ttttgttcca taagaaggtt gagccgttta gagaagtatt ctctattttc aagatcttga
    15061 ggactatttt tagccatgac tttaaccctt tcagttgtaa gttatacatt gattataaca
    15121 caaaataaaa acaaagtacg aaaataatag tactattaac ttatcacttt tgaaaggaat
    15181 tgttagatta tatggaacaa tggacgttga aagcctgtag agtaaacgct ggttatactt
    15241 tgcgacagat tgctaaaaag gtaaataaga attttcaaac tgtctccaag tacgaaaaag
    15301 atagtacata tataccgttt gaacttttaa aagaattgtc tgcaatttac caagttaaat
    15361 tggacaatat ttttttagga gacagtacga aaaaaataga actaaataaa agagaggtgc
    15421 aataatgaga gtattatttt aagtcaatgg tggcagaaat caaaccagac ataacaatag
    15481 atgaattatt ttatagctag aaaggagcaa accaatggaa ctagtctaca tggacggaaa
    15541 gaaagagccg tatactacga gtgagatcat cgctgaatgt gctggagtca ctcatcacac
    15601 aatacaagaa cttttaagga agcataaagc tgattttgaa agctacggaa ttatcgcatt
    15661 tgaaatgcga taattagacg gccgagggag accaatgaaa atatatctcc taaatgaaca
    15721 acaagcgacc ttgctgatca cttatttaaa gaatactgaa cctgtacggc ggttcaaaat
    15781 gaacctagtc aaagcattct ttgaaatgcg tgaggagctt tctaaacgct atcttcaaag
    15841 agaactggaa aagccaaagc gcaagacctt aaccgaagct atcaaatcat gggagaaagc
    15901 gcccaagcat gcctatagta cacttacaaa cctactgcta aagggagcga ctgggaaaaa
    15961 caaagcccaa ctcatgcaag agcgagaaag tgaaaacggt attgacagtt taacaagcgc
    16021 ggaactgaca aactaccaac gtttggaaga tatggcaata gcgatgatta acttgaatag
    16081 ggtgtattca gaaattgaag aactaatttt taaagcatag gagtatagaa aatggaaaat
    16141 gaatttaaga cagttacaaa tgccaaaggg ttagaaattc ctaagtatcc caaggatttt
    16201 aaaaagctag ttgagatgga cagacaacta gccgaatatc tttgtatgaa ctatgagaac
    16261 ttggacaatg aagacctagg cgcatttctt gaaacggtgg agcagggatt cagctggatt
    16321 ctggatctta tcgaaagtaa agatttgctt tatagccccc agacagggaa gaaagcaaga
    16381 aaaagacaat aaaaaaagtc acttgctgat agtttggcga ccgaggcaag cgacaagatt
    16441 tagggtatag atattttttc tatacctaga ttatagcata atatagcggt ttccgctagt
    16501 acattgaaaa taaaataagg tacgctggga agattttaaa tttttttcgg tttaggggtt
    16561 gacttaaagg gtacaccgtt acataataaa agggtacccc gaaagaaaga gaggtcaaaa
    16621 atggggaaaa cattaggacg acctaaaagc gataacccaa aaaacaagca actaaaaatt
    16681 aaaatgactg aacaggattt taataattta gaagaacttg ccaaaaagaa aaacatgact
    16741 aaaacagata tagtcatgcg agggattgag cttgtaaagt ctgaaccata acgaaaccgc
    16801 ctaccgtgtc acttgtttgg cgacagaaca cgatagacgg cgatgcacca caaatgaggt
    16861 acgtaaatat cttatcatgc gtactcttat ttgtcaaaca tagaaataga gtacgctttt
    16921 tgcgtaccca aaaatgaggt atacaatgag aaagaaacat caagtagtaa aatttaaaga
    16981 tattgctgaa aaattgcctg aattagaggg caagcgccta gaagaaatta ctaaagtatt
    17041 aggttaccgt aacctagaga gttgcagaac caacctctgc aagttgaaac aaaacaatcg
    17101 cctagatttt acactagaaa aaggagttta tagcaagttc gcactattag acggtacggt
    17161 aaaagaggaa ttggaagata aagaattgtc agaacgtggg cgctatttga agagtgtaga
    17221 ccgctacaag gcaatgctga atgctttttc tatcgccttt gatagtacgg tcaaggcgga
    17281 aaccagacaa aaagcagaac acgacggctt gaaagccttg gacagaatcc cagataaaca
    17341 ttacgcccta ctttatgaca tgatggaggg ggaggatgga agcaaaaacc cacttcgcta
    17401 gattcatgcg tagaggcatg gagttagcaa ggcaattaca tagtaaagaa attcaacgtg
    17461 atgaatttga tagagcctgg aaaagattag gcgatcaaat cgaaaacgaa acgaagaaaa
    17521 actaagaaaa ccgaagagca ggcaagcaat tagaaaaggt tttgaaaagc atagagcgcc
    17581 aactctttaa actggtactt tctcacgctt tcaatttggc gagtctgagc gtgaggcatg
    17641 tgacaggaaa aactgtataa gaaacaacca ttcaaaatcc ccacactcaa attttggcca
    17701 aggagagcgt gaggatagca attacaagaa aaaagcatta agaagccatc agggcaatta
    17761 caagaaaaaa gcattaagaa gccatcaggg caattacaca acatagaaac agaggtacaa
    17821 gtatggaaga aacaacatac gatattatcg ctaaaagctt ggatagaatt agtatggaat
    17881 tacaccaagc tgacgaaaat aacgattttc tagaatatgg gttttatcag gacaattaaa
    17941 aggccaatgg aggaaaacat gatatcagat aaattagaag ctatttcaac aaatttagaa
    18001 gaaatacaaa aaagccttgt aggggctgaa actgtattag ctaaaagaga aatcagtaga
    18061 gtgttgaacg acttggatga tgtttacagt gaactaacta gcacagaata ccatgaacaa
    18121 cagcaaacga taaaggaaca aacagaaaag atgaaacaga gggggattgc tgaggtaata
    18181 ggtgaactag aagaacgaga agagtcttat tacagaaatt tttggggtga tactcagttt
    18241 ataaggctac tttccaactt tgatggattt cttttcttaa acacttacct agctgaaata
    18301 actaaagaaa atacctaccc aatggaacaa agtcaattat tgaattatgt atgggaagtc
    18361 atagcggttg atatcgcaaa gaaaaaacga ggaaaaaaga acgttttgga ttcatggaca
    18421 gattcatcct tatatactcg tggaatgatg attgattagg aggcaatgca gtgacactag
    18481 acctaggcaa aatgacacaa gcagaatttg atgaagtaat ggctgacatc aaggcaagaa
    18541 atccaaacct attacagctc atcactgatt ttttagatag aaaggtaaca cccgaagagg
    18601 tggacgactt gttgaatatg gagcgagctg aacaagtgga atatattaag aattatcaag
    18661 cgagggcata acatgaatga actagatata agtaacacac atgctgctgt cttaatcgtg
    18721 attttgattg gcttactgct ttatttaaac caccgagacc gcaaaaaaag cgcccaaatt
    18781 gagcgagaaa accaacagac gataaaaaca cctagcgagg atttaaaccc tgattatggg
    18841 cgatatatcc agcttgcagg ggtaagagtt tccggaggga tggaatgagt tacacaatga
    18901 atttataccc cgatattgaa aaaataccag atgaacctta ttttactaaa gatatttttc
    18961 tagctacgtg tatggacaat gcaacaaagt tagctgtaac tatgagcttg ttgacagaac
    19021 aaacgttgga tttagagact gagacagcta ttttgaaaac cttggataca atcatagaaa
    19081 ctcaaaaaga tattttgcaa ggggtagcga gcggacaaat aacctttgta aataaaagca
    19141 aaggagagga ggggttggat gagtctatca gagaatgaca agcgagtttt aagactaatc
    19201 aaggtagggg ctgagaactc cataacaggg tcagaaatta gcctgacaac caagctaact
    19261 gaaagaactg tacgtgacat tatcaagcgt ctagtagtta agcacaacat ccctattgta
    19321 ggggttagat gtggcgtttt tagtgggtac tttattccag cgaataaagg cgagttacta
    19381 gatggcgcta aggcttttta caaccaagta caggaggaga gcaagcgcct agcggtgttg
    19441 atgaatagcg acctagaaag ctacaaagaa accttgaagg aggtgggcgg atatgtttag
    19501 cttaagccga gaaagtgagc atgatttgac gcatggcatt ctggaggtag tggaaagata
    19561 cctggaagcg cgtgagaaag taccgccaag attgaccaag ttaataaata gagttgaact
    19621 caaagaagag ttaaaaatta gtgacaacac gctgaataag tgggaaagtc agggtttaag
    19681 acgctatcaa ccaccggacg atggtgctag aataatattt tatttagtgg atgacattcg
    19741 taggtttatg ggggtggaga atgggtagat ataacacaca cccagcgcaa ggcggaggtc
    19801 attatcatga cattaaattg tataagcacc gtggcagatc tttggaacag ttccaagaac
    19861 aaaagctact gaagaagtta aaaaaaacgc aaaaaggggc gatagtatga caatttatga
    19921 ggctagaggt ttccagagta atcttgtcta tccatttgat aagatggagc cgttccagta
    19981 cattgaacgc tttaagcctt tggtagtccc tgaaggggca aacattgaag aatttaaacg
    20041 tatacaagcg ccttactgta ttagtggcaa agtgacacca gaaaagaatg gcagttacaa
    20101 gcgaaacaac accagtctaa tctatcggga tttgattttc cttgattatg acgatataca
    20161 ggggacgact gaggatttca tagaagccgt ttctagcgct ttgtttggct actcttatat
    20221 cttatacccg actatcaaac aaggcttata tttagagctt gcagctttag aaagtggtat
    20281 tatcaaaaag caagaactaa gcaataccag agtacaaaca agcagggtaa atacgaccga
    20341 gaataacctt ataaatgttc taaaactaaa agagtacact ttacagagaa ttgagcgact
    20401 tactgaagag agaatggaaa tatctaggct aatcgataag ctagccaatc cgcttgaacg
    20461 ttctgttctc aggctgttct acttgaatgt tcttgacgct tggcaagttg ctgaggaaat
    20521 agataaatca aagactgcag tatacattat aaggcaaaaa gctatagaac acttagcaaa
    20581 tgtggggtaa taggtgagca caaaaaaacg cctagaacaa tctaagcgct aaagagtagt
    20641 ggacggtgtg cctgtcccgt catctcatac tatgaagttg cgtagcgaca ctatcatctc
    20701 tacctcactt ctctttagac taattatacc acaaaggagc gaactaatgg agctggataa
    20761 gtttaaaacg atgatgaacg tcagagaacg gatgacctac tttctacgtt tccagaggat
    20821 ggcagggagt gaaaaccaag ttacaataga cgaagaggct tggaaacttg tcttacctga
    20881 tcagtggaat ttgactagta agcatgaaaa agcaatccgt gaggggttgg aaatattcgc
    20941 ccaagacatc aacagtatag agaacaaacg agctagaaaa tactttatta tccattattg
    21001 ttacatgaga aagaaaacaa tgagcgaatg cgtagaaatg gcagctacta gctccactag
    21061 ctaccaccga tataaacaaa tagccgtctt aaattttgcg agaatccacc agaacggaga
    21121 gctagaagtg tataagtagg catttgtggt gttttgttga gaaatgttga gatttaagtg
    21181 aagggggatg acatgattga agattttttg attgatttgg ataatatcca attagaggat
    21241 atggagatag attttaacat ggatatagac atcgatttaa acatagattt tgaccttgat
    21301 ggtttagatt tgaccttact acaagaatta gaagcgtaaa tgttggtaaa tgtaggctga
    21361 ggcttcatat tcgcctccct atttcgcttg gtttcgtccc ggacgattaa aacaccatgg
    21421 ataaactaga agcccttaga aacgaatcag ggggactttt gtgaggtcat aatcttataa
    21481 accacgcgct tcatggtata atatacctat cagcaaccag caataaaaaa agcacgtttg
    21541 accgtgctag tttcttgcct gctgaactcg tcatttattg cccttttgtg gggctttttt
    21601 tgtggacttt ttgagaattt ttaagaactt ttaatgattt ctaatcaaat gagatttttc
    21661 aaaaagtcag taatatcaaa ggtttaggcg ctataaacaa gtttaaaagc gtgtagatta
    21721 caatctaaca caaaaaggga taaagtgcta accctctaat taagggttct cagtcaataa
    21781 ttttattcat ttttcgatca aaatcatatc gccccatcat gacaacatgc tcacaattac
    21841 tgcattttat tttgatatct gctcctacac gtgtaatttc ccaacgatta gcctttttac
    21901 cagtcgactt gattgtacaa gcgtgtggtt ttttcatctc aacaaaattt ccaacttgat
    21961 acatactact ctccttttct ttttcgatta tatcataaaa gaggcgagcc aggctcaacc
    22021 tctttcactt aatttgtacg aactggtgta atgagctgca tgaagtcttc gtcagtatct
    22081 gctggcacaa gagtaaatgg acgaacagct gagataaagc taatggtcac cttttcgcta
    22141 tttaaagctt taagagaatc aatcaagtaa gttgggttga aactaatggt caaatcttca
    22201 ccagtaacct gatcagtatc gatttcttcg tttactttac caacttctgg agagtgaaca
    22261 tgggcgctaa caaccccatc cttaatttca agtttcacag taccattttg agtcgcactt
    22321 gataaaagac gggcacgctc cattgactgg cgtaagttta ccacattaaa agtaatagta
    22381 gtgttaaagt ctgttggaat caagcgatct gtatcaggat agtttccttc taggagacga
    22441 gtatagaagc taatattttc gcttctaaag aggatttggt tattggcaaa gaaaatttct
    22501 acagtttcga tatcatctgt aaataccgct gaaaattcgc gtagagaacg gctaggaatt
    22561 acgacatcaa aatcatcact atttttttca agagtcaatt ttttctggct taggcgatga
    22621 gagtctgttg caactgtttt taactctttg tgttgactca atacgaagtg gacacctgtt
    22681 aaaatcggac gactctcttg tgtacttgca gcaaaggctg tttcattaat aattttcttg
    22741 agtaattttg tttcaagtat taaaggagtg cttgctgaaa tttcttggat tcgtggatat
    22801 tgttcgctat cttttccttt tagggtaatt tctgatttgc cactggttaa aacaatttga
    22861 ttttgttcaa tttctttaaa atcaagagtc acatcaggta aactagatac tacattgata
    22921 aagaaagaag cttcaagaag gatcgaacct aaagaagtaa ttaacaaacc agcatcttca
    22981 tttttttgag aaataaaatt ttcaattgaa atttgaccat ttgaaccaat taaagtaata
    23041 ccttcattgg tcacgtcaat ttttactgtt gataaaatag gaatggcatt tttagaacta
    23101 atagctctct tagtagtatt taatgcttgt agaaataaat ttttattaat tgaaaaatgc
    23161 atcatggatt ctcctttatt tatttttagt attagaaaga taatagtaat aatagagtct
    23221 gtgaaatctg tggaaaacag cctttaaaca agtcatatca agttttttag cttgtttaaa
    23281 aaatgtggat aaaaaagata aaaaagtaaa agttatccac aaattatttg attttctttt
    23341 tgattgattc aatttctaaa cgtaaattat cgtcttgatc aatcaaagat tttattttgg
    23401 catgggcatg aatgactgtg gtatgatctt ttcccccaaa ttccttccca atttttggaa
    23461 gactattatc tgttagttct ctagataaat acatggctac ttgacgggcc aaaacaatat
    23521 tttgaaggcg tctacttccc ttcatttctt tgatactaac accataaaag ttaccaactt
    23581 cagtttggat tttatcaatt gggatgacga gcatttggct aacatcttgt ttgcgggctc
    23641 taatggcttc tgcagcaata tcaatagtga tatccttgat tttttttact ctggcaatta
    23701 aagtgatgtc gttgatggct ccctcaagat ctcgaacatt tgaatcaaat tgcccagcta
    23761 ggtattctag agtatcactt tggaaattgt agcctaaatg ttccgtttta ctttgtaaaa
    23821 tggcaatacg tgtttcaaag tcagggggtg tgatagtttg tgtcaatccc caactaaaac
    23881 gcgtgacaag cctctcctcg agcccttcta gatgttttgg actacgatca ctcgttagga
    23941 caatctgttt ttgcttgtca tgaagggcgt taaaggtatt gaaaaattct tcctgagttg
    24001 cgactttttt tccgctgagt gactggatat catcgattaa caaaagatca agactacgat
    24061 aggtcttttt aaacttttcc atttccccaa gtcttaggtg atcaagaaag tcattaataa
    24121 agctttcggc aggaatatat ttaacacgcg cattaggaat attttttaga atttcatttc
    24181 caatagcgtt taataagtga gtcttaccaa ggcctggtcc tccatagata aaaagagggt
    24241 tataggtcag agctaaatct tcagagacag ctaaagcggc tgatacagcc caaacatttc
    24301 catccccttg aataaagtta tcaaaggtat atttttcttt taatcccgta tctgaataag
    24361 gaatagatac taactttgga ctatagttat aaagagttaa atttgtagct tcttcaactt
    24421 gtgagctagt cgtatcttga ggtttggtga aaatatagtg gggagttatt tcagcgtcat
    24481 aaatttcaaa accagctact acaataatat cttttagttg tttttcccag accatttcca
    24541 tttcagagcg aggtagaaat atagtggcaa cattttcctc taccttgatg agttcagctt
    24601 gaatagcata gaaatcatac atggatcgag tcagtctttc ttgtgcaaat tctaatatac
    24661 gattccaaaa ttgtttttct ttcaatcctt tctcctcctt tactatttaa aagtttaata
    24721 ctagagatat tttaccatag atagcaagaa ttttccacaa gttgtgaaaa ataatccaca
    24781 atgttaccaa actttatcca caggttgggg ataaaagaag aaattattga tttattaagc
    24841 tttttatcga aaaacatagt ggataacctt gtgagataaa aaaataaaag aacagcctta
    24901 tttcaggctg ttgataattc tactatattc ttcttgattt gaaaaagaaa taatgatttt
    24961 tccactgtct tttttagata gtttaatttc tacatctaat ccgagtagtt ttcttaactg
    25021 tttttcttca ttgtgtatga aatgattagt tttttgctgt ttcttttgtt ttttctctgt
    25081 cagaagagct tctaacttcc ttacagaaat atcttcttct ataatccgtt gaaagaaata
    25141 gtcttgttgt tccttattta atccaactag ggaacgcgca tgggcttgtg atagtttgcc
    25201 attttctact tctgagagaa tttgttctgg caaggaaagt aaacgaatgg agttgctgat
    25261 atatggacga gacttgccca ttttatctgc aatttcagca tgggtgaatc ctttctctac
    25321 gagagattca taggcgcgtg cttcttctat tgggtttaaa ttttctctct gtaaattttc
    25381 aataatggac tggaccatca tctcttggtc tgaaatctgt ttaacaacag ctgggataga
    25441 ccgtagacca gctaaaagtg aagcccgata gcgtctctct cctgcaagga tttcataacc
    25501 aataacagga gattgacgaa caataatcgg ttgaatgacc ccattttctt tgatagattg
    25561 tgctagttca tctagttttt ctctatcaaa ttcttttcgg ggttgatagg gatttttttg
    25621 tatatctgtg atagaaatca tttcaaattt ttccatgatt ctacactaac acatcttttc
    25681 tcttatgtaa agctttcttt acatagatgt caattaagat tctaaatcac ctgaactctt
    25741 gtcaagtttg atagaggtag tttcttcttt cccgttacga tagtaggtta tcttaatggt
    25801 gtctccgata gaatggttgt aaagagcact ttgtaagtct gttgatgaag caatctcttt
    25861 gtcatctact tttgtaatca catcgtattt ttcaaggtga ccattggcag gcatattact
    25921 ttgtaccgaa cgaacaacta caccagatgt aacattactt ggaatattga gtcttctgat
    25981 gtcgcttgta ctcacattag ataaattaac catctggatt cccaaagctg gacgcgtcac
    26041 ttttccgttt ttttctaact gttcaataat attgatagca tcatttgcag gaattgcgaa
    26101 accaagacct tctacagatg ttcctccatt tgtagcaatt ttacttgagg taattccgat
    26161 aacctgccct tgaatattga tcagtgggcc gccagagtta cctgggttaa tagcagtatc
    26221 agtttggatg gcttttgtag aaatagcttg tccatcttcc gattttaagg atacatttct
    26281 attgagactg gatacgatac cttgagtgac agtatttgca tattcagaac ctaacgggct
    26341 accgatggca atagcaattt ctcctacagt taacttacta gaatcaccaa actcagctac
    26401 tgttgtcact ttttctgaag agattttgac gacagcaata tcagagaaag tgtcagctcc
    26461 gacaatttct ccaggtactt tagtcccatc tgacaatcga atatctactt tgctggcgcc
    26521 atttataacg tgattgttgg tgacgatgta agcttcttta tcattctttt tataaataac
    26581 tccagatcct tcactagaga ttcgctgaga atctgtgtca gtatcatcat tgccaaatac
    26641 gctattttgt ctgtttgccg aataagtaat aacagaaaca acagcatctt ttactttgtt
    26701 aacagcctgt gttgttgaat tttcgttctt ataggcagtt tgtgtaatag tactattgtt
    26761 gttagagttg tttacactac ttttttgagt tagttgagtt attgaaaaac tacccaaggc
    26821 tccactaaaa aagctaatga cgataacgac taataattga aaccattttt tgtaaaatgt
    26881 ttttagatgt ttcatatttg cctccatatg tttgaattac tgaaagtata aactgactag
    26941 cttaattata acttaaacac aaaagtttta cacaaactgt ggataactct tttgaaactg
    27001 tgattttctt aattgaaatc tattttttat tttgtgaata agatgtgaaa aaatagagaa
    27061 tatgttagaa tagagtcatg aaaattaaag ttgtaacagt tgggaaactg aaagaaaagt
    27121 atttaaaaga tggtatcgca gagtattcaa aacgaatttc tagatttgct aagtttgaaa
    27181 tgattgagtt atcagatgaa aaaacaccag ataaggccag tgaatcagaa aatcaaaaga
    27241 ttttagaaat agaaggtcag agaattttat caaaaattgc tgaccgtgat ttcgttattg
    27301 tgttagccat tgaagggaaa actttcttct cagaagaatt tagtaagcag ttagaagaaa
    27361 cttctataaa aggattttct acttttactt ttattattgg gggaagttta ggattgtcat
    27421 catctgtaaa aaatagagcc aatctttctg tcagttttgg tcgcctaacc ttgcctcatc
    27481 agttaatgag actagttctt gttgaacaaa tctatcgcgc ttttacgatt cagcagggat
    27541 tcccctacca taaatagaaa attgactttt aattgaattt ttggtagaat aattgtgtta
    27601 ggtctcatag ctcagctgga tagagcattc gccttctaag cgaacggtcg caggttcgaa
    27661 tcctgctggg atcaatataa tagcaaagct gggaattttc ccggcttttt tcttaaaaaa
    27721 gtacactttg ggagaaaaaa atgacagttg agagaatttt atctaaagcg aaattccatt
    27781 ttgtataatg gtttttgtaa gttagcttac aagaaaaaac attttaggag attttattat
    27841 gaaaaacaca gttaaattgg aacagtttgt agctttgaag gaaaaagact tacaaaagat
    27901 taaaggtggg gagatgagga tttcaagaat catccttgat tttcttttcc tacgaaaaaa
    27961 gtaatgaaat aaggagaaag agtaatggat ttacttggat ttgggacagt tattgttcat
    28021 tttttaatta ttagtcacag ttaccgttta atttgtaaag gtcgaataaa tagaaaagaa
    28081 ttatacgttt ttggtgctta tacattacta actgaaatag tacttgaatt ttccttttat
    28141 cttctatatt tagataaaat agggattgaa agatttttat ttcctttggg cttatattcc
    28201 tattttcgat ggatgaaaca gtatgagagg gatagaggac tattcctaag tttactacta
    28261 tctcttttat atgagagcac tcataacttt ctgtccgtaa ctttctcctc tataacagga
    28321 gataattttg ttttacaata tcatttccca ttctttttcg ttgtgacggt gttaacctat
    28381 tttgttacat taaaaatcat ttattatttc catttggaac tagcctattt tgacaaggac
    28441 tacctttatc ctttcttgaa aaaagtattt tttgctttac tattgctaca tattgtatct
    28501 ttcgtttcag atatggtaag tacgattaaa catttgaata gttttggaag tattttgtca
    28561 tctattgtct ttatctctct ccttttgacc ttctttgcaa tgaattctca taaagttcaa
    28621 atggagaaag agattgcttt gaagcagaag aaatttgaac agaaacattt acagaattac
    28681 acagatgaaa ttgttggtct gtataatgaa atccgtggtt ttagacatga ttatgctgga
    28741 atgcttgtca gcatgcagat ggcaattgac agtggtaatt tacaggaaat tgacagaatt
    28801 tacaatgaag ttttagtcaa agcaaatcat aaattgcgtt cagataagta cacttacttt
    28861 gatttgaaca acatagaaga ctcagcttta cgaagtttgg ttgctcagtc aattgtctat
    28921 gctcgaaata atggtgtaga gtttacactg gaagtaaaag atacgattac caagcttcca
    28981 attgaactat tggatttggt tcgtatcatg agcgttttat tgaataatgc tgtcgaagga
    29041 tcggctgata gctataaaaa gcagatggaa gtagcagtta ttaagatgga aactgaaaca
    29101 gttattgtga ttcagaattc atgtaaaatg acgatgactc cttcaggaga tctatttgcc
    29161 ttaggattct ccactaaggg aagaaatcgc ggagtcggat taaataatgt gaaagaacta
    29221 ctagataagt acaacaatat tattttagaa acagagatgg aaggcagtac atttagacaa
    29281 atcattagat ttaagaggga atttgaatga aagttttaat tttagaagat gttattgaac
    29341 atcaagtgag actagagaga atattggatg aaatttcgaa agaatcgaat attccaatat
    29401 catacaagac aacgggaaaa gtccgtgaat ttgaagaata cattgaaaat gatgaagtaa
    29461 atcagcttta tttcctagat atcgatattc atggaattga gaaaaaggga tttgaagtgg
    29521 ctcagctcat tcgtcattac aatccttacg ctattatcgt ctttatcact agtcgatcag
    29581 agtttgcgac tctaacctat aaataccagg tatcagccct agattttgtt gataaggata
    29641 tcaatgatga gatgtttaag aagagaattg agcaaaatat cttctacacg aagagtatgt
    29701 tacttgaaaa tgaagatgtt gtagattatt tcgactacaa ttacaaggga aatgatttaa
    29761 aaattcctta ccatgatatt ttgtatattg aaacaacagg ggtatctcat aaattgcgca
    29821 ttattggtaa gaattttgca aaagagtttt atggtaccat gacagatatt caggaaaagg
    29881 acaaacatac tcagcgattt tattctcctc acaagtcatt tttggtaaat ataggcaata
    29941 tcagagaaat tgatcgaaaa aacttagaaa ttgttttcta tgaagaccat cgttgtccta
    30001 tttcaagatt aaaaattaga aaattaaaag atattttaga gaaaaaatct caaaagtgat
    30061 tgacaattag caagaaattg atataatggt tatatctgct acagatagaa ggtccgttgg
    30121 tcaaggggtt aagacaccgc cttttcacgg cggtaacacg ggttcgaatc ccgtacggac
    30181 tattttatcc gccatagctc agttggtagt agcgcatgac tgttaatcat gatgtcgtag
    30241 gttcgagtcc tactggcgga gtatagataa aagggaacac agctgtgttc ctctttttgt
    30301 atcaatttgt atcaccaagc attttcataa ggaagtctgt tatttcttga gaactttctt
    30361 tttttccatg tgcaatccaa gtttggcaga caccaaaaag tgcatgagtt agatagatgc
    30421 tactatattc taattcagtg gtatttagat tcagttgcat aaatcgcttt tgtaaatcta
    30481 tactgagcat gatatgaagt ttatttcgta agaaattttg gatttcttta gtcccatttt
    30541 cagaaagaag ggcagccaga agtggttctg actctagata ttcaaagact tctaaaatag
    30601 cgtctctttt gtgatgagca tgtttttgaa aaatatattc aaatgtatgg aatagcttgc
    30661 tttgatagta ctcaatcata tcatacttat ccttatagtg agtatagaag ctggaacgac
    30721 taattctggc tttttctact aatttgacag tagaaatttt atcaaatggc tgttccatca
    30781 gtaattgtac catagcattt tcaatagttc gctttgtttt taagcgtttg ttactttctt
    30841 gcatatttcc tccttgtaaa caaattagac tatatgtcta aaaatagatt ttttaatgta
    30901 taatccatta tatcaaaatt ttagacaata tgtttaaaaa aaggagaaac tatgtttaaa
    30961 gaatggaaag caatttttaa aaaaccaacc tttattattg tcataatcgg gatttctctt
    31021 attccagctc tgtacaatat catatttttg tcatcaatgt gggacccata tgggcaattg
    31081 tctgacttac ctgtggcagt tgtaaataat gataaagagg cttcctataa tggtaatact
    31141 atggcaatag gaaaagacat ggtgtccaat ttaaaagaaa ataaaacctt ggattttcat
    31201 tttgtagatg aagaggaagg aaagaaggga ttggaagatg gcgattacta tatggtagtg
    31261 actttaccaa gtgatttatc tgaaaaaaca actacattat ccaatattca atcgacagca
    31321 gcttatcaat cattgacaag tgagcaacaa actgagataa gtgattctgt atctcaaaat
    31381 tttcaatcgg ctcagtcaat tgtagcttta gtacaaggtt tgcagggaag tttagaaaac
    31441 ttacaaaatc aatcttctaa tctttcgact ttaaaaaatc aagctaatca agtattacct
    31501 attacttcta cttctttgat aggattgtca agtggattaa cagagataca aggagctgtt
    31561 actagcaaat tagttcctgc cagtcagtcg attgcatcag gtgtaaacgc atatactaca
    31621 ggtgttgata aagtttctca gggcgcaagt caactaagtg aaaaaaatgc caccttgata
    31681 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    31741 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    31801 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    31861 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    31921 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    31981 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    32041 gttgctcttt ttgttgcagc aatatcaaca aatatgatat tttcgaaatt gccttcagga
    32101 cgtcatccag agatccgttg ggcttggttg aaatctcgat ctgaaataaa tggtattata
    32161 gctgttttgg caggaatttt ggtatatgga ggagttcatc ttattggttt aactgctaat
    32221 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    32281 accactttaa caacgtggaa tagccgtata ggagctttct tctcacttat tttgctttta
    32341 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    32401 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctcc
    32461 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatactag
    32521 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgat
//
LOCUS       DAVFJR010000021        32365 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVFJR010000021 DAVFJR010000000
VERSION     DAVFJR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.022"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(69..407)
                     /locus_tag="VU722_001236"
     CDS             complement(69..407)
                     /locus_tag="VU722_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU1772212.1"
                     /translation="MSNIYDSANELSRGLRELPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQDKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(418..1521)
                     /locus_tag="VU722_001237"
     CDS             complement(418..1521)
                     /locus_tag="VU722_001237"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU1772213.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADIIILSLPIKQTISFIKELANLDLKEGVIISDAGSTKSA
                     IVDAAENYLAGKPVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSPDTLEE
                     MKELLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNRETILERIEDFKERLDEVGQAISKGDEEQIWNFFN
                     QAREQRQAMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVVK"
     gene            complement(1531..2697)
                     /gene="aroC"
                     /locus_tag="VU722_001238"
     CDS             complement(1531..2697)
                     /gene="aroC"
                     /locus_tag="VU722_001238"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU1772214.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQERGQEIKDYIDKIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(2707..3774)
                     /locus_tag="VU722_001239"
     CDS             complement(2707..3774)
                     /locus_tag="VU722_001239"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU1772215.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(3793..4647)
                     /locus_tag="VU722_001240"
     CDS             complement(3793..4647)
                     /locus_tag="VU722_001240"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU1772216.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGTYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(4637..5314)
                     /locus_tag="VU722_001241"
     CDS             complement(4637..5314)
                     /locus_tag="VU722_001241"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU1772217.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLGFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAAMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTMSMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(5311..6474)
                     /locus_tag="VU722_001242"
     CDS             complement(5311..6474)
                     /locus_tag="VU722_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU1772218.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASELENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSTYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVVAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(7161..8795)
                     /locus_tag="VU722_001243"
     CDS             complement(7161..8795)
                     /locus_tag="VU722_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772219.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFVLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTIKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(8776..9525)
                     /locus_tag="VU722_001244"
     CDS             complement(8776..9525)
                     /locus_tag="VU722_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772220.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            9704..11158
                     /locus_tag="VU722_001245"
     CDS             9704..11158
                     /locus_tag="VU722_001245"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU1772221.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFDASRAGSNYNLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEVLDRLLTIR
                     KDLAYGEQTDYFDDANCIGWVRSGAENQSPIAVLISNDQENSKSMFIGQEWAKQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSAASVSVWATNTI"
     gene            complement(11248..13866)
                     /gene="alaS"
                     /locus_tag="VU722_001246"
     CDS             complement(11248..13866)
                     /gene="alaS"
                     /locus_tag="VU722_001246"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU1772222.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGSSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETPFYAEMGGQVA
                     DHGQILNASGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDTNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIVDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(13888..14373)
                     /locus_tag="VU722_001247"
     CDS             complement(13888..14373)
                     /locus_tag="VU722_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU1772223.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(14648..14887)
                     /locus_tag="VU722_001248"
     CDS             complement(14648..14887)
                     /locus_tag="VU722_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772224.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(15148..16218)
                     /locus_tag="VU722_001249"
     CDS             complement(15148..16218)
                     /locus_tag="VU722_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1772225.1"
                     /translation="MKKLYSFLAGIVAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLEQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKLEGLENIGLEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNAAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDA
                     AYAFINFMLKPENALKNAEYVGYSTPNLPAKELLPEEKKEDKTFYPDAETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(16215..16988)
                     /locus_tag="VU722_001250"
     CDS             complement(16215..16988)
                     /locus_tag="VU722_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772226.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLIVTQTFFLAFLSAFIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTKLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(16985..17791)
                     /locus_tag="VU722_001251"
     CDS             complement(16985..17791)
                     /locus_tag="VU722_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772227.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGHRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(17772..18929)
                     /locus_tag="VU722_001252"
     CDS             complement(17772..18929)
                     /locus_tag="VU722_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772228.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDILLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILSGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(19089..19994)
                     /gene="murB"
                     /locus_tag="VU722_001253"
     CDS             complement(19089..19994)
                     /gene="murB"
                     /locus_tag="VU722_001253"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU1772229.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSSITLEREVRILGESK"
     gene            complement(20106..20858)
                     /locus_tag="VU722_001254"
     CDS             complement(20106..20858)
                     /locus_tag="VU722_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU1772230.1"
                     /translation="MTIHIIIIMLLLLVFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLVYIIYGLAMAAFFEETARLVFFKCLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(20868..21599)
                     /gene="budA"
                     /locus_tag="VU722_001255"
     CDS             complement(20868..21599)
                     /gene="budA"
                     /locus_tag="VU722_001255"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU1772231.1"
                     /translation="MDKNVQEPAKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDTLIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     GGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            21741..23012
                     /locus_tag="VU722_001256"
     CDS             21741..23012
                     /locus_tag="VU722_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU1772232.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKTNQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(23032..23847)
                     /locus_tag="VU722_001257"
     CDS             complement(23032..23847)
                     /locus_tag="VU722_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU1772233.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     CLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(24004..24657)
                     /gene="phoU"
                     /locus_tag="VU722_001258"
     CDS             complement(24004..24657)
                     /gene="phoU"
                     /locus_tag="VU722_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU1772234.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(24669..25427)
                     /gene="pstB"
                     /locus_tag="VU722_001259"
     CDS             complement(24669..25427)
                     /gene="pstB"
                     /locus_tag="VU722_001259"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1772235.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(25440..26243)
                     /gene="pstB"
                     /locus_tag="VU722_001260"
     CDS             complement(25440..26243)
                     /gene="pstB"
                     /locus_tag="VU722_001260"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1772236.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(26254..27138)
                     /gene="pstA"
                     /locus_tag="VU722_001261"
     CDS             complement(26254..27138)
                     /gene="pstA"
                     /locus_tag="VU722_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU1772237.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(27128..28045)
                     /gene="pstC"
                     /locus_tag="VU722_001262"
     CDS             complement(27128..28045)
                     /gene="pstC"
                     /locus_tag="VU722_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU1772238.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(28045..28923)
                     /gene="pstS"
                     /locus_tag="VU722_001263"
     CDS             complement(28045..28923)
                     /gene="pstS"
                     /locus_tag="VU722_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU1772239.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTMLEGRQ"
     gene            complement(29497..30801)
                     /locus_tag="VU722_001264"
     CDS             complement(29497..30801)
                     /locus_tag="VU722_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU1772240.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(30802..31575)
                     /locus_tag="VU722_001265"
     CDS             complement(30802..31575)
                     /locus_tag="VU722_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU1772241.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(31565..31843)
                     /locus_tag="VU722_001266"
     CDS             complement(31565..31843)
                     /locus_tag="VU722_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU1772242.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKEEGKISLGK"
     gene            complement(31843..32244)
                     /locus_tag="VU722_001267"
     CDS             complement(31843..32244)
                     /locus_tag="VU722_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU1772243.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
BASE COUNT         9628 a         7478 c         6202 g         9057 t
ORIGIN      
        1 ttttacctat tttatcataa aaagccagaa attccttaaa aattcctgac tttaggatag
       61 ttattttctt attttagcaa ttctgaaact ggttcgaaaa caattttttc aatgtcagaa
      121 aggtaaattg ccaattgttg ttgcttagta aagaattctg acaagaggct atttccttga
      181 atctgcttgc caaagccttc catcttatct tggaaggacg catctggcat ttgacctgtc
      241 tgtgctagtt tttgaatttc ctcttgaaag gcaagataat ctgtaaagat tttgcttgcc
      301 tcagcatctg ctgcaatcgc atctttagct gctttgacag ccttgtattc tggtaattcg
      361 cgtagaccgc gactaagttc gtttgcacta tcgtaaatat ttgacatgat tttctcctta
      421 tttgacaacg actgtgtagt cggtattttc tgttattaga tgctcagctc tttccaagtc
      481 ttgagcattt ttaaatgaaa tttgtagaat cccgtgaata tcctcacggt tttcctcgtt
      541 gatatgaata ttgaccaagg aagttccacg tagtagttcc aaaatcctca agatgacatc
      601 ttcttcatcg ggaacgtcga catagaggtc gtaagaacta tccacacctc cacgcttatg
      661 gatttccatg gcctgacgtt gctcacgcgc ttggttgaaa aagttccaaa tctgctcttc
      721 atctcccttg ctgatagcct gaccaacctc atccaaccgt tccttgaaat cctcaattcg
      781 ctccagaatg gtctcacgat tagacaagag aatggaagtc cacatacctg gctcactttc
      841 cgcaattcga gtcatatctc ggaaaccacc ggccgcaaag cgccttgcca tctcatgttc
      901 ttgagcatag accgcggtct gttccatgag actagaagcc agaatatgag gaaaatggct
      961 aatctgagaa gtgactcgat catgctcctt ggcatcaatc tcgataaagc gagcatgaag
     1021 acctgaaagc agctccttca tttcctcaag cgtgtcagga cttgtcagac tcgaaggcgt
     1081 gaagatataa taagcatttt caaaaagatt gacatctgcc gaagcagccc ctgtcttgtg
     1141 actaccagcc atgggatggg ctcctacaaa acgaacaggc ttgccagcca aatagttctc
     1201 cgctgcatcc acaatagctg acttggtcga accagcatct gaaataatga caccttcttt
     1261 caagtccaag ttggccaact ccttaataaa ggaaatagtt tgtttaattg gcaagctgag
     1321 aataatgata tctgccaaag gagcaaaact agcaaaatca tccgttgcac ggtcaatcat
     1381 gccttctttc aaggcgatat ctctcgaagc ttgactacga ttataaccta aaatttcata
     1441 atctggatga tcgcgtttga taccaagtgc catagaggct ccaatcaacc caagacctgc
     1501 gatatagatt gtttttgcca taggaactcc ttaatagttc tttgtatagt ctcggtgttt
     1561 ggctaccgct tcttttagtt cctcaagatt atctgatgag aatttttcga ggatttcttg
     1621 cgccagaacc gttgctacaa ctgcttccat gaccattcct gcagctggaa gagcagtcgg
     1681 atcacttctc tccacggttg ccttataagg ttcgtgggtt tcgatatcca cactcataag
     1741 aggtttataa agagtaggaa tgggtttcat gaccccacga acaacgatgg gttgcccatt
     1801 agtcatacca ccttcaaaac cacctagatt attggtacgg cgagtataac cgtcttcttt
     1861 agaccagaga atttcatcca taacttggct acctttacga taaccagcct caaagccaag
     1921 accaaattcc acccctttaa aggcattgat ggagacaaca gcttgagcca atcttgcatc
     1981 caattttcta tcccattgga cataggaacc aagaccaact ggaacgcctc cgacgactgt
     2041 ctccacaacc ccaccgatgg tatcaccatc acgtttgatt ttgtcaatat agtccttgat
     2101 ttcctgtcct cgttcttggt tgacaataga aacttcagac tgggcagctc gttgcttaat
     2161 ttcagcgact gtcagatttt caggaacatc gatttccttg ccaccaaaga ccacgacatg
     2221 gttggcaatc tccatatcca gctcagccaa gaggcgtttg gctactgcac caactgccac
     2281 ccgcatggtg gtttcacgag ctgatgaacg ctccaaagaa tttcgcaaat catcaaaacg
     2341 gtacttaatc cccccaacca aatcggcatg acctgggcga ggatgagtaa ttttccgctt
     2401 gcttttaagg cggtcttcaa tgtcctccgc agacatgatg tccagccatt tctggtggtc
     2461 cttattgatg acatccatag taataggcgc ccctgtcgtc ttcccgtggc gaacgcccga
     2521 agtaaagaca acctggtcac tctcaatctt catacgacca ccacgaccgt agccaccctg
     2581 acggcgtcta aggtcctcat tgatatcctc agctgtcaat ggaagtccag ctggaattcc
     2641 ctcaataata gctgttagac gggggccgtg tgattctcct gcagttaaat atctcataca
     2701 ctctccttat tttaccaagt agtctttcat ctcttccaga gaaactgggt gaatggtcgc
     2761 tgaaccaagc tctggcacca agaccaattt caaggtgtta ccacgcgctt tcttgtcatg
     2821 agtaagagcc tgataaagct tgtcaacttc ccaattttca tagtcaacag gcaagccgaa
     2881 tttctgacac atctctgtga tagattgggt aatgccagct ggcatgaggc ctttttcctc
     2941 agcaaccttg gaaatctgta ccattcccat ggcaacagcc tctccatgca tgaccttgcc
     3001 ataaccggca gtcgcttcga tggcatggcc aatagtgtgg ccaaaattga ggtaaagacg
     3061 aataccattg tccaactcat cttcaaccac catcttgcgc ttcacctgac aagaatgttc
     3121 aatcaaggtc tctgcatgtt ccaaaatgct ctcaacagaa ccattcagcc ccgtcaagag
     3181 agcccacagt tctggatcct caatcaagcc atacttgata acttcaccca tcccttcaat
     3241 caactctctt tttccgaggg tttcaagaac aagtggatca atcagaaccc catctggttg
     3301 ggcaaaggtc cccaccatat ttttagcaaa tggtgtgtta acgcctgtct ttccaccgat
     3361 agaagaatca acctgagctg tcaaactagt cggaatctga acaaagtgaa taccccgcat
     3421 ataggtagag gctacaaagc cagccaggtc cccaacaacg ccaccaccaa gagccacgat
     3481 tccatcgcta cgagtcagac cttgcttgac tagaaattca tagactttct gaacagtagt
     3541 taaattcttt ctttcttcac cttctaagaa atcaaaaaca gctacctgaa agccagcatc
     3601 ttctaggctg agcttgacct tctctgcata gagagaggct acatggttat ctgtcacaat
     3661 gactaccttt tgcggttgcc agagttctcg caaccactga ccagcctggg ccatacaacc
     3721 tttttcaatc tgaatatcat aaggatgatg aggaatatcg attctgattt tcataggaga
     3781 gtctcccttt ctttattgat atttttctgt taaagactgc caaatctctt ctgtcggcat
     3841 ttccttgcct gtccacagtt gaaaagcttc tgcagcttga tagagcaaca ttcccagacc
     3901 attgactgct ggattgccct gacttctagc ccatttcaaa aacggtgttt caaagggttg
     3961 gtatatgata tctgcaacta atagagtttc tggtaagact atgttttcag gaacaggaga
     4021 ggattggcca tccatgccca cactggtggc attaactagc aaatccgact cggcaatcct
     4081 tgcttgcagt tcagaaacat attctaaagc acacaaatcc actttaaagc ctgtctgctc
     4141 ctgtaacttg tctaggtaag gtcttgtttt ttccatagaa acggaacgaa caaagaccga
     4201 aatctgactg acgccatcca aaatagcctg tgccaagatt gatttagccg caccacctgc
     4261 acccagcagg gtcatctttt tacctgaaat tgtaaaagaa ggcaagcact taaaaaatcc
     4321 cttgccatct gtattatatc caattaaatt gccattctca ttgacaaccg tattaaccgc
     4381 accaatcaag cgcgcttcat cgctcagctc atccaaataa ggaatcacct gctccttata
     4441 gggcatggac agattgatgc caaacatctg gtagcgacga atattggcca ctgtttctgc
     4501 caagtcactc gcttcaatct cccaagccac gtaagtaccg ttggtagctg tcgcctcaaa
     4561 ggctctattg tggatgaagg gagaaataga atgcttaata ggattggcaa caactgcagc
     4621 taaacgtgta tagccatcaa gcttcatcca aaatctccct gatttttttc atgctagcta
     4681 gagaaatctg cccaggggca ctaacctcat ccagactggc aaaagaccaa ctcgaaccag
     4741 tcacatccgc agtgatacga gagaccttgc ccaccttacc catagacatg gtcacatatt
     4801 cctgttcagg attgagggtt ttaaagcctc gtgtatagtt catcaagtct aagacatcct
     4861 gctccgtgtg agccatcgcc gcaaccttga caagttttgg atttaggatc gtcaactctg
     4921 acaagatttc catcatgttc tcaggtgttt cttggaaatt atggtaactc aaaacaagat
     4981 ttgggaagcc cagcatttcc tcaaaaacat ccttgtagct atagtactca aaatcaatat
     5041 agtctggttg atagagttgc gcaacttcct tgattagatg gatatactct tctggagaaa
     5101 ggtcgatttc tccaccttcg gaacgagttc gtagcgtgaa aaccaactca cggcctgcga
     5161 atttttcaaa aatggctgga gctacctgca aaatcgcttc tttaggcaga tagtcggcac
     5221 gccattcaat gatgtcggca tccaggtacc tcgtggcatc cagagcctga gcctcctcta
     5281 aacttcttgg cattactgaa acgattaatt tcatttacta accttcatac taatcacctt
     5341 gaggtaatta ctactttcat cttttttatt ataggcaaaa tctgctggaa gaccatattt
     5401 gtttaaaatc tggtaacttc ttcctgcaaa gcctttatca atttgttctg taaatttctg
     5461 acgggaaaca ttggcagcat tggtactggc aatgataatc cctcccggat ttaaaatctc
     5521 aagactctgg gaaatcaact tgtgataatc cttggccaca gagaaagttt gttttttatt
     5581 ccgagcaaag ctaggcggat ctaggacaat cacatcgtag gtcaagtctt tgcgtttggc
     5641 atatttgaaa tactcaaaga catccatgac tataaaacga tgctcgtctg tgctgagccc
     5701 atttgcctga aaatgcgctt gagacaattc tcgtgaacgt ttggctagat caacagaagt
     5761 tgtctggcta gctcctccca tggccgcaac tactgaaaaa gccgctgtgt aggaaaacat
     5821 atttagcaag gatttaccca tagccaagcc gtcaactaaa ctaccgcgaa cctcatgctg
     5881 gtctaggaaa attcctgtca tcaagccatc attcataaag acttgataca ggacaccatt
     5941 ttctaaaaca gtgaaaaagt caggtgcttc ttgaccataa acatgggcag attcatagtc
     6001 caacccctta aagcggattt tctcataagc ccctaaaacc tcagggaaaa cctgtctaaa
     6061 ggcttctgat atagtctgac gaatctgata aacataagag ttataccaag aaaaaacggc
     6121 gtagtcgcca taaaggtcca ctgtcagacc cccaaagcca tctccctctt gattaaagag
     6181 acgaaaggca gttgtcaaat catcttgata gtaggtgctt ctcttttctt tggcttttct
     6241 aaacaaggtt tcaaagaaag cttgattgaa ggccaccttg tctttgctga caaaccagcc
     6301 caagcccttg ttttgctgag aaagataggc agtcccaaga aagtttcctt cctgaccctg
     6361 cacctctact tcctgatcct taagattgac attctcaagt tcactggctt ctagtaaaac
     6421 tagcccctta gcaagcttct tttcaaccct tttgctgact cttattctat tcataactac
     6481 cattatatca aacttttaga caattctcaa aaaagaaact accctttctt ttttactctt
     6541 cttttaaaaa atggtatact agacttcctg caaaactagg aagtaaatgt gtaagaatca
     6601 caataaaaaa tgctcttccg tcttggagga gcttttcttt ttatcaacga aaatcaaatg
     6661 gcaaactatg aaactagcct caggttaact gtgagattat aggtagagag gttgtatcag
     6721 caatatgtgt ctgtcaaatt tagtaacaaa ggtagtagaa gaaagataaa gaaataaatc
     6781 agcttcagta gatatctgga aaatttgatt ttatagagaa gccttttgtt acaaactcaa
     6841 tatactatca ataaataata ttatagaagc aacaataatt ataatttcac ctatctgcat
     6901 aattctattt cgaactctaa atatatgttc tatcaaaaat acttgaaaaa gacacattat
     6961 aggaattaaa gtttttgaaa ttgaaaaata ttcaaataaa taaactataa acaacaaaaa
     7021 tagaactatg ttatatttct tattcaaaac attcctccct atatattttt gattaccaat
     7081 cttaatcatt tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat
     7141 caagcaagcg accaaccagc tcatcttttt tctatttctg ccaatatgcg tgacaggtag
     7201 taatgatagc caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagctg
     7261 atggcaagga taggggagag agactgaacc aagaatatgc tcccaattac aagagccatc
     7321 aggattgcac tataaataaa caataaaact atggcgacta tgccatttga acgattcacc
     7381 aggtccgtaa tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg
     7441 caagaaagga tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg
     7501 gacaagccta gatatagaga aagaccgagt aaagtcagaa ttggtaaaaa ggactgaaca
     7561 gcaaagataa tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc
     7621 agaaaatcaa cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg
     7681 ttattgacaa ctgctataaa gagagctata aaaaacaagg gtaaccagta tggaggatga
     7741 atgtctggaa ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa
     7801 ggaaggaaag cacttgtaaa aagcactgta atcacgccag tcccctgtcc caagagggtg
     7861 aggtggtagc gtaaaaccat acggaaaaag ccctttttaa tagttgaaat cctctccttg
     7921 ctgcgacgtt cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga
     7981 ggaaggacct tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc
     8041 agacccacta aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga
     8101 ggataaagga caaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga
     8161 agaaagaaga taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa
     8221 atagactgat actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc
     8281 actaaagtaa cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc
     8341 caaagagaag gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt
     8401 ccagttagag ctggcaaaag gacagacagt cctttagcaa ttataatctc tgattcttta
     8461 aaagcatagg gactatagga ggccaaatcc ttactctcat aaaaaacatt gtaaaatgca
     8521 gttaaagaag ttgaaaaggc aatcactagt aaaatagcaa ccatgaaact aaaataaaca
     8581 ggcatttcct caaaaggaaa atgaatggct atattactaa aacagatgat catcaagaga
     8641 ctggaaaaaa tgtaagaact taagactcta gcggaaacat ttactttttt cccaggattc
     8701 ttagcctgct tctttcgtag attagccaga ttagcttctt gagatgaata aaggatattg
     8761 atatcaacta attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc
     8821 aagactaagg tagatacttt ccaaagactg gtctgggtaa tcttttctca agtcctctac
     8881 actaccacaa taaatcaaat gccccttttt caaaatggca atccgatcac agacttgctc
     8941 tgccacctct aggacatgag ttgaaaacaa gactgtcttc cctttttgtg catgttcctt
     9001 catcatctgt ttcaaatcaa aggcagcctg gggatccaaa ccagtcaagg gttcatccaa
     9061 gacccaaata tcgggatcag acaagagtgc tccgatgaca aagactttct gacgcattcc
     9121 gtgagaaaga gtttcaataa cctgatagcg attttcagca aaatcaaaaa cgttcaatag
     9181 cctagctaga ctagcctcca agtcagatct actcagatca taggatgagg cgatcaattc
     9241 ccaaaattca ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat
     9301 ctttcgttta atagccaagc gattttccga taactcctga ccgtctacca aaatacgacc
     9361 actgctgggt gaaatgatac tgactaggga ttttatagtg gtcgattttc cagccccatt
     9421 atgaccaatc aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc
     9481 ctctttatca ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc
     9541 tttatctgta ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt
     9601 ttaagtagtt aaaatagttt ccttctatct tacgcaaacg tttgctccga gagatacttt
     9661 atgatagaat aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact
     9721 catgcaatac tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga
     9781 aaatgctcca cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa
     9841 ggcaaccaac gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt
     9901 caaccaaaaa gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat
     9961 tcaagccctt aaagcacagg gaattcaacc catggctgat gtagttctca accacaaggc
    10021 tgctgccgat aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt
    10081 tgaacttgga gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca
    10141 agatacctat aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc
    10201 caaacgcagt aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga
    10261 ggaattggtc gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt
    10321 taaacatcct gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac
    10381 tggtgtagct ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa
    10441 cttcatccgc gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg
    10501 gaacccagac aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct
    10561 tgtcgatgtt cgtctccacc agaatctctt tgatgctagc cgagcaggtt ccaactataa
    10621 ccttcgtggc attttcacag atagcctggt tgaactcaaa cctgacaagg ctgttacctt
    10681 tgtcgacaac cacgataccc aacgaggaca agctcttgaa tctactgttg aagaatggtt
    10741 caaaccagca gcctatgccc tcattctatt acgccaagat gggcttccat gtgtctttta
    10801 cggcgactac tatgggattt cagggcaata tgctcaagaa gatttcaaag aagtccttga
    10861 ccgcctccta accatccgaa aagatttggc ctatggagag caaacagact actttgatga
    10921 tgctaactgt atcggttggg tacgttcagg cgctgaaaat caatccccaa tcgcagtctt
    10981 gatttcaaat gaccaagaaa acagcaagtc aatgtttatc ggccaagaat gggctaaaca
    11041 aacctttgta gatttacttg gaaaccacca aggtcaagtt acaattgatg aggaaggtta
    11101 tggacaattc ccagtctcag ctgcttcggt aagtgtctgg gcaaccaata caatctaata
    11161 gctaatgata atcaagccag gtccaatcgg atttggcttt tttgcattca caaaaagacc
    11221 tacccaaatg gatagatctt tactcgatta caatttacct gctactgcat ccaacaattc
    11281 ttgaatttta gcttggttgc ttcctcctgc catggccatg tctggttttc caccaccacg
    11341 tccatcgacg attggtgcca attctttgac aaggtttcct gcatgaaggt cttttgtctt
    11401 gcttgctaca aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga
    11461 gtagtctttt tgtttccaat tatctgcaaa agtacgaagg gcacctgcat ctgatacaga
    11521 aacttggcta gcaatgtaac ggtgaccgtt gacttccttc acatccttga agatatcgcc
    11581 tgcggctgca gctgcggctt tttctttcaa ttcagcattt tctttttgaa gttgacgaag
    11641 ttgttcttga agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt
    11701 tgctgcgaca gctttaagag cgtcttcttg ttcacggtaa gcttcaaagg cttccttacc
    11761 agtcactgcc aagatacggc gagttcctga tccaatccct tcttctttga caatcttgaa
    11821 aagaccaatt tcagaagtgt tgccaacgtg ggtaccacca caaagctcga tagagtagtc
    11881 accgatagta acaacacgga cttccttacc gtatttctca ccaaagagag ccatagctcc
    11941 catttcttta gcagtgtcaa tatccgtttc aactgtcttc acttcaagag cttcccagat
    12001 tttctcgttg acttgctgtt caatcgcacg caattcttca gcagttactg cttggaaatg
    12061 cgtaaagtca aagcgaagga attcaacttc gttaagagat cctgcttgtg ttgcgtgatt
    12121 tccaaggata ttgtgaaggg cagcgtgaag caagtgagtc gcagtatggt ttttcatgac
    12181 acggtgacga cgatttgtat caattaccaa ggtatattct tggttcaagg caagcggtgc
    12241 aaggacttca actgtatgaa gagcttgtcc gtttggagct ttctgaacat tggtcacagt
    12301 agccacgacc ttacctgacg cattcaagat ttgtccatgg tcagctacct gtccgcccat
    12361 ttcagcatag aatggcgttt ccgcaaagat aagtgaggca gttccttctg atacagcttc
    12421 tacttctgca ttgtccgcca cgatagctac caatttagaa gacaattggc tagcattgta
    12481 gttgaagaca ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagct
    12541 acccttgaca gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc
    12601 ttcacggtct acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa
    12661 tccgtatgta tcatagagtt taaagacatc ttgaccagca atgacagatt gacctttttc
    12721 tttcaagtct gccacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa
    12781 tgattcttct tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg
    12841 gtagtagctt tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt
    12901 gatacccaat ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc
    12961 acgaccttca tttcctggaa gggcaccatc accgatagca aatgaaagag aacgaatgtg
    13021 gtctgcgata accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa
    13081 tttctcgact tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc
    13141 ttggataaca gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa
    13201 ttccttgtat tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt
    13261 ccagatttca atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt
    13321 ttctgggtca aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc
    13381 cgcaccgatt tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac
    13441 ttcaatccag cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc
    13501 agcagggaaa tcaaaccatt cagggcttgt caaaagctca taagcccaag tgatagcttc
    13561 gtcacggaag taatccccga tagagaagtt ccccagcatt tcaaacatgg tatggtgacg
    13621 cgcagtcttc cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat
    13681 acgtggattt tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga
    13741 gttgatccac aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga
    13801 gtgacctttg gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg
    13861 tttcatattg tctccttatt cacttgttta atgtgattgg ctttccagca tttccacata
    13921 gtcaatcgcg acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac
    13981 ggtataggta gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg
    14041 atcatccagc aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt
    14101 atcaaactca tacttatctc gccagaaggt caacttctta cgaatgacaa aactcgagcc
    14161 atcccgaagc tgaatctcaa aacgaggaag caaggtcaag atttctttac taatctcact
    14221 gacttgttca ccagccgcat catagatggt aaaggtttta ggaatcttaa aaaatgatcc
    14281 ctccacctga taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag
    14341 acgaaacttt tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag
    14401 ctcatatcac gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct
    14461 cttgttctta tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag
    14521 caccgccatt tctctggact aagacaagtg aaaatcaatt ctcaactctc ttattataac
    14581 gtttttttaa gcttgcgtca actggaaatg atctccgttg aattagacca attccctaca
    14641 tctctgatta ctttttcagg atatattttt tcttactgcc atttttcttt ttatcccaaa
    14701 ttttcatatt actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc
    14761 aatatatgga ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta
    14821 taacagtttg gttaacaatc ataaaggttg gccagaaact ttttttgaaa aaagtagaca
    14881 ttttcattat ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa
    14941 ctaggaagct agcctcaagc tgtacttgag tacggcaagg caacgctgac atggtttgaa
    15001 gagtataggc ttagtatact actaggcaag caaataagca aataagcaaa taaacaacta
    15061 gaatagaaaa agatagggct ctaaaaactg acttctattc cttaaaaacg aaccagcttg
    15121 actgattcgt cttcttacgt ttatctccta cttccgatac attttaaact gtaggaagag
    15181 gtcgctatat tttcctgtcc atttatggtc aaatttctca taaacctcta ggtgtttcat
    15241 ggtttcagca tcaggataga aggtcttgtc ttcttttttc tcctctggga gtaattcctt
    15301 agctggtagg tttggtgttg aatagccgac atactccgca tttttgagag cattttcggg
    15361 tttcaacata aagttgataa aggcataggc tgcatcttgg tttttgactg ttttgggaat
    15421 gaccatattg tcaaaccaaa ggttgctggc ttctgtcggt accacatagc gtagattttc
    15481 atttttttct agcatttggc tagcttcccc agagaaggtc acaccgatgg cagcattgtt
    15541 ctgaatcatg tagcccttca tctcgtcggc aacgatagcc ttgatatttg gagtcaattt
    15601 atagagctta tctactgtct cttccaactg ctgtggatcc ttggagttga ggctgtaacc
    15661 aagggaatta agtcctagtc ccagcacctc acgcgcccca tcaaagagca taatagagtt
    15721 cttatactct ggcttccaga ggtcatccca gtgctcaggc gcttcatcta ccatagtttc
    15781 attgtagaca attcccaggg ttccccagaa gtaagggata gagaatttat ttcctgggtc
    15841 aaaggactgg ttgaggaact ctaatccgat attttcaaga ccttcaagtt ttgaatagtc
    15901 aagcggtact aagaggtctt cgtccttcat cttgttaatc atgtattcac taggaatggc
    15961 aatatcgtag gtcgttccac cctgcttgat cttggtatac atggcttcgt tggagtcaaa
    16021 ggtctcatac tggacttgga tgcctgtttc ttctgtaaat tgctccaaga gttctggatc
    16081 gatatagtcc ccccagttgt agataaccag tttttgacta tctcgactat tgattttact
    16141 atcgagatga gtcgcaattc cccacaagac gaggataatg gctacaattc ctgctaaaaa
    16201 tgaatagagt tttttcatgc ttgctcctcc ttctcacgtg agataaagta atatccaaca
    16261 actaggataa tactaaagag aaagacaagg gcagacaggg cattgatttc tagcgaaatc
    16321 cccttacgag cacgagagta aatctcgact gacagggttg aaaagccatt tcccgttaca
    16381 aagaaggtca cagcaaagtc atctagcgaa taggtgaagg ccatgaaata accagcaatg
    16441 atagatggag tcaggtaagg aagcataatt tccttgaaca tctgaaattg actggcacca
    16501 aggtcatagg ccgcatgaat catatcgcca ttcatttcct tgagacgagg caagaccatc
    16561 aagaccacga taggaatgga gaaggccacg tgactagata gaacggtcaa aaagccaagt
    16621 gaaaacttga gtttggtaaa gaggatcaag aaactggcac caatcataac gtcaggcgca
    16681 accatgagga tattattgag tgaaagaaag gcttcttgat atttcttacg agactggtag
    16741 atgtaaatag caccgaaagt cccgataatg gtcgcaataa aggctgataa aaaggccaag
    16801 aaaaaggttt gagtcacaat taacataagg cgaccatcgc caaacatggt ttcaaagtga
    16861 gtccagctaa aacctgtaaa gctattcata tcatcaccag cattaaaggc atagccaatc
    16921 aaataaaaaa tcggcaggta gaggacaaga aagaccagtc ctagataaag gttggcaaat
    16981 tttttcatcg ttctctcctt tccttggtca cccacatggt gatgaacatg gtcaagatga
    17041 gaattacacc gatggttgaa cccataccgt agttgtcatt ggttaggaaa ttctgttcaa
    17101 tagccgtccc caaggtgata acgcggtgcc caccaatcaa acgggtcagc atgaagagac
    17161 tcaaacttgg gataaagacg gattgaaccc cacttctcac accgttcatc gatagaggga
    17221 agatgacatg acggaaggtc tcccacttgg tcgcaccgag gtcatagctg gcattgatga
    17281 gattgttatc catatcgtcc aagacattga aaatcggcaa aatcataaag ggaagctcga
    17341 tgtagcttgc gacaaagata aaggagaaat cggtaaagag caactgttgc gaaccaattc
    17401 cgataaattc caagaattga ttaatagagc cattctgacc aaaaatcccg ataaaggcat
    17461 aggctttaag gagcaaattg atccaggttg gcaggataat cagcatgagc cagagttgac
    17521 ggtgcttgag acgggtcaaa aagagggctg tcggatagct gataagcaag gtcacaaagg
    17581 ttacaatccc tgcatagagt acagagttga aactcatttt taggtaggtc aagttttgtg
    17641 acgcaaagta agatttgtaa ttttctaaac tgaactggcc ttcgatgttg aaaaaggatt
    17701 gaccgaaaat caagaccaag ggtgccagaa caaagagggc aatccaaagc atgtagggca
    17761 ctacaaagag tttagagctt gttttcttca tctctttcct cctcgattgc attgatcaaa
    17821 cctgcttctt gctcttcgat ttccacgtat tcttcgatac gagcatcgaa ctcttcttct
    17881 gtttcgttga gacgcatgat atggatgtct tctggttcaa agtccagacc gatttcctca
    17941 ccaacaatag ccttacgggt tgagtggatc atccattcat tcccaagctc gtcataggcg
    18001 ataatttcat agtgaactcc acggaagagc tgggtatcca ccttaacttg gagcttgcct
    18061 tcttcaggaa gggtaatgcg caagtcctct ggacgaataa cgacctcaac aggttcattt
    18121 ggcttcatcc ccccatcgac tgcttcgaag cgtttgccgt taaattcgac caagtagtcc
    18181 tcaatcatgg ttcctgacaa gatatttgac tcgccgataa aggtggcaac aaagtgattg
    18241 attggctcat cgtagatatc tactggtgtt ccagactgaa caatctcgcc atcattcata
    18301 acgaaaatcc agtcactcat ggccagcgct tcttcctgat catgagtaac aaaaacaaag
    18361 gtgattccca atcgttgttg cagttcacgc agttcgtact gcatgtctgt tcgtaatttt
    18421 aagtccagcg ctgacagagg ttcgtccaac aacaccacac ggggttggtt gatgatggca
    18481 cgggcaatag ccacacgctg acgttgtcct ccagaaagtt tgcggatgga acgtttttca
    18541 tacccttcca actgaaccat cttgagaact tccgctacgc gttgctcgat ttctttcttg
    18601 tcaattttac gcaagcgaag tggaaaggca acattttcaa acacattcat atgcggaaac
    18661 aaggcataag attggaaaac ggtatggacg tctcgcttgt tggttgggat gtcattgata
    18721 cggacaccat ccagcaaaat atctcctgtc gtcgcatcca gtaaccctgc aataatgttt
    18781 aggatggttg atttccccga accagatgca cctagaaggg tgtagaattt tccttcttcc
    18841 aactcaaagt tgatgtcttt gagaaccttg gtgttgctgt cttcaaaaac tttagagacg
    18901 tttttgaatt cgataattgg ttttttcaat tggcataaat tccttctttt tcatagatta
    18961 accgatcggg gctctgtcag gtccccacta cctcttgcag ggagtaaaac cacctgcata
    19021 catcttcgct accgataggc tttcaccccc tttccatgac atagcagcag cttttcaaat
    19081 acagcttcct acttgctttc acccaagatc cggacttctc tttcaagcgt aatacttgag
    19141 tgttccttaa ctttttcgat aaccgattgg atcaagtcct cgtagtcttt ggccgttcca
    19201 tctgcgacat tgatcataaa tcctgcatgc ttttctgaca cttctacgcc accgatacga
    19261 tagcctttca agccagcttc tgaaattaac tgacctgcaa aatgcccgac tggacgctta
    19321 aagaccgagc cacaagatgg gtattccaaa ggttgcttga gttcacgtag gtgcgtcaag
    19381 cggtccattt cctgcttgat aacctgatgg gttcctgggg ctagggcaaa tttaactgac
    19441 aagacaactg caccagactc ctgaatagct gaatggcggt aaccaaaagc caagtcttta
    19501 gcagacaggg tttcgatttc tccatccttg gtcaagacct tacaagactg caagatgtga
    19561 gcaatctcgc caccataggc acccgcattc ataaagacag caccgccaac gcttcctgga
    19621 ataccacaag caaactcaaa gccagtcaaa ctatgacgga gggcaatgcg agttgtttca
    19681 atcaagttag ccccagcttc tgcttcaatg gtatagccat caacagaaac gttattgagc
    19741 ttgtcacaca agatgacaaa tccacgaatc ccaccatcac gaacaatgat attgcttgca
    19801 ttaccaagaa ccatccaagg gatattttct tggttggcaa atttcacaac gcgagccaac
    19861 tcaaaacgat ttcgtggaaa gaccaaataa tcagcctctc cacctacttt tgtataacta
    19921 tagctatgca agggttcctt aaaacggata tcaattcctt ctaagatttc aagcattttt
    19981 tctcttacag acatgtcact cttcctttta caaaattcat tccattatac catttttaga
    20041 gacatttgac gaccataaaa ataccttgtt tggattttgc ataagaaaaa gaggttcccc
    20101 cctttttatg attttttaca aaagatttcc ttggttccat aggcgaccag aacgagctcc
    20161 agtgctagaa tcacttcaac caagactgga tttgtcaacc agcctacttg ggaaagagat
    20221 ggtgccagat caaagaaggc atgcaagcca taggctgcta ggagataaat ccatttcttc
    20281 tggcgaacag cttggtaaac ccaaactgtc aaaagtaatt ggaaaccaag cgccaagatt
    20341 cgctcaaaac caagcaaata aatctgccag accgaaagtg actgaatggt ttttaacata
    20401 ttttcagaca gtaattgcat aacctgtgga ttctgagttt gaactgccga aagaacaatg
    20461 taaagattga gtaaactagt aaggcctaga aaaatcaact ccaagccacc atgcccaagt
    20521 ccataggcca aggcgtctgc cttttccaaa cttctctttt tctccaagca tttgaagaaa
    20581 acaagacgag ccgtttcctc aaaaaatgct gccatggcta ggccataaat aatatagaca
    20641 agcggatgat cttgcaagag ggcaatacta ccgtcttttt gaggatgcaa aatcaagata
    20701 tgcaccagtt tttccaaaat ctgcgaagag acaaagaaag cgactgcacc caagcccaag
    20761 acagctagat taatctggta tttctttttg gcaaaccaaa tgcttcctat cagaaaaact
    20821 agcaacagca acatgataat aatgatatga atggtcattt tcttctccta ttctgccttt
    20881 tcaatatctt ttttcatctc gtcaacattg aacttagcaa acaagtattg acggtcttgg
    20941 actgggaaac gttggtccaa ctggtcaact gctcccacct cgataatgcc ttccttgatg
    21001 acaaaatcca tgacatgtcc accgaaggtc aaatcatctg atatgaagtg cagatggtag
    21061 cctgccacac tgaccccatg gaaaatctca ggcgtccaga aaccaacaat agtcccccca
    21121 acattgtcac gactatattc cggttgatgg gttgcgacat cagcaaactt ggtatcgggt
    21181 gttgacttag gaatcatacg cacatgcata tgtgaaaatt ctccccgaat cttgatagaa
    21241 cggaaaagat tttccccatc ataataagac tcaattcgtt cttccaattc cttgtctgtc
    21301 atctcaaagc gctggcggaa aatgacctct gcctgatgcg gtactactgc tgcataagga
    21361 ataagggtat ctggtgacac ttccacaatt tctggctgtt ctcctgttcc ttttgcctga
    21421 taagccttgc catctaagac aatcaattcc ccatcaatag aatccaaggt tcccaaacca
    21481 aggtcaccat gctctagcaa ttctcccact gtcatggtac caccataaag gccagccatc
    21541 aaggctccaa gagtattgta ttgaaataat ttcgctggtt cctgcacgtt cttatccatt
    21601 cactttcttg tctgttattc tataaatgtt actcctaagt ataccacatt tgcccctaga
    21661 tgtgaacgag agaaacgctc tagacattgc caagaaggaa aaaaaagggt acaatgtaac
    21721 aaaatcaagg gaggtctgga atgaagaaac aaagcaagta caaagaggtc gtttcctatc
    21781 tgaaaaatgg tatcgagtct ggacgatttc cgacgggtag tcgcctgcct tctatccgtc
    21841 aactgagcct tgactttcac tgcagcaagg acaccattca acgagccctg ctggaattac
    21901 ggcacgaaca atacctctat gccaagcctc agagtggcta ctatgtatta gaacaagggc
    21961 aacatcaaga cctagaaatc gaggttaccg acgaacatgc cagtgcctat gacgatttcc
    22021 gactctgtgt caatgaaacc ttgattggcc gagaaaacta cctcttcaac tactatgaca
    22081 atcaagaagg attagaagac ctaagacaat ccattcacaa actcctcttt gaccaagctc
    22141 tctactgcaa gactaaccaa ctagtactga cttctggaac ccagcaagcc ttgtttatcc
    22201 tatctcaaat atcctttcct agccaagcca aggaaatctt ggtggaacag ccaacctacc
    22261 atcggatgaa tcgcctcttg attgcacagg ggctggacta tcaaacgatt gaacgaggca
    22321 ttgatgggat tgacttggag gagctggaag gccacttcaa aacaggaaaa attaaatttt
    22381 tctacaccat tccccgattt cactatcctc tgggacattc ctattctgag caagacaaac
    22441 gatctattct taacttagct gccaagtatg atgtctatat cgtagaggac gattatctgg
    22501 gtgatttgga ctccaagaag ggccaaacct tccactatct tgatacagag gagcatgtta
    22561 tttatatcaa gtccttctcg accagccttt ttcctgccct tcgtattaca gcactcattc
    22621 ttccaaatgc tatcaaagaa gcatttgtgg cctacaaaaa tatcctagac tacgacagca
    22681 acctcattat gcaaaaggcc ctgtcactct atattgacag tcaattgttt gaaaaaaatc
    22741 gtttggctcg cttgaccaat catgaatctt accaaaaaca aatcgaagaa aggataacta
    22801 aaacaccttg tcccctccct cattatcccc tacacgatgg tttattgcta gacctgagac
    22861 agtatcctaa aatcgccagt ctcaaacaca gtcaactggg cttggacttc tttgaagagg
    22921 cctatttaag cacctgtcct tatcaatttg ccaaggtgtc cctagacaat ctggaaaatg
    22981 ttttaaacta tttaaaagca gaattggaat gacatccaac tctgcttttt cttattcttc
    23041 aacttcagtt agacttgctg ctttttcaag atagctttgg taagttcctt catccttaag
    23101 tttttggata accttgtcta ccacttcttt caaatcatca ctattttttc taagagcaac
    23161 ggcattggcg tcgccgtcct tcatcttcaa gcagacagtt gcgacagcta agccagcgtt
    23221 tttagcagca taactaagtg caacaggttc atccatatga acagcatcta cttttccagc
    23281 ctgcaattca ttgactgctt cacccatatt agttagggaa gttaattgag cttttggcaa
    23341 ttgttccttg accattgatt ctggaacagt ccctttttgg gctgcaatat tagcactttc
    23401 taggctagtt aaatccttgt atttttccac atcagcctta cgaaccaaga aactaatctt
    23461 gttttcatag tatgggattg aaaaatcaaa gacttctttt ctctcgtcag tagcactaat
    23521 tcctgcaact gctaggtcag ccttaccagt ttgaagactg gtcaaaacat tgtcaaaact
    23581 catgcttgag atttccaact taaccccaag ttcatcagcg atagcctgag ccatgtcgat
    23641 gtctgcaccg actacctggt tctttccatc aaccaatgat tgaaattcaa agggtgcata
    23701 gtcaggactg gttgccacaa ctaatttccc cttttgctta atggcctcaa cagctgactg
    23761 agaaccatta gaacctgact ggcaagctac taagaagaaa cttgcaagaa aattacataa
    23821 aacaaatatc catttttttg atttcataaa taaacaacct ctctgttaat tttgtataat
    23881 tataacgata tccaagttac ttgtcaagtg ttttttaaat ttttatctca aaaatatttt
    23941 tttgttcaaa aaaaggagcc atcagttgat tccaagctcc tttttataca gaattaaact
    24001 attttatagt tcgacaatct tacctgtttc aaagtagaca acccattcac agatattttt
    24061 agcatagtca ccgatacgct ccaagtagga aataacttgg aaataatcac gacccgtaac
    24121 aatggcttct ggatttttct taatctcttc agtcgcaagg tcacggatag tttcaaaata
    24181 gtggttaatt tgctcatcca tggaggccac ccggtatgcg tcgtcaacag aaccattaag
    24241 ataaagatca agtgctgctt caacaacgct tttaacttca cgtcccattt ttttaatttc
    24301 ttcctctaca gctgggatgc gttcttcccc cttcatacgg atggttgcct gggcaatggc
    24361 tacagcgtga tcccccatac gctccacatc tgatacagcc ttaaggacag tcaagactgt
    24421 acgcaaatct tgagagactg gttgttggag tgcgatcatt tcaaatgatt tcttttccag
    24481 tttcacttcg tattcattta cttctgcatc atcttcgatg acctcttttg ccaggtcacg
    24541 gtcatgcgtg acaaaagcac gtaccgtacg attgatttgt gagagcactt cttgtcccat
    24601 agcgtagaac tggttatgta atttctctaa atcttcttca aattgagatc gtaacatctt
    24661 tcatctcctt atccaaattt tcctgtaata tagtcttccg tttccttgtg ttggggatca
    24721 aggaacatct gcttggtatc attaaattca atcaaatctc catctaggaa aaatcctgtc
    24781 ttatcagaga tacgtgaagc ttgctgcatg gaacgggtta ccagaagcat ggtgtacttg
    24841 tcttttagac catacaaggt ttcctcaatt ttaccagctg aaatcggatc caaagccgaa
    24901 gttggctcat ccaagaggat gattttagga ctagttgcca agacacgggc cacgcagaca
    24961 cgctgctgtt gaccacctga caatccaata gctgaatcat atagacgatc cttgacctca
    25021 tcccagatag aggcaccttg caaggctttt tctacggctt catccagaac ctgcttatcc
    25081 ttaattccat tgatacgaag cccgtagaca acattctcat agatagtcat agggaaagga
    25141 ttaggttgtt ggaaaaccat tccgatttcc ttacgtaatt caaccgtatc tgtacgcgga
    25201 ctgtagatgt tgtgaccatt gtacaccacg gatccagttg tggtcacctc tggattgaga
    25261 tctcccatgc ggttaagaga cttgaggagg gttgacttcc ctgatccaga tggaccaatc
    25321 aaggctgtaa tttccttagg ttggaaagat agggaaacac tattcaaagc cttcttttta
    25381 ttataataaa cggacaggtc tgatacctgt aaaatcgcat ctgtcatacg gtttcctttc
    25441 taaccaaagt gaccagatac atagtcattg gtggactgta gcttggcatt ttggaaaata
    25501 gttgcagtct tgtcatactc aatcaaatca cccaagtaaa agaagcctgt atagtcactt
    25561 gcacgagcag cctgctgcat attatgcgtt acaatgatga tggtaaagtt tttcttgagc
    25621 tcaaacatgg tctcttctag ttgcatggtc gcaatcggat ccaaggctga ggctggctca
    25681 tccattaaga ggatatctgg cttaacagag atggcacgag cgatacagag acgttgttgc
    25741 tgaccacctg ataaggtcaa ggctgacttg tggagatcgt ctttaacctg atcccagagg
    25801 gcagcctgac gaagggaggt ttctacgatt tcatctagga cttgcttatc cttaactcca
    25861 gcacgttcat gcgcaaaggt aatattacgg taaattgact tagcaaatgg attggggcgt
    25921 tgaaaaacca ttccaatgtg tttacgcatt tcataaacgt tgatttctgg acggttgaca
    25981 tcaattccac gatagagaat ctgcccagtt actttagcaa tatcaatagt atcattcatg
    26041 cgattgagac tgcgtaagta ggtagatttc cccgatcccg acggaccaat caaagctgta
    26101 attttatttc tttcaaattg catatcaatc cccttaatgg attcattttt accatagtaa
    26161 acatggacat ccttagtaga aagggctact ttttcttcag gaaaggtaag gatatgcttc
    26221 tcatcccagt tatatgttga catggcttct cctttaggca gcggttaatt tcttgtgtag
    26281 atagcttccg aacttacgag ctccaaagtt aaaaatcagg ataaagatca ggagcacagc
    26341 ggcagaacct gctgatacaa ttgttccatc tggaatagtg ccttcactat tgactttcca
    26401 gatatggaca gccaaggttt ctgcttgacg gaagatagag atggggctag tcacactgag
    26461 gatattccag ttagaccagt caagagctgg cgccgattgc cctgctgtat agatcagagc
    26521 tgcagcttcg ccaaagatac gaccagatgc caagacgaca cccgttacaa tacctggaag
    26581 cgcttctgga ataacaacat gaaccactgt ctcccagcga gaaatcccaa gagccagacc
    26641 agcctcacgt tgggtatggt gaacgtgttt caaactatcc tctacattac gcgtcatctg
    26701 aggcaagtta aagactgtca aggccaaggc acctgaaatg attgaaaatc catactcaaa
    26761 ctggactaca aagatcaagt aaccaaagag acccaccacc actgatggta aagaggacaa
    26821 gatttcaata caagtccgca caaagttggt aacaggacct tttttagcat attcagccaa
    26881 gtaaatccca gctcccatag aaagaggtac agaaataatc aaggtaatga ccaatagaaa
    26941 aaaggaattg taaagctgaa tgccaatccc accacctgct tgaaaagcag aagaccttcc
    27001 agtcaagaaa gaccaagaga tatggggcaa gccccgaacc aagatataga gaatcaagga
    27061 agccaagatt gtcacaatga tgctagcaat cgtatagagg acagctgttg caagtttatc
    27121 taatttctta gcgcgcataa tttttctttc ctctttcttt cgtaatcaat ttaatcacac
    27181 tgttaaaaac taaactcatc aagagcagta ccaaggccag tgaccagaga acattattat
    27241 ttacagttcc catgacagtg ttcccaattc ccatagttaa tatagaagtt aaagttgcag
    27301 ctggtgtggt caaggaagtt gggataacag ctgagtttcc gacaaccatc tggatagcta
    27361 gagcctcacc aaaggcacgc gccatcccaa agaccactgc agtgaaaata ccagaacggg
    27421 ccgccttcaa gatcacacgc cagatagtct gccagcgagt agctcccata gcgaaactgg
    27481 cctcacgata ataacgagga accgcacgca agctatccgt tgtcataaag gttacggtcg
    27541 gcaaaatcat gacaaagagg acggaaatcc ctgacaaaat cccaaaacca gtcccaccaa
    27601 agacactgcg aacaaaggga acgacgactt gcaagccaat aaatccgtac actactgaag
    27661 gaatcccaac caggagttca atagctggtt gcaaaatctt cgcccctttt ggtgatactt
    27721 cggtcataaa aactgctgca ccaatagcaa agggtgttgc gataagggct gagagaatgg
    27781 taacgataaa ggaacccaaa atcataggaa gggcaccaaa ttctttacta gaaggattcc
    27841 aagttcctcc caaaagaaag tcaaagatat tcacaccatt gacaaagaag gtcgacaagc
    27901 ctttttgcgc tacgaaaacc aaaatcatgg ccacaaggat gactatcaaa gaaagacagg
    27961 caaaggtcaa accttttcct aatttctcca gacgagaatt ctttgatgga agcaacattt
    28021 tcttagctaa ttcttcttga ttcattattg tctcccttcc aacattgtca cagttccggc
    28081 agcatctttt tcaaccttca tttccttaat cggaatatac ttcaatcctt tgacaatccc
    28141 ttcttgggtc tcatccgaga gaacaaaatt gagaaattct gcagccaact cattgggctg
    28201 ccccaatgta tacatatgct cataagacca caagggccaa ttattgctac ttatattttc
    28261 tggacttaag tcatagccat tcaacttcat gcttttgacc gaatcatcta tataggtaag
    28321 agataaataa gagatagctc ctggactttt tgatacgatt gattttaccg ctccatttga
    28381 atcctgctcc tgactttgca tggcagactg accttccata atgacagtat caaaggtagc
    28441 acgagagcca gagccggctg cccgattgat aacagagatg ggtaagtcct taccaccaac
    28501 ctctttccaa ttggttacct cacctatgaa gatttgacga agttgctctg tcgttaggtt
    28561 atcaacatca acctccttat tgacaatcag agccaagcca gctaccgcga ccttgtggtc
    28621 aacaagagca gaagcatcaa ttccgtcttt ttcctcagca aatacatctg agtttcctat
    28681 atcaactgcc ccagactgaa cctgggacaa gcctgtacca gaacctcccc cttggacatt
    28741 gaccgttttt ccaacatgga tcgtgccaaa ttcatctgcc gctacttcaa ccaagggttg
    28801 caaggcagtt gagccaacag ccgttatgga ttctccacga tcaatccagc tagcacagcc
    28861 tactaaacaa gccgtcagcc aaaaagcgat aagagacaga gcaagctttt ttcttttttt
    28921 cactgttttt ctcctcgaaa ataattatga atactgtgaa ttttttaagt agttctttat
    28981 gagttgacgc atgaattctt accaaatttc tgcgcaattg attatttata taatataggc
    29041 tatattactc tttcctaacc tccttttttc atatgtggat aaaatctctt gtctatccct
    29101 tcccccattg tcacccatta tagtcatttc gtgtctcttt ttcccctttt taatgcaagg
    29161 gaaattactc tcctcagatg ataatccaaa agctagaaag gtatctcaaa cctctctact
    29221 ctcccagact agtttacaac taaaaggaaa agattctatt ttatgagaaa tctagtttac
    29281 aagcggtaag aacgctaata actaaacttc ttgtactctt tgaaaatctc ttcaaaccag
    29341 tgttttgagc tatctatggc tagcttccta gtttgctctt tgattttcat cgagtagtaa
    29401 aactacatgt gatggcaatc aagatatcaa gaatcatcct actaaaaaaa tccatacttt
    29461 cactataaca tagaataaga tatttgacta gcattttcat ttgaatctga ggccttttgg
    29521 aaaataattt ttcaaaacat ttccagtaac ctttgcaaag cccaagccat tgcctttaac
    29581 caaaacttgg taccaaccat ttggcagact ttctgccagc tgaacggttt ctccagccgc
    29641 atacttgaca aacgcttctt ggccaatttc aaccgactgt tcgacctgac tcggtttcaa
    29701 ggctaaacca agagcgaaac tgggctcaaa gcgtttcttc ttaaaagtgc ccagatgcag
    29761 tccattgcga gcaatcttga gcttccctaa atctggcaaa agttctggca agagataaag
    29821 ctggtctcca aaagtctgca agatacccgg tagattgacc ttcaaatggt tttgggcaaa
    29881 ttcctgccac aaggcaactt gttcacggct gaggttactc ttacttgcct taaatttagg
    29941 agctggattg ttacccttaa actgtagatg ggcaacaaac tgaccctctc ccttaaactg
    30001 atgagggtac atccgagccg tttctggcag gtcaatacca gctaccattc cattgatatg
    30061 ctctactggc aacaagtcaa aatcatactc ttccagcaac caattgacaa tctcttcgtt
    30121 ttcctcgggt gcccaggtac aggtcgaata aaccagacga ccaccttcag ctaacatggt
    30181 cactgcatcc tccagaattt ctctttgcaa gctagcacat tgactcggat aatctaagct
    30241 ccaatagtcc atagcatcag gctgcttacg aaacattcct tcaccagagc aaggggcatc
    30301 aagaacgatt aagtcaaaat agcctttaaa gaccttgacc aagcggtcgg cagattcatt
    30361 ggtcaccacg acatttgtcg ctccaaaacg ctccatgttt tcaaccaaaa tcttagcccg
    30421 tttgcttgaa atttcattgg aaacaagtag cccctcccct gctagatagg ctgccagttg
    30481 agttgatttg ccccccggtg cagcagccaa gtccaagacc ttcataccag gactgggttg
    30541 ggctacttga gccaccattt gagcagcagg ttcttgcgaa taaactaaac ctgtagcatg
    30601 ctcaggcgat ttccctgaaa ccttcccata gtggccccaa ggggtttgag taatggcatc
    30661 agaaaaggaa agttgctctt cttttaaggg attgacccga aaggccgaaa ccgcttcctc
    30721 ctcaaaagag gcaagaaaat ctcttgcctc atctcctagt atttctttat atttttcaac
    30781 aaatccttct ggaaattgca tttaagttct tttcctttcg taaatatagg actgaatttc
    30841 ctcctgcatc tcaagaggca ccatcatgac aggctgtctg gtttgaaaat caggagcttc
    30901 accaaaaagg gtcacaaccc gatagcccag actttcccct aaaatactag ctgcggcata
    30961 atcccatggt tgcagataag tgagataggt caacaaacgc cctgacaaaa tcttggcaaa
    31021 actaatggcc gcacttccat agacacgaac accaagaacc gctcggctca aatcagccag
    31081 cccccattca ttggtttcca gcataccact attccctgca atgagaaaat ctccaagtgg
    31141 tttagtttta aaaggagcta ggggcctatc atttagacaa actggaaatt ccccaccacc
    31201 gtggtaacaa tcccctttga ccacatcata aatcagacca aactgtccct gaccattttc
    31261 aaaataagcc atcataacag caaaatcttc ctgctgggct acaaaattat tggtaccatc
    31321 aatgggatca atgacccaaa ccttgccctc ttgaaccgag gctcgcagac aaccttcttc
    31381 agcacaaatc ttatcctcag gataacggga caaaatctca ccaaccaaga gttcctgaac
    31441 ttctttgtcc agtctggtca ccaaatctgt tggagaggac ttggtttcaa cacgcaagtc
    31501 ttcctgcata tggtcaagaa tgtactgacc tgctttctta acaagctctt tagcaaattc
    31561 aaatttactt tccaagagaa atctttcctt cctctttttc tttggcagcc tgaactgctc
    31621 ggtaaagtga atagccacta accgtttcaa attctcgtcc caaacgtttc tcttcgctct
    31681 tgcttggcac gaccgctttg aatcccttat aggagtccag taacttttta gcctctactt
    31741 tgccttcata ggcagcttca acatcattaa aaaaagaaag cactgaagca agttcttcag
    31801 tgctccacga caaatctagt gggtaactat actgtttgtt cattaactaa taccagctct
    31861 cattcttgct tcttttagtt cttgcttacg ataactacga gggagaaaag cacgaatctc
    31921 atcttcatta aaaccgattt gcatacgctt ggcatcaata ataattggac gacgcaaaag
    31981 actaggatac tgctcaatca aatgaagcaa ttccgatacc gaaatactct ctacatcaat
    32041 attcaatttt tgaaaaattt ttgaacgagt tgaaatgatg tcatcagtac cattttcggt
    32101 caaggaaagg atgtgttgca attcttttct tgttaaagga ctggtcataa tattgtgttc
    32161 cacaaaggga accttatgtt tttctaacca ggccttagcc ttacgacatg atgtacagct
    32221 cggtgataga aatagtgtaa tcatgctttt ctcttcttat ctatactttg ctacttctat
    32281 tatacaaaaa aataaggcgc ttgactaggg atttttagaa aaaaagccta ttttttcaag
    32341 aaaaataggc tgtttgcgaa cgatt
//
LOCUS       DAVFJR010000022        31457 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVFJR010000022 DAVFJR010000000
VERSION     DAVFJR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.023"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            161..2416
                     /locus_tag="VU722_001268"
     CDS             161..2416
                     /locus_tag="VU722_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU1772244.1"
                     /translation="MLGAGIALGYGVALFDKVRVPQTEELVNQVKDISSISEITYSDG
                     TVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAVIRATLGKFVGL
                     GSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEILTTYLNVAPFG
                     RNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPYENTGELKSDED
                     LEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGISRDYLYFTTLA
                     EAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITTTIDQKIHSAMQ
                     SAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNHAFDTKRSPAST
                     TKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMTLGEALNYSWNI
                     PAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQHTNGYQTLANN
                     GVYYQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVLSSRVTTTFKSN
                     LTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNHSLSRRAGYSNN
                     SNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVSVEGKEVEVTGS
                     TVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSSSSSSSSDSSNS
                     STTRPSSRARR"
     gene            2481..3392
                     /locus_tag="VU722_001269"
     CDS             2481..3392
                     /locus_tag="VU722_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU1772245.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            3622..4320
                     /gene="dapD"
                     /locus_tag="VU722_001270"
     CDS             3622..4320
                     /gene="dapD"
                     /locus_tag="VU722_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU1772246.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            4388..5518
                     /locus_tag="VU722_001271"
     CDS             4388..5518
                     /locus_tag="VU722_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU1772247.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVDAVSSFLKKKAAE"
     gene            5530..6069
                     /locus_tag="VU722_001272"
     CDS             5530..6069
                     /locus_tag="VU722_001272"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU1772248.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            6053..6730
                     /locus_tag="VU722_001273"
     CDS             6053..6730
                     /locus_tag="VU722_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU1772249.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(6797..7696)
                     /gene="galU"
                     /locus_tag="VU722_001274"
     CDS             complement(6797..7696)
                     /gene="galU"
                     /locus_tag="VU722_001274"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU1772250.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(7718..8734)
                     /locus_tag="VU722_001275"
     CDS             complement(7718..8734)
                     /locus_tag="VU722_001275"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU1772251.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            8946..9385
                     /locus_tag="VU722_001276"
                     /pseudo
     CDS             8946..9385
                     /locus_tag="VU722_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(9500..9925)
                     /locus_tag="VU722_001277"
     CDS             complement(9500..9925)
                     /locus_tag="VU722_001277"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772252.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(9993..10643)
                     /gene="phoU"
                     /locus_tag="VU722_001278"
     CDS             complement(9993..10643)
                     /gene="phoU"
                     /locus_tag="VU722_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU1772253.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELACARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(10658..11410)
                     /gene="pstB"
                     /locus_tag="VU722_001279"
     CDS             complement(10658..11410)
                     /gene="pstB"
                     /locus_tag="VU722_001279"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1772254.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(11412..12227)
                     /gene="pstA"
                     /locus_tag="VU722_001280"
     CDS             complement(11412..12227)
                     /gene="pstA"
                     /locus_tag="VU722_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU1772255.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLVIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(12220..13083)
                     /gene="pstC"
                     /locus_tag="VU722_001281"
     CDS             complement(12220..13083)
                     /gene="pstC"
                     /locus_tag="VU722_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU1772256.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(13201..14076)
                     /locus_tag="VU722_001282"
     CDS             complement(13201..14076)
                     /locus_tag="VU722_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEU1772257.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(14243..15574)
                     /locus_tag="VU722_001283"
     CDS             complement(14243..15574)
                     /locus_tag="VU722_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU1772258.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(15575..16282)
                     /locus_tag="VU722_001284"
     CDS             complement(15575..16282)
                     /locus_tag="VU722_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772259.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(16366..16668)
                     /locus_tag="VU722_001285"
     CDS             complement(16366..16668)
                     /locus_tag="VU722_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU1772260.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(16655..16876)
                     /locus_tag="VU722_001286"
     CDS             complement(16655..16876)
                     /locus_tag="VU722_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU1772261.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            16838..17396
                     /locus_tag="VU722_001287"
                     /pseudo
     CDS             16838..17396
                     /locus_tag="VU722_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17786..19477)
                     /locus_tag="VU722_001288"
     CDS             complement(17786..19477)
                     /locus_tag="VU722_001288"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU1772262.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILNLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIATELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKAQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            19613..20059
                     /gene="argR"
                     /locus_tag="VU722_001289"
     CDS             19613..20059
                     /gene="argR"
                     /locus_tag="VU722_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1772263.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLANETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            20110..22644
                     /gene="mutS"
                     /locus_tag="VU722_001290"
     CDS             20110..22644
                     /gene="mutS"
                     /locus_tag="VU722_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU1772264.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIREILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQSLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAETAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIESGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            22791..24485
                     /gene="patA"
                     /locus_tag="VU722_001291"
     CDS             22791..24485
                     /gene="patA"
                     /locus_tag="VU722_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU1772265.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNFYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQTIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAVKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(24814..25077)
                     /locus_tag="VU722_001292"
                     /pseudo
     CDS             complement(24814..25077)
                     /locus_tag="VU722_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            25274..27040
                     /gene="patB"
                     /locus_tag="VU722_001293"
     CDS             25274..27040
                     /gene="patB"
                     /locus_tag="VU722_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU1772266.1"
                     /translation="MKTVQFFWNYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNVVLYIGLILV
                     MFSRNVTLALITIASTPLAFFMLIFIVKMARKSTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLVNTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            27179..27868
                     /locus_tag="VU722_001294"
     CDS             27179..27868
                     /locus_tag="VU722_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU1772267.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPLGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            27872..28051
                     /locus_tag="VU722_001295"
                     /pseudo
     CDS             27872..28051
                     /locus_tag="VU722_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28038..29387
                     /locus_tag="VU722_001296"
     CDS             28038..29387
                     /locus_tag="VU722_001296"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU1772268.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLIVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANSWVTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKSLMEGANTARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            29511..30971
                     /locus_tag="VU722_001297"
     CDS             29511..30971
                     /locus_tag="VU722_001297"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU1772269.1"
                     /translation="MLKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGVTPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     TDLETIFQMAKPFLEEAGCLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            30985..31419
                     /locus_tag="VU722_001298"
     CDS             30985..31419
                     /locus_tag="VU722_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU1772270.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAIPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         9157 a         6153 c         6905 g         9242 t
ORIGIN      
        1 ccagcaaaaa caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa
       61 aaaatctaaa accttagata agtcagccat tttcccagct attttactga gtataaaagc
      121 cttatttaac ttactctttg tactcggttt tctaggagga atgttgggag ctgggattgc
      181 tttggggtac ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt
      241 gaatcaggtc aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat
      301 tgcttccata gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa
      361 tctgaagaag gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt
      421 acccaaggcg gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg
      481 gggttcaacc ttgacccagc aactaattaa acagcaggtg gttggggatg cgccgacctt
      541 ggctcgtaag gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgaataaaga
      601 tgagatttta acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa
      661 tattgcaggg gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac
      721 tgttcctcaa gcagcatttt tagcaggact tccacagagt cccattactt actctcctta
      781 tgaaaatact ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa
      841 ggcagttctt tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta
      901 caaggattat gaccttaaac aggacttttt accatcgggc acggttacag gaatttcacg
      961 agactattta tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc
     1021 tcagagagac aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg
     1081 agatttggca gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca
     1141 gaaaattcat tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg
     1201 aacaggtcgt gtagaagtag ggaatgtctt gatggacaac caaacaggtg ctattctagg
     1261 ctttgtaggt ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg ataccaaacg
     1321 ttcgccagct tctactacca agcccttgct ggcctacggt attgctattg accagggctt
     1381 gatgggaagt gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat
     1441 tatgtatgct aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc
     1501 atggaatatc cctgcttact ggacctatcg tatgctccgt gaaaagggtg ttgatgtcaa
     1561 gggttatatg gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat
     1621 gggtggtggt attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa
     1681 taatggagtt tattatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt
     1741 ggtgtatgag tatcaggata aaccggttca agtctattca aaagctactg cgacgattat
     1801 gcagggattg ctacgagaag ttctatcctc tcgtgtgaca acaaccttca agtctaacct
     1861 gacttcttta aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa
     1921 ccaagacgaa aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggctggat
     1981 tgggcatgat gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta
     2041 catggctcat ctagtaaatg cgattcagca agcttcccca agcatttggg ggaacgagcg
     2101 ctttgcttta gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc
     2161 agggaaggtt tctgttgaag gaaaagaagt agaggtcaca ggttcgactg ttaccagcta
     2221 ttgggctaat aagtcaggag cgccagcgac aagttatcgc tttgctattg gtggaagtga
     2281 tgcggattat cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc
     2341 cagcagttca agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc
     2401 aagggcgaga cgataattct ctaaatgaag tggccaatca atggattgcc acttttttcc
     2461 tttcgtgtta caataagggt atgaatcagt atcagaaaaa gattgttaac ggaaaaattt
     2521 attcgctcct atccggctta atatggggaa tctgtggaat tttaggagag tacttcttta
     2581 ctcattatca ggtgtcttcg ggctggatta cctctatgcg tttgacactg gcagggagtc
     2641 ttgtactcat ttggtctgca atacaattaa aatcgcaagt gctagatatt tggcgagaca
     2701 agaaaaatta cctgcccttt ttagcctatg ctattttggg gattttttca gttcagtatt
     2761 ttttctatct ctgtgtagaa tactcaaatg ctacgacagc aactatttta cagtttatta
     2821 gccctgtctt tatcctcttt tataatcgct tggtttatca aaaacgagcg tcaaaaagcg
     2881 ctgttttcta tgttttggtt gccatgctgg gtgtttgctt gatggcgaca aagggagatc
     2941 tctctcagtt atccatgacg ccgctagctc ttataacagg tttgctgagt gccatgggtg
     3001 ttatgtttaa tgttatcttg ccccaacctt ttgctaagcg ttatggtttt gttcctacgg
     3061 ttgggtgggg gatgattttg gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc
     3121 tttcctttac tcttgatatt tggagtatct tgatttgcct cattatcgct ttctttggaa
     3181 cggcttttgc ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct ttggtggttt
     3241 ccgttatcag tgccagtgaa cctctctctt ctgctctctt gagtgttttg ttcttaggat
     3301 tagtagtgga ttggtccctc cttctagcta tagccttgat tattttaccc atgatatttt
     3361 tgtctataga agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg
     3421 ctatactaga atagtcaata aaacacgggg agatagttgt gaagagtgtt tttaggttgt
     3481 atcggtaggg gcttgctttt accgacagca cgttttatct cacaacccta aaaaatcata
     3541 cctaaaaaca gacaaaaagg tttcaaattt gaggcctttt ttggtagaat aggtatcatt
     3601 ataacgaacc aggaggcacc tatgactgct acaaaaatga acgctcaaga aattatccaa
     3661 tttatcgcca atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca
     3721 actgctgtgc ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac
     3781 gtggctccgc ttcttgaagg tttggtagaa aatcaagatt atgttgtcga gcaagatgct
     3841 cgtaattctg cagttccttt gctagataag cgtgctatca acgctcgtat cgagccaggt
     3901 gctattatcc gtgaccaggt ggaaattggt gacaatgctg ttatcatgat gggagctgtt
     3961 atcaatatcg gtgctgaaat cggtgctgga accatgattg acatgggtgc catccttggt
     4021 ggccgtgcca tcgttggaaa aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg
     4081 attgagccag ctagtgctga accagtccgt gtcggagaca atgttcttat cggtgctaat
     4141 gcagtggtta tcgaaggagt ccaaatcggt agtggttcag ttgtcgcagc aggagctatt
     4201 gttacccaag atgtcccaga aaacgtggta gtagcaggtg ttccagctcg tattatcaaa
     4261 gaaattgatg cccaaactca acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa
     4321 ttgtaaaagt aaaaaagagg cggaaccctt tttccagcct ctttctgcta tatcggagga
     4381 cagatagatg ttagatttga ttcagactag acgagattta caccagatac cagagattgg
     4441 cttggaggag ttcaagactc aggcttattt gctggatgtg attgagaaat tgactacggg
     4501 caaggatttt gttcaaattc gtacttggcg gacagggatt ttggtctacc tgcagggaag
     4561 tcagccggag cgaaccattg gttggcggac agatattgat ggcctgccta tcgtcgaaca
     4621 aacaggtcta ccttttgctt ctcaacacca aggtcgcatg catgcctgtg gtcatgattt
     4681 tcatatgacc attgccttag gctgtcttga gcgcgccctt gaggagcaac ccaagaataa
     4741 tctgctcttt ctatttcagc ctgctgaaga aaatgaagct ggtggtatgc tcatgtatga
     4801 ggacggtgct tttggagatt ggttgccaaa ccaattctat ggtctccatg ttcgtccaga
     4861 tttgaaagtc ggccagattg cgactaatac tcatacactc tttgcaggaa cttgcgaggt
     4921 gaagatccgt ttcaaaggca aaggtggcca cgcagctttt cctcatgaag ccaatgacgc
     4981 cttggtggcg gctagttact ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa
     5041 cccaatcgag ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt
     5101 catcacagac acagcttttt tacatggaac tattcgtgcc ttgacacagg acatgagtct
     5161 cttggtgcaa aagagggtaa aaacagttgc agaaggggtt gcagctgcct ttgatatgga
     5221 agtcgaagtg gaactcaaac aaggtggata cctacctgtt gagaacaatc cagccttggc
     5281 gcgtgaactg atggacttct ttgacgaaaa agacggaatc gagttgattg atatcgaacc
     5341 tgctatgaca ggcgaggact ttggttatct cctttcaaag gttgatggcg tgatgttttg
     5401 gctaggtatc gatagtccct acgctcttca tcaccctcaa atgagtccta aggaagaagt
     5461 cttagctatt ggggttgatg cagtctctag tttcctgaaa aagaaggcag cagaatagag
     5521 ggcttgtata tgaaatcgga attacgcaag caagtcttgc atgaaatgaa ggctttatct
     5581 caagaacaaa aacaggctat agaccaagct ttaaccgagc gaattttaca acaccccttt
     5641 tatcaagaag ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt tcaaacgcgg
     5701 gaactgattg agcaggcgct gaaggacggc aagaaggttt taatacccaa aacttatccc
     5761 aaggggcgca tggactttgt agtctatgat ccgcagcagt tggtaaaaac tgcctttgcc
     5821 ttactggagc cacagggaga tttggaagtg gtggatgtat ctcagattga tttgattcat
     5881 gttcctggcc tggcttttac gacggatgga tatcggattg gatatggtgg aggttattat
     5941 gaccgctatc tggaacattt ttctggtcat actttgagta cggttcatcc ttgtcaaatt
     6001 caggacttta tacctgaaaa ccatgatatt cctgttcagg aggtattaat tgatgaagga
     6061 aatctttgat agacgttacc ctgtgacgag tttcttcctc ttagtgacgg ccttggtatt
     6121 tttactaatg ttggtcactg caggcggaaa ctttgacagg gcagatacat tatttcgatt
     6181 tggagccatg tatgggccag ctattcgcct ctttcccgag caggtttggc gtctcttgtc
     6241 tgccattttt gttcatattg ggtgggaaca tttcattgtt aatatgcttt cactttatta
     6301 tcttggaagg caggtagagg agattttcgg ctctaagcag ttcttttttc tctatctctt
     6361 atcaggaatg atgggcaatc tctttgtttt tgtatttagt cctaaatcct tagcagcagg
     6421 cgcctctacc tctctttatg ggctatttgc cgcgattatc attcttcgct atgcaactcg
     6481 caatccttat atccaacagc tagggcaatc ctatctgaca ctttttgtgg ttaacattat
     6541 tggaagtgtt ctgattccag gaatcagcct agcaggccat atcggtggtg cagttggtgg
     6601 cgcatttcta gcagttatct ttccagttag aggagaaaaa cggatgtata acaccagcca
     6661 gagattagga gcggtagtct tgttcgtagg actcgccatt ttgcttttct acaagggaat
     6721 gggaatgtga cgaagttgaa agaaaatttg tgtaatgaaa aaagataagg cattttttga
     6781 accttatctt tttattttat tccttctcag tcaattcttt tccaagttgg atgaggtaat
     6841 tcttcaaatc atctttgact tgtggatgtt tgagggcgta gtcaatagat gttttcataa
     6901 agccaaactt atccccaacg tcgtaacgag ctcctgtaaa ttcacgggca aaaacacgct
     6961 gtgttttatt aagagtatcg attgcatcag taagttggat ttcatttcca gcaccaggag
     7021 cttggttttc gaggatttgg aaaatttcag gcgtgaggag gtagcgtccg ataatagcaa
     7081 ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa ggtttcaaca ctgtaaagac
     7141 catcttttcc ttcgccttgc ggagcaataa ccccgtaagc agatacttcg tcatgaggga
     7201 ctggcatgac agcgatagta gacgcgtggg tacgcttgta gtcatccatg agttgtttgg
     7261 taagtggaac agccttttcg tctgtgatat ccatcaagtc atcaccaagc ataacgacaa
     7321 aaggttcatt tccgacgaaa gccttggctt gcaaaacagc atctccgaga ccgcgtggat
     7381 gagtttggcg gataaaatgc agacgcatgc cagttgtttc atcaactagc ttcaaaagat
     7441 ctgttttccc tttttctttg aggttatatt ccaattcgaa gtttgaatcg aagtggtcct
     7501 caatagaacg ttttgattta ccagtgacaa ctagaatatc ttcaatacct gatttgagag
     7561 cctcttccac gataaactgg atagttggtt tgtctacgat tggcaacatt tctttggcaa
     7621 gggccttggt tgctggtaaa aatcgagttc ctagtccagc agcagggata actgcctttc
     7681 taacttttga tgtcataaaa atcctttcta tagagggtta agaccactca ttttctgctt
     7741 taaattcatt gttcatgatg tcataaatgg catctttgat attggttccg tgataaataa
     7801 cttggtaaat agcctgtgta atgggcatat agactccaag ttcttgggct agttcatagg
     7861 ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat attagcttct atatcagcta
     7921 gggattctcc tcgtccgaga gcatctccag ctctccagtt acgagagtgg atggaagttc
     7981 ccgttacgat caaatctccc acaccagata agccgctata ggtcaatgga ctggccccga
     8041 gtgctacccc taggcgggtg atttctgcta aacctcgagc gatgatggct gccttagcat
     8101 tatcaccaaa tccaagacca tgtaaagctc cagcaccgac agcaataata tttttaagag
     8161 caccagcagt ttcaaccccg ataacatccg tattggtata aagtcggaag tagtgattac
     8221 taaatagctt ctgaacgtat tgagctgttt gtaaatcttt agaagcagca gttattaaag
     8281 ttaggtcacg cacaatggtc tcttctgcat gactaggccc tgaaacaacg acgatatcac
     8341 tacggagatg ttcaggaatt tcttcttcaa gaatggttga taatcgttta tggctatcag
     8401 gttctaatcc ctttgatgcg tgcatgatga taaccttatg gtccaaggtt tgtgcaactt
     8461 gctgggcaac aagtcgtgtc acttttgttg ggacaacaaa caaaatcgca tccacatctt
     8521 tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc gtctagaacg acatctttaa
     8581 agtagtgctt attagtatgg tgtgtattaa tttcattgat ttgctcggga agatttcccc
     8641 aaatacgtac ctcgtgtcca ttgtcattta agacttgtga aagggcggtt ccccaagaac
     8701 caggccccaa gacggcgacg gtttgttttt ccatgatttc ctccttgata gagttctttc
     8761 tcttattcta tcatattcta gaggattttg cacttgcatt actggggtat ggtggaaaaa
     8821 tacacaaaaa ccgagacgaa gggataaact cttagtcttt agttaaagtg agaagaaatc
     8881 tgatagatag tttgattcag tatatgctta taatagaggt aaacaactca ggaggttctt
     8941 gtaggttgcg agagtttggc gaaaaaatta aaagattacg tttggctaaa aaaatcagtc
     9001 gttcagaatt ttgtggtgat gagtctgaat taagtatccg tcaattaatt agaattgaaa
     9061 atggagaatc cagaccaata ctaacaaagt taaaatatat tgctgaacgt ttgggggttg
     9121 aagattacaa gttgatgcca agttatatag agttggataa ggaataccta gaattgaagt
     9181 atttcttgat gaggattcct acatacgaag atgaaactat cgcccaaaag aaagagagtg
     9241 ttttgataag atttttgaag agtattatga taggttacct gaggaagaaa gatttatcat
     9301 cccaaattat tcatatctgg cactaacgaa ctacacagtt caaaaattac cagaaaagct
     9361 agttgaaata ctgtccttct ggtgattttg cttaatttct gatgttcgag acataattga
     9421 ggagatttgt cttgattttt tcctaaaaaa gggcagactc ctcccttggt ttgatgctcg
     9481 atttttaaaa taaggtgact tattctgtta ggcatgtttt cccctgccct ctagctctat
     9541 atggaacagg gagtatcaga tttatctggc agattgtatc aaataaggct tgaaactgtt
     9601 ttgaataggc gtatagactt gagaatttga gaatatgtcg tctagcagta gagacatatt
     9661 ttccggcaat atgaaggaag agacgtcgaa aacgcttgat agtcaaggcc tttacttcat
     9721 caccagctag ctgctttaaa aagaggtaga gattataagc cagacagccc atcatcatac
     9781 gtacttcatt cttaatcatg gtcgaactat ctgtcttatc cccaaagaat cctgctttcc
     9841 tttctttgat aaagttttca gcattccctc gttcacgata gaattgaaac agctcctcac
     9901 tatctacact gcttaaattg ttcaaatgaa cttttttaca accataaaaa agagcactta
     9961 atcgtactct tctcttttaa ggattagttg aattaattca aatccaccag ttctcctgtt
    10021 tctaggtaga ctaggcgttc acaaatgtta gcaatgtaat cagcgaagcg ttccagatgc
    10081 cctatgatat aaaggtattg agttccattg ggaattgagg tttcttggtc tttcataagt
    10141 ccaatgattt cctttgataa ggcataataa tattggtcaa tctgttcatc tttttgagca
    10201 atactaatag cttttgaggc ttggtgcaaa ggaaaggcaa ccaataaatc ggctagcatg
    10261 ctgagggata atttacccat ttggtgtaac tgttcttcgt caggggctag ttgattttct
    10321 tttagttgca aaacagcttt ggcaatgcct gccatatggt ctcccatacg ttcaaggtct
    10381 gaacaagaag acatgatgct aattacaaat cgaaggtcag acacttgtgg ctgctgcaag
    10441 gctaacaaac gggcacaggc caattcgata gcgctttgac cttggttgat agcatgatcc
    10501 ttattgataa ttagctctgc catctccttg tctttggagg ctaaggccag taaggctttt
    10561 gaagctgttt caaggacaag ttgccctagt cctaaaaagg attgttctaa ttcatgcaat
    10621 tctaagtcaa attgatttct cataggtttt tccttcctta tccgaaccgt cctgaaatat
    10681 agtcttctgt gcgctgatct tttggattgg taaacacgtc aacggtatct ccaaattcgc
    10741 aaatttctcc tgttaagaaa aaagcagttt tatctgaaat acgtgaagct tgttgcatgt
    10801 tatgggtaac aatgataatc gtataatcct tttttagttg ctgaatgagg tcttcaattt
    10861 ttaaagtgga gatagggtct aaggctgaag tcggctcatc cattaacaga atatcaggtt
    10921 ctactgctaa agctcgcgca atgcaaaggc gttgctgctg accgccagat aaggacatgg
    10981 cactcttttt aagatcatct ttgacttctt cccaaatggc tgcccctttt aaagatttct
    11041 ccactaaggc atctaattgt tttttgtctc gaataccatg tgtccttggg ccataagcca
    11101 cgttatcata gatagacatg gcaaagggat taggctgttg aaaaaccatc cctacacgct
    11161 tacgtagctg attaaggttg aatttgctac tataaatatc ttgctcatct aagaggactt
    11221 ggccttcaat atggcaagaa ggaaccaaat cgttcatccg attaagggtt tttagaaaag
    11281 ttgatttacc acaaccagat gggcctatca aggcagtaat ctgtctttct ggtaattgaa
    11341 tcgaaatatt ttttaaggct tgaaaatccc cgtaaaataa gtctaggtgt ctgactgaaa
    11401 atgttcccat actaggaagc tcctttcaca agtttccgag ataataagct tgatagagta
    11461 tttatcatta aaacagtaat aatcaaaatc acaccggtag cataggcttc attgacatgt
    11521 agcccctcac ttgacagcat atacatatgc agggctagag aacgacctga agacatgaga
    11581 ctacttggcg tattggtaga ggtacctaat gtatacatga gggcagctgt ttcaccaacg
    11641 atacggccaa tagctagtat cactccagct aaaatacctg gcatggcaac tggtagaaca
    11701 attctaaaaa cagtccgtaa cttacctgcc ccaagtccat aacttgcttg acgcatgcta
    11761 tcactaacag ataaaagggc ttcttctgtt gagcgaataa tgactggcaa caccatgata
    11821 actgaggtta agattcctga taacagagag tattgaaaac ctaagaagac tacaaagaag
    11881 agcatgccaa acagaccaaa aacaatggaa ggaatcccag ataaggtatc tgaggccaat
    11941 cgcatgattt taacacaaag ggaatctttt tttgtatatt ccacaagata aaaaccagca
    12001 aaaatcccta tgggcaaggc taaaagaaga gcaccaaaga ccagaataac ggtggaaata
    12061 atcgctggca taagggaaat gttctcagaa gtataagtcc aagaaaagag ggatagactt
    12121 agatgaggta agcctttgat gaggataaaa ccaatgacta aaaagagaga gccaaaggtt
    12181 aaagctgaaa aacaataaac gagaagtttt agcaggtatt tactcataag atgattttcc
    12241 tttcaagtag gcaaagtagg cattaatcaa gagaataagg aaaaagagaa ctgctgaggt
    12301 tgcaataagg gcttccctat gctgacctga tgcgtaagcc atttccagaa caatattggt
    12361 tgttaaggtt ctggttcctg aaaagagtcc acttggaata atcggttggt tgcctgctac
    12421 caaaataact gccatggttt cacctactgc gcgaccgatt cctaaaataa ctgctgataa
    12481 aataccagat ctcgcagctg gcaagatgac actaaaaata ctccgttcat gactagctcc
    12541 tagagccaag ctaccagaat aatacgtttt gggaactgtt cggatagcag attctgacaa
    12601 actgataatg gttggcaaaa tcattattcc taatagtaac gaagcggtta ggacactcat
    12661 gccatttcct aaaaagcttc taatccaagg caccaataat tgtaggccga aaaaaccata
    12721 aacaatagat ggaatggccg ccatcaagtt gatagctgat tttaagaagc catagacggg
    12781 ctttggacaa taataaacca taaacaccga tgtcaagatg cctgttggca ccccaatcac
    12841 aatcgctcct aaggtaatta ataaggaacc aacgatcatt ggtaaaatac catagcttgc
    12901 cggaatgttc gttggcgacc aatcactgcc taataaaaaa cgggcaaagc cgtagttagc
    12961 catgaaaggt aagccattac taaaaataaa gaaacagatt agcaaaatag ctacaacagc
    13021 tactgttgca ctcatgaaaa aaattgccct aaaaactgct tctttgaagg cttgttttat
    13081 cacatcttgt cctttctagt gaagaaagta agggagatac gacacctccc tacttgcctt
    13141 ctttatctta ttgtacgatg aaacgtctgc atctctttag agatttatgg agcaaacatt
    13201 ttatttaatc ttgtcccagg tggttaattt gccactaaaa acgtctgcaa gttcagccat
    13261 actgacttgg cttgccttat tgtcattatt gaccacaaca gcaataccgt ctaaagcaat
    13321 agcatcatgg gtgagactct taccttcttc aggagttaat tccctagaaa ccataccaat
    13381 atcagcggtt ttctccttaa cagcggtaat acctgctgaa gacccattag aggtaatatc
    13441 aatcgtaact tctggatttt cttttttata agcttctgct aatttttcca ttaaagaaga
    13501 tactgaagtg gaacctacaa cagacaactt gcctgataag tgttggctgg tatattctgt
    13561 ggtttcggtt ttagcttcaa taaatttatt atctgtgacc acttgttgac cttgtttgga
    13621 gtggataaag ctgataaaat cttgacctag cttggaaaga ttagaagacc aaacaatgtt
    13681 gaagggacgt tgaagagggt atttaccatc taaaactgtg tctcgactag ccttgacacc
    13741 atcaatctct aaagccttga cagatttcgt taaagatccc aaggagatgt agccgatagc
    13801 attagcattc ccttgaactg ctgagagaac accttctgta ctattttgaa tcacagctgt
    13861 tttggcagtg ttgtcaattt ttttatcacc gtcttttttg agaatccctg tgatttctgt
    13921 gaaggcaccc cgtgtcccag agccattttc tcgtgaaatc acctcaatcg ttcctgaagc
    13981 tgactgtttg gaagcagctg actgattgcc acaggcaaca agcccaaatc ctgataagcc
    14041 aatggctgca agagtaagca tttttttgaa tttcataata atcaccttta tctctatgta
    14101 tttttcttgt gtaggcttac tacatttata gtctaacaag tctttgtaaa ggtttatccc
    14161 tgattcatgt aaagattgtg taaagaatca aaaaaagcca cttttgaaaa atggctgctc
    14221 ctaaaaatag ctttaaaaat tattagtcct gtgcgaaaga ttggttagga agaaaaatcg
    14281 tgaagcaact gcctctgcca agctgactcg tcaccgtgac ttggccacct aataattgac
    14341 tgagttcttt gacaatggca aggccaagac cagtgccacc agtttgtctg cttcgacctt
    14401 tattaactcg gtaaaaacgt tcaaaaatac gatcctgctc taattgacta ataccaatcc
    14461 ctgtatctga tacagaaatc ttaatgcctt cgttcacctt ttgggtcttg acctcaattt
    14521 ttcccccttg ttcagtgtaa cggatggcat tggataaaag attgagtaag atttgggaaa
    14581 gtaattgact atctgatacg agggtgacat catctggcac ctgcaccttt agctgtaaat
    14641 ccttcttctt gagctgaggt tgcaagcttt gagtcaaatc ctgtacaaat tctgccaaag
    14701 aaagggtcgt ccattgtata ggcatttgtt gagccttaga taaggtaaga agatgctcaa
    14761 caatatgctc aagacgcaag ctttctttgt aaataatgtc tagaaagtca tccttgagcg
    14821 cttcttcttc agctgacatc cccttaatgg tttcagcaaa gcccttaatc gaagtaactg
    14881 gtgtcctcaa ttcatgggag gcatttgaga caaaggctaa atttaacttt tcataagttc
    14941 taatcgttgt taaatcatat agcaagacga gcacagcttc cacagattgg gtggggctaa
    15001 aaacgggaac tgctgtcact tctaaaatca agtcaccctc atgaaaccca cttacttctt
    15061 gttttaacct tgttttttga tcaaaggctt ggtgaactaa atttcgaata tccatccgtt
    15121 tgaggtcatc aagtgaactt atgtcgccgt ccacatcggg aaaataatga ggcagagagc
    15181 gactggataa taacatctga ccttgagcgg aaactaaaaa cgtccccatg gttaggtgcg
    15241 acagaagaac ctccattgtt tcggctaggt ccttgtattg ctgatcctgt tgggagactt
    15301 tggtttttag ggcagacaca tactgagcca aagactttaa gtcttcttgc cctttttcta
    15361 aaaagtattc actactggtc aagagaggtt ggtgcaaggt ctcaaaagca acttcccatt
    15421 tccaaaggca aaagagccag tagccacctt gtcccaaaga aagggctaga agaaagagac
    15481 cgatgccttt actgatccaa gttaatgcca tccctgcaat cagaatgagg ctaacactta
    15541 gattgactag ccaaaattga aggtagcgtt tcatctataa ctccttgaac ttataaccat
    15601 aaccccgaat ggttcgaata aattgagggg ctttaggatt gtcttcaatt ttttccctca
    15661 acttaccaat atgaacgtcc accaaacgtg tttcctgccc aaagtcatac ccccagatac
    15721 gttccaaaag acgctctcta gtcagtgtca tgttgggatg tttcataaga tagagcaaga
    15781 gttcaaattc ttttggggtc aaactcagta acttattcgc cttgtagact tcatgacgct
    15841 cagggtatac tttcaaggtc ccaaatagcc aagaatcgtc agcgatatta tctgaatcat
    15901 ctccttcttg ttctccttta gttcgcctga ggacagcctt gacacgcgcc agcaattctc
    15961 tagggctaaa aggcttggtc aggtagtcat cagcccctaa ttccaaggcc aaaaccttat
    16021 caaattcatc acttttcgca gaaaccatca taattggagt tttgacgcct ttggctctca
    16081 gccgcttaca aacttccatg ccatctaatt gtggtaacat gatatcaagc aagataaaat
    16141 caaagggttc tgtttctgcc aaagctaagg ccttccgtcc atttgttacc aattgagtag
    16201 aaaagccttc cttacttaaa tggtagtcaa gcaatttcag aatgtgttct tcatcatcca
    16261 ctaataagac ttgttttgtc atctattatc tcctattggt aacattataa cacaattatc
    16321 agaaatccta acattgctaa atcagattaa atttgcttat caagactagt atctggtcaa
    16381 acgctcaatc atctccttgt gctctggata ggtcgccagt agatctaccc tttcaaataa
    16441 ttcaaaatcc tcaaattcaa aaccaggagc aacaagacaa gaaaccagag cataatcctt
    16501 atcaactgtt gatccccaaa tagtgccctt aggaacacag tagtgaagtt gttgcccttt
    16561 ggatatgtcc aggcctaaag tgactgcttc gtagtgacca tctgctgtaa tcatgtgaac
    16621 agtaagtggg gatcctgcat gaaaatacca gatttcatct gctgtcaatc ggtgaaaatg
    16681 tgaaggattc gtttcttctt aataagaaat aaatactggt ataaagcgcc cttcccttac
    16741 cagcaaggtt tatagtgtct gaagcttttt ttgtttgtct aaaatagcca ccttcaacat
    16801 ggggagctaa ctctagagtt cttatcaagt cttctttatc cgtcggagcc aatgggttga
    16861 agtaactctt gttcaaagtg gtgttacgat ttcaagaact cctctcagtt ctgaggacac
    16921 ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa ttagcgaatt
    16981 attctggtaa aaagaaattt cacgttatga aggctcaagc gattgtcaca agtcaaggga
    17041 gaattgtttc tttggatatc gctgtgaact attgtcatga tatgaagttg ttcaaaatga
    17101 gtcgcagaaa tatcggacaa gctggtaaaa tcttggctga cagtggttat caagggctca
    17161 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccactaacag
    17221 ttgaagataa agcctataac catgcgctat ccaaggagag aagcaaggtc gagaacatct
    17281 ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct
    17341 tcggattacg aatgaatttg attgctggtc ttatcaatca tgaactagga ttctagtttt
    17401 gcaggaagtc tattatttgg ttaggtgaat tagtgaagcg tttaggcaag tgtctctggt
    17461 tacgacgtaa agaagcataa atcgataata tttatgtttc tttactagtg aaacgcctag
    17521 ccaaattacc atagttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
    17581 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
    17641 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
    17701 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
    17761 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
    17821 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
    17881 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
    17941 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
    18001 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt
    18061 tgccagctgt ttctggtttg aaatcggctt tacgtaagat agattggata cgagcgtagg
    18121 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcttct aggtcgaagt
    18181 cgtatccatt tgtacggtcg gttttgaggt catagaattt aatggctcca accccaacag
    18241 catgtgctac ctgatcttta ttttccaatt caggattttt tgcttcaatt tgggctttgg
    18301 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
    18361 agagtttctt cccttctttt gtaaccagac caaaaggaac gtgagtaatg tcgtcactcc
    18421 agtcgtagcc catctcttgc aagacagctt tgagctgttt aaagtgggca gattgttctt
    18481 gaccaacgac atagatagat ttagcaaatt ggtattcgtt tttacggtaa agggctgcag
    18541 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gcgggatgtt
    18601 caattccata tttctcaagg ttcacaactt gggcaccttc tgattcaaga agtagtcctt
    18661 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
    18721 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
    18781 cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc
    18841 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
    18901 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
    18961 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
    19021 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
    19081 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
    19141 tttcttgttt accaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
    19201 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
    19261 caaccttttc aaaggcttgg ctgttcattt tttcagccag ttcagtcgca atcatttgag
    19321 gtgctttacg ttcgactttt gcaagagaaa aagcagggaa agcgatgtct cccatttctg
    19381 agtttttagg ggtttccagt aaatttaaaa tagcctcttg gtccaggcta tcaatgatgc
    19441 tagataattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
    19501 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cccgtttttt
    19561 tggtataata tagctataaa tatagttata aatatacata taagaggatt ttatgagaaa
    19621 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
    19681 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
    19741 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
    19801 agcaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
    19861 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
    19921 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
    19981 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
    20041 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
    20101 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
    20161 aagcaatatc cagatgcttt tttgctcttt cgtatgggtg atttttatga attattttat
    20221 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
    20281 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
    20341 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
    20401 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
    20461 agcagtaagc cggacagtca gaataatttt ttggttgcca tagaccgcga aggcaatcaa
    20521 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat
    20581 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
    20641 gacttgtctg aggaagaaga acaaatcctc agctgccaga tgaatctggt actctcttat
    20701 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
    20761 acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac
    20821 ctcaaacctg ttatccgata cgaaattaag gatttcttgc agatggatta tgcgaccaag
    20881 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
    20941 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
    21001 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
    21061 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
    21121 ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg atctcttgca gttggcgact
    21181 accttgtcta gtgtgccacg gattcgtgag attttagaag ggatggagca acctgctcta
    21241 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
    21301 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
    21361 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
    21421 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
    21481 gatggctact attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc
    21541 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
    21601 ggagatatgc ttgaggcgcg tgaggagtca gccaacctcg aatacgaaat atttatgcgc
    21661 attcgtgaag aggtcggcaa gtacatccag cgtttacaat ctctagccca aggaattgcg
    21721 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
    21781 gagtttggtg acgattcaca aattgatatc cagaaagggc gccatgctgt cgttgaaaag
    21841 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
    21901 caactgatta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
    21961 acggcggtta tggcccagct gggttcctat gttcctgctg aaaccgccca tttaccgatt
    22021 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc
    22081 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
    22141 attctatttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
    22201 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
    22261 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
    22321 ttggagcagg atgggcaggt caccttcctt cacaagattg aatcgggacc agctgataaa
    22381 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
    22441 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
    22501 actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta
    22561 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
    22621 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
    22681 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
    22741 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
    22801 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
    22861 ttgctagttc acttctgcaa ccgcgttatt tgcaggaagt cttagacgcc ctccttactg
    22921 ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc
    22981 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
    23041 accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat
    23101 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
    23161 tcatgatgac cttccaaatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
    23221 tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
    23281 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgctaag tttcaaaccc
    23341 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
    23401 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
    23461 gtcaaaactt ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
    23521 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
    23581 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagactatc tttaccattg
    23641 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
    23701 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
    23761 ttggaagcct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
    23821 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
    23881 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggacgggg
    23941 ccgttaaaat cggtggcaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
    24001 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
    24061 aggggaaggg aaatgctact ctatttgaaa tggagcgtgc agccaatatt gcccaggcta
    24121 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
    24181 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
    24241 gtattctgat ttttgacgat tcgacctcag ccttggatgc caagtcagag cgcttggtgc
    24301 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
    24361 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
    24421 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
    24481 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
    24541 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc cttgaaaaag tccatttttc
    24601 aaaggtaatc ctgtgttaat ttcagaaatt acatcacttt ttgttcgtca aatggcagct
    24661 cttttttagg atataaaaca gggttcggat aagttttttt gcaaggtgga tgatggttat
    24721 attgtaatgt tttccttatt ctaacttagt cttaagatag gccttaaaag taggcgaaaa
    24781 gcgagcgcat gctttggcaa cttgtatgag tacctaccgc agatgagggg aaccccgttt
    24841 gaccattctt cctgctaaat caatctgacc tgactgataa atagaagaat ccagtccagc
    24901 gaaagcttgt aattgagcag gattatcaaa ggcatgaata tttcgaatct cggctaaaat
    24961 gaccgcccct aaacgattcc caatcccagt aaccgtcgtg atgaccgagt tgaactcagc
    25021 catcaagtca ttgacacatt tttccgcttt gtcaatgatc ctcttgtaat gtttgatgtt
    25081 ttcattacac gagataaaac gtttatgcgt tatcaaactc attaccaatt gaaacaaaag
    25141 ctgtggttag agcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc
    25201 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
    25261 aaggaggagt aaaatgaaga cagttcaatt tttttggaat tattttaagg tctacaagtt
    25321 ctcatttgta gttgtcatct tgatgattgt tctggcgact tttgcccaag ccctctttcc
    25381 agtcttctct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
    25441 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gtctgctggt
    25501 tttggttcta tttatttcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga
    25561 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
    25621 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
    25681 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatgttgttt tatacattgg
    25741 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
    25801 cccattggct ttctttatgc tgattttcat cgtgaaaatg gcacgcaaat ccaccaacct
    25861 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
    25921 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
    25981 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgttat
    26041 gaatgggatg agcctggtta atacagccat cgtcatcttt gctggttcgg ctgtgctttt
    26101 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
    26161 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
    26221 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
    26281 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
    26341 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
    26401 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
    26461 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
    26521 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
    26581 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
    26641 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
    26701 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
    26761 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
    26821 agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac
    26881 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
    26941 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
    27001 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
    27061 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
    27121 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
    27181 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
    27241 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
    27301 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
    27361 gctcattttg acaggaggcc aaaatgttca tcctcagttc tatggagaga aaaagaccgt
    27421 cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
    27481 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
    27541 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttagggac
    27601 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
    27661 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
    27721 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
    27781 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
    27841 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
    27901 tttttcaaaa tttttagaat gtggcatttt tacgcaaacg tttgaattct gataaaaatt
    27961 ggagaaattc gacaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
    28021 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
    28081 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
    28141 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
    28201 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
    28261 atgttttgat tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
    28321 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagcg ccacaaatcc
    28381 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
    28441 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
    28501 ctttccgtgt ctttaaagaa ctcttggtta agaaatatgg tcaagaagaa gctaacaaac
    28561 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaaca
    28621 gttgggtaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
    28681 ttggtttgct tccgatcgca gcatcaggag ctgacatcaa atctcttatg gaaggtgcga
    28741 atacagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
    28801 cagccgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
    28861 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
    28921 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cattcacttg
    28981 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
    29041 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
    29101 aaggaaagga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
    29161 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
    29221 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
    29281 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
    29341 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
    29401 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
    29461 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgttaaaag
    29521 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
    29581 cagcattgtt taactacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
    29641 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    29701 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    29761 agcgtttgga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
    29821 aatcttacgt tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg
    29881 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    29941 tcgcagaacg tgaagcagca ggggtcaccc caactgttcg tttggctgtc aatgagtcag
    30001 gtatctacaa gtggcatgat atggtcaaag gcgatattga atttgaaggt ggcaatatcg
    30061 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgcca
    30121 tcgatgacca tgatatgcaa atctcccatg ttatccgtgg agacgaccat attgctaaca
    30181 caccaaaaca gctcatggtt tatgaagcac ttggttggga agctccagag tttggtcaca
    30241 tgaccttgat tatcaattct gagactggta agaagttatc taaacgtgat accaacaccc
    30301 ttcagtttat cgaagactac cgtaaaaaag gttatttacc agaagcagtc tttaacttta
    30361 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    30421 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    30481 tagactggat gagcaatgat tatatcaaga atacagacct tgaaaccatc tttcaaatgg
    30541 caaaaccatt cttagaggaa gcaggctgtt tgactgacaa ggctgaaaaa ttagttgagc
    30601 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    30661 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    30721 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
    30781 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
    30841 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    30901 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    30961 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    31021 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    31081 gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    31141 ttccatctct gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact
    31201 aaggttaaga aagtattagc ctttcgagat aaaccacctt atggcggaag ttcagccatt
    31261 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
    31321 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    31381 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    31441 tctttttact ataagtt
//
LOCUS       DAVFJR010000023        30899 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVFJR010000023 DAVFJR010000000
VERSION     DAVFJR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.024"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(118..387)
                     /locus_tag="VU722_001299"
     CDS             complement(118..387)
                     /locus_tag="VU722_001299"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772271.1"
                     /translation="MQCARISLYEFIGDIFYSKITSCCIVAKDLSKNTMKLDVIFFED
                     RNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(638..1498)
                     /locus_tag="VU722_001300"
     CDS             complement(638..1498)
                     /locus_tag="VU722_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772272.1"
                     /translation="MVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQEYCQGQPY
                     GLLKKMLKRIRLSREISLLRATIIVYFFTHRILPLSVFTFMFSYILLFVQSYLGSNTA
                     WIGNRRLIIEDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAIFENLLDSY
                     LLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYDNEALRDLS
                     KQYLNKNISELQDGSFESGIQDAVASKQIVVINEFIACLNSRCVPSQYDRFFYKDRPY
                     IFSRKSPIKG"
     gene            complement(1447..1692)
                     /locus_tag="VU722_001301"
                     /pseudo
     CDS             complement(1447..1692)
                     /locus_tag="VU722_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2573..2785)
                     /locus_tag="VU722_001302"
     CDS             complement(2573..2785)
                     /locus_tag="VU722_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772273.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(2793..3104)
                     /locus_tag="VU722_001303"
     CDS             complement(2793..3104)
                     /locus_tag="VU722_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772274.1"
                     /translation="MGGAIYIPRWTITGAITGAAYAALAAEGGGGLQLVLASYGLRSA
                     LVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGADWIFTNIIDGWDGRRDNQLRI
                     G"
     gene            complement(3088..3165)
                     /locus_tag="VU722_001304"
                     /pseudo
     CDS             complement(3088..3165)
                     /locus_tag="VU722_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(3498..3803)
                     /locus_tag="VU722_001305"
     CDS             complement(3498..3803)
                     /locus_tag="VU722_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPAR17_0115 family bacteriocin-like peptide"
                     /protein_id="HEU1772275.1"
                     /translation="MELVLPNNYVDLEQEEMMYLDGGEPMSISAIVALAITIGGASYS
                     TGYVLGERVYYSGYKNSDYQKNKWGIRGAMLVAFGAVGAIVMLGFENRYYALVTGRG"
     gene            complement(3949..5290)
                     /locus_tag="VU722_001306"
                     /pseudo
     CDS             complement(3949..5290)
                     /locus_tag="VU722_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
     gene            complement(5287..5754)
                     /locus_tag="VU722_001307"
     CDS             complement(5287..5754)
                     /locus_tag="VU722_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU1772276.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(5747..7966)
                     /locus_tag="VU722_001308"
     CDS             complement(5747..7966)
                     /locus_tag="VU722_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU1772277.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIEDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            8432..9295
                     /locus_tag="VU722_001309"
     CDS             8432..9295
                     /locus_tag="VU722_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772278.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPMEEIRDMLEIVIYLRQHGAGELSEHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFHIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYTQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSILSHLEK
                     EVEIYYQAKER"
     gene            complement(9347..9934)
                     /locus_tag="VU722_001310"
     CDS             complement(9347..9934)
                     /locus_tag="VU722_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU1772279.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            10176..10847
                     /gene="sdaAB"
                     /locus_tag="VU722_001311"
     CDS             10176..10847
                     /gene="sdaAB"
                     /locus_tag="VU722_001311"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU1772280.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPDIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNVHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            10856..11728
                     /gene="sdaAA"
                     /locus_tag="VU722_001312"
     CDS             10856..11728
                     /gene="sdaAA"
                     /locus_tag="VU722_001312"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU1772281.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            11750..12382
                     /locus_tag="VU722_001313"
     CDS             11750..12382
                     /locus_tag="VU722_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1772282.1"
                     /translation="MISITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLIYQPDYIAHKPLEVLAYFQ"
     gene            12432..12659
                     /locus_tag="VU722_001314"
     CDS             12432..12659
                     /locus_tag="VU722_001314"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772283.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIYGKATLTWFEEIFEEYKSLHNKTHNIRC"
     gene            12870..13106
                     /locus_tag="VU722_001315"
                     /pseudo
     CDS             12870..13106
                     /locus_tag="VU722_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13149..14999)
                     /locus_tag="VU722_001316"
     CDS             complement(13149..14999)
                     /locus_tag="VU722_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU1772284.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTIHIE"
     gene            complement(15041..16198)
                     /locus_tag="VU722_001317"
     CDS             complement(15041..16198)
                     /locus_tag="VU722_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1772285.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            16256..17422
                     /locus_tag="VU722_001318"
     CDS             16256..17422
                     /locus_tag="VU722_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU1772286.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVMLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQSSSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            17561..17887
                     /locus_tag="VU722_001319"
     CDS             17561..17887
                     /locus_tag="VU722_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU1772287.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            17874..18467
                     /locus_tag="VU722_001320"
     CDS             17874..18467
                     /locus_tag="VU722_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU1772288.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            18460..19371
                     /locus_tag="VU722_001321"
     CDS             18460..19371
                     /locus_tag="VU722_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU1772289.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTDLTDSQLESTEKHFHAEN
                     IQVHGKVELTAKKYLRIILDQKENQRINWDVSSNYGSIFQFTREEPESRGTELSNPYK
                     TKKADVKDQLIARSDDDIELISTPSRR"
     gene            19433..20497
                     /locus_tag="VU722_001322"
     CDS             19433..20497
                     /locus_tag="VU722_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772290.1"
                     /translation="MKQEWFESNDFVKTTSKNKPDEQAQDGADKAEETIADLDTPIEK
                     NTQVEEEVSQAEAELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLPKATEKVT
                     IAEESQEALPQQKSTTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSSSSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEEEWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(20696..21531)
                     /locus_tag="VU722_001323"
                     /pseudo
     CDS             complement(20696..21531)
                     /locus_tag="VU722_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(21806..22792)
                     /locus_tag="VU722_001324"
     CDS             complement(21806..22792)
                     /locus_tag="VU722_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU1772291.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(23064..24539)
                     /locus_tag="VU722_001325"
     CDS             complement(23064..24539)
                     /locus_tag="VU722_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU1772292.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(24797..25720)
                     /locus_tag="VU722_001326"
     CDS             complement(24797..25720)
                     /locus_tag="VU722_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1772293.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(25734..26663)
                     /locus_tag="VU722_001327"
     CDS             complement(25734..26663)
                     /locus_tag="VU722_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1772294.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            27195..27419
                     /locus_tag="VU722_001328"
                     /pseudo
     CDS             27195..27419
                     /locus_tag="VU722_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27523..27678)
                     /locus_tag="VU722_001329"
                     /pseudo
     CDS             complement(27523..27678)
                     /locus_tag="VU722_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(27865..28476)
                     /gene="rpsD"
                     /locus_tag="VU722_001330"
     CDS             complement(27865..28476)
                     /gene="rpsD"
                     /locus_tag="VU722_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU1772295.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(28671..29723)
                     /locus_tag="VU722_001331"
     CDS             complement(28671..29723)
                     /locus_tag="VU722_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU1772296.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(29720..30418)
                     /locus_tag="VU722_001332"
     CDS             complement(29720..30418)
                     /locus_tag="VU722_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772297.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(30585..>30899)
                     /locus_tag="VU722_001333"
     CDS             complement(30585..>30899)
                     /locus_tag="VU722_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1772298.1"
                     /translation="INVKETSDTANDQMKKSGMKPETPAPGTTNSMPADTMASSTNTM
                     AGENMAASANKMSDTMMSDDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKE
                     EN"
BASE COUNT         9547 a         6452 c         5293 g         9607 t
ORIGIN      
        1 ctttttaaac atagtatcat cttccttcat tcctataaaa acatttccga ttgagagagc
       61 ttgtttttta atttcgttaa acaacaaaaa acgcaagctc aagtctgcgg acaatcttta
      121 tagccatttc atttctttca catctgtttt acgaacttta gcatatttct tagcgcttgt
      181 aaaatgtaga gtaactggtt taaatactcc gcttttgtct cttcgtaaac ctaaaactgc
      241 ggatctttta tttctatcct caaaaaatat gacgtccaat ttcatagtat ttttagataa
      301 atccttagct acgatgcaac aacttgttat tttagaatag aaaatatcac cgataaactc
      361 atataaagat atccttgcac attgcatcac ctaatcctgc gctacttgcc cataatcctt
      421 taatgtttct actaaaattc ttccaatctc ccctatcaag atagcttatt tatcctagac
      481 aatgcctact gcaacagtat aaataaaagt catccgccat cttttctggc aatcatatgg
      541 gtagcctaat gatatttcta gttactcaaa aatatctagc tatactagag ttatttctaa
      601 tccctaggac gcttgttaat ccaaatataa caaattttca ccccttaata ggactctttc
      661 tggaaaaaat ataaggtcta tctttataaa aaaatctatc atattgggat ggcacgcatc
      721 tggaatttaa acaagctata aattcattta taactactat ttgtttagag gcaacagcat
      781 cttgtatacc gctctcgaaa gaaccatctt gtaattccga aatatttttg tttaaatatt
      841 gttttgacaa gtctcttaat gcttcattat cgtaaatgat tcccaaaaat ccaaccttat
      901 atagtaaata atttaaactt acaaagtaat tgaatcccat agtatatttt tctttataaa
      961 gcaaaggtaa aactttataa aaaatatcta agtcaacctc actctgattc tgaagcaagt
     1021 aggagtcaag caaattttca aaaatagcta acaatatgat tggtgtaagg tttttgtatt
     1081 cacatgtcaa gtattctgag tatcgtgcag atgatatttc ttttatataa ctttttgaaa
     1141 gcaagatttt ttcaaattca tcctctatta ttaatcttct atttccaatc caagcggtat
     1201 tgctacccaa ataagattgt acaaatagca atatataaga aaacatgaac gtaaatactg
     1261 aaagaggtag aattctatgc gtaaaaaaat agacgataat ggtagcccgg agtaaagata
     1321 tctctcgtga caatcgaatt cttttcagca tcttttttaa cagtccgtaa ggttgtcctt
     1381 ggcaatattc ttgaactaaa ttaatcggaa tgacatctct caccatttct ggaaagtaga
     1441 gtaagtttat aggttgaaat ctccagctcc catcataagt aaatggatat agaaccaaat
     1501 acttaaaaga tttttttctt ataaacttaa ttatcacaat atgaatgact gttccaatga
     1561 agtatattaa atataaaagt aaaaccacca tcaatatact tacaaaaatc cccttggaat
     1621 caatggaaaa taaaatattg caactagaag cgaataaagt cccgctaata aatatttctg
     1681 atcatctttc attcaaaaca ccatattatt tactaagaat gcatcaatac aatagagcaa
     1741 ctctgtaagt caatatttga taaagcaaag ctttaaaccc ttccccagac gttagctttt
     1801 attcaaccca ctacagttga caaggagccc aaattattga taaaaacttt agtcatcatc
     1861 gtctctataa aaatattttc tatacactct tgataatacc aaaattaatg ccaatatcat
     1921 accaagagct ataataatag aatttattag atttatttta gtatatccaa tcactagtcc
     1981 aataattgga ctagcagaca tgcttagata taataaaaat aacaaaaaat gaatttcacc
     2041 aattcctgca aaaaaatgtt tcatagctat agttttacgc ccataaatac ccatcaaatt
     2101 taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaag acttcagcaa
     2161 cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca ccaatatatc
     2221 ttgttatagc acttagttac ctagataaga tatcctttag cttgcttcca aaatttaagt
     2281 ctacacctat aatatgagtt catattagta ctgctaaatc ctatctatag taatgtcaaa
     2341 cacctaaatc aagtcatctc tccaattcat tcaagaaatg aagaaaggca aaaaatcttt
     2401 aaaataagaa aagtgcatat tatcaggtgt tcaaaaatct tgataatatg cgttatataa
     2461 tagaaaaatt tactcaattt cattttcaaa ttgagttttt tcccagcctc atttttaatt
     2521 tatatcttca atagaatcta atgaccgagc tactgtatta cacagattaa tattatttag
     2581 tctgtaattt ttttaaaaaa cttaatagta aatttgctcc actgattgct atcaatattt
     2641 caattggtaa aaaatagtaa ttccaaataa aatgagaaat cagcaatgat agaaaaataa
     2701 caatatcaat tttcctgttg ttgacatact ctgtaatttt atgatacagg aatgcaacaa
     2761 taactgaaat taaaacaatc aacataagat tattaaccta ttctcaattg attatcacgt
     2821 cgcccatccc agccatcaat aatattggta aaaatccaat cagctccagc accaattcca
     2881 gcagatgcaa tacttctaat aacagtattt gcaaaagcat ttccaatatg aattcctaat
     2941 actcctaaac ctttaacaat cccagctacc agtgcggagc gtaatccata agatgcaaga
     3001 actagttgaa ggcctccacc tccttctgct gctaatgctg catatgctgc gccagtaatg
     3061 gctcctgtaa ttgtccacct gggtatatat atagcccccc ccatcaaggt acatcatctc
     3121 ttcttcatca atcacaacat aattatttgg taatacaagt tccatttgtt ttctcctttt
     3181 tattaagcat gcttaggatg gtttcctaac aagtgatcgc aggctttgtt tagttaccta
     3241 aattagactt ccttccttta tcttatttta aatatttaaa accagttact gcttgaagct
     3301 taacagttta cttaattcaa ataacagcta atcactgatt ccctgatttt atcaaatata
     3361 ctaataacaa caattgtgat acgatcatca ttataagaac aacatttaac gaatcaaagt
     3421 ttttccgaga taataataaa gcaacagcaa gcagtattat tactaaagat tgaataacta
     3481 ctattactct taacatttta tcctctgcca gtaaccaaag catagtatct attttcaaaa
     3541 ccgagcataa ctattgcacc tactgctcca aatgcaacca gcattgctcc cctaataccc
     3601 cacttatttt tttgataatc agagttttta tatcctgaat agtagactct ttctcctaac
     3661 acatatcctg tgctatacga tgcgccacca attgtgatag ccaaggcaac aatggccgaa
     3721 attgacattg gttctccgcc atcaagatac atcatctctt cttgttcaag atcaacataa
     3781 ttatttggta atacgagttc catttatttt ctcctttttt attaagtatg gttaggatgg
     3841 tttcctaaca agtaatcgtc gactgtgttt ctatcactta gctacctaga taagatatcc
     3901 tttctctacc ttatttgttt ttataggtta cctaaggttt aaaaccaatt attgcttgaa
     3961 acttaacatt tctaaaatcc aatcaagata ggtttcttta tcatagacaa tccgcacttc
     4021 aactggcata tccttttgga ggacgactgt ctcacttcca tgttttagag ttaaggtttc
     4081 taattatatc atgactttat aaagactaat attgccttct ttcgtttctt gggaaattgt
     4141 tcctgaatca atctgtctga cttgtccctt tagtgttcca tatttttgac tatttacacc
     4201 agtaatagca acatcagctt ttgctccttt cgaaacacga gaaatatcac tcgcaagtac
     4261 aaaagcttct acatagtaac ctttttcttt ccctgaaact tctgctatcg tttgcccctg
     4321 ctgaatagac attccttgtt tcaaaggtaa cagataatgc agagtacctt catttggcgc
     4381 taatatacta tgagctttat cttgacctgt tgccactcca agattagcct caagctctgt
     4441 aatactttta ttgttgtttg aacgagcagt acctaactca ctaactaatt gagcataaat
     4501 attataagcc tgagaagttg gatcattata ggtacggttc atatccttaa tattgctttg
     4561 ttgactatca atctcgctat tcttagaagt aatatttgtt tttaatgctt cgatttttgt
     4621 tgttatttcc gatatcttag tttctaactt agctttgtta tcagctgatg tcgtatctga
     4681 tagagaaggt gagtctcctt gctgttgaag ttgaagcaat tcattttgta gagcttgcaa
     4741 gtcggcatct aactgatttc tttcagctgt tattttattc aacttcgcat attcatcctg
     4801 aatctttgaa tactgggtac cattattata attttccgag tttaactgag acagatagta
     4861 ttcaactttc ccataatatt cctattcttc accagaatta gataaatgat tgtatttctc
     4921 atttaatgat tgttcaaatt tttgaaagat agcttctttt gcacgtaact tctccaattg
     4981 tttatttaaa gagctcgctt gtaaaccttc ttgtccactt gataacgaaa taatgacatc
     5041 tcctatctcc ttctgactta tgtaaagtaa ctaccttccc tgaaccaatt gctgatagga
     5101 actctgtacc tgttataact gaatttccat tcgcttttac aatatagttt ttgggtatat
     5161 aagctgcgcc aaccaatgca ccgcttaaga taatagcagt tgaaataatg agaataaacg
     5221 caaaagctgg tggtctctta tcaaagaaaa tacgagaata acgtaattct gatttattat
     5281 ataatttcat aggcttacaa ttggtctaaa aatatctact accatttttt caggagaaga
     5341 attaacataa actgtataga caatcccatc cgtttgaata tcattttcat agacatatag
     5401 atccaattta gaatacgcat actgtagata ctctggactg tcttcaaaac gaacatataa
     5461 acaatatgga acagagatag aatcctgtac atcataaatg ttactgtact gttgagcatt
     5521 atgagcttga atataaaact caaaatcagt cgttattaat ccatcatcat gaatagtagt
     5581 accacaactt tttacaatta atggaccaaa aatttgtgct tttaacaact gcaaatgttg
     5641 atgaaattta ttaatttcct gatctacatc ttctactttt gtatcatgta actttttaca
     5701 gataactgac tttagtacca gttttttatt atcttttacc tctaacttag ccataagtaa
     5761 cctcctctgt atctaacaca gcctgtgact gaatttgttg attcacttga acgctctgca
     5821 aaccaaccat tctagcatac tttccatttt tcgccattag ttcttcatga gtaccatatt
     5881 ccataatagt cccattttct aaaaagcata tcttatcaca tcgaagaatt gtagacagcc
     5941 tgtgggctac tacaattgtt gtcttatcca ttattttatt aaagattaaa tcctgaataa
     6001 tctgttcact aaatgaatct aagttagagg ttgcctcatc aaatatatac aaatcagctt
     6061 tactcagtag tgctcttgca atagccaatc gttgtttctc tccacccgag aaattttgac
     6121 cgccttcttc tacaaaggag ccataacgat tttgaagacg ttgaatcgta tcatgaatac
     6181 caacaatacg acaaactctc accatatcct catatgtaac agaaggatta ccaattttta
     6241 gattatcaat aattgtccct gtaaagagtt ctatggtctg aggaatgtag gaaattttct
     6301 tacgtagttt accatagtca agatctgata agtcattttc tcctatacga attttcccct
     6361 cactcggatt tataaatctt aataacaaac gaactagcgt actttttcct gctccgcttt
     6421 ctccaacaaa agctattttt tctccttgtt taattcgcaa attaaagtcc tcgataacag
     6481 gagggcgtga accataggca aatgttacat ctttaaattc aatgtcatca cataaggtga
     6541 agtctctaat actataatcc aaggcaatgt cttcacgatc tacttccatc aattcttgaa
     6601 gccgactaac cgcaacctgt acctcttgaa aggttaactg caagccaact aaattctgaa
     6661 taggttctgt aaaatattga cttaatgtct gaaaaaccaa gaggtcccca atagtcattt
     6721 ttccatcaat gataaataag gcgcccactc ccataaataa taacccaccc atggttgagg
     6781 tcattgaaga tattgtagat tgaatattct gcaaaacacc ctctttataa ccaatttcta
     6841 aagtatgaac aaatttttct tcaattttgt ttaaacgttg ttcctcatca tgctgagact
     6901 taatggtatc aatgttacga atagattcaa ttaactgtga attaagaagt ccatttgctt
     6961 ccatttgttc atgattaatt tttttataag gctttttaaa acagtatata agaatgatgt
     7021 taacaataac cataaaaact aatatcagaa ataaagattg attaatagtc caaaggacaa
     7081 ccgcactaat aactgacaag gtgatatcca tgactaatga aatagagact gacgtaaaca
     7141 cattctttat cgtcatcgca tcttgaaatc ttgttaaaac atcaccaact ctacgacttc
     7201 caaaaaaact ataaggaaga tgaataatat ggtcataata tcccattaaa accggtatat
     7261 caatttttcg agatagaaac aaaagaacgt gctgacgaaa tgcagataga agagtctgta
     7321 agaacgatac tattccaaat actatcaaaa acatatacag actatttttt aaagcatatg
     7381 gaatcacctc gtccatgata acttttgaaa agagactcga taaaatacca atgatactta
     7441 aaacaaagga agctaatatg actgtactaa tcaatccttt ttgattaaaa attaaccttc
     7501 caaataaatc aagaagtcct tttcccttta gtttccctct ttcaaaatcc gaatttggaa
     7561 ccataaaaag agtaatacct tgataaattt ctcccagttc gtcacttgac atcttgcgta
     7621 tgccactagc agggtctgct acgtaaaatt tactattcct tttgatacta tgtaatacca
     7681 caaaatgatt ttgacctaaa tcattcttaa cttgaagaat cgcaggaaat gttaattttg
     7741 gagtcaaatc ttccagtgct actcgaacag cttttactgt aaaattcaac ttattcagac
     7801 ctgaaacaat accactgaca gtcgttccat acatgtctgt accaataatt tccctaatct
     7861 tcatgattga tagttccttt ttgtaagata aaagaactgt tgaaacaact gccgcagcac
     7921 aatctgactg gtcatgttgc atcgtacaag gatatttttt taacatagaa atactcaatt
     7981 ctttagaatt catctaactt ttctttgatg tcacccaaac ctcaatcact gcccagtagt
     8041 tcttgaatta gtttattttc aaccgtatca ttctttgttc ttgatatctt tccaagcatt
     8101 gtagtacagc agatttttgt ccaaggacta agcctccttt aacaactcaa gctcccttac
     8161 attatatcgg ccagccccat ggaaagatta tagccagact aatcaatgat ataatacata
     8221 ctagaataca aaatattttt ttattcatac tttttctcct atctttattt tctacctaca
     8281 tagtacctct tattaagctc atttcaaaat tacgttaact tttttcacaa atttattttt
     8341 actttctttt ttacttttta cactgctatg atacaatatt tttaacaaga ttttattatt
     8401 tgttaacttt tttcacagaa aggagaaaat catgcgttat gatttcggaa aggtctataa
     8461 agaaatacgt gagtcaaagg ggctgaccca agaagaggtc tgtgggggtg ttctctcaag
     8521 aaccagctta tcaaaaatcg aaagtggcaa gacaacccca aaatatgaaa atatggaatt
     8581 tcttctccgt caaatcaata tgagttttga agagtttgaa tatatctgtc aactttatca
     8641 accaagtcaa cgcacagaga ttatgcaaac ctatctcaat atgcgttcca ttatcgggac
     8701 cagcgatctt gtcaatttat ttcaaaaatg ccaagactac ctcaagaccc accacgatct
     8761 ccctatggaa gaaatcagag atatgcttga aattgttatt tatctccgtc aacacggagc
     8821 aggggaacta tcagaacacg cagaacaggt tgtcaaaaaa ctttggaaaa aaattgaaaa
     8881 acaagataca tggtatgaga gtgatctaaa aatcctcaat accattcttt tcagttttca
     8941 cattgaatac ctccatctca tcactggaaa aatattgcaa cgcctagaag tctataaaaa
     9001 ctatcaacat ttatatgact tgcgaatgac aattctatta aacctttcca cactctatct
     9061 atacactcaa gataaaaaca tgtgtaagca aatctgctac actttactag aggacgccaa
     9121 gaataagaaa agctacgata ggcttgctat ctgctatgtc cgtattggga tttgtacaga
     9181 taatgctaaa cttatccaaa aagggttctc ccttctggag ctaaccgagg aaacttctat
     9241 actgtctcat ctcgaaaaag aagtagagat ctattaccaa gcgaaggaaa gataaaaaag
     9301 ccgagggatt tcctcgactc tttacatatt atttgttcgt tagttcttaa taccagccat
     9361 tgttaagcca gaagttttta gcagcagtcc atgaaccgta acgtcctgca acgtaggcat
     9421 ctgctacacg ttcttggttt tcagctgagt agtcaccgtt caggtatgaa tctgttaatt
     9481 ggtaacgtcc gatataacgt ccatttgtag ctgtatagct accacctgat tctttttgag
     9541 cgatccattc tttggcttct gcttcagatc cgcttacagt tgaaacaact gtttcactta
     9601 ctactggagt ttctgctact ggagctgaaa cagtttcatc ttgagcggct ggtgccgcat
     9661 aagtagctgg cgctggtgtt gcaacaggcg ctacagggcc atcgataacc aactcttgac
     9721 caacataaat caaatgaatg ttatcaatgt ggttgttttc tgccaatttt tcaactgttg
     9781 tgttgtgagt ttcagcgatt tctgaaagtg tatcaccttc tttaacagtg taagttgatg
     9841 attcttgagc agatacaaat gatggagcaa atactgcaaa caaggcagct actcctgcaa
     9901 gagttgcttt aatcttttta gttattgatt tcatattcga aaattctcct tctttctata
     9961 gttctatcat accctttaaa tattaccgtt tcttgacact tttatgtaga aatattacaa
    10021 aattattttt tatttcccta gataaggtgt tttttgtcat aaaagatact atttttatgc
    10081 tatttgaggt attagaaagg ttttcatcca caattaaagt caagaccctc attctttgat
    10141 ataatagaga taagaatttt tataagggga aactgatgaa atcacttcgt tttcaatctg
    10201 tctttgatat catcggacca gttatgattg gcccatctag tagccatacc gctggtgctg
    10261 ttcgtattgg gaagattgtc tcttccattt ttgatgatac tccgacagaa gttgaattcc
    10321 aactttttaa ctcatttgcc aagacctatc gtggtcacgg aacagaccta gcccttgttg
    10381 caggtatttt aggcatggat acagatgatc ctgacattcc aaacagtctg gagattgccc
    10441 acaagcgtgg tatcaagatt gtctggacca ttcagaaaga cagcaatgcc cctcacccca
    10501 acaccactaa aattaccgtc aaaaatgtcc acaagaccat cagcgtgact ggtatttcta
    10561 tcggtggagg aaatattcag gtaaccgaac tcaatggttt tgccgtctct ctcaatatga
    10621 atacaccaac tatcatcatc gttcatcaag atattccagg catgattgcc ctcgtaacag
    10681 aggcgctttc ccgctatggt atcaatatcg cccagatgaa tgtcactcgt gaaaaagctg
    10741 gtgaaaaagc cattatgatt atcgaagttg acagtcgcaa ctgtgatgag gctatcgaag
    10801 aaattcgaaa aatccctcat ctccacaatg tcaatttctt taaataggag gaagcatgtt
    10861 ttattctatc aaagaattgg tcgagcaagc agatctggac tttcaaggaa atgtcgcaga
    10921 actcatgatt acaacagagt ttgaattgac cggtcgcgaa cgtgaagaag tcttccttct
    10981 catggaacgc aatctggaag tcatgaaagc ctctgtccaa cttggcctca atgaaaataa
    11041 atctcgtagt ggcctgacag gtggagatgc tgccaaattg gaccactaca tcaaaaacgg
    11101 aaaaactctg tcagattaca cgattctctc tgctgcccga aatgctatcg cagtcaatga
    11161 acacaatgct aaaatgggct tggtctgcgc tactcctacc gcaggaagtg ccggttgtct
    11221 cccttccgtt ctcactgctg ctattgaaaa attagacctc agccacgagc aacaattgga
    11281 tttcctcttt gctgctggtg cctttggact agtcatcgca aacaatgcct ccatctcagg
    11341 tgctgaaggt ggctgtcaag ctgaggttgg ttcggcctct gctatgagtg ctgctgcctt
    11401 gactctggct gcaggtggaa caccttatca ggccagtcaa gctattgcct ttgtcattaa
    11461 aaatatgcta ggcctcatct gtgaccctgt tgcaggtttg gtcgaagttc cctgtgtcaa
    11521 acgtaatgcc atgggagcta gctttgcttt catcgcagca gacatggcct tggcaggtat
    11581 cgaatctaaa atccctgtgg atgaagtgat cgatgccatg taccaagtag gagcaagcat
    11641 gccaactgcc tttcgtgaaa cagctgaagg tggactcgct accaccccta ctggtcgtcg
    11701 cctccaaaaa gaaattttcg gagaataagc ttatcaaata ggagaaacca tgatctctat
    11761 cacagcgatt tttttcgatt tggatggaac cctcgttgat agttctatcg ggattcacaa
    11821 tgcctttacc tataccttta aagagctggg ggtgcctagc cctgatgcca aaactattcg
    11881 tggttttatg ggaccacctc tcgaaagtag ttttgcgacc tgcctgtcca aagaccaaat
    11941 ttctgaagcc gtgcagatat atcgttctta ctataaggca aaaggtatct atgaagctca
    12001 actctttcct cagattatag acttgcttga ggagttatca agcagttatc cactctacat
    12061 caccacgaca aagaatacat ctactgctca agacatggca aaaaacttgg aaatccatca
    12121 tttctttgat ggtatttatg gttctagccc tgaagcaccc cataaggcag atgtcattca
    12181 ccaagccttg cagacacatc aactagcacc agaacaagcc atcatcatcg gagataccaa
    12241 gtttgatatg ctgggagctc gagaaacagg tattcagaaa ttggccgtca cttggggatt
    12301 tggagagcaa gcagacttgc taatctatca acctgattat atcgcccaca aacccttaga
    12361 agttttggcg tattttcaat agcatagact gggtaacaac tccatttcag aagaaaatga
    12421 agtaatactc aatgaaaatc aaagagcaaa ctaggaaact agctgcgggc tgctcaaaac
    12481 actgttttaa ggttgtggat agaactgacg aagtcagctc aaaacactgt tttgaggttg
    12541 tggatagaac tgacgaagtc agtaaccata tctacggcaa ggcgacgttg acgtggtttg
    12601 aagagatttt cgaagagtat aagtctctac ataacaaaac gcataatatc aggtgttgat
    12661 gaactgcacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt ttattatgaa
    12721 attaacttat gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga
    12781 gaagctttca aataaatttg ggataaacaa ttctaatatt aggtacatga ttaaattgat
    12841 tgatcgttac ggaatagagt tcgtcaaaaa agggaattca agcatctatg tcacgcaagg
    12901 gaaacagcca agacaacggt aggatggaat ctttctttgg cattttaaaa tccgaaatgt
    12961 tttatggcta tgagaaaaca tttaaatcac ttaatcaatt ggaacaagcc attatagact
    13021 atattgatga ttacaacaat aagagaatta aggtaaagct aaaaggactt agccctgtgc
    13081 aatacagaac taaatccttc ggataaatta attgtctaac tttttggggt cagtacattt
    13141 tttctttttt attcaatgtg gattgtttga ttagcaaagg cgataatagc ttgcttcaac
    13201 tcatctccac tgagagtgcg gaactctcca atcttttgat tgatggattc taaaggcatg
    13261 acattaacct taccaacgaa aatcttatcc ataacttgat tgtcaacgag ttcggttgat
    13321 accaagagtt cttcgtagag tttttcacct gggcggattc caacttcaac gattggaatt
    13381 tcactttcag tatggccact tagaagcacc atcttcttag ccaagtcata aatcttgact
    13441 ggtttgccca tatcaaggat aaagacttcc ccatctttgg cataagcacc agcatggata
    13501 accagacggc tagcttctgg aatggtcata aagtaacggg tcatgcggaa gtctgtcacc
    13561 gttacaggcc caccttcagc aatctgacgt tcaaagactg gaatgacact accacggcta
    13621 ccaagaacat tcccaaaacg aactgcacag taggttgatt ggctacgttg gttaaagcca
    13681 gtgacaatca actccgccac gcgcttggtt gctcccataa catttggtgg attaactgcc
    13741 ttatctgtcg aaatcataac catcttagac actttagctt catcaacagc cttagcaaca
    13801 ttgtaagttc cacggatatt gtttttgaag gcttcttttg gattgcgctc catcatagga
    13861 acatgcttgt gggctgccgc atgataaaca atagcaggtt tgtactgctc aaagacttgc
    13921 aacaaacgat catagtcttg aatgtccgca atcacaggta cataatcaat cccttggaac
    13981 ttacgaatca attcatgata aacaaggtag attgagtttt ccccatgacc gagcaagaca
    14041 atgcgttcag gattgaagcg actaacttga cgacagattt cagaaccgat tgaacctcca
    14101 gctcctgtga ctaagatggt cttacctgtc agttctgcac ccagacgcga ttcgtcaaga
    14161 cggatttcct gacgacccaa aaggtccgta atatcaattt tttggaagcc agtacctgct
    14221 tggtgaaggc cctgaacaac agtttcaacc ttaggcatct tgtaacattt gacacccagc
    14281 ttattacaca tctgcaagat acgctcatat tctgacggat ccagcgacgg aatcgcaacg
    14341 atgacacgct cgatttgatg gcgtttggct aattcaggca gattgtcata agagcccaaa
    14401 acaggaatac caccaagttt ttgacccttt ttcttagaat ccttatccaa aataccgacc
    14461 agttctaatt cactggttgg atgttggtaa ctatccataa agagagcccc accatcaccg
    14521 gcaccaatca agaaggtccg acggtgttct ccatcaccac tacctttttt gcgtctggag
    14581 tagattaact gccaagtaat ccgtggcaat aaaatcaaga aggtactcaa caagataaag
    14641 agaatgatga aacggatgga gaagagtggc aagaaggcat aacagatact atatgacaag
    14701 acactgctag cagtcacacc aaaaaagatt ttcatgaaat ccgtaatctt gctgtaacga
    14761 ctaatgctcg cgttcaaccc ccaaaaacca atcatcaatt gatagaacag gaaggccaaa
    14821 ctcgtataga taatgtagtc aacaggtgct ggattaatca gtccataaaa taaaatataa
    14881 gatacaatga tggaaaccac catactgaaa atatcaaata ttccccagaa aacctgcttt
    14941 tgttgtttat ttaaaatttc caccagatca atcacataat ctgttagttt tttattcata
    15001 gaaatctact cctccttaaa agagtttcac tatattgtta ttatagcata ttttgattta
    15061 tttggcttat tttatccaaa taaattattg ttcccttgta ctccttcttc catttaaatc
    15121 ctctaattaa acctacaatc gtcccaaagc cataagcaaa gtgaatggaa aataaaagaa
    15181 agggcatcac aattagaaat ccatttttat gttttaataa agtcagcaaa gtgagtagtg
    15241 acaaaagtag aaaataggca cctaatagta aagttatgaa tacgaatgtg atcggtaaca
    15301 atgctagact aaacacaaga ctcaaaacaa ataaacaagg aacatagtga aataatgata
    15361 aacacttaaa ctgaacatga cttgtcaagc caatccacaa accatttaaa tacttttgat
    15421 gcagcatttt cttgaatgtt ggtcgaatat actgataaga tagaatactt gggctatagc
    15481 ggattttata accatgttct cgaattctat aatgaatatc attatcttca gttcggccaa
    15541 gttgctcatt tactaaacca accttctgga aaacctctcg tttatacatc ccatgaaaaa
    15601 tagaagaaac atatctatcc tcggaactat ttcgataatt ggcaatgcta ctgccaaaca
    15661 tattttcctc aacaagatgc aaggtctctg cccattttcc ttttccttcg acaatcgtcg
    15721 gtctaggccc cccacagaca aattcacctt gttgaataat agccacattg ttcattacaa
    15781 aactctcagt aacttttgaa tgagcatcaa tttttaaaat aaggtcccct acagaatgtt
    15841 taactcccag gttaaaacca ctagcttgat ttttcttagg attgttatac aatctaattg
    15901 agttaaactc tgtatcttcc tttataaatt gctgaatgat agctgtggtc ccatctgtgg
    15961 acatagcatt tataaataga atttcaatat tctctttagg ataggtttga ttttttaagt
    16021 cttcaattag accaggcaga tatttttctt cattgtatgc actgattaca atggatacga
    16081 gaagactttc aacattttga gtcactacta ctctcctgaa tttttccttc caccattcta
    16141 tcataatttt caagactttc ccatttttat cttgaaagcc agaaacctta cttgacatta
    16201 tagtgaaaaa gccttaaaat aagctgttat taaaatcagc tagaagaggt attatatgaa
    16261 aaagcaatca ctcttttttg ttccaggtat tatcctgatt ggtgtttcct tgcgaactcc
    16321 ttttactgtt ttacccatta ttttgggaaa tatttcgcaa ggtctggagg tagaagttag
    16381 ttcgcttggt gtcttgacca gcctgcctct ccttatgttt accctctttt caccattttc
    16441 tacccaactg gctcagaaaa tcggcttgga gcatctcttc acctacagcc tcttcttctt
    16501 gaccatcggc tcacttattc gactaatcaa tctgcccctg ctctatctag gaaccttgat
    16561 ggttggggca agtgtcgcag tcatcaatgt catgcttcct agtcttatcc aagccaatca
    16621 accaaagaaa attggttttc tgaccacctt atatgtaacg tctatgggga ttgcaacggc
    16681 tctggcttcc tatctagctg tgcccattac acaatccagt tcttggaaag gacttatcct
    16741 cctcctcaca ttactctgtc tagcaacttt tttggtctgg ctcccaaatc accgctataa
    16801 tcatagacta gctccacaaa ccaaacaaaa aagtcaaata aaggtcatgc gtaataaaca
    16861 ggtttgggca attattatct tttcaggttt tcaatccttg atcttttaca ccgtcatgac
    16921 ctggttacct accatgtcta tccatgcagg tctatccagt cacgaagctg gcttgctgac
    16981 ttctatctta tctctgatta gcattccttt ttcaatgacc atcccaagcc tgacaaccag
    17041 tttatctact cgcaaccgtc agctcatgct cactctggtt tcactagctg gtgtggtcgg
    17101 catttccatg ctctttttcc caatcaataa tttcatttac tggcttgcca tccatctcct
    17161 catcggaacc gcaaccagcg ccctcttccc ttatctcatg gtcaactttt cactcaagac
    17221 aagcgcccct gaaaagacag cccaattgtc cggcctatct caaacaggag gctatatcct
    17281 agcagccttt gggccaaccc tctttggtta cagttttgac ctattccact cttgggtacc
    17341 agctgtagct gccctcttgc tcatcgatat cctgatgact gtagccctct ttacagtgga
    17401 cagagcggat aagatccttt aaacttctag ttttagctag aagtttttta tatataaaaa
    17461 ttttacacat ttctcttgac agggctttct tttagatgta caatgtatgt gtagaaaaat
    17521 tatatataaa aatcttacac attagaaaag gaggtttccc atgtactttc caacatcctc
    17581 tgccttgatt gaatttctca tcttggctgt actggagcag ggtgattctt atggttatga
    17641 gattagccaa accattaagc tgatcgctaa tatcaaagaa tccacactct atcccattct
    17701 caaaaaattg gaaggcaata gctttctgac aacctattct agagagttcc aaggtcgcat
    17761 gcgcaaatac tactccttga caaacggtgg tatagagcag ctcttgaccc taaaagatga
    17821 atggacactc tatacagaca ccatcaatgg catcatagaa gggagtatcc gccatgacaa
    17881 gaactgaata cctgactcag ctagaactct atctcaagaa actacctgaa gctgaccgta
    17941 tcgaagccat ggactatttc agagagctct ttgacgatgc tggagtcgaa ggagaagaag
    18001 aactcatcgc tagtttggga actcccaaag aagtggccca cgaagttcta tccaatcttc
    18061 tcgataaaaa aatcaatgaa gcacccgctc aaaaaaataa ccgacaaatt ttacatatcg
    18121 ccttgttagc cctccttgca gcacctatcg gcattcctct gggaatcgcc atcctcgtga
    18181 ccctgttcgc aatccttgta gccgctttga ctgtcattct ggctttcttt gcagtttcca
    18241 tactgggtat catcggcgga ttcctatttt tagttgaaag tttcactgtc ctcgcccaag
    18301 ccaaatcagc ctttatcttg atttttggtt ctggtttact ggctatcggt gcttcttcgc
    18361 tagttttact aggcatttcc tatgtagctc gcttcttcgg tctactcatt gttcgcctgg
    18421 tacaatttgt tcttaaaaaa agaaagagag gtaaccagca tgcgtaaatg gacaaaagga
    18481 tttctcatct ttggtgtggt gactaccgtt atcggcttta tcctgctttt tgtaggtatc
    18541 caatctgacg ggattaagag cctactttcc atgtccaaag aacctgtcta tgatagccgt
    18601 acggaaaagc taacctttgg caaggaagtc gaaaacctag aaattactct ccaccaacac
    18661 gcgctcacca tcacagactc tttcgatgat caaatccaca tttcttacca tccatctctt
    18721 tctgctcacc atgatcttat caccaatcag aacgatagaa ctctgagtct cactgataag
    18781 aaactgtctg aaactccgtt tctctcttct ggaattggtg ggattcttca tatcgcaagt
    18841 agctactcta gtcgttttga agaagttatt ctccagctac caaaagggag aactctaaaa
    18901 gggatcaaca tctcagccaa tcgcggacaa accaccatca taaatgctag ccttgaaaat
    18961 gcgaccctca atacaaacag ctatatcctc cgaattgaag gaagtcgtat caaaaacagt
    19021 aaactcacaa cccctaatat cgtcaatatc tttgatacag accttacaga tagtcagcta
    19081 gagtcaacag agaagcactt ccacgctgaa aatatccaag tccatggtaa ggttgaactg
    19141 actgccaaaa agtatctcag aatcatccta gaccagaaag agaaccaacg aattaattgg
    19201 gatgtctcaa gtaactatgg gtctatcttc caattcacaa gagaagagcc tgaatcaaga
    19261 ggtacggaat taagcaaccc ttacaaaact aaaaaagccg atgtcaagga tcaactcatt
    19321 gcgagatctg atgatgatat tgagctaata tctacaccaa gcagacgttg acaaaaacgc
    19381 ttacatctgc tactatggaa gcatatttat ctaacaaaaa ggaggttcta ccatgaaaca
    19441 agaatggttt gaaagtaatg attttgtaaa aacaacaagc aagaacaagc ctgatgaaca
    19501 agcccaagat ggtgcagaca aggctgaaga aacgatagcc gatctcgata cgccaattga
    19561 aaaaaatact caagtagagg aggaagtctc tcaagctgaa gccgaactag aaagccagca
    19621 agaagagaaa attgaaactc ctgaagacag tgaagcgaga acagaaatag aagaaaagaa
    19681 ggcatctaat tctactgaag aagagccaga ccttcctaaa gcaacagaaa aagtcactat
    19741 agctgaagag agccaagaag ctcttcctca gcaaaaatca actacgaaag agccacttct
    19801 tatcagtaaa tccttagaaa gtccctatat ccccgaccaa gctccaaaat ctagggataa
    19861 atggaaagag caagtacttg atttttggtc ttggctagtg gaagcgatca aatctcctac
    19921 aagcaagctt gaaacaagta tcacacacag ctacacagcc tttctcttac tcattctatt
    19981 ttcttcatct tcctttttct ttagtatata ccacatcaaa catgcttact atggacatat
    20041 agcaagcatt aacagtcgct tccctgagca gctagctcct ttaactcttt tttctatcat
    20101 ctctatccta gtagcgacaa cactcttctt cttttcattc ctcttgggta gtttcgttgt
    20161 gagacgattt atccaccagg aagaggaatg gacgctagac aaggttctcc aacaatatag
    20221 tcaactcttg gcaattccaa tcttcctcac tgctattgct agtttctttg ctttctttga
    20281 tagcctacga tttacagccc tcttgtgtgt gattagcatt ggaatcattc tacttgccag
    20341 tctccatatc attacaagac caagtcaagc aagtgaaacc gactccttct atcagttatt
    20401 cttatctgtc cttgtgaacg gagttattat cctcctcttc tttgtagctg aagtggcact
    20461 gattggagat tatcttcgta tcttggcctt tctttaaact tcatactctt cgaaaatctc
    20521 ttcaaaccac gtcagcttcg ccttaccgta ctcaagtaca gcctgcggct agcttcctag
    20581 tttgctcttt gattttcatt gagtagcaat cctgtcttcc atggcaggat tttttctatg
    20641 tcaaaaaagc aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa
    20701 atctttgtcc taggatgggt tgtatttcta tttgattggc gtctagttgg tggtaaaaag
    20761 atgggggtaa tacctctaag aattttgcat agtccaagcg ggctatggct tcatagtctt
    20821 ctggtttaga gccgtctcct gtgatttgaa ccaagtcaat ctcccactgc acttccttat
    20881 ccaccaattg ctcaatatag gctgcaggaa caaacggttc tctcggtaaa actgtcttga
    20941 ctccttgagc tagatggtaa acgccatgca cttttccttc tccatcctga tagaaggaaa
    21001 ctctcgcaaa gtaggcatct gtctcttgaa ccgcacacgc gcttcaaact gagccaagcc
    21061 atctgcctct aaaaaacttt tcaagttctc acgactaaag aaaataggat taaaaattcc
    21121 ttggcaaatc gtaaaacgag ctacagggtc tgctagatag gcttgaatac ttgcttggaa
    21181 ataagcttca aaatcaaaac catctagccc ttcaatatca gtccctgtat aagcaagcaa
    21241 agcatctaaa aatgacttga taatctgcca gtctgtcttt gttagtaggt caggaagatc
    21301 gacacggtaa gccttttgac catcagcata actgacctta aagagaaatt gtgattgccc
    21361 cactatcgca cactcgatat attcgagacg attaagaggc tgacggagat agactacatc
    21421 atagctatgt gactccaaac cgtctagcaa ggccaagatc gacttggcat tcaaaatctc
    21481 ttgctctcct aaaatgctct gtttatttgg aataaaaaat gttttcgcca taattggacc
    21541 cctttaaaat cgtttacata cagtatacct tatttttatg aaagatacaa aaacaaactt
    21601 tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgccgtag atatatgttc
    21661 ctgacttcgt cagtttcatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagc
    21721 ttcctagttt gctctttgat tttcattgag tattagattt ttgagtacaa agcatagaaa
    21781 aacagcccct gaggactgtt tgatcttata cagtagctgc ttgatccaag ctttcaccga
    21841 tagcggctag gcgctcgatc acttcagctt gtgtcaattc attttttgaa acatagcggt
    21901 tacgtgggtg aacacggcac tcgtgtgagc atccacgaag gtacttgtct tcattttctt
    21961 ctgatgtcaa gatacgacgg ttacagaagg gatttccaca gttgacataa cgttcacatg
    22021 gtgttccatc aaaccagtct ttccctacga tggttgggtt gacatggttg acatcaacgg
    22081 cgatacgctc gtcaaagacg tacattttcc catcccaaag ctcaccttga acttctgggt
    22141 ctttaccgta agttgcaatt cctccgtgca attggccaac atctttgtaa ccttcacgaa
    22201 ccatccagcc tgagaatttc tcacagcgaa caccacctgt acagtaaacc acgacacgct
    22261 tgtccatgaa tttttctttg ttgtcacgaa cccattgtgg caactcacgg aagttgcgaa
    22321 tatctgggcg aatagcccca cggaaatgtc ctaggtcgta ctcataatcg ttacgtgtgt
    22381 caaggacaac ggtatcttta tcaagaagcg cttctttgaa ctcttttgga gacaagtaag
    22441 cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc gttgtcttcc aaaccaaggt
    22501 ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa ggcttgttca ttttcttcgt
    22561 caatcttgaa ccagagttct tccattcctg gaaggctgtg aacgtagtcc atgtattttt
    22621 gagttgtttc atagtcacct gaaactgttc cgttaattcc ctcgtcagcg actaggatac
    22681 ggcctttaag accgattgat ttacagaaag ccaagtggtc tgcagcaaat tgctctgcat
    22741 tttcaattgg agtataaagg tagtaaagta agacacgaat atcttttgcc ataagatttg
    22801 ttctcttttc tattcttaaa ttttctaaat tttttattta tctacactag tatacctgct
    22861 tgagaaaacg aatgcaattt atttgactgg aaattgtaga gggttctcaa aatttcctga
    22921 atggttaaaa taaggacaag agaaaacatg gatatctata tccttgtgcc aaaaaaacca
    22981 ctgccctccc cagaccaacc tgaggaaagc agtgattctt attttaggag ttaggaatga
    23041 atacacgaaa tcaatttagc tgattatttt ttgtttttca agaattcatc gtattgtttt
    23101 tgcatttcat tcaatacttt ttcgtaggca ccttcagatt tcaacttttc catcaattct
    23161 ggaatcgctt tatctgggtc tacagtacca gtgttgatag ctgtatcaaa ttgttgcatt
    23221 gtgttagcaa tagctgagat ttcagatttc acattgtcag tattgaagat aaatccaagc
    23281 gctggagatt ctttagcttc tgccaattct ttcttagaat tttcgatttg ttggtctgta
    23341 acgttttcgt tgatgtaaag gatccagttg ttaccagtgt tccatccacc catgtgagtg
    23401 tttcctttgt agccatcaag aacgcgaaca cggttttctt taccttcaat tttttcccag
    23461 ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt ctggattcgt attcaagagg
    23521 ttcaagattt ccattgattt ttctttgttc ttagagttgt ttgagatgac aaagttagca
    23581 acttgtgttg tttggttttt cttgatgaag ttagtaattg gtttgatttg gatatctttg
    23641 ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg gtcctactgt ttcttcacga
    23701 acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc ttgttgcgac atcttttgga
    23761 atgtagccag cttcatagaa tttgtgaaga gtcttcaagt gttctttgaa acgaggcact
    23821 tcgtaacggt ttacaacttt agtagtatcg ccttcaagat caataacgaa tggaagcccg
    23881 tttgctactg ggtagtcaaa gttatcagat gggatgaaaa ctttaccaat agcaaatggt
    23941 actacgtctg gagctttttc tttaatttgt ttcaagactg gctcaagagt ttcgtaagaa
    24001 gtaacacctg aaatatcgat accatatttg gcaaggagag ttccgttgaa ggcaaagttt
    24061 tgagatgatg caacgttggc tgcaactgga acagcgtaaa ttttaccgtt tacagtatta
    24121 cccttgatgt aagctgggtc aagtgccttg taaaggtctt taccttcttt tttgtacaat
    24181 tctgtcaagt cagcataagc acctttttga gcatttacaa tatagttatc tgcaaaggcg
    24241 atatcatagt tttcaccaga tgatgtgata actgacattt tcttaccata gtcaccccag
    24301 ccaaggtatt ggatatccaa tttagcacca actttttctt cgatgatttt gttggcattt
    24361 gctaacaatt catccaagtt atctggtttg tcaccgattt ggtacatttt gataacaggt
    24421 ttgtcacctg aatcagcagc ttttttgctg ttacctgtca agttgccaca agcagcaaga
    24481 cctgcagcca gagcgactac actagcagat gcaaaagcat attttttcca gtttttcatg
    24541 ataaaaactc ctttttttat ttttaaactt ataaacaatg taatgatctt atactcaatg
    24601 aaaatcaaag agcaaactag aaaactagcc gcaggctgct caaagcactg ctttgaggtt
    24661 gtagataaga ctgacgaagt cagttacata tatctacggc aaggcgacgt tgacgcggtt
    24721 tgaatttgat tttcgaagag tattaacttc acacaaggga agttgggaac tgagaaatgt
    24781 tatttctcaa taagcactat tctttcacac caccgatagt caaacctttt acaaagtagc
    24841 gttggaagaa tggatacaaa atcgcgattg gaagggttgc taccacaacc atggccatac
    24901 gacctgtttc tttcggtaga gcaactccca gttgaccagt caagccgacc gctttggcaa
    24961 tgtagtccat attttgttgg atttgcatga gcaaatattg caatggatac aagttgtcac
    25021 tcttgatgta aagaagggcg ttgaaccagt cattccagaa accaagagct gtcaaaagcg
    25081 tgatggttgc gatacctggt agtgacaatg gcaaacagat ttggaagaaa atccgggcct
    25141 cactggcacc atcgatacga gccgattcga gaatggcttc tggaatggtc ttcttgaaga
    25201 aggaacgcat caagatgata ttgaatggtg agagaagcat tggaacaatc aaggcccaaa
    25261 cagtgtcacc aagctgaagt acacgggtca ccatgatata acctggtacc aaaccagcgt
    25321 tgaacaacat actgagaagg acgaagatgg taaaaaatct gcgatactta aaggttgtcc
    25381 gtgaaatagc gtaggcatag gttgttgtga taaagacatt tgtcaatgtc ccaactacgg
    25441 ttacaaagac agagatgaag agggcttgta ggattttatc cttaaactgt gccaaaaact
    25501 caaaaccgtc taagccaaat tgggatggga agaagctata gccgtattgg aggaggcttt
    25561 tctcgtctgt cactgaaata atgataacga atacaaaagg taggatacaa gagagggcaa
    25621 tcaaacccga aatgatactg aagaagatat ctgctttctt actgaaggag tgaatgccga
    25681 cattatcaat tttttctttt ttaattttct tttttgccat attctcctcc tttctagaac
    25741 aaagctgagt ttggatcgac tcgtcttgca agcaagtttg ataggataac cagaatcaaa
    25801 ccaacaacgg attggtaaag accggctgct gcagccatac cgatatctgc tgtctgagtc
    25861 aaaccattaa agacatatac gtccaaaacg ttggttacat tgtaaagctg accagcattg
    25921 tgtgggattt gatagaagag accgaagtct gcgcggaaga tatttccgac tgcaaggatg
    25981 gtcaatacag ttacaagcgg agtcaactga ggaatggtta cgttgcgaat acgttgccac
    26041 ttgctagctc cgtccactgt cgctgcttcg tagtaggttg gatcaattcc catgatcgtc
    26101 gcatagtaca tgacactgct atatccaaag cctttccaaa tacctaggaa aagtaggaga
    26161 tagggccaga tgcccaggtc agcgtaaaaa ttgacttctt tgagaccaag actttccaat
    26221 agatgattga acaccccttt atcaatattt aggaaggcat ctgtaaagaa actgatgata
    26281 acccaagaca agaagtaagg gaacaacata gaagtttgga aaatcttcac cattctctta
    26341 gaacggagct cgctgaggat aatggcaatc cctacagata caactaaacc tagaaagata
    26401 aagccaagat tgtagaggac agtatttcgt gtgataataa aggcgtctct tgaactaaat
    26461 aagaatctga aattatcgag tccgacccat ttactattta tgatactatc tatgaaacca
    26521 ttactggtca tgtggtagtc tttgaaggca accacgttcc caaatactgg aatgtaaaag
    26581 aatagaatca accagagtgc ccctggcaaa accatcaaga gaaagatcca gttgtctctc
    26641 aatgtttttg aaaacttttt cataatttcc tcccttttta ttttgatatc catctaaaaa
    26701 ttctttttta gacttttgat aacgattaca ttattagtat actcctattt gcaggttagg
    26761 ttaaactcct aattatagaa aaaactccac aaattatgta gcagatttaa aactttatca
    26821 ccactatcaa acaaatgtcc taaatcaatt gtttatttta tctctattag cccagtgatg
    26881 gcgtcactct gttataagca tccaacaacg gggtatactg aaaaatctcc agactaggga
    26941 actcagcgat agttcctaat ctggagattt ttaatatgtt attaggcgtt tgctttcaac
    27001 ttagcaataa cctctttaag attatcaatc aactctgctt cagtatgctc agagcctttt
    27061 tcatctgcca agaacaaaac tgctttttga agttcttctt gagagttttc aaggacatcc
    27121 ttatctactg tttcaaggtt tgagtctgct tactaatact agactaaaat caaaaagcat
    27181 tatataatag taatatgaaa tcaactaaag aagaaatcca aaccatcaaa acacttttaa
    27241 aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctatag taaaatgaaa
    27301 caagaacaag acaaatcgat ttctaacaat gttttagaag tagaggtgta ttattctagt
    27361 ttcaatccat tatatttcgt ctgatgggca aatcttataa agagattata gaacttttat
    27421 agtagtttga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaat
    27481 attttagcag ccaaggtgta ctgttataga ttcaatacac tatacttggt ggtttagctc
    27541 tcctgttttc tcttttggct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
    27601 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
    27661 atctattgaa tatgccataa aaagattata ccacattgtg tactattttt ggttcatttt
    27721 actatatcac tttggactat atcggtctag ttatgtctaa acgattatag ctggatacta
    27781 agagaaatca aaaaaagcac tctaggatag aggcctaaag tgcttagttt caaggcttta
    27841 cagcctatca tatttaataa aatattacaa cattttgttg tagaattcaa cgacaagtgc
    27901 ttcgttgatt tctgggttga tttcgtcgcg ttctggcaag cgagtcaatg aaccttccaa
    27961 tttttcagcg tcgaatgata cgaatgctgg acgtccaaga gtagcttcta ctgcttcaag
    28021 gattgctgga actttcaatg atttttcacg aactgagatc acttgacctg gagttacgcg
    28081 gtatgatggg atatcaacgc gtttcccgtc aacaaggatg tgaccgtggt ttacgaattg
    28141 acgagcttga cgacgagtag tcgcgagacc aagacggtaa acaacgttat ccaaacgacg
    28201 ttccaaaaga agcataaagt tgaaacctag gattccgcct ttgatttttg tagcttgtac
    28261 gaacaagtta cggaattgtt tttcacctac accgtaagtg aaacgaagtt tttgtttttc
    28321 agccaattgc aaaccgtatt ctgacaattt agaacggttg tttggtccgt gttgtcctgg
    28381 tacgtagtta cgacgtgcca attctttacc tgtacctgta agtgaaaggc caaggcgacg
    28441 agcttgtttc caagatggtc ctgtataacg tgacatatga atgtcctcct gatataaata
    28501 atatttcggt ggaaatagtc acttagaaag ccctgattcg tgcagatgcc cttcgcctaa
    28561 acagccaagg ttacttgtca taagacacct gttgacgagc ttcatgcttt cctgctgata
    28621 tttcacacaa aatctattct accatgaata gctggatttg taaaggggtt ttaggcttta
    28681 ttttcactac cagagaggtt gagaacgagg gtaaaggtac ttcctagacc gtactggctg
    28741 ctgactgtga tttccccacc caattgatgg gccaattcac gcgcaatcgc aagtcctaat
    28801 ccatgaccac ctgtcttcat gttacgcgaa gtttcgacac gataaaggcg tttgaaaata
    28861 ttttccaaat cctctggggc aataccctgc ccttcatcgg tcacactgat tgaaagctgg
    28921 tccttctcca gcttagccac cacttccagc ttggttcctg gagcagaata tttaaaagcg
    28981 ttatcgacca gattcaccaa gatacgagaa agcttagcat aatctccctc aatccgggca
    29041 gactctggga ttacctgcaa gtggacatct cttctctcct gctcaatcaa aaactgaaat
    29101 tcactcatgc actcaattaa gagcttgtcc agaaaaatac tgtctttact ggtagtttcc
    29161 acctgatttc tagctgtgtt tagggtcaaa aaattcaact cctcaaccag tttattgagc
    29221 ctctccgtct ggcgtccaat ggttgctaga taatgagctt gctccgactc cttgataatc
    29281 ccatccaaaa tcccttctac cgtcgcttgg atcgaagtga taggagtctt aatatcatgc
    29341 gacaactgag caatcatcaa gcccttttct cgttcgcttt cttccaagga atcaaagctt
    29401 acctgcaaat catgggacat ctcattaaaa gtttgcccta attgctgaaa ttctacagga
    29461 ccttgaacct ccaaatttga aggaaaatcc ttggccgcta cccgcttggc atgctccttg
    29521 agtttgccca acgacgtaaa gactggcaat aggagaaaga gactaatccc agcaccgaca
    29581 aggctggcaa cgatggtcat cccaagcaaa aagtaaatct cgcctttcgc aatcagcatt
    29641 ttttgaacag cccaaaaaac aaccaaaatg gttaagaggg ttgaaataat atatccaacc
    29701 aaaatataac tttttagttt catgtttgtc ctctcggttt ctctatctta tatcccaacc
    29761 cccaaactgt cttaatagtg ggcgtttggt cactactata ttttgccagt tcctgtcgaa
    29821 gagcatggat atgcacattc aaggtattgg tgtcatccac gtagtcttct ttccagatct
    29881 tttcatagag gtctgtcttg gagaaaactc gctctggatt gctagctaaa atccacagca
    29941 attcaaatga tttaacagtt aaatccagca tttcttctcc tatttgaact tcatgactac
    30001 tatgattcat ttttagattg ccaagggaaa tcagctctgt ttcgccccca cgatgaaggc
    30061 ggcgcaaaat attgtggaca cgcaaaacca gctcacgtgg gctaaaaggc ttagcaataa
    30121 aatcatctgc tcccaagctc aggccgtaaa tcttgtcctg ttcactggtc ttagcagtaa
    30181 taaataggaa aggctgctct ggtgataagt attgaacctc actgattaaa tcataaccat
    30241 ccatccgagg catcatgaca tctgtgataa tcaaatcaat cggttttttc ttgaacagct
    30301 ctagcgcttc cagtccatca tgggctacca agacctgata acctgcctga attaagtatc
    30361 tctgatgaat atctgtgatt tctacctcgt catcaacgag taaaattgtc tttcccatct
    30421 gtctctcctt tgataaaaac agtgctatac tgctttaagt ataacactat ttttattgtt
    30481 ttacgatgat tttaatctgc tattgaaaga aagtcctgat tgctgattga gttggtaaac
    30541 tagccttagt cagcccacta tccatcattt atttccttag ctgattagtt ttcttctttt
    30601 ttgtttttca aacctagacc accgagtaaa cctgcaagcg caagcccaag gaaaccaata
    30661 cttgccattg atgtttgagt ttcaccagta tttggtagca tagctttatc atctgacatc
    30721 atcgtatcag acatcttgtt agcagaagca gccatgtttt cacctgccat cgtgttggta
    30781 gaacttgcca tggtatcagc aggcatgcta tttgtagtac ctggagctgg agtttcaggc
    30841 ttcatacctg attttttcat ctgatcattt gctgtgtctg atgtttcttt aacatttat
//
LOCUS       DAVFJR010000024        30036 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVFJR010000024 DAVFJR010000000
VERSION     DAVFJR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.025"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            249..770
                     /gene="pyrR"
                     /locus_tag="VU722_001334"
     CDS             249..770
                     /gene="pyrR"
                     /locus_tag="VU722_001334"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU1772299.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVADREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            789..1712
                     /locus_tag="VU722_001335"
     CDS             789..1712
                     /locus_tag="VU722_001335"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU1772300.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPCEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIVNGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            1762..2841
                     /gene="carA"
                     /locus_tag="VU722_001336"
     CDS             1762..2841
                     /gene="carA"
                     /locus_tag="VU722_001336"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU1772301.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            3153..6329
                     /gene="carB"
                     /locus_tag="VU722_001337"
     CDS             3153..6329
                     /gene="carB"
                     /locus_tag="VU722_001337"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU1772302.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAIEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGGRRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLETGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGLENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(6604..7413)
                     /locus_tag="VU722_001338"
     CDS             complement(6604..7413)
                     /locus_tag="VU722_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1772303.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(7415..8218)
                     /locus_tag="VU722_001339"
     CDS             complement(7415..8218)
                     /locus_tag="VU722_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1772304.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSHENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(8228..9715)
                     /gene="tacF"
                     /locus_tag="VU722_001340"
     CDS             complement(8228..9715)
                     /gene="tacF"
                     /locus_tag="VU722_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU1772305.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRAFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVLPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            10051..10758
                     /locus_tag="VU722_001341"
     CDS             10051..10758
                     /locus_tag="VU722_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU1772306.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            10763..11785
                     /locus_tag="VU722_001342"
     CDS             10763..11785
                     /locus_tag="VU722_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU1772307.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            11802..12671
                     /gene="licA"
                     /locus_tag="VU722_001343"
     CDS             11802..12671
                     /gene="licA"
                     /locus_tag="VU722_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU1772308.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAIRLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            12661..13539
                     /locus_tag="VU722_001344"
     CDS             12661..13539
                     /locus_tag="VU722_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU1772309.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKIRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIVINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            13551..14240
                     /locus_tag="VU722_001345"
     CDS             13551..14240
                     /locus_tag="VU722_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP--phosphocholine cytidylyltransferase"
                     /protein_id="HEU1772310.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DASTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            14337..15185
                     /gene="dprA"
                     /locus_tag="VU722_001346"
     CDS             14337..15185
                     /gene="dprA"
                     /locus_tag="VU722_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU1772311.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIANIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            16069..17112
                     /locus_tag="VU722_001347"
     CDS             16069..17112
                     /locus_tag="VU722_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU1772312.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            17279..19366
                     /gene="topA"
                     /locus_tag="VU722_001348"
     CDS             17279..19366
                     /gene="topA"
                     /locus_tag="VU722_001348"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU1772313.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFDS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            19587..19946
                     /locus_tag="VU722_001349"
     CDS             19587..19946
                     /locus_tag="VU722_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU1772314.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            20039..20671
                     /locus_tag="VU722_001350"
     CDS             20039..20671
                     /locus_tag="VU722_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU1772315.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            20715..21371
                     /locus_tag="VU722_001351"
     CDS             20715..21371
                     /locus_tag="VU722_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU1772316.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMRISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTYKK
                     "
     gene            21390..22484
                     /locus_tag="VU722_001352"
     CDS             21390..22484
                     /locus_tag="VU722_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU1772317.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            22496..23533
                     /gene="leuB"
                     /locus_tag="VU722_001353"
     CDS             22496..23533
                     /gene="leuB"
                     /locus_tag="VU722_001353"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU1772318.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNCRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSILSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            23530..23799
                     /locus_tag="VU722_001354"
     CDS             23530..23799
                     /locus_tag="VU722_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU1772319.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            23803..24162
                     /gene="leuD"
                     /locus_tag="VU722_001355"
     CDS             23803..24162
                     /gene="leuD"
                     /locus_tag="VU722_001355"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU1772320.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNDLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            24324..24894
                     /locus_tag="VU722_001356"
                     /pseudo
     CDS             24324..24894
                     /locus_tag="VU722_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            24988..25053
                     /locus_tag="VU722_001357"
                     /pseudo
     CDS             24988..25053
                     /locus_tag="VU722_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            25216..27147
                     /locus_tag="VU722_001358"
     CDS             25216..27147
                     /locus_tag="VU722_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU1772321.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            27134..28450
                     /locus_tag="VU722_001359"
     CDS             27134..28450
                     /locus_tag="VU722_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU1772322.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPLTGNIAYTTREFTYDNPLMQLICHTIEYIKNQKSIGQGVLDSLLTS
                     RENVSEIMRVTPSYKLADRAKIIRGNKSKPIRHAYFHEYRKLQELCLMILNQEKHGLG
                     YQDQKIHGILFDVAWLWEEYVHTLLPKDFIHPRNKDKTDGISVFSSRERKVYPDFYNR
                     DLKIVLDAKYKKLEDTEKGINREDLFQLISYSYILKAEKAGLIFPSEKKAVDNEIGKL
                     AGYGALLKKWSIQIPQNSSSYREFCEMMERSEESFKRNITKELGRK"
     gene            28624..29610
                     /locus_tag="VU722_001360"
     CDS             28624..29610
                     /locus_tag="VU722_001360"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU1772323.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGSYFYIMHRFDEAGRIPFIKRMHEQGLIASISVGVKDYEY
                     DFVSQLKDDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            29674..29745
                     /locus_tag="VU722_001361"
     tRNA            29674..29745
                     /locus_tag="VU722_001361"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29707..29709,aa:Arg,seq:ccg)
BASE COUNT         9378 a         5290 c         6395 g         8973 t
ORIGIN      
        1 accagtaccc acaattatat gattttagca atttgtaaga tgctacattg aaactttttg
       61 cttgatttta agcatgcttt gtgctatagt aaatgataac taaatattcc tttaaacctg
      121 tcccgtgagg caggcaagga gcgcgataaa gtagaagggt gaagtctata ctgtgtgcag
      181 tagggctcgc ttggctataa atttcaagtc tccttgttta aggagacttt tctttttgga
      241 ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac cgtcaaacga gcgattacgc
      301 gtattactta tgagattatc gaacgcaaca aagatttgaa taagatcgtc ttggctggta
      361 ttaaaactcg tggtgtcttt attgcccacc gaatccaaga acgtttgaag cagttagaaa
      421 atctttcagt tcctgttgtg gaattggata ctaaaccttt ccgtgatgat gttaaaagtg
      481 gagaagatac ttctttggtt tctgtcgatg tggcagaccg cgaagttatc ttggtggatg
      541 atgtgctcta tacaggtcgt accatccgtg ctgctattga taatattgtc ggtcatggtc
      601 gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg acatagagaa ttgccaatcc
      661 gtccagatta cgttggaaaa aatatcccaa ccagtcgttc tgaagaaatc atcgtagaga
      721 tgacagaact tgatgaccaa gacagagttc tgattactga agaagcttag aaagttaaag
      781 gagtagccat gtcagaaaat caacaagcat tgaaccatgt ggtgtccatg gaagacctca
      841 ctgtcgatca agtgatgaaa ttgatcaagc gaggaattga gtttaaaaat ggagcccagc
      901 ttccctgtga agaccatccg attgtttcca atctcttctt tgaggattct acacggacac
      961 ataagtcctt tgaagtcgca gagattaaac ttggattgga acgacttgac tttgatgtga
     1021 agactagttc ggttaataag ggtgagacac tttatgacac cattttgact ctgtctgctt
     1081 taggagtgga tgtctgtgtg attcgccatc cagaggtcga ctactataga gaattgattg
     1141 ctagtccaac gattacgact tccatcgtca atggtggaga tggttcgggc caacacccta
     1201 gccagagctt gcttgatttg atgaccattt atgaggaatt tggccacttt gagggtctta
     1261 aagttgctat tgcaggtgac ttggatcact cacgcgttgc caaatccaat atgcagattt
     1321 tgaaacgctt gggagctgaa ctctttttcg ctggacctga ggaatggaga agtcaagagt
     1381 ttgcagacta tggacagttt gtaaccattg atgaaatcat tgatcaggtt gatgtcatga
     1441 tgtttctccg tgtgcaacac gaacgccatg atagtggagc tgtattttca aaagaagact
     1501 accatgccca acatggcttg actcaagaac gttacgatcg tttgaaagaa acagcaatcc
     1561 tcatgcaccc agctccaatc aatcgtgatg tagaaatagc agaccacttg gttgaagcac
     1621 caaaatcacg gattgtccaa caaatgacca atggtgtctt tgttcgaatg gcaatcttag
     1681 aatccgtact agcgagtaga aacgccaact aaaacacaag acgttaaaag acgccagtga
     1741 gcgtccacga gaggtgaaaa tatgacaaaa agaattctag tattagaaga tggcacagtt
     1801 tttgaaggca aggccttcgg agcagatatt gatgtaacag gcgaaatcgt ctttaataca
     1861 ggaatgaccg gctaccaaga atccattaca gaccagtctt ataatggaca aatcttgacc
     1921 tttacttatc ctttggtagg aaattatggt attaatcgtg atgattatga atccattatt
     1981 ccaacttgta agggagtcgt tgtttttgaa gaagcgcgta gagctagcaa ctggcgcaac
     2041 caaatgacct tggatgaatt tttgaaagcc aagaaaattc cagggatttc aggaattgat
     2101 acgcgtgctc ttaccaagat tatccgtaag catggtacta tgcgtgcaac cttgacccat
     2161 gttggggaca gtatggacca tgtgacggac cagctccaag caacagtttt accgacagac
     2221 aatatcaaac aggtttctac taaaacgtct tatccagctc caggagttgg tttgagcgtg
     2281 gtgctagtgg actttggtct caagcactca atcctacgtg aactttctaa acgcaactgt
     2341 aacgtgacag ttgttcctta ttcgacaacg gctgaagaaa ttctccatct caatcctgac
     2401 ggagttatgt tgtcaaatgg tccaggtaac ccagaagacg ttccacaagc actcgacatg
     2461 attcgcggtg tacaaggaaa aataccaatc tttggtattt gtatgggaca ccaactcttt
     2521 gcaatggcaa acggggctaa gacctataag atgaagtttg gccaccgtgg attcaaccat
     2581 gcggtacgtg aaatcgcaac aggacgagta gacttcacca gccagaacca tggttatgca
     2641 gtcagccgcg aggatttgcc agagcacttg attattacac acgaagaaat caatgacaag
     2701 tcagtggaag gtgtgcgcca cagataccaa cctgctttct ctgttcaata ccacccagat
     2761 gcagctcctg ggccacacga cgctagctac ctatttgacg agtttatcga gatgatggaa
     2821 gtttttaaac aatcaaacta agaacgagta aaagctcgtc ggagaattta tgtaactgaa
     2881 cacggacgga aagctcagaa tttagagaaa ccaacttgga ttgtcaatcc ttccttgatt
     2941 ttctaaaatt caatcgcttt ctattcgtcc tttgtatctt atttaatgtc gccctgagag
     3001 gcgacgaata gaaaggagaa gggtgctccg tatttgctga actgaatacg ggctacggac
     3061 ggtgctaaaa agatagttat tcctagaact gacagttcta ggaataactc ctattttagc
     3121 tttgtccgct tgacgccctt aatatcttat atatgcctaa acgtactgat attcaaaaaa
     3181 ttatggtgat tggttctggt ccgattatta ttggtcaggc tgctgagttt gactacgctg
     3241 ggactcaggc ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg gttaactcaa
     3301 atcctgcaac catcatgacg gacaaggaaa ttgctgacaa ggtttacatt gaaccgatta
     3361 cacttgagtt tgtgacacgt attcttcgta aggaacgtcc agatgccttg ctaccaacac
     3421 tcggtggtca gacaggtctc aacatggcca tagaattgtc taaaaatggt atcttagatg
     3481 agcttggcgt tgaacttctg ggtaccaaat tatctgccat tgaccaagcg gaggaccgtg
     3541 acctctttaa acaattgatg gaagagcttg aacaacccat tccagaatct gaaattgtta
     3601 acacagtaga agaagcagtt gcctttgcag cgacaattgg ctacccagtc atcgttcgtc
     3661 cagcctttac cctcggtggt actggtggtg gtatgtgtgc caatgagaaa gaattgcgtg
     3721 aaatcactga aaatggtttg aaattgtcac ctgttaccca atgtttgatt gagcgttcga
     3781 ttgccggttt caaggaaatt gaatacgaag tgatgcgtga ctcagctgac aatgccttgg
     3841 ttgtttgtaa catggaaaac tttgacccag ttgggattca cacaggggat tccattgtat
     3901 ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat gcgagcttga
     3961 gcattattcg tgccctcaag attgaaggtg gatgtaatgt tcagctagct cttgatccta
     4021 acagcttcaa gtattatgtt atcgaagtaa accctcgtgt atcacgttcg tcagcccttg
     4081 cttctaaagc gactggatat ccgattgcta agttggctgc caagattgca gtaggtttga
     4141 ccttggatga ggttataaac ccagttacag gttcaaccta tgccatgttt gaaccagccc
     4201 ttgactacgt agttgctaag attccacgtt tcccatttga caagtttgaa aagggtggac
     4261 gccgtctcgg tacacaaatg aaggcgactg gagaagtcat ggcaatcggt cgtaatatcg
     4321 aggaatctct tctcaaggcc tgccgctccc ttgaaactgg ggtgcaccac aatgaaatac
     4381 ctgaacttgc agcagtttct gatgatgcct tgattgaaaa ggttgtcaaa gcccaagatg
     4441 accgtctctt ctacgtatca gaagcaattc gtcgtggcta cacacctgaa gaaattgcag
     4501 agctaacaaa aattgatatc ttctatcttg ataaactctt gcatatcttt gaaattgagc
     4561 aagaattggg tgctcatcca caagatctag aagttttgaa aacagccaaa cttaatggtt
     4621 tctcagaccg taagattgct gaactctggg gaacgactga tgatcaagtt cgccaacttc
     4681 gcttggaaaa caagattgtt ccagtttata agatggtaga tacttgtgcg gcagagttcg
     4741 actctgaaac gccatatttc tattcaacct atggtttgga aaatgaatct atcaaatctg
     4801 ataaagaatc tgtacttgtc ctaggttcag gtccaatccg tatcggtcaa ggggttgagt
     4861 ttgactacgc aaccgttcac tctgttaagg ctatccaggc agctggttat gaagctatca
     4921 tcatgaactc aaacccagag accgtttcaa cagacttctc tgtatcagat aagctttact
     4981 ttgagccatt gacattcgaa gatgttatga acgtcattga cttggaacaa ccaaagggag
     5041 ttatcgttca gtttggtggt caaacagcca tcaaccttgc ggagccattg gcaaaagcag
     5101 gtgtgaccat ccttggtaca caggttgctg acctagaccg tgccgaagac cgtgacctct
     5161 tcgagcaagc tctcaaagaa ttggatattc cacagccacc aggacaaacg gctaccaatg
     5221 aagaagaagc agctcttgca gctcgtaaga ttggcttccc agttcttgtc cgcccatctt
     5281 atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga agaagacctt cgttcttaca
     5341 tgcgaactgc tgttaaggct agtccagatc atccagttct tgtcgactct tatatcgttg
     5401 ggcaagagtg cgaagttgat gccatttcag atggtaaaga tgtactcatt cctggtatca
     5461 tggagcatat cgaacgtgct ggtgtccact caggtgactc aatggctgtt tacccaccac
     5521 aaaccttgtc gcaaaaagtt caggagacca tcgcagacta caccaaacgc ttagcaatcg
     5581 gtcttcactg ccttggaatg atgaacatcc agtttgttat caaggatgaa aaagtctacg
     5641 ttattgaggt caatccacgt gccagccgta ccgttccatt tctatctaag gtaaccaata
     5701 ttcctatggc tcaagtagcg accaagctca ttcttggtca aagtttatca gaacttggct
     5761 accaaaatgg actttaccct gaaagcaccc gtgttcatat caaggcacct gtcttctcct
     5821 ttactaaact agctaaggta gacagcttgc tcggtcctga aatgaagtca acaggtgaag
     5881 ttatgggttc tgatgctact ttggaaaaag ctctctataa agcctttgaa gcttcttatc
     5941 tacacttgcc aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc aaagaagaag
     6001 ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg acagaaggga
     6061 cagcagcctt ctttgctagt catggcttgc aagcccaacc tgttggtaag attggtgatg
     6121 acgataagga tatcccaagt tttgtacgca aaggaagaat tcaagctatc attaacacag
     6181 taggaacaaa acgaactgct gacgaagatg gtgagcaaat tcgtcgttca gccattgaac
     6241 acggggtgcc cctcttcaca gcgctagata cagctaatgc catgcttaag gtacttgaaa
     6301 gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata agatatagca gactgaattt
     6361 agaacagtac acagggatac taaaatattt ctagaaatta atttgaattt tctaattgat
     6421 tcgttcgcat cttatttcaa tctactatag aaaaaagtct ttaaaattat aaaacgcatc
     6481 atatcaaggt ttttcaaaaa ccctgatatg atgcgtttta ttgtgggaat atgtatttca
     6541 ttttctacta aaattatgtt tttgaataac ctctatctta gtagtttgta taatccccct
     6601 caatcagttt ttgcgataag ctttaatgct atgactatac cactcttgca tttcttttga
     6661 tggtggtgtc atataatcgc catacatctg ggttaaaaat tggtcatatt ttttgggaac
     6721 aggcaacata cggccctcaa actcagttaa aatcagttct ttaaaggtat caactgggaa
     6781 gatttctttc atcccttcct taccgatccc aactcctcct tcatattgag gagtgttggt
     6841 tacagcattt ttgactagtt gatcaatttt cttgtaaaag tagcgaggat tgacaaatcg
     6901 gagagcgtac caactacata atctaagaaa atcttttagt ttgctatcac cgtgaactgc
     6961 tcgtgatttt ttgatataag ctagttgacg aagggccaca tacttatagc tcttgtcgac
     7021 aatgctcaag tctgtaaatc gatcaattgg gaagacatcg atgaaaaggc tggtatcatg
     7081 acgcttgtac ttaacatggt cttctataac agtagaagtg tccaaaatcg atgcgaaatt
     7141 atggaagtac caagaagatg tatcgtagga aagaaccttg tagcgagggt gattttcttc
     7201 ttcaataatc ttcagtaaac gctcataatc ctcacgataa agggaaatat caatatcatc
     7261 atcccaagga atcatacctt tgtggcggat ggctccaagc atggttccat aactgagaaa
     7321 ataaggaata tcatgtttct tacaagtctc atcaatatag tccagcaggg ctagttgaat
     7381 ttctttaatt tctttttttt ctaaatattg catcctaatc ctccaattta taagcgtgaa
     7441 attcatgact gtagaagcgt ttttcttctg gtggtagggt catataatct ccataaaatt
     7501 gtgtcaaaat agtatcaaat ttttcaggtg caggaaggct taaattctca aagggtaaat
     7561 cgattgtttt atcaaaggta ccacttggga agacttcctt ttccttaaat tttgaaggga
     7621 taaaagccat atactgccca ttttcatgac tatatttttg aatttctttc tcgattttat
     7681 ttgcaaaata acgaggagaa accggtcgaa ggagcaacca aaaggctgtt cgtatccaat
     7741 cttttaaaag gctatcctta tagacaatat ttttatgttt actgaaagac agcagtttga
     7801 agctttccag tttataacaa gtatcaatga ccttaggatc atcaaagcga tctataggga
     7861 aaatatcgat aaagatacca gactcatagg tttttgtatt tcgagtatca ataattttag
     7921 tcgtactgtc ggttatcttg ataaagttgt taaagtagtt cttatcagtt tctaaggata
     7981 ggagcttata cttgcttttt tccttttgaa aaatgttaat aaatcgttgg tagtcttctc
     8041 taggcatgga taaatcaata tcgtcgtccc aagggataaa gccctcatgt cgaaccgccc
     8101 caatcagagt accgtagtta ataatatagt tgatattgtg ctttttacag agagtatcaa
     8161 tataatccaa aatttctaat tcaatttgtt tggcatcttc aacggttagt tgtttcattt
     8221 taaactccta tgatttttta aatttatttt ttaaggctag gacatggttt aaaaattcat
     8281 agaaaatgct atcttttgtg aagacaagta gactaatata agagatagct gatagcaaga
     8341 caatcaaacc agtattaatt aaaaatggca aattaatgac catatccaca ggatacacga
     8401 aattaatcag gaaataaatt gctacaaagg aaagtgaaaa gagagagtat cgaacagtat
     8461 agctaaagat atgtcccaag tggatgagtt gttttctatg gatgaaaata atatagaaaa
     8521 caagtagaga agtctctgat aacatagttg tcagtaagta gtattcagga agcacgatat
     8581 ggttgaaaaa gaggagacta ttcaagccca aattgagtag cccagcaaag actgtataga
     8641 ctgtgatacg tttttcatag ccattggtaa agagaatttg ggaaccaaga atggtatcta
     8701 aggccaggat aatcgtacga aaagcgaaga gagaggtcaa gatgccgcct ccgatatatt
     8761 tttcactacc gtaaagtagg atggcatttg gtcctaaaac catgagtcca aaactcagtg
     8821 gaatgataaa gaagttaaag attcgactac ctctattaac cagagaaaca taggcttctt
     8881 tgtctccttt ccccagatag taactgagac gaggcacact cactccaatt gcacctgtta
     8941 caaccccagc tataacggtc acaattcgct gagctatggt atagtaacta acgttgacat
     9001 caatccctgt tttaacgagg aagaggcgat ctaaaaaagt gaagagcata ttggcattgg
     9061 caaagactaa catggctgtc agagggagaa agagtggttt aaaatcactt aggtgaatct
     9121 taacaagttt gatgtctctt ttaatccaaa aataactaat caggtagtta atcagcgtcg
     9181 ataaactcat cacaagtgta tagacaacaa tatcgtgttc atttttaaca aataagaaaa
     9241 tagagaccag catcaggata cggatgaagg cagttttgta aaagagaaaa ctgtaatttt
     9301 ccagagcttc attgacccat tcgattgaaa aaatctgggc aatgagttga atccccataa
     9361 caaggtagac ctttttgacg attggattat cagtaaagaa gagaggatag gctaggatat
     9421 agacagcagt ggtcaaaatc gtacaagcga tgcacaaata aaaaagacta gaaaaggctc
     9481 tgttaagatc ttttttgtta tccttgacat tactgatagc ccttaaaccg tagttataga
     9541 caccataagt tgcaaagggc aagaaaaatg acaaaatagt gtcgactgag ttgaagtaac
     9601 catagtcagt tcggtccaag acacgcgcga cataggttcc agttaggatg ggaaaaataa
     9661 tattcaagac acgaattccc atgtaagata gagcatttaa ttttatactt ttcattcaat
     9721 ttacctcgtt tttcattata tcataaagtt agctaataag aaatgaaggg cagtaagtca
     9781 agtaatcact ttgaagtttc aaatcttaaa ttttaagttt tctttaagga aagtatatta
     9841 ttctgaagga ctctaaaatt tcgcaaccat ttattagtaa ttgctacaga attcctagtc
     9901 attactagaa atggactagt ttctttgaat aatagaactg cataattctc ctattctaga
     9961 aggggaggac cagtatttct tttatgatag gactagattg tggtataata gagagaataa
    10021 gtttttttag taagacaaag gagaaaatag atgatttatg caggaattct tgctggtgga
    10081 actggcacac gcatgggaat cagtaacttg ccaaaacaat ttttagagct aggtgatcga
    10141 cctattttga ttcatacaat tgaaaaattt gtcttggagc caagtattga aaaaattgta
    10201 gttggtgttc atggagactg ggtttctcat gcagaagatc ttgtagataa atatcttcct
    10261 ctttataagg aacgtatcat cattacaaag ggtggtgctg accgcaatac aagtattaag
    10321 aaaattattg aagcgattga tgcttatcgt ccgcttactc cagaggatat cgttgttacc
    10381 cacgattctg ttcgtccatt tattacactt cgcatgattc aggacaatat ccaacttgcc
    10441 caaaatcatg acgcagtgga cacagtggta gaagcggttg atactatcgt tgaaagtacc
    10501 aatggtcaat ttattacaga tattccaaat cgtgctcacc tttatcaagg acaaacacct
    10561 caaacattcc gttgcaagga cttcatggac ctttatggat ctctttctga tgaagagaag
    10621 gaaatcttga cagatgcatg taaaatcttt gtgatcaaag gaaaagatgt ggccttggcc
    10681 aaaggcgaat actcaaatct gaagattaca accgtaacag atttgaagat tgcaaaaagt
    10741 atgattgaga aagactagta aaatgattaa tcaaatttat caactaacta agcctaagtt
    10801 tatcaatgtc aaatatcagg aagaggctat tgaccaagag aatcatatcc ttatccgtcc
    10861 caactacatg gctgtctgtc atgcggatca gcgttactat cagggaaaac gtgatcccaa
    10921 gattttgaat aaaaagcttc caatggcgat gattcacgag tcatgtggaa ccgtcatttc
    10981 tgacccgacc ggaacctacg aggttggtca aaaagttgtc atgattccca atcagtctcc
    11041 tatgcagagt gatgaagaat tctatgaaaa ctacatgaca gggacccatt tcttgtctag
    11101 tggatttgat ggctttatga gagagtttgt ttctctccct aaagatcgtg tggtggctta
    11161 tgatgctatt gaagatacgg ttgcagccat tacagagttt gtcagtgtgg gcatgcacgc
    11221 tatgaatcgt ctattgactc ttgctcatag caagcgggag cggatcgccg ttattggaga
    11281 tggaagttta gcttttgtgg ttgccaatat tatcaactat actttgccag aatcagagat
    11341 tgtggttatt ggtcgtcatt gggaaaagtt ggaactcttc tcatttgcca aagaatgcta
    11401 tattacggat aatattcctg aagatttggc ctttgaccat gcttttgaat gttgtggtgg
    11461 tgatggtact ggaccagcta ttaatgactt gattcgctac attcgtcctc agggaacgat
    11521 tctcatgatg ggagttagcg aatataaagt caatctcaat actcgcgatg ccttagaaaa
    11581 gggcttgatt ttggttgggt catctcgttc tggtcgcatt gattttgaaa atgctatcca
    11641 aatgatggaa gtcaagaaat ttgccaatcg tcttaaaaat atcctttatc tagaagaacc
    11701 tgtaagagaa attaaagata ttcatcgtgt ctttgcaacc gatttaaaca cagcctttaa
    11761 aacagtgttt aagtgggaag tataagtact ggaggttaat tgtggagaaa atcattaaag
    11821 aaaaaatttc ttccttactt agtcaagaag aggaagtcct cagtgttgaa caactgggtg
    11881 gaatgaccaa tcaaaactat ttggccaaaa caacaaataa gcaatacatt gttaaattct
    11941 ttggtaaagg gacagaaaag cttatcaatc gacaagatga aaagtacaat cttgaactac
    12001 taaaggattt aggcttagat gtaaaaaatt atctttttga tattgaagct ggtatcaaag
    12061 taaatgagta tatcgaatct gcgattaggc ttgattcaac gtcaatcaag accaagttcg
    12121 acaaaattgc tccaatatta caaactattc atacgtctgc taaggaatta agaggagaat
    12181 ttgctccttt tgaagaaatc aaaaaatacg aatccttgat tgaagaacaa attccttatg
    12241 ccaactatga atctgttaga aatgcagtct tctccttaga gaaaagactg gctgacttag
    12301 gtgttgacag aaaatcttgt catatcgatt tggtgcctga aaactttatc gaatcacctc
    12361 aaggacgact ttatttgatt gactgggaat attcatcaat gaatgatcca atgtgggatt
    12421 tggctgccct ctttttagag tctgaattca cttcccaaga ggaagaaact ttcttatctc
    12481 actatgagag tgaccaaaca ccggtttctc atgaaaagat tgctatttat aaaattttac
    12541 aagatactat ttggagtcta tggactgtat ataaggaaga gcaaggtgca gattttggtg
    12601 actatggtgt gaatcgttac caaagagctg ttaaaggttt ggcttcttat ggaggttcag
    12661 atgaaaagta aaaacggagt tccttttggc cttctctcag gtattttctg gggcttgggt
    12721 ctaacagtta gtgcttatat cttttcgatt tttacagatt tgtcaccctt tgtggtggcc
    12781 gctgctcacg atttcttgag tatctttatc ttactggctt ttcttttagt aaaagaaggg
    12841 aaaattcgtc tctcaatttt cttaaatatt cgcaatgtca gtgttatcat cggagccttg
    12901 ctagcaggtc ctattggtat gcaggccaat ctttatgcag ttaagtatat cggaagttct
    12961 ttagcttcat ctgtatcggc tatttaccct gcgatttcag ttctattggc tttcttcttt
    13021 ttgaagcaca agatttcgaa aaatactgta tttgggattg tcttgattat tggagggatt
    13081 attgcccaga cctataaggt tgaacaggtt aattccttct acattgggat tctctgtgct
    13141 ttggtttgtg ctattgcatg gggaagtgag agtgttctta gctcctttgc tatggaaagt
    13201 gaactgagtg aaattgaagc cctcttaatc cgtcaagtga cttcgttctt gtcctatctt
    13261 gtgattgtgc tcttctctca tcagtcattt gttgcagtag ccaatggaca attgctaggt
    13321 ctcatgattg tctttgtagc ctttgatatg atttcctact tggcttatta tatcgttatc
    13381 aatcgcttgc aaccagccaa ggctacaggc ttgaacgtga gctatgtagt atggacggtc
    13441 ttgtttgcag ttgttttttt gggtgcaccg ctagatatgc tgaccattat gacgtcactt
    13501 gtcgtcattg ctggagttta tattattatt aaagaataaa ggagattcgt gtgaaagcca
    13561 ttatcttagc agcgggattg ggaactcgct tgcgtcctat gactgaaaat acccctaaag
    13621 ccttggttca ggttaatcaa aaacctttga ttgaatacca aattgagttt ctcaaagaaa
    13681 aaggaatcaa tgacatcatc atcatcgttg gttatcttaa agaacaattc gattatttaa
    13741 aagaaaaata cggtgttcgc ctcgttttca atgataaata cgctgactac aataactttt
    13801 actctctcta tcttgtaaaa gaagaattgg ccaacagcta tgttattgat gctgacaatt
    13861 atctctttaa aaatatgttc cgcaatgatt tgacacgttc gacttatttt agtgtttatc
    13921 gtgaagattg taccaacgaa tggttcttgg tctatggaga tgactacaag gttcaagaca
    13981 ttattgttga tagcaaggca ggtcgcatcc ttagtggtgt atccttctgg gatgcttcaa
    14041 ctgcagaaaa gattgtcagc tttatcgaca aggcttatgc aagtggtgaa tttgttgatc
    14101 tctattggga caatatggtt aaggataata tcaaagagct agatgtctat gttgaagaat
    14161 tagaaggcaa tagcatttat gagatcgata gtgtccaaga ctatcgtaaa ttagaagaaa
    14221 ttcttaaaaa cgaaaattaa agattccaac atctgacaaa atagtcggat gtttttttga
    14281 ttttttacga acttttacga atagatagat gagtagaaaa agaaatggag ttatttatga
    14341 aaattacaaa ctatgaaatc tataagttaa aaaaatcagg tttgaccaat caacagattt
    14401 tgaaagtgct agaatacggt gaaaatgttg atcaggagct tttgttgggt gatattgcaa
    14461 atatatcagg ttgccgtaat ccagccgttt ttatggaacg ttattttcag atagacgatg
    14521 cgcatttgtc gaaagagttt caaaaatttc catctttctc tattttagat gactgttatc
    14581 cttgggattt gagtgaaata tatgatgcgc ctgtactttt attttacaag ggaaatcttg
    14641 acctcctgaa attcccgaag gtagcggtcg tgggcagtcg tgcttgtagc aaacagggag
    14701 ctaaatcagt tgaaaaagtc attcaaggct tggaaaatga actggttatt gtcagtggtc
    14761 tggccaaggg cattgacaca gcagctcata tggcagctct tcagaatggc ggaaaaacca
    14821 ttgcagtgat tggaacagga ctggatgtgt tttatcctaa agccaataaa cgcttgcaag
    14881 actacatcgg caatgaccat ctggttctaa gtgaatatgg acctggcgaa caacctctga
    14941 aatttcattt tcctgcccgt aatcgcatca ttgctggact ttgtcgtggt gtgattgtag
    15001 cagaggctaa gatgcgttca ggtagtctca ttacctgtga gcgagcaatg gaagaaggac
    15061 gcgatgtctt tgctattcct ggtagcattt tagatggact atcagacggt tgccatcatt
    15121 tgattcaaga aggagcaaaa ttggtcacca gtgggcaaga tgttcttgcg gaatttgaat
    15181 tttaaaaatg acctaagcta gaattctaag aaaaaatcaa ttttaagaga aaatgaaccc
    15241 aacatttcca taataaaacg catattagca agtttttaac acttgataat atgcgttttt
    15301 tctaagtgga ttagtagagt agaggatttt tctcatataa tactcttcga aaatctcttc
    15361 aaactacgtc agcttccatc tgcaacctca aaacagtatt ttgagctgac ttcgtcagtc
    15421 ttatctacaa cctcaaagca gtgctttgag caacctgtgg ctcgcttcct agtttgcgct
    15481 ttgattttca ttgagtataa gggaaagtat agtgaattga aataagatgt gaacaactct
    15541 atcaggaaag tcaaattgat ttatagaaat attttagcag ccaaggtgca ctgttataga
    15601 ttcaatacac tataatttag tgtaattgag aaaggagaaa tgattgtgat tgatgttggc
    15661 taggttatgt tcaatgattc ctaccgtctc aaatcttgtc agtaaggaaa aataaattct
    15721 tcaaaagtag agattacaag gcttgtttaa gaaagaattc aaagaccttg acaaataaaa
    15781 ataaaatggt tattataaaa aatggtctga aatagatgat gatacttttc gaaaatcttt
    15841 ttacgtcagc tcagctttgc cttgctgtgt tttgagcaag ctacggttag cttccgagtt
    15901 tgattttcat ttactagaaa tgaaactgat gagagatatc agtagacatc tgagttagga
    15961 tattatggaa aatgataaaa agagctcgtg agattggcat atcagactac taaagtattg
    16021 agtttgttag gattttagcg actagttagc tgggaaagga agatatttgt gacaaataat
    16081 aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga actttccaga
    16141 agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt aaatatggat
    16201 tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc tattctggga
    16261 gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt taaaatatta
    16321 gctattcaaa ttcttgccag tctaatagct tcaacacttt atttttatct ttctcccatt
    16381 tcgtatgcta gttcggagat tgttgctaga acctctccga ctatttggga tgttctcatt
    16441 gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac caataatatt
    16501 gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt aggttatgct
    16561 attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct catcaattgt
    16621 agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa gaaacattat
    16681 tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt tgctgttttg
    16741 ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt gaaaaaagag
    16801 tcccttaaga aatttatatc agagcagttt caggggtata atattttgaa aaaaacctat
    16861 tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac agaagaagaa
    16921 ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt
    16981 tcacaattgt ctgattcaga acaacttagt aaggaagagc tggtggagta tttcttccag
    17041 tatatcaagg ataaggaagc aaaagaaaag gagaaagcta ataaatttga tacagagtct
    17101 gaggagcaat aatttcttga gaatagctgg tttctctcgt gagtcttcta tgtatatcaa
    17161 aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta agtcttgaca
    17221 gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt gtgatactgt
    17281 ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca tcgtggagtc
    17341 gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg ttttagccag
    17401 tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg aaaataatta
    17461 tgaaccgcaa tatattaata tccgaggaaa aggccctctt atcaatgact tgaaaaaaga
    17521 agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag gagaagcgat
    17581 ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt
    17641 caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat
    17701 ggacttggtc gatgcccaac aagctcgtcg gatcttggat cgcttggtag ggtattcgat
    17761 ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat
    17821 tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc cagaagaata
    17881 ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg
    17941 agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag tcttgtctcg
    18001 tctgacgagt aaagactttt cagtagatca ggtggataag aaagagcgca agcgcaatgc
    18061 tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa tcaatttccg
    18121 tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata tcggttctgg
    18181 tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc ctgtagcgca
    18241 aaatgaggcg gcaagcttca ttacggatcg ttttgatagt aagtattcta agcacggtag
    18301 caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc cgtcaagtgt
    18361 ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca agctatatac
    18421 ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg ataccatggc
    18481 tgttaaattg tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg ttaagtttga
    18541 tggttatctt gccatttata atgattctga caagaataag atgttaccgg acatggttgt
    18601 tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc aaccgcctgc
    18661 ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg gacgtccatc
    18721 aacctacgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc tggcagccaa
    18781 acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg aatatttccc
    18841 agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg atgtcgaagt
    18901 tggaaaagag cagtggcgac gggtcattga tgccttttac aaaccattct ctaaagaagt
    18961 tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag ctggatttga
    19021 ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta aattctacgc
    19081 ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga
    19141 gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta atcgcctatt
    19201 ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc ctgttggtcg
    19261 tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca
    19321 ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg aggggcccga
    19381 aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt tatgcgaaac
    19441 tagaagaaga ttattttata ctcaatgaga atcaaagagc aaattagaaa gctagtcgca
    19501 ggttgctcaa agcactactt tgaggttgaa gatggaagct gacctggttt gaagagattt
    19561 tcgaagagta ttaactagga gaagttatgc gtcttatcta tttgataatt ggttttttat
    19621 cactggcctt ggctattgtt ggggttgttt tacccttgtt gccgacaacg cctttccttt
    19681 tgttgtctat tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata
    19741 ccaagctcta tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac
    19801 gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt tattttgcac
    19861 ctcttttacc agtcaaaatc ggtctgggtg ctttgaccat ctttatcact tattatctct
    19921 tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga
    19981 aatcatattc ataacaatat gatataataa atttgaagta atattcaagg agaatcaaat
    20041 gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaggcgatgc aggctggagc
    20101 tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt
    20161 gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg
    20221 gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat
    20281 tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggagctttaa ctgctgataa
    20341 aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt
    20401 ctttcacatg gcctttgatg aactaagtga tgaagatcaa ccggaagcta ttgactggct
    20461 cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga
    20521 aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct
    20581 accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg tgggggtaac
    20641 acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct agctttgggt
    20701 agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc
    20761 atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag
    20821 gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc
    20881 aagagactgg tgacctctat cctcacgttc atatggaaag catgagggga agttttgtcg
    20941 gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct tgttttgatg
    21001 tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg
    21061 gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag
    21121 gcaatcaaaa gtggtatgcc gtcttgatga gaatctcttg gaataagctg gaaaagggta
    21181 gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac
    21241 aaaaggggat ttatccagcc tttcatatga gcaagcgcta ctggattagt gtgtcccttg
    21301 atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct
    21361 ataaaaaatg aaatatttta ataattttca tgaactttca attagctaaa tattctttac
    21421 tgaagaaatt ttcagaaaat ataggattta ccacaccaga ggaatatggt gccatcttca
    21481 aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg
    21541 atgacctcgg aatggcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg
    21601 ttgaagggac tatcaatggt attagggagc gagctggaaa tgctgctttg gaagaaattg
    21661 cagtggctct caatattcgc caagattact accaagtaga aaccagtatt gtcctaaatg
    21721 agaccatcaa tacgtcagaa atggtttctc gcttctctgg tattccagtt cctaaaaaca
    21781 aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa gatggagtcc
    21841 ttaaaaatcc tctcacttat gagatcatca cacctgaatt ggttggtgtt aagattccgc
    21901 ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt
    21961 ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggtc gataagaagc
    22021 aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt gaaaatccag
    22081 aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc
    22141 tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt
    22201 ccgttgaagc aatctttaac gctatcgata agttctttaa ccaatctgtt cgtttggtgt
    22261 cctacactat cgatgcggta acagatggaa tcgataccca ggatcgggtt ttggtcactg
    22321 ttgaaaacag agatacagaa accatcttta atgcagcagg gcttgatttt gatgtgttga
    22381 aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg
    22441 agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga aggctatggc
    22501 aaagaaaata gtagctctag caggagacgg aattggccca gaaatcatgg aggttggttt
    22561 agaagttctg gaggctctag ctgaaaaaac aggttttgac tatgagattg acagacgacc
    22621 gttcggaggt gcagatattg atgcagcatg gcctccctta cctgatgaaa cccttaaggc
    22681 aagtagggaa gcagatgcta tcctactagc agctatcggt agtcctcagt atgatggagc
    22741 agtggttcgc cctgaacaag gcctgatggc tctccgtaag gaactcaatc tttacgctaa
    22801 tattcgtcct gtaaaaatct ttgacagtct aaagcatttg tcaccactca aactggaacg
    22861 aattgctggt gtagactttg tcgtggtgcg tgaattgaca ggcgggattt actttggaga
    22921 tcatattctt gaagagcgca atgcgcgtga tatcaacgac tatagctatg aggaagtgga
    22981 gcggattatt cgcaaagcct ttgaaattgc aagaaattgc agaaaaatcc ttactagtat
    23041 cgataagcaa aatgttctag cgacctcaaa actctggcgg aaagtagctg aggaagtcgc
    23101 acaggatttc tcagatgtaa ccttggaaca ccagctggta gactcagctg ctatgcttat
    23161 gattaccaat cctgctaagt ttgatgttat tgtaacggag aatctttttg gagatatttt
    23221 atctgatgaa tcaagcatct tatctggtac acttggggtt atgccatcag ccagtcattc
    23281 tgaaaatgga ccaagtctct atgaacctat tcacggttca gcacctgata ttgcaggtca
    23341 aggaattgcc aatcctattt ccatgatttt atcagttgtc atgatgttga gagatagttt
    23401 cggacgttat gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc tggcggcagg
    23461 aattttaacg agagatatag gaggtcaggc ttcaacaaag gaaatgatgg aagctattat
    23521 tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc ttttgatttg gaatgtcatc
    23581 attttcttga tttatggcat tgacaaattc aaggcaagaa gaagagcttg gcgcatccaa
    23641 gagaaaatct tactcatttt agcccttact tgtggtggtt ttggggcctg gttagctgga
    23701 atcacttttc accacaagac tcgaaaatgg tactttaaaa cagtttggtt tcttgggatg
    23761 gtgaccacac tagtagcctt atattttatt tggaggtaat ggatggcagg gtcttcgagg
    23821 gaacacgctg cttgggctct agcggactat ggttttaagg tcgtgattgc aggatctttc
    23881 ggtgacattc attacaataa tgaactcaat aatgacctgt tgccaatcgt tcagcctaga
    23941 gaggttagag agaaactagc ccagctaaaa ccaaccgacc aggtaactgt ggacttggaa
    24001 caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg agatagatag cgagtggaaa
    24061 cataaactcc taaatagttt ggatgatatc ggtattacct tgcagtatga agagttgatt
    24121 gctgcttatg aaaaacaacg accagcctac tggcaggatt agaaaaaata gaaaaggaaa
    24181 tatagtaaac tgaaataaga tgtaaacaaa tgaattagag cttaacatcc atttccagca
    24241 attttttaga aactacagtg gactattctg gattcaacac attataaaat tatgacaaaa
    24301 cacattcaca agaaggctac gacattttaa aaggtgaggg cggatgtatc gtttgcccta
    24361 ctaaagttgg ttacattatc atgaccagtg acaaggcagg acttgagcgt aagttcgcag
    24421 ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg cggtagcatg gatgaacttc
    24481 gcgctttagc gcaactcaac ccagaaattg aagcattcta ctaaaaacat tgggatgaag
    24541 atattcttct tggttgtatc cttccttgga aaccagaagc ctctgaaaaa ctcaaagcat
    24601 acggggatgg ccgtgaagaa cttatgactg atgtacgtgg tactagctgt tttgttatca
    24661 agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt aaaatggtct
    24721 acgcctcatc tgcttcaatg acaaaacgat tgaaactcgc tatgagagca aggtgtaatg
    24781 gtgtctatgg ttgataagga cggcaaactc atcccagaac aaggaggagc acgttcaact
    24841 tcaccagcac cagttgtgat ccgtaaaggg cttgacattg atatagtaaa atgaagtaag
    24901 agcaggacaa attaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
    24961 tgtactattc tagtttcaat ccactataaa atcatgatgc acctgtcaga tacttttaac
    25021 tcatgggact accgtcaggt tgagtattat taggatagag aagaagtcta gtgttaagga
    25081 cattacagct cataatacta ggctttttta tagaaattct tttctttttc tataggatat
    25141 ggtattctat gtagaaaata tatgttaata agtaatgcca atatttaaac atcattagta
    25201 aaaggagtta gattgatgaa taaaagaaaa gttagtttag aagattttta taaatggtat
    25261 agtctaaata aagaagagtt attaaataag gcaactgttg gtgaaaagtt taatgataaa
    25321 ttaaaagaag agtttctcca ggaatggcct ttggatagga ttttaacaat gtcaatcgat
    25381 gaatatgtaa taggaaaggg acagcaaaat aagtctttat gctacgctct tgagaaggga
    25441 aaatacaaaa atctatttct tggaatttct ggtggctcag cttcaaaatt tggtatttat
    25501 tggaataaaa aaacaaacaa atataaagat caagctaata atgagatttc agagttggat
    25561 cagcgatttt caaaattaaa atcagatttg tatgaaatta tcaaagaagg tattcgtttt
    25621 aactttgaaa atcctatttt tgatatgaaa agatcaacaa atgaatttat tggtcgttct
    25681 gctatggtga caaaattact ttgtatctat actgagggag atcctttctt tggtgtaaat
    25741 attaatagtc agaaagaatt ttggaaccac tttgtttctc agacaaatca aggtggacct
    25801 tatctgcaaa atcataaaat aattgaactg gtgtccaaaa cttatcctga gttggagcca
    25861 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
    25921 aatagtacaa tggattcatc aaacaatttt agtcatcaat taactcaatc tctattaaag
    25981 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
    26041 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
    26101 tcctatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
    26161 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
    26221 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
    26281 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
    26341 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
    26401 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
    26461 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
    26521 gaaattgata ctgataagaa attcgtcttc atcatcgatg aaatcaatcg tggggagatt
    26581 tctaagattt ttggcgaact ctttttctct atcgaccctg gctatcgtgg tgaaaaagga
    26641 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
    26701 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
    26761 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
    26821 gataaagagc tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
    26881 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
    26941 aagttgaagg atgtagattt tgactatgaa ttactctggt ctgattatat taagcctctc
    27001 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
    27061 gcatttgaac tgacaaataa tgagcaaaaa gatcaggcag tagctgatga caatgaaagc
    27121 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
    27181 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
    27241 agatgaacgt attttcattt ttccaaatga tttgactcat actccagatt tggataagaa
    27301 acaaaagatt ttggaaacga tcaatcagga aatcaagaca ggaaatgtga ttggttttct
    27361 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
    27421 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
    27481 tttgtctcgt gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca
    27541 agctgctatt cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtca
    27601 tgttaaggga gtgattgatg taagaaacca tctcaagaaa aaccttcctt taacgggaaa
    27661 tattgcctac acaacgagag agttcaccta tgataatccc ctcatgcagt tgatttgtca
    27721 tactattgaa tacattaaga atcagaaaag cattgggcaa ggagttcttg atagtctctt
    27781 aactagtcgt gaaaatgtat ctgaaatcat gcgagtaact ccatcttata aactagctga
    27841 tcgtgcgaag attattcggg gaaataaatc taaacctata cgtcatgcat actttcacga
    27901 gtacagaaag ttacaagaac tttgtctgat gattctaaac caagaaaagc acggtttagg
    27961 ctatcaagat caaaaaattc atggtattct ttttgatgtt gcctggcttt gggaagagta
    28021 tgttcatact ttgttgccaa aagatttcat ccatccacga aataaagata agacggacgg
    28081 aatttcagta ttttctagtc gagaacgaaa agtttatcca gatttctata atagagattt
    28141 aaaaattgtg ttagacgcta aatataaaaa gcttgaagat actgaaaaag gaataaaccg
    28201 tgaggacttg ttccaactga tttcctattc ttatatttta aaagctgaga aggctggtct
    28261 tatttttccg agtgagaaaa aggcggttga taatgagata ggaaagctag cagggtacgg
    28321 agccttatta aagaaatggt ctattcaaat tcctcagaac tcttcatcct atcgtgaatt
    28381 ttgtgaaatg atggaaagat ccgaagaatc ttttaaaagg aatattacta aagaactggg
    28441 gagaaaataa tctctccgct ttcttttgtt attcatccaa taaaatccga acgatatatt
    28501 ttaatttata acattatttg acaaaaactt tactttagtt tataataaat taaggaaacg
    28561 tcggaaaaga cgtagagatg cgcaagcata tgtaggtcat tataaaagaa acgagacatc
    28621 gatatgttaa atgaatttcc aatttttgat tacgaagata ttcaattgat tccaaataaa
    28681 tgtgtgatta aaagccgtgc agaagcggat acaagtgtca ctctaggaaa tcacaccttt
    28741 aaactacctg ttgtgccagc taatatgcag acgattttgg atgaaaatgt agcagagcaa
    28801 ctggctaaag gtagttactt ctacattatg catcgttttg atgaggcagg acgtattcct
    28861 tttattaagc gtatgcatga gcaagggctc attgcgtcca tttctgttgg tgttaaggac
    28921 tatgagtatg atttcgttag ccagctcaag gatgatgctc cggaatatat cacgattgat
    28981 attgcccatg gtcatgcgga tagcgtgatt tctatgattc aacacatcaa gaaagaattg
    29041 ccagatacct ttgtcattgc tggaaatgtg ggaacaccag aagctgtgcg tgaattggaa
    29101 aatgctggtg cagatgctac taaggtcgga atcggtcctg gtaaggtttg tatcaccaag
    29161 gttaagactg gttttggtac aggtggttgg cagttggctg ctctacgctg gtgtgccaag
    29221 gctgcgcgta aaccgattat cgctgatgga ggaattcgta ctcacggtga tattgccaag
    29281 tctatccgct tcggtgctag catgatcatg attggttccc tctttgcagg acacattgaa
    29341 agtccaggga aaacgattga agtcgatggt gaacagttca aagaatatta tggttcagcc
    29401 tcacaatatc agaaaggtgc ttacaaaaat gtggaaggca aacgtatctt gcttcctgct
    29461 aaaggtcatc tgcaagacac tttaactgag atggaacaag accttcaaag tgctatttct
    29521 tatgcaggtg gacgtcaggt tgctgacctt aaacacgttg attatgtgat cgtgaaaaac
    29581 tccatctgga atggggatgc ttcccactaa gacggggtct ttgaccaaaa aacttgttat
    29641 tagagcaaat ttctgttata ataaaacaag tttccaccct tagtgtaatg gatatcacgt
    29701 aagattccgg ttcttgagat gggggttcga ttccctcagg gtggatgtaa acatcctaaa
    29761 aagcctttaa tagggctttt ttctttacac tgctttaaat ttgtccctaa tactcaatga
    29821 aaatcaaaga gcaaactagg aagctagccg taggctgctc aaagcactgc tttgaggttg
    29881 tagataagac tgacgaagtc agttacatat acctacggca aggcgaagct gacgtgattt
    29941 gaagagattt tcgaagagta taaaactgaa aatctctgtc taaagaattt ccaaatcccc
    30001 tccagtcccg ttttaaagtg actcaggggg cttttt
//
LOCUS       DAVFJR010000025        29541 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVFJR010000025 DAVFJR010000000
VERSION     DAVFJR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.026"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            129..809
                     /locus_tag="VU722_001362"
     CDS             129..809
                     /locus_tag="VU722_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772324.1"
                     /translation="MYNQKLIKMVKGLFVGFIAVLCIILGYSIAQVQQNLRQNSQVQE
                     EAKQKPEEKQQEQLSLTEQQVEEFLIAYYTKKDLEENRPRYKPFMTDSMYQETVQEEQ
                     KPVNQTYKGYVVDQAFESGSIYIDKQHKIALAQVQYTSTTLTEKDNRASKGLTGSTKA
                     TIRLTYVEKAGKLLINKIEPIVLTEARGQSVGTYADTSSSSSTPVSSTSTATPTSSEP
                     TTATSSNQ"
     gene            820..1059
                     /locus_tag="VU722_001363"
     CDS             820..1059
                     /locus_tag="VU722_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772325.1"
                     /translation="MNKKIEQLEGKLEKVRKDKEKAQRQKEEADKKIKNYINQEKDLE
                     AQLFVALSEESGLSYQEMKELILPAQSSNQGVNHV"
     gene            1052..1951
                     /locus_tag="VU722_001364"
     CDS             1052..1951
                     /locus_tag="VU722_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772326.1"
                     /translation="MYKIINQLTNQEETFEYRDDLLSRLEIINERMKSNKINGIYRLY
                     SLNSEGEILQEESLEIPFVGIIDQLLENFGMSAGKKKKGLLHFLEKHKEKNSSLGTPE
                     IQLQPEFQPEPDPELEDLTVTKEANMARQIIAELVSQKPRDEVREEVPLEDKMTYSSS
                     EWTTDHFSRLDENEEERVEPSQDMPTQEVVSIVEKSTQEEKIPLSVKEDKGNVETSFS
                     LSHVTSVNLPSEVIDSFEAQTVTYKQSIKHKIQSNEEFIKEANEEINECQNKINELRQ
                     QILAKEKQASQLKDLYFKIEEVS"
     gene            1953..2501
                     /locus_tag="VU722_001365"
     CDS             1953..2501
                     /locus_tag="VU722_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772327.1"
                     /translation="MEQEQVVAQLGRATLVTGEIILKGLFLVSSKAVEMYQARGENVL
                     FTGETDWNKFMATADTKEVQQLLNNEVNLEAVRKELGQYGIGFSFYTHPDGKTTLAFN
                     AKDKGVVEQAFKDVLEGITRDPRGFNERNLKNGKTTSFEEKLQHFKAVEQEKISSLQV
                     NIHTKEFVLSENIEPQIGGKMK"
     gene            2498..4333
                     /locus_tag="VU722_001366"
     CDS             2498..4333
                     /locus_tag="VU722_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU1772328.1"
                     /translation="MITEKKKRRLRPYLLLGIGLFYFFHWLFKLWLLAPDTDSVTDVF
                     GLGKLNWMSDHLNDKSWFDFQFTPTSLLIGMSGFLIAFLLYLRVTDTGTYRYGEEHGS
                     ARFATREELMRFRDEEPEKNMIFTQNSQMGLFNNRLSFENQINKNILVYGGTGDSKTR
                     SAVKPNILQGNSSFVTTDTKGILIHETGKSLVEKGYKMKIFDLITFLNSDGFNVFRYI
                     HNEMDIDRVAEAITESLNRNGHESDPFWPAANKLLMRSLIGYLYFDGQIDHYLPNLGQ
                     VTDMIRELRRNHPEAESPVELMFEDLERRSPGNYACRQWKLFNKNFDGQTRTSVYAIF
                     ATTFSVFDHEQLRKIIEKDTLEIEKWNIEKTAVFIHIPEVDPAYQFLSALLFSTVFDV
                     LIKTADAVILGEHPTKIKEDLLHLQVWADEFGQIGKIPNLPPIISVIRSREISIKMMV
                     QSQSQIEVLYGKENTKTIINNCGAILYLGSNDLDTLKYLSERSGKQTLNDQNYSESRG
                     RNASSSKQNSKIGRELLTPHEVATIGTTEALLFLSKQNVFRDQKFNLDTHPRAYLLSN
                     GSNDDNWYRYKRYLSDIDEWKAQVGEENVIYIGIKEVEEVPLKVS"
     gene            4674..5081
                     /locus_tag="VU722_001367"
     CDS             4674..5081
                     /locus_tag="VU722_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772329.1"
                     /translation="MKSTIKNYYEMWTKRHERRYREALGYYNQQSKEALLAELTELEI
                     KKERSSRSWKLLVGLVLTIIFSDDLKRLLAILFSPLTGVPTNKLHESVLPSISIALFI
                     VLLFLTILIYNFSYSLLLRRYLILKRYIEEHYT"
     gene            5097..5570
                     /locus_tag="VU722_001368"
     CDS             5097..5570
                     /locus_tag="VU722_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772330.1"
                     /translation="MYRDRFFEVLESPYTPYVAIELIYAIVVICFNLNLGNLNKQLTH
                     HFDIDKMINQKDVSIASNVMSYENNISWHFLFFGILLIIIGFIIPILFSIINKSSYKR
                     EEIKNAIWFIIAIVIVVNFFLIISISRALLSPIIIATLIVCAVGATLGSLAISNT"
     gene            5845..7194
                     /locus_tag="VU722_001369"
     CDS             5845..7194
                     /locus_tag="VU722_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772331.1"
                     /translation="MNTLPQKQFKRMKREVEEETARGIGYFEGILEHIPSYPLSEAVK
                     ELALSGWITPHTDVIDVQNMIVTESIKWMNYQDFKEVAPYLFSYPREQREKDLLVQPV
                     KISREYFEELKANAEELFHLKQDLLQVNNQLDAKIQELEMDQLPNGDQVIGVDLKAEE
                     VLLLRTPENAQVEEWEVRKDGLITDYRSNLSEYAQIVDALLEMENPEIDTILYEEVIN
                     YSKKTWPDSEPIQLPENIKELLNQEGKLDPSYYQIAQFETVKQAYIYGMISPSFQERF
                     PHYSDFIRNYVEDREQYEFFNYRTEAVSLAQEILVPRLGDINQILGTNNQELIVQEVV
                     GYSQGESWELAYLRDTKTEDRESVRFYLESEIGAWYKGSLTELAVIRFEDIDLEKGFN
                     GHQEAVYHIDENLLVQDKLKQAQLHFPDLKHFVEAEELEREQTQDIVAEKEEPEFSL"
     gene            7206..8468
                     /locus_tag="VU722_001370"
                     /pseudo
     CDS             7206..8468
                     /locus_tag="VU722_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            8472..9333
                     /locus_tag="VU722_001371"
                     /pseudo
     CDS             8472..9333
                     /locus_tag="VU722_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730738.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim"
     gene            10636..10944
                     /locus_tag="VU722_001372"
     CDS             10636..10944
                     /locus_tag="VU722_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772332.1"
                     /translation="MIEHLKQETFDLLMEIFFEDEATDSPKVNEVNQHISRKECLYIL
                     RRDMRIKTNYELEEVEMYPIVLKEIEGMSDERFEQLRDEILKMEMVDTMELILEDLKV
                     "
     gene            11167..11535
                     /gene="mobC"
                     /locus_tag="VU722_001373"
     CDS             11167..11535
                     /gene="mobC"
                     /locus_tag="VU722_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEU1772333.1"
                     /translation="MENGEKRKRPVQKLIRLTEEENRFISTKVAESGMTNFNAFARIM
                     LIMGEVKILNFEELRELRKEINRIGVNINQVAKKVNEDDQASLTELSQILELQKYLKD
                     TVSQFIQKQENQTKEQERWL"
     gene            11526..13202
                     /locus_tag="VU722_001374"
     CDS             11526..13202
                     /locus_tag="VU722_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU1772334.1"
                     /translation="MVVTKVLQIKGVASLGRSTKYIEDEAKTVELTDTKSLNNALRYI
                     ENPSKTSFLEQDEQFEFPAVVKDGRVVKQLVSTYGITDASTATEEFLLTKKNAAQRAG
                     TKERSDIHNPNRVLAHHIIQSFSPEDDWTPQEIHEIGRKTILELTGGQHEFVIATHMD
                     KGHIHNHIIFNSTNSVTLKKFRWQKNTARSLFNISNKYSDLAGAKILKERLWTNRKTY
                     HAYRKKNSFRYEIKSRLDFLLKHSTSLEDFKIKARALNLEVDTSGKEIKYLLTDRDQT
                     RNVRDRTLSKKGNYSLEKISEKVVANEVTLSVDEIKSEYEKMVAEREDDFEMRITVEE
                     WQVMEETKNGIYLEMEFGLRNKGTILIPAHQIERAEDGSYEIFIRKNDFYYFVNPEHA
                     DKNRYMKGETVASQLSYDNGEMIIRKNPKISTLDQLVREYNYLSAHGVTEGQQFDELL
                     NRFEEELEEVDNLLDKLDQRLGELNKIQSAFLALESSDPQEVKLAIAIMKDLRVDPST
                     RKSEIDKLVKEATFERQTLYQRVEAITKDYKLHQDIEKNVEQRKEIETSL"
     gene            13278..14084
                     /locus_tag="VU722_001375"
     CDS             13278..14084
                     /locus_tag="VU722_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEU1772335.1"
                     /translation="MKIITFAAIKGGVGKTTLTFNYGEWLARKGHNVLFIDLDHQCNL
                     TQCYNIYESQNTIANAFKGGDVDIKHIKENISLIPGSVQLDTVERDLENSDKKNMLLY
                     LWLEDNYEKKKLGQFDYILIDCRPDFATATKNAVAVSHAIISPLTPSEFGYNAKFNLS
                     TRLEAFRKDVIDYRTRESYITAELYFLANMIRPNYGSSRELLEALGLEAKEKGTDNLL
                     GIVPAKELFNHSTIDKVSIADMKEKPDLYQKHKKFFMELEETFSRIYDTI"
     gene            14137..14358
                     /locus_tag="VU722_001376"
     CDS             14137..14358
                     /locus_tag="VU722_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772336.1"
                     /translation="MAFTPKEKEISQIIEATHQPEQLPDIDSFESFERKKQFQFTLKP
                     SNRKKLDQVAKAAGAKSASDYLDKLIEKL"
     gene            14423..15199
                     /locus_tag="VU722_001377"
     CDS             14423..15199
                     /locus_tag="VU722_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEU1772337.1"
                     /translation="MDLITRLLAEREGKVHGGIYDITQKRFAYNSNRIEGSRLTEEQT
                     SLIYETKTIANIDAKGIKIDDLVEMNNHFKCFDYILDTVNEPLTEDHIKTLHRVLKSG
                     TSSEHNPIAPVGRYKVLQNEVGKIATASVEQTEDEMLSLLIGYDLKKQKDLNYLTSFH
                     AQFERIHPFADGNGRIGRLLLYKQCLKEGLTPFIVDDINKATYYSALEAFQVHDNRQL
                     LFDYFQSEQLFYMNYLKNKGFEGAINDEKEGDFIKKSDKF"
     gene            15578..16899
                     /locus_tag="VU722_001378"
                     /pseudo
     CDS             15578..16899
                     /locus_tag="VU722_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397931.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISLre2 family transposase"
     misc_feature    17277..17408
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            17424..17954
                     /gene="infC"
                     /locus_tag="VU722_001379"
     CDS             17424..17954
                     /gene="infC"
                     /locus_tag="VU722_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU1772338.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            17987..18187
                     /gene="rpmI"
                     /locus_tag="VU722_001380"
     CDS             17987..18187
                     /gene="rpmI"
                     /locus_tag="VU722_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU1772339.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            18239..18598
                     /gene="rplT"
                     /locus_tag="VU722_001381"
     CDS             18239..18598
                     /gene="rplT"
                     /locus_tag="VU722_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU1772340.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            18656..19036
                     /locus_tag="VU722_001382"
     CDS             18656..19036
                     /locus_tag="VU722_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1772341.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLESLHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            19286..20086
                     /locus_tag="VU722_001383"
     CDS             19286..20086
                     /locus_tag="VU722_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU1772342.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKVNKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            20097..21035
                     /locus_tag="VU722_001384"
     CDS             20097..21035
                     /locus_tag="VU722_001384"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU1772343.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKTILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENFPKVMDKYGISSLEELRQEVKESLR"
     gene            21077..23110
                     /locus_tag="VU722_001385"
     CDS             21077..23110
                     /locus_tag="VU722_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU1772344.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAADEWVFDTHYQSWFYIKADANYAENEWIKQGDDYFYLKSGGY
                     MTKSEWVEDKGAFYYLDQDGKMKRNAWVGSSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDRQYQSWFY
                     IKENGNHADKEWIFENGHYYYLKSGGYMAVNEWIWDKESWFYLKSDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKN"
     gene            complement(23171..24826)
                     /gene="pavA"
                     /locus_tag="VU722_001386"
     CDS             complement(23171..24826)
                     /gene="pavA"
                     /locus_tag="VU722_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU1772345.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMILRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMRKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHRVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            24931..25428
                     /gene="ybeY"
                     /locus_tag="VU722_001387"
     CDS             24931..25428
                     /gene="ybeY"
                     /locus_tag="VU722_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU1772346.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMFEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            25409..25804
                     /locus_tag="VU722_001388"
     CDS             25409..25804
                     /locus_tag="VU722_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU1772347.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            25821..26720
                     /gene="era"
                     /locus_tag="VU722_001389"
     CDS             25821..26720
                     /gene="era"
                     /locus_tag="VU722_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU1772348.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKATKVPVILVVNKIDKVHPDQLLSQIDDFRNQIDFKEIVPISALQGNNMSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDCMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            26769..27593
                     /gene="mutM"
                     /locus_tag="VU722_001390"
     CDS             26769..27593
                     /gene="mutM"
                     /locus_tag="VU722_001390"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU1772349.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LTSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKAGQACSRCGTVIEKFQLGGRGTHFCPNCQRRD"
     gene            27593..28198
                     /locus_tag="VU722_001391"
     CDS             27593..28198
                     /locus_tag="VU722_001391"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU1772350.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRKQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            28185..29384
                     /locus_tag="VU722_001392"
     CDS             28185..29384
                     /locus_tag="VU722_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU1772351.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVSFMSIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNETALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            29384..29533
                     /gene="rpmG"
                     /locus_tag="VU722_001393"
     CDS             29384..29533
                     /gene="rpmG"
                     /locus_tag="VU722_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1772352.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
BASE COUNT         9807 a         4844 c         6462 g         8428 t
ORIGIN      
        1 acgttaatag cgatggtagt ttcttagttt cagaaatgaa ctttggtggt ttatatgtat
       61 caagttggcg taccttgaaa ccacaatcag gtatctattt tgttacccct aaataagaaa
      121 ggaaaagaat gtataatcaa aagttaataa aaatggtaaa gggactcttt gtgggattca
      181 ttgccgtttt atgtattatc ctgggctatt ctattgctca agtacaacag aatttgagac
      241 agaatagtca agttcaggaa gaggcgaagc aaaaaccaga agagaaacaa caggaacaac
      301 tatctcttac tgaacagcag gtcgaggaat ttttaattgc ttactataca aaaaaggatt
      361 tagaagagaa tcgaccacgc tataagcctt ttatgacgga ttctatgtat caggaaactg
      421 ttcaagaaga acaaaagcca gtcaaccaga cctataaggg gtatgtggtt gaccaagctt
      481 ttgaatcagg atctatttac attgataaac aacataaaat tgctttagct caggttcaat
      541 atactagtac cactctaaca gagaaagata atagagcttc taaggggctt actggtagca
      601 ctaaggctac aattcggttg acctatgtag aaaaagcagg gaaactattg atcaataaaa
      661 tagagcctat cgtattgact gaagcgagag ggcaaagtgt aggaacctac gcagatacta
      721 gcagttcaag ttcaactcca gtttcttcta catcaacggc aacaccgaca tcttctgaac
      781 caacaaccgc aactagtagt aaccaataag gagaatggaa tgaataaaaa aatagaacaa
      841 cttgaaggta agcttgagaa agtgaggaaa gacaaggaaa aagcgcaacg acaaaaagaa
      901 gaagcagata aaaaaatcaa gaattacata aatcaagaaa aagatttgga agcgcagctt
      961 tttgttgctc tatcagaaga aagtggctta tcctatcagg aaatgaagga actaatcctt
     1021 ccagcacaat caagtaacca aggagtgaac catgtataaa attatcaatc aactgactaa
     1081 tcaagaggaa acatttgagt accgagatga cttgttatca aggctagaaa tcatcaatga
     1141 acgaatgaag agtaataaaa taaatggaat ctatcgactt tattctctca attctgaagg
     1201 tgaaatccta caagaagaaa gtcttgaaat accttttgtt ggcatcattg atcagttgtt
     1261 ggaaaatttt ggtatgagtg ctggaaagaa aaagaaaggt ttgcttcatt ttttagaaaa
     1321 acataaagaa aagaactcct cactaggaac accagaaatc caactccaac ctgaattcca
     1381 accagaacca gaccctgaac tagaagatct aacggtaacg aaagaggcga atatggctcg
     1441 tcaaataatt gctgagctag tttctcagaa gcctcgagat gaggttagag aggaagtgcc
     1501 tttggaagat aaaatgacct attcttctag tgaatggact acagatcatt tcagtagatt
     1561 agatgaaaat gaggaagaac gagtagaacc ttcacaagat atgcctacac aagaagtagt
     1621 ttctattgtt gaaaaatcaa cgcaggaaga gaaaatacct ctttctgtta aagaagataa
     1681 gggtaatgtt gagacttcct tctccctttc tcatgtgact tcagtaaatt taccttcaga
     1741 ggttattgat agctttgagg ctcagacggt tacttataag caatctatta aacataaaat
     1801 tcagtctaac gaagagttta ttaaggaagc aaacgaggaa attaatgagt gccaaaataa
     1861 aattaatgag ttgcgacaac agattcttgc caaagagaaa caagctagtc aactgaagga
     1921 tctttatttt aaaattgaag aggtgagcta aaatggaaca agaacaagtt gtagcccaat
     1981 taggacgggc aactcttgtg acaggagaaa tcatcttaaa aggactcttt ctggtgagct
     2041 ctaaggcagt tgaaatgtat caggccagag gggaaaatgt cctctttact ggtgagacag
     2101 actggaataa attcatggca acggcagata cgaaagaagt ccagcaatta ctaaataatg
     2161 aagtcaatct cgaggcagtt cgaaaagaac ttggccaata cgggattggc ttttcttttt
     2221 atacacaccc tgatggtaag acaactcttg ctttcaatgc aaaagataaa ggagttgtcg
     2281 aacaggcctt taaggatgtc ctagaaggca tcacaagaga tccgagagga ttcaatgagc
     2341 gaaatcttaa aaatgggaaa acgacttctt ttgaggagaa attgcaacat ttcaaagcag
     2401 tggaacaaga gaaaatttct tccctccagg taaacattca tactaaggaa tttgttcttt
     2461 cagaaaatat cgaaccacag attggaggaa aaatgaagtg attacagaaa agaagaaacg
     2521 aagacttaga ccgtatttgt tgttaggcat tggtctattc tatttctttc attggctctt
     2581 taaactatgg ctgttagcac cagataccga ttcagtaaca gatgtatttg gacttggaaa
     2641 gcttaattgg atgagcgacc atctaaacga taaatcttgg tttgattttc aattcacacc
     2701 aacttcttta ttgattggta tgagtgggtt tctgattgca tttctgctgt atttgagagt
     2761 aacggataca ggtacgtaca ggtatgggga ggaacatgga tcggctcgtt ttgcgacaag
     2821 agaagagttg atgagattcc gagacgaaga acctgaaaag aatatgattt tcacccaaaa
     2881 tagccagatg ggattattta ataaccgatt gagctttgaa aatcagatta ataaaaatat
     2941 tctggtatat ggaggtacag gggattcaaa gacacgtagt gctgtaaagc cgaatatttt
     3001 acaaggaaac tctagttttg taaccacaga taccaaaggg attttgattc atgaaacagg
     3061 gaaatcactt gtagaaaaag gttataagat gaaaattttt gatttgatta ctttcctgaa
     3121 ttcagatggt ttcaacgttt ttagatatat tcataatgaa atggatatag accgagtggc
     3181 agaggcaatt acagaatctc tcaatagaaa tggtcatgaa agtgatcctt tttggccagc
     3241 agccaataaa ctcctgatgc gctctctaat tggctatctt tattttgatg ggcagattga
     3301 tcactatctg cctaatttgg ggcaggttac agatatgatt cgagaattga gacggaatca
     3361 tccagaagcg gaaagtcctg ttgaattgat gtttgaagac ctggagagaa ggagcccagg
     3421 gaattatgcc tgcaggcagt ggaaactatt caataaaaac tttgatggcc aaacacggac
     3481 ttctgtttat gccatctttg cgacaacctt ctcagtgttt gaccatgagc aactaagaaa
     3541 gattattgaa aaggatacac tggagattga aaaatggaat attgagaaaa cagcagtttt
     3601 tattcatatt ccagaagtgg atccagctta tcagttctta tctgcccttc tttttagtac
     3661 cgtttttgat gtgctaataa aaacggcaga tgcagttata ttaggtgagc atccaacaaa
     3721 gatcaaggaa gatttattac atctacaagt gtgggcagat gagtttggtc agattgggaa
     3781 gattcctaat ttaccgccaa ttatctctgt tattcgttct cgagagattt ctatcaagat
     3841 gatggtgcaa tctcaaagtc agattgaagt attgtacggt aaagaaaata cgaagacgat
     3901 tatcaataac tgtggtgcta ttctttattt aggttccaat gacttagata cgcttaagta
     3961 tctatctgag cgatcaggga agcaaacttt gaatgatcag aattatagtg agagcagagg
     4021 aagaaatgcc agcagttcta agcagaactc aaaaattggt cgagaactgt tgacaccgca
     4081 tgaggttgcc actattggaa caacagaagc cctactcttt ctatccaaac aaaatgtctt
     4141 tcgagatcaa aaatttaacc tggatacgca tccaagagct tacctcttaa gtaatggctc
     4201 gaatgatgac aactggtatc gatacaagcg ctatctaagc gatattgatg agtggaaagc
     4261 ccaggttggg gaagaaaatg ttatttatat tgggattaag gaagttgagg aagttcctct
     4321 taaagtaagt taggaaagaa agggaatcta atggaatttt atgactctta ttgcgtttta
     4381 attgctataa attgggatca gtatgtgtgg ttgcattagg aaggcgaaaa aataacctgg
     4441 catgaaaatt tagctcatgc aggttttttt cgtgatttta atacagctaa aagggtagcg
     4501 gaaactcatt tattagaaac ttttggagcc ataggattct ataagattgt tggtttttct
     4561 acagatgaac ttgggtatat agaaaccaag aactagagag cacaatgtgt tttagtattt
     4621 tgtgatataa tgaatggaga ataagcgatg attgagagga gtgtaataat cctatgaaat
     4681 ctaccataaa aaattattat gaaatgtgga cgaaacggca tgaacgtcga tacagagaag
     4741 ccttgggtta ctataaccag cagtctaaag aggcattgtt agcagaattg acagagctag
     4801 agataaaaaa ggaaaggagt tctcgcagct ggaaattatt ggtaggtctt gtattaacca
     4861 ttattttttc agatgattta aaacggcttt tagcaatttt attttcacct ttaacaggtg
     4921 tacctaccaa taaattgcat gaaagtgtgt taccgagcat cagtattgca ctatttatag
     4981 ttttgttatt tttgactatt ttaatctata actttagcta ttcgttgcta ctgagacgct
     5041 atctcatttt aaaacgctat atagaagaac attatacttg aatataggag ataaatttgt
     5101 atagagatcg attttttgaa gtattagaaa gcccttatac gccttatgtg gcaatagaat
     5161 taatttatgc aatagttgtc atttgcttta atcttaatct gggaaattta aataagcaac
     5221 taacacacca ttttgatatt gataaaatga taaatcagaa agatgtgtca attgcgtcta
     5281 atgtcatgtc atatgaaaat aatatatcat ggcacttttt gttttttgga atcttgttaa
     5341 ttatcattgg ttttataata cctatattat tttcaattat aaataagtct agttataaga
     5401 gagaagaaat aaaaaatgcc atttggttta ttattgccat agtcatagtg gttaatttct
     5461 ttttaattat ttcaatatca agagctcttt tgagtccaat catcatagca actttaatag
     5521 tgtgtgcggt aggagcaaca ttgggatctc ttgcaatttc taatacctaa aagtacaagg
     5581 cagccgtaat ggctgttttt ttgatgaaag gagaatcaaa tggatttaga acaattgaag
     5641 caacgacgag atgagctgat taaagataat tgagtgggcg gatggcttaa ttaaagagaa
     5701 ggaagaaaaa ctatggtaag tgaaagtgag aacgattgca gcttctgagc tagcgagatc
     5761 ggcattggaa tctgctttac gttctgcagg tatcgtagat accttttacg gaccagataa
     5821 tagaaagaaa ggaaatgaaa tagaatgaat acactaccac aaaaacaatt taaacgaatg
     5881 aagcgtgaag ttgaggaaga aactgctcga gggattggtt attttgaggg gattttagaa
     5941 catatccctt cttaccccct atctgaagcc gtaaaagagt tggctttatc tggctggatc
     6001 actcctcata cagatgtcat cgatgtccag aatatgattg ttacagaatc tataaaatgg
     6061 atgaattacc aggacttcaa agaagttgct ccctacttgt tttcttaccc tcgagagcaa
     6121 cgagagaaag atttattggt tcaaccagta aaaatctcca gagagtactt tgaggaatta
     6181 aaggccaatg cagaagaatt atttcacttg aaacaagatt tgcttcaggt taataatcaa
     6241 ttagatgcta agatccagga attggagatg gatcagctcc ccaatggtga tcaagttatt
     6301 ggagtggatt taaaagctga ggaggtattg ttgctacgaa ctccagaaaa tgctcaggtt
     6361 gaggagtggg aggttcgtaa agatggcttg attactgatt atcgttccaa tctttcagaa
     6421 tatgctcaaa ttgtagatgc tttacttgaa atggagaatc cagagattga tactattctc
     6481 tatgaagaag taatcaacta ttctaagaaa acttggccag attcagaacc aattcaactt
     6541 ccagaaaata tcaaggaact attgaatcaa gagggcaagc ttgatccctc atattatcaa
     6601 atagctcagt ttgaaacagt aaaacaagct tatatttatg ggatgatttc acctagtttt
     6661 caggagcgtt tccctcatta ttcagatttc attaggaact atgtagaaga tagagaacaa
     6721 tatgagtttt tcaactatcg tacagaagcc gtctcattag ctcaggaaat tctagtacca
     6781 cgtttaggag atattaacca gattttagga acgaataacc aggagttaat cgttcaagag
     6841 gtcgttggtt attctcaagg tgaaagctgg gaactagctt atttacggga tacaaagacg
     6901 gaagatagag aatccgttcg attctatctt gaaagtgaga ttggagcttg gtataaggga
     6961 agtttgacag agttggctgt tatccgcttt gaggatattg atttagagaa aggatttaat
     7021 ggccatcaag aagcagtcta tcatatcgat gagaacttgt tagttcagga taagctaaaa
     7081 caagcccaac tccattttcc tgatttaaaa cattttgtag aagcggaaga acttgagaga
     7141 gaacagacac aagatatagt agcagaaaaa gaagagccag aattttcatt gtagggggat
     7201 aacagatggt gttaagcaaa gaagaagcca aaagattatc tattatttct gttgcagagc
     7261 aactaggcat ggagttaaag cgtacaggta gctatagcta taactgggta gaacatgatt
     7321 cctttgtaat agatgcaaag aaaaatgaat tttactggaa ctcaagaact gaatttggag
     7381 atgtcattca gttagttcaa accatacgag gtgtttctta caaggaggcg atgaattttt
     7441 tagaaactgg agaatttaag gcagtagatg tagaagctca gacggcctca aaagagcctt
     7501 ttagttatca cttggaaaga tatgagcgtc aggatttcag cgcctctaga cgctatttga
     7561 aggcacagag aggcctttca gatgatacga ttaacttctt tattagccaa ggcagtatag
     7621 cggaagcaat ccgaaaaaaa ggagactatt ttgagcctgt gattgtcttt aaatataaag
     7681 acaacacaag ctttttagct ggagcgagtc ttcagggaat agtagagaat cgagagcact
     7741 atcctgaacg tgggcgttta aaacaaatta tgagaaattc agacggacaa ctaggatttt
     7801 caattgatat cggaacacca aaacgtttga tctttgcgga agctccaatc gatctaatga
     7861 gctactatga gcttcataaa gatagtcttc aggatgtccg cttagtagct atggatggag
     7921 taaaagaagg aatcattagt agacggttta tggaattgta tgcagagata aatgataaat
     7981 cctatcaagt taatcagaat actgggaaag ctctagaagt agtcgctaga acaacgaact
     8041 attttaaaga tggtcagaat caagatatga ttaccttggc tgtagataat gatatggctg
     8101 gctataaatt tataactagt ctgcaggaaa aggggattcc agtacagatt gcgattccgc
     8161 ctatcgttca gagatatcag gagaaggaag attggaatga ctttctgaag ggagggaata
     8221 aatttcctaa ggagttagca cacgtttata cagtagacga aaagtcttgg tattaccagg
     8281 gcttttttga gaaggaacta gctcttgcaa aagcgcaaga gctaactgca gatgatgtaa
     8341 aagcctttgt gtcagatagg caattgacaa aggaagaagt ccgtcaagaa tatacaagga
     8401 ttgtcgatca agagaaagaa aggaaacata ctatgtcgga agtacatgaa gcaggggctg
     8461 agtatgaagt agaaaagcca gataatagtc gcttagcgca agctagacga aagctggagc
     8521 gactcaaagg agaagctgat gaggcaatta atgcggccta ttcccaccaa gcactaacaa
     8581 atgggcaacc catgaatgat aagcgaggaa gtgctagctt tatgcgtaag caagaacaaa
     8641 tagaaggtca agtcttctca aagctggatg agattaggca acaggaagag cgagtagagc
     8701 gcctggagca ccaacaacat ttgaaagaaa tggggttgaa tcgtcaggga agtggtctgg
     8761 atatgagtgt tcaaaatata cctcgaatcc gtgaagagtt agaaaaagct aaacgtgggg
     8821 agtcgttctt taccaaagct actctcaaac gctatcaaga agagttgact agagttgagg
     8881 ccatatctga acaaatgggt aaaacgagca ttcaaccagc aactcaagcc ttaattgatg
     8941 aggggctagt gaaccagtgg caaaaacaac caaatacgta ttttgtaaaa ggattacgaa
     9001 gagttgccct ggagttgact gaagaaggag agtttcaatt atcttcacaa atcaagtatc
     9061 atccgaaaac agatgaggaa agactgaagg tggatgaatt acttgccaaa caaaggcaag
     9121 aaaatgtagg attaacgccc tcgaatcagg aaaaatcaat ctcaccacaa ccagagccta
     9181 ttgaaaaaaa tcaaggcgaa gcagggtggt tagaaaaaaa ttgggacaat ctcacgtttt
     9241 cgatagaaaa taaaaaaaac agtcgtcatt gatccgacta gtatagatga gatggttgaa
     9301 aaattacaag tcaaagattc gcaagagaca ctagataatc gatacgaaaa aatttatcag
     9361 tataaccgaa aagatgagag ggatcgtgat ttggatggtg atggtatttc caattctgat
     9421 gagatgttgc agggaacaga tccatacaac ggtgcctcta accttcataa aaaacaggaa
     9481 gatagagaaa gaaggacaga tgttgaagcg gaaactggag ctattataac cgatgcaatt
     9541 gctactaaaa gttcagaaca aaccatttcc cagttagtcg caaataaaga tacaaaagct
     9601 ttagctgaac acttgaaaga aggaatgaag aactacttgg attcagaaca gtttaaatca
     9661 ttcttggata cgatgagtaa gtttcacaac tactcactca ataatattca tttgctgaag
     9721 atgcaaaatc ctaatgtttc ccaagttgct agtttcaata aatggaaaac agattttgac
     9781 agaacagtta aaaagggttc aaaagctctg aaaatctggg ttccgtatca agtgaaaact
     9841 aagatttttg ctaatcaaaa tgagttgagt ttttctccat ctgagaatga aacggaagag
     9901 aaggaagtca cagttactcg attcaagtta gggaatgtct ttgatgtatc tcaaacagaa
     9961 ggaaaagaat tgccaaaagc aattaatgaa ttgactggag atgttaaaga ttatgaagat
    10021 ttgtaccgag cagccaaagc tgtttcaatg gataatcagg ttcctatcag ttttgaagaa
    10081 attaaaagag agagcacaaa tggttattac tctccagatg aaaatcgaat tgttatttca
    10141 aaaggcttaa agggtcaaga acagatttta aaaaccattt ttcatgaaat ggctcatgca
    10201 gatttacata gaggaagcaa tgcccaatat ggggacgacc aatatcgtaa gcaagaatta
    10261 caagctgaaa gtgtcgctta tgtcgtggct aatcattttg gttttgatac gagtagctac
    10321 agttttggct atttggctat ttgggcaaaa gataaaaatg gttttgaaga tatggtagaa
    10381 caactgcagg ttgttcagaa ggaagcaaaa agtttgattg atcggatgga tgctaagtta
    10441 gaattagtga aaaataaaac tgtgacgaaa gataagtttg ctgataaact ccaacaggca
    10501 aaagaaaaat ctgagcagtt ggggaatcaa aaggcggagg ctgtaaagca ggtggaagaa
    10561 aaaaagtccc tgagcaaccc tcgataatgg aggcattagt ccgtaggaag aaaaacaaaa
    10621 aaggagaaac ggaagatgat tgaacatcta aaacaagaaa cttttgatct tttaatggag
    10681 atattttttg aggatgaggc tacagattcg ccaaaagtga atgaagtcaa tcagcacatt
    10741 tcacgtaagg aatgtcttta cattcttcgt agagatatgc gaattaaaac aaactatgag
    10801 ctagaagaag tagaaatgta tcccattgta cttaaagaaa ttgaagggat gagtgatgaa
    10861 cgatttgaac aactaagaga cgaaattctt aaaatggaga tggttgatac aatggagctt
    10921 atactggaag acttaaaagt ttagtcaaac ttttccctcg tgataggata acattcctgc
    10981 ttgcagggat taggggattg gggatttccc caaagattta aaaaggtcaa agttagtcag
    11041 ggatgacacc ctgactaact ttgacctttt taaaaacagc atttggatat ccaagtgcta
    11101 atcttgccag aagaaaaggg ggcggacccc ctcagtcaaa aaatagcaga atagaggtgt
    11161 aaggttttgg aaaatggaga aaaacgcaaa agaccagttc aaaaattaat cagattaact
    11221 gaggaagaaa atcggttcat ttcaacaaag gttgcagaat ctggaatgac aaattttaat
    11281 gcttttgccc gaattatgtt gattatgggc gaggtcaaaa ttttaaattt tgaagaattg
    11341 agagaattgc gtaaggaaat aaatcggata ggcgtcaata ttaatcaggt cgcaaaaaag
    11401 gtaaacgaag atgaccaggc tagcctaact gaactgagtc agattcttga attgcagaaa
    11461 tatttgaaag atacagttag ccaatttatc caaaaacagg aaaatcaaac aaaggaacaa
    11521 gagcgatggt tgtaacaaag gttcttcaaa taaagggtgt agcttcttta ggacgatcta
    11581 caaaatatat tgaggatgaa gctaagacgg tcgagctgac tgatacgaaa agtttaaata
    11641 atgctttacg ctatatcgag aatccatcta aaacgagttt tttagaacaa gatgaacagt
    11701 ttgaatttcc agcagtggtt aaagatggcc gagtagtcaa gcaactggta tctacttatg
    11761 gaattacaga cgctagcaca gcgacagaag aatttctttt gaccaaaaag aatgctgctc
    11821 agcgagcagg gacaaaagaa cgatctgaca ttcacaatcc gaatcgggtt ttggctcacc
    11881 acatcatcca atcattttct cctgaagatg attggactcc acaagaaatt catgagattg
    11941 gtcgaaaaac aattttagaa ttaactggtg gacaacatga atttgtcata gcgactcaca
    12001 tggataaggg gcacattcac aatcacatca ttttcaattc cactaattct gttacattaa
    12061 aaaagtttcg ttggcagaaa aatactgcta gaagcttatt taatatttca aacaagtatt
    12121 ctgatttggc tggagctaaa attctcaagg agagattatg gactaatcga aaaacctatc
    12181 atgcctatcg caaaaaaaat tcttttcgct atgaaattaa atcacgctta gattttcttt
    12241 tgaaacattc aacctcttta gaggatttta agattaaggc acgagcttta aatcttgaag
    12301 ttgatacttc agggaaggaa ataaaatatc tcctgactga tcgggatcaa acaagaaatg
    12361 tgagggatcg tacactgtcc aaaaaaggaa attattcttt agagaaaatt tctgagaaag
    12421 tggttgctaa cgaagtaacc ttatctgttg atgaaataaa atctgaatat gaaaagatgg
    12481 tggcagaacg agaagatgat tttgaaatga gaatcacagt tgaagaatgg caggtgatgg
    12541 aagaaacgaa aaatggaatc tatcttgaaa tggaatttgg gcttagaaat aagggaacca
    12601 ttcttattcc agctcaccag attgaaagag cagaagatgg ctcttatgaa atttttatca
    12661 gaaaaaatga cttctactat tttgttaatc ctgaacatgc tgataagaat cgttatatga
    12721 agggagaaac agtcgcttcc cagttatcgt atgataatgg agaaatgatt atccgaaaaa
    12781 atcctaaaat ctcaactttg gatcagcttg ttcgtgaata taactatcta tccgctcatg
    12841 gagtgacaga aggacagcaa tttgatgaat tgctaaatcg ttttgaagag gaactagaag
    12901 aagtagataa cttacttgat aaactagatc aacgcttggg tgagcttaat aaaattcagt
    12961 ctgcatttct tgcattggaa tcaagtgatc ctcaggaagt gaaactagct attgctatta
    13021 tgaaagactt gagagtagat cctagcactc gcaaatctga gattgataaa cttgttaaag
    13081 aggcaacctt tgagcgccag actttgtatc aacgggtaga agcaattaca aaagattata
    13141 agctacatca agacattgag aaaaatgtgg agcagcgtaa ggagatagaa acttcattgt
    13201 aaaaaataag tataaatata tttacaaata taattataat ggtataatag aagtatagaa
    13261 aaggatggag aaatagaatg aagattatca catttgctgc tattaaaggc ggtgttggaa
    13321 aaacaacttt gacatttaat tatggagaat ggttggctag gaaagggcat aacgttctct
    13381 ttatagattt agaccatcaa tgtaatttga ctcaatgcta caatatttac gaaagtcaga
    13441 atacaattgc gaatgctttc aaaggaggcg atgtggatat taagcacatc aaggaaaata
    13501 tcagtctaat accaggttcg gttcagttgg atacagtgga gcgagattta gagaacagcg
    13561 ataagaaaaa tatgctcctt tatctttggt tagaagataa ctacgaaaag aagaagttgg
    13621 gtcagtttga ctatatcttg attgattgta gaccagactt tgcgacagct acaaaaaatg
    13681 ctgttgcggt tagtcacgct attattagtc ccttgactcc ttcagagttt ggttataatg
    13741 ctaaattcaa tctatcaact cggttagaag cgttcagaaa ggatgtaatc gattatcgta
    13801 ccagagagtc ctacattact gctgagttat attttctagc aaatatgatt cgaccaaact
    13861 atggatcatc aagagaatta ttggaagccc ttggacttga agccaaagaa aagggaacag
    13921 acaaccttct agggattgta ccagcaaaag agttattcaa tcattctacg attgataagg
    13981 tctctattgc agatatgaag gagaagcctg atctctatca aaaacataaa aagtttttta
    14041 tggagctaga ggagactttt tcaagaattt atgatacaat ataattatat ttgtaaacac
    14101 aaatacaatt ataaatataa ttagaaggag attatgatgg catttacacc gaaagaaaaa
    14161 gaaatttcac agattattga agcaactcat caacctgaac agcttccaga tatagatagt
    14221 tttgaaagtt ttgaacgtaa gaagcaattc cagtttactt tgaagccaag taatcggaaa
    14281 aagttagatc aagttgcaaa agcagctggt gcaaagtctg catcagatta tcttgataaa
    14341 ttaatcgaga aactatagtt atggatatat ttataactat aaacatatcc ataactacaa
    14401 ctgcttacta caaggagaaa taatggattt aattacaagg ctcttagcag agagagaagg
    14461 aaaagtacac ggtggtattt atgatattac acagaaacgc tttgcttata attctaaccg
    14521 aattgaagga agtcgtctga cagaagagca gactagctta atttatgaga caaagacaat
    14581 cgcaaatatt gatgcaaaag gaatcaaaat tgatgatttg gtagaaatga ataatcattt
    14641 taaatgtttt gattatatct tagataccgt taacgagcca ctgacagagg accatattaa
    14701 aacactgcat cgtgttctaa aaagtggaac aagttctgag cataacccga tagctccagt
    14761 tggtcgttat aaagtattgc aaaatgaggt aggaaaaatt gcgacagctt ctgttgaaca
    14821 gactgaagat gagatgcttt ctttactgat tggctatgat ttgaaaaaac aaaaagattt
    14881 gaattactta acaagctttc atgcacaatt tgaaaggatt catcctttcg cagatggtaa
    14941 tggtcgaata ggacgattgc ttttgtataa acaatgctta aaagaagggc ttaccccctt
    15001 tattgtggat gatattaata aggcgactta ttattcagcg cttgaagcct ttcaggttca
    15061 tgataacaga cagctattat ttgattattt ccaatctgag caactttttt atatgaatta
    15121 tcttaaaaat aaaggatttg aaggagctat caatgatgag aaagagggag acttcataaa
    15181 aaagtcagat aaattctaag aaaaggtgca acagtttaag ctaagaggag aaagtcatca
    15241 cttaaaaaag ttattataat tatatttaca aatataaaca taattataaa gtctgttgtt
    15301 ttttgttgta aaataccttc tattggttgc gagataataa tcttgacaac cgtactgagc
    15361 ctggttctta tatcaggctt ttattttacc ttgaaataga aacagttgaa cttctgatac
    15421 tcaactaaat cactttagta tctttcaata ataaataggg cgttgatttt aatttaaaga
    15481 aacagcctaa tttattcttg gaacaaaaat aaatttgatg acttgtttta aaaatcatac
    15541 aattttcata agaattgaaa gggaaatgaa aaattgtatg aaacaatttg atgaattgag
    15601 atttagtagc caggaacaag aaaagacaaa acaacatttt ttacagcata ttgaacagta
    15661 tgatgagtcg ataagctcca gtatgagatc aaaaggctat cgttgtaaaa atcaagctga
    15721 acgtaccgta gcttttacat ttggagaagt gaccttttct agaaaacgtt ggtataagaa
    15781 tggtgaatgt agaataccag ttgatgaaat gttaggatta gaaaagaatg tacgtcattc
    15841 acaggaacta ttgtatcaag ctgcggttct agctacaaaa ctaccctatc gtcaggtagg
    15901 agagacaatt gagatggttt ataatgtaac tgtcactaaa gataccgtca ataaggttgt
    15961 taaattagcc aatcaattac tagaagaaaa ggatgattat cgatttttta aagaagagaa
    16021 gaagattgaa aaattaaagc agatatcatc tacatagagg gagatggtgt atatgtgaaa
    16081 acatctgaag atggttctga aaaaaagaat atggatttat cacattttgt agttcataca
    16141 ggttctaaac agattggccc aaatcgtttt gagctagaaa ataaaaaaga gcttatccga
    16201 ttggataagc gctcagctcg tagagaattg ttggatttat tggaaaatga atatgaaatt
    16261 acaaatggga caatactagt tactaattct gactgtggca agggttatac accacatgta
    16321 tttactgaaa tcgctaaatc atttaatgtt aagaggcatg agcatttttg ggacgaatat
    16381 cacttgaata aagaaattaa agaatttaca aagtcttatc cgagagaatt gagagaagac
    16441 ttatttcaag ctattaaaga gcatgataag aaattattaa ggcgtacact agatactata
    16501 gaatcattgg ttagtagtga agagggagag gaaaaatttg aatattattc gagtaggtta
    16561 atgaggaatt ttcagtatac gaaaccagcg gaaatgaggg gacttccaaa ggcaggtatt
    16621 gggattatgg agagccagca tagaaaaata acgtatagaa tgaagcatag agggatgtat
    16681 tggacaagtg aaggtgggat agccgtagcg aatatgatat tgttagagcg tgaaggaaaa
    16741 ttaagagatt tattttttgg agaatggaag gaggactatg atgagtatac gtcattggat
    16801 catatcagtg cggatagtgt tcgacctaaa aatgactcta aagactacaa acttccccgt
    16861 ttacataaaa atatagaaaa gatatttaag atgaaataat ttaagtgcta atttcaacga
    16921 aaacacaaat ataaataagc aaaaatttct agtgagattt gggctttttt ggcgtggaat
    16981 aattgacatt tatcctgatt ttggtataat agagatataa aaaacaacga aaaaaggagt
    17041 tggaaatgag cctccaactc cgcagagtaa cacaacccaa acttgtatta ctcaatcaac
    17101 taaaatgata gcataagaaa aaatcattgt caagggctga gcatacaaaa atgtttagcc
    17161 ctttcgtgta tttgcattta tttatatgga aatctgggat ttctcaaaaa tcacgacaca
    17221 tacaaaataa ctttttatct tgacaagagc tagaaaactt ggtatcatat aaaagttgag
    17281 aaaagcagaa gtgagagctt ctcgccttgt gacattaagt tgcctggccc tacggatgaa
    17341 aagtttctaa gaaacgctat cataacgtgc gggcttgtat atttacaagt ccgctattgt
    17401 ttttctctaa taaaacaaaa gaggtgaaaa ccatagcaaa gcaagactta ttcatcaatg
    17461 atgagattcg tgtacgtgaa gttcgcttga ttggtcttga aggagaacag ctaggtatca
    17521 agccactcag tgaagcgcaa gctttggctg ataacgctaa tgttgaccta gtattgattc
    17581 aaccccaagc caaaccgcct gttgcaaaaa ttatggacta cggtaagttc aaatttgagt
    17641 accagaagaa gcaaaaagaa caacgtaaaa aacaaagcgt tgttactgtg aaagaagttc
    17701 gtctaagtcc aacaattgac aagggtgact ttgatacaaa acttcgtaat gcacgtaagt
    17761 tccttgaaaa aggaaataaa gttaaggtat ctattcgctt taagggtcgt atgattaccc
    17821 ataaagagat tggtgcaaaa gttttagccg agtttgctga agcaactcaa gatattgcca
    17881 tcatcgaaca acgtgctaaa atggatggac gtcaaatgtt catgcaattg gcgccagcga
    17941 ctgacaaaaa ataattgtca gaaagttaaa taaaggagaa aaaatcatgc caaaacaaaa
    18001 aacacaccgc gcatcagcta aacgtttcaa acgtacaggt tctggtggac ttaaacgttt
    18061 ccgtgcttac acttctcacc gtttccacgg aaaaactaag aaacaacgtc gtcatcttcg
    18121 taaagcatct atggtgcatt caggagatta caaacgtatc aaagcaatgc ttactcgctt
    18181 gaaataatag cttgactgta agtaaacaat tctaggaaat atttggagga aataaaacat
    18241 ggcacgtgtt aaaggtggcg ttgtatcacg caaacgtcgt aaacgtattc ttaaattagc
    18301 aaaaggttac tatggagcta aacacatctt gttccgtact gcaaaagaac aagtaatgaa
    18361 ctcttactac tatgcatacc gtgaccgtcg tcagaaaaaa cgtgacttcc gcaaattgtg
    18421 gatcactcgt atcaatgcgg cagctcgtat gaacggactt tcatactcac aattgatgca
    18481 tggtttgaaa ttggctgaga tcgaagttaa ccgtaaaatg cttgctgact tggctgttaa
    18541 cgatgcagta gctttcacag ctcttgcaga tgcagctaaa gcaaaacttg gtaaataaca
    18601 actgatgaga ctggaacagg attgtccagt ctttttaaaa ataaaggaga aagatatggc
    18661 ttcaaaaatg ctacacactt gcttacgagt agaaaatctt gaaaaatcaa tcgcatttta
    18721 tcaagatgct tttggtttta aagaattgcg tcgcagagat tttccagacc atgccttcac
    18781 gattgtctat ctaggtcttg agggtgatga ctatgagttg gagttgactt ataactacga
    18841 tcacggtccg tatgtggttg gtgatgggtt tgcccatatc gccctcagta cacctgatct
    18901 tgagtcactt catcaagagc acagtgcaaa aggctatgaa gtgactgagc caaatggtct
    18961 accaggaact acaccaaact attactttgt caaagaccct gatggataca aggtcgaagt
    19021 cattcgtgaa aaataatttc gtgcaagtta agtagaatat tcgttttcta cttgactttt
    19081 tttagctgaa agagtatact aataaaaatt caacctttaa ggggagtcca gagagactca
    19141 caaggtgtca gataaaagaa tagtgcaatt ttctagagga gactttttga atgtgctctc
    19201 ttgtgttgta cgattttaac tgaggccttg cactagcaag gtcttttctt tatctggtcc
    19261 ccttaaaatt taaggaggaa aagttatgaa tcccacatgt aagaagcgtt tgggtgtcat
    19321 tcggttggaa accatgaagg tggttgcaca agaggaaatc gcgccagcaa tctttgaatt
    19381 agtcctagaa ggagaaatgg ttgaagccat gcgagcaggc caatttcttc atctgcgtgt
    19441 accggacgat gcccatctct tacgtcgtcc tatttcaatt tcgtctattg acaaggtaaa
    19501 caagcagtgt cacctcattt atcggattga gggagctggg actgcaattt tttcaacctt
    19561 aagtcaggga gacactcttg atgtgatggg gcctcaggga aatggttttg acttgtctga
    19621 ccttgatgag cagaatcagg ttctccttgt tggtggtggg attggtgttc cacccttgct
    19681 tgaggtggcc aaggaattgc atggacgtgg agtgaaagta gtgacagtcc tcggttttgc
    19741 taataaggat gctgttattt tgaaaacgga attggctcag tatggtcagg tctttgtaac
    19801 gacagatgat ggttcttatg gcatcaaggg aaatgtttcc gttgttatca atgatttaga
    19861 tagtcagttt gatgctgttt actcgtgtgg ggctccagga atgatgaagt atatcaatca
    19921 aacctttgat gatcacccaa gagcctatct atctctggaa tctcgtatgg cttgtgggat
    19981 gggagcttgc tatgcctgtg ttctaaaagt accagaaagc gagacggtca gccaacgcgt
    20041 ctgtgaagat ggtcctgttt tccgcacagg aacagttgta ttataaggag aaaattatga
    20101 ctacaaatcg attacaagtg tctctacctg gtttggattt gaaaaatccg attattccag
    20161 catcaggctg ttttggcttt ggacaagagt atgccaagta ctatgattta gaccttttag
    20221 gttctattat gatcaaggcg acaacccttg aaccacgttt tgggaatcca actccaagag
    20281 tggcagagac gcctgctggt atgctcaatg caattggctt gcaaaatcct ggtttagagg
    20341 ttgttttggc tgaaaagcta ccttggctgg aaagagaata tccaaatctt cctattattg
    20401 ccaatgtagc tggtttttca aaacaagagt atgcagctgt ttctcatggg atttccaagg
    20461 caactaatgt aaaagctatc gagctcaata tttcttgtcc caatgttgac cactgtaatc
    20521 atggactttt gattggtcaa gatccagatt tggcttatga tgtggtgaaa gcagctgtgg
    20581 aagcctcaga agtgccagtt tatgtcaaat taaccccgag tgtgaccgat atcgttactg
    20641 tcgcaaaagc tgcagaagat gcgggagcaa gtggcttgac catgatcaat actctggttg
    20701 gaatgcgctt tgacctcaaa accagaaaaa caatcttggc taatggaaca ggtggaatgt
    20761 caggtccagc agtctttcca gtagccctca aactcatccg ccaagtagcc caaacaacag
    20821 acctgcctat cattggaatg gggggagtgg attcggctga agctgcccta gaaatgtatc
    20881 tggctggggc atctgctatc ggagttggaa cagctaactt taccaatcct tatgcctgcc
    20941 ctgacatcat cgaaaatttc ccaaaagtca tggataaata cggtattagc agtctggaag
    21001 aactccgtca ggaagtaaaa gagtctctga ggtaaactgc aatcaatctg ttcttgattt
    21061 tttattagtt tgtaatatga atttaggaga attttggtac aataaaataa ataagaacag
    21121 aggaagaagg ttaatgaaga aagtaagatt tattttttta gctctgctat ttttcttagc
    21181 tagtccagag ggtgcaatgg ctagtgatgg tacttggcaa ggaaaacagt atctgaaaga
    21241 agatggcagt caagcagccg atgagtgggt ttttgatact cattatcaat cttggttcta
    21301 tataaaagca gatgctaact atgctgaaaa tgaatggata aagcaaggtg acgactattt
    21361 ttacctcaaa tctggtggct atatgaccaa atcagaatgg gtagaagaca agggagcctt
    21421 ttattatctt gaccaagatg gaaagatgaa aagaaatgct tgggtaggaa gttcctatgt
    21481 tggtgcaaca ggtgccaaag taatagaaga ctgggtctat gattctcaat acgatgcttg
    21541 gttttatatc aaagcagatg gacagcacgc agagaaagaa tggctccaaa ttaaagggaa
    21601 ggactattat ttcaaatccg gtggttatct actgacaagt cagtggatta atcaagctta
    21661 tgtgaatgct agtggtgcca aagtacagca aggttggctt tttgacagac aataccaatc
    21721 ttggttttac atcaaagaaa atggaaacca tgctgataaa gaatggattt tcgagaatgg
    21781 tcactattat tatctaaaat ccggtggcta catggcagtc aatgaatgga tttgggataa
    21841 ggaatcttgg ttttatctca aatctgatgg gaaaatagct gaaaaagaat gggtctacga
    21901 ttctcatagt caagcttggt actacttcaa atccggtggt tacatgacag ccaatgaatg
    21961 gatttgggat aaggaatctt ggttttacct caagtctgat ggcaaaatgg ctgaaaaaga
    22021 atgggtctac gattctcata gtcaagcctg gtactacttc aaatctggtg gctacatgac
    22081 agccaatgaa tggatttggg ataaggaatc ttggttttat ctcaaatctg atgggaaaat
    22141 agctgaaaaa gaatgggtct acgattctca tagtcaagcc tggtactact tcaaatctgg
    22201 tggctacatg gcgaaaaatg agacagtaga tggttatcag cttggaagcg atggtaaatg
    22261 gcttggagga aaagctacaa atgaaaatgc tgcttactat caagtagtgc ctgttacagc
    22321 caatgtttat gattcagatg gtgaaaagct ttcctatata tcgcaaggta gtgtcgtatg
    22381 gctagataag gatagaaaaa gtgatgacaa gcgcttggct attactattt ctggtttgtc
    22441 aggctatatg aaaacagaag atttacaagc gctagatgct agtaaggact ttatccctta
    22501 ttatgagagt gatggccacc gtttttatca ctatgtggct cagaatgcta gtatcccagt
    22561 agcttctcat ctttctgata tggaagtagg caagaaatat tattcggcag atggcctgca
    22621 ttttgatggt tttaagcttg agaatccctt ccttttcaaa gatttaacag aggctacaaa
    22681 ctacagtgct gaagaattgg ataaggtatt tagtttgcta aacattaata atagcctttt
    22741 ggagaacaag ggcgctactt ttaaggaagc cgaagaacat taccatatca atgctcttta
    22801 tctccttgcc catagtgccc tagaaagtaa ctggggaaga agtaaaattg ccaaagataa
    22861 gaataatttc tttggcatta cagcctatga tacgacccct tacctttctg ctaagacatt
    22921 tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg attaaggaaa attatatcga
    22981 taggggaaga actttccttg gaaacaaggc ttctggtatg aatgtggaat atgcttcaga
    23041 cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa atcaatgaga agctaggtgg
    23101 caaaaattag tactataagt gaatatgatt tgagtgaata gtaagttaaa aatcctgatt
    23161 tcaagtaaaa tcaggatttt ttcatggatg caattttttt ggagtctggt gtgacgcgga
    23221 gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc accagttggt ttattgagtt
    23281 ttttgacttc aatcatatct acctgcacca gattcgacag gcgcccttga gagaagtagg
    23341 cagctaactc tgctgcgtct gtctttactg catcagatgg gtcaagattt cctgagatga
    23401 caacatggct tccaggaatg tccttagcat ggaaccaaag ttcctccttg cgggccattt
    23461 taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac atagatgatg gttttgccat
    23521 cgcttgctag atattgttct agttttttgc gtttctggat tttctcccgt tgtcttctgc
    23581 ggataaaacc tgtttgaatc aattcttcac ggatttcagc gatttcttcc agtccagctt
    23641 ggttgaggac ggtttctaca ctttccagat agagaatagt ggctttggtt tcttcaatca
    23701 aatcagtcaa gtatttgaca gcttctttga gtttctgata ccgtttaaaa tagcgttggg
    23761 cattctggtt gggagtcaga gccttatcaa gcgcaatcat gataggttgg ttggtatagt
    23821 agttgtctag gataacctga tcttggtcgt taggcactcg gtggaggaag gttgtcagta
    23881 attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc cagtaactct ttttcctgtt
    23941 ttttgagttt gtgtcggttt ttctgaagtt cattttcaac acgacgaatc agttcactgg
    24001 cctgctgttt gacgcggtcg cgctcagcct tatccttata gtaggtgtcc aacaaatcag
    24061 aaagatttgc aaaaggctct cccacctgat ttgcaaaagg aactggactg aaggaagtct
    24121 cagtcaagca tggcttggtt tcttgattga aaaaatttcg gaaagcggaa agtttttcac
    24181 taaccagtat cctttccaat tcatttgccg tatcgcgtcc cagaccttga aagaggcttt
    24241 gaagattttt tgctgttagt tcttgggttt gcaggatttc aaagagcttt tcatccttga
    24301 tagtaaaagg attgagagat tctgtacttg gcggagcgat ataggtcgat cctggaagta
    24361 aggtgcggta gctattttgt gaaaagccga cgtgtttgat aacttcgagg attttatgac
    24421 tgcttttatc gaccagtaga atattactgt gtttcctcat aatttcgata atcaaggtag
    24481 cctggatatg gtctccaatc tcgtttttat tggaaactgt aatttccaca atacggtcat
    24541 tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa atactttctc aaaatcatga
    24601 taaaggtaga aggttgggct ggattttcaa aagtcgtttg ggtcagctga atgcgtccaa
    24661 aaactggatg ggcagaaagg agcaggcgat ggctttggcg attgctgcgg atttgcaaga
    24721 ccaactcttg ttcaaaaggc tgattgattt tctggatgcg accattcact aattcgcttc
    24781 gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa tgacatcgtt ctctccttgt
    24841 gattgtattc catagtatta tatcaaaaag gtagaataaa atcatggaaa tgtggtataa
    24901 taaagccaag taaagagaaa cgagaagcac atgtatattg aaatggtaga tgaaactggt
    24961 caagtttcaa aagaaatgtt gcaacaaacc caagaaattt tggaatttgc agcccaaaaa
    25021 ttaggaaaag aagacaagga gatggcagtc acttttgtga ccaatgagcg tagtcatgaa
    25081 cttaatctgg agtaccgtga caccgaccgt ccgacagatg tcatcagcct tgagtataaa
    25141 ccagaattgg aaattgcctt tgacgaagag gatttgcttg aaaatccaga attggcagag
    25201 atgatgtttg agtttgatgc ctatattggg gaattgttca tctctatcga taaggctcat
    25261 gagcaggccg aagaatatgg tcacagcttt gagcgtgaga tgggcttctt ggcagtacac
    25321 ggctttttac atattaacgg ctatgatcac tacactccgg aagaagaagc ggagatgttc
    25381 ggtttacaag aagaaatttt gacagcctat ggactcacaa gacaataaac gaaaatggaa
    25441 aaatcgtgac ttgatatcca gtttagaatt tgctttgaca ggtattttta ctgctatcaa
    25501 ggaagaacgc aatatgcgaa aacacgcagt gacggctcta gtggtcatcc ttgcaggttt
    25561 tgtttttcag gtgtcacgaa tcgaatggct ctttctccta ttgagcattt tcttggtagt
    25621 agcctttgag attatcaact ctgctattga aaatgtggtg gatttggcca gtcactatca
    25681 cttttccatg ctggctaaaa atgccaagga tatggcggct ggcgcggtat tagtggtttc
    25741 tcttttcgca gccttaacag gcgcattgat ttttctccca cgaatctggg atttattatt
    25801 ttaaacagta agaggaaatt atgactttta aatcaggctt tgtagccatt ttaggacgtc
    25861 ccaatgttgg gaagtcaacc tttttaaatc acgttatggg gcaaaagatt gccatcatga
    25921 gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat ttacacgact gataaggagc
    25981 aaattgtctt tatcgacaca ccagggattc acaagcctaa aacagctctc ggagatttca
    26041 tggttgagtc tgcctacagt acccttcgcg aagtggacac cgttcttttc atggtgcctg
    26101 ctgatgaagc gcgtggtaag ggggacgata tgattatcga gcgtctcaag gctaccaagg
    26161 ttcctgtgat tttggtggtg aataaaatcg ataaggtcca tccagaccag ctcttgtctc
    26221 agattgatga cttccgtaat caaatagact ttaaggaaat tgttccaatc tcagcccttc
    26281 agggaaataa tatgtctcgt ctagtggata ttttgagtga aaatctggat gaaggtttcc
    26341 aatatttccc gtctgatcaa atcacagatc atccagaacg tttcttagtt tcagaaatgg
    26401 ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc gcattctgta gcagtagttg
    26461 ttgactgtat gaaacgagac gaagagacag acaaggttca catccgtgca accatcatgg
    26521 tcgagcgcga tagccaaaaa gggattatca tcggtaaagg tggcgctatg cttaagaaaa
    26581 tcggtagtat ggcccgtcgt gatatcgaac tcatgctagg agacaaggtc ttcctagaaa
    26641 cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct agatttggct gactttggct
    26701 ataatgaaaa agaatactaa gtagaggtgg gctcatgcct gcttcttgtt tttacagaag
    26761 gaggacttat gcctgaatta cctgaggttg aaaccgtttg tcgtggctta gaaaaattga
    26821 ttataggaaa gaagatttcg agtatagaaa ttcgctaccc caagatgatt aagacggatt
    26881 tggaagagtt tcaaagggaa ttgactagtc agattatcga gtcaatggga cgtcgtggaa
    26941 aatatttgct tttttatctg acagacaagg tcttgatttc ccatttgcgg atggagggca
    27001 agtattttta ctatccagac caaggacctg aacgcaagca tgcccatgtt ttctttcatt
    27061 ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa gtttggaacc atggaactct
    27121 tggtgcctga ccttttagac gcctacttta tttctaaaaa attaggtcct gaaccaagcg
    27181 aacaagactt tgatttacag gtctttcaat ctgcccttgc caagtccaaa aagcctatca
    27241 aatcccatct cctcgaccag accttggtag ctggacttgg caatatctat gtggatgagg
    27301 ttctctggcg agctcaggtt catccagcta gaccttccca gactttgaca gcagaagaag
    27361 cgacagctat tcatgaccaa accattgctg ttttgagcca ggctgttgaa aaaggcggtt
    27421 ccaccattcg gacctatacc aatgcctttg gggaagatgg aagcatgcag gactttcatc
    27481 aggtctatga caaggctggt caagcatgtt cacgctgtgg gacagtgatt gagaaattcc
    27541 agctcggtgg acgtggaacc cacttttgtc caaactgtca aaggagggac tgatgggaaa
    27601 aatcatcgga atcactgggg gaattgcctc tggtaagtca actgtgacaa attttctaag
    27661 aaagcaaggc tttcaagtag tggatgccga cgcagtcgtc caccaactac agaaacctgg
    27721 tggtcgtctg tttgaggctc tagtacagca ctttgggcaa gaaatcattc ttgaaaacgg
    27781 agaactcaat cgccctctcc tagctagtct catcttttca aatcctgaag agcaaaaatg
    27841 gtcgaagcaa attcaagggg agattatccg tgaggaactg gctactttga gagaacagtt
    27901 ggctcagaca gaagagattt tcttcatgga tattccccta ctttttgagc aagactacag
    27961 cgattggttt gctgagactt ggttggtcta tgtggaccga gatgcccaag tagaacgctt
    28021 aatgaaaagg gaccagttgt ccaaagatga agctgagtct cgtctggcag cccagtggcc
    28081 tttagaaaaa aagaaagatt tggccagcca ggttcttgat aataatggca atcagaacca
    28141 gcttcttaat caagtgcata tccttcttga gggaggtagg caagatgaca gagattaact
    28201 ggaaggataa tctgcgtatt gcctggtttg gtaattttct gacaggagcc agtatttctt
    28261 tggttgtatc ttttatgtcc atcttcgtgg aaaatctagg tgtagggagt cagcaagtcg
    28321 ctttttatgc aggcttagca atttctgtct ctgctatttc cgcggcgctc ttttctccta
    28381 tttggggtat tcttgctgac aaatacggcc gaaaacccat gatgattcgg gcaggtcttg
    28441 ctatgactat cactatggga ggcttggcct ttgtcccaaa tatctattgg ttaatctttc
    28501 ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa tgaaacggca ctgatagcca
    28561 gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac tttgtctaca ggcgtagttg
    28621 caggtactct aactggtccc tttattggtg gctttatcgc agaattattt ggcattcgta
    28681 cagttttctt actggttggt agttttctat ttttagctgc tattttgact atttgcttta
    28741 tcaaggaaga ttttcaacca gtagccaagg aaaaggctat tccaacaaag gaattattta
    28801 cctcggttaa atatccctat cttttgctca atctcttttt aaccagtttt gtcatccaat
    28861 tttcagctca atcgatcggc cctattttgg ctctttatgt acgcgactta gggcagacag
    28921 agaatcttct ttttgtctct ggtttgattg tgtccagtat gggcttttcc agtatgatga
    28981 gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa tcatcgtctc ttggttgtcg
    29041 cccagtttta ttcagtcatc atctatctcc tctgtgccaa tgcctctagc ccccttcaac
    29101 taggactcta tcgtttcctc tttggcttgg gaaccggtgc cttgattccc ggggttaatg
    29161 ccctactcag caaaatgact cccaaagccg gcatttcgag ggtctttgcc ttcaatcagg
    29221 tattctttta tctgggaggt gttgttggtc ccatggcagg ttctgcagta gcaggtcaat
    29281 ttggctacca tgctgtcttt tatgcgacga gcctttgtgt tgcctttagt tgtctcttta
    29341 acctgattca atttcgaaca ttattaaaag taaaggaaat ctagtgcgag taaaaatcaa
    29401 tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc agtaaaaatt caaaaaccca
    29461 tccagacaag attgaggttt taaagtattg tcccaaggaa agaaaagtaa ccctacatct
    29521 tgaatctaag tagattttat g
//
LOCUS       DAVFJR010000026        29344 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVFJR010000026 DAVFJR010000000
VERSION     DAVFJR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.027"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..433)
                     /locus_tag="VU722_001394"
     CDS             complement(<1..433)
                     /locus_tag="VU722_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772353.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQRPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFE"
     gene            627..1124
                     /locus_tag="VU722_001395"
     CDS             627..1124
                     /locus_tag="VU722_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU1772354.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            1124..2779
                     /gene="dnaX"
                     /locus_tag="VU722_001396"
     CDS             1124..2779
                     /gene="dnaX"
                     /locus_tag="VU722_001396"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU1772355.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2807..3001
                     /locus_tag="VU722_001397"
     CDS             2807..3001
                     /locus_tag="VU722_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU1772356.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            3151..3921
                     /gene="sufC"
                     /locus_tag="VU722_001398"
     CDS             3151..3921
                     /gene="sufC"
                     /locus_tag="VU722_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU1772357.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDMVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3949..5211
                     /gene="sufD"
                     /locus_tag="VU722_001399"
     CDS             3949..5211
                     /gene="sufD"
                     /locus_tag="VU722_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU1772358.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIESLELPVIERVKFH
                     RWNLGDGTITESEPSANVPDFTALDNHLKLVQVGTQTVFEQIPVELAQQGVVFTDFHS
                     ALEEIPELIEELFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEIKEPIEGVFYQDS
                     DSDVPFNKHIMIIAGKNSKISYLERLESRGEGSTKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQIQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            5222..6448
                     /locus_tag="VU722_001400"
     CDS             5222..6448
                     /locus_tag="VU722_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1772359.1"
                     /translation="MLDVEVIRKDFPILDQIVNDEPLVYLDNAATTQKPLAVLETINR
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     YAEEVLTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMVDLRAKLTD
                     KVQFVSLAHASNVLGVVNPIKEITQMAHQVGAIMVVDGAQSTPHMKIDVQDLDVDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MVGAIGLAAAVDYLEKIGMDAIEAHEQELIAYVFPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLDVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6435..6875
                     /locus_tag="VU722_001401"
     CDS             6435..6875
                     /locus_tag="VU722_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU1772360.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFNAEDRLEDIAFLNSGCTISTASASMMTEAVLGKTKQEILELATIFSEMVQGQ
                     KDDRQDSLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6933..8345
                     /gene="sufB"
                     /locus_tag="VU722_001402"
     CDS             6933..8345
                     /gene="sufB"
                     /locus_tag="VU722_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU1772361.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEDVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDEVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFEKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANVGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSKVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8576..9817)
                     /locus_tag="VU722_001403"
     CDS             complement(8576..9817)
                     /locus_tag="VU722_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU1772362.1"
                     /translation="MKKIFLTLLTISLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLRDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLESMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVAHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9920..11029
                     /locus_tag="VU722_001404"
     CDS             9920..11029
                     /locus_tag="VU722_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU1772363.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVRVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11675..12022
                     /gene="ssrA"
                     /locus_tag="VU722_001405"
     tmRNA           11675..12022
                     /gene="ssrA"
                     /locus_tag="VU722_001405"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(12192..12279)
                     /locus_tag="VU722_001406"
     tRNA            complement(12192..12279)
                     /locus_tag="VU722_001406"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12243..12245),aa:Ser,seq:gga)
     gene            12441..13181
                     /locus_tag="VU722_001407"
     CDS             12441..13181
                     /locus_tag="VU722_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1772364.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQGIKEKTEVIEV"
     gene            13178..14089
                     /gene="pfkB"
                     /locus_tag="VU722_001408"
     CDS             13178..14089
                     /gene="pfkB"
                     /locus_tag="VU722_001408"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU1772365.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            14086..16038
                     /locus_tag="VU722_001409"
     CDS             14086..16038
                     /locus_tag="VU722_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1772366.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            16202..18427
                     /locus_tag="VU722_001410"
     CDS             16202..18427
                     /locus_tag="VU722_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU1772367.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18471..18899)
                     /locus_tag="VU722_001411"
     CDS             complement(18471..18899)
                     /locus_tag="VU722_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772368.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITATITIMN
                     ALDNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVKE
                     EKKEEQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            19037..20179
                     /locus_tag="VU722_001412"
     CDS             19037..20179
                     /locus_tag="VU722_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1772369.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHLAVK
                     ESALWLKSQGFEVDFAPVDKKGFVDVEALADLIRPDTTLVSIVAVNNEIGSVQPIEAI
                     SELLADQPTISFHVDAVQALAKIPTEKYLTERVDCATFSGHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFIFSAEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            20188..21402
                     /gene="thiI"
                     /locus_tag="VU722_001413"
     CDS             20188..21402
                     /gene="thiI"
                     /locus_tag="VU722_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU1772370.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVR
                     ADRDRAHAHLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21538..22362
                     /locus_tag="VU722_001414"
     CDS             21538..22362
                     /locus_tag="VU722_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1772371.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGHSWKIIPAIKRNSDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     KSPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            22384..23124
                     /locus_tag="VU722_001415"
     CDS             22384..23124
                     /locus_tag="VU722_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU1772372.1"
                     /translation="MHIEYLSHWSGHLNREMYLNRYGHAGIPVVVFASSGGSHNEYYD
                     FGMIDACTSFIEEGRVQFFTLSSVDGESWLATWKNAHDQAEMHRSYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDKKQIPAW
                     FAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            23137..24303
                     /locus_tag="VU722_001416"
                     /pseudo
     CDS             23137..24303
                     /locus_tag="VU722_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
     gene            24811..25776
                     /locus_tag="VU722_001417"
     CDS             24811..25776
                     /locus_tag="VU722_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU1772373.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDTV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLTNPPFKGSLDYNSTYNDLLATVKTKKQNYSFFLFSCEL"
     gene            25764..26303
                     /locus_tag="VU722_001418"
                     /pseudo
     CDS             25764..26303
                     /locus_tag="VU722_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819381.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            26316..26901
                     /locus_tag="VU722_001419"
                     /pseudo
     CDS             26316..26901
                     /locus_tag="VU722_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            26961..27197
                     /locus_tag="VU722_001420"
     CDS             26961..27197
                     /locus_tag="VU722_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU1772374.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            27194..27607
                     /locus_tag="VU722_001421"
     CDS             27194..27607
                     /locus_tag="VU722_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU1772375.1"
                     /translation="MTIYLTEKQIEKINSLAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27725..28679
                     /locus_tag="VU722_001422"
                     /pseudo
     CDS             27725..28679
                     /locus_tag="VU722_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            28713..>29344
                     /locus_tag="VU722_001423"
     CDS             28713..>29344
                     /locus_tag="VU722_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1772376.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSE"
BASE COUNT         8876 a         5260 c         6413 g         8795 t
ORIGIN      
        1 actcaaagtg gaagtcattg agcttgcgaa tgacagttga agttgaaatg gccagctgat
       61 gagcaatatc agtcatagaa attttttcaa ttaacttttg agcaattttt tggttgatga
      121 tacgagggat ttggtgattt ttctttacca ggggagtctc agcaaccatc atttttgaac
      181 agtgatagca cttgaaacgg cgttttctaa ggagaattct agaaggcata ccagttgttt
      241 caagataagg aattttagaa ggtctttgaa agtcatattt cttcatttga cttccgcact
      301 cagggcaaga tggggcgtcg tagtccagtt tggcgatgat ttctttgtgt gtatctttat
      361 tgatgatatc tagaatcttg atgtttgggt ctttaatatc gagcagtttt gtgataaaat
      421 gtaattgttc catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat
      481 atgggacttt ttttctacac aaaaataggc tccataatat ccatagggaa tttacccact
      541 acaaatatta tagagcccaa aatcctttgt ttactaaaca agggattttt cttttgtctc
      601 tgctcctttt ttgatataat agttctatgt taaaatcaga aaaacaatca cgttatcaaa
      661 tgttaaatga agaattgtcc ttcctattgg aaggcgaaac caatgttttg gctaatcttt
      721 ccaacgccag tgctctcata aaatcacgtt ttcctaatac cgtatttgca ggcttttatt
      781 tgttcgatgg aaaggaattg gttttaggtc ccttccaagg aggtgtttcc tgcatccgta
      841 ttgcactagg caagggtgtt tgtggtgagg cagctcactt tcaggaaact gttattgttg
      901 gagatgtgac gacctatctc aactatattt cttgtgatag tctagctaaa agtgaaattg
      961 tggtgccgat gatgaagaat ggtcagttac ttggagttct ggatctggat tcttcagaga
     1021 ttgaggatta cgatgctatg gatcgagatt atttggaaca atttgtcgct attttgcttg
     1081 aaaagacagc atgggacttt acgatgtttg aggaaaaatc ttaatgtatc aagcacttta
     1141 tcgaaaatat agaagtcaaa acttctccca gttagttggt caagaagttg tggctaagac
     1201 tcttaaacaa gcggtggagc aagagaaaat aagtcacgct tatctttttt ctggtcctcg
     1261 tggaacggga aaaaccagtg ttgctaaaat ctttgccaag gctatgaact gtcccaatca
     1321 agtgggtggc gaaccttgca ataactgcta tatttgtcaa gcagtgacgg acggtagttt
     1381 agaagatgtc attgaaatgg atgcagcttc taataatggg gtagatgaaa ttcgcgaaat
     1441 tcgtgataaa tctacctatg cgcctagcct tgctcgttat aaggtttata tcatagatga
     1501 ggttcacatg ctgtctacag gggcttttaa tgccctccta aagacgctgg aagaaccaac
     1561 acagaatgta gtctttattt tggccactac tgaattgcac aagattcctg ctactattct
     1621 atcccgtgtg caacgttttg agtttaaatc aattaagaca caggatatta aggaacatat
     1681 tcactatatc ttagaaaaag aaaatatcag ttctgaacca gaggctgtgg aaatcattgc
     1741 cagacgggcg gaaggtggaa tgcgggacgc cttgtctatt ttggatcaag ccctgagttt
     1801 gacacaggga aatgagctga cgactgctat ctctgaagaa attactggca ccattagcct
     1861 atcagccttg gatgattatg tggcggcctt gtctcaacag gatgttccca aagctttgtc
     1921 ttgcttgaat cttctttttg acaatggtaa gagcatgact cgttttgtga ccgatctttt
     1981 gcactattta agagacttgt taattgttca aacaggggga gaaaatactc atcatagttc
     2041 agtctttgta gaaaatttgg cacttcctca aaaaaatctg tttgaaatga ttcgcttagc
     2101 aacagtgagt ttagcagata ttaagtctag tttgcagccc aagatttatg ctgaaatgat
     2161 gaccgtccgt ttggcggaaa tcaagccaga accagctcta tcaggagcgg ttgaaaatga
     2221 aattgctacg ctgagacagg aagttgcccg tctcaaacaa gagctttcta atgtaggtgc
     2281 ggttcctaaa caagttgcac cagctcctag tcgaccagct acgggcaaaa cagtctatcg
     2341 tgtcgatcgt aataaagtgc aatctatctt acaagaggcc gtcgaaaatc ctgatttagc
     2401 acgtcaaaat ctaattcgtt tgcagaatgc ctggggagag gtaattgaaa gtctaggtgg
     2461 gccggacaag gctctgctag ttggttctca accggttgct gccaatgaac accatgctat
     2521 tcttgctttt gagtctaact tcaatgctgg tcaaactatg aaacgagaca atctcaatac
     2581 catgtttggt aatatcctca gtcaggcggc aggtttttca cctgagattt tagctatttc
     2641 catggaggaa tggaaagaag ttcgcgcagc cttttcagcc aaagccaaat cttctcaaac
     2701 tgaaaaagaa gtagaagaaa gcctgattcc agaaggattt gaatttttgg ctgataaagt
     2761 gaaggtagag gaagactaaa gaaagatttc atgatacaat aagtttatga ataaacaaca
     2821 atttattatt atggcgctgt ttacagctgc tgagacctat tttttcaatg aagcctggat
     2881 gactggccgc tatattatgg cagccttttg ggcaatttta ctctttagaa atttccgagt
     2941 cagttatgtg atgggtaaaa tcgttgatgt catcgatcag cattttaata ggaaagacta
     3001 gccctcagct tccagacaaa atcaaagcct tttaggcttt tttttgttat actagaaaag
     3061 tatatttata gaatttttgc tctatttctg gggaaatcag acgtttttct agtaagtact
     3121 gtaaaagttt tgaaaaagaa aggaactatt atgtcagtaa tagagatcaa agatcttcac
     3181 gttgagattg aaggaaaaga aattttaaaa ggggttaacc tgaccctgaa aacaggagaa
     3241 attgccgcta tcatgggacc aaatggtaca ggtaaatcga ctctttctgc cgctatcatg
     3301 ggaaatccaa actatgaagt aactaaaggt gaagttttgt ttgatggcgt aaacatcctt
     3361 gagttggaag tggatgagcg tgcgcgtatg ggacttttcc ttgctatgca atacccatca
     3421 gaaatccctg gaattaccaa tgctgagttt cttcgtgccg ctatgaatgc gggtaaagaa
     3481 gatgatgaga agatttcagt tcgtgagttt attactaagc tagatgaaaa aatggaattg
     3541 ctcaacatga aagaagaaat ggcagagcgt tacctcaacg aaggcttctc tggtggtgag
     3601 aaaaaacgca atgaaattct tcaacttttg atgctggagc caacatttgc tcttttggac
     3661 gagattgact caggtcttga tattgacgct cttaaagttg tgtctaaagg tgtcaatgcc
     3721 atgcgtggtg aaggttttgg tgctatgatc attactcact accaacgtct tttgaactat
     3781 atcacacctg atatggtaca cgtgatgatg gaaggtcgtg ttgtcctttc tggtggtcca
     3841 gaattggctg cgcgtttgga acgtgaagga tacgcaaaat tagctgaaga acttggctac
     3901 gactacaagg aagaattgta attccctcgt atcttttagg agaagtaaat gactagagaa
     3961 aatattaaac ttttttcaga aatgcacgct gaaccaagct ggttggctga tctccgtcaa
     4021 aaagcttttg ataaaatcga gagtttggaa ttaccagtta ttgagcgtgt gaaatttcac
     4081 cgttggaatc tgggtgatgg aacgattaca gaaagtgagc catcagcaaa tgttccagat
     4141 ttcactgcac tagataatca cttgaagttg gtgcaagtag gaactcaaac tgtttttgag
     4201 caaattccag ttgagttggc tcaacagggt gttgtattta cagacttcca ttcagcttta
     4261 gaagaaattc cagagcttat tgaggaatta ttcatgtcat ctgtcaagta tgacgatgat
     4321 aagttggcag cctaccatac agcttatttc aacagtggtg ctgttcttta cattcctgat
     4381 aatgttgaga ttaaagaacc aatcgaaggt gttttctacc aagacagtga tagcgatgta
     4441 ccgtttaaca agcatattat gattatcgct ggtaaaaatt ctaagattag ttatctggag
     4501 cgtttagagt cacgtggtga aggaagtaca aaagcaactg caaacatcac tgtcgaagtg
     4561 attgcacgtt ctggtgctca agtgaagttt gctgccatcg accgtctagg tgaaaacgtt
     4621 actgcctaca ttagccgtcg tggtaaatta ggcaatgatg caagcattga ctgggcaatc
     4681 ggtgtcatga acgaagggaa cgtcgttgcg gactttgata gcgacttgat tggaaatggt
     4741 agccatgctg acctgaaagt tgtagctctt tcaagtggcc gtcagataca agggattgat
     4801 acccgagtga ctaactatgg ttgcaactca atcggaaata tccttcaaca tggggttatt
     4861 cttgaaaaag caaccttgac cttcaatggt attggccaca ttatcaaggg tgccaaggga
     4921 gcagatgcgc aacaagaaag tcgtgttctc atgctttcag accaagcgcg ttcagatgcc
     4981 aatccaattc ttttgattga tgaaaatgac gtaactgcag gacatgcggc ttctatcggt
     5041 caggtagatc cagaagacat gtactacctc atgagtcgtg gtttggacaa ggcaactgca
     5101 gagcgtttgg ttgttcgtgg tttccttgga tccgttatcg ttgagattcc agtcaaggag
     5161 gttcgtgatg aaatgattgc gactatcgaa gaaaaattgt caaaacgcta aggggtagcc
     5221 tatgttagat gtagaagtga ttcgcaagga ttttccaatt ttagaccaga ttgttaatga
     5281 tgaaccattg gtttatttgg acaatgctgc gacgacacaa aaaccactag cagttctgga
     5341 aacaatcaac cgctactatg agcaggacaa tgccaatgtt catcgtggcg ttcatacctt
     5401 ggcagaaagg gcgacagctt cttatgaggc agctcgtgaa accattcgta agtttatcaa
     5461 tgcagggtct acaaaggaag ttctctttac tagaggaacg acaaccagtc ttaactgggt
     5521 agcgcgttat gctgaggaag tcttgactga gggagaccag gttttgattt ctgtcatgga
     5581 acaccattct aatatcattc cttggcagga agcctgccgt aagactggag cggagcttgt
     5641 ctatgtttat ctcaaagacg gagctttgga tatggttgac ttgcgagcaa aattgacgga
     5701 caaggtacag tttgtttccc tagctcatgc ctcaaatgtt ctgggtgtgg tcaatccgat
     5761 caaagaaatc actcaaatgg cccaccaagt gggagccatc atggtggtgg atggtgctca
     5821 gtctactcct catatgaaga ttgatgttca ggacttggat gtggacttct ttgccttttc
     5881 aggtcacaag atggctggtc caactggtat cggtgttctt tacggcaaag aaaagtatct
     5941 ggaacaaatg tcaccagttg aatttggcgg cgaaatgatt gatttcgttt atgaacaatc
     6001 tgctagttgg aaggaattgc cttggaaatt cgaggctgga actcctaaca tggttggtgc
     6061 aatcggactt gctgctgcag ttgattatct ggaaaagatt ggtatggatg ccattgaagc
     6121 ccatgaacag gaattgatcg cctatgtctt tccgaaatta caggcgattg aaggactgac
     6181 catttatggt tcacaggact tggctcaacg ttcaggtgtc attgctttta acctaggcga
     6241 ccttcatcct cacgaccttg caacggcttt ggattatgaa ggtgtggcag ttcgtgcggg
     6301 tcaccactgt gcgcaaccct tgctccagta tttggatgtt ccagcaacag ctcgtgcaag
     6361 tttttatatc tacaatacca aggcagattg cgacaagcta gtcgatgcct tacaaaagac
     6421 aaaggagttt ttcaatggca ctttctaaac tagatagcct ttatatggca gtggtagcag
     6481 accattcgaa aaatccacac caccaaggga agttggaaga tgctgagcaa atcagtctca
     6541 acaatccgac ctgtggcgat gttatcaacc tctctgtcaa gtttaatgca gaagaccgtt
     6601 tggaagatat cgcttttcta aactcaggtt gtaccatctc aactgcctct gcaagcatga
     6661 tgacagaggc agttttaggc aagaccaagc aagaaattct agaacttgca accatctttt
     6721 ctgaaatggt tcaaggacaa aaagatgaca gacaagatag tcttggagat gcagccttct
     6781 tgtcaggtgt tgctaaattt cctcaacgaa tcaagtgtgc gaccctagct tggaacgccc
     6841 tgaagaaaac aattgaaaat caagaaaaac agtaaggcaa gtttcttttg tcttatgaat
     6901 cagtagaaat gaagaatgaa agaaaggata ttatggctga agaaagagta gaaccaaaac
     6961 caattgatct tggtgaatat aaatttggtt tccatgatga tgtagagcct gtcctatcga
     7021 caggaaaagg attgaatgaa gatgtcattc gtgaactatc agctgccaag ggagaacctg
     7081 agtggatgtt agagttccgt ttgaagtctt atgaaacctt taaaaaaatg cccatgcaaa
     7141 cttggggagc agacttgtca gagattgact ttgatgactt gatctactac caaaaaccat
     7201 ctgataaacc agctcgttca tgggatgagg ttcctgaaaa aattaaagaa acctttgagc
     7261 gtatcgggat tcctgaagct gagcgtgctt atctagccgg tgcctctgcc cagtacgagt
     7321 cagaagtggt ttaccacaac atgaaggaag aatttgagaa gttaggtatt atctttacag
     7381 atacggattc tgccctcaag gaatacccag acttgtttaa acaatacttt gctaagttgg
     7441 taccgccaac agataacaaa ttggctgccc ttaactcagc agtatggtct ggtggaacct
     7501 ttatctacgt accaaaaggg gtcaaggtag atattccact tcaaacttac ttccgtatca
     7561 acaacgagaa tacaggtcag tttgaacgta ccttgattat tgttgatgag ggagcaagtg
     7621 tccactacgt tgaagggtgt acagcgccaa catattcaag caacagcttg cacgctgcca
     7681 tcgtagaaat ctttgccttg gatggtgctt atatgcgtta tacaaccatc caaaactggt
     7741 ctgataacgt ttataacttg gtaacaaagc gtgctaaagc tcaaaaggat gccactgttg
     7801 agtggattga tggtaacttg ggtgccaaaa caaccatgaa atacccatct gtttaccttg
     7861 atggagaagg ggcgcgtggg actatgcttt cgattgcctt tgctaatgta gggcaacacc
     7921 aagatacggg tgctaagatg atccacaatg ctccacatac tagctcatct atcgtgtcta
     7981 aatccatcgc taaaggtgga ggtaaggttg attaccgtgg tcaagtaacc tttaacaaga
     8041 actctaagaa atctgtttct cacattgagt gtgataccat tatcatggat gacttgtcag
     8101 catcagatac cattccgttt aatgaaatcc acaactcgaa agttgctttg gaacacgaag
     8161 caaaggtttc taagatttca gaagagcaac tctattacct catgagccgt ggattgtcag
     8221 aatctgaggc aactgagatg attgttatgg gatttgtaga gccctttacg aaagaacttc
     8281 caatggaata cgcagttgag ctgaaccgct tgattagcta tgaaatggaa gggtcagttg
     8341 ggtaaaattt gattttatac tcttcgaaaa tctcttcaaa ccacgtcagc atcgccttac
     8401 cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc
     8461 aacctgcggc tagcttccta gtttgttctt tgattttgag tattagattt actcaaaatc
     8521 aaggattttg aagatgaact tgtatcaaaa aatcgcggtt taaaatcgcg attttttata
     8581 atttctcgtt aacaaagcgg acaaactgat tccaccaaac ttttaagaaa aaggcttttt
     8641 caattttctt gtctgctacc atttcgaaac tagggcgctc tgtggtgatg taaccttgac
     8701 caatcaagtc cttgtcttca taagtcaaat gggcaaccac tgttccagct tcaagtggtg
     8761 ctgggattgc tttggaatca ggtgtgaatt gaacagattg ggaagattga ttcccaacac
     8821 gttcgattag atagatatcc tctggagcca ctgcagttac tgtatcttct tttccatctt
     8881 gtacaggggc tttgctatct tgataggcat cgccttgttg aacgattttg cgaagtgtaa
     8941 atgtagaaga aatataatcc attagggaag atgtagctgt aaatcgagcg taaggattat
     9001 tgtcttgatg atctgcattt aaaacaactg tgatgactct catgcctttt tcgacagtag
     9061 taccaacaaa agactctcca gccttatctg ttgttcctgt ttttagccca tcaaaaccac
     9121 cacggtaagc aggcatactt tctaacatgt agttggttga agtgattgtc attccagcaa
     9181 aagtagaaga aggttttttg gtgatttcca agacttgtgg gtattttttg atgaggttgc
     9241 gagcaacaat agcgacatca taagcactaa gcttattttc ctcatctttt ttagaacctg
     9301 ggtaaatgtt atcccttaga gtttcattgt taagacctgt cgtattgaca acagtggcat
     9361 cctgaattcc ccattccaag agttttgccc gcatcatatc gacgaaatct ttttctgagc
     9421 cagcaatttt ctcagctagg gcaatagcgg cgctgttggc actagatacc agagttgctt
     9481 caagcaactc ttcgacagta taattacggg cctccatagg aatattactg gcttcagaat
     9541 ttgtcgtcaa ttgataagga taatcagaaa tatctacagg agtggagagg gtaatacttc
     9601 cgttttccaa agcttcatag accagataaa cagtaatcaa ttttgttatg gaagcaattt
     9661 cgacaggttg cgttgcatcc ttctcataga gaattttacc agtatttgcc tcaacagcaa
     9721 tcgcatgttt agcggcaatg gtaaaatctt gagcaacagc agtagaagca ccccctaaaa
     9781 gagagatagt taataaagtt aaaaatattt ttttcatagt agtcttattc tatcataaag
     9841 aaaaaaaata ttcttgcttt aataattcat ctgttaagct ttttgaaaat atggtaaaat
     9901 aaagtgaggg aggtaactca tgtttcgtag aaataaatta tttttttgga ccacagaaat
     9961 tttactctta accatcatct tttacctatg gagacagatg gggtctttga ttaacccttt
    10021 tgttagagtg cttaatacaa ttatgattcc atttttatta gggggctttc tttattattt
    10081 gacaaaccct attgttactt tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat
    10141 tttaattacc ttgtgtactt tggtctgggg aatggtcata ggtgttgtct atctcttacc
    10201 tattttgatt aatcagttat ctagtttgat tatatctagt caaactattt atagtcgagt
    10261 acaagactta atcatagact tatctaatta tcctgcgctc cagaatttgg atgtagaagc
    10321 tacaattcag cagttaaact tatcctatgt tgatattctt caaaatatcc taaatagcgt
    10381 atcaaatagt gtggggagcg tcttgtcagc tcttatcagt actgttttga ttttgattat
    10441 gactccagtt tttttggttt atttcttatt agatggacat aaattcttgc ccatgcttga
    10501 aagaacaatt ctaaagaggg atcgcttgca tattgcaggc ttattaaaga atttaaatgc
    10561 gacgattgct cgctatatta gtggagtttc gattgacgca atcattatag gttgtttggc
    10621 ttatattggc tatagtatta ttggtttaaa atatgcttta gtttttgcca ttttttctgg
    10681 tgtagccaat ttaattcctt atgtgggacc aagtattggt ttgattccta tgatcatcgc
    10741 aaatatattc actgatcccc atagactgct gattgcagtg atttatatgc ttgttgttca
    10801 gcaggtagat ggcaatatct tatatcctcg aatcgtagga agtgttatga aggttcatcc
    10861 aatcacgatt ttagttttac ttttgttgtc aagcaatatc tatggtgtag ttggaatgat
    10921 tgtcgcagtg ccaacctatt ctatcttgaa agaaatttct aagttcttat cccgtttgta
    10981 tgaaaatcat aaaataatga aagaacgaga aagagaatta gctaagtaaa agtcaggaga
    11041 accctgattt ttctttactg gaagtggcct ttagattaga agactgaaaa taagttaaag
    11101 tcttaaacta attttcacag ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa
    11161 ccagtggaat tccgtgtcag ggtaagttcc actggttttc atagtctatt aaagttcgaa
    11221 tgaaacctat ttatagtata ttgaaactag aatagtacac ctctaattct aaaacattgt
    11281 tagaaatcga tttgactgtc ctgatctatt cgtcctattc ttatttcatt ttactatatt
    11341 ttggtgcaat aagtgaaaag tagtccgaat aatataagga ttaattttat agtttttaaa
    11401 ctcaaatgaa ttaaaataaa gagagtacga aaattctcat ctgaaagtat tttagaataa
    11461 ttctcttcgt gaatttcttc aaaacagata gcttcatctt aggtatgtgt taattggatt
    11521 tcgtaagctc tatttacaat cgtaaagtta tgcactgaga aagttgtagt tagtcttcca
    11581 gtttgctaaa tttctcgaat agtatctttt ttaggtatgt gatttctttt tgcatttttg
    11641 agttagataa ggtataatgg ttttattgtc ttttggggtc gttacggatt cgacaggcat
    11701 tatgaggcat attttgcgac tcgtgtggcg acgtaaacgc tcagttaaat ataactgcaa
    11761 aaaataacac ttcttacgct ctagctgcct aaaaaccagc aggcgtgacc cgatttggat
    11821 tgctcgtgtt caatgacagg tcttattatt agcgagatac gattaagcct tgtctagcgg
    11881 cttgataaga gattgataga ctcgcagttt ctaggcttga gttatgtgtc gaggggctgt
    11941 taaaataata cataacctat ggttgtagac aaatatgttg gcaggtgttt ggacgtgggt
    12001 tcgactccca ccggctccat tattcctttg cattcttttg cattccttgg taaaacgttg
    12061 ttaaatcaac gttttttatt tttatctttg gtattccttt gcattctttt gctaaaaagg
    12121 gagtcacaaa cagaccctat tttaaaaaag gatacaacat ttgttgcatc ctaaaaataa
    12181 tcttttttcg acggaagata tgggattcga acccacgcac gctattacac gcctaccgcg
    12241 tttccaacac ggcctcttaa gcctcttgag taatcttcca atacttactc aaatagtcta
    12301 ccataaaggc tcttatcttg caataaaaat tctagaaata agaaaaatga tagattttga
    12361 aagaaaatga taaaaaatgc ttgacttcaa aataaagtat ggtagaatga atagtgtaaa
    12421 cgataacagg aggtgattca gtgttaaaaa cagaacgtaa acaactgatt ttagaggagt
    12481 taaatcaaca tcatgtagtt tctctagaaa aattagttag tttgctagaa acttcagaat
    12541 caacggttcg aagagacttg gatgagttgg aagcggaaaa caagcttcgt cgtgtgcatg
    12601 gtggagcaga actcccccac tccttacagg aagaagaaac cattcaagaa aaatctgtca
    12661 aaaaccttca agaaaagaag ttgctggctc agaaagcagc ctctctcatt aaagaaaaag
    12721 atgtcatctt tatcgatgct ggaacaacaa ctgctttttt gattcatgaa ttggtcaata
    12781 agaatgttac agttgtgacc aactccattc accatgccgc tcagttggtt gaaaagcaga
    12841 ttccaactgt catggttgga ggaaacgtca agacggcgac agatgctagt atcggtggcg
    12901 ttgctcttaa ccagattaac caattgcact ttgaccgtgc ctttatcgga atgaatggtg
    12961 ttgacgatgg ctattatacg actcctgata tggaggaggg agctgtgaaa agagctattt
    13021 tggagaatgc caagcagacc tacgtcttgg tggattcgtc aaaaattgga caaacttgct
    13081 ttgccaaggt agcaccactc aaacgcgcta tcgttatcac tagtcaaggg catgagctct
    13141 tgcagggtat taaggagaaa acggaggtaa tagaagtatg atttatacag tcacactcaa
    13201 tccatccatt gactatatcg ttcgtttgga ccaagtcaaa gttggtagtg taaatcgtat
    13261 ggacagtgat gataagtttg ctggtgggaa aggaatcaat gtcagccgtg tcttgaaacg
    13321 tttgaatata ccaaatacag cgacgggatt tatcggtggc tttactggta aatttatcac
    13381 agatacttta gcagaggaag aaatcgagac acgttttgtc caggtggcag aagatactcg
    13441 tatcaatgtt aaaatcaaag cagaccaaga aacagaaatc aacggaacgg gtccaactgt
    13501 tgaaccggtt cagctagaag aattgaaagc tattttatct agtctgacag cagaagatac
    13561 agttgtcttt gcaggttcaa gtgctaaaaa tctaggcaat gttatctata aggatttgat
    13621 ttccttgacg cgccagactg gtgcgcaagt ggtctgtgac tttgaaggac agaccttaat
    13681 tgatagtttg gactaccagc ctcttcttgt aaaaccaaac aatcatgaac ttggagcgat
    13741 ttttggggtt aaactcgaaa gtttagatga aattgagaaa tacgctcgtg agttactggc
    13801 taagggtgct caaaatgtta ttatctctat ggctggtgat ggcgcccttc ttgtcacatc
    13861 tgagggagct tacttcgcta aaccaatcaa aggaacagtc aaaaattcag ttggagctgg
    13921 tgattctatg gttgctggat tcacaggtga atttgtcaaa tcaaaagacg cagtagaagc
    13981 cttcaaatgg ggagtggctt gcggaacggc aactaccttc tcagatgact tggcaacggc
    14041 ggaatttatt aaagaaacat atggaaaagt tgaggtagaa aaaagatgaa aattcaagac
    14101 ctattgagaa aagatgtcat gttgctagat ttgcaggcaa ctgaaaaaac agctgtcatc
    14161 gacgagatga ttaaaaattt gacagagcac ggttatgtaa cagattttga aacatttaaa
    14221 gaaggaattt tggcgcgtga agctttgact tctactggtt tgggtgatgg aatcgcaatg
    14281 cctcacagca aaaacgctgc tgtcaaagaa gcgacagttc tatttgctaa gtcaaataag
    14341 ggtgttgact acgagagctt ggatggacaa gcaactgacc tcttcttcat gattgcagct
    14401 ccagaaggtg ccaatgatac tcacttggca gccttggcag aattgtctca atacttgatg
    14461 aaagacggtt ttgcagacaa acttcgtcaa gcaacatctg cagaccaagt tatcgaactt
    14521 tttgaccaag cttcagaaaa aactgaggaa cttgttcaag cacctgctaa tgactctggt
    14581 gactttatcg tagctgttac agcttgtaca acaggtattg cccacactta catggcccaa
    14641 gaagcccttc aaaaagtagc tgctgaaatg ggggttggta tcaaggtcga aaccaacggt
    14701 gctagcggtg ttggaaatca actaactgca gaagatatcc gtaaggctaa agctattatc
    14761 attgcagcag acaaggccgt tgaaatggat cgatttgatg gaaaaccatt gatcaatcgt
    14821 ccagttgctg acggtatccg taagacagaa gagttaatta acttggctct ttcaggagat
    14881 actgaagtct accgtgccgc taatggtgca aaagctgcaa cagcctctaa cgaaaaacaa
    14941 agccttggtg gtgccttcta caaacacttg atgagtggtg tatctcaaat gttaccattc
    15001 gttatcggtg gtggtatcat gattgccctt gccttcttga ttgacggtgc tttgggtgtt
    15061 ccaaatgaaa accttggcaa tcttggttct taccatgagt tagcttctat gttcatgaaa
    15121 attggtggag ctgcctttgg tttgatgctg ccagtctttg cgggttatgt tgcctactct
    15181 attgctgaaa aaccaggttt ggtagcaggt ttcgtggctg gtgctattgc caaagaaggt
    15241 tttgcctttg gtaaaattcc ttatgccgca ggtggtgaag caacttcaac tcttgcaggt
    15301 gtctcatctg gtttcctagg tgcccttgtt ggtggattta tcgcaggtgc cttggttctt
    15361 gccatcaaga aatacgttaa agttcctcgt tcactcgaag gtgctaaatc aatccttcta
    15421 ttgccacttc ttggaacaat cttgacagga tttgttatgc tagctgtaaa tatcccaatg
    15481 gctgcaatca atactgctat gaatgacttc ctaggcggtc ttggaggagg ttcagctgtc
    15541 cttcttggta tcgtccttgg tggaatgatg gctgttgaca tgggtggacc agttaataaa
    15601 gcagcttatg tctttggtac aggtacgctt gcagcaactg tttcttcagg tggttctgta
    15661 gccatggcag cagttatggc tggaggaatg gtgccaccac ttgcaatctt tgtcgcaact
    15721 cttcttttca aagataaatt tactaaggaa gaacgtaact ctggtttgac aaacatcatc
    15781 atgggcttgt catttatcac tgagggagcg attccatttg gtgccgctga cccagctcgt
    15841 gcgattccaa gcttcatcct tggttcagca gtagcaggtg gactcgttgg tcttactggt
    15901 atcaaactca tggcgccaca cggaggaatc ttcgttatcg cccttacttc aaatgctctc
    15961 ctttacctcg tttctgtctt ggtaggagca atcgtaagtg gtgtggttta tggttaccta
    16021 cgcaaaccac aagcataaaa aatagaaaaa tgaaaagatt ggaccgtttg gtgcagtctt
    16081 tttctcttcc cgaaatgcct gtgaaatatg gtataataga agaatggcaa acaagaatac
    16141 aagtacaaca agacggagac cgtctaaagc agaactggaa agaaaagaag cgattcaacg
    16201 aatgttgatt tcgttaggaa ttgcgatttt attgattttc gcagccttca aattaggggc
    16261 tgcaggtata accctttata atttaattcg cttgctagtg ggtagcctag cttatctggc
    16321 gatattcggc ctattaatct atctcttctt tttcaagtgg atacgaaaac aggaaggact
    16381 cttatctggc tttttcacca tatttgctgg cttactcttg atttttgagg cctacttggt
    16441 ttggaaatat ggtttggaca agtccgttct aaaagggacc atggctcagg ttgtgacaga
    16501 tctgactggt tttcgaacga ctagctttgc tggagggggc ttgatcgggg tcgctcttta
    16561 tattccaaca gcctttctct tttcaaatat cggaacttac tttattggtt ctatcttgat
    16621 tttagtgggt tctctcctag tcagcccttg gtctgtttac gatattgctg aatttttcag
    16681 tagaggcttt gccaaatggt gggaagggca cgagcgtcga aaagaggaac gctttgtcaa
    16741 acaagaagaa aaagctcgcc aaaaggctga gaaagaggct agattagaac aagaagagac
    16801 tgaaaaagcc ttactcgatt tgcctcctgt tgatatggaa acgggtgaaa ttctgacaga
    16861 ggaagctgtt caaaatcttc cacctattcc agaagaaaag tgggtggaac cagaaatcat
    16921 cctgcctcaa gctgaactta aattccctga acaggaagat gactcagatg acgaagatgt
    16981 tcaggtcgat ttttcagcca aagaagccct tgaatacaaa cttccaagct tacaactctt
    17041 tgcaccagat aaaccaaaag atcagtctaa agagaagaaa attgtcagag aaaatatcaa
    17101 aatcttagaa gcaacctttg ctagctttgg tattaaggta acagttgaac gggccgaaat
    17161 tgggccatca gtgaccaagt atgaagtcaa gccggctgtt ggtgtaaggg tcaaccgcat
    17221 ttccaatcta tcagatgacc tcgctctagc cttggctgcc aaagatgtcc ggattgaagc
    17281 accaatccct gggaaatccc taatcggaat tgaagtgccc aactccgata ttgccactgt
    17341 atctttccga gaactatggg aacaatcgca aacgaaagca gaaaatttct tggaaattcc
    17401 tttagggaag gctgttaatg gaaccgcaag agcttttgac ctttctaaaa tgccccactt
    17461 gctagttgca ggttcaacgg gttcagggaa gtcagtagca gttaacggca ttattgctag
    17521 cattctcatg aaggcgagac cagatcaagt taaatttatg atggtcgatc ccaagatggt
    17581 tgagttatct gtttacaatg atattcccca cctcttgatt ccagtcgtga ccaatccacg
    17641 caaagccagc aaggctctgc aaaaggttgt ggatgaaatg gaaaaccgtt atgaactctt
    17701 tgccaaggtg ggagttcgga atattgcagg ttttaatgcc aaggtagaag agttcaattc
    17761 ccagtctgag tacaagcaaa ttccgctacc attcattgtc gtgattgtgg atgagttggc
    17821 tgacctcatg atggtggcca gcaaggaagt ggaagatgct atcatccgtc ttgggcagaa
    17881 ggcgcgtgct gcaggtatcc acatgattct tgcaactcag cgtccatctg ttgatgtcat
    17941 ctctggtttg attaaggcca atgttccatc tcgtgtagca tttgcggttt catcaggaac
    18001 agactcccgt acgattttgg atgaaaatgg agcagaaaaa cttcttggtc gaggagacat
    18061 gctctttaaa ccaattgatg aaaatcatcc agttcgtctc caaggctcct ttatctcgga
    18121 tgacgatgtt gagcgcattg tgaacttcat caagactcag gcagatgcag actacgatga
    18181 gagttttgat ccaggtgagg tttctgaaaa tgaaggagaa ttttcggatg gagatgctgg
    18241 tggtgatccg ctttttgaag aagctaagtc tttggttatc gaaacacaga aagccagtgc
    18301 atccatgatt cagcgtcgtt tgtcagttgg atttaaccgt gcgacccgtc tcatggaaga
    18361 gcttgagatg gcaggtgtca ttggtccagc tgaaggtacc aagccaagaa aagtattgca
    18421 gcaataaaaa atagcttctt tccaaggttg gaaggaagct atttttctgg ttattgatta
    18481 cttttatttt ctgaagttgg agtattgggc tgtttttcat tttcagtggc aggtttactt
    18541 gtagcaggtg tagtagagtc ctgagttgct gttttctgct cttctttttt ctcttccttg
    18601 acgctagatt ttggcgtttc ttcttgttgt gttttttctt gagaagtgtt attttcctta
    18661 tttggagtag tattttcctg aggggattct ttttgaattt ctttgacaaa ggttgtcgtc
    18721 tggcttgtcg taggttcttt tttggtattt ttattattat ccaaggcatt catgatcgtg
    18781 atagtcgcag taatcaagcc gaggatacta ccgatagtag taatggtttt ttgaaaaaca
    18841 gtaaagcctt ttttgatatg ttctgttttc ggttttgaag ttctacgata attagacatg
    18901 cattctctcc tttgattatg acttattata ctctgtttct ttaaaaaaat cttaaaaaaa
    18961 gagaaattgc cctttcttgt cgcaagctct gtttcatgat acaatagagg gagtgatttt
    19021 agaaagcgtg agaaacatga tttactttga taattcagcg acgaccaagc cttatcctga
    19081 agcccttgaa acctatatgc aggtcgcttc aaaaatttta ggaaacccat ctagtctcca
    19141 tcgtttggga gaccaagcaa cacgaatatt agatgcttct cgccaacaga ttgcagattt
    19201 aatcggtaag aaaagcgatg aaatcttctt tacctctggt ggaacagaag gggataactg
    19261 ggttatcaag ggtgtggcct ttgaaaaagc tcagtttggc aagcacatca ttgtttcagc
    19321 cattgaacat ctagcagtca aagagtcagc cctctggttg aaaagtcaag gatttgaagt
    19381 ggattttgct cccgttgata agaaaggctt tgtcgatgtt gaggcgttag cagatttgat
    19441 acgtcctgat acgaccctcg tttccatcgt ggcagttaac aatgaaattg gctctgttca
    19501 gcccattgag gctatttcag aattgttggc agatcagccg actatttctt tccacgttga
    19561 tgcggttcag gcgcttgcca agattccgac tgaaaagtat ctgacagaac gggtggattg
    19621 cgcgactttc tctggtcaca agttccacgg agttcgtggt gttggttttg tctatatcaa
    19681 gtctggcaag aagattacgc ctcttttaac aggtggtggt caggagcgcg actatcgttc
    19741 gacaactgaa aatgtggcag ggattgcagc gacagccaag gctctgcgtt tgtctatgga
    19801 aaaactggat atctttagga gtaagacagg gcagatgaag gcagtgattc gccaagctct
    19861 tttagattat ccagatatat ttatcttttc agctgaggaa gactttgccc ctcatatcct
    19921 gacttttgga atcaagggtg ttcgtggtga agtcatcgtt cacgcctttg aagactatga
    19981 tattttcatc tcaacaacct ctgcttgttc gtccaaggct gggaaacctg caggtacctt
    20041 gattgccatg ggagtggata aggataaggc ccagtcagct gtgcgtctta gtctagacct
    20101 tgaaaatgat atgagtcagg tcgagcagtt tttgaccaag ttaaaattga tttacaatca
    20161 aactagaaaa gtaagatagg agcattcatg cagtattcag aaattatgat tcgctacggt
    20221 gagctgtcaa ccaagggtaa aaaccgtatg cgtttcatca ataaacttcg caataatatt
    20281 tcagacgttt tgtctatcta tccccaagtt aaggtaaggg cagatcgcga ccgtgcccac
    20341 gctcacctca atggagcaga ttacacagca gtagcagaat cgctcaaaca agtatttgga
    20401 attcagaatt tttctcctgt ttataaggtt gaaaaatctg tagaagtttt gaagtcttct
    20461 gtccaagaga ttatgcggga catctacaag gaaggtatga cctttaagat ttctagcaag
    20521 cgtagcgacc acaactttga acttgatagt cgtgaactca accaaacact tggaggggct
    20581 gtattcgaag ccattccaaa tgtgcaagtt caaatgaaaa gtcctgacat caatcttcag
    20641 gtggagattc gtgaagaagc agcctatctt tcttatgaaa ccattcgtgg ggctggtggt
    20701 ttgccagttg gaacttcagg taaagggatg ctcatgttgt caggagggat tgactcacct
    20761 gtagcaggtt atcttgctct taagcgtggg gtggatatcg aggcagttca ctttgctagt
    20821 ccaccatata ctagtcctgg tgccctcaag aaagcgcagg acttgacccg taaattgacc
    20881 aagtttggcg gaaatatcca gtttattgag gtgcctttca cagagattca agaggaaatc
    20941 aaagccaaag cgccagaagc ttatttgatg actctaactc gtcgctttat gatgcggatt
    21001 actgaccgta ttcgtgaggt acgaaatggt ttggttatca tcaatgggga aagtctaggt
    21061 caagtagcca gccaaaccct tgaaagtatg aaggctatca atgctgttac caacactccc
    21121 atcattcgtc ctgtggttac catggacaag ttggaaatca ttgacatcgc ccaggaaatc
    21181 gatacctttg acatttcaat ccaaccgttt gaagactgtt gtaccatttt tgcaccagat
    21241 cgtccaaaaa caaatcctaa aattaagaat gcggagcagt acgaagcgcg tatggatgtt
    21301 gaaggcttgg ttgagcgagc agtggctgga atcatgatta ctgaaatcac acctcaagcc
    21361 gaaaaagatg aagttgatga cttgattgac aatctgctct aattcagaaa atccaaaaga
    21421 atagcgaaaa tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa aaactaactt
    21481 ttttctattt ttatgatata atgatataaa attttgaata tagagagttt tctgacaatg
    21541 aatcaatcct acttttatct aaaaatgaaa gaacacaaac tcaaggttcc ttatacaggt
    21601 aaggagcgcc gtgtacgtat tcttcttcct aaagattatg agaaagatac agaccgttcc
    21661 tatcctgttg tatactttca tgacgggcaa aatgtttttt atagcaaaga gtctttcatt
    21721 ggacattcat ggaagattat cccagctatc aaacgaaatt cggatatcag tcgcatgatt
    21781 gtcgttgcta ttgacaatga tggtatgggg cggatgaatg agtatgcggc ttggaagttc
    21841 caaaaatctc ctatcccagg gcagcagttt ggtggtaagg gtgtggagta tgctgagttt
    21901 gtcatggagg tggtcaagcc ttttatcgat gagacctatc gtacaaaagc agactgccag
    21961 catacggcta tgattggttc ctcactagga ggcaatatta cccagtttat cggtttggaa
    22021 taccaagacc aaattggttg cttgggcgtt ttttcatctg caaactggct ccaccaagaa
    22081 gcctttaacc gctatatcga gtgccagaaa ctatcgcctg accagcgcat cttcatctat
    22141 gtaggaacag aagaagcaga tgatacagac aagaccttga tggatggcaa tatcaaacaa
    22201 gcctacatcg actcgtcgct ttgctattac catgatttga tagcaggggg agtacatctg
    22261 gataatcttg tgctaaaagt tcagtctggt gccatccata gtgaaatccc ttggtcagaa
    22321 aatttaccag attgtctgag attttttgca gaaaaatggt aagttaagaa agaaaaaaac
    22381 gaaatgcata ttgaatatct tagccactgg agtggtcatc ttaaccgtga aatgtacctt
    22441 aaccgttatg gacatgctgg gattccagtt gtggtctttg cttcatcagg tggtagtcac
    22501 aacgaatact atgattttgg catgattgat gcctgcactt cctttatcga ggaaggccgt
    22561 gtccagttct ttaccctatc tagtgtggat ggtgagagct ggttggctac ttggaaaaat
    22621 gctcatgacc aagcggaaat gcaccgttcc tacgaacgtt atgtgattga ggaggccatt
    22681 ccttttatca agcacaagac aggttggttt gatggcatga tgacgacagg ttgctctatg
    22741 ggagcctatc atgcactcaa tttcttcctc cagcatccag atgtctttac caaagtgatt
    22801 gctctcagtg gtgtttacga cgcacgtttc tttgtcggtg attactacaa cgatgatgct
    22861 atttaccaaa actcgccagt agattatatt tggaaccaaa acgacggctg gtttattgac
    22921 cgttaccgtc aggcagagat tgtgctgtgt acggggcttg gagcctggga acaagatggt
    22981 ttgccatcct tttacaagct caaagaagcc tttgacaaga aacaaattcc agcctggttt
    23041 gctgaatggg gacatgatgt cgcccatgac tgggaatggt ggcgtaaaca aatgccttat
    23101 ttcctcggta atctctattt ataaaaggag ttacctatga attaccttgt tatttctccc
    23161 tactatccac aaaactttca acagtttacc atcgaactag ctaataaagg catcacagtc
    23221 ttgggaattg gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa tagcttgatc
    23281 gagtattttc gtgttgataa tcttgagaac atagatgaag tcaaacgtgc agttgctttt
    23341 ctcttttata aacatggtcc aattgaccgc atcgagtctc acaatgaata ctggcttgag
    23401 ctagacgcaa cactcagaga ataattcaat gtttttggtg ccaaaccaga ggatctcaaa
    23461 aagacgaaat ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta
    23521 cctggagctg ttatcaagac ggaagcagat gttgatcaag cagtgaagga aatcggtctt
    23581 ccaatgattg ccaaacctga taatggagtg ggagcagccg caacctttaa acttgagaca
    23641 gaagacgata tcaatcactt caagcaagaa tgggaccatt caacccttta tttctttgaa
    23701 aaatttgtca cttccagcga aatctgtacc tttgacgggc tcgtggacaa ggatggaaag
    23761 attgtcttct caacaacctt tgactacgcc tatacaccac ttgacctcat gatttataag
    23821 atggacaatt cttattatgt gctcaaggat atggatccta aactgcgcaa gtatggggaa
    23881 gcaattgtca aagaatttgg tatgaaagaa cggtttttcc atattgagtt cttccgtgag
    23941 ggggacgatt atattaccat cgagtacaat aaccgccctg caggtggttt taccattgat
    24001 gtttataact ttgctcattc cttgaacctt tatcgtggct atgcagctat tgtcgcagga
    24061 gaggagttcc cagcgtcaga ctttgaaact cagtattgtt tggctacttc tcgccgtgca
    24121 aatgctcact atgtttattc agaagaggat ttgcttgcca aatatagcca gcagttcaag
    24181 gttaaaaaag tcatgccagc tgccttcgcg gaacttcaag gagattacct gtatatgctg
    24241 accactccga gtcgacaaga aatggagcag atgattgcag atttcggaca acgtcaagaa
    24301 taagaactat cggattaagg aaattaactc ccttaatgct tttgttttgt ctgataaaaa
    24361 ataagagcat cccaacaagg tagctatcat aaaacttgtt cgataactat ttgaagcagg
    24421 attaggtggt tagaaattga attttaatat ttcaattgag tcatagtatt gtgttttcgt
    24481 atccttaaat cagctaaaag gatccatgac gacacctata cgatatagtt ttcaagatac
    24541 caaacaagtc tattaatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    24601 tttctcaaaa cactgttttg aggttgtgga tagaactgac agagtcagta tcatatacct
    24661 acggcaaggt gaagctgacg tggtttgaag agattttcga agagtataaa atattcaggt
    24721 gacgcataga tatagttaat tgaagctttg tttgaaatct gataaaataa tgatattact
    24781 aagttttaaa aactaaagaa aagggaagat atgattacag gcgaattaaa aaataaaatc
    24841 gatcagttgt gggaaattct ttggacagaa ggaaatgcaa atcctttaac aaatattgaa
    24901 cagttgactt atctcttatt tatgaaagat ttggatactg tcgagcttgg acgtgaaagt
    24961 gatgctgaat ttctagggat tccttatgag ggagtttttc caaaagataa acctgaatac
    25021 cgttggtcaa cttttaaaaa cataggagat gctcaggaag tttatcgttt aatgactcag
    25081 gagatttttc cgtttattaa aaatctcaag ggggatacag atgatacagc cttttcacga
    25141 tatatgcgag aagctatttt tcaaataaat aaacctgcta cgcttcaaaa ggcaatttct
    25201 atcttagatg tttttccaac taggggatta gatgtagatt ttgataatga caaacaaagt
    25261 attactgata tcggagatat ctatgaatat ctgttatcaa aattgtcgac cgcaggtaaa
    25321 aatggacagt tccgtacacc tcgtcacatc atcgatatga tggttgagtt gatgcaacca
    25381 actatcaaag atatcatctc agatcccgct atgggttctg ctggcttctt agtatccgct
    25441 agccgttact taaagcgtaa gaaagatgaa tgggaaacca atacagataa tatcaatcat
    25501 tttcataatc agatgtttca tggaaatgat acggatacga ctatgttgag acttggggcg
    25561 atgaacatga tgctacatgg agtagaaaac ccacaaatca gttaccttga ctcgctgtct
    25621 caagataatg aagaagccga taaatatact ttggttttaa caaatcctcc ttttaagggc
    25681 tcacttgact acaattcaac ctataatgac cttcttgcaa ccgtaaaaac caaaaaacag
    25741 aattactctt tctttctctt ttcttgcgaa ctttaaaacc aggtggacga gcagcagtta
    25801 tcgtacctga tggtgtcctt tttggttcgt ctaaagctca taaaggaatt cgtcaggaaa
    25861 ttgtagagaa ccataagatt aatgctataa tctcaatgcc tagtggtgtt ttcaagcctt
    25921 atgctggagt ttcaactgcc attctcatct ttacaaaaac tggcaatggt ggtaccgaca
    25981 aggtctggtt ttacgatatg aaagcggatg gtttgagttt ggatgataaa tgacaaccaa
    26041 ttagtgacaa tgatattcca gatattatcg aacgctttca tcatcttgaa aaagaagtag
    26101 aacgtcagag aacggatcaa tctttctttg ttccagttgc tgagataaag gaaaatgatt
    26161 atgatttgtc tatcaataaa tataaagaga ttgagtatga aaaagttgag tatgaaccaa
    26221 cagaagtcat attaaagaaa atcaatgatt tagaaaaaga aattcaagct ggcttggctg
    26281 aattggaaaa attactcaag tagggaggtg gctgtatgaa aaaagtgaag ttgggggaag
    26341 tcttatctct aaaaaaaggc aagaaagcca ctgtacttgc tgaacaaaca actctaagcc
    26401 aacgttatat tcaaatagat gatttaagaa ataataataa tttaaaattc actgaaagtt
    26461 taaatatgac tgaagcactc ccagatgata ttctgatagc atgggatgga gctaatgcag
    26521 gaacagttgg ttatggatta tcgggagctg ttggtagtac aattacggtc ttaaaaaaga
    26581 atgagcgata caaagaaaaa attatatcag attacttggg agtctttttg gaaagtaaat
    26641 ccagttttct tatggaagct tattacaaat gagaaaacaa aattaaaaat taagagaatt
    26701 tcctctggaa ctagtgggag tatgaaaaat atttcgaaat cacaattgtt acaaattaga
    26761 gttcccttcc ccccactagc cctccaaaat gagttcgcag actttgtagc cctggtcgac
    26821 aaatcacaat tggcaatcca aaaatctctg gaagaacttg aaactttgaa gaaatctctg
    26881 atgcaggagt attttggctg atattctgcc attgtaatta cggtaatgat ttgttataat
    26941 acttcaaagg aggaaatcag atggtagtaa aaacaagaaa acaaggaaat tcaatcacca
    27001 ttacgattcc aagtgaattt aatattccaa gtggtgttaa atacgaagcg aaattgttac
    27061 caagtggtga gattatcttt actcctgaag aattggggca gcaggtttct tatgtatctg
    27121 atgatgcctt tgacttaaat ttagataaaa tatttgacga atacgacgat gttttcaaag
    27181 ctttggtgga aaaatgacaa tctatctgac agaaaagcaa attgaaaaaa taaattcttt
    27241 agcaattcaa cggtattctc caaatgagaa aattcaaaca gttagtcctt ctgccttaaa
    27301 tatgattgtg aacttaccag aacaatttgt ctttgggaag cctctttatc caacaatttt
    27361 tgataaagca acgatactat ttgtccaatt gataaagaag catgtttttg ctaatgctaa
    27421 taaaagaact gctttcttcg ttttggtcaa atttttacaa ttaaacggct atcgtttttc
    27481 tgtaacggta gaagaagcag taaaaatgtg tgtaaccatc gcagtagaag ctttaactga
    27541 tgaaaaaatg acaagctact ccaaatgggt ttctgaacat tctgttagag aaaaggtcaa
    27601 aaagtaacct agtatgctgg atttgaatga gcacaagaaa ataaatgaac agacaatatt
    27661 agaattctgt aatgcagaaa ctgatattgt ctctttttat tgatgaataa gaaagtgaga
    27721 aattatggaa tcaaaagtta caattatcat gcaagaaatg ttacctcttt taaataatga
    27781 acaattacta gcgttgagag agagtttaga acatcatcta gtagacggaa aaaagcagca
    27841 gaagtattcg aataataacc tgttgcaact atttattacc gccaagcagg tagagggctg
    27901 tagctcaaaa acaattcgtt attaccagag gacgattgaa aacttgttta atgctattaa
    27961 agagtctgtg acacaactca caacagatga tttaaggagt tatttagcaa attaccagtc
    28021 tgaaaaggat tgtagtaagg caaacttaga caatattagg cgtatattgt cttctttttt
    28081 tgcttggctt gagcaagagg aatatatcat taaaaatccc attcgacgga taaagaaaat
    28141 taagactgag caaaatgtga aggaaactta tactgatgaa catttggaaa ttatgcgtga
    28201 taactgtgaa aatttgagag atttggcaat aatagaccta ctagtatcgt gtaggggagc
    28261 ttgtacagtt gaatcgttca gatattgatt ttgaaaacag agagtgtgtt gtctttggta
    28321 aaggaaagaa ggagagacca gtatattttg acgctcggac gaaaattcat ttaagaaatt
    28381 atcttaacga cagaaaagat agtcaccctg ctctttttgt aacgctagtt ggaaaagccc
    28441 agagacttgg aattgctggt gtagagattc gcttaagaaa attaggagac aaactcggca
    28501 tacaaaaggt tcacccacat aagttcagaa gaactttagc gactaaggca attgataaag
    28561 gtatgcctat cgaacaagtc caaaaactgc taggtcatag caagattgac acaaccctgg
    28621 cctatgccat ggtcaatcaa aataatgtca agcattcaca ccaaaaattc atctcttaaa
    28681 agcaaatccc gatattccga ggaggtggtt gcatgaaaaa agtgaaatta gggcaagtgg
    28741 ctacttttat caatggctat gcttttaaac ctcaagattg gtcatctgaa gggaaagaga
    28801 ttatcagaat acagaatctg actaaaactt caaaagggat aaattattat tcgggtacga
    28861 ttgataaaaa atacattgtt gaagctggtg atattcttat ttcgtggtcg ggtacattag
    28921 gggtttttca gtggtgtgga agatccgcag tgttaaatca gcacattttt aaagtggttt
    28981 ttgataagat agatatagat aaatcgtatt ttaaatatgt tgttgaaaaa ggtttgcaag
    29041 atgctgtaaa acatactcat ggttccacaa tgaaacattt aactaaaaaa tattttgata
    29101 atattatggt ttcatataca aatttgagag agcaacaaag aattgcaagt gagctggatt
    29161 tgttaagcaa gctgatttta aggagacaag aacaacttga agagcttaat ctacttgtaa
    29221 aatcccgatt taacgagatg tttggggaaa ataaaatatt tgaaagcatt gataacttat
    29281 ttgatattat agatggtgat aggggcaaaa attatcctaa atcagatgag ttgtttagtg
    29341 agga
//
LOCUS       DAVFJR010000027        28270 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVFJR010000027 DAVFJR010000000
VERSION     DAVFJR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28270
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.028"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..321)
                     /gene="pmp23"
                     /locus_tag="VU722_001424"
     CDS             complement(<1..321)
                     /gene="pmp23"
                     /locus_tag="VU722_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU1772377.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKK"
     gene            complement(321..1295)
                     /locus_tag="VU722_001425"
     CDS             complement(321..1295)
                     /locus_tag="VU722_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU1772378.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSENLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(1303..2559)
                     /locus_tag="VU722_001426"
     CDS             complement(1303..2559)
                     /locus_tag="VU722_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU1772379.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVESLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMALIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFRETADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHIVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQAPDFRIISGGTENHLFLVDVTKIVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     AENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(2620..3051)
                     /locus_tag="VU722_001427"
     CDS             complement(2620..3051)
                     /locus_tag="VU722_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772380.1"
                     /translation="MLRDLRETDVKAICEINQEALGYSFSPEDTASQLAKLSQDSHHF
                     LLGYEDAASHVLLGYVHAEVYESLYSKAGFNILALAISPQAQGQGIGKSLLQGLEQEA
                     KRRGYGFICLNSADHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(3053..3655)
                     /locus_tag="VU722_001428"
     CDS             complement(3053..3655)
                     /locus_tag="VU722_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU1772381.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDCVYQLKRR
                     PRDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TVGFRMPSHPITLDLIRETGPLIGPSANISGQTSGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTILDLSGDKVKILRQGAIKREDILAQLPEISFEEE"
     gene            complement(3639..4478)
                     /gene="prmC"
                     /locus_tag="VU722_001429"
     CDS             complement(3639..4478)
                     /gene="prmC"
                     /locus_tag="VU722_001429"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU1772382.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLATHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLEENLQVLDIGTGSGAIALALAKNRPAWSVTAADISQDALELASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREGESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPALFKKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(4478..5557)
                     /gene="prfA"
                     /locus_tag="VU722_001430"
     CDS             complement(4478..5557)
                     /gene="prfA"
                     /locus_tag="VU722_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU1772383.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(5554..6144)
                     /locus_tag="VU722_001431"
     CDS             complement(5554..6144)
                     /locus_tag="VU722_001431"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU1772384.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            6267..6449
                     /locus_tag="VU722_001432"
     CDS             6267..6449
                     /locus_tag="VU722_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU1772385.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            6586..7959
                     /gene="mnmE"
                     /locus_tag="VU722_001433"
     CDS             6586..7959
                     /gene="mnmE"
                     /locus_tag="VU722_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU1772386.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(8006..8941)
                     /gene="dapA"
                     /locus_tag="VU722_001434"
     CDS             complement(8006..8941)
                     /gene="dapA"
                     /locus_tag="VU722_001434"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU1772387.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(8997..10073)
                     /locus_tag="VU722_001435"
     CDS             complement(8997..10073)
                     /locus_tag="VU722_001435"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU1772388.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(10658..10730)
                     /locus_tag="VU722_001436"
     tRNA            complement(10658..10730)
                     /locus_tag="VU722_001436"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10695..10697),aa:Thr,seq:ggt)
     gene            complement(10830..11339)
                     /locus_tag="VU722_001437"
     CDS             complement(10830..11339)
                     /locus_tag="VU722_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU1772389.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(11337..11433)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            11462..11893
                     /locus_tag="VU722_001438"
     CDS             11462..11893
                     /locus_tag="VU722_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU1772390.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQILIIIINYILSKIYIFRK"
     gene            11975..12352
                     /gene="mscL"
                     /locus_tag="VU722_001439"
     CDS             11975..12352
                     /gene="mscL"
                     /locus_tag="VU722_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU1772391.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(12394..13488)
                     /gene="hemH"
                     /locus_tag="VU722_001440"
     CDS             complement(12394..13488)
                     /gene="hemH"
                     /locus_tag="VU722_001440"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU1772392.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEDRLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILEEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            13643..14866
                     /gene="pepT"
                     /locus_tag="VU722_001441"
     CDS             13643..14866
                     /gene="pepT"
                     /locus_tag="VU722_001441"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU1772393.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNLLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(14902..15531)
                     /locus_tag="VU722_001442"
     CDS             complement(14902..15531)
                     /locus_tag="VU722_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772394.1"
                     /translation="MSKANQLLEQIHEEGIRKSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETGSDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            15496..15717
                     /locus_tag="VU722_001443"
     CDS             15496..15717
                     /locus_tag="VU722_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772395.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(15794..16441)
                     /locus_tag="VU722_001444"
                     /pseudo
     CDS             complement(15794..16441)
                     /locus_tag="VU722_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(16545..17105)
                     /locus_tag="VU722_001445"
                     /pseudo
     CDS             complement(16545..17105)
                     /locus_tag="VU722_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(17343..19712)
                     /locus_tag="VU722_001446"
                     /pseudo
     CDS             complement(17343..19712)
                     /locus_tag="VU722_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19910..22390)
                     /locus_tag="VU722_001447"
     CDS             complement(19910..22390)
                     /locus_tag="VU722_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU1772396.1"
                     /translation="MKFNKKYLAGSVAVLALSVCSYELGRHQAGQAKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQIAYRTANGVAVPHGDHYHFIPYSQMSPLEEKLA
                     RMIAIKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENHLSKKTQETHALVAKKESVASRDREFYDKAYNLLTQAHK
                     ALSENKGRTSDFHALDKLAERLNNESSNKVKLVDDLLTFLAPITHPERLGKPNAQIAY
                     TDDEIKLAKLAGKYTTEDGYIFDEHDIESDEGNAYVTPHLNHSHWIKKDSLSEAERAA
                     AQAYAKEKGLQAPNSTEATEAKTEATGTEAIYNRVKAEKKVPLEKIPNHLQYTVAVQN
                     GHFIIPHFDHYHNLKFAWFDEGLYSAPEGYTLEDLFATVKYYVEHPDQRPHSDNGWGN
                     ASDHVRKHQADQDSKPDENKEHEEVSEPTRPESDEEENHAGLNPSADNLYKPSTDTEE
                     TEEEAEDTTEEAEVPQVERSIIEVKITEAEALLAKVTDSRIQQNAMETLAGLQSSLLL
                     GTKDNNTILAEVDSLFALLKESKPTPIQ"
     gene            complement(22398..23315)
                     /gene="adcAII"
                     /locus_tag="VU722_001448"
     CDS             complement(22398..23315)
                     /gene="adcAII"
                     /locus_tag="VU722_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU1772397.1"
                     /translation="MKKQNLFLVLLSIFLVCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            complement(23458..24849)
                     /locus_tag="VU722_001449"
     CDS             complement(23458..24849)
                     /locus_tag="VU722_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU1772398.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLA
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWHIKLDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSQLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLMPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNTCTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMETWIAFLVALLIGSLI
                     YFTYGYKHSTIEE"
     gene            complement(24971..25537)
                     /gene="sdbB"
                     /locus_tag="VU722_001450"
     CDS             complement(24971..25537)
                     /gene="sdbB"
                     /locus_tag="VU722_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU1772399.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEEAKKTQAPEQSPKQQQQTPVQ
                     QIAVGKEAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPD
                     RDFEILTVIAPGIQGEKTVEQFPQWFQDQGYKDIPVLYDTKATTFQAYQIRSIPTEYL
                     IDSQEKIGKIQFGVISNADAEAAFKEMN"
     gene            complement(25548..26255)
                     /gene="ccdA2"
                     /locus_tag="VU722_001451"
     CDS             complement(25548..26255)
                     /gene="ccdA2"
                     /locus_tag="VU722_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU1772400.1"
                     /translation="METIVFSISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWLGLIRTLCFIAGISLIFFILGFGAGYFGHVLYANWFRYVMGVIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSVFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMAIPFLVLALASGIVMPYFSKLKRHMMLLKKIGGFLIILM
                     GILLLLGQVNVLAGIFE"
     gene            complement(26486..26902)
                     /locus_tag="VU722_001452"
     CDS             complement(26486..26902)
                     /locus_tag="VU722_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772401.1"
                     /translation="MKAALNSLKDVPANASDSKPAQDKKDAKQGTEDSKDSAKMTETT
                     SVPPGVIVVSLLVLLGVIAFWLVRRKKESEIQQLSTELTKILGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETEAKLVEELKSILAKLK"
     gene            complement(27189..27686)
                     /locus_tag="VU722_001453"
     CDS             complement(27189..27686)
                     /locus_tag="VU722_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU1772402.1"
                     /translation="MKKIEVKGLAKTVKDKAIQNIENAQDETTLNTAKNNGITNIGKV
                     TLPRTTKKAEAKEAINAAAEAKKTEISNRFDLTIEDKSRALQQVDQEANDAKIAVDKG
                     VTNKDVEQAKVVGIDAINNINPQPTSRPLSTPQPQPSTPTQPDQGDTETPTTPSSPSA
                     QPSQL"
     gene            complement(27640..27813)
                     /locus_tag="VU722_001454"
     CDS             complement(27640..27813)
                     /locus_tag="VU722_001454"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772403.1"
                     /translation="MSDAVTIPTPTTPTLDKDGAKNEVEQAFSTKTSNIDKDNSLTNE
                     KNRSERISENSKR"
     gene            complement(28092..>28270)
                     /locus_tag="VU722_001455"
     CDS             complement(28092..>28270)
                     /locus_tag="VU722_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772404.1"
                     /translation="VEDKACNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLR
                     MNLIAGITNHELGF"
BASE COUNT         8122 a         5909 c         5189 g         9050 t
ORIGIN      
        1 cttcttctgc gccagataga gattgcctgt cagagtttga atgccttgcc gaatgctaga
       61 ggcattatca ttgatggtgt tggttgaacc acttgcagac tcactagact gcataacatc
      121 gccttctttt ccttttgttt cagtataaat catagcaagc acaagctctt cgtttgctgg
      181 agtgtctttt tcactcaaga tttctcgcac catgggttga taggtcatga cttgtttgac
      241 atcttgatga acgcggtaag ctttatagcc agcaaaaagg aagactgcta gtacaagcac
      301 tcttcgaatt cgtttaaaca ttatttactt tggatatcct cgatattttt gattaagata
      361 gagtaggttc cattttcgtt ttggataaac tcaacagact cggcgtcttg atagacgtta
      421 ttgggaacga tgagttcaat tccatttgat aaggagagtt tttggttttc aaatttcttt
      481 aattggcgac tggcatcaat ttcatcaaat tgaacaggtt ctggtacggc ttctttgact
      541 tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc
      601 tcaggtgaca attcattgct ttcttctaga ttgttgaaaa tagctgattt gaccttggat
      661 tgaaattgaa aatcatctgt gttaaaagat tcggcaattc tctgggctgt tttttccagt
      721 tccttgatgg atttcttagg tgaaatcttg ggggcaacag ctaggagatt ttctgaaaaa
      781 tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa tcagatggta cttgcgactc
      841 tgaagattga ctaccaaggc ctcgtcagca cccgttccaa atccaggcag gttattctga
      901 gtcagcttga ttggattatc aacttctcct ccgaggtggg tcaaggtctc ccgcagggca
      961 attcgcaaga aagcgaaatg ttctacacct tctttagaaa attgaacaaa aatcaagtca
     1021 ttggtcttga gattttcaga aatgctaaac tcctctttcc agagattagc cagcgttact
     1081 gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc
     1141 ccagtcttgg cttcatctga atacacatgt tcaatttttt tacgcaggta ttcttcgatt
     1201 tttggagtaa tattgagaaa cttatctgct aagaacagct cggtatcatc cggactgaac
     1261 tggtgaataa tggctttctt aatataaatg tccataaaag ttttagtcct cgtataatgg
     1321 gaaggcatct gtcaattctt tgactgcact tctcacttct tctaatacag cctcattttc
     1381 tgcattttta agggttttaa tgatgagttc agccactttg cgactttctt cttcaccaaa
     1441 tccacgtgca gtaatggctg ctgctccgat acgaatccca cttgtcttga atggtgacaa
     1501 ggtttcgtaa gggattgaat ttttatttag ggtaatattg acttcatcca gcaagttttg
     1561 agcaactttt ccgttttcta caatcttagt cacatcaaca aggaagaggt ggttttcagt
     1621 tccgccagaa ataatacgga aatcaggggc ttgcaagaag acatccgcca tagccttgct
     1681 gttcttgata acattggcag catattcctt gaaggctgga tccaaaactt ctttgaagga
     1741 aactgcctta gcagccacaa tatgctccaa aggaccaccc tgaataccag ggaaaatagc
     1801 tgaattgatt ttcttagcta aatcctcatc attggtcaaa atcaaaccac cacgaggacc
     1861 acgaagggtt ttgtgggtcg ttgttgtagt gatatgagcg tatggcactg ggcttgggtg
     1921 aagaccagct gcaaccaagc cagcgatgtg ggccatatca accatgagct tagccccaac
     1981 agcatctgcg gtttcacgaa attttgaaaa atcgataatt tgagaatagg ctgaagcacc
     2041 agctacaatc agttttggtt ttacttcttg ggcttgtttc aagatagcat caaagtctaa
     2101 gagttccgtt tcaggatcaa cactataaga aacaaagttg taggtttgac cagagaagct
     2161 aacaggagcc ccatgagtca aatgaccacc tgctgccaaa tccattccca taaccgtatc
     2221 acctggctca atcaaagcca tgtaagccgc acagttagcc tgacttcctg agtgaggttg
     2281 gacattggca aatttagcac cgaaaatttc ttttgcgcgt tcaatggcta gagattctac
     2341 cacatctact acatcagttc caccataata acggcgtcct gggtaaccct cggcatattt
     2401 gtttgtcaag atagaccctt gagctgccat aacagccttg gaaactacgt tttccgaagc
     2461 aatcaactcg atattgtttt gttggcgttc ttcttctttg gcaatagcat tccagagatc
     2521 agcatcgtat gctttaaaat catctttatc aaaaatcata ggtcttctcc tttattttgt
     2581 gactagtcca ttagtttgat tttacaataa gaaaataaac taaaagatgc gaataaaccg
     2641 tttctgcact ttatcacaag tataaccaac tttttcataa aatgcatgag ctcccagacg
     2701 atgatcggca gagtttaagc agataaaccc ataaccacgt cttttggctt cttgttccaa
     2761 cccttgtagt aaacttttac caataccttg accttgcgct tgaggtgaaa ttgctaaggc
     2821 taagatatta aatcctgctt tggaatagag tgattcgtaa acttcagcgt ggacatatcc
     2881 aagtaaaaca tgactagctg catcctcata gccaagaagg aaatgatggg aatcctgaga
     2941 taatttagct agttgactag ctgtgtcctc tggactaaaa gaataaccca aagcctcttg
     3001 gttaatttca caaatggctt tcacatcagt ttctcttaaa tctcttagca tctcattcct
     3061 cctcaaaaga aatctctggc aactgagcaa gaatatcttc tcgcttaatg gccccttggc
     3121 gtaagatttt caccttgtct ccagacaaat ccaaaatagt tgaatcctgt ccagttagaa
     3181 aagcatcgtc ttccagaccc agaacttctt ggtcaaaatc cttcaaaatt tgttcaaagg
     3241 ttacaccact tgtctgacct gagatattgg cagacggccc aatcaaggga cctgtctctc
     3301 gaattaaatc cagtgtgata gggtgactgg gcatccgaaa tccaacagtt gcaaggtcag
     3361 aatttaccca atagggaact cggtcattgg cttcgagaat aatggtcaag gggcctggca
     3421 aaaaggtctc tacaagtttt tgtagataag ctggctgatt ctttgaaaag tgcaagatgt
     3481 cctctaaaga ggcaacattg agattgagcg ccttgtctct aggacgacgt ttgagctggt
     3541 aaacacagtc aactgctttt tcgtctagcg ccttggcaaa aagaccataa accgtctctg
     3601 taggtagaac gacagctcca ccattttcca actcttgtct aatcctgtcc atcatcaacc
     3661 acgaccatcc tatcttgacc aaattggtcc ttgagtgttc gaactctttt ttcaggaaga
     3721 tgtttcttaa aaagcgcagg aacactttga ccttgcttgt atccaatttc aaggtaaatc
     3781 ttaccaccat ctttgagata gtcttttgca tcttccgcaa ttctacggta aatagctagg
     3841 ccatcctcgt ctgcaaagag agctagatga ggctccgaat acaagacatt caagcctacc
     3901 tctgactcac cttcacgaga gatatagggt ggattggaaa caattatatc atatttttca
     3961 gaaatttctg taaaacagtc agatttttta aaaaatattt gaagattttg atttttagca
     4021 ttttctgatg caagctctaa ggcgtcttgg gaaatatctg ctgctgttac tgaccaagct
     4081 ggtctgtttt ttgctaatgc tagagctatg gcgccacttc cagtcccgat atctaggacc
     4141 tgaagatttt cctcaagatt ttcagttaga ataagctcca ctaactcctc tgtttctgga
     4201 cgaggaatca aaacccgttc atccaccttt aaatgcattc cataaaaatc tgcctgtcca
     4261 atgatgtact gagctggctt gtgagttgct agttgctggt aaatatcttc tacaaattgt
     4321 ttttcttcct ctgttgtcac ctcctgctgg agggcaaaaa taaagtctgt aaaagataga
     4381 tttttcagac tacgatagac aaaagagagg ctttccgctt cctctccttg tcttatcaac
     4441 tcttcttcaa aatttgaaaa taattgagct aatttcatta tttgtttaat tcttctagtt
     4501 tttgtgtttg gtcataaagc accaaggcat ccacaacttc gtccaattta ccagacaaaa
     4561 tcgtatctag tttttggagg gtcaagccga tacggtggtc tgtgacacgg ttttgtggga
     4621 agttataagt tcggattcgt tctgaacggt caccagtacc gattgtcgac ttacgctcag
     4681 cgtcctgctc atcttgagca atctgagcaa agtggtcagc aacacgggca cgaatgattt
     4741 tcatggcctt ctcacggttt ttctgctggg tacgttcttc ttgcatctca accttgatat
     4801 tggttggcaa gtgaacgata cgcacggcag tcgcaacctt attgacgttc tgaccaccag
     4861 cacctgatgc gtggtaaata tcaacacgaa gatcttttgg atcgatatcg tattctactt
     4921 cttcgacttc aggcatgaca agaactgtgg cagttgaggt atgaacacga ccttggcttt
     4981 ctgtcacggg gacacgctgc acacggtggg cacctgattc atacttaagc ttagagtata
     5041 cagactgacc tgaaaccata gcaaccactt ctttaaaacc accgacacca ttcatagagg
     5101 cttccatgac ttcaaagcgc caaccttggg cttccgcata cttttggtac atagttagca
     5161 aatctccagc gaaaagtgcc gcttcgtctc caccagctgc tccacggatt tcaaggatga
     5221 tattcttgtc atcgtttgga tcctttggaa ggagcaaaat tttcagtttt tcttcatatt
     5281 cttctttttc agccttggca tctttgagtt cttgcttggc catttcttcc aagtccgcat
     5341 ctccgcctga ttccttaatc atctcttcgg catcgacgat attttgaagg acttgtttat
     5401 actcacggta ggctattacg gtgtcacgat tggaagcttc ttcttttgaa agctccataa
     5461 aacgcttggt gtctgaaacg acatcagggt cactcagcaa ttctcctagt tcttcataac
     5521 ggtcttctac agcttgtagt tgatcataga tgttcatttt tcttcattct ccttattgat
     5581 ttcaggggca aaataatgtt tacgacaaac cgagatatag gtttcattac caccaatctg
     5641 gatctgttct ccatcgtaaa cgggcagtcc atcctgtgtt cgcaacacca tggtcgcctt
     5701 tttcttgcaa tactgacaga tggtcttgat ttcgtcaatc ttgtctgcta aaagcaagag
     5761 atatttggaa ccttcgaaca attcattgcg aaagtcattt ttcaagccaa aagccatgac
     5821 gggtatgtct aactcgtcta caacacgagc taggtcataa acatggtggc gtttgagaaa
     5881 ctgggcttca tcgaccaaaa cacagtaagg tttttctggt aggtctcgga tatagccaaa
     5941 gatatccgtt gtttcctcaa tcgcaagggc agggcgtttc atgccaattc gactcgacac
     6001 atagccaaca ccgtcacgcg tatccagagc cgaggtcata atcacaacac cttttccttg
     6061 ctcctcgtag ttataggcca ctttgagaat ctcaatcgtt ttaccagagt tcatggtccc
     6121 ataacgatag tacaactgtg ccatgtttct tgcttcacgt ccatttctaa atttttgcta
     6181 cattctagta tatcataatt ttcttaagct ttaaacggca aaatgtggta aaatggaaga
     6241 aatcaaaact agtggaggaa gctattatgc catttgtacg catcgattta tttgaaggac
     6301 gcacgctcga gcaaaagaaa gctcttgcta aggaagtaac ggaagcagtt gtccgcaaca
     6361 ctggagcccc tcaatctgct gtccatgtca tcatcaacga catgccagaa ggaacttact
     6421 tcccacaagg ggaaatgcgt actaaataag ctagcttaag cagaattgct taggcttttt
     6481 caatctccaa gtagcattca ttgaagaaat atcctaaatt tgttacaatt tgaaaagaaa
     6541 cttggagaat ttccaagaaa agagctatta attaaaggaa acattatgat tacacgtgaa
     6601 tttgatacca tcgctgctat ctctactcca ctaggtgaag gggctattgg tattgtccgc
     6661 ctgagcggaa cagacagttt tgctattgcg caaaagattt ttaaaggaaa agacttgaac
     6721 aaggttgcca gccacactct caactacggt cacattattg atcctctgac tggtaaagtc
     6781 atggacgagg ttatggttgg ggctatgaag tctccaaaga ccttcactcg tgaggatatt
     6841 atcgagatta acacccacgg tgggattgcg gtgaccaatg aaattctcca gctagctatt
     6901 cgtgaagggg ctcggttggc agaacctggt gaatttacca aacgtgcttt tttaaacggt
     6961 cgcgtagact tgacacaggc agaggctgtg atggatatca tccgtgccaa gactgacaag
     7021 gccatgaaca ttgcggtcaa acaattagac ggctcccttt ctgacctcat taacaatacc
     7081 cgtcaagaaa tcctcaatac acttgcccaa gttgaggtca atatcgacta tcctgaatat
     7141 gatgatgttg aggaagctac tactgccgtt gtccgtgaga agactatgga gtttgagcaa
     7201 ttgctaacca atcttcttag aacagcccgt cgcggcaaaa tccttcgtga aggaatttca
     7261 acagctatca tcggacgtcc caacgttggg aaatccagcc ttctcaacaa cctcttgcgt
     7321 gaggacaagg ctatcgtaac agatatcgct gggacaacac gagatgtcat cgaagagtac
     7381 gtcaacatca atggtgtacc tctcaaattg attgatacag ccggtattcg tgaaacagat
     7441 gacatagtgg aacaaatcgg tgttgagcgt tcgaaaaaag cccttaagga agctgaccta
     7501 gttctgctag tactaaacgc tagtgaacca ctaaccgccc aagatcgcca actcctagaa
     7561 atcagccaag ataccaatcg cattattcta cttaataaaa ccgacctgcc agaaacgatt
     7621 gaaacttcga aactacctga agacgttatc cgtatttcag tccttaaaaa ccaaaacatc
     7681 gacaagattg aagagcgaat caacaacctc ttctttgaaa atgctggctt ggtcgagcaa
     7741 gatgctacct acttgtcaaa cgcccgtcac atttccctga ttgaaaaagc agttgaaagc
     7801 ctacaagccg ttaatcaagg tcttgaacta gggatgccag ttgacttgct tcaagttgac
     7861 ttgacccgta cttgggaaat tctaggagaa atcactggag atgctgctcc agatgaactc
     7921 atcacccaac tctttagcca attctgttta ggaaaataag aaaaatccat gatccttcat
     7981 tcggtcatgg attttattgt ctttattagt aatctggtct taagacccct gttacagttg
     8041 ccttagttgc ttcgtagtcg ccatctacga caaccttgat aatgcgtttg gcatcttctt
     8101 ctggtgctgg aacaagaggt agacgagtgg gtccagcttc aaatcccata tagttaagaa
     8161 ttgccttaac tggagcagga cttggataag agaagagagc attaacctta ggaatgaatt
     8221 tacgctgaat tgctgcggct ttcttcatat cgctttctgc aatggcagta aacatctcgt
     8281 gcatttcatc cccatttgta tgagaggcaa cagaaataac cccatccgcc ccaaggttca
     8341 tggcatggaa agcatctcca tcctcacctg tataaatcaa gaactcttca ggcttgtgct
     8401 caatcaagta agccatatta gccaaactag tacattcttt gacaccgata atatttggat
     8461 ggtcagccaa acgaagcatg gtttctggag tcaattcgac aactacacgc cctggaatgt
     8521 tatagataat aattggtagg tcagaagcat ctgcaatagc cttaaagtgc tgatacatcc
     8581 cttcttgaga aggtttgttg tagtaaggaa caatagcaag cccagctgcg aaaccaccaa
     8641 attccgctac ttctttgaca aactcaatag agtcacgcgt atcattagta cctacacccg
     8701 caatcaaagg aacgcgtcca ttgacaacct tttgtacagc cgcaaacaac tccaactcct
     8761 catcgtgggt caaagttgga ctctcagcag tcgttcctgc gagaagaatt ccatccgtat
     8821 gatgggccaa taaatgctca atcaaggctg gaatagcatc aaagttaatg gaaccatcct
     8881 catggaaggg ggtaataaag gctgtaatga ttttacattc ttttaaatct tgataagaca
     8941 cgaaaacacc tctctatttc aaagaaggag ttcatctgaa ctcctaaacg atatgactat
     9001 tttaattcaa atttcaattc ggctgttgga cgaaccaatc cacgttcatg aagagtttca
     9061 gcaatctgaa ctgagttcca agcagcacct ttgagaaggt tatctgaaac aacccacatg
     9121 tgaattcctt tttctgcatc caagtcttta cggatacgac caacaaaggt atcacgcgaa
     9181 ccaactgcat tgatggcttg aggatagatt tgatgagcta catcatcttc aagaacagca
     9241 cctgggaagg ctgcgatagc tgcttttact tcttcgattg gagccacttc ttttgtttcg
     9301 atataaacag actcagagtg agctgacaag actggaatac gcacacatgt tgcagatact
     9361 gcaatgctat catcttccat aattttctta gtttccttgg tcatcttcat ctcttcgtaa
     9421 gtgtaatcat tgtcagtgaa gacatcgatt tgtggaagag cattgaaggc gataggataa
     9481 tgtttcttgt caccgcctga aggtaagatt tccgcatgca aatcacgtgg tttcactcca
     9541 tcattcaaga cctcacgaag ttcacgttgt gtctcaagaa ttgctcccat accagcacct
     9601 gaaacggctt gataagttga aacaatgata cggtccaagc cccatttttg gcgaaccggt
     9661 tcaagagcca ccatcatttg gattgttgaa cagttagggc aggcaatgat tccgttgtgg
     9721 gcatcaagtg catgagcatt gacctctgga acaaccaaag gaacatctgg attttgacgg
     9781 aaataagatg tattatccac tactaccacg ccagctttta ctgcgtatgg tgcatactta
     9841 gctgatgtcg aaccacctgc tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca
     9901 gtcgtttctt caatcgtaat atcttgatct ttaaatttca atgacttacc tgctgaacgt
     9961 gcagaagcaa ggtaacggat tttatcgatt ggaagtgttg attcttccaa catttttatc
    10021 atctgagcac cgacagcacc tgtcgcgccg actacagcaa ctgtatatcc cataaataac
    10081 ctctttcgga attttctaaa aatttctata atagaagtat tatactactt tttccatgaa
    10141 ttgcaaagct ttttcatcat tttttggaaa ataaaaatcc cagtcgctag actagggatt
    10201 aagaggcatc ttcatgtgat gagcaggttc acacaactca tcaaggtccg ctcctgcgtt
    10261 atgacctcct tatgctcaat agtagcccga agactaccta tcgactcatc gcatctacta
    10321 ttctactaaa gagaatgact ttggtcaaca gacgaaactc tttatactct tcgaaaatct
    10381 cttcaaactt cgtcagcgtc gccttgccgt atgtatggtt actgacttcg tcagtttcat
    10441 ctacaacctc aaaaacatgt tttaagctga cttcgtcagt tctatctaca acctcaaagc
    10501 agtgctttga gcaacctgcg gctagtttcc tagtttactc tttgattttc attgagtatt
    10561 agttttattt acacaggtgc ataagaaata tattggaaaa attgggggca gacataacaa
    10621 aaacccttgt aaatcaaggg cttttctgtc tatttaatgc taattgccgg gattgaaccg
    10681 gcgacctcat ccttaccatg gatgcgctct gccaactgag ctaaatcagc ttacttaaga
    10741 agtatactat attcagaaaa acttgtcaag tttccttaga aattttccat aggaaaaagc
    10801 caggtaagaa ctacctagct tatcttcttc tatttactta aatcaattcg acgaccaatt
    10861 ttaccaataa taatcgctcc aataatcaat gaagcaaatt caccgattcc tgttgtaaac
    10921 caagtaagga agaatggtaa ttctgctaca atatttaact ctgcagcgat agtaaacatg
    10981 gaaattgaaa agaggattga aaagaagaaa tgatcttttc gaatcaatcc gttaaagagg
    11041 taatccttgc tatattttgc aaaaagccaa acacctaaac tgaggaatac taaggttgaa
    11101 ccaccaccaa caaagacatc tagcagtccg aagctaaaga aattagcaat catacaaccg
    11161 atggtaactc cgatgatgta cttaggattg taaaaagcca taaagttcat catttctgaa
    11221 atacgaaact gataagcacc atagctgatg gcatttagag gcggtgtgac agtcaaaacg
    11281 acgtagatag cagcgacgat tgcaatatct gcaacatcac gaatagttaa ttttttcatc
    11341 ttttctcctt tggcggttgc ccgcgtgtaa tatgcttggt gaaagaagct aagcaccaag
    11401 ggttgcttta ttcaacccta ctagtatagc acaatagcct gctttatgct atacttaaca
    11461 catgaaaatt cctattcaaa aattttttaa caatgaaatc ttagcctatc tcttttttgg
    11521 ccttgcgaca actctagttt cgattctctc acgactagtc atttatcaac taagtcatca
    11581 ggaactcctg gctactgccc tagcaaatat tatcggtatc ctatttgcct ttatcacaaa
    11641 tgatacgatt gtatttaagc aaaaaaagaa aaatagactt atccgtttag tgaaattttc
    11701 tcttgctcgc ctttctactt ttctgttaga cttgttttta acttttctct ttgtaaccca
    11761 atttcctcac atcatagggc aattcgtaac tgaaaacatt gataagataa atgctattga
    11821 aacaataatt gcacaaatac tcattattat catcaattat atcttgagca aaatctatat
    11881 ttttagaaaa taatgctcca tttatgagcc ttttaattgc cttctataat gatttaggat
    11941 acaatgaaac acgaaacatt gaaaggaaaa cagtatgtta aaaaatctaa aatcgttctt
    12001 gcttcgagga aatgttattg accttgctgt cggtgttgta attgcctctg cttttggtgc
    12061 tatcgttact tcacttgtaa acgacattat cactcctctt attttaaatc ccgctttgaa
    12121 agctgctaaa gttgaacgta tcgctcaact ttcttggcat ggagtcggct atggtaactt
    12181 cttaagtgct attatcaatt ttatctttgt gggtaccgcc ctcttcttta ttatcaaggg
    12241 cattgaaaaa gcacagaaac tgactggcat aaaggaagaa aaaactgccg aaaaaaaacc
    12301 aaccgaattg gaagtccttc aagaaataaa agctctcctt gagaaaaaat aatcgattaa
    12361 aaggatctag cgcaaagcta aatccttttt tctttactct ttgggtaact tgcctgcttt
    12421 ttcaagcatt tttttgataa gataaggcat cttaacattc tcccgccctt ttttctcaat
    12481 cagttttttc acaaattctg gcatttgtaa atcttcagat tcagccaaaa tgtttttcgt
    12541 ctcgtctgaa ggaactaact catcaaaggt ctcttcttct ggtagaaatt ccttaaactc
    12601 ttgattttca ttgactctaa ttgtattgac caaagcatca atcaaacgag aatctgtatt
    12661 tggcattggt ggacgatggt agtttacccc aaattcctga cataagtcat aacattccac
    12721 atcattgtca aacaagacct caatatgctc actgatgaaa ctaataggta caaaaatata
    12781 atggtctgga tgttctgtct gttctctgag atactccaaa acatctggtt taatccatgg
    12841 aataccaata tcactctcac tctgccaagt gttggtatat tgttctgaac tcaagcccag
    12901 tttttcagcg actagcttgc tattttcgaa aatttggtct atataaggat caccaaagtc
    12961 caaggcaaaa ataggcacac tatgggctga aaagatgact ttaaagctgt cttgctttac
    13021 ttcttcttct aaaatcttag caatttcatc tgcccaatag tttaagagcg cttcttcctg
    13081 ataccagtcc ttaatgacca aaaattgaat ttgtttgctt tctaaaaatt tttcatagcc
    13141 catgacagag tagaaagaat aatggggctc caaaatcaag caaatacact gttcaattcc
    13201 gtctgcttcc atttgaccga tcacatctgg aataaaggga ctggaaaact tattagcaaa
    13261 gtagacactg tattcattcc ccagcctatc ttctaccaag gcaacctctt gacgggtaat
    13321 tttttgcaga ggcgtgcctc caattcgtac ataattatca tagagagtct gaatctcgtg
    13381 gtcttggggt ctcaccccac gacgaatatt tgtgaaaaaa tcagctacac cttcaaaggt
    13441 aatctcttct ggtgaaccga aggtcatcat taaaattgct tttttcatga ctgcttcctt
    13501 gtgatgtttt tatcaagttt attttatcat taattcatcg ataagtaaac gctaacatag
    13561 ggacattctc aatcttctgt cttttgtttt tctcttcttt ctatgataca atggaaaaaa
    13621 taaattcaaa aggagttttt ttatgactta tccaaatctc ttggaccgct tcttaaccta
    13681 cgttaaggtc aacacgcgct ctgatgaaca ctctactact actccaagta cacagagtca
    13741 ggttgacttc gcaacaaatc tcctaattcc tgaaatgaaa cgtgttggac tgcaaaatgt
    13801 ttactatcta ccgaatggtt ttgctattgg aaccttgcca gccaacgatc cgtctttaac
    13861 acgtaagatt ggttttatat cgcacatgga tactgctgat tttaatgctg aaggagtcaa
    13921 tccacaggta attgaaaact acgatggtgg tgtgattgaa ctagggaatt ctggtttcaa
    13981 actcgatcca gccgacttca agagtcttga aaaatatcca ggacaaacgc tcatcacaac
    14041 agatggaaca accttgctag gtgctgatga caagtcagga attgctgaaa ttatgacagc
    14101 cattgaatat ctaactgctc atcctgaaat taagcactgt gagattcgtg ttggttttgg
    14161 tccagatgaa gaaatcggtg ttggtgccaa taaatttgat gcagaagatt ttgatgtgga
    14221 ttttgcctac actgttgatg gtggtccact aggtgaactt cagtacgaga ctttctcagc
    14281 cgctggtgct gaattgcatt tccaaggccg taatgtccac cctggtactg ccaaagggca
    14341 gatggtcaat gcccttcagc tagcaattga ttttcataat caacttccag aaaatgaccg
    14401 acctgagtta actgaaggtt accaaggttt ttaccatcta atggatgtga caggtagtgt
    14461 tgaggaggcg cgtgcaagct acatcattcg tgattttgaa aaagatgcct ttgaagcgcg
    14521 taaagcatcc atgcaatcta tcgctgataa gatgaatgaa gaacttggga gcgaccgtgt
    14581 cactctcaac ttgacagacc agtactacaa tatgaaagaa gtcattgaaa aagatatgac
    14641 tccaattacc attgctaaag ccgttatgga agatctaggt atcacgccta ttatcgaacc
    14701 aatccggggt ggaacagacg gctctaagat ttcctttatg ggaatcccaa ctccgaatat
    14761 ctttgcaggt ggcgaaaata tgcacggacg ttttgaatac gttagccttc agactatgga
    14821 acgtgcagtt gataccatca ttggcatcgt agcttataaa ggctaaaaag acgaggtggc
    14881 tcagctactt cgcctttctt tttattctac tggtttttct tgatttccag tagttgtaga
    14941 agattctgtt gtttcatttt ctgaagttga ttcagcaggt ttagaatctc ttgtattgct
    15001 tggtttgttt tcgtcgctac cagtttcaat gttagattct gcagttgcgt ttggttggtt
    15061 ctcagcactg gtgttatcac catttgcttc agcatttctt gctggacttg tttcttcact
    15121 tgcgctagct tttgactgga tttgatgatt caaaactaga atagcttttg tcgattcaag
    15181 taaagctgtt ttgtctttac tcttagcaga aagttgatct aataatgcat ccaccttatc
    15241 aaagtccgca tcagatccat tattactttc taaataagag tgaagcgaca tgagaatatc
    15301 gtagagtttt tgatagagta caagtgtctg aggatcttgc tcagcatttt ccttttcttg
    15361 ttgaagggcg ctagcgatac gagtcaagac atcttttacc tgactgttta cttcatccaa
    15421 gtctgcatca gccttgtttg tggcagcttt tagattttct acttcttctg ccaaggattt
    15481 tctgattcct tcttcatgga tttgttccaa gagttgattt gccttgctca aaagactttc
    15541 tacttcttcc ttgctatctg tcgcagatta ttggttgcca tctaccatgt actcctaaaa
    15601 caggagagtt ataatccaag attacaaggc cttacagaaa taagaaatcc agataagaca
    15661 atgttcgtcc aagacgctat tcgcttcgca cagcagcacg gattcaatat gctttaattt
    15721 taaagtttag gtgtcaagac ctctttttag tgtgcccaaa atttagagaa gtaatcaatc
    15781 aactaacttt tatttttttc aaactttcag taaactgacc taaagctaac tcaatctgtc
    15841 tttgttcgat aggcttgtct ttgtagatgc ttctgctatc agctagaagt tgatctactt
    15901 ttgccaagac tgccttctca tcaaaagttc caggttgata gttggattgc agggatggaa
    15961 tcttgttttt caaagccgct tcatatccct tagtttgaac cttgatgtag tgattgtggt
    16021 cgccatgagg aatcacaaaa ccttctgaat cttcacttat aattcgattg gcatcaaaac
    16081 catgaccatc ttcttcctca tggtggacat gtagtgacgg attacttaat acagaactag
    16141 aagaacttcc tacctcttcc gtgttagagt gtgatggggg attgttaaga gatgacttag
    16201 gaatatagtg atagtgatcc ccatgtctta ctatataagc atcacctgta tctctgacaa
    16261 tatcattagg gttaaagaca taaccatcat ctactgcaga aacaccatta ttcggtgtca
    16321 ccggcaaaga ttgactgaga gctgtagtat tccctgataa ttatactttt gcgactgcta
    16381 attcacctgc cgacaagtca ctctcaggaa tgaaatgata gtgaccacca tgtggtacta
    16441 tagtagattg aaatagaata tgagcaaatt gataaggaga ttttaaagta atttctagca
    16501 atgatttaga aactatgatg tgctattcta aattcaactc actatatata accatcatcg
    16561 gtagtataac gtccctgtaa ttttgctaca gatacttctg cactagctcc tttatcgtct
    16621 ttaccatgtt cttgtttttg gcgattgatt tcatcttttg ttcgtacatt ttctgcatga
    16681 gcttgatctt taaggtaaac ataatacttt ccatctacct taataatata tcctccctta
    16741 acctaactga cgatatcttg atctttcggc tgatagttgg gggctttcat taatagctct
    16801 tcactaaaga gcgcatcaaa aggaacttta tcattatagt agtgataatg atcgccatga
    16861 gaagttacat aaccttgacc tgtaatctta ataacaattt gttttgcttg aattccttct
    16921 ttttgactaa cctagtctgg agtcaaattt tcagtcttct tagtgtcttt attactgttt
    16981 acatatgaaa cacgattttt atctgtattg gcctgttagc tatgttggtt cagagcataa
    17041 acacacagac ttaaggaaag gataacaaca gatccagctg ctatatattt ctttttaaat
    17101 ttcataatta cctcatttct ataattattt atatgatgtc ttcattatta aatgattaaa
    17161 taaattgatt aaccaattaa ttaactagta aatattccac ctctttttaa gttgtatgtc
    17221 aagagatttt atatattaat aataaaatga aattctccca aagtcagagt tttatttcta
    17281 acttttgaaa gaacttcatt tttgattcag actttttcta ctgctattcc ttacgctatg
    17341 agatcagata aattcttttt tatcacttct ccacttggca atcttaattc aatcgttcca
    17401 tccatattga atataacact atctaagcct aatccgtaac tagctgtaaa tttttctact
    17461 ttttcttgta caggatctac tgctggagct tcctctaacg ttgaattact agtactattc
    17521 ctagtttcag taagtttttc tttttctacc ttctcactag tctttggttc ttctaccttt
    17581 tcatcaagtt ttgagttttc ttgtgcttta ttccttttaa attgtggtag aatacttggt
    17641 ttatcagttt gattttcttt ttccaagata ggtacttcca caatataagt cgattgattg
    17701 tccaaataag catttgccat gaaggttaca ggaattttat ttccggccgt tctggttgtt
    17761 ccttggttta atttcggaat cggtaatttg atttcaccaa ctttatagtt attttctaaa
    17821 taagcatttc catgaaattc atcaaacact ctgactaaag catcagttcc tttaggcact
    17881 gcaaattgag ggttcactct taaataagta tcccctgcat ggaaaggata gaaaatcgtt
    17941 tgactggcca ttttgtaagc taaagaggtt gaaactgtaa atgtaccatc ataacttact
    18001 tctggataat cttttgaagc gatagtatac ttaaatgttt gtcctggtaa ataaggttga
    18061 tctaattcaa agtttgcaat attccctact ccttctccaa atactttacc agatactttc
    18121 tccaatactt ttccatctgg tgttattaat tttactagca tattgatacc taattttttc
    18181 tccaattcag gcggaaaact aaaagaaacg cgtttttgac cattggctag agtaaagttt
    18241 tgattattaa acgtactatt ttttaacaaa ttaacaacat tcgttaattc ttctccagta
    18301 taaactttat tcccttcttt tttagcaact ccttcttcgg gtttaaacag ttcatagtta
    18361 ctgtgagaat gaccaattcc aaccggttta tgttcatcaa tcggatctgc atgatggtga
    18421 tctccatgcg gataaataat cgcatttttt tctttattca cgacaatact ttcacgtttg
    18481 acaccatatt gtttcataat gccagcaatt ttttcttcga tttttttatc taaatctttc
    18541 atttctttgg cattacctga ataatcctgt tcatgagatt gcaaagaatc taatccatta
    18601 tgactagttt taacttcctc taaatgtttt tgagcagcct taatttgatc agctgtcaag
    18661 tccttcttga agaagtaatg attatgatta ccgtgactca tgataaatcc tgattcatct
    18721 tcagcgataa tacgattagc atcaaagctg gaatcatgtc cctcactgtg atggtgatcg
    18781 tgatcatcat aggctggagt tggtgtagca agcattccac ctttcaagtg atcctgcgca
    18841 gccttaattt gatcagctgt caagtccttc ttgaagaagt aatgattatg attaccgtga
    18901 ctcatgataa atcctgattc atcttcagca ataatacgat tagcatcaaa gccgtgccca
    18961 tcttcttcat gttcctcatg tgaaacatca ggattgactg gaagagatgg cgaaggtgtt
    19021 gttagaccat tatttggaag agtcggttgt ccaatttgat tcgacttagg aatatagtgg
    19081 aagtgattgc cgtgagggac aatataagca tcacccgtgt cctcaatgat atcagatgca
    19141 ttgaagatat acccatcatc cgttgtataa cgtccttgag ctctggcagc aactactgcc
    19201 ttatcgttag aatcgacacc gtgattacta ctatgttcct gtttctgacg tttaatctct
    19261 tcttttgtcc gaatattatc cgcatgggcc gcatctttaa ggtaaacata gtattttccg
    19321 tctaccttaa tcacatagcc acccttgatt tcattgacaa tgtctgaatc cttcaactga
    19381 taattcggat ctttcatgag aagttcttca ctgatgatgg catcataagg aaccttgcca
    19441 ttatagtaat gataatggtc tccatgtgag gtcacataac cttgagccgt aatcttgata
    19501 acaatttgtt ctgcgttgat cccctctttc ttactgactt catctggtgt caaattttct
    19561 gccttttgac cagcctgatc accatctata taagcaactc gattagactc tttcttagcc
    19621 tgaccagctt ggtgacgacc aagttcatag gaacaaacac ttagggcaag gactgccact
    19681 gaacctgcta gatatttttt attgattttc ataaatccct catttcaata aatgatgaag
    19741 ctttttctca acttctttta cttgattaaa tagttttcta aaccggttat ttaaccagta
    19801 aatggtttac tatttaaaat tacttttgtc aagtttctgt tacgtttttc taaaaaagag
    19861 aagcaacacg aaaggttact tctccataaa atatgctcca ttcattttac tactgtatag
    19921 gagtcggttt actttctttt aacaaagcaa agagactatc tacttctgct aaaatagtgt
    19981 tattgtcttt cgttccgaga agaagactgc tttgtagacc agccaatgtc tccatagcat
    20041 tttgttgaat acgagaatct gttactttcg caagtaaagc ctccgcctct gttatcttaa
    20101 cttcaataat agaacgctct acttgaggaa cttcagcttc ttctgtagta tcttcagctt
    20161 cttcctctgt ctcttccgta tcagtgcttg gtttataaag attatctgct gaaggattta
    20221 aacctgcgtg attctcttct tcatcagatt cagggcgagt tggctcactt acttcctcat
    20281 gttccttatt ttcatcaggt ttactgtctt ggtctgcctg atgcttacga acatggtcgc
    20341 tagcgttacc ccaaccatta tctgagtgag gacgttggtc aggatgttca acatagtatt
    20401 tcactgtcgc aaataaatct tctaaagtat acccttcagg agctgagtaa agcccttcat
    20461 caaaccatgc aaacttaagg ttatgatagt gatcaaagtg aggaattata aagtgaccat
    20521 tttgtacagc tacagtatac tgtaaatgat tcggtatttt ttctaatggt acctttttct
    20581 cagcttttac gcggttatag atagcttctg tccctgttgc ctctgttttt gcttctgttg
    20641 cttcagtaga atttggagct tgtaagcctt tttctttagc ataagcctga gctgctgctc
    20701 tttcagcttc agataagctg tcttttttaa tccagtggct atggttcaag tgtggagtga
    20761 cgtaggcatt tccttcatca ctttcaatat catgctcatc aaagatatag ccatcctctg
    20821 ttgtatattt acctgctaat ttcgctaatt taatttcatc gtctgtataa gcaatctgag
    20881 catttggttt gccaagtcgc tctggatgag taattggtgc taggaatgtc aataaatcat
    20941 ctaccaattt tactttatta gaagattcat tattcaagcg ttctgctaat ttgtctaagg
    21001 catggaaatc agaagtacgc cccttatttt cagacaaggc tttatgagcc tgggttaaca
    21061 gattgtaagc tttatcataa aattctcggt cacgagaagc gacactttct tttttagcaa
    21121 ctagagcatg tgtctcttga gttttcttag acaagtgatt ttcaatagca tcaatcttat
    21181 ccttagccaa gtctttagca aaaacatagt gactgacacc agcaatttcc acaacatagc
    21241 cttctccaac ttttctaaca acctgttcta ctgcaaaatc agtttgtttt ttctcagttg
    21301 atggttgaac ttgcggtttt ggtgctggtt tcaaataatg cattcctggc aagactgcac
    21361 cattttgtcc cttgatagct atcatacgag ccaatttttc ttccaaaggt gacatttgtg
    21421 aataagggat aaagtgataa tggtctccgt gcggtacagc aacaccattg gctgtacgat
    21481 atgctatttg tgccggatca aatactaggc catcagattc tacatggcgt tctgataagg
    21541 gtttagcata caattcacgt aaaaggcttg aaatgttttc cccttgattt tgatgataag
    21601 ttggagtgac agtcagattg tggttctctg acaatcttgg ttgagctgga tttgcattat
    21661 gactagaact tgaagaagga cgagatccct gcttcccatt ccaataggct tgggcagcag
    21721 ctaattcact ggcagacaaa tcactcttag gaatatagtg gaagtgattg ccgtgaggga
    21781 caatataagc atcacccgtg tcctcaatga tatcagatgc attgaagata tacccatcat
    21841 ccgttgtata acgtccttgg gatctggctg cagcaacagc attatctgct cttgagttat
    21901 gattatgact gcgttcctgc ttctgacgtt taatctcttc ttttgtccga atattgtccg
    21961 catgggccgc atctttaagg taaacatagt attttccgtc taccttaatc acatagccac
    22021 ccttgatttc attgacaatg tctgaatcct tcaactgata attcggatct ttcatgagaa
    22081 gttcttcact gatgatggca tcataaggaa ccttgccatt atagtaatga taatggtctc
    22141 catgtgaggt cacataacct tgatccgtaa tcttgataac aatttgttcg gcgttgatcc
    22201 cctctttctt actgacttca tctggtgtca aattttctgc cttttgacca gcttgatcac
    22261 catctatata agcaactcga ttagactctt tcttagcctg accagcttgg tgacgaccaa
    22321 gttcatagga acaaacactt agggcaagga ctgccactga acctgctaga tattttttat
    22381 tgaatttcat tctttcctca ctttaattct tctgctagaa tactcatatt ttcttcaaga
    22441 ttttctaaat aggtcttgtc attttgtggg tctgactcta aaggattcag agttttaaga
    22501 cccacacctg ttgatttgac aagagtttca gctacttttg aagaagcgtt actttctgta
    22561 aaaatcgttt taaccttata ggtcttaaca aattcctgaa tttctgttag ttgtcgtgga
    22621 cttggttctt gttcaggaga gatacctgca ataccaagtt gattgagtcc aaatctctta
    22681 gctaaataag aaaaggctgt atgttgtgtt acaaatgttt tctgagtcgc tttttcaaat
    22741 ttagactgga atttcttagt caattcctga gcttttttga taaaggcttg cgcatttttc
    22801 tggtaagttt ctttatgctc actatccacc tctgaaagtt tatcagcgat aatctgagct
    22861 tcttcgccag ctttttcagg atctagccaa gtgtgagggt catagagcgt tttttcatca
    22921 actccatccc ctgcttctac atcttctagc cctgggacac ggtctaaagt cattccctct
    22981 gaagcctcta agaccttcac tttagatttt tttagattgg gatctaaact tcctgcccaa
    23041 gattctagcg tatgagaatg gtaaacaaag acatctgcat catagatggc cgcgatgtca
    23101 tttgccgaag gttcaaagga gtgaatccca ctactcgact gaatcatccg aacatcattc
    23161 aagtcaccag aaacctcctt gaccatggca tagataggat aaaaactggt cacaattttc
    23221 atccctttcc cagtctggct ttctttttga ccacaagctc ccaagcatac aagaaagata
    23281 cttaacaaga ctaaaaataa attttgtttc ttcatgaaca actccttaac catttaatta
    23341 actagtaaac attctactcc taaaaattta atctgtcaag atatttttag aaaaaaattg
    23401 aaatttcttt cacatataaa aatctgctga gtttcaacaa ctcaacagac ttccacttta
    23461 ttcttctatg gttgaatgct tatagccata agtaaagtaa ataagacttc ctatcaacaa
    23521 agcaacgagg aaagcaatcc aggtttccat attatactgc aacatgaagg atagacaaat
    23581 gatgattgat aaaatgggta acagaggtac caatggtgtt ttaaattccc cagctttggg
    23641 cattcctttt tctttccgta agcgaatcag accataagcc agcatgatca agtaggctaa
    23701 ggtacaagta tttaagaagg ctgcaatact agctaatgga aacattcctg ctgctactgc
    23761 tgaagctaga cctgtcaaga tagtagcatt ttttggtacc ttgcttgttt ttgttaattc
    23821 tttaaaggca gcaggcatta acccgtcacg cgctaaactg taaatcatac gcgatagtgc
    23881 ataggtcatc gaaatacaaa ctgtaatcaa ggtcaagata gccactaatg acacatagtt
    23941 agctgcccaa ctaatcccaa cgctacgaag agcaaaggca acggcatcat cgacatttag
    24001 ttgactatag tgaaccacac cagtcaagac aagcgtcacc aaggcataga gaatggttac
    24061 gatagaaagt gataagacaa tccctctagg aatattcttt tgaggagtct tgacttcatc
    24121 tacagccata gagatggatt cgaagcctaa aaatccaaag aacatcaagg acgcaccagc
    24181 cataatacca gtactagcac catagatttg tccaaaacca taaggagcaa aattactcca
    24241 attatcaagt ttgatatgcc aaattcctac taaaacaaag agagctaaag ccgagaattt
    24301 cagaatgacc aaaattgaat taaagcgtaa ggctgcttta gcattgagta aaacaagcga
    24361 tgtcactaat gccaagacaa gaataggcaa taaatcaaca aatgttcctg cctgaggatt
    24421 aaaggtacca tttaaagcct gaggaagggc tatcccgtat tgagagagca agcctttaaa
    24481 ataagctgcc caacccgaag ccacacctga tatggctgtc atgaactcca tcatggttaa
    24541 ccagccagcc aaccaagctg gaaattctcc taaaatagca tagagataac tgtaggcacc
    24601 acctgtagcg ggtactcgcg aggcaaattc tgcaaaaaat agtgctgata atcccacaca
    24661 taaggcagaa ataacgattg aaatcactag ggctggacct gctagagttg cggctgcagt
    24721 acctgtgatt gtaaagacac ctgtccctac catggctccg atacccagca aaatcaaatc
    24781 ccataacttc aaatgcctgt gcatctcagt tttatccaaa cttacattct ttgttctaaa
    24841 tatattcatc tttgacctcc aaaataaaat gatgattcta ttttaccata aatataggag
    24901 atatgtgaat atttataaaa tgtttttcta aaaaaatctg actacatctt gtaatcagat
    24961 tttatcgatt ctagttcatt tctttaaatg ctgcttctgc atccgcgttg ctgataacac
    25021 caaattgaat ctttccaatc ttttcttgac tatcaatcag gtattctgta ggaatgcttc
    25081 gaatttgata agcttggaag gttgttgctt tggtatcata aagaactggg atatccttat
    25141 aaccttgatc ttggaaccat tgtgggaatt gttcgacagt tttttcacct tgaattcctg
    25201 gtgcaatgac agtaagaatt tcaaaatcgc gatctggttt tgcagctaat tccatcaact
    25261 caggcatact tttcttacat ggaccacacc atgaagccca aaacttcaag tagacttttt
    25321 tacccttaaa atcagataac ttcacttctt tgccatccat ggattgcaat gtgaagtctg
    25381 gagcttcttt tccaacagca atttgttgta caggcgtttg ttgctgttgt tttggggatt
    25441 gttctggtgc ttgagtcttt ttagcctctt cttcaccaca ggccatcagt acaactaatg
    25501 acaagaggct taaaccagca aacattactt ttttcatttg ttctccttta ttcaaaaatt
    25561 cctgctagaa cattgacttg tcctaatagt aacaaaattc ccattaaaat aatgaggaaa
    25621 ccaccaattt tcttcagtag catcatatga cgcttgagtt tactaaaata aggcatcact
    25681 atgcctgaag ctagagccaa gaccaagaaa ggaatggcca tgcccagagt gtaaataaga
    25741 gtatagatag ctccttgcca ggcgccattg cctccagaag ccgcaagtgc taagacagaa
    25801 cttaaaaccg gaccaataca aggcgtccaa ccaaagctaa aggtaatacc aagtaaaaaa
    25861 actgaccaat aacgattaga atctgatttt ttaaaggtaa aacttttttg aacttctaat
    25921 ttcttcaaat gaaaaatttc catctggtga agacccaaaa tgataataat aactcccatg
    25981 acatatcgaa accaatttgc atagagaaca tgaccaaagt aaccagcacc aaagcctaga
    26041 ataaagaaaa tgagagagat acctgcgata aagcaaagtg ttcgaatcaa gcctaaccag
    26101 agaacctttc tcccaaacaa agaaaagctt tttgcacttt cttgatcatc caataaaatc
    26161 ccagcataga ctggcagaag aggaaaaata caaggagaaa aaaaggataa aacacctgct
    26221 agaaaaacag agattgaaaa tactatcgtt tccaataaag aaccaacttt cttaatcatt
    26281 ctaatcctat tttactatat tcaattttat ttgtaagctt tctgctacgc aaattcgtct
    26341 tgaacactat tggaccaatc ttttcttttg ctagtcaagg cggatcttat ccccaaaaat
    26401 agccaaaaag caacgacaag gattactcgt cgctgctttt gtgaacggaa atgtctttta
    26461 ggtctgacgt ttcagaaatc acattttact tgagtttagc aaggattgat ttaagctcct
    26521 ctactagttt agcttctgtc tctgctgagc cattttcttc ttttacgaaa tcaagggttt
    26581 cttggagaag gttttgggct ttggcaagga cttttttatc cgctttttct gcatctagtt
    26641 gtccgagaat cttggtcaat tccgtactta attgctggat ttctgactct ttcttacggc
    26701 gaaccaacca gaaggcaatc acgcctagga ggacaagtag actgaccaca atcactcctg
    26761 gtggaactga ggttgtttca gtcatcttag ctgaatcctt actatcttcc gttccttgtt
    26821 tggcatcctt cttgtcctgt gcaggcttgc tgtcgctagc atttgctggc acatctttga
    26881 gagagttcaa ggcagccttc acagactcta ctgcagtatg cagaccttac tctgtcaagg
    26941 cacgaagttc agaacttgtc aacttgctct tgagctggag cttgcgtgct cgttgagcta
    27001 gccgaagcgc ttgctaccac tctaggatct tgagtcggag ctgagcttgg agctgggaca
    27061 ggatttgcag gttgactagg agcagttatg gtatattgaa actagaatag tacatattga
    27121 cttctaaaac attgctaaaa atttatttga ttatcctgat tattttgtcc tatttctgtt
    27181 tcattttatt ataattgaga cggttgagca cttggactag atggagttgt tggtgtctct
    27241 gtgtctcctt ggtctggctg agtaggggta gaaggttgcg gttgaggcgt agaaagtgga
    27301 cgtgaagttg gttgtggatt gatgttattg atagcatcga ttcctaccac ttttgcctgt
    27361 tctacatcct tatttgttac gcccttgtcc accgcaatct tagcatcgtt cgcctcttga
    27421 tctacctgtt gcaatgctct tgacttatcc tcaattgtca aatcaaaacg attcgaaatt
    27481 tctgttttct tagcctctgc tgccgcattg atggcttctt ttgcttcagc tttcttagta
    27541 gttcttggta acgtgacttt tcctatgtta gtaattccat tattcttcgc tgtgttcaac
    27601 gttgtttcat cttgagcgtt ttctatattt tgaatagctt tatcttttac tgttttcgct
    27661 aatcctttca cttctatttt tttcattagt taaagaatta tccttatcta tattagaagt
    27721 tttcgttgaa aatgcttgtt ctacttcatt tttcgcccca tctttatcta atgttggagt
    27781 tgttggagtt ggtattgtta ccgcatcact catgtctgat gtagatcttt ctacattaat
    27841 atttccacca taagtagctg gtatatattc tctgtctcta gctatgtttc tagtagttat
    27901 tttatctcca gcttgtaatg cttcatccgg tgtccaacta gcagttccgt ttacagcagt
    27961 aattgttgct ttttagtgtt atttaaataa aattcaacaa tagaatcatt agaatttctc
    28021 gctgttgatt taactatcac tcgtttacct gcaacatttt ccaaattttc taccgtagac
    28081 ttcctgcaaa actagaatcc tagttcatga ttggtaatac cagcaatcaa attcattcgt
    28141 aatccgaagc gtttacgatg atttcgatag gttgttgaaa acattttaaa cgtttttact
    28201 ttggcaaaga tgttttcaac cttgcttctc tccttagata gcgcatggtt acaggcttta
    28261 tcttcaactg
//
LOCUS       DAVFJR010000028        24538 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVFJR010000028 DAVFJR010000000
VERSION     DAVFJR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.029"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(224..2482)
                     /locus_tag="VU722_001456"
     CDS             complement(224..2482)
                     /locus_tag="VU722_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1772405.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGFQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILRGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPIGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADINKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2706..2936)
                     /locus_tag="VU722_001457"
     CDS             complement(2706..2936)
                     /locus_tag="VU722_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEU1772406.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVSYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3126..3809
                     /locus_tag="VU722_001458"
     CDS             3126..3809
                     /locus_tag="VU722_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1772407.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQVGILGVDLSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTIYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KRMGQGDKK"
     gene            3809..4543
                     /locus_tag="VU722_001459"
     CDS             3809..4543
                     /locus_tag="VU722_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1772408.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESKAVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4697..5554
                     /locus_tag="VU722_001460"
     CDS             4697..5554
                     /locus_tag="VU722_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU1772409.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTEKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALWTLDRK"
     gene            5696..6568
                     /locus_tag="VU722_001461"
     CDS             5696..6568
                     /locus_tag="VU722_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU1772410.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLPSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6850..7533
                     /gene="rpiA"
                     /locus_tag="VU722_001462"
     CDS             6850..7533
                     /gene="rpiA"
                     /locus_tag="VU722_001462"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU1772411.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7547..8758
                     /locus_tag="VU722_001463"
     CDS             7547..8758
                     /locus_tag="VU722_001463"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU1772412.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8760..9302
                     /locus_tag="VU722_001464"
     CDS             8760..9302
                     /locus_tag="VU722_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU1772413.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVENLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPLY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9318..10127
                     /locus_tag="VU722_001465"
     CDS             9318..10127
                     /locus_tag="VU722_001465"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU1772414.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHAGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10624..12231
                     /locus_tag="VU722_001466"
                     /pseudo
     CDS             10624..12231
                     /locus_tag="VU722_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664829.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            12256..12768
                     /locus_tag="VU722_001467"
     CDS             12256..12768
                     /locus_tag="VU722_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU1772415.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13426..14136
                     /gene="deoD"
                     /locus_tag="VU722_001468"
     CDS             13426..14136
                     /gene="deoD"
                     /locus_tag="VU722_001468"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU1772416.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14159..14683)
                     /locus_tag="VU722_001469"
     CDS             complement(14159..14683)
                     /locus_tag="VU722_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU1772417.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14736..14972)
                     /locus_tag="VU722_001470"
     CDS             complement(14736..14972)
                     /locus_tag="VU722_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU1772418.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(15040..15960)
                     /locus_tag="VU722_001471"
     CDS             complement(15040..15960)
                     /locus_tag="VU722_001471"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU1772419.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGSLNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWSSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16150..16553
                     /locus_tag="VU722_001472"
                     /pseudo
     CDS             16150..16553
                     /locus_tag="VU722_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16769..17350
                     /locus_tag="VU722_001473"
     CDS             16769..17350
                     /locus_tag="VU722_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1772420.1"
                     /translation="MYYAENPDTAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17347..18624
                     /locus_tag="VU722_001474"
     CDS             17347..18624
                     /locus_tag="VU722_001474"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU1772421.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTIAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18642..19304
                     /gene="deoC"
                     /locus_tag="VU722_001475"
     CDS             18642..19304
                     /gene="deoC"
                     /locus_tag="VU722_001475"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU1772422.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGAGEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19291..19680
                     /locus_tag="VU722_001476"
     CDS             19291..19680
                     /locus_tag="VU722_001476"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU1772423.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19770..20822
                     /locus_tag="VU722_001477"
     CDS             19770..20822
                     /locus_tag="VU722_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU1772424.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20966..22501
                     /locus_tag="VU722_001478"
     CDS             20966..22501
                     /locus_tag="VU722_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772425.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVVENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEITGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RVASELVPAAALSGGNQQKAIIAREIDRVPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22494..23552
                     /locus_tag="VU722_001479"
     CDS             22494..23552
                     /locus_tag="VU722_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772426.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGLVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLSELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGASLAV
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23555..24511
                     /locus_tag="VU722_001480"
     CDS             23555..24511
                     /locus_tag="VU722_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772427.1"
                     /translation="MSITTLLTLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGCLFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYI
                     AIAFSFLAWFILFKTRFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPTVYLQIAPYVLTTLVSAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7143 a         4439 c         5583 g         7373 t
ORIGIN      
        1 tgctcttgtt tcaattgact atagcagatt gaaataagat gagaacaaat cgattgggaa
       61 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttca gattcagtct
      121 actatatatc ataatggaca aagggtaagc tgtcaagaaa ttacagttat tttagtaaaa
      181 aagaagcaga aaaatttcat tttctactcc ttttctatag gatttatttt tctttttcag
      241 aacttttaac ttcagctttt ttggcagatt taatctgaat gtttcccttg ctagtcataa
      301 ctgctttgag atctttttcg cttggatttt caaggtagta gtcagtgatt gtgtcctcaa
      361 tatagtcttg aatagtccga cgaagtgggc gtgctcccat ttttggatca taacctaggt
      421 caaccaactt ttccttgacc ttgtcagtta catccaaacg aatgttgttg ctagagaggc
      481 gcttgttaat atctgctagc atgagctcga caatctgaag gaggttatcc ttgctgagag
      541 ccttaaattc gataatgcca tcaaaacggt tcataaactc tgggctaaag aagttaccga
      601 gttcaccgag gacagaattg gtacgtcctt ctctagcagc accaaatcca acgctagctt
      661 cggtctttcc tgtacctgca tttgaggtca tgataatgat ggcatccttg aagctaacgg
      721 tgcgtccttg cccgtctgtc aaacgaccat cgtccaagac ttgaagaaac atgtgcataa
      781 catctgggtg agctttttcc acttcatcga gaaggatgag agaatatgga ttgtggcgaa
      841 ctttttcagt taattgacca gcctcatcat agccaacata acctggagga gcgccgacca
      901 acttagccac actatgtttt tccatgtatt cactcatatc aaagcgaatc atactatcag
      961 cagaaccaaa aagttcgata gccagttgtt tggaaagttc tgtcttaccg acaccagttg
     1021 gcccaacgaa gaggaagctt ccgattgggc ggttaggggt accaagtccg acacgattac
     1081 ggcgaatagc cttggcaatc ttatcgactg catcatcttg gccaataaca tgagacttga
     1141 gatcttcggc tagatggatg agttgagatt gttctttctc tttcaaatca ccaataggga
     1201 tattggtttt ctgctcgata atgtgctcaa tagttttctc gctgatgata ggagtatcct
     1261 ggtctgtgat ctttttcttt tgcatttcct tatacttggc aatctggtcg cggaagtagg
     1321 ccgccttctc aaaatcttct tctcgtgtag cttgagactt gagattttca gcctcaatca
     1381 agcgctgatc aattacttta ggatccacaa aattcaaggt caagttcatc ttagaaccag
     1441 cttcatctag gaggtcaatg gccttgtcag gcaagaagcg atcttggatg tagcgattgg
     1501 aaagagttgc agctgcttca atcgcagcat cggtatattg aacgtggtgg taatcttcgt
     1561 atttcttttg aatccctctg agaatagtga ttgtttcgtc caccgttggt tcatcgactt
     1621 taacaggctg catacgacgc tcgagggcag catccttttc aatgatacgg tattcattga
     1681 gggtagtagc accgactagt tgcagttctc cacgagcaag ggctggcttg aggatatttc
     1741 ctgcgtccat attaccatca ctcgcagaac cagcaccaac aatttcatgg atttcatcga
     1801 taaagaggat gatgtcttca cgtttgcgaa tttcttccat gagtttttgc atgcgttctt
     1861 caaattgtcc tcgaatcccc gttccttgaa ctaagctaac cacatccaga cggatgactt
     1921 gtttaccttg gagtttatgt ggcacatcgc catcgacaat tttctgagct agaccttcga
     1981 caacggccgt ttttccgaca ccaggttcac cgataaggac aggattattc ttggttctac
     2041 gattgagaat ctcgatgaca cggataatct catcgtcgcg cccaataacg gggtcaatgt
     2101 ctccacgacg ggcaatttca gttacattaa taccaaattc ttccagcagg cctttttctt
     2161 ggctaggtgg cggagtttga gcagatccac gattttggaa accataaccg ccgtttccac
     2221 cgtaacctcc acctgattgg gttgggggaa taggaggagt attgctagaa ggtctgaaat
     2281 tgtttagatc attgaagaaa tcaccaaagg gatcgaagtc acgattgttc agatccgtca
     2341 tacctttgaa gaggctattg ttaggatctg ttttgataat cttatagcag ttttgacaga
     2401 ggtcaatttg tttttgtttt ccattgagat tggtgtaaag atgaattgtt gagtcgttaa
     2461 ttttacagtt ttgacaaagc atacatctac ctcatttctt tctttagcct gacttgttta
     2521 aaggtcaaaa atagtcaaat tctatactct cattataaca ggattggggt gtaaagcaag
     2581 taaaaagatt gaagctttga gaagttgtta caatgaaaat ttttgtgaat ttggactata
     2641 aaaaaatcct atttgtgaga caaaaaggat tttacttaga catgcaggga caatcccagc
     2701 ttgttttagt agagaagttc gtaaatttcc attgcgatta agtcaatgct atcaaacgta
     2761 tacgtttcgc gatcttctac gtcacgaagg gtaaagattg ggccgttttc ttcgtcgtgg
     2821 ctgtacgaaa cttctgcaac aacaactcct tcgcgttcaa aattacgttt taaatttccg
     2881 ccatcgtttg ccattgcttc aaggcggttg atgattctaa ccaaatgtga ttccattttg
     2941 attctccttc atttcttatc gttactattt taccataaag gaggccaatt tgactagaaa
     3001 aaactaagat ttcttgctaa ttctgctagt ttaaagattt ttaaataaat tggataaaag
     3061 atttgaattt taattcaaaa catgttataa tcatacagta ttctatttta gaaagcagtg
     3121 tgactatgaa tttttctttt ttacctaagt atttacctta ttttaactat ggggctgttg
     3181 tgacgattct tatttctatc tgtgttatct ttttgggaac tattttgggt gttgtcttgg
     3241 cttttgggca acgttcaaag tttaaaccgc ttgtttggtt ggccaacttg tacgtttgga
     3301 ttttccgtgg gacaccgatg atggttcaaa ttatgattgc ctttgctctt atgcatatca
     3361 atgctccgac tattcaggtt ggaattttag gtgttgatct ttctcgtctg attccaggga
     3421 ttttgattat ctctatgaac agtggtgctt atgtttctga gactgttcgt gccggaatca
     3481 atgcagttcc taaggggcag ttagaggcgg cttattcttt agggattcgt cctaaaaatg
     3541 ctatgcgcta tgtaatttta ccacaagcta tcaaaaatat cttgccagct ttggggaacg
     3601 aatttatcac cattatcaag gacagctccc tcttatcagc tatcggtgtt atggagttgt
     3661 ggaacggggc tacaacagtt tctacaacaa tctatctacc tttaacacca cttttatttg
     3721 cagcttttta ttacttgatt atgacttcta ttttgacagt agccttgaaa gcttttgaaa
     3781 aacgtatggg acaaggagat aagaaataat gacagaaacc ttgataaaaa ttgaaaattt
     3841 acataaatca tttggaaaga atgaagtatt gaagggcatc aacctcgaga ttaaaagagg
     3901 agaagttgtc gttatcatcg gtccttcagg gagcgggaaa tctaccttgc ttcgctctat
     3961 gaatttgttg gaagaagcga ccaagggtaa ggttatcttt gagggagtcg atattacgga
     4021 caagaagaat gacctctttg ccatgcgtga gaagatgggc atggttttcc aacaatttaa
     4081 cctctttcct aatatgactg tgatggaaaa tatcaccttg tcacctatca agaccaaagg
     4141 tgagagcaag gctgttgctg agaagagagc ccaagagctt ttggaaaaag ttggtttgcc
     4201 agataaggca gatgcttatc cacagagttt gtcaggtggc cagcaacaac ggattgccat
     4261 tgcgcgtggg ttggccatgg aacctgatgt tttgctcttt gacgagccaa cttcagcact
     4321 agatcctgag atggttggag aagttctggc tgttatgcaa gatctagcca agtcaggaat
     4381 gaccatggtt atcgtaacac atgagatggg atttgcccgt gaggtggcag atcgtgtcat
     4441 ctttatggca gacggtgtgg ttgttgaaga cggaacacca gaacagattt ttgaacaaac
     4501 ccaagaacaa cggactaaag acttcttgag taaggtttta taatctattt taaaatttca
     4561 agacaagatt agtgaaaagc tcaaccagag ctttttctta tagtttgaaa ctataggatt
     4621 gcctaggaaa gaagtgttag agggtgctgg cagtttttgg tataatggaa gatatttgaa
     4681 agaaaagaga agtgatatga cacagattat tgatggaaaa gctttagcgg ccaaattgca
     4741 ggggcagttg gctgaaaaga ctgaaaaatt aaaggaagaa acaggtctag tgcctggttt
     4801 ggtagtgatt ttggttgggg acaatccagc cagccaagtc tacgttcgca acaaggagag
     4861 gtcagctctt gcagctggtt tccgtagcga agtagtgcga gttccagaga ccattacgca
     4921 agaggaattg ttagacctga ttgctaaata taatcaggat cctgcttggc atgggatttt
     4981 ggtccagttg ccattaccaa aacacattga tgaagaagcg gttctattgg ctattgaccc
     5041 agaaaaggat gtggatggtt tccatcccct aaacatgggg cgtctctggt ctggtcatcc
     5101 agtcatgatt ccatcaacac ctgcaggaat tatggaaatg tttcatgaat atgggattga
     5161 cttggaaggt aaaaatgcgg tcgtcatcgg ccgctccaat atcgttggaa agcccatggc
     5221 ccagcttctt ttggccaaaa atgcgacagt aaccttgact cactcacgga ctcataatct
     5281 tgccaaggtg gctgctaagg cagatattct tgtggttgca attggtcgtg ctaagtttgt
     5341 gactgctgac tttgtgaaac caggtgcggt agtcattgac gttggaatga accgcgatga
     5401 aaatggtaag ctctgtgggg atgtggatta tgaggcggtt gccccacttg ctagccatat
     5461 tacgccagtt cctggaggtg taggtcctat gaccattact atgctgatgg agcaaactta
     5521 tcaggcggca ctttggacat tggatagaaa ataagagaaa cattcgatta atagagtgta
     5581 ttttctatag ctatatctaa aatggcagaa atgaatatta aattttagat ataagattac
     5641 aaaaggaggt ctgcgcctcc tttttgttgt ataataaaag tgagaggaaa aaaggatgaa
     5701 agtgattaat caaaccttac tagaaaaagt tattattgaa cgttctcgtt caagtcataa
     5761 aggagattat ggtcgtctgc tgctgcttgg tggtacttat ccttatggag gtgccatcat
     5821 catggctgct ttagcagctg taaaaagcgg tgcaggattg gtgaccgttg gaacggacag
     5881 ggaaaatatc ccggctctgc acagccattt acctgagcct atggcctttt ctcttcaaga
     5941 ccagcaattg ttaaaagagc aattggagaa ggcagaagtt gtcttgctgg ggcctggttt
     6001 acgagacgat gcttctggag aaaatctagt aaaacaggtc tttgttaatt taagccaaaa
     6061 tcagattttg attgtagacg gaggtgcctt gaccattctt gctaggacaa gtttgtcatt
     6121 tccctcaagc cagcttatcc taactcctca ccaaaaagaa tgggaaaaat tatctggaat
     6181 tacgattgaa aagcaaaagg aagatgcaac ggctagtgtt ctgccttctt tccctcaagg
     6241 aacaattttg gtggagaaag gcccagctac tcgtatttgg gaagttggcc aatctgatta
     6301 ttaccagtta caggttggtg gtccttatca ggcgactggg ggaatgggag atactctggc
     6361 tgggatgatc gcaggatttg taggccaatt ccgacaggcc agtctctacg agcgtgtggc
     6421 agtagcgacc catcttcatt cagccatagc tcaagaacta tctcaagaaa attatgtggt
     6481 cttaccgacg gaaatcagca ggtatcttcc caaaataatg aaaattattt gtcaacaaga
     6541 gagggtaagc aaagataaac ttgtttaaaa tagacagata aatctacttc cttctcttaa
     6601 tttatgattc ttgaaatgca cctgctttaa ggctaaacta gacgtatcaa agttaagagt
     6661 ttgtttttgt aactggaaag agatgaacaa atcaaataca taaaagataa actcattttt
     6721 attcgtttgg taaaaataaa atacatattt ttaaagaaag attgatgaaa aatgtagatt
     6781 tgatgttttt acttgaataa aaagcggttt catagtaaaa taagaactga gaatgatgga
     6841 ggtaaatcgg tggaaaatct gaagaaaatg gcaggtatca aggctgctga gttcgtgagc
     6901 gatggaatgg tcgttggact tggaacaggc tcgactgcct attattttgt cgaagaaatc
     6961 ggtcgtcgta tcaaggaaga aggattgcag attacagctg taacaacttc tagtgtgacc
     7021 actaaacagg cagaaggcct taatatcccg ctcaagtcta ttgaccaagt agactttgtc
     7081 gatgtgacgg ttgatggcgc ggatgaagtg gatagtcagt ttaatggaat taaaggcggt
     7141 ggtggtgccc ttctcatgga aaaggtggtc gcaacaccat caaaagaata catttgggtg
     7201 gtggatgaaa gcaagctggt cgaaaaacta ggtgctttta aattgccagt agaagtggtt
     7261 cagtatggtg cagagcaggt ctttcgtcat tttgaacgag ctggctacaa accaagtttc
     7321 cgtgaaaaag acggccaacg ttttgtgacg gatatgcaga attttatcat tgacctcgcc
     7381 ttggatgtca ttgaaaatcc aattgctttt ggacaagaat tggaccatgt cgttggtgtt
     7441 gtggagcatg gtttattcaa tcaaatggtg gataaggtaa tcgttgctgg acgagatgga
     7501 gttcagattt caacttcaaa aaaaggaaaa tagaaggggg cataagatgt ctaaatttaa
     7561 tcgtattcat ttggtggtac tggattctgt aggaatcggt gcagcaccag atgctaataa
     7621 ctttgtcaat gcaggggttc cagatggagc ttctgacaca ctgggacaca tttcaaaaac
     7681 agttggtttg aatgtcccaa acatggctaa aataggtctt ggaaatattc ctcgtgaaac
     7741 tcctcttaag actgtagcag ctgaaagcaa tccaactgga tatgcaacaa aattagagga
     7801 agtatctctt ggtaaggata ctatgactgg acactgggaa atcatgggac tcaacattac
     7861 tgagcctttc gatactttct ggaacggatt cccagaagaa atcctgacaa aaatcgaaga
     7921 attctcagga cgcaaggtta ttcgtgaagc caacaaacct tattcaggaa cggctgttat
     7981 cgatgatttt ggaccacgtc agatggaaac tggagagttg attatctata cttcagctga
     8041 ccctgttttg cagattgctg cccacgaaga cattattcct ttggatgaat tgtaccgtat
     8101 ctgtgaatac gctcgttcga ttacccttga gcgtcctgcc cttcttggtc gcatcattgc
     8161 tcgcccttat gtaggtgaac caggtaactt cactcgtacg gcaaaccgtc gtgacttggc
     8221 tgtatctcca ttttccccaa ctgttttgga taaattgaat gaggctggta tcgatactta
     8281 tgctgtgggt aaaatcaacg atatctttaa cggtgctggt atcaaccatg acatgggtca
     8341 caacaagtca aatagtcatg gaattgatac actattgaag actatgggac ttgctgagtt
     8401 tgaaaaagga ttctcattca caaacctagt tgactttgat gccctttacg gccatcgtcg
     8461 taatgctcac ggttaccgtg attgcttgca tgagtttgat gaacgcttac ctgaaattat
     8521 cgcagctatg agagagaatg accttctctt gattactgcg gaccatggaa atgacccaac
     8581 gtatgcagga acggatcaca ctcgggaata tattccattg ttggcctata gccctgcctt
     8641 taaaggaaat ggtctcattc cagtaggaca ttttgcagat atttcagcga ctgttgccga
     8701 taactttggt gtggaaactg ctatgattgg ggaaagtttc ttagataaat tggtataaga
     8761 tgacgcgcta tgctttgctg gtgagaggta tcaatgttgg tggtaagaat aaggtcgtca
     8821 tggcggagct tcgtcaagaa ttgacaaact taggactgga aaaggttgag agctacatca
     8881 acagtggcaa tattttcttt acttcgatag attccaaagc ccaattggtt gaaaagctag
     8941 agactttctt tgcagtccat tatccattta ttcagagctt ttctttactg agtctagagg
     9001 actttgaggc ggaacttgaa aatctaccag cttggtggag cagagacttg gcacgaaaag
     9061 attttctctt ttacactgag ggtttggatg tggaccaagt catcgcgaca gttgaaaatt
     9121 tagagctgaa agatgaagtg ctttattttg gaaaacttgg gattttctgg gggaaatttt
     9181 ctgaagaatc ctattctaag actgcctatc ataagtactt gctgaaggtg cctttatacc
     9241 gccacattac tattcgtaat gctaaaacct ttgacaaaat tggtcaaatg ctaaaaaaat
     9301 aataaaggag acacacaatg acatttttaa acaaaatcca tgaaactgct actttcctga
     9361 aagaaaaggg aattgcagcc cctgagttcg gtctaatcct tgggtcagga cttggagaat
     9421 tggcagaaga aatcgaaaat ccagttgtag tagactatgc tgagattcca aactggggcc
     9481 gttcaacagt agtcggtcat gctggtaaat tggtatatgg tgaactggca ggtcgcaagg
     9541 tcttggctct tcaaggtcgt ttccatttct atgaagggaa tcctctggaa gtggtgactt
     9601 tcccagttcg tgtgatgaaa gttcttggat gtgaaggtgt tattgtaacc aatgcagctg
     9661 gcggtatcgg atttggtcct ggtaccttga tggctatctc agaccatatc aacatgacgg
     9721 ggcaaaatcc attgatgggt gaaaacttgg atgactttgg cccacgtttc ccagatatgt
     9781 ctagggccta cacaccagaa taccgtgcca ctgcccatga agtggctaaa aaacttaata
     9841 tcaagcttga tgaaggtgtc tatatcggag ttactggtcc gacttatgaa acaccagcag
     9901 aaattcgttc ctataagaca ctgggagcag atgcagttgg tatgtctacg gttcctgaag
     9961 ttatcgtggc agcccacgct ggcttgaaag ttctgggaat ttcatgtatc actaactttg
    10021 cggctggttt ccaagaagaa ctcaatcacg aagaagttgt agaagtgact gaacgtgtta
    10081 aaggtgattt caaaggcttg cttaaagcga ttcttgctga attgtaagaa aaaagattta
    10141 aaagggggag tgcctctgtt ttttcaggat tgactgccta tccggattaa agaagaaaca
    10201 gaggaatact atgagcttct tcctgctctt ataactgaaa gaagcggaag aataggtatg
    10261 tctgatctga tagccagcat tgtgaaagac aagattctag gatactagca ttagcttcct
    10321 agccaagcag actagtatga taaggagaga tgagaatgaa ttgactttct gaatttctca
    10381 gtcttatcat atatagcaca atgagatttc gcttgagtct gcttgtaaat aaacgaaaag
    10441 aaagataaga aataatgaaa attggtcaac gaattatgcg ctttggcata aaaaattaag
    10501 tatcggagtt gtatctgttg tagtcggctt tgatttctag ctccagctgg aatttcagcc
    10561 aatgaagtaa agttagatgt aacatctgaa gtggtaatag gtgtgctaga ttctaaggag
    10621 gaattgaaag agtcagaaaa tgatgctcca aaactagaaa ctcctcttag agaggagcca
    10681 agactagctc ctcaaacgct tccggaagca agtgaagttc ttgaaaacaa aagggaagag
    10741 tcaaaagtag agataacaga gccagctcaa gactcaccta ttcttgctcc tgtagaagaa
    10801 actaaagaag aagctgtgac agaaaaacca acaaatactc gttctctaac tgcagaagat
    10861 ttggtgaaga tttccaaagg ggaattgcat ttagaaaatg atttgattga tgaatctttc
    10921 tatggtgaaa aagctcttga tttggaaggg gatgatgacc aggatggcat caaaaacaaa
    10981 gatggtaagg attatctagg atataacagt catcccttgc tagcagacag tgatggggat
    11041 ggtttggcag atggggaaga tgataataag aaagaatggt atgtcacaga ccgtgattct
    11101 cttctcttta tggagttagc ttatcgagac gatgattata ttgagaaaat tttagatcat
    11161 aagaatcttt tccctagtct ctatcttgac cgtcaagaac acaaactcat gcacaatgaa
    11221 ttggctcctt tctagaagat gaaaaaagcc tactatacag atagtggctt ggatgctttc
    11281 ttatttgaga ccaagagcga ccttccttat ctcaaagatg gaacggtgca catgttggct
    11341 attcgtggaa cgcgagttaa tgacgccaag gacttgagtg cagatttggt tttattaggt
    11401 ggaaataaac tagctcaagc ggatgatatc cgcaaggttg ttggggaatt agccaaggat
    11461 ataagtatta ctaagttgta tatgacaggt cattctcttg gatgctacct agctcagatt
    11521 gcagaggttg aagcttacca aaaatatcct gatttttata accatgtatt gaggaaagtg
    11581 acaactttca gtgctcctaa agtgattact tccagaacta tttggaatgc taagaatggt
    11641 ttctgggatg ttggtttgga aagtcgtaaa ttagctgtta gtggaaaaat taagcattat
    11701 gtggttgata atgacaatgt tgtgactccc ttgattcata ataatcgtga tattgttaca
    11761 tttacaggta attcacgctt taaacaccgt tctcgtggct attttgaaag tccaatgaat
    11821 gatattccta actttaatat tggtaaacaa gctaccttgg ataaacatgg ttatcgtgat
    11881 ccgaaattgg ataaagtgcg attctttaag aaacaggctc tgcctcgatc ttctagtcaa
    11941 ccaagcgctg aaccaatgga aaatattgcc ttaggaaaac aggttactca aagttcgaca
    12001 gctttcggag gagatgctag aagagctgtg gatggcaaag tcgatggtaa ctatggtcac
    12061 aattctgtca ctcatacaaa cttccaatct aagccttggt ggcaagtaga tttggctaaa
    12121 gaagaaacca ttcgccaaat caatatttac aaccgaacag acactgccca ggatagattg
    12181 gcaaactttg atgtcattct tttagacagt tctggtaaag aaattgagtg aaaacgtata
    12241 atatctccta aagatgtgtc agcacaaatt acgattaacc ataaaaaagc gcgctatgtt
    12301 cggattgagc tagaaggcta taatgccctc agtcttgcag aagttgaagt tttccgcttt
    12361 atagctacga atgctgaaac ggcgacacaa gtttctaagc cagttcaacc aatcagtcag
    12421 actcctgtga aagataaaac attgacaatt caacacagtg gagcttacat tgcccgctac
    12481 tccataactt gggaagaagt tccagtagat aaagatggaa accaagttgt tcgtagtcat
    12541 tcttgggaag gaaacggtcg caaccagact gcaggttttg tcctcaacct cccaatcaaa
    12601 gaaaatatga gaaatctgcg agttaagatt gagaaaaaga cgggcctact atggaataga
    12661 tggcaaacaa tctatgaaaa cagaccaatt ttagctcaac cccaccgtaa aattacccat
    12721 tggggtacga cattgaattc caaggtgagt gacgatgatg tcttgtaatc tgatggtaga
    12781 atgacagtta gtttgtctag tttataagaa agtactacct gagcttgaat agaactcagg
    12841 tagctctcta tgaaagaaca aaattaatac tcaatgaaaa tcaaagagca aactaggaaa
    12901 ctagccgcag gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt
    12961 cacatatata atccaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtataaac
    13021 agaaaggtag agtgcgtgtt ctaatttgaa cacgagtaga aaacttttct aaaaacaaaa
    13081 acgaaaggat gggtaaactg tattcgctaa actgaatacg ggcgactctc ctctaaatca
    13141 aaattaagaa agaaaggaat tgaccccacc ctaaaagcag tgggaaaaag atagttggtc
    13201 tagcgagcat cgctcactgc gcccaactcc tattttccct tcgctttttg acgggtttgg
    13261 tatctttctc aatataaaat ataaaataaa gaaaggtaga gcgtgtgttt tgatttgaac
    13321 acgagcggaa aactcggaaa atagataatc tgactgaaaa atcaggattt ctcgtcaggt
    13381 tcctaatttt cagtcgtttt cttctcgctc tttgtatcat aaattatgtc tatccatatt
    13441 gctgctcagc agggtgaaat tgctgataaa attcttcttc ctggggatcc tcttcgtgct
    13501 aagtttattg cggagaattt ccttggtgat gctgtttgtt ttaacgaagt gcgtaacatg
    13561 tttggttaca ctggtactta caagggtcac cgtgtatctg tcatgggaac tgggatggga
    13621 atgccatcta tttcgattta tgcgcgtgag ttaatcgtag actacggtgt gaagaaattg
    13681 attcgtgtgg gaactgcagg ttctttgaat gaagaggttc atgttcgtga attagttttg
    13741 gcgcaggcgg ctgcaaccaa ctcaaacatc gttcgtaatg actggccaca gtacgatttt
    13801 ccacaaattg ctagctttga tttgcttgat aaagcctacc atatcgccaa aaaacttggt
    13861 atgactactc acgttgggaa cgttttgtca tctgatgtct tttactcaaa ttactttgaa
    13921 aagaatatcg agcttggtaa atggggagtc aaggctgtgg aaatggaagc agcagctctt
    13981 tactatcttg ctgcccaata ccatgttgat gcgctagcta tcatgaccat ctctgatagc
    14041 ttggtcaatc cagacgaaga cacaactgca gaagaacgtc aaaatacctt cactgatatg
    14101 atgaaggttg gtttggaaac cttgattgca gaataattat agccaaaaag gaagcccttt
    14161 atgaattgta ggacttcctt ttcttatcca gaaattgatc tagctctctc tgatttcgaa
    14221 gaatagtgac tttatgtgaa tattcttggc aaagtttttg gtaattttct ttttgagttt
    14281 tgctacgccc atcccaaaga atccatctga taaactccca ctcaaagcgt tcagggcaat
    14341 ctgccgccat actttctctg acttttccac ggtatttaag ataacgctta aaggctctaa
    14401 agagacaggt caatggcgaa aaattgagaa agatgatttg gtcagcttct tgcattcgtt
    14461 cttggtagta gcaccaagaa taattaccat cgatgaccca agctttatgc ttggtgagaa
    14521 agttttttat ctcggttaac atccattcgc agtcactgtc ttgccaacca ggttgaaatt
    14581 ggagtgtgtc catgtgcagt tttggaatgg agtagtagtt agataacttt tctgctagag
    14641 ttgacttacc agaaccagaa tatccgataa ttgcgatttt cattttctac cttttcctat
    14701 ttggagacaa aaaaacagcc tctatggact gtttcttatt tagcaagttt agctgaaaga
    14761 cgagctttat cgcggcttgc tttgtttttg tgaatcaaac ctttagtttc tgctttatct
    14821 atagctgagc tagcagcacg gaaaagttct tcagatgggt ttgcttcgaa agcttttata
    14881 gcagtacgca tagctgattt ttgagctgag ttcttttcgt tttgtttaac gttcaattca
    14941 gcgcgtttga tagctgattt aatgtttgcc aatgttctta cctccatatt tactaactat
    15001 accattatat atgaaaactt acgttttgac aagggaaaat tactttttta agtaaatttc
    15061 atcgatttca tggttcttgc ttttatgaag aatcacttct gcacgatttc tggttggttc
    15121 aatataattt tgcagatttg tgaggttgat actgctccag acctgatggg caaaggactc
    15181 cacttcccca atcggcatct gagtaaaacg ataatagtag ctatcagggt cgttttgggc
    15241 taggctcagc attttcaaga aacggtccag ataccaactt tcaatatcat ccactccagc
    15301 atctacatag atggaaaagt caaagaagtc agtgatatag agacgatcgt tttgtggatt
    15361 ttgaaagaca ttaattccct caacaattac aaaatcagca gctttgacac tttgtttctt
    15421 ttcgggtacg atgtcgtaaa cttcatgaga atagacagga atatctacat cttgtccatt
    15481 tttgatgcgg tccaagaagt tgagaagagc ttccatatca tagctttcag gaaatccttt
    15541 acgatttaaa ctcccctgct caatcaaggt ttgattggga tagagaaaac catcagttgt
    15601 aaccaactca accgtagcat ctgtaaacgt acgggacagt aggatttgaa gtaggcgact
    15661 ggttgtggat tttccaacgg caacactccc agaaacccca ataataaaag gttgagattt
    15721 actttcacgt tggaggaaaa ttccttttga aaaggctaaa tcttccttag ttcgcttgta
    15781 aatctgaatc agatgagcca aggggagata gatatctgta acgtcttgga gactgatttg
    15841 gtcattaaaa ctcttgatag attccaattc ttcttctgtc aaaggaggtg ttgtcttgcg
    15901 atgtaaagat tgccaagtct ggcggctgat tttttcaaaa tgtaaaaatt cgttggtcat
    15961 ttgttttccc ctagatattt tgtctatcat accataaaaa gctaaaaaaa taaagcggtt
    16021 tcttgaatgt ggtaagtcaa tgatatatag tataagtgat caatttattg atgaaatagg
    16081 agatagattc tactgattta taagcttata aaggaggctt tttagttcac aacttatagg
    16141 aggtgtacta tgaaaatctt aaaacgttac atattggaac tctgttttat tttaagtttt
    16201 gctttacctt ttataaaagg aaccaatgca gataatggta gatgctttgt ggaaacctat
    16261 tacggtttta cttttttgat ggaacatgct attgtaacag ctgtctttat ctgttcgttc
    16321 ttaattgctt tcttactaaa aaacgatggg cgaaatggat tgctgctggt agttattgct
    16381 ttttagtcct atggattgcg acagagggtt atttcttcca tatgtcacca gaagatttga
    16441 tacgactttg gacaagtttg gaaatcctga cacaaacgta tcagttgggc ttttatctaa
    16501 acattttgtt aggaattttg ttgatgatta agcatttgaa ggttaagcaa tagaaataat
    16561 aatctgcctg attatagatg ataaactttt tgtttttatc tggactgtga tatttatagt
    16621 tctaaatggt ttattattta taagtgttga aagagattga agaaaatggc ttcgtgactc
    16681 gctttcttcg gtctttttcg ttttattatc aatttgtaaa cgatttacaa tttgagtcaa
    16741 attatggtaa aatagtgtca tgagtaaaat gtattatgca gaaaatcctg acactgctca
    16801 cgacattcat gagttgagag tagagttgtt gggacaaaaa atgacctttt taacggatgc
    16861 gggtgttttt agcaagaaaa tagttgactt tggaagtcaa ctattgctca agtgtcttga
    16921 ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt tacggacctt tgggtttgtc
    16981 cttagctaag gcttatggag ttcaggctac tatggttgat atcaacactc gtgccttgga
    17041 tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg acgattttcc agtccaacat
    17101 ctatgaacaa gttgaaggac attttgatca tgtcatttcc aatcctccta tccgtgcggg
    17161 caagcaagtc gttcatgaaa tcattgagaa aagtaaagat ttcttggaaa ctggtgggga
    17221 tttgacaatc gtcatccaga aaaaacaagg ggctccaagt gctaagtcca agatggagga
    17281 tgtgtttggt aattgtgaaa tccttaaaaa agacaaagga tactatatcc ttagaagtgt
    17341 gaaagaatga gagcagttga tttaatccaa aaaaaacgag acggtcaaga actgacttca
    17401 agtgaaattg aatggctggt agaaggctat gtgtcaggaa ctgttcctga ttatcagatg
    17461 tctgcttttg ctatggctgt ttattttaaa ggaatgacga ctcgtgaaat ttctgattta
    17521 acgatgaata tggttaagac tgggcaagag tttgacctgt cagccattga tggtgtgaaa
    17581 gttgacaagc attctactgg tggtgtcggc gataaggtaa ccttgatttt agctcctctt
    17641 gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc gtggtcttgg ccatacaggc
    17701 ggaacaattg ataaattgga gtccattagg ggctatcaag tagaacgtag tcaagaggat
    17761 tttattcgtc aggttcagga tattggagta tctgtcattg ggcaatcaga ccagctggtc
    17821 aaagcagata agcttctcta tgcccttcgt gatgtgaccg caactgtcga cacgattcct
    17881 ttgattgcga gttcggtgat gagcaagaaa attgcggcag gggcggatgc tattttgcta
    17941 gacgtgactg tcggtgaggg tgccttcatg aagacggttg atgaggcgcg tgagttggct
    18001 caaactatgg tagatcttgg taaggttgtt ggacggaaga caatagcagt gattacggat
    18061 atgagccagc ctttgggacg agcgattgga aatcgtctgg aaatccttga agcattggag
    18121 attttgcaag gtcaaggacg tcaggatatt acccacttta tttgtgaatt ggctcaaatt
    18181 atgcttggtt tggcaaatgt taacaagact gttgaagaag ttcaccaaca tcttgagaat
    18241 ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc aaggtggaga cttggaagac
    18301 ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc ctgctcagga aacgggtgtc
    18361 atttcagctc ttccagctat ggactttggt ctttatgcca tgaggctggg tgctggtcgt
    18421 gcagttaagt ctgatgcctt ggactatgaa acaggaattg tttttgaaaa gaagattgga
    18481 gactccgttc aaaagggtga aattgttgca aaagtataca caaatgaaaa aattccacct
    18541 caactagtta cagatttcca aaaatgtgtt aaaataagtg atgaagtgaa aaaaatccgt
    18601 gaaattgtag aaatcatctc ctaaatggag ggaaaaccga aatgaaatta aataaatata
    18661 tagatcatac gcttttaaaa caagatgcaa agaaaaaaca aattgatagt ttgttgtctg
    18721 aggctagaga gtatgacttt gccagtgttt gcgttaatcc gacctgggtt gaacatgcta
    18781 aaaaaggact tgaaggcaca gatgttaagg tttgcacagt agtaggtttc cctttgggag
    18841 caacaacttc agccgtgaaa gcatttgaga caaaagaagc tatccaaaat ggtgcaggtg
    18901 agattgatat ggtgatcaat gttggagctc tcaaatcagg taatttagcc ttggttgagt
    18961 cagatattcg cgcagtagtg gaagcaagtg gtgataagtt agtgaaagtc attattgaag
    19021 cttgccttct gacagaccaa gaaaaagttg ttgtttgcca attggcccaa aaagctgggg
    19081 ctgactttgt caaaacatct actggctttt caactggtgg tgctacgata gcagatgtta
    19141 cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa ggccgccggt ggagctcgtt
    19201 cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac ccgtatcgga acgtcagctg
    19261 gggtagctat tttaaaagga gaattggcag atggcgacta ctgagttgat tgaactggca
    19321 attgaaacca gcaaacatgc ctatgtcccc tattctcact ttcctatcgg agcagtttta
    19381 gtagctaaag acggaagtgt ttacacggga gtgaatatcg aaaatgctag ctatcctttg
    19441 accaattgcg gtgagagaac agcagttttt aaggctatat ctgaaggcca aagagaattt
    19501 tcagaattga ttgtctatgg tcaaactgaa aaaccgatct cgccatgtgg tgcttgtcgc
    19561 caagtaatgg tcgaattttt tgaacaagat ttaaaagtga ccttagtcgc aaaagataaa
    19621 tcgacggtcg agatgacggt cggggagtta cttccatact cttttacaga cttaaactag
    19681 tctgagtcgc tctttgagtg gcacggtcct tgtggccaac caatccatac ttgcaacatc
    19741 gttgcacatc ttatttagga ggttcagtaa tgaacaagaa acaatggcta ggccttggtc
    19801 tagttgcagt ggcagcagtt ggacttgctg catgtggtaa ccgctcttct cgtaacgcag
    19861 cttcatcttc tgatgtgaag acaaaagcag caatcgtcac tgatactggt ggtgttgatg
    19921 acaaatcatt caaccaatca gcttgggaag gtttgcaaga ctggggtaaa gaacacaatc
    19981 tttcaaaaga taatggtttc acttacttcc aatcaacaag tgaagctgac tacgctaaca
    20041 acttgcaaca agcggctgga agttacaacc taatctttgg tgttggtttt gcccttcaca
    20101 atgcagttga agaagcagct aaagaacaca ctgacttgaa ctatgtcttg attgatgatg
    20161 tgattaaaga ccaaaagaat gttgcgagcg taactttcgc tgataatgag tcaggttacc
    20221 ttgcaggtgt ggctgcagca aaaacaacta agacaaaaca agttggtttt gtaggtggta
    20281 tcgaatctga agttatctct cgttttgaag caggattcaa ggctggtgtt gcgtcagtag
    20341 acccatctat caaagtccaa gttgactacg ctggttcatt tggtgatgcg gctaaaggta
    20401 aaacaattgc agccgcacaa tacgcagccg gtgcagatat tgtttaccaa gtagctggtg
    20461 gtacaggtgc aggtgtcttt gcagaggcaa aatctctcaa cgagagccgt cctgaaaatg
    20521 aaaaagtttg ggttatcggt gttgaccgtg accaagaagc agaaggtaaa tacacttcta
    20581 aagatggcaa agaatcaaac tttgttcttg tatctacttt gaaacaagtt ggtacaactg
    20641 taaaagatat tgctaacaag gcagaaaaag gagaattccc tggcggtcaa gtgatcgttt
    20701 actcattgaa ggataaaggg gttgacttgg cagtaacaaa cctttcagaa gaaggtaaaa
    20761 aagctgtcga agatgcaaaa gctaaaatcc ttgatggaag cgtaaaagtt cctgaaaaat
    20821 aatggatgga agtcatttct taggaagcgg ccaagggccg cttttttaag agttgagaca
    20881 aagtcatttt gtctcagtaa agcttgctac tagacaaact agcaagtttt attgaaataa
    20941 aataagactc tgaaaggaag agcacatggc acacgaaaat gtcattgaga tgcgtgatat
    21001 taccaaggtg tttggtggat ttgttgccaa cgacaaaatc aacttgcacc tacgaaaagg
    21061 tgaaattcat gcacttttag gagaaaatgg ggctggtaag tccacgctaa tgaacatgtt
    21121 agcaggcctt cttgaaccaa ctagtggtga aatcgcggtc aacggtcaag ttgtcaatct
    21181 cgactcccca tctaaagcag ctagcttggg aatcgggatg gttcaccagc actttatgtt
    21241 ggttgaagcc ttcacagtgg ttgaaaacat cattttaggt agtgaattga ctaaaaatgg
    21301 tgtgctagat atcgctggag ctagcaaaga aatcaaggct ctttctgaac gttatggctt
    21361 agctgttgac ccttctgcca aggtagcaga tatctcagtt ggagcccaac aacgtgtaga
    21421 aattttaaaa acactttatc ggggggctga tatccttatc tttgacgaac caacggctgt
    21481 tttgactcca tcagaaattg atgagttgat ggctattatg aaaaatcttg tcaaagaagg
    21541 aaaatcaatt atcttgatta cccacaaatt ggatgaaatt cgcgcagttt ctgaccgtgt
    21601 tacagttatc cgtcgtggga aatcaattga aaccgttgaa attacagggg ctaccaatgc
    21661 tgatttggcg gaaatgatgg taggacgttc tgtttccttt aaaacagaga agcaagcctc
    21721 taaaccaaaa gaagtggttt tgtctatcaa agatttggtg gtcaatgaaa accgtggtgt
    21781 tccagctgtt aaaaatctgt ccttggatgt tcgtgctgga gagattgttg gtattgcggg
    21841 gattgatgga aatggtcagt ctgaactgat tcaagccatt acaggtcttc gtaaggttga
    21901 atctggtagc attgagctaa aaggagattc aattgtaggc ttgcacccac gtcagattac
    21961 agaactaagt gttgggcacg ttccagaaga ccgtcaccgt gatggcttga ttttggaaat
    22021 gatgatatct gaaaatattg cccttcaaac ctactataaa gaaccacata gtaaaaatgg
    22081 aattttaaac tattcaaata ttacttctta tgctaaaaag ctgatggaag agtttgatgt
    22141 tcgcgttgcc agtgaattag ttcctgcagc tgcactctca ggaggaaatc aacaaaaagc
    22201 aattattgct cgtgaaattg atcgagttcc tgatctcctt atcgttagcc agccaactcg
    22261 tgggttggat gtcggtgcca ttgagtatat ccacaaacgc ttgattgaag agcgtgataa
    22321 tggcaaggct gtccttgttg tcagctttga attggatgag attttaaacg tctcagaccg
    22381 tattgccgtt atccacgatg gtaagattca aggtattgta tcaccagaaa caaccaataa
    22441 acaagaactt ggtgtcttga tggctggtgg aaacttggga aaggagaaga gtgatgtcta
    22501 aaaaattaca acaaatttcg gttcccttga tttctgtatt cctaggaatt ttactcggag
    22561 ccattgtcat gtggatcttc ggttatgatg ctatttgggg ctacgaagaa ttgttctata
    22621 cagcctttgg cagtctgcgt gggattggag aaatcttccg tgctatgggt cctctggtct
    22681 tgattggtct tggttttgcc gttgccagtc gagctggttt ctttaacgtc ggacttcctg
    22741 gtcaggcttt ggcaggttgg attctcagtg gttggtttgc cttatcgcat ccagatatgc
    22801 cccgtccctt gatgattctg gcaactattg tgattgcctt gattgctggt gggcttgtcg
    22861 gagcgattcc aggtattctt agggcctatc tagggacgtc agaggttatt gtaactatca
    22921 tgatgaacta cattgtcttg tatgtaggaa atgcctttat ccatgccttc cctaaagact
    22981 ttatgcaaag tacagattcg accattcgtg ttggggctaa tgcaacctac cagacacctt
    23041 ggttgtctga gttgactggt aactcacgga tgaatattgg tattttcttt gccatcattg
    23101 ccgttgcagt catttggttc atgctcaaga aaacgactct tggttttgaa attcgcgcag
    23161 ttggtctcaa tccacatgct tcagaatatg cgggtatttc tgcaaaacgg acgattatcc
    23221 tctcaatgat tatttcaggt gccttggcag gtcttggtgg tgctgttgaa ggacttggaa
    23281 ccttccagaa cgtctatgtt caaggggcat cattagctgt tggatttaac ggaatggcgg
    23341 ttagtctgct tgcagccaac tcaccaatcg gtattctctt tgcagccttc ctatttggtg
    23401 ttctccaagt tggagcccct ggtatgaatg cggcgcaggt accgtctgag cttgttagca
    23461 ttgtaacagc gtctattatc ttctttgtca gtgttcatta ccttatcgaa cgctttgtca
    23521 aaccgaaaaa acaagttaaa ggaggtaagt aaagatgtct attacaacct tgctcaccct
    23581 tttggtatct tctatgctga tttactcagc acccctcatc tttacaagta ttggtggtgt
    23641 tttctctgaa cgtggtggtg tggtaaacgt cggccttgaa ggaattatgg ttatgggtgc
    23701 cttttctgga gttgtcttta accttgaatt tgcagaacaa tttggagcag caactccatg
    23761 gctatctttg ctagttgcag gattggttgg atgcctcttc tctatcatcc acgcagcagc
    23821 gacggttcat ttccgtgcag accatgttgt cagcggtacg gtattgaact tgatggcgcc
    23881 agccttggct gttttcttag tcaaagttct ttataacaaa ggacaaaccg acaacctaag
    23941 tcagactttt ggacgctttg acttcccagt cttggcaaat atcccagtga ttggtgatat
    24001 cttcttcaag tcaactagtc tgcttggtta tatcgcgatt gccttctcat tccttgcttg
    24061 gtttatcctc ttcaagaccc gatttggtct tcgtctccgc tctgtaggtg aacatcctca
    24121 agcagcggat accttgggaa tcaatgtcta caagatgaga tatctaggag ttatcatttc
    24181 aggtttccta ggtggaattg gcggagcgat ttatgctcaa tccatctcag ttaacttctc
    24241 ggtaacaact attgttggac ctggatttat tgctcttgct gcgatgattt tcggaaaatg
    24301 gaatccaatc ggagccatgc tatctagtct cttctttggg ctttcacaaa gtttggctgt
    24361 tatcggttct caattgccgt tcctacaagg agtgcctaca gtttatcttc aaatcgcacc
    24421 ttatgttttg acaactcttg tctcagcagc cttctttgga aaagcagtcg caccaaaagc
    24481 agatggtatc aactacatca aatcaaaata agcatacaaa aaaacgtcag tccaatga
//
LOCUS       DAVFJR010000029        24215 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVFJR010000029 DAVFJR010000000
VERSION     DAVFJR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.030"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            37..1293
                     /locus_tag="VU722_001481"
     CDS             37..1293
                     /locus_tag="VU722_001481"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU1772428.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(1371..3434)
                     /locus_tag="VU722_001482"
     CDS             complement(1371..3434)
                     /locus_tag="VU722_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU1772429.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3436..3714)
                     /locus_tag="VU722_001483"
     CDS             complement(3436..3714)
                     /locus_tag="VU722_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772430.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            3866..4714
                     /locus_tag="VU722_001484"
     CDS             3866..4714
                     /locus_tag="VU722_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU1772431.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            5337..5909
                     /locus_tag="VU722_001485"
     CDS             5337..5909
                     /locus_tag="VU722_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772432.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIHSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(6954..9212)
                     /gene="glgP"
                     /locus_tag="VU722_001486"
     CDS             complement(6954..9212)
                     /gene="glgP"
                     /locus_tag="VU722_001486"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU1772433.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKLMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(9238..10755)
                     /gene="malQ"
                     /locus_tag="VU722_001487"
     CDS             complement(9238..10755)
                     /gene="malQ"
                     /locus_tag="VU722_001487"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU1772434.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            11305..12576
                     /locus_tag="VU722_001488"
     CDS             11305..12576
                     /locus_tag="VU722_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1772435.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            12687..13979
                     /locus_tag="VU722_001489"
     CDS             12687..13979
                     /locus_tag="VU722_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1772436.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            13981..14823
                     /locus_tag="VU722_001490"
     CDS             13981..14823
                     /locus_tag="VU722_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1772437.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            15084..15884
                     /locus_tag="VU722_001491"
     CDS             15084..15884
                     /locus_tag="VU722_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU1772438.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTKELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFKTFKECYHFILNCL
                     GLPTLITLILGLFGQNMSNLITVQNILFVLYLVTIFYKTHFRDPDYHK"
     gene            15894..16880
                     /locus_tag="VU722_001492"
     CDS             15894..16880
                     /locus_tag="VU722_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1772439.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            17016..17096
                     /locus_tag="VU722_001493"
                     /pseudo
     CDS             17016..17096
                     /locus_tag="VU722_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(17172..18113)
                     /locus_tag="VU722_001494"
     CDS             complement(17172..18113)
                     /locus_tag="VU722_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU1772440.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(18091..19854)
                     /gene="aspS"
                     /locus_tag="VU722_001495"
     CDS             complement(18091..19854)
                     /gene="aspS"
                     /locus_tag="VU722_001495"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU1772441.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(20045..20125)
                     /locus_tag="VU722_001496"
                     /pseudo
     CDS             complement(20045..20125)
                     /locus_tag="VU722_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20161..20391)
                     /locus_tag="VU722_001497"
     CDS             complement(20161..20391)
                     /locus_tag="VU722_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772442.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(20409..21050)
                     /locus_tag="VU722_001498"
     CDS             complement(20409..21050)
                     /locus_tag="VU722_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772443.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATSSLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKIGFNRFIWLPALIWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(21062..21796)
                     /locus_tag="VU722_001499"
     CDS             complement(21062..21796)
                     /locus_tag="VU722_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU1772444.1"
                     /translation="MKKRRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKILIP
                     WISAICLVLVFISILLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHINPQTFFLSFLLFVVFLVAQKYLFKTIAIVRQFDLE
                     FFATPKDILNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(21799..21996)
                     /locus_tag="VU722_001500"
     CDS             complement(21799..21996)
                     /locus_tag="VU722_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772445.1"
                     /translation="MNKYKVIYYVVVIALSVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(21996..22202)
                     /locus_tag="VU722_001501"
     CDS             complement(21996..22202)
                     /locus_tag="VU722_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772446.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(22212..22526)
                     /locus_tag="VU722_001502"
     CDS             complement(22212..22526)
                     /locus_tag="VU722_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772447.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLEKKIKKLERKEKGNTEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(22986..>24215)
                     /locus_tag="VU722_001503"
     CDS             complement(22986..>24215)
                     /locus_tag="VU722_001503"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1772448.1"
                     /translation="QVVQAADGARPQGVSSTLDSYRKTLHDLLGRLSLTEGEKEKYRN
                     QIDTATELDKLVELEGTLDNLQNKEIEEAVEKAKVTLPQYMDTRLKELDQTGSGFPDL
                     LKKLQNIIDEYREQLDGLPNKKAVEDLVEQAKEEMDGYIAEYQKTLTAGQDDNNGAGE
                     QAPQAGDNNGAGEQVPQAPQAGDNNGAGEQVPQAPQAPQAGDNNGAGEQAPQAPQAPQ
                     AGDQTFTGTVGSVNVTVLFDKPVNAEKVTVKEITEKDLVDKISRQAGGGSIRLFDLSL
                     TKDGKETHVNEERTVRLALEGLGENVQVYHVKPDGQLELLDSKVEDGHVIFRINHFSL
                     FAIKTMSTKSNQETPSNQATPSTQAKSTPKETTKDATSKKTLPNTGTADSTALLAAAA
                     STAILGLGLAGRRRKED"
BASE COUNT         7350 a         5203 c         4433 g         7229 t
ORIGIN      
        1 ggtagaaaca ataattttaa aaaggagaaa agacacatgc acatttttga tgagctaaaa
       61 gatcgtggtt tgatatttca aacgactgat gaagaagctt tgcgtaaagc cctagaagaa
      121 ggtcaagttt cttattatac tggctacgat ccaactgctg acagccttca cctaggccac
      181 cttgtcgcaa tcttgacaag tcgtcgcttg caactagcag gtcacaaacc ttatgcgctc
      241 gttggcggtg ctacaggtct catcggagat ccgtccttca aagatgctga acgtagtctc
      301 caaacaaaag acacagtaga tggctgggtc aagtctatcc aaggacaact ttctcgtttt
      361 cttgactttg aaaatggcga aaacaaggct gtcatggtca acaactacga ctggtttggc
      421 agcatcagct tcattgactt cctccgtgat attggaaaat acttcacggt caactacatg
      481 atgagtaagg aatctgtaaa aaaacgaatc gaaacaggaa tttcttacac tgagttcgct
      541 taccaaatca tgcaagggta cgacttcttc gtccttaacc aagaccataa tgtcactctt
      601 caaatcggtg gttctgacca gtggggaaat atgacagctg gtaccgaatt gcttcgtcgt
      661 aaagcggaca agactggtca cgttatcact gttccactaa tcacagatgc aactggtaag
      721 aaatttggta aatcagaagg aaatgccgtc tggctcaatc ccgaaaagac ttctccatac
      781 gaaatgtacc aattctggat gaacgtgatg gacgctgacg ctgttcgctt cttgaaaatc
      841 tttactttct tgtcacttga tgagattgaa gatattcgta aacaatttga agcagcgcca
      901 cacgaacgct tggctcaaaa agtcttggct cgtgaagttg ttacacttgt tcacggagaa
      961 gaagcctaca aagaagcact taacatcact gagcaactct ttgcaggaaa catcaaaaac
     1021 ctttctgtca aagagctcaa acaaggactt cgtggtgtgc caaactacca agtacaggca
     1081 gacgaaaaca acaatatcgt ggaactgctc gtctcatctg gtatagttaa ctcaaaacgc
     1141 caagcccgtg aagacgtcca aaacggagcc atctacgtaa acggcgaccg catccaagag
     1201 cttgactatg tcttgagtga cgctgataag ttagagaatg aactgactgt tatccgtcgt
     1261 gggaagaaaa aatactttgt attgacttac taaactattc aacatttatc tataaacaaa
     1321 ggagttagcc tcgagaaagg taactccttt ttgctgttaa taactctcat ctatctattt
     1381 ttaatagaca ggctacgcag gacaatgcgc aaggttgtta gattatgtaa gatagagaga
     1441 tttgaaggac tgagccaatt aaataagccg aagccaatca aactactatt tacgacaacg
     1501 gtatcttgaa tatttttctt gatgagtgtt tgcaaagatg atgataacga atccaactct
     1561 tggaagaaat ccaaacgatt atctaacaat aagatatcac tcatctgctt agaaatatct
     1621 gcactctcat tcatcaccac accgatatct gatagagtta aagccgctga gtcattcaat
     1681 ccatctccaa ccatcaaaat agtgtgacct gctttctgca gtttctctac taactcaaat
     1741 ttcccatcag gtttcaagtc tgtatagacc tgatcaaagg gcaaatcttt gactaattcc
     1801 tctgtcctag tcaaggtgtc tcctgttgcc agaatcaatt ttttcccctg tgccttaagt
     1861 ttatccaagg ctgtttttgc ttcttttctc aaaggagtat gaatgcagaa cattccaatc
     1921 aattcatttt gataagccaa gaataagaga ttgtagtgac tcttgtactc ttcaattaaa
     1981 gcattttgtt ctgaactgat atgaatctgc tcatcctgca tcaagacata attcccaata
     2041 agaactggtt ggccatctat atgagatttg atccccttgc ttgcgatata ttggagtttc
     2101 ccatgcattt cctcatgttc aattccctct atctcagctt gcttgacgat ggcattagca
     2161 ataggatgat aaatgtgttc ctcaagacag gcactgattc tgagaatatc ttcctcacta
     2221 tagtctccaa aaggtaacac cttttcaact ataggataac tagttgtgat tgttcctgtc
     2281 ttatcaaaca agaaagtatc aacttccaga tatttctcca gaacatctcc atccttaatc
     2341 accatttcac ggttcaaccc ttccttgata actgtcaaat aagctacagg agtagagatt
     2401 ttcaaagcgc aggagaaatc gaccaatagg aaagaaatag ccttagaaaa agaacctgtc
     2461 aataggtaag tcagcccagc ccccaagaaa ttatatttga cgactttatc cgccatcttg
     2521 atgaaatagc gttgtttcgt tttcttgttt tcttcagatt tcttcatcaa ctcaatcagc
     2581 tgtaaaagac ggctgttcat ctgattatct gttacacaaa tgcgtaactc tccagtttct
     2641 aatactgtat ttgcacaaac caaatcagac tctctttttt caactggaaa actctctcct
     2701 gtcaaggaac tttcgttgac catacctaaa cctgaaacta cttgtccatc aaacagaatt
     2761 tcatttcctt gagataagat caagacatct cctatttgaa catcggaact cttgatacta
     2821 acaaccgtat cgccctgtac taggaataca tcgctctctt ttgcaagaag actctgttct
     2881 aaatctgttg cagttttttt caaggaccac tgatctaaat gattccccaa atcaagcata
     2941 aacatgatat tgctagctgt cttggattgg ttcataaaca aagacaataa aatagccgaa
     3001 cagtccaaga cttccatcgt tagttcctta cgcgctagtg tttgataggc ttctctaata
     3061 taacccaaag cctgataaca agtccatata tagcgaatag gatacggcac aaaactacga
     3121 aaaagtacac gcttaaccgc tgcacctgaa acaatagaat aagcactctc ttctctacga
     3181 atgggaagag tcatcaactc agaaactttc cctttatcaa ttctttttaa aaaggcttct
     3241 gcattatcta atacagaaaa gccttctttt atgcgtagag taaagtgctg ttgatccatg
     3301 taaaactgga tagactcaat ccccttttca tctctcgcca aggaacgaag atagtcttga
     3361 atatccaagg taagtgaaaa agaagatgat agtcggatat gttggtatcc tctatgtagc
     3421 actttaaaag acatattatt cacctataag gctatctaat tgctcttctt ttttctcttg
     3481 ctcgtacaaa tatttggcat cttgcaagac atcgtctcca tgttgcttca caacagaaac
     3541 agatgcatct agctcgtctt tcaacttgta agccttagcc aaagctttag aataaccttt
     3601 tttagcttcc ttacttgcta agattttcaa accaagggta ccaaatgcga caccacccaa
     3661 aaataatgaa gattttttcg caacttttgc aacggttaat acttctttta acatacttat
     3721 ttcctcctta tcattattat atagcaattt agatataaaa gcaatttcat tctataaatt
     3781 ggagaattag ttttatttct actgaatctc ccatctactt attcctaaag ttgctttcat
     3841 ttgcctcttt tgatacactt aaactatgaa tacaaatctc aagcccaaac ttcagcgttt
     3901 tgcttctgcg actgcctttg cctgtcctat ctgtcaagaa aatctgactc tgttagagac
     3961 taatttcaag tgctgcaacc gtcattcttt tgacttggcg aaatttggct atgtcaatct
     4021 agcacctcaa atcaagcaat ctgctaacta taacaaggaa aattttcaaa accgtcaaca
     4081 aatcctagaa gccggctttt accaagctat cttagatgct gtatctgact tgcttgcaag
     4141 ctcaaaaact accacaacaa ttttggatat cggttgtggt gaaggattct attctcgcaa
     4201 actacaagaa agtcactctg aaaaaacttt ctatgccttt gacatctcca aagattcagt
     4261 ccaaatcgct gctaaaagtg aacccaactg ggcagtcaat tggtttgttg gcgacttggc
     4321 acgacttcct ataaaagacg ctaacatgga tattctgctt gatatcttct cacctgccaa
     4381 ctatggagaa tttcgtcgcg ttttatccaa agacggtatc ttgataaagg ttatcccaac
     4441 tgaaaatcac ctcaaagaaa tccgtcaaag agtacaggac cagctgacaa acaaggagta
     4501 ttctaaccaa gatatcaagg agcatttcca ggaacacttt accatcctat ctagtcaaac
     4561 tgcctctctg actaagacta tcacagcaga acaactccaa gccctactca gtatgactcc
     4621 tctcctcttt cacgttgacc agagcaagat tgactggagc caactgacag agattaccat
     4681 cgaagcagag attttggttg ggaaagcatt ctaaactaga cttcccaaag gtataaaact
     4741 taccgaaaat cttcaatatt ataaaaacgc ataagaacag gtacacaaac cttaatctta
     4801 tgcgttttgt tatagtttcc atacacatta aggggaaata gttgaaatca gttctcttaa
     4861 taaccattga ataccatata ctacatttac cccaaatatg atataggccg tataaatcaa
     4921 gtatttcgat ttttcccgcc tcaaagaata gatcttatac aaaataaata aatttaaaat
     4981 aataaataat agagacaaaa tcttcctcca aaatcaatat taaaagtagc cagtcaatca
     5041 tagttctaat ctttattttc gattcgaaat tacaaactta tcaatgaaca ataagtgata
     5101 taaggccagt accagacccc aaacgctacc acgaaaagag aattcttgat gattgaaagt
     5161 aaacaaatca tggttaccaa tatagaggca ggtcaaaata acaaataaaa tccaaaataa
     5221 atccgtccat ttatattttt aaaaatattt ttttaacata atagcatatt tttcttgact
     5281 ataataacag tatataataa aatgtaagca gatacaaata aaaaggagaa aagctcatga
     5341 acaaattaat gaaatttatt tcggtttttt tgacgtcaat tgtgttaatt gtatcagcga
     5401 ttccaagtgt ttcagctgta tacgcttctg aacaagtatc acaaattgaa acaaatatgg
     5461 aacttcaacc tgtcacttct ctaacagaag aacaaatcaa tacacttgca aacgaaatcc
     5521 actcttttca tccagacgtc tcacaacaat ggatcaaaga agtaattaac cgacaattac
     5581 aaggcgatta tacaatccca cctacatact ctccatttag agcagcttgg caaggtatta
     5641 cagttaatca aatgggtgct ctattagata ctgcaatagc tttagcatta ggaggaacta
     5701 ctgcaggcct tgcaaatcta attaaagtaa aaggaaaaca tgcagcaaaa agtgctattc
     5761 gttcagcaat ttctagatat ctaggtaatt ggtttgtaaa tgatgttgct ttagaatccg
     5821 ctatgaattt attatcaccg gggacttatt tagcacaatt atgggataaa aatgatgcca
     5881 ttcctaacaa cggaaggatt aacttttaat catgagatat acaataaaat taattgggta
     5941 taacgtattt tcgttgttta tattctttat cttatcaatg ttgtttaaag ttccctttag
     6001 gtggtggatc agcattgcaa tgacgacttc gtcgtacatt gtatataatt acttaaagaa
     6061 aaagagagaa aaggaatgat cttataccag atcattcctt ttctgctttc tgtaaatccc
     6121 tcggagtgtg tttggcgctt tgatacgaag tgtcaaagct gtataaacgt tactatttcc
     6181 aaaaaagtaa cagaaaattc ctgctttgta ggactgcttt gggtgagtaa tagacatgtc
     6241 gactcaccct atctcctgat ggcgaaaaga atttagcaat ggtgcaagtt gttctgaact
     6301 cgagaaaaaa catgccgaaa tcgaagaaaa gcgtgcagaa cttgaagcga agaagcaaga
     6361 aatgttgaag cgcttggata aatagaattt agaaaacaga aaaaactaaa aagaatgtag
     6421 ggtttatttc cctacattct taaaataact tagtacataa atgacaatgc tgccactgcc
     6481 gtcaatattg caaaaactat tttccaaatt tttttatttt ttccaaaaat cttatcaggt
     6541 aacaagctta ttacaagaaa ggtaataaac aacaccaatt taagtgtgta tatcataaaa
     6601 acaccttctt tcctacaatt atattataat actttatgta agcgaataca agagatatga
     6661 ggtaaccaac tacgaaaaaa tataaggctg aagacagcaa aaaccagcat ttaaagcctt
     6721 cactgtatct aggatttccc tatttttaga caagattgac ccaaatccac agcatttaaa
     6781 aaagcgaatt tcaatcgaaa ctcgcttttt tacaagatgt attagtataa atttgtatct
     6841 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaagcacc
     6901 gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga gtattagttc
     6961 aagtgccaga tgtcttcatt atactgagcg attgtacggt cagatgagaa gaatcctgct
     7021 ttagaaatgt taacgatgac tttatccaac catgcgtcac ggtcttcgta gtcagcaagc
     7081 atttgctctt tgactttgat gtagtcttcc aaatcaagaa gagtcatgaa ccagtctttg
     7141 ttgatcaatt cattgtaaag acgttccaag cgctctttgt ttccagctgc aagaactgca
     7201 tcactaacga tgaagtcaac caatggtttg atagcttcac gagcgtagaa ttcgcttgat
     7261 ttgtaagctg cttttgcgta aaggtcgata acagtttctg aatcttcacc gaagatgtag
     7321 atgttttctt ctccaaccaa ctcagcgatt tccacgttag caccgtccat agtaccaagt
     7381 gtcaaagctc cgttcaacat gagtttcatg ttaccagtac ctgaagcttc tttagaagca
     7441 agtgagattt gttctgagat atcacatgct gggataagga aacttgctgc agtaacgttg
     7501 tagttttcaa ccataactac ttgcaagtgt ggagctactg ctggatcgtt agcaataact
     7561 tctgacatgc aaaggattaa atggataatg tcttgagcga ttgtgtaggc tggagctgct
     7621 ttaccaccaa agaagattgt gattggacga gcagggatgt taccagcttt gatgtcaagg
     7681 tatttgtgga tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg aagacgtttg
     7741 atttggatat caaagataga atttggattg atttccacac cttggtgttc tttcaagtga
     7801 cgagccaatt tacgtttgtt gtgagccttg atgctttcca atttttcttt gacagctgct
     7861 ttgtcttcat aagacaaaag tttttcaagc tcatctgctt catggtgcca accatctcca
     7921 agaatctcat ccaagtagtg agacaatctt gggttagcat gcataagcca acgacggaaa
     7981 gtgataccgt ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa ggctttcaac
     8041 tcagaatttt tcaagatttc agtatggagt gctgcaaccc cgttaacact gtatccgtag
     8101 tggatatcca tgtgagccat gtgaacacgt ccgctctcat cgatgatttg aacagctgga
     8161 tctttgtact ctgccttcac acgacggtcc aattcttcga tgattggtac caagtgagga
     8221 accacttctt gcaagaattc aagaggccat ttttcaagcg cctcagcaag gattgtgtgg
     8281 ttagtgtagg cagtcatgct acgaacaatt gagattgctt cgtcaagctc gataccacgt
     8341 gcagtcaaaa gacgaatcaa ttcaggaatc accattgatg ggtgagtatc gttgatttgg
     8401 acaactgcgt agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc ttcgtcgatg
     8461 atcaattgcg caccgtttga aaccatgaag tattgttgga agatacggag caattcacct
     8521 tgacggtcac tatcatctgg gtaaaggaag agagtcaagt tgcgagcgat atctgtcttg
     8581 tcaaagttga taccatcttt aataatagaa gaatcaactg aatccaagtc aaacaaacgc
     8641 aagcggtttt tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag agttgatgtc
     8701 aaagtaaagt ctgcaaatgg tacttggtag ctacggcttg agcgaaccaa ccagttttgc
     8761 tctgtcaacc atgcatttgg aattgtttct tgttggttgt ttttaagaac ttgttggaaa
     8821 agaccaaagt ggtagttaag accaacaccg tcaccattca aaccaagagt agcaattgag
     8881 tcgataaagc aggcagccaa acgtcccaaa ccaccattac caagagatgg ttccaattca
     8941 acttcttcaa cttcgatcaa gtctttacct gcagctgcaa gttctttttt aacatcgtcg
     9001 taaagaccaa ggttaatcaa gttgtttgac aagagtttac caatcaagaa ctcagctgag
     9061 atgtagtaaa cttttttctt accagtgttg actggttttt ggctgcttgc aagcttgctg
     9121 tagttaagaa gagcaaggta aagctcttca ttgctacatt ctgcaatggt tttattgtaa
     9181 cgattttgta caaattcttg tagtgataac atgtttagtt gtctcctgat tattgtctta
     9241 tttctttaaa tctaccaaat tttcattaat tcggcgataa attgttgtca agtcaagcaa
     9301 accttcctcg acagctggtg tcaattgatc ttcagtcata cgccaagacc agtttccacc
     9361 aagggtagat gggaagttca tacgagctgc ctcatccaat tctagtaaat cttgcatagt
     9421 cgcaattgcc ataaagctaa ctgatgaaaa tactgtacga agcatagcgt gtaccactgt
     9481 ttcgtattct ttacggttcg tgtaacgagc catgtactca cgagtcgcat catcaatctc
     9541 attacggtac caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca taactgagtt
     9601 agcaggtgcc aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg caaattgaag
     9661 aatcttcatt cctgggaagc cagtacgttc acgcaattcg atcacttcat ctgtcatgaa
     9721 gccaaggtct tctgcgatga tgtttagctc accaagttct tccttaacgg ctgcaaaaag
     9781 cttgtagcct ggacctttca cccactcacc aggtgctgct gtatcggaac cagcagggat
     9841 ttcccaataa gattcgaagc cacggaagtg gtcgatacga acgatatcgt agattttgaa
     9901 gctttcacgc aagcgttcaa tccaccattt gtagccgtct ttgtccattg cttcccagtc
     9961 atagattggg ttaccccaaa gctgaccagt tacagaaaac tcatctggtg ggcatcctgc
    10021 gatacaagta gccttaccat tgacatctgt tttgaagaga tgtggatttg cccacatatc
    10081 acttgaatct tccgctacgt agattggcat gtccccaacg atttcaatgt ggttgtcgtt
    10141 agcgtaagct ttcaatttca accattgttg gaagaagaag tattgagtca cacggtggta
    10201 aaccaacttg tctgccaatt gctcacgata gctttcaagt gctgaagctt tacgagcacg
    10261 agcatctgca tctggccatt cagtccaagc aagattgtca aaatgctctt tgatagccat
    10321 atactcagca aagagctcaa gccatgattg gttgtcttga gcaaatttct caaaatcttt
    10381 aacatctccg acttcaaaga aacgtttcac cgctttttct aaaagaggac gacgtgcata
    10441 gtagatttta gcatagtcaa cttcagacgc atcgctacca aagtcaactc cttcaaggtc
    10501 acttgcttcc aacaaacctt gctccaccaa gatatctaaa tcgataaaat gagtgtttcc
    10561 tgcgaaggct gagaaagatt ggtaaggaga gtccccgtaa ctagttgctc ctaatggaag
    10621 gatttgccag taacgttgtt ttgtacggac caagaaatca acgaagtcgt aagcactttg
    10681 accaaatgat ccgattccgt aagctcctgg aagagaagag atgtgcatca acacaccact
    10741 ttgacgtttt ttcataatag cacctcgtgt gttaaaataa tggaacgttg cgtattttgc
    10801 agacgcaaac gtttgcgtta cttataagta tactcctttt caagcataat tgcaagcgtt
    10861 tttaaaaaac ttttttgatt atttttaagg agactaactc attttagcaa agataactta
    10921 aaactatcta atcctaaagt ttgactctca cgagacagtc tacaaagtac aaaacctcct
    10981 tagggagctt gaatttatat gcaacaaagc acaaacgtct atagaaaata gatagggatt
    11041 agaaccaggg aggtagcccc tcctggtttc cctctttaga cagattccat atatttttat
    11101 taaaaatact gtattcttat ctatttcata cttttcttct attaaaatgc aaaattatgc
    11161 tatcaaatca agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc aaccgttttc
    11221 tatttgtgct atactaagct cataaaggaa aacgtttgcg tttccttatc aataaaactt
    11281 gctattcttt gggaggaata cactatgtca tctaaattta tgaagagcac tgcggtgctt
    11341 gggactgtta cacttgctag cttgcttttg gtagcttgcg gaagcaaaac tgctgataag
    11401 cctgctgatt ctggttcatc tgaagtcaaa gaactcactg tatatgtaga cgagggatat
    11461 aagagctata ttgaagaggt tgctaaagct tatgaaaaag aagctggagt aaaaatcact
    11521 cttaaaactg gtgatgctct aggaggtctt gataaacttt ctcttgacaa ccaatctggt
    11581 aatgtccctg atgttatgat ggctccatac gaccgtgtag gtagccttgg ttctgacgga
    11641 caactttcag aagtgaaatt gagcgatggt gctaaaacag acgacacaac taaatctctt
    11701 gtaacagctg ctaatggtaa agtttacggt gctcctgccg ttatcgagtc acttgttatg
    11761 tactacaaca aagacttggt aaaagacgct ccaaaaacat ttgctgactt ggaaaacctt
    11821 gctaaagata gcaaatacgc attcgctggt gaagatggta aaactactgc cttcctagct
    11881 gactggacaa acttctacta tacatatgga cttcttgccg gtaacggtgc ttacgtcttt
    11941 ggccaaaacg gtaaagacgc taaagacatc ggtcttgcaa acgacggttc tatcgtaggt
    12001 atcaactacg ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga tacagaaggt
    12061 gctggaaact taatccaaac tcaattccaa gaaggtaaaa cagctgctat catcgacgga
    12121 ccttggaaag ctcaagcctt taaagatgct aaagtaaact acggagttgc aactatccca
    12181 actcttccaa atggaaaaga atatgctgca ttcggtggtg gtaaagcttg ggtcattcct
    12241 caagccgtta agaaccttga agcttctcaa aaatttgtag acttccttgt tgcaactgaa
    12301 caacaaaaag tattatatga taagactaac gaaatcccag ctaatactga ggctcgttca
    12361 tacgctgaag gtaaaaacga tgagttgaca acagctgtta tcaaacagtt caagaacact
    12421 caaccactgc caaacatctc tcaaatgtct gcagtttggg atccagcgaa aaatatgctc
    12481 tttgatgctg taagtggtca aaaagatgct aaaacagctg ctaacgatgc tgtaacattg
    12541 atcaaagaaa caatcaaaca aaaatttggt gaataaaaaa tttgttcaag gggggtggaa
    12601 atcaaatccc cctttgaatt tatcaataga gacacaaata atttagcttt cttataaaaa
    12661 agtagtatcc tatgaaagga gttaatatgg aaaagcaaca acctagtaaa gcagccctgc
    12721 tgtctatcat tcctgggtta ggacagattt acaataaaca aaaagccaaa ggttttatct
    12781 tccttggtgt aaccatcgta tttgtccttt acttcctagc acttgcaacc cctgaattga
    12841 gcaacctcat cactcttggt gacaaaccag gtcgtgataa ttccctcttt atgctgattc
    12901 gtggtgcctt ccatctaatc tttgtaatcg tttatgtact cttttatttc tcaaatatca
    12961 aagatgcaca tacgattgca aaacgcatta acaatggaat tccagttcca cgcacactca
    13021 aagacatgat caaagggatt tatgaaaatg gcttccctta cctcttgatc attccatctt
    13081 atgttgccat gaccttcgcg attatcttcc cagttatcgt aaccttgatg atcgccttta
    13141 ccaactacga cttccaacac ttgccaccaa acaagttgtt ggactgggtt ggtttgacca
    13201 actttacaaa catttggagc ttgagtacct tccgttctgc ctttggttct gttctttctt
    13261 ggactatcat ttgggctttg gcagcttcta ctttacaaat cgtaattggt atcttcacag
    13321 ctatcattgc taaccaacca tttatcaaag gaaaacgtat ctttggtgtt attttccttc
    13381 ttccttgggc tgtcccagcc ttcatcacta tcttgacatt ctcaaacatg tttaacgata
    13441 gtgtcggtgc tatcaacact caagtattgc caatcttggc taaattcctt cctttccttg
    13501 atggagctct tattccttgg aaaacagacc caacttggac taagattgcc ttgattatga
    13561 tgcaaggttg gctcggattc ccatacatct acgttctgac cttgggtatc ttgcaatcta
    13621 ttcctaacga cctttacgaa gcagcttata ttgacggtgc caacgcttgg caaaaattcc
    13681 gcaacatcac tttcccaatg atcttggctg ttgcggcacc tactttgatt agccaataca
    13741 ccttcaactt taacaacttc tctatcatgt acctcttcaa tggtggagga cctggtagtg
    13801 tcggaggtgg agctggttca accgatatct tgatctcatg gatctaccgt ttgacaacag
    13861 gtacatctcc tcaatactca atggcggcag ctgttacctt gatcatctct atcattgtca
    13921 tttcaatctc tatgatcgca ttcaagaaac tacacgcatt tgatatggag gacgtctaag
    13981 atgaataact caattaaact caaacgtaga ctgactcaaa gccttactta cctttacctg
    14041 attggtctat caattgtaat tatctatcca ctgttgatta ccattatgtc agcctttaaa
    14101 gcaggtaacg tctcagcctt taaactagat actaatatcg acctcaattt tgataacttt
    14161 aaaggcctct tcactgaaac cttgtacggt acttggtacc tcaacacttt gattatcgcc
    14221 ttaattacca tggctgttca aacaagtatc atcgtacttg ctggttatgc ttacagccgt
    14281 tacaacttct tggctcgtaa acaaagtttg gtcttcttct tgatcatcca aatggtgcca
    14341 actatggccg ctttgacagc cttcttcgtt atggcgctta tgttgaacgc ccttaaccac
    14401 aactggttcc tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc ttggctcatg
    14461 aaaggctact tcgatacagt gccaatgtct ttagacgaat ctgcaaaact agacggtgca
    14521 ggacacttcc gccgcttctg gcaaattgtt cttccacttg ttcgcccaat ggttgccgta
    14581 caagctctct gggccttcat gggacctttc ggggactaca tcctctctag tttcttgctt
    14641 cgtgagaaag aatactttac tgttgccgta ggtctccaaa ccttcgttaa caatgcgaaa
    14701 aacttgaaga ttgcctactt ctcagcaggt gctatcctca tcgcccttcc aatctgtatt
    14761 ctcttcttct tcctacaaaa gaactttgtt tcaggactta caagtggtgg cgacaaggga
    14821 taatttatcc ccaccaccct ttttcatttt atactcttcg aaaatctctt caaaccacgt
    14881 cagctttatc tccaacctca aagttgtgct ttgagcaacc tgcggctagc ttcctagttt
    14941 gcactttgat tttcattgac tattagcgat tgtcactgta aataatatcc ttgtagcaag
    15001 caatttaccc cctagacttg aaataaagcg catttctcta tataataata ctcatataga
    15061 aaacaccttt tagaaagata cctatgcttc catatccatt ttcctatttt tcaagtattt
    15121 gggggtttcg taagcccctg tccaaacgtt tcgggctcaa ctggtttcaa cttctcttta
    15181 ccagtatctt ccttatcagc ttgtctatgg tacccattgc tatccaaaac agctcccagg
    15241 agacctatcc gctagaaact tttatcgata atgtctatga acctctgaca gataaggttg
    15301 tccaggatct ctctgaacat gctacaattg tcgatggcac attaacttat actggaacag
    15361 ctagtcaagc cccttctgtt gtgattggtc caagtcaaat caaggaatta cctaaggact
    15421 tgcaactgca tttcgacaca aaagaactgg tcatcagcaa ggaaagcaag gaattgaccc
    15481 gtatctctta ccgagcgatt cagactgaga gtttcaaaag taaagacagc ttgacccaag
    15541 caatttctaa agactggtac caacagaatc gtgtctatat cagtctcttc ctagttctcg
    15601 gtgcgagctt cctctttggt ttgaatttct ttatcgtctc tctaggggcg agtcttctcc
    15661 tttatatcac taagaaatca cgcctctttt catttaaaac ctttaaagag tgctaccatt
    15721 ttatcttgaa ctgtttagga ttgccgactc tgattacgct tattttggga ttgtttggcc
    15781 aaaatatgtc aaacctcatc actgtacaaa acattctttt tgtcctttat ctggtcacta
    15841 tcttttataa aacgcatttc cgtgatccag attaccataa ataggagatt tttatgcccg
    15901 ttacgattaa agacgtggcc aaggctgctg gtgtttcccc ttcaaccgta acccgtgtta
    15961 ttcaaaataa atcaaccatt agcgacgaaa ctaaaaaacg cgttcgcaag gcgatgaagg
    16021 agctcaatta ccaccccaac ctcaatgctc gtagcttggt aagcagctat actcaggtga
    16081 ttggtttggt tcttcctgat gactcagacg ccttctatca aaatcctttc ttcccatcag
    16141 tcctacgcgg catctctcaa gtcgcatctg aaaaccacta tgccattcag atagcaacag
    16201 ggaaagatga gaaggagcgt ctcaacgcta tttcacaaat ggtctacggc aagcgtgtag
    16261 atgggctaat ctttctctat gcccaagaag aagaccctct cgtaaaactc gtcgcagaag
    16321 aacagttccc cttccttatc ctaggtaaat ctctatctcc tttcatccca cttgtcgaca
    16381 acgacaatgt tcaagctggt tttgatgcga ctgaatattt catcaaaaaa ggctgcaaac
    16441 gcattgcctt tatcggagga agtaaaaagc tcttcgtgac caaagaccgt ttaacaggct
    16501 atgaacaggc gcttaaacat tacaaactta ccactgacaa caatcgcatc tactttgccg
    16561 acgagtttct ggaagaaaag ggctataaat ttagcaagcg attattcaag cacgatccac
    16621 aaattgatgc tatcatcaca accgatagcc tcctagctga aggtgtttgt aactatattg
    16681 ccaaacacca gctggatgtc cctgttctca gctttgactc ggttaatccc aagctcaact
    16741 tggcagccta tgtcgatatc aatagtttag agcttggtcg tgtttccctt gaaactattc
    16801 tccagattat taatgataat aaaaacaata aacaaatttg ttaccgtcaa ttgatcgccc
    16861 acaaaattat cgaaaaataa aagactgggc aaagagtcgt taaaagcaaa aacgcatact
    16921 atcaggtatt gaaaaaactt gatactatgc gttttattgt gggaagattt acttcctttt
    16981 ctactgaaat tgagtctttt cccaagatct ttttatactc aatgaaaatc aaagtgcaaa
    17041 ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat agaactgacg
    17101 aagtcagtaa ccatacctac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
    17161 agtattaatc actaattatc tatctcaaca aatcttccta gaatatgaac attttccgag
    17221 acagagacaa aggagcttgg atccacttgt gtcataatct gtttaaattc attaaactct
    17281 gcacgtgtaa tgacagtgat taaaactgcc tttctctcgt gattataggt tccttctgca
    17341 tcgtggatca tggttgctcc gcggtgcaat tttttatgga ttttttcaat taccttctct
    17401 ggatgatttg tcacaatcat ggcctgcata cgcttttgct tagtaaagac tgcgtctgtc
    17461 acacggctag agacaaagat ggtaatcata gaataaagag cgtatttcca accaaaggtc
    17521 aaacctgcta tcagcatgat agttccattt accaagaaag aaatactacc gacattctta
    17581 cccgttttct tgcgaatagt caggctgacg atatccgtcc caccactgga gatattgttt
    17641 cgaagagcaa aaccaatccc caaacccata acaacacccc caaaaaggga attgataatg
    17701 ggatcctccg tcaaggttgc cacagggaca aactggataa agaaggaact catagatacc
    17761 gtgataaagg taaagacggt gaacttatgg ccaatctgat accaagctaa gaccatcaaa
    17821 gggaagttaa tggcgtagaa gcttagcgaa atcggaatat gaaaaccaaa ccagtgatta
    17881 ctcaaggcag agataatctg tgccagacct gttgcaccac tcgaatacac atgccctggt
    17941 tggaaaaaga aattaactgc tactgctgat aaaaaaccat agaccagaga ggccgaaatc
    18001 ttctcatcat acttttctcg agagatactt tgtaagacac gtaaaatttt tatctgataa
    18061 gcaaagcggc gcagataata gcgccaccgc ttaattcgtt ttgtttgttt catcttcttc
    18121 tacttgtaag ctgagttcct ctagttgttt gagagcgact gttgatggag cttgtgtcat
    18181 tgggtcagtt gccttgttgt tcttaggaaa ggcaatgact tcacggatat tttcttctcc
    18241 agcaagcaac atgacaaagc ggtcaagccc gatagccaaa ccaccgtgtg gtgggaaacc
    18301 atagtccatg gcttcaagaa ggaaaccaaa ctggtcattg gcttcttcag ttgagaaacc
    18361 aagagccttg aacatgcgtt cttgaaggtc tttttggttg atacgaaggc taccaccacc
    18421 aagctcataa ccgttcaaga cgatatcgta agcaatggca cgaaccttag ccaaatcacc
    18481 ttctaattcg tgagcagtct cttcctgtgg aagtgtgaat ggatggtggg cgctcatgta
    18541 gcggccttct tcttcagacc attcaaacat cggccagtca accacccaaa ggaagttgaa
    18601 cttatcatta tcaatcaagc caagctcttt agcaatacgt ccacgaaggg cacccagtgt
    18661 tgcattagcc acttcaagcg tatccgccac aaagagaacc aagtccttat cttcaagagc
    18721 aagcgctgtt gtcaattctt cttggatacc agtcaagaac ttggcaactg gtccgtttaa
    18781 ttctccatca accaccttga cccaagcaag acctttggca ccatactgtt tggctacttc
    18841 cgtcatcttg tcgatgtctt tacgtgaata gttgtccgca gctcctttga ccacaatcgc
    18901 ttttacagca ggtgcttctg aaaagacttt aaagtctaca cctttgacca cttctgtcaa
    18961 gtcctgaagc aacatgtcaa aacgagtatc tggcttgtca gaaccgtaaa gagccatagc
    19021 atcatcgtat ttcatacgag ggaacggtag cgttacttcg atgccttttg tttccttcat
    19081 cacgcgcgcg atcaagcctt ctgtaatatc ttggatttct tgctcagtaa ggaaggacgt
    19141 ttccaagtcg acctgagtaa attcaggctg gcggtctcca cgcaagtcct cgtcacggaa
    19201 acatttaacg atttggtagt aacggtcaaa accagcattc atcaagagct gtttcgtgat
    19261 ttgtggactt tgaggaagag cgtaaaaatg ccccttatta acacgagacg gcactaaata
    19321 atcacgcgcc ccttcaggcg ttgacttaga aaggaatggt gtctccacgt cgataaactc
    19381 caactcatcc aaatagttgc ggatagagtg ggtcaccttg gcacgaagtt taagattttc
    19441 caacatttct ggacgacgaa ggtcaaggta acggtaacgc aaacgtgtat cgtcatttgc
    19501 ctcaatgcca tccttaatct caaatggtgt tgtcttagct gtgttaagca caataagagc
    19561 tgtcacgttt aactcaaccg caccagttgg caacttatca ttggcttgct cacgcgcagc
    19621 gacctgacca gtcacctcaa taacaaattc gctacgaagg ctttcagctg ttgccataac
    19681 ctctgcagat actttttcag ggttgataac caactgcatg attccttcac ggtcacgaag
    19741 atcgataaag atcaaaccac caaggtcacg acgacggcca acccatcctt tcaaggttat
    19801 ttcttgtccg atgtgttcct cacgaacacg accagcatac atactacgtt tcattatttc
    19861 tctcctcttt tattctgtta ctattttacc ataaaagcgc aggctcttca tgaaaatcat
    19921 cagaaaagtt tgccagtctt taaaagtcag gtgaaagccc taaaaattag cgctaatact
    19981 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtaggtatgg ttactgactt
    20041 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggtt agcttcctag
    20101 tttgctcttt gattttcatt gagtataata caaaaatccg atgaacttca ccggactctc
    20161 ttattttgaa tttttgcctg ctttacgctt ttcagcaatt tcggctgcct ttcgaggcaa
    20221 gacaatttcc gttatgtaag ccgtcccaaa acgcagtaca cctgcaatag gagcaaagac
    20281 aactgctaga tagttataga agaaatcgcc tttgaaggca taagctagcg ctccaatgat
    20341 gaaaaataga acaactgctt gaatcactgc taataaaatt actcgtttca tgtgacctcc
    20401 tgactctatt atagcatgag aatcatcaaa aagccgacta aattattcaa agcgtgaaga
    20461 gaaatactgt agaccagacc ttttctgcta acgtaagcca aacccaaact aaaaccaagg
    20521 ctaaaataga caaaaaattg ttgcacatca cctggaaaat gaatcaaggc aaatagaaga
    20581 ctagatacca gaagaaaaat cagggttcgt ttactattgt cctgcttagg aaagagatag
    20641 cgtgctaaca tccctctaaa aacaatctct tccgtcaaag gagcaaaaat aaccacagca
    20701 aaaaatgaga aaagtggttg agacaaggtc aagtctgtcg ctatttgttg atttactgaa
    20761 ggatcatctg gcaagaagaa ttgaacgacc agagataaga accaaatcaa ggcaggaagc
    20821 caaataaatc ggttaaagcc gatcttctca atatgaacag gagctttctg ataccatttg
    20881 taaatgccgt acacataaac tccagccaag gccacataaa gcaaggtaac agcatagggt
    20941 gaagccccta aggcaagcga agaggtcgcc agcccctgaa taaagccata gataaagaaa
    21001 aaggatagaa gggctagaag aaaccagcca aggtttttaa gtagtttcat agataactcc
    21061 tttatttgaa ataacgtttt accataggta actgcatcac attgatataa acatggatgg
    21121 ctcctacaag caagaaagct agtaactgaa tctctcctgt caagaaagaa atgataataa
    21181 gaaaaatata taaggctggt aagacatatt ggtgtaattg gaataaaatt cgaaaactct
    21241 gttccaaatt agcctgacgc tccccttcat cataagaatt tatatagttc aagatatcct
    21301 ttggtgtagc gaaaaattcc aaatcaaact gacgaacaat cgcaatggtt ttaaaaagat
    21361 atttttgagc gactaagaat accacaaaga gtaagaaaga aaggaaaaat gtttgagggt
    21421 ttatatgcaa tataatcacc tcacttaatg aaataaaaat agccaatgga atcgctacac
    21481 ctgtaatatt aaaagcaatg gttccaaact caagattccg atacatttgc acataatagg
    21541 tttcattcag atcatcatcc atttcctctt gatacaagga gtgaaatttt ctgcttttct
    21601 ttaggaaatt gaaagtcaaa agaatgctaa tgaaaactaa tactaaacaa atagctgata
    21661 tccatggtat caagattttt acatctaaaa taatttcgtg agattcgaca cgcgctttaa
    21721 acatccctac aaacatgccc aagaaacctc ccaagacaat agacatcaaa aataacaatc
    21781 tacgtctctt tttcatattc attctccttt ttcacttgct agatttttgg atttcttttc
    21841 aatccattca attactggga tgagagcaaa gtagacccaa acaaattggt cgctttgata
    21901 gggattaaac cagcttaggt ccatcccaat cagtagaaat acgctgactg ataaagctat
    21961 gaccactaca taataaatca ctttatactt gttcatcact cgtcctcctc caagcgaaat
    22021 accgattcga ctgtttcgtt gaaaatttga gatattttca gggcaatgat aatggacggg
    22081 gtgtactcat cccgttctag taggctaatg gtctgtctgg aaactcctgc cagcttggct
    22141 aggtcggttt gattgagacc atcgcgagct ctaagctctt ttagacgatt ttttagttgc
    22201 atgttacaca cctactctcc gtcaaattca acggtttgaa tatcctcaat acgttgcaac
    22261 ttgaattttt cttttcccgt attatctaca cgtcgtagct ttacccattc ctcatcaaca
    22321 tccacaactt cccagttatc tggcccaata tacactcccg ttataattgg ttcctttcca
    22381 atcatttctt gtaataatct cgacatttct gtgtttcctt tctcttttcg ctcaagtttt
    22441 ttgattttct tctctagttt cttgattttt ttagaattat tagaataaaa gaaaatcata
    22501 aatagtataa atactagtac ccacattata actcctttct gcttcctatt tcttaacttg
    22561 aattcattgt aacacctctt tttcttttta taaaagaaaa agaggctggg acaaaaatca
    22621 taaaaaggta tcctatcagg tgttcagaaa ccttggtagg atgcctttta taatggaaag
    22681 atttactgga ttttctcctc aaattgatac tcaatgaaaa tcaaaaccta aactaggaag
    22741 ctggctggat aggactgacc aagtcatcac agacctagag caaggcgacg ctgacctgat
    22801 ttgctccttg atttttgaag agtatagatt cttaaaatgg atagataaga caaaaaaaac
    22861 aaacaagacc gtattctgag tatcagaaaa ctcgtcttgt tcgtttttta tatttaaggt
    22921 tagactttta tcccaggttc ttagctctgt taggcaaggc tagaggggac agagggtctt
    22981 ttcccttaat cttctttacg acgacgtcct gctagaccaa gtcctaagat agcagtgctt
    23041 gctgctgcag ccagcaaggc tgttgaatca gcagttcctg tatttggcaa tgttttcttg
    23101 cttgtagcat ccttggtcgt ttctttagga gtcgatttcg cttgagtact tggagttgct
    23161 tggttagaag gtgtctcctg attagactta gtagacatag tcttaatagc aaacaagctg
    23221 aaatgattga ttctaaagat gacatgccca tcttctactt tagaatcaag aagttcgagt
    23281 tgaccatctg gtttcacatg gtagacttga acattctctc caagaccttc aagcgcaaga
    23341 cgaacagtcc gctcctcatt tacatgtgtt tccttgccat cttttgttaa ggataggtca
    23401 aataggcgaa tagatcctcc acctgcttgg cgactgatct tatcaacaag atccttttca
    23461 gtaatctcct tgacggtcac tttttctgca ttaaccggct tgtcaaataa gacggtcaca
    23521 tttacacttc caactgtgcc tgtaaaggtt tggtcgcctg cttgcggtgc ttgaggtgct
    23581 tgaggtgctt gttcaccagc tccgttgttg tcgcctgctt gcggtgcttg aggtgcttga
    23641 ggtacttgtt caccagctcc attgttgtcg cctgcttgcg gtgcttgagg tacttgttca
    23701 ccagctccgt tgttgtcgcc tgcttgaggt gcttgttcac cagctccgtt gttgtcgtct
    23761 tggccagcag ttaatgtttt ttgatattca gcaatataac catccatttc ctctttggct
    23821 tgttctacca agtcttccac tgctttttta tttggaaggc catcaagttg ttcacgatac
    23881 tcatctataa tgttttgaag ctttttcaga aggtctggaa aaccagaacc tgtttgatca
    23941 agttccttta aacgagtatc catatactgg ggcaaagtta ctttcgcttt ttctacagct
    24001 tcctcaattt ctttattctg aagattatcc aaagtgccct ctaattcaac caatttatca
    24061 agctctgtcg cagtatcaat ttggtttcta tatttctctt tttctccttc agttaaagat
    24121 aaccttccta acagatcatg caaggtcttt ctatagctat ctaaggttga ggatactcct
    24181 tgaggtctcg ctccatcagc agcctggact acttg
//
LOCUS       DAVFJR010000030        23791 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVFJR010000030 DAVFJR010000000
VERSION     DAVFJR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.031"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            396..4007
                     /locus_tag="VU722_001504"
     CDS             396..4007
                     /locus_tag="VU722_001504"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU1772449.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHA
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVVMSERLVKDDIYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEDAEKATKAEATEEAAEQE"
     gene            4041..7718
                     /gene="rpoC"
                     /locus_tag="VU722_001505"
     CDS             4041..7718
                     /gene="rpoC"
                     /locus_tag="VU722_001505"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU1772450.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKVL
                     FNDIMPEGLPYLQEPNNGNLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYQHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIADQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            7819..8232
                     /gene="ndk"
                     /locus_tag="VU722_001506"
     CDS             7819..8232
                     /gene="ndk"
                     /locus_tag="VU722_001506"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU1772451.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGTKVIEIWRTMMGATRPEEALPGTI
                     RGDFAKAAEENEVIQNVVHGSDSEESAKREIALWF"
     gene            8466..8689
                     /gene="tnpA"
                     /locus_tag="VU722_001507"
                     /pseudo
     CDS             8466..8689
                     /gene="tnpA"
                     /locus_tag="VU722_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            8793..8993
                     /gene="tnpA"
                     /locus_tag="VU722_001508"
                     /pseudo
     CDS             8793..8993
                     /gene="tnpA"
                     /locus_tag="VU722_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            9597..10217
                     /locus_tag="VU722_001509"
     CDS             9597..10217
                     /locus_tag="VU722_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772452.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF"
     gene            10303..10746
                     /gene="tsaE"
                     /locus_tag="VU722_001510"
     CDS             10303..10746
                     /gene="tsaE"
                     /locus_tag="VU722_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU1772453.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDTYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            10736..11254
                     /locus_tag="VU722_001511"
     CDS             10736..11254
                     /locus_tag="VU722_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772454.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            11262..12278
                     /locus_tag="VU722_001512"
     CDS             11262..12278
                     /locus_tag="VU722_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU1772455.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGVELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRVHMLEMQNILRRSLGQEEVTQLETNVVLFEDLFGRAPVG
                     DEDN"
     gene            12362..13618
                     /locus_tag="VU722_001513"
     CDS             12362..13618
                     /locus_tag="VU722_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU1772456.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGVSLTGVAGPDSLEGHPVGTVFIGLAQEQETEVINVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            13673..14839
                     /gene="recA"
                     /locus_tag="VU722_001514"
     CDS             13673..14839
                     /gene="recA"
                     /locus_tag="VU722_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU1772457.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEASEQDIENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            15164..16534
                     /locus_tag="VU722_001515"
                     /pseudo
     CDS             15164..16534
                     /locus_tag="VU722_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
     gene            16910..17866
                     /gene="lytA"
                     /locus_tag="VU722_001516"
     CDS             16910..17866
                     /gene="lytA"
                     /locus_tag="VU722_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU1772458.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKVNDTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            18231..18391
                     /locus_tag="VU722_001517"
                     /pseudo
     CDS             18231..18391
                     /locus_tag="VU722_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18605..18988
                     /locus_tag="VU722_001518"
     CDS             18605..18988
                     /locus_tag="VU722_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772459.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            18998..19369
                     /locus_tag="VU722_001519"
     CDS             18998..19369
                     /locus_tag="VU722_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772460.1"
                     /translation="MTEQLLEKLYSGKIVIPQEVYDEINIPTIPHLKSRIDQLVTKGS
                     AEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLAKKHNGILGSNNLRDVKPY
                     VEEFSLEHMTTGDILVEAFKA"
     gene            19778..20773
                     /locus_tag="VU722_001520"
     CDS             19778..20773
                     /locus_tag="VU722_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772461.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELALTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMNVVLVFSKLSDSEKKQLLQARIPFVDFKG
                     NLFFPTLGLVLNADDTEVPKELTPSEQLTWIAFLLTKDQKVVDVELLSRVTGLPNSTI
                     YRCLRTFKALDWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGTYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHALEGKVLEIWKYCPF
                     ISEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEVLENMILQYLGDDDAS"
     gene            20763..21242
                     /locus_tag="VU722_001521"
                     /pseudo
     CDS             20763..21242
                     /locus_tag="VU722_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21364..21624
                     /locus_tag="VU722_001522"
     CDS             21364..21624
                     /locus_tag="VU722_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772462.1"
                     /translation="MRERSATGAQGLSKFIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTIPQNDDISLDQNEIFQILKNFLDG"
     gene            22160..23098
                     /locus_tag="VU722_001523"
                     /pseudo
     CDS             22160..23098
                     /locus_tag="VU722_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23283..23682)
                     /locus_tag="VU722_001524"
                     /pseudo
     CDS             complement(23283..23682)
                     /locus_tag="VU722_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7311 a         4280 c         5286 g         6914 t
ORIGIN      
        1 ttgaaaatga ttttcagtca atagtttttt cagttttttg taccatagcg tgattcgaat
       61 gtgatgccaa gttttctatg ggaaaaaaat taccaaaaac ctactgaatt cccttgaaaa
      121 atctagctaa atagggtata atatgggtaa tcatttgtcg taggttttgt ctgaaatatt
      181 gtccagacaa ggctcacagc agttaaatct tctgaaaaag tcagatttag ctgctctttt
      241 tgtgcttttt ttcaagattt tgagcatttg taacagaggc ttaaagattc tgaaaattcg
      301 tcaagaggac acggtgataa ggggtttaca accatatggc gattagaaaa gcctgattga
      361 caaggcttgg aacttattta caaaggagaa tcatcttggc aggacatgac gttcaatacg
      421 ggaaacatcg tacccgtcgt agtttttcaa gaatcaaaga agttcttgac ttaccaaatt
      481 tgattgaaat tcaaactgac tcattcaaag ctttcctaga ccacgctctt aaggaagtgt
      541 ttgaagatgt attgccaatt tcaaacttca cagacacaat ggagttggaa tttgttggat
      601 atgaaatcaa ggaaccaaaa tacacgctag aagaagctcg tatccacgat gctagctact
      661 cagcaccaat ttttgtaacc ttccgcttga tcaataaaga aacaggcgaa atcaagaccc
      721 aagaagtttt ctttggtgat ttcccaatca tgacagaaat gggtactttc atcatcaatg
      781 gtggtgaacg tattatcgtt tctcagttgg tccgctcacc aggtgtttac tttaacgaca
      841 aagtagacaa aaatggtaag gtgggctatg gttcaactgt tatccctaac cgtggagctt
      901 ggttggaact tgaaagcgac tcaaaagata tcacctacac tcgtatcgac cgtactcgta
      961 agattccatt tacaaccttg gttcgtgctc ttggtttctc aggtgatgat gaaatctttg
     1021 atatctttgg tgacagcgaa ttggttcgca acactgttga aaaagatatc cacaagaatc
     1081 caatggactc tcgtacagac gaagccttga aagaaattta cgaacgcctt cgtccaggtg
     1141 agcctaagac agctgaaagc tcacgtagct tgcttgtggc tcgcttcttt gacccacgtc
     1201 gctatgactt ggcagcagtt ggtcgttaca aaatcaataa aaaactcaat gttaaaacac
     1261 gtttgctcaa ccaaaccatt gcagagccat tggtagaccc tgaaactgga gaaatcttgg
     1321 tagaagctgg tacgattatg actcgtagcg tgattgaaag tattgaaagc catttggatg
     1381 gcgacttgaa caagattgtc tacatcccaa acgatgcagc cgttgtgact gagcctgttg
     1441 ttcttcaaaa attcaaggtt gttgctccaa ctgatccaga tcgcgtcgta acgatcattg
     1501 gtaatgctaa cccagatgac aaggttcgta cggtgactcc tgcagatatc cttgctgaga
     1561 tgagctactt cctcaacttg gctgaaggac ttggccgtgt agatgatatc gaccaccttg
     1621 gaaatcgtcg tatccgtgcg gttggtgaat tgcttgccaa ccaagtacgt ttgggacttt
     1681 ctcgtatgga acgtaatgtc cgtgaacgta tgtctgttca ggacaatgaa gtcttgacac
     1741 cacaacaaat tatcaatatc cgtcctgtaa cagctgcagt taaagaattc tttggttcat
     1801 cacagttgtc acagttcatg gaccaacaca acccgctttc tgagttgtct cacaaacgcc
     1861 gtttgtcagc cttaggacct ggtggtttga ctcgtgaccg tgccggatat gaagtacgtg
     1921 acgtgcacta cactcactat ggtcgtatgt gtccaatcga gacacctgaa ggacctaaca
     1981 tcggtttgat caataacttg tcatcttacg gacacttgaa caaatatggt tttgttcaaa
     2041 caccataccg taaggttgac cgtgaaacag gtgttgtcac gaacgaaatt gtttggttga
     2101 cagctgatga agaagatgaa tatactgtag ctcaggctaa ctctcgtctg aatgaagatg
     2161 gaacctttgc tgagaagatt gtcatgggac gtcaccaagg ggtcaaccaa gagtatccag
     2221 ctaatattgt tgactacatg gacgtttcac caaaacaggt agttgccgtt gcgacagcat
     2281 gtattccttt cttggaaaac gatgactcca accgtgccct catgggagcc aatatgcaac
     2341 gtcaggctgt gccattgatt aatcctcagg caccttacgt tggtactggt atggaatacc
     2401 aagcagccca cgattctggt gcggctgtga ttgctcagta tgatggtaaa gttacttacg
     2461 cagatgctga caaggtagaa gttcgtcgtg aagatggttc attggatgtt taccacatcc
     2521 aaaaattccg tcgttcaaac tcaggtactg cttacaacca acgcactctc gtaaaagttg
     2581 gtgatgtcgt tgaaaaaggc gatttcatcg ctgacggacc ttctatggaa aatggagaaa
     2641 tggcgcttgg acaaaaccca atcgttgcct acatgacttg ggaaggttac aacttcgagg
     2701 atgccgttgt catgagcgaa cgcttggtga aggacgatat ctacacatct gttcaccttg
     2761 aagaatacga atcagaaacg cgcgatacaa agcttgggcc tgaagaaatc actcgcgaaa
     2821 ttccaaacgt tggtgaagat gccctcaaag accttgacga aatggggatt atccgtattg
     2881 gtgctgaggt taaagaaggt gatattcttg taggtaaagt aacacctaag ggtgagaaag
     2941 acctttcagc tgaagaacgt ctcttgcacg ctatctttgg agacaagtct cgtgaagtgc
     3001 gtgatacttc tcttcgtgta ccacacggtg ccgatggtgt cgttcgtgat gttaagatct
     3061 ttacacgtgt aaatggagat gagttgcaat caggtgttaa catgttggtt cgtgtttaca
     3121 tcgctcaaaa acgtaagatt aaggtcggag ataaaatggc cggacgtcac ggaaacaaag
     3181 gggttgtctc tcgtatcgtt cctgtagaag acatgcctta ccttccagac ggaactccag
     3241 tcgacatcat gttgaatcca cttggggtgc catcacgtat gaatatcggt caggttatgg
     3301 agcttcacct tggtatggca gctcgtactc ttggtattca catcgcgaca ccagtctttg
     3361 atggagcaag ttctgaagat ctttggtcaa ctgttaaaga agcaggtatg gatagcgatg
     3421 ccaagacaat cctttacgat ggacgtacag gtgaaccatt tgataaccgt gtttctgttg
     3481 gagtcatgta catgatcaaa cttcaccaca tggttgacga taaattgcac gcgcgttcag
     3541 tcggacctta ctcaactgtt acccaacaac cactcggagg taaagctcag tttggtggac
     3601 aacgtttcgg tgagatggag gtttgggctc ttgaagccta cggtgcgtca aatgtccttc
     3661 aagaaatctt gacttacaag tctgacgata tcaacggacg tttgaaagcc tatgaagcta
     3721 ttacaaaagg caaaccaatt ccaaaaccag gtgttccaga atccttccga gttcttgtca
     3781 aagaattgca atctcttggt cttgacatgc gtgtcctaga cgaagatgac caagaagtgg
     3841 aacttcgcga cttggatgaa ggaatggacg aagatgtcat ccacgtagat gaccttgaaa
     3901 aagcccgtga aaaagcagcc caagaggcta aagcagcctt tgaagctgaa gacgctgaga
     3961 aagcaacaaa agcggaagca acagaagaag ctgctgaaca agaataagca gttcacttac
     4021 gaatagaaag ggaagaaata gtggttgatg taaatcgttt taaaagtatg caaatcaccc
     4081 tagcttctcc aagtaaagtc cgttcatggt cttatggaga agtcaaaaaa cctgaaacaa
     4141 tcaattatcg taccttgaaa ccagaacgtg aaggactctt tgatgaagtg atctttggtc
     4201 ctacaaaaga ctgggaatgt gcttgtggta agtacaaacg cattcgttac agaggaattg
     4261 tttgtgaccg ctgtggggtt gaagtaacgc gtacgaaagt tcgtcgtgag cgtatgggac
     4321 atatcgaatt gaaagctcct gtatctcaca tctggtactt caaggggatt ccaagccgta
     4381 tgggcttgac ccttgatatg agccctcgtg ccctcgagga agttatctac tttgcggctt
     4441 atgtggtgat tgatcctaag gatacaccac ttgagcacaa gtctatcatg acagagcgcg
     4501 aataccgaga gcgcttgcgc gaatatggtt atggttcatt tgttgccaag atgggtgccg
     4561 aagccatcca agaccttttg aagcaagtag atcttgaaaa agaaattgct gaactcaaag
     4621 aagaattgaa aacagctacc ggacaaaaac gtgttaaagc catccgtcgt ttggatgttt
     4681 tggatgcctt ttacaagtct ggaaacaaac ctgaatggat gatccttaac atccttccgg
     4741 ttatcccacc agatcttcgt ccaatgttgc agttggatgg tggccgtttt gcctcatctg
     4801 acttgaatga cctttaccgc cgtgttatca accgtaacaa ccgtttggct cgtttgcttg
     4861 agttaaatgc accaggtatc atcgttcaaa atgagaagcg tatgcttcaa gaagcggttg
     4921 acgctttgat tgacaatggt cgccgtggtc gtccaatcac agggccaggt agccgtccat
     4981 tgaaatcatt gagccacatg cttaaaggta aacaaggacg cttccgtcaa aacttgctcg
     5041 gtaaacgtgt tgacttctca ggacgttccg ttatcgccgt tggtccaact cttaagatgt
     5101 accaatgtgg tgtgccgcgt gaaatggcga ttgaactctt taaaccattt gtcatgcgtg
     5161 aaatcgttgc ccgtgatatc gtgcaaaacg tcaaagcagc taaacgcttg gtggaacgcg
     5221 gagatgagcg tatctgggat atccttgaag aagtgattaa agaacaccca gtgcttttga
     5281 accgcgcacc gacccttcac cgtttgggta tccaagcctt cgagccagtc ttgattgatg
     5341 gtaaggctct tcgcttgcac ccacttgtct gtgaagccta caatgccgac tttgacgggg
     5401 accaaatggc catccacgta ccactttcag aagaagcaca agcagaagct cgtatcctca
     5461 tgctagctgc tgagcacatc ttgaacccga aagatgggaa accggtagtt actccatctc
     5521 aggacatggt tttgggtaac tactacttga ccatggaaga agctggtcgg gaaggcgaag
     5581 gaatggtctt caaagatcgt gacgaagcgg ttatggctta ccgcaatggt tatgttcacc
     5641 tccactcacg tgttggtatc gcaacagaca gcctcaacaa gccttggaca gaagagcaaa
     5701 gacataaggt cttgcttaca acagttggta aagttctctt caacgatatc atgccagagg
     5761 ggctaccata cttgcaagaa ccaaacaatg gcaacttgac agaaggtgtt ccagctaaat
     5821 acttcttgcc acttggtgga gatatcaagg aagctatcag caatcttgaa ctcaaccctc
     5881 cattcaagaa gaaaaacctt ggaaatatca tcgctgaaat cttcaaacgt ttccgtacga
     5941 cagaaacttc tgccctactt gaccgcatga agaacctcgg ttaccagcac tcaactcttg
     6001 caggattgac agtgggtatt gccgatatcc cagtcgttga tgacaaggct gaaatcattg
     6061 aagaatcaca caaacgtgtc gaacaaatca ccaaacaatt ccgtcgtggt atgatcacag
     6121 acgacgagcg ttacaatgct gttacagctg aatggcgtgc tgcccgtgaa aaacttgaga
     6181 aacgcttgat tgctgaccaa gatcctaaga acccaatcgt tatgatgatg gactctggag
     6241 cccgtggtaa catctcaaac ttctcacagc ttgccggtat gcgtggtctg atggctgctc
     6301 cgaatggacg tatcatggaa ttgccaatcc tttcaaactt ccgcgaaggt ttgtcggtat
     6361 tggaaatgtt cttctcaact cacggtgctc gtaaaggtat gaccgatacg gcccttaaga
     6421 cagccgactc aggttacttg actcgtcgtt tggtcgacgt tgcccaagac gttatcatcc
     6481 gtgaggacga ctgtggaact gaccgtggtc tcttgatccg ttctatcgca gaaggaaaag
     6541 agatgatcga gtctctcgaa gagcgtctca acggtcgtta cactaagaaa actgttaaac
     6601 atccagaaac tggtgcagtg attattggtc caaatgaatt gattacagaa gacaaggcgc
     6661 gtgaaattgt caatgctggt gtggaagaag tgactatccg ttctgtattt acatgtaaca
     6721 ctcgtcacgg tgtctgccgt cactgttacg gtatcaactt ggcgactggt gatgcggttg
     6781 aagttggtga agcagttggt acaatcgctg cccaatctat cggggaacct ggtacacagc
     6841 ttacaatgcg taccttccac acaggtgggg ttgcctcaaa taccgatatc actcagggtc
     6901 ttcctcgtgt ccaagaaatc tttgaagccc gcaatcctaa aggggaagcg gttatcacag
     6961 aggttaaagg acaagttact gctatcgaag aagatgcatc aactcgtacc aagaaagtct
     7021 ttgttaaggg tgaaactggc gaaggtgaat atgtcgttcc atttacagct cgtatgcgtg
     7081 tcgaagttgg gggccaagta gcgcgtggtg ctgctctgac agaaggttct atccaaccaa
     7141 aacgtctcct tgcagttcgt gatgtcttgt cagttgaaac gtaccttctc ggtgaagtac
     7201 aaaaagttta ccgtagccaa ggggtagaaa tcggtgacaa acacatcgag gtaatggttc
     7261 gtcaaatgat ccgtaaagtc cgtgtcatgg atccaggtga tacagatctt ctcatgggta
     7321 ccctcatgga tatcaatgac tttacagatg ccaacaaaga tgtccttatc gcaggtggag
     7381 ttccagcgac aggtcgccca gtccttatgg gaattaccaa agcctcactt gaaacaaaca
     7441 gtttcttgtc agcggcttcc ttccaggaaa caactcgtgt ccttactgac gcagctatcc
     7501 gtggtaagaa agaccatctc cttggactta aagaaaatgt tatcatcggt aagatcatcc
     7561 cagctggtac tggtatggcc cgttaccgta accttgaacc acatgctgtc aacgaagaag
     7621 aataccttaa tcctccagta gaggaagaag gaaatgaaga aacaacagaa gtagttgtgg
     7681 atactgccgt tgaaactgtg gaagaaacag tagaataaga gaaccctcgg gttctctcat
     7741 tctctcttct gaaaactttc tccatttttc cacgaaatgt ggtaaaataa aagaaagaag
     7801 ctgacaaagg agacgagtat ggaacaaaca ttctttatca tcaaaccaga tggtgtaaaa
     7861 agaggactag tgggtgaagt gttaaagcgc atcgaacaac gtggatttac aatcgaaaaa
     7921 ttggagtttc gttcacaggt ttcagaagag ttgattgacc agcactatca ggacttggtt
     7981 ggtcagagtt tttacccacc gattcgtgaa ttcatgactt caggtccagt tcttgtgggt
     8041 gtcatttctg gtaccaaagt aatcgaaatt tggcggacca tgatgggtgc aactcgtcca
     8101 gaagaagctt taccaggcac tattcgaggt gattttgcaa aagctgctga agaaaatgag
     8161 gttatccaaa atgttgtaca tggttcagat tcagaagagt cagctaagcg agaaattgct
     8221 ctttggtttt aagagtggat tggctcaatc aattggttaa aagctcattt gaatagaaag
     8281 tatagtcaat tagtttaaga catgacgcat gatatcaaac tttttaggtt ttgatatggt
     8341 gcgttttttg attaagtgac tattagttcg tctcgctccg ttaggtgcga gacaaaacaa
     8401 ccacccgcta tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa
     8461 taaaggtgtt caagccaatt ataaagcgaa aggagaaaaa tatggcacaa aaagcacata
     8521 gtttatcata cacaaagtgg atgtgttcta tcacattgtg ttcaccccta ggtatagacg
     8581 aacagtcatt tataatcaat atcgaagtag tttgggagaa atatttcatc gcttgtgtag
     8641 ttataaaggt gttgaaatta tcgagggtca cttaatgcct gaacatgtat agtgaattga
     8701 aataagatgt gaacatcctc tatcaggaaa gtcaaattaa tttatagaaa tattttagca
     8761 gtcaagatgt actgttatag cttcaataca ctatacatat gttagtcagt attccgccga
     8821 ggctaagtgt ttcaagtttt atggggtgtt taaaaggcaa aagtgcactc atgatgtttg
     8881 acaaacatgc caatctcaag tacaagtttg ggaatcggca tttctgggcg gaaggttatt
     8941 atgtgagcac agtagggctt aacaaagcca caattaagaa gtatagtcaa gattaaagaa
     9001 attatcgagt ggatgatttc ttcacgagta tgaaaatttg agaacgagta aagcatgata
     9061 tatagtaaaa tgaaataaga acaggacaaa attgatcagg acagtcaaat cgatttttaa
     9121 caatgtttta gaagtagagg tgtactattc cagtttgaat ctactatagc actagataaa
     9181 ttgagtgtaa aagaatatga ggctcccttt agggatagtg gtaagtaata ctaaagcctc
     9241 ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtgaa agccagcgcc
     9301 taaagacgct ggctgatgat ttgggcttat agctctagga taaaccaccc gtttgacgga
     9361 ttttcatgat ttcaaattta tattcttcaa aaatctcttc aaaccacgtc agctctatct
     9421 gcaatctcaa aacagtgttt tgagcaacct gtggctagct acctagtttg ctctttgatt
     9481 tttattgagt attagtctct agtgtttgtt tagcgtctta aagagacatt tgagaagatt
     9541 agaaacagtt ctctcttttc tcctagtata atgattggta ggaagggaga gagaagatga
     9601 aatcaatgag aatcttattt ttgttagctt taattcaaat cagtttgagt agctgtttcc
     9661 tatggaagga atgcatcttg tcctttaaac aaagtacagc ttttttcatc ggaagcatgg
     9721 ttttcgtttc aggaatctgt gctggagtaa attatcttta tacccgtaag caagaagtcc
     9781 atagtgtcct agccagtaag aagtcggtga agctttttta tagtatgtta ctcttaatta
     9841 atttgttagg agctgttctt gttttgtcag ataacttgtt catcaaaaat acgctgcagc
     9901 aagaattagt tgacttttta ttgccatcct tctttttcct atttggacta gatttgctga
     9961 tttttttacc cttgaaaaaa tacgtgcgcg attttcttgc tatgctagac agaaaaaaga
    10021 cagtgttggt gactatttta gcaacacttc ttttcttaag aaatccaatg accattgtct
    10081 cacttctgat ttatattgga ctgggcttgt tttttgcagc ctatcttgtc ccaaattcgg
    10141 ttaagaagga agtttccttt tatggtcata ttttccgaga tcttgtattg gtcattgcta
    10201 cgctcatttt cttttagaga aagcctgttt tttatggatg ttatgatgat aagtttagta
    10261 ggaaaataga cacaaaagaa aagtttttgg tataataaga gtatgtacac aaaaaatgaa
    10321 gaagagttgc aagccttagg ggagcgtttg ggccatctat tagcaaagaa tgatgtttta
    10381 atcttaactg gagaactggg tgcaggtaaa acgaccttta ctaaaggact tgcaaaagga
    10441 ttacagattt ctcaaatgat taaaagtccc acctatacta tcgtgagaga gtatgaaggt
    10501 cgacttccac tttatcacct agatgtttat cgtattgaag gagatgctga ttctatcgac
    10561 ttggatgagt ttatctttgg tggtggcgtg actgttattg agtggggaaa tctcttagga
    10621 gatgccttgc cagatactta tttagaattg gaaattctaa aagaagcaga tggacgccgt
    10681 ttaaattttc aggcaaaggg tttgcgtgct gagaaattgt tagaggagct tcaatatgga
    10741 gtatgaattg ctcattaggg aagcagagcc caaagatgca gctgaattag tggccttttt
    10801 aaatcgtgtg agtttggaga cagactttac cagcctagac ggagatggta ttctcttgac
    10861 tagtgaggag atggaaatat tcctcaacaa gcaagctagt tcggacaatc agataacctt
    10921 acttgcattc ttaaatggca aaattgctgg tattgtaaat attacagctg accagcgtaa
    10981 gagagtccgt catattggag atctcttcat tgtgattgga aaaagatatt ggaataatgg
    11041 cttgggaagt ttgttgctag aagaagcgat agagtgggca caagcaagtg gcattctgcg
    11101 tcgtctccaa ctgactgtcc aaactcgtaa tcaagcagca gtccatcttt atcaaaagca
    11161 tggctttgtc attgaaggta gccaagagcg tggggcatat atagaagaag ggaaatttat
    11221 cgatgtttac ttgatgggta aactgatagg ttagtagaaa tatggttaaa aaaattattg
    11281 gaatggtgct agctttactt tctgtaactg tagtaggagt aggtgttttt gcttatacta
    11341 tttatcaaca agggacagaa accttagcta aaacctataa aaaaatcggc gaagaaacca
    11401 aggttattga agcgactgaa cctctaacca ttctgttaat gggagtggac accggaaatg
    11461 ctgaacgaac tgaaacttgg gtcggtagaa gtgatagcat gatcttgatg acagtgaatc
    11521 ctaaaacgaa aaaaacaaca atgatgagtt tagagcggga cattctgacg cgcattgaat
    11581 cagggaatgg tcaggctcat gaagcgaaac tgaactcagc atatgcagat ggtggagtag
    11641 agcttgctat agaaaccatt caaaaaatga tgaatatcca tattgatcgc tatgtaatgg
    11701 tcaatatgag agggttgcaa aaactagtgg atgcagtagg aggtattaca gtcaataata
    11761 tcctaggttt cccaatttct atcagtgacc aagaagaatt taatactatt tctatcggtg
    11821 ttggggagca acatattggg ggagaagaag ccctagtcta tgcacgaatg cgttaccaag
    11881 atcctgaggg ggattatggt cgtcaaaaac gtcaacgtga agttattcaa aaagtcatgg
    11941 aaaaagctct cagtttaaat agcgttggtc attatcaaga gattctaaaa gctttgagtg
    12001 acaatatgca gaccaatatt gatttgtctg caaaaagtat ccctaacttg ctaggctata
    12061 aagattcatt taaaaccatt gaaactcagc agttgcaggg tgaaggagag atacttcaag
    12121 gtgtttctta ccagattgtt tcaagagtac atatgttgga aatgcaaaat atactccgac
    12181 gttctttggg acaagaagaa gttactcagc ttgaaaccaa tgtggtttta tttgaagatt
    12241 tatttggcag agcacctgtt ggtgatgaag ataattaact tttgatacaa ataaaaaatc
    12301 aatcgtagga aaattcctgc gattttttca aaaaaatacg aatagatagg taggaggaaa
    12361 tatgaaagca gaaatcattg ctgttggaac agagattttg acaggacaga ttgtcaacac
    12421 caatgcccag tttttgtcgg aaaaactagc tgagattggg gtagatgtat attttcagac
    12481 agctgtagga gacaatgaag ttcgtctctt gtctttgctt gagattgcca gtcaacgtag
    12541 cagtctggtg attttgacag gcggtttggg gccaactgag gacgacctaa ccaaacaaac
    12601 cctagctaaa tttttaggga aagcattagt ctttgatcct caggctcagg agaagttgga
    12661 tatctttttt gccctgcgac cagactatgc ccgaacaccg aataacgaaa gacaagctca
    12721 aattgtagaa ggagcgattc cactgccaaa cgaaacagga ctggctgttg gaggaaaatt
    12781 agaagtagac ggagtgacct atgtcgtcct tccaggtccg ccaagtgaat tgaaacccat
    12841 ggtcttaaac caacttctac ccaagttgat gacagggagc aagctgtatt cccgagttct
    12901 tcgtttcttt gggattggcg agagccagct ggttacgatt ttggctgatt taattgataa
    12961 tcagatcgat cctaccttgg ccccttatgc caagacagga gaagtcactc tacgtctgtc
    13021 aacaaaggct agcagtcaag aagaggcgaa tcaagcgctg gatatcttgg aaaatcaaat
    13081 cttggactgc cagactttcg aaggaatttc tttacgagac ttttgctatg gttatgggga
    13141 agaaactagt ttagccagca ttgtggtaga agaactgaaa aggcaaggga aaaccatcgc
    13201 ggctgcagag agtttgacgg caggtctttt ccaagctacc gtggcgaatt tttctggagc
    13261 ttcaagtata tttaagggtg gttttgtgac ctatagcttg gaggaaaaat caaggatgtt
    13321 ggatattcct gccaagaatt tggaagaaca tggtgtggtg tctgaattta cagctcagaa
    13381 gatggctgag caggcacgaa gcaagaccca gtctgatttt ggagttagtt tgactggagt
    13441 ggcaggacca gatagcctag aaggacaccc agttgggaca gtcttcatag gcttggcgca
    13501 agagcaagaa actgaggtta tcaatgttaa tattggaggc agaagccgag cagatgtacg
    13561 tcatattgcg gttatgcatg cctttaacct agttcgcaag gctttattaa gtgactaact
    13621 tttgatataa tagtagatag gtctgaggaa cattagaatg taggagaata gaatggcgaa
    13681 aaaaccaaaa aaattagaag aaatttcaaa aaaatttggg gcagaacgtg aaaaggcctt
    13741 gaatgacgct cttaaattga ttgagaaaga ctttggtaaa ggatcaatca tgcgtttggg
    13801 tgaacgtgcg gagcaaaagg tgcaagtgat gagctcaggt tctttagctc ttgacattgc
    13861 ccttggctca ggtggttatc ctaagggacg tatcatcgaa atctatggcc cagagtcatc
    13921 tggtaagaca acggttgccc ttcatgcagt tgcacaagcg caaaaagaag gtgggattgc
    13981 tgcctttatc gatgcggaac atgcccttga tccagcttat gctgcggccc ttggtgtcaa
    14041 tattgacgaa ttgctcttgt ctcaaccaga ctcaggagag caaggtcttg aaattgcggg
    14101 aaaattgatt gactcaggtg cagttgatct tgtcgtagtc gactcagttg ctgcccttgt
    14161 tcctcgtgcg gaaattgatg gagatatcgg agatagccat gttggtttgc aggctcgtat
    14221 gatgagccag gccatgcgta aacttggcgc ctctatcaat aaaaccaaaa caattgccat
    14281 ttttatcaac caattgcgtg aaaaagttgg agtgatgttt ggaaatccag aaacaacacc
    14341 gggcggacgt gctttgaaat tctatgcttc agtccgcttg gatgttcgtg gtaatacaca
    14401 aattaaggga actggtgacc aaaaagaaac caatgtcggt aaagaaacta agattaaggt
    14461 tgtaaaaaat aaggtagctc caccgtttaa ggaagccgta gttgaaatta tgtacggaga
    14521 aggaatttct aagactggtg agcttttgaa gattgcaagc gatttggata ttatcaaaaa
    14581 agcaggggct tggtattctt acaaagatga aaaaattggg caaggttctg agaatgctaa
    14641 gaaatacttg gcggagcacc cagaaatctt tgatgaaatt gataagcaag tccgttctaa
    14701 atttggcttg attgatggag aagaagcttc agaacaagat attgaaaaca aaaaagatga
    14761 gccaaagaaa gaagaagcag tgaatgaaga agttacgctt gacctaggcg atgaacttga
    14821 aattgaaatt gaagaataag ctgttaaagt agtggagaaa tccgctactt tttcgatttt
    14881 tgattcaagt ttttagatta tatatagtag attgaaataa gatatgaaca actctattag
    14941 gaaagtcaaa ttaatttcta gaaatatttt agcagctaca gcttactatt ccaaactcaa
    15001 ccaactataa tagatcgaaa ctagaatagt acacatctac ttctaaaaca ttgttaaaaa
    15061 tcgatttgac tgtcctgatt gatttatcct gtttttattt cattttgcta tatatagttt
    15121 gctgtttctt gtcgctcctc tagaaagttg atataatagc tttatgaata aacaacgaac
    15181 agtggacctg atacatggtt cgattcttcc ctcgttctta agcttcacct tcccaatctt
    15241 gctatcaaat atttttcaac agctctataa cactgctgat gtcttgattg ttggacgatt
    15301 tcttggtcaa gaatccttgg ctgcagtagg agcgacgaca gcgatttttg acctgattgt
    15361 aggttttaca cttggtgttg gcaatggcat ggggattgtc attgctcgtt attatggggc
    15421 tcggaatttc actaaaatca aggaagcagt agcagccact tagattttag gtgctctttt
    15481 gagcattcta gttatgttgc tgggctttct tggcttgtat cctctcttgc aatacttaga
    15541 tactcctgca gaaattcttc ctcaatctta tcaatatatt tctatgattg tgacctgtgt
    15601 aggtgtcagc tttgcttata atctttttac aggcttgttg cggtctattg gtgacagtct
    15661 agcagccctg ggatttctga ttttctctga cttggttaat gtggttctag atctctattt
    15721 tattacgcaa ttgcatctgg gagttcaatc tgcaggactt gctaccatta tttcgcaagg
    15781 tttatcagcg gttctctgct tttattatat tcgtaaaagt gtgccagaac tcttgccaca
    15841 gtttaaacat ttcaaatggg acgaaagctt gtacgcggat ctcttggagc aaggtttggc
    15901 tatgggcttg atgagttcaa ttgtatctat cggcagtgta attttacagt cttctgttaa
    15961 tacctttggt gcagtgatta ttagtgccca gacggcagct cgacgcatta tggtctttgc
    16021 ccttcttcct atgaccgcta tttctgcatc aatgactacc tttgcttctc agaatcgagg
    16081 agctaagcga cctgaccgca ttgctcaagg tcttcgaatc ggtagtcgtt taagtatatc
    16141 ctgggcagtt tttgtttgta ttttcctctt ttttgccagt ccagccttgg tttccttctt
    16201 ggctagttcg acagatggtt acttgataga aaatggaagt ctctatctgc aaatcagttc
    16261 agccttttat cccattttga gcctcttgtt gatttatcgc aattgcttgc agggcttggg
    16321 gcaaaagatc cttcctctag tttctagctt tattgaacta atcggaaaaa tcgtttttgt
    16381 ggttttgatt attcattggg caggatataa gggtgttatc ctttgtgaac ctcttatctg
    16441 ggttgccatg acagttcaac tgtacttctc actattctgt catcccttga taaaagaagg
    16501 caaggcaatc ttggcaacca aagtgcaatc ctagttggat ttactgaata aaatccattt
    16561 cctctagtga gaatcgaaaa aacttgtgtt ctcctcttta gtttggtgtt gaaaatagtt
    16621 taacagactt ttgacttctt ttatatgata taataaagta tagcatttat gaaaaggaca
    16681 tatagagact gtaaaaatat acttttgaaa agctttttag tctggggtgt tattgtagat
    16741 agaatgcaga ccttgtcagt cctatttaca gtgtcaaaat agtgcgtttt gaggttctat
    16801 ctacaagcct aatcgtgact aagattgtct tctttgtaag gtagaaataa aggagtttct
    16861 ggttctggat tgtaaaaaat gagttgtttt aattgataag gagtagaata tggaaattaa
    16921 tgtgagtaaa ttaagaacag atttgcctca agtcggcgtg caaccatata ggcaagtaca
    16981 cgcacactca actgggaatc cgcattcaac cgtacagaat gaagcggatt atcactggcg
    17041 gaaagaccca gaattaggtt ttttctcgca cattgttggg aacggttgca tcatgcaggt
    17101 aggacctgtt gataatggtg cctgggacgt tgggggcggt tggaatgctg agacctatgc
    17161 agcggttgaa ctgattgaaa gccattcaac taaagaagag ttcatgacag actaccgcct
    17221 ttatatcgaa ctcttacgca atctagcaga tgaagcaggt ttgccgaaaa cgcttgatac
    17281 agggagttta gctggaatta aaacgcacga gtattgcacg aataaccaac caaacaacca
    17341 ctcagaccac gttgaccctt atccatatct tgctaaatgg ggcattagcc gtgagcagtt
    17401 taagcatgat attgagaacg gcttgacgat tgaaacaggc tggcagaaga atgacactgg
    17461 ctactggtac gtacattcag acggctctta tccaaaagac aagtttgaga aggtcaacga
    17521 cacttggtac tactttgaca gttcaggcta tatgcttgca gaccgctgga ggaagcacac
    17581 agacggcaac tggtactggt tcgacaactc aggcgaaatg gccacaggct ggaagaaaat
    17641 cgctgagaag tggtactatt tcaacgaaga aggtgccatg aagacaggct gggtcaagta
    17701 caaggacact tggtactact tagacgctaa agaaggcgcc atggtatcaa atgcctttat
    17761 ccagtcagcg gacggaacag gttggtacta cctcaaacca gacggaacac tggcagacaa
    17821 gccagaattc acagtagagc cagatggctt gattacagta aaataataat ggaatgtctt
    17881 tcaaatcaga acagcgcata ttattaggtc ttgaaaaagc ttaatagtat gcgttttctt
    17941 gtggagatat ttccttcaat gtttgctact atattaaaca aaaatcagaa agcaaactag
    18001 aaagttatgc tcaaataaaa tctaaatttg acaatgtaaa ccgagtcgga tagctttaag
    18061 tactgttttg aggttgaaga tacgattttt gataggaact catcaaatag gtttaatatc
    18121 atcaatttta gatttttaag cagcatcaat aaattgcttc cttattttgt cataattttt
    18181 ttatttaaaa aattatgaca agagtgtgct attcttttta tgagaggtgt atgaatatga
    18241 taaatgtatg tgatgttgga aaagaataaa agaacttaga atatcttcaa atcttactca
    18301 agataagatt gctgagtatt tgtctttgaa tcaaagcatg attgccaaaa tggaaaaagg
    18361 tgaaaggaat atcacgaatg gatttaagta ataaagcttc aaatcttaga aaaaagttgg
    18421 gagctgatgg tgaatcgccg atagatattt ttaaattggt acaaaagata taaaatttga
    18481 cgctggtatt ttatggactc ggaaagaata ttagcggagt ctgttataaa ggaactcagt
    18541 tcagtctcat tgcaatcaat tcagacattt attaggaagg taaagatttt ctttagcaca
    18601 tgaactgtat catctttatt atgatgaggt gaagaagagt tcagtcagtc ttatcttgat
    18661 tggtgaagga gatgaaactg aaagaaaagc ggatcagttt gcttcttatt ttttaatttt
    18721 cccatcttca ctgtatagga tggttgagga aatcagagaa aatgccaata gaactcatct
    18781 tgaagtagaa gatattataa aattgggtca gttttatggt atcagtcata aagctatgtt
    18841 atatagattg aggaatgatg gataccttga tgcagaagaa attaaaaata tggatattag
    18901 tgttatagag acagcttcaa gattaggcta tgatacaagt ttatatcgtc ctttgtcaga
    18961 aagtaaaaag gaaacggtat taggataata tatcaatctg actgaacaac ttttagaaaa
    19021 gctctattcg ggtaaaattg ttattccaca agaggtgtat gatgaaatca atatacctac
    19081 aattccccat ttaaaatcta ggatagacca gttggtaact aagggttcag ctgagattgt
    19141 gagcatagac attggaactg aagaatacgc attatataga gatttaacaa gaaatcatga
    19201 tagtaacaag attattggta agggagaagc tgcttctatt tccttagcga aaaagcataa
    19261 tgggatatta ggaagtaata acctaagaga tgttaaacca tatgtagaag aattttcttt
    19321 agaacatatg acaacaggag atatactggt tgaagcgttt aaagcgtaat ttattactga
    19381 acaagagggc aatcatatct ggaataatat gcttaaaaag agaaggaaaa ttggtgcaaa
    19441 ttcattttca gactatcttc gtggaagtat tcatcaaaat agacaaaaat aaatttggat
    19501 aaatcgaact cactattcag gaggcatatg agcaattcga aaaagaaaag tgtcaaattg
    19561 agcctatagg agtagaagtg aaatagtaag tcctgcatag tggatgagaa aaaagctgtc
    19621 cttgaagttt cccctgaact atcagtcgta tgttaaacga tatgtagggt gatgtaagag
    19681 gggatagcga gtagtttttg gttattttat caaaaacctt gtattttatc atactaaatg
    19741 ataaaatgta ataaaaatga tagaataagg aaaaaccatg aatgtcaaaa agataatgtc
    19801 gatttttcaa tccttttatg ttgatgtcag tattgaggaa ctggctttga ctttaccaat
    19861 cagttttgta aaaaggtttg agtatactca aatgactttt cataaggaat catttttatt
    19921 gattaaagaa aagagaaggg ggagtttaag ttcatttgtt actcaggctc gtactatggg
    19981 tgaaaaagcc aatatgaatg ttgttttggt gttttcaaag ttatcagaca gcgaaaaaaa
    20041 gcaattactt caagctagaa tcccttttgt cgacttcaag ggaaacctct tcttccctac
    20101 attgggacta gtactgaatg cggatgatac tgaagtccct aaggaattaa cacctagcga
    20161 acaattaaca tggattgcct ttttattgac aaaagatcaa aaagtagtag atgttgagtt
    20221 gctttcacgg gtgactggac ttccaaactc aacaatttat aggtgtttga ggacttttaa
    20281 agctttagat tggttaaaca agcaaaataa gctttacaca tatacggtgt caaagaaaga
    20341 attattctta aaatccgtgt catgtttatt taatcccatc aaaaaacgga ttttattgcc
    20401 agatggcgat ataaagcaga taaaatctgt ttctaacctt ctatatggtg gtacttatgc
    20461 tttgtcgcat tcaacttttt tagctgaaac ggatgaaaat actagctatg tcatatggca
    20521 gagaaaattc aatcagttat ccttgccact ttctcagcat gctttagaag gaaaggtgtt
    20581 agagatatgg aaatattgtc cttttatatc tgagttttgg aatgatttta aaaataatca
    20641 tgataaacaa tttgtagatc cgatttctct ttatttgacc ttaaaagatg atgatgaccc
    20701 acgtatagag gaagagagtg aagtactaga aaatatgata ttacagtatc tgggagacga
    20761 tgatgccagc taatatgaaa gctatttttc aagaaatgtt tgcggatttt aaggactatt
    20821 atgttctgat tgggggaact gctacctcta tcgtattgga ttcgcaagga tttaaaagtc
    20881 gcacaacaaa agattatgat atggtcatca ttgatgaact aaaaaataag gaattttata
    20941 ataccttgaa tcatttttta gaattgggag agtatcaagg aagtcagaaa gatgagaaag
    21001 cgcagctttt tcgatttaca acaactaaac ctgagtttcc ttctatgatt gaaccattta
    21061 gtatcttacc acaatatcca ttaaagaagg atggtcgaga aattccctta cattttgacc
    21121 aagatgctag tttatcagcc ttattattgg atgaggatta ttataatata ttggtgcatg
    21181 aaaaagagat cattcagggg tattcggtat tgagtaattg tggtctatac tcttcgaaaa
    21241 tcaaattcaa accacgtcag cttcaccttg ccgtactcaa gtacagcctg cggctagctt
    21301 cctagtttgc tctttgattt tcattgagta ttaattattt ttaaggctaa agcttggctg
    21361 gatatgaggg aacgctctgc tacaggtgct caaggtttaa gtaagttcat taaaaagcat
    21421 ttgaatgaca ttacccgttt gacagcttcc ttgctaggag atgaaaagtt atcggctata
    21481 acatcaagta gtgcggtaaa agcagacata caccgttttg tgatagaatt agagcctgtg
    21541 aagtcaacta ttcctcaaaa tgatgacatt tcattggatc aaaatgaaat ttttcaaatt
    21601 ctgaaaaatt ttctcgatgg ttaaaataat tgtagcaaga tagttatatt gaattcgtct
    21661 atctctggaa actgagcaaa actcaatttc aggagaaaat gaagtcaatc ttcccacaat
    21721 caaacgtata gtatcaaggt tttcaacacc tgatattatg cgttttttga ttttcaaaac
    21781 tttttgccca gactttgttt tttatccttt agtcacttga tttgtttcag gtggttttta
    21841 tacttttcga aaatctcttc aaacaaggtc agcttccatc tgcaacctca aaatagtatt
    21901 ttgagcagcc tgcgactggc ttcctagttt gctcttgagt attagaatag gtggtttgga
    21961 gcctcctatc ggctaggaaa tggtggcaat agtcctttgc tgaggatagg gtgtgacact
    22021 caactggttg acctagttga taggaaggga attactataa aatactcagg cttccatcat
    22081 attttttgaa acgattgtgt aattaaaatg agtctgggac aatagtctct tatctccaaa
    22141 aaaagcaacg gatttgccgt tgcttgcatt cgctcaagtt cttgaagaag aattggaaaa
    22201 cctgaaccag aacattgagg agacacccgt taaagggaag gatgagcgta aaacccaacg
    22261 tcggaaactc aagaaagtct tgcgtaaagt caaggaggat ttttcaatac gtgctgaaaa
    22321 atatgagaac tatcaggaga catttgaagg gcgtaacagt ttttccaaaa ccgatccaga
    22381 tgccactttt atgcggatga aagaagacca tatgaaaaat ggtcaactca aggctgctta
    22441 taatcttcaa atcgctacgg aaaaccaatt tgttcttcac tatgatgtct tttcaaatcc
    22501 gacagacacc aagactcttc tgccattcct tgaaacctat ccgcatgact tgaagacagt
    22561 tgccgcagat gctggatagg gaagtgaaga gaacctcctt cgtttagatg aaaaggaggt
    22621 aaaccatctg attaaatatg ccatgtttga taaggaacag aagagaggct ataaacagtc
    22681 agctagaaac ttagcaaatt ggcactatga taacaaggag gatagctaca cacatcctga
    22741 tggctggtat tatcgttttc accataccaa acatcagaaa acacagacag actttcaaca
    22801 agaaatcaag atttactaca ccgacgaacc tgaatcagcc cctcaaaagg gactgtatat
    22861 gaacaaaggc tatcaaaact tgaaagttaa agaatgtcag gcgcttttat ctccccaagg
    22921 tagacagatt ttcgctcaac gcaagattga tgtggaacct gtctttgggc agataaaggc
    22981 ttctttgggt tacaagagat gtaatctgag agggaagcgt caagtgagaa ttgacatggg
    23041 attggtactt atggtcaata atctcctaaa atacaataag agaacggctc aaaattaaaa
    23101 agctagagtt ccacaattgg aaatctctag cttttttgtg gtcgagaact attttgtccc
    23161 aggctcagaa gatgttgtgc atggataaat atatcataat tgctgtctct ctatgtaaaa
    23221 agaaggctgt atcaaaaaga tttcatatgt ctgtgcatgt atataataga cttcctgcaa
    23281 aactagaatt ctagttcatg attgataata ccagcaatca aattcattcg taatccgaag
    23341 cgtttatgat gatttcgata ggttgttgaa aacattttaa acgtttttac tttggcaaag
    23401 atgttctcaa ccttgcttct ctccttagat agtgcatggt tataggcttt atcttcagct
    23461 gttagcggct tgagtttgct ggatttacgt ggagtttgtg cttgaggata tatcttcatg
    23521 agcccttgat aaccactgtc agccaagatt ttaccagctt gtccgacttt tttgataagc
    23581 tgtttttaat acagctaaca tctcttcaaa agtcgtgcgc tgaacaccaa caagacgctt
    23641 aaatcgtgca tcagttagtt gtttacttgc ttcataatgc atagaactac tataccatat
    23701 tttgtttcgc aggaagtcta ataagttata gtccagtttt tactatactt tgatattcaa
    23761 atatgttata ctatgattat caaagtaaat g
//
LOCUS       DAVFJR010000031        23458 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVFJR010000031 DAVFJR010000000
VERSION     DAVFJR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.032"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(59..1000)
                     /locus_tag="VU722_001525"
     CDS             complement(59..1000)
                     /locus_tag="VU722_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU1772463.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQVGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(990..2246)
                     /locus_tag="VU722_001526"
     CDS             complement(990..2246)
                     /locus_tag="VU722_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU1772464.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIKLHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQVSFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(2248..2910)
                     /locus_tag="VU722_001527"
     CDS             complement(2248..2910)
                     /locus_tag="VU722_001527"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU1772465.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIAIEDGQNLIAYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(2873..3529)
                     /locus_tag="VU722_001528"
     CDS             complement(2873..3529)
                     /locus_tag="VU722_001528"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU1772466.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVANPENHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(3540..4418)
                     /gene="rsgA"
                     /locus_tag="VU722_001529"
     CDS             complement(3540..4418)
                     /gene="rsgA"
                     /locus_tag="VU722_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU1772467.1"
                     /translation="MQGQIIKALAGFYYIESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNNLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIIYISKMDLLEDRSELDFYQQTYGDIGYDFVTSKEGLLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(4420..5292)
                     /gene="rsmA"
                     /locus_tag="VU722_001530"
     CDS             complement(4420..5292)
                     /gene="rsmA"
                     /locus_tag="VU722_001530"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU1772468.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGTLTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESDIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLT
                     EFASLAAALKGQGL"
     gene            complement(5423..5731)
                     /locus_tag="VU722_001531"
     CDS             complement(5423..5731)
                     /locus_tag="VU722_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772469.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLWVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(5724..6365)
                     /locus_tag="VU722_001532"
     CDS             complement(5724..6365)
                     /locus_tag="VU722_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772470.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKIIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVEALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVGLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(6367..8397)
                     /locus_tag="VU722_001533"
     CDS             complement(6367..8397)
                     /locus_tag="VU722_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1772471.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWNQFSDRYRLSFGW
                     SSVFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPDSLREQSAYYQGLFTDYL
                     QNFSSESVEVTSRKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLSGMTIYELHGKYLLAQGG
                     VLLLGLILSSVLTGDSLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(8666..9565)
                     /locus_tag="VU722_001534"
     CDS             complement(8666..9565)
                     /locus_tag="VU722_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772472.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFLFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(9637..10197)
                     /gene="rnmV"
                     /locus_tag="VU722_001535"
     CDS             complement(9637..10197)
                     /gene="rnmV"
                     /locus_tag="VU722_001535"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU1772473.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(10197..10970)
                     /locus_tag="VU722_001536"
     CDS             complement(10197..10970)
                     /locus_tag="VU722_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU1772474.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQIYATIGWHPTEAGTYTEEVEAYLLDKLKHSKIVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIAYLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(11275..12105)
                     /locus_tag="VU722_001537"
     CDS             complement(11275..12105)
                     /locus_tag="VU722_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1772475.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAETIGVQAIAMVTVPKRPVAPNAAPKT
                     TSAPQATAGTMQDVTYQSPAGKQLPNTGSVSSAALASLGLVVATSGFALLGRKTRRRK
                     "
     gene            complement(12389..12523)
                     /gene="rpmH"
                     /locus_tag="VU722_001538"
     CDS             complement(12389..12523)
                     /gene="rpmH"
                     /locus_tag="VU722_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU1772476.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(12668..13882)
                     /locus_tag="VU722_001539"
     CDS             complement(12668..13882)
                     /locus_tag="VU722_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1772477.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(14038..14331)
                     /locus_tag="VU722_001540"
     CDS             complement(14038..14331)
                     /locus_tag="VU722_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772478.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            14494..14946
                     /locus_tag="VU722_001541"
     CDS             14494..14946
                     /locus_tag="VU722_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU1772479.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVYSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(14981..16369)
                     /locus_tag="VU722_001542"
     CDS             complement(14981..16369)
                     /locus_tag="VU722_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1772480.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            16435..17397
                     /locus_tag="VU722_001543"
     CDS             16435..17397
                     /locus_tag="VU722_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU1772481.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKAHLKLLIALNAGLTGQALKDYMEG"
     gene            complement(17738..18748)
                     /gene="ccpA"
                     /locus_tag="VU722_001544"
     CDS             complement(17738..18748)
                     /gene="ccpA"
                     /locus_tag="VU722_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU1772482.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(19172..19771)
                     /locus_tag="VU722_001545"
     CDS             complement(19172..19771)
                     /locus_tag="VU722_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772483.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEIPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(19772..20869)
                     /locus_tag="VU722_001546"
     CDS             complement(19772..20869)
                     /locus_tag="VU722_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1772484.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(20869..21606)
                     /locus_tag="VU722_001547"
     CDS             complement(20869..21606)
                     /locus_tag="VU722_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772485.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKINNWQKTLRHSPINMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEMPLGSWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNKGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(21608..22492)
                     /locus_tag="VU722_001548"
     CDS             complement(21608..22492)
                     /locus_tag="VU722_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772486.1"
                     /translation="MNMIKVESLNKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQKIY
                     PNHLSNQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVMTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILVLNKGGLIRDTTPLAIRSE
                     EIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(22479..22673)
                     /locus_tag="VU722_001549"
     CDS             complement(22479..22673)
                     /locus_tag="VU722_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772487.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQAFLHQAIRGAWGLEFM
                     IFIAFPMGKEWLKGEYHEHD"
     gene            complement(22670..22876)
                     /locus_tag="VU722_001550"
     CDS             complement(22670..22876)
                     /locus_tag="VU722_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772488.1"
                     /translation="MEEEEMKNKMIVAVSLVTAGVMTYLMFSGLDEGFYHFPWELFAG
                     FGMMSWLIREGLKLVSDVKKEFEK"
BASE COUNT         6760 a         5430 c         4350 g         6918 t
ORIGIN      
        1 tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc ttaaattatc
       61 aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta ttggtcatct
      121 ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca tccagattgt
      181 caatcatatg gataatctct gcctccataa tacgtggacg gactggactt ccatattcaa
      241 gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc ttggtatcat
      301 cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg atatgtccaa
      361 gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg atgaccttag
      421 ccaagtcatg caacataatc cccgcataga gcagactctt attgagctga ggataaactt
      481 cgctaatagc gtctgccaaa cgcaccatgg tcgccgtatg ataggccaag cccgtttcaa
      541 aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca tacttggtgt
      601 agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc atttgcgaca
      661 tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg gctgggtcat
      721 tgggttcacc aacttgaggc aggcggagag taatttgatt gacttgaggg gtattgttat
      781 aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc tcaatgttat
      841 gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg aaggtaaagg
      901 ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt aggtaaaagc
      961 cttcaaataa ctcatctttt ttcatgtgac taatcttcat attcttcctc attttcttga
     1021 aaatggagta gatcaagcgc aggctcacct tctgacaact caatgtgacg gagcgtccgc
     1081 tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc atgttggaga
     1141 tgtttttgcg ccttgaccag aataccacca aacttgccaa actcggtctt gacactggca
     1201 agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa accaactgat
     1261 agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg ttcttcccgt
     1321 ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc ttctgtcgga
     1381 acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt cctaatatcc
     1441 ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat ttcatccttg
     1501 tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa cttagagtca
     1561 attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc atactccact
     1621 cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg tgtcatgatg
     1681 tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt ggttccagag
     1741 agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc aaggccacga
     1801 ttgacagact ccagttgttt agaaactgtc tcaaaggaaa cctgtaagcg tgtctgcaag
     1861 gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg ctcatttgat
     1921 tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag attatctgtc
     1981 atttcttgac ggacttgggt cagaccttga tgcaatttaa tccgcacttc ttgcaaacgg
     2041 tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct ggcttggtca
     2101 aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct cttacttaag
     2161 tgtttctcct gcctatcctg cctttgccaa atcagaaaga gaccagctag gttggcaatt
     2221 aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca gtacgaccac
     2281 ataaccatct gggcaagtta ccgacacttc cctatctata tattcgttag aagcgtacac
     2341 ttttttaaag aaaaaatttt cctctgtcaa ctcatacttg gctccaagaa tagtcagctg
     2401 gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt ctagctgact
     2461 ggtcccttct ggacaatagg caatcaagtt ttgcccatcc tcaatcgcta tctggcgcat
     2521 atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat ggtcaatacg
     2581 gccacccaag gcaccgaaaa tagtgacctg agcctgagga ttttgttcaa agatggttaa
     2641 gagagccaat tccagatctg tatcatcctt ttctggtcgt gcttggacaa aatactgggc
     2701 acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatctc cgactgctag
     2761 agcaagaggt aagtcttctt ccaataccca gagcgagcct cgatccaccc caacaaaagc
     2821 atcaaaatct gtccgataat gaccgcggtt tccgcctgca aaaactgcaa ccctagtcca
     2881 gttgttttct gagagtttgt actcgctcat tgacttctcc cttaaagaca taggaacctg
     2941 ctacaaaaac agtcgcacca gcttctttgg cttgagcaat agtttggtca tcaatcccac
     3001 catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc aactcacgaa
     3061 ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta accgtcatga
     3121 ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactggt gtgccaggat
     3181 tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg ccatgaatat
     3241 gaggtgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca aagtcttcca
     3301 gatgattctc tggattagct accatcaagt ggcagtcaaa gaccatcttg ctatgaggtc
     3361 gaagactctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga ctgtccatga
     3421 tatcgatatg ggcatattct gccccagttg cttctaggcg tttgatttca cgttcaaagt
     3481 tggcataatc tgctgctaga attgacggag caatcttgta ttgagacata ggtttctcct
     3541 tattttggaa tttttttgct gactttttta taggtttctc tgcgattttc aatttcgctg
     3601 aggaattgca ggtagttgtc aaaacggaag ggcgcaatgg taccttcttc aactgctggc
     3661 ttgacagcac aggacggctc atgggtatgg gtacaagtac ggaacttaca gtctcgactg
     3721 acagtagcaa tctctggaaa ggcctgattg aggtcttcag ccgttgacac ttcataatcc
     3781 agtgatgaaa agcctggtgt gtctgcgatt ttacccccat tgaggttgta aaaactaact
     3841 gctcgagtgg tatggcgccc gcgacccaga ctgtctgaga tttctcccgt ttcaagatta
     3901 aggtctggtg cgattttatt gagaagggtt gattttccaa cacctgtctg ccccataaag
     3961 actgtaacct tgcctgttaa caaaggaagg agtccctctt tactggtcac aaagtcatag
     4021 ccaatgtcac cataggtctg ctggtaaaaa tccaattctg accgatcttc cagcaaatcc
     4081 attttagaaa tataaatgat aggatggatg cccttatgct ccaaaagaac caagaaacga
     4141 tccagcaaat tgctgttaaa atcaggttcc ttgacagaca tgatcaccac agcttggtca
     4201 atattgacaa taggcggacg gaccagattg tttttccgtt catgaatctt gaggatatag
     4261 ccttctgaat tttcctcggc agagaaatct acccagtccc caacgtaagg agtatggcct
     4321 tttttacgga aattcccacg cgcgcgtgtt tgatagacct ggccatcact ctctatatag
     4381 tagaagcctg ccaaggcctt aataatttgt ccctgcatct tagagccctt gccctttaag
     4441 cgcggctgct agactggcaa attctgtcaa gctgagtgct tctccacgca cacttggtga
     4501 caagcctgct tggtccaagg ccttagtcag cttgtccttg acttcttcag tcttgccaaa
     4561 gtaacctgtc aggttattcc ataaggtctt gcggcgatga gtgaaactag ccttggaaac
     4621 cttaaagaag aagttctcgt cttccactgc tacagctggc tctggacgac gcaccatttt
     4681 caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca cgataaaggc
     4741 aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag ccttggtgtt
     4801 aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa actcacaaaa
     4861 aggaatgtca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt aaggcaaatt
     4921 agccactacc ttgattggca ggtcaggatt tttaaaattc tggatatgtt gcgccaaatc
     4981 aaccttgaga atatcttcgt taactacggt cacattatca aaatcacgca gggtatctgc
     5041 caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg cacgctcagc
     5101 caaaaattct gtcaaggtac caatacctgg cccgatttcg atgacattga cctgatcatc
     5161 aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcaaaa aattttgccc
     5221 aaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca cgctataatc
     5281 tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac acattcccct
     5341 tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag aaagatagtc
     5401 ttggaaatct ttaaaagtgg ccttagcagt tctctcgaaa catgcgttca aaaaaatcag
     5461 cttcttgata acttcgattt tcgggtaggg tcaaatccac atcctcctcc acatcatcca
     5521 ctgtcagttc aaccgtctga ggtaaatttt tcaaacgata atgcttttgc ctttgccctt
     5581 caatactagc aaaatcaagc aaatagccat gcactcggat ttgaacccaa aggagatgat
     5641 tggtcatatt ttccatgatg aggatatctt ctaaaccacc tctggcacta ggataatcag
     5701 ataccctgcg aatacggatt ttttcacaca tgagcaagtt tcctcatatc aatgatttca
     5761 tcagccttat tccagactag gggattatgg gtcgcaatga tgatcattcg attttcatct
     5821 ttcaagccca ccaagagatt cataacctcc tctgaatttt caggatcaag agctgctgtt
     5881 ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag tcttagcaag ggcaactcgt
     5941 tgggcctctc ccccagataa agtataaatt ttttgttcta gatccaaata ccctagatta
     6001 actttttcta aagcctccac ttgcctttcc aaacgttcta cttttgaaat cttttgacca
     6061 acaaagccca aatccaaatt ttctttgatt gattggtttt ctaaaaggcc aaaattttga
     6121 aagagatagc ccatctgatc tcgaaaatac tcacgagtgg gaatgatttt taaatctttc
     6181 ccctgataga gaacccttcc tccatctatc ttctctagct ttcccaagat attcagcagc
     6241 gtcgtctttc cgcttccact cttcccgatt aaggcataga ccttgccctt ctccagtttg
     6301 agattcaaac cagagaaaat cgctcggtca ttaaatttct tttccaatcc ttgaatatca
     6361 atcatcttat tttcctttca atactgccat gctaccagct tcttcctttt tatcctgcct
     6421 tactaaaatc aagagggcgt taagagtaaa taaagctaca actaaagcgc tgatcaagct
     6481 atctcctgtc aaaacactag atagaattag gccaagcaag agaactcctc cttgcgccag
     6541 taagtacttg ccatgaagct cataaattgt cataccagaa agacgtttaa tcataagctc
     6601 ccgtctaaac tgctcaaaat agagaagatt catggaatca aataacaaga tagccgtaga
     6661 cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc acccgtttgt catttagtac
     6721 cttggcaaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca gaccttgctc
     6781 ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat tagccgtagt
     6841 tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta gaactacaat
     6901 aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga ggaaacgttc
     6961 ctgtcctgtt tctgtaaaag ctagccttac ctgtgggaag tagtgtttcc gactcgtcac
     7021 ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt ggtagtaggc
     7081 agactgctct cgcaagctat caggcaagat cagcccaaac tctccctcag acaagttttg
     7141 catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat agcgtggtga
     7201 gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat ctaggtccac
     7261 ttctgctcca tctgagaaat tgtcaacatt gctcataata taaaaagagt ctgtattggc
     7321 taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc cttcttcatc
     7381 ggcaaataca ctagaccaac caaaggatag acggtaacgg tctgagaact ggttccattt
     7441 attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag ctgtcgcact
     7501 cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca tcatacgttt
     7561 gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac caagtagata
     7621 gacgacactt agtaaggtag aaatccctgc caaggtcaat ccataaagta gaagagcaat
     7681 gatgaccagt tgcaccgttg ccataaacaa ggcaccttga taccagagaa tccccaatcc
     7741 caaaagactg gataccagca ctgagcagat aagctgtctc acatcttcta acactggtct
     7801 gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct gacgaaggga
     7861 tttgatccga taaataaggg tcagactcat aaaggtcagc agaaaaatag ctaaactcag
     7921 tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt ctccattcga
     7981 aacaaagcct tgataaccaa gctctttcaa ggtggtctgt aagctcactc catccaaact
     8041 tcctgataca atcaagtaag accctaataa atcactcgtt tctgcactct ccttggagga
     8101 aatggtcaga ccttctggaa gctttccctc accataagtg gcataggtaa agcgtgtttc
     8161 tccagcttca tttggctcaa caatccgacg ggcgatgaga ctattatgct ctaccgccaa
     8221 gtgactcaaa gcctctgtca cctcttcgcg actagctact ggttgattta tcatcattcc
     8281 tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt caacggaagt
     8341 tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac gtttcatcat
     8401 ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac tgccatgtta
     8461 agaagtttat taagtttttt ctactagcaa catcttcaaa tatattatat ccgttttttc
     8521 aagaactatc aagggcatca atgtccttaa aatctaacca tttcgtgtca tttttagctt
     8581 atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg agaacaagga
     8641 catttttgtc actgattcac tatgtttata aatatttttt gacatcctct tgccattcct
     8701 ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt ttagaagact
     8761 gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc ttccacaaaa
     8821 acagaaatac aagaggtttc ttttgataat cttgagtttt atccataatt tcttgtaaac
     8881 acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa cacattcctg
     8941 aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt ttctgttcca
     9001 aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct tttctaatga
     9061 gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa acttcttttt
     9121 ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc cttctagttc
     9181 tagaagtatc caaacacgcc tgcaatactt cacacgctaa ttgttcttct ttaggaagat
     9241 tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg tactcctctt
     9301 ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa gcagaaggaa
     9361 gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga gcaatatagt
     9421 ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt tgacgaactg
     9481 tcagttcttg ctcatctcca caaaaatctg gacgactaac tcctttttct atccgaatct
     9541 ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt cgaaaaatac
     9601 tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt tcatagcttc
     9661 ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt gcttgccgtt
     9721 agaatagccg attcggagag tctctccgag atattctcta cgcttacggc tgtctgcccc
     9781 tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac tctcatgttc
     9841 aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg catgctcaat
     9901 tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct tgagaaaggc
     9961 atgctgaact gttggaatgg ccgtcataat catgcgccga atccgctccc cattaaaatc
    10021 tgggtctgta aagacaatga ctccatgacg ttggtgtaga cgctgaattc gctctatatc
    10081 ctgatcattg atggcagaac ctcgtgtctc ataggtctcc acatcgaaat aacgcttgag
    10141 attgaccgta tcatcgcgac cttcaaccac gataacttga gaaattttct ctttcattac
    10201 ttgctgtcca atccaaaaat tcgttctgca tttgcagtcg ttgctaccgc cagctcttct
    10261 gtcgtcatac cacgcaagta agcgataaag tcgaccacat agcgagtata ggctgtttta
    10321 ttttcacgac cacgcttggg tacaggtgct aagtaaggcg catctgtttc caccaacatc
    10381 ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt gaaagtcacc
    10441 actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca ctcaagcgtc
    10501 cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt gataatctca
    10561 taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa gtccttagat
    10621 agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt catccaatgg
    10681 tagtctaagc caatttcacc taaagccaca atcttggaat gttttaactt atccaacaag
    10741 taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc aatagtcgca
    10801 tagatctgct catactcatc taccaactcc aaggcatgct caatcgtcgg tttatcaaaa
    10861 ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc ttctgcctca
    10921 cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat ctcttctaac
    10981 ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt ttcggtttcc
    11041 cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt gcccatctcc
    11101 tattccacag ttagagacag aagagattgg ctacattgat agaatattcc tattcagcta
    11161 aagtatatga ttatcttggg ttctcacttt tctcacccat cactaggatt gatgacttct
    11221 caaaatcccc cttataattt aactttaagt agagaataga attttctagc tgttctattt
    11281 tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca ctagaccaag
    11341 actagcaagt gctgcacttg atactgaacc tgtgttaggt aattgtttgc cagcaggtga
    11401 ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg ttgtcttagg
    11461 agcagcatta ggagccactg gtctcttagg aactgtaacc atggcaatgg cttgcactcc
    11521 aatcgtttct gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc
    11581 gcctttgatt tcatcctgct tgttcttggc tgctttttca atggcatttt tagctgattc
    11641 tttttcagta gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg
    11701 agctgatcca cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccagt
    11761 attgcctccc ttatctccac ctggtgtagt ttctagctta tactctggtg tagcttcttg
    11821 agttacagat tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac
    11881 tgaaccatct gggaatgtga ttgttgctgt accatctcca gctacattga ttgtagctcc
    11941 gtctaatgct gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa
    12001 atgagttata tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc
    12061 agtcggttta gtactatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat
    12121 tgtaatagct gaaccatctt taaagacgat tgtcgctgtg ccatctccag ctacttcaac
    12181 tttatagtaa aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta
    12241 acaatgtttt agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc
    12301 gaatccattt gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc
    12361 tactgatttt tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac
    12421 gacgagctgc caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt
    12481 tgcgcgcacg acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat
    12541 agattttgta ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt
    12601 ctatctgatt ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat
    12661 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
    12721 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
    12781 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
    12841 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
    12901 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
    12961 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
    13021 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
    13081 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
    13141 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
    13201 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
    13261 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
    13321 ccttaggata aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat
    13381 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac
    13441 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
    13501 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
    13561 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
    13621 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
    13681 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
    13741 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
    13801 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
    13861 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
    13921 actagaaaga gaatgcgaca agtttactga aatatgttac tagtttcgta tagaagaaaa
    13981 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
    14041 cataccaaaa gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa
    14101 catgaggaaa agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag
    14161 aaataagatt agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag
    14221 aagcggtacc agactctcta attgacagat catgatcact tctaccaaga ctgaaactag
    14281 gataattcca taataaagga aatttgattt ttgaaaagag tttttcatca ttctcccttc
    14341 cttcacttct ttcctgctat cctttctttt tattttatca tatatttata tagagtttaa
    14401 gccctaatat tcttttgaaa aatacttttt ttgctttact tctatagtga aaaggtttac
    14461 aattatagta agaaaatttc aggaggtttc attatggcac aacgttacca aaatatcatg
    14521 gtcgcaatcg atggttctaa ggaagcggac ttggcttttg tcaagggagt ttattctgct
    14581 ctacgaaacg acgctaaact caccatcgca catgtcattg acacacgcgc tctccaaagc
    14641 gtatccacct ttgatgctga agtttacgaa gaactccaag tcgacgctga aagtctgatg
    14701 aaagagtacg aaaaacgtgc taaagatgct ggggtagcag atgttcatat cgtcattgaa
    14761 atgggaaatc caaagaccct gctagcacgt actattccag atgccgagga agtggacctc
    14821 atcctcgttg gcgcaactgg tctcaacgcc tttgaacgcc tcttggtcgg ctcttcatct
    14881 gaatacatac tccgccatgc taaggtcgat ttgctggttg tgagagaaca agaaaaaacc
    14941 ttataatcac aaagaaaagg agcccctagc tcctttttgt ttacgattta tttctctctt
    15001 tatggcgttc gtaagccttg agctggcgct gcagttcctt tttaatagca ggttctggag
    15061 catatttttc ttcccaatta tctggtttta agattttatg ggtcactgga tcaaaatgag
    15121 ccttgccatc tggaaaaatt ttccccatat tagcctgatg gacaatatca aaaatacgtt
    15181 ctgggtcgac ccccatcaag acaaaactgc cgtaggtgaa gtaaagcgtg tcaatcaagg
    15241 catccacttg ccctatcaaa tcttgctgag caggtgtctt cttggctact ttacctgctg
    15301 ccttatcaag ggcctgatga agttgcgata cagcttgacc aaaatcttct tcagaaggac
    15361 tggctgctcg aacaaactcc accaattctt ctattttaaa accagcccta tgggttgcac
    15421 cctctaaatc ccaagctcga ggttcttctt gggttcgttc atccatcatg tggtggaagg
    15481 tcttgacctt attgaaatga tagtcacggc tgacaaagac tttttctgaa gacaaaacac
    15541 caaaatgttc caaggccttg tggatcccat cttgttgatt gctagtggta atgtgcttgg
    15601 cagcttcctt gacactgcta ctaccatttc ccatagcgac cgacataccg acgccagcca
    15661 gcatttcaag gtcattatct gagtcaccaa aagccatgac ttggttgagg tcaaagccat
    15721 attctttccc aactcggcga atgccttcta atttagaatt tccctgattg atgacatccg
    15781 atgcaaaagg attgctacgt gtcaatttca agtcttcaaa atcagctgcc gccttctcag
    15841 attcttctgg tgtcatcagc atcaaaactt ggtagatagg ctgattcatc aggtgaagca
    15901 ggtcctcttc cttttgggga acaaccttgc tgaccatgcg attaaaagac tgactcaccg
    15961 tccgagttaa aacagaggga acgaagcgac taattcgttg ggaaaaagaa cccagaccaa
    16021 aggacatgat tttagaaccc aacatggcat ccttggtccc tagggcaatc tccgtgccct
    16081 cttttttagc atagctaatt agatggcgca aatgtaactt ggaaataggg ctcgtgaaca
    16141 agactctgtc tttactaaag atatactggc cattataggt taccgcaaaa tccagatcca
    16201 aatcgtccat caattcctta acaaaaaaag gtcctcgccc tgtcgctacg ccaactagta
    16261 ccccttgttc tttgacaatc ttaatcgcgt ccttagtgga tttcaaaaca ctcttgcgat
    16321 tgttgaccaa ggttccatcg atatcaaaaa aaacagcttt gacttccatc ctattccaat
    16381 ctcccctttt gtgatacaat gattatacca catttcagaa agagtgagta aatcatgcct
    16441 aagaaaatcc ttgttttaca tacgggtgga actatttcca tgcaggccga tgcttctggc
    16501 gctgttgtga cgagttcaga taatcccatg aaccatgtgt ccaacccact tgaaggaatc
    16561 caagtccacg ccttggactt ttttaacctt ccaagtcccc atatcaaacc caaacatatg
    16621 ctggtcctct accagaaaat taaagaggaa gcagataact acgatggagt ggtgatcaca
    16681 cacggaaccg atactttaga ggaaacagcc tatttccttg ataccatgga agttccccat
    16741 atgcctatcg ttctaacagg agccatgcgt agctccaatg agctcggtag tgatggtgtt
    16801 tataattacc taagtgcttt acgagtggcc agcgatgaca gggctgctga caaaggagtt
    16861 ttggtcgtta tgaacgatga aatccacgct gccaagtatg tcaccaaaac acatacgact
    16921 aatgtcagca ccttccagac tccaacacat ggccccctcg gtctcatcat gaaacaggaa
    16981 atcctctact tcaaaacagc tgaacctcgt gttcgctttg accttgatca catacaaggt
    17041 ttagtcccta tcatctcggc ttatgctggt atgacagatg agctgattga tatgctggat
    17101 ttagaacact tggacggttt gattatccaa gccttcggag ctggtaatat tcccaaagaa
    17161 acggctcaaa aattagaaag ccttctgcaa aaaggaatcc cagtcgctct ggtatcacga
    17221 tgctttaacg gtattgccga gcctgtttat gcctaccagg gtgggggcgt acagttgcaa
    17281 aaagcaggcg ttttctttgt taaagaactc aatgcccaaa aagcccactt gaaactcctc
    17341 atcgccctca atgccggact aacaggacag gctttgaaag actatatgga aggctaatac
    17401 tcttcgaaaa tctctgcaaa ccacgtcacg tcgccttacc gtatgtatgg ttactgactt
    17461 cgtcagttct atctacaacc tcaaaaacat gttttgagct gacttcgtca gtttcatcta
    17521 caacctcaaa aacatgtttt gagctgactt cgtcagttct atctgcaacc tcaaagcagt
    17581 gcttttagct gacttcgtca gttctatcta caacctcaaa acagtgtgtt gcgcagcctt
    17641 taaccagccg cctagtccgc tctatggtat tcattaagtc aacatctctt gtttaagagc
    17701 acaaaatcag gaaatcttct cgattccctg attttttcta tttacgtttt cgtgttgagc
    17761 tacgttctgt caaaccatga ggtaagagaa cttcacgttc ttccaactct tccttatgca
    17821 taatcttggt caacatacgc atactaatgg caccaaggtc ataaagaggt tgggcaatcg
    17881 ttgtcaagtt tggacgggta aagcgtgaga tttgtgaatc atcactagta ataatttcaa
    17941 aatcttctgg cacagaaaca cccttatcag ccaaaccgtt caagactcct gctgccaact
    18001 catcacctgt cacaactgct gcagttgcat ttgatgaaat caaacgctct gctaaggcgt
    18061 aaccatcatc atagctatat ttagattcaa ataccaaacc ctcactataa gtgattcctg
    18121 cttttttcaa ggtttccttg tagccaacta aacgaacctt accattgatg tcatccacta
    18181 gcggaccgct aacgaaagca atacgctcat tttctttaac aaggtaactc actgcatcaa
    18241 ttgttgcttg cttatagtca atattgacac ttggcaactg gtgctccaca tcgacagttc
    18301 ctgcgagaac aatcggagta cgtgaacgcg aaaattctga gcgaatttta tctgtcaagt
    18361 gataacccat atagataatg ccatctacct gctttgaaaa gagggtattg acaacagaaa
    18421 cttctttctc gttatcttca tcgctattag ctaggacaat attgtacttg tacatttctg
    18481 caatatcatc aatcccctta gccaaactcg aaaaataacc attggtaata tttggaatca
    18541 cgacaccgac agtggttgtc tttttacttg caagaccacg cgcaactgca tttggacgat
    18601 aatccaaacg atcaattacc tctagcactt ttttacgggt attctctttt acatttttat
    18661 tgccattgac cacacggctg accgtcgcca tggaaacacc tgcttcacga gcgacatcat
    18721 aaatggttac tgtatcatct gcattcattc cttttcctgt cctttctatc tcacacattc
    18781 ttttacaagt agaggtgctg attgaagctc tatatctact tacaaaagtg aagatgtgaa
    18841 aatttcgttt tcatatttct acttattcca ttctatcact aattgtaaac actttcaagt
    18901 gttttttgaa gattgattga aaaaatttca tagaaaacct aggtttagct ccttgctacc
    18961 accttagact aaacaaaaag gaggaaacta agccctccta aagttatagt aaaatgaaat
    19021 aagaacagga taaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
    19081 aggtgtacta ttctagtttc aatctactat aggtattgtt ccattcacta ccgtcaattt
    19141 tagcacatag tcttcataaa atattatatc atcataacca accagattct tttgcgatat
    19201 tagctgcctc tgttcgatta ccagcatcca gttttgaaag aatattggtg acatagtttc
    19261 gaatagttcc gtttgagagg taaagctgat ctgcgatttc ttggttggat aagccccggg
    19321 cgattccctt taagacagca atctcttgtt ctgtcaacgg attgggacgg gtcatcacca
    19381 cttccatcaa ttcaggcgaa tactccttgc gtccttcgag gacggtgtgc aaggtttgca
    19441 tgaggtctgc aatgcttcgt tcctttaata cataagcatc tactccagcc ttgaccgcac
    19501 gttcaaaata ccctgggcgc ttgaaggtcg tcactacaac cacctttgtt tcgagctttt
    19561 ctgctcgtat ccactccaag acttcgagtc ctgtcttaac aggaatttct acgtcaagga
    19621 tggcgatatc tacagactcc ttttctaata gttgaattgc ttcttgacca ttcttggctt
    19681 gtaagacaga ctctacatct gcttgaaagg caagcaactg gcacatggca tctcgcaaca
    19741 tactttgatc ttctgcgact aatactttca tctactttct ctccttataa ggtagtcgaa
    19801 cttgcacttc cgttggatgt ttctgactga ttacacttac ttctcctgaa aatggagaaa
    19861 cacgatctcg gactgtatgg agctcatctc cttttagaaa agcaaagccg cagccatcat
    19921 cacttactgt taaaatgagt tctttctctg cccgttctaa tttcaggtag gccttcgacg
    19981 ctttggcatg tttgataata ttggtcacca actcaagcaa aatcatggaa gccgttgact
    20041 ccaattcttg agtaagacta gcagtatcta gttggttatc cgtttccacc tcaattccag
    20101 caatttctaa catctttttc acagtctcta gttcggatgt caaagttcta gacttaagat
    20161 tttccacaat ggttcgcact tcattcatgg aatccttact gatctggtga atttctttta
    20221 attccttttc cacctgtgga taagcctcca tctgaaataa ctgcaaggct aaatctgtct
    20281 tgacactcaa catagcaaag gtatgtccca agctatcatg caaatcctga ccgatacgac
    20341 tgcgttcatt ttcagcaagc aatagattta tctgggcatt ttgcttagcc tgagcttctt
    20401 tcaaatcctc cacaatacga atccgaacca agccaaaagt cattaaatcg acaaaagcaa
    20461 gaattacaag tagatagaat agaaactcaa cttcgattct ctgaaaaatc aacagttggc
    20521 ccacaacaag gacttgagca agaagaaaag tccagacatg taaagacttt aaaccaccta
    20581 cgctgaaatg ataacttaag agattggata ggaaaaagaa aaaccagata taattaacag
    20641 caacaaaggc agtattccca actacataag tcagcatgag gccccaatat agccaagata
    20701 ggcgctggct cttagttgtt aaaacaccca aatacgccac tacaaataga atatcaatca
    20761 ataaatgcca ggcagaaagc cacccagtca ctacaggtag gatgggaaaa agcataaaaa
    20821 tcaaactggc ccaaaacata tagtgtatgc ttttcagtct ttcaagcatt aagcattctc
    20881 cttatgacct tgaaggtaaa tagtcaaacc aaataaaact gctgaaaaaa caagtagata
    20941 aactgtggct gatagattga tgccaccctt gtttaagaag gtcttgagta actccatcaa
    21001 ctgataggtc gggagacact taccgactgc ttgcatccag tctggaaata aagagatagg
    21061 catccagagc ccacctaaaa cagccaagcc aaggtaaaga agattgccca cgacagacat
    21121 cagctgacta gttggtaaga gcgtcaaggt caagccaagc gctacaaaag caatacttcc
    21181 caaaataagc aaaatcgcag ccccaaccca gcttcctaga ggcatctcta cacctcttac
    21241 aaaatgccca actgagaaaa ccaccaagat tgaaaccaaa taatcaacca gcatacttgt
    21301 tatctttgat agataatatt ctaccatatt tataggacta tgacgtaatg ttttctgcca
    21361 gttgttgatt ttatctgtat gtaaaacagc tgggaatgaa aagatagctg tcgacatcat
    21421 ggaaaaagcc gtcatggaga tgaggtaatc acgcataaaa ttagctggtc caccaggtgt
    21481 gtcctggtac atgcctgaaa agaataaata gaaggctgtc ggcatcccta cggataatag
    21541 ataatagact aattgtcgtt tggtcaatag aaattctatc ttgtttagtg cgatccatcg
    21601 tttcatctta gtcatctccc ttttgtgttt cttcaaagat tgtatccaac aagctacgat
    21661 tattgacttc aatttcttga atcctacatc ctgcttgcac taacagttgc caaaaagcat
    21721 ccgcttcacg tgtaactact tgcaaagcat cttgtttttg tgaccagttt tcaaccaagt
    21781 tagactgctc aatgacttcc ttgtaagcta gaggaaggat aaagtgcttt tcaatctcct
    21841 cactgcgtat ggctagaggt gttgtatcgc gaatcaaccc tcccttattc aagaccaaga
    21901 ttcggtccgc tgtatgctct acctcttcga tgtaatggga cgaatagaga atggtaactc
    21961 cctgcgcttt tagatcctga acaatctccc aaaaacgttg gcgggttgag gtatccatgg
    22021 ccgcagttgg ctcatctaaa aagacaagtt ttggtcggcc aatcaaggtc atgacaaaag
    22081 agaaaagacg cttttgccca cctgacaatt tttctgcaaa ttgctctttt tgttgctggt
    22141 caaactgcaa tagttgatcg atttcctgat tactcaagtg atttggataa attttttgaa
    22201 agaaagcaat caactctttt acctttagtt tctgaacgat tacattctct tgagggagat
    22261 aggatctagt gtagtctaac ttagagctcg tcactggcaa gccttggatg gatacttgac
    22321 cgcttgtgac cagtttatct ccaagcagac agtccaagag tgtggtcttc ccagcaccat
    22381 tgggcccaat caaggcgacg cattcacctt cagctacctc aaaggaaata tccttcaaaa
    22441 tagccttgcc cttgatgttt ttatttaggc tttctacctt aatcatgttc atgatattct
    22501 cctttcagcc actcctttcc cataggaaag gcgataaaaa tcataaattc tagtccccag
    22561 gcaccgcgaa tggcttggtg aaggaaggct tgatcaaacc aacctgtaaa catttctacc
    22621 aaccatacta ctagtgatag tccaataaaa agatagagaa acgctttttt catttttcaa
    22681 actccttttt cacatctgag actaatttca aaccttctcg gataagccag gacatcattc
    22741 caaatcctgc aaatagctcc caaggaaaat gataaaatcc ttcatccaat cctgaaaaca
    22801 tgagataagt catgactcct gcggttacta gactcactgc gacaatcatt ttatttttca
    22861 tctcttcttc ctccatttca tacttcaatt atagactttt gaagtttgcg gagctagatg
    22921 cttctgtcac taggaaatat gacaactgtc ataaaagatt ctgttcaaaa caagcaagat
    22981 acactataca ataaaacaca atcagaaaaa tctaaggcaa cttcctcaaa agagatatca
    23041 aacccaattc acaccataat gtaaactaat acttatttaa aatcaaaaag agtagaaatt
    23101 tttatcagac aaacacatat atagtgtatt gaatctataa cagtaggcct taaatactaa
    23161 aatatttcta taaattaatt taactttcct gatagagctg ttcatatctt atttcaattc
    23221 tctaaattat acgttgaaca aaacccttct atttctttct taaaaattta taagagttat
    23281 aaaatctgtt aaatttcaat gtgtatacct aaactacggt atttattgaa aaaactggag
    23341 acaaaaagta tacgttgcca aaatgaatta ctgaaaatca aaaaagagag aaccaaactg
    23401 attccctctt aatgtatata atatctagtt ttaaaaatac acactcacat atctctgt
//
LOCUS       DAVFJR010000032        22925 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVFJR010000032 DAVFJR010000000
VERSION     DAVFJR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.033"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..94
                     /locus_tag="VU722_001551"
     CDS             <1..94
                     /locus_tag="VU722_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEU1772489.1"
                     /translation="GVKYGKILGPWGAAIGGAVVCGYLAYTATS"
     gene            338..487
                     /gene="blpO"
                     /locus_tag="VU722_001552"
     CDS             338..487
                     /gene="blpO"
                     /locus_tag="VU722_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU1772490.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CVTTV"
     gene            591..710
                     /locus_tag="VU722_001553"
     CDS             591..710
                     /locus_tag="VU722_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU1772491.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSPKKDTDSTP"
     gene            1008..1172
                     /locus_tag="VU722_001554"
     CDS             1008..1172
                     /locus_tag="VU722_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772492.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1169..1573
                     /locus_tag="VU722_001555"
     CDS             1169..1573
                     /locus_tag="VU722_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU1772493.1"
                     /translation="MKIFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSLVFQF
                     FLVVINLASILVTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAILCLTIMLLLIWGLKYYKK"
     gene            1734..2159
                     /locus_tag="VU722_001556"
     CDS             1734..2159
                     /locus_tag="VU722_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU1772494.1"
                     /translation="MKKQKIKSLLLVPLVFASITAGLAYAEEQPTTSSTQANDSSLVA
                     PDLPSAKEKVEHKPSVVTPEEYEKNVTDFKKIDIEAVRQSFTGDQLEHTIYFGRKTCS
                     HCRQFSPELKEFNNLIEKKLEYYDLDGKDFDGEAREFLF"
     gene            2302..2760
                     /locus_tag="VU722_001557"
     CDS             2302..2760
                     /locus_tag="VU722_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772495.1"
                     /translation="MKSSEETVTESVRDENTRSDSMNISDKVVSDSKGMSDKKRTEMK
                     ISNANSENSGKVESTNSTSEAKTTQSGNLAMLDNKNQLETLKPIFDAAQENKTSLTDV
                     KDADYVSESITSNEKLLLKTGEEESYQLIRLAVAFFMASIMIKVKQKIHK"
     gene            3006..3239
                     /locus_tag="VU722_001558"
     CDS             3006..3239
                     /locus_tag="VU722_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEU1772496.1"
                     /translation="MDTKMMSQFAVMDNEMLARIEGGDVSDIYRGYANQVSPFGSYPP
                     ILKNSGPFPVSGYCPRGYHDRGYIGAGFHLCGI"
     gene            3271..3960
                     /locus_tag="VU722_001559"
     CDS             3271..3960
                     /locus_tag="VU722_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772497.1"
                     /translation="MKKYQLVFKISAVLSYLFFVFGLSQLTLIVQNHWQFSSQVGNFF
                     WIRNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVVVLHISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            4003..4251
                     /locus_tag="VU722_001560"
     CDS             4003..4251
                     /locus_tag="VU722_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772498.1"
                     /translation="MYKHLFFLDSKTLDRLTPYIIVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLDLKNDV"
     gene            4281..4892
                     /locus_tag="VU722_001561"
     CDS             4281..4892
                     /locus_tag="VU722_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772499.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            5054..5848
                     /locus_tag="VU722_001562"
     CDS             5054..5848
                     /locus_tag="VU722_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU1772500.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5845..6480
                     /gene="trmB"
                     /locus_tag="VU722_001563"
     CDS             5845..6480
                     /gene="trmB"
                     /locus_tag="VU722_001563"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU1772501.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6606..7085
                     /gene="rimP"
                     /locus_tag="VU722_001564"
     CDS             6606..7085
                     /gene="rimP"
                     /locus_tag="VU722_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU1772502.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7129..8265
                     /gene="nusA"
                     /locus_tag="VU722_001565"
     CDS             7129..8265
                     /gene="nusA"
                     /locus_tag="VU722_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU1772503.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8287..8580
                     /locus_tag="VU722_001566"
     CDS             8287..8580
                     /locus_tag="VU722_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU1772504.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8573..8872
                     /locus_tag="VU722_001567"
     CDS             8573..8872
                     /locus_tag="VU722_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU1772505.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8889..11681
                     /gene="infB"
                     /locus_tag="VU722_001568"
     CDS             8889..11681
                     /gene="infB"
                     /locus_tag="VU722_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU1772506.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKSAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11932..12282
                     /gene="rbfA"
                     /locus_tag="VU722_001569"
     CDS             11932..12282
                     /gene="rbfA"
                     /locus_tag="VU722_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU1772507.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12561..13344
                     /locus_tag="VU722_001570"
                     /pseudo
     CDS             12561..13344
                     /locus_tag="VU722_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13346..13528
                     /locus_tag="VU722_001571"
     CDS             13346..13528
                     /locus_tag="VU722_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772508.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            13943..14176
                     /locus_tag="VU722_001572"
     CDS             13943..14176
                     /locus_tag="VU722_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU1772509.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            14176..15510
                     /locus_tag="VU722_001573"
     CDS             14176..15510
                     /locus_tag="VU722_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU1772510.1"
                     /translation="MTDERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15520..15774
                     /locus_tag="VU722_001574"
     CDS             15520..15774
                     /locus_tag="VU722_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU1772511.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15870..16265
                     /locus_tag="VU722_001575"
     CDS             15870..16265
                     /locus_tag="VU722_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU1772512.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            16678..17127
                     /locus_tag="VU722_001576"
     CDS             16678..17127
                     /locus_tag="VU722_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU1772513.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            17114..17674
                     /locus_tag="VU722_001577"
     CDS             17114..17674
                     /locus_tag="VU722_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772514.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDAQGNCCDDLRYGLLRSEWEVI"
     gene            17674..18252
                     /locus_tag="VU722_001578"
     CDS             17674..18252
                     /locus_tag="VU722_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU1772515.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQDLLDNFHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQHQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            18245..20896
                     /locus_tag="VU722_001579"
     CDS             18245..20896
                     /locus_tag="VU722_001579"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU1772516.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            20991..22088
                     /locus_tag="VU722_001580"
     CDS             20991..22088
                     /locus_tag="VU722_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HEU1772517.1"
                     /translation="MAQNKLVRRNFDISFNELYDMYNDGELVIKPEFQRLFRWSLTQQ
                     SLFIESLLLDMPIPPIYVDEQEDGRYVLVDGLQRISSYLNFRGITLDSPELTAIDPDD
                     DDCEIDFERVEPGFQLSGCEIIDDLNGKEFDELSIEEKRQLKRTFIRVEVLTKENPKE
                     IKYHMFKRLNSGGALLSKQELRNSNIRMIDEKFINFINELANSEDFVELTHYMTESDK
                     QQMKRAEVVLRFFLFKNKFINDNPDVRMGFLDDELTTYLEEVSSQKFPFEYETEKENF
                     LSLVSYLKNHFGSVIFSGISKNNTISKRFVQYNYDGFMQYFSKESNRDSSITIDKINE
                     IKNSDEYKQYRTGGLENSRKRVEVIAGKVNE"
     gene            22081..22824
                     /locus_tag="VU722_001581"
     CDS             22081..22824
                     /locus_tag="VU722_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772518.1"
                     /translation="MSDIRDSLDKILAVSIDSIKDEQNFLNLVLSDSPEGNILKELAI
                     FKDNGALYKLIFSVYATFEYTIKECCNTALLTIDKNSLDSLTDELQMLTFRQKLDELR
                     KKIIEKREDNTVIKPLTDLHIKIKQQTEFNSNENMIDTKSNLNFNNFTEILEIFHFDK
                     KKYKSYSIIIDSIITYRNMIAHGNRKDLTEINIRQYIPGNYKIITLHKENNRLYFEDL
                     CSDMINLLKLFCQDLTDYVNEQKYLRQDK"
BASE COUNT         7160 a         4083 c         5044 g         6638 t
ORIGIN      
        1 tggagtgaaa tatgggaaaa ttctaggacc atggggcgct gcaataggag gagcagtggt
       61 ttgtggatat ttagcctata ccgctacatc ataaaaatga aagctaaatt ttatgaaggc
      121 tatattcttt attattctct tcgcttttca aacctatctt atttatctat ccataagtat
      181 ctctgataaa aaacaaaaga ctattgaatt aacatcattg aattgttttg tcatattatt
      241 tctaatctat gataaattaa tttttctctt tattgcctat gtttttttga taatttttat
      301 attaaacttg ttccgtaact gaaaagtgac atactatatg aatacaaaaa tgatgtcaca
      361 attttctgtt atggataatg aaatgcttgc ttgcgttgaa ggtggagata ttgattgggg
      421 aagaaaaatt agttgtgcag caggggttgc atatggcgca attgatgggt gtgtaacaac
      481 ggtttgacat ttctattggg accatttgct ataggaatag gtgtaactgg tgctgcaggt
      541 ggagctatac ttggaggtgt agcctatgca gcaacatgtt ggtggtaatt atggatttta
      601 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
      661 gaaaaatatt ttcaaaatct cccaaaaagg atacagatag taccccctaa aaaataaatt
      721 tctcccctgt atttgctagc ttaatttaca ggggagtttc tttaattttg tttcgcctgt
      781 caaaatgata tgtgatagca ggatgaaaag tctacaaaca agttggtatc aatacaatat
      841 aaagaggaaa gtatgttttt catgcttgct ttttttaatt tttacaattc aagaggtttt
      901 gatgaccatt tatgatttga gtgatccaag gtcaaaataa gtgctatact agcagtgtaa
      961 atgttcttgc tcaactaaga taaagcacac atttaggagg aaatcttatg aagaaaaaaa
     1021 tactgattat tttcgttctg tatctaatca tgtccatctt tctatatccg cttagggaga
     1081 gtgcttggta tcagctattt tataccatag cctatgtgat tgcagttatg atctattttg
     1141 ctatcaataa aaagaaagga gaaaagaaat gaaaattttt cttgctaaaa aacggaacat
     1201 cttccttgcg agattgttct taggtcagtt gcccttgctt gtctctactt atctatttct
     1261 atctcgtcag tttttaaatt tttccttagt tttccaattt tttttagtgg ttattaactt
     1321 agcttctatt ttggtcactg tttacctcac tagggaaatg cggataaaag agtttgaaga
     1381 cgatgatttg gttagtccta gaactaatca actcatgttc atcggcttga caggttttat
     1441 gtctattatt tgtttgtata gagggatcac agcaggagaa tcctaccaac aaataattgc
     1501 ctacattggc gctattctct gcttgaccat catgcttctg ctcatttggg gattgaagta
     1561 ttataaaaag tagagcttaa taaagtataa aggggtaagt gtttttgaaa tacttaccct
     1621 tttataatga agtttttgca attcaagatg tttcgatgac catttaagat ttagatgaat
     1681 ttgtaatctt aaataaggta agataaagat aacaaatgta aaggagtatt cttatgaaga
     1741 aacaaaagat aaaatcgcta ttacttgtac cacttgtatt tgcatctatt actgcaggtc
     1801 ttgcatatgc agaagaacag cctactactt catctaccca ggcgaatgat agttctcttg
     1861 tggcgccaga tttgccatcg gctaaggaaa aggtggagca taagccttct gttgtaaccc
     1921 cagaagagta tgagaagaat gttacggact ttaaaaagat agatattgaa gctgttcgtc
     1981 aatcttttac aggggatcaa ttggaacata ctatttattt tggtagaaaa acttgctctc
     2041 attgtcgtca attttctcct gaattgaaag aatttaataa cttgattgaa aagaagttag
     2101 agtattatga tttggatggt aaggattttg atggggaagc gagagagttt ctattttaaa
     2161 aaagtcggta ttccaggaac accaacaatt ttgtatttaa gaaatggaca tccgacatct
     2221 ggatgggttg gtggcggagc aactgcacaa caggtgtatg attatatgta ttcgagaaac
     2281 tcacctaagc aaacggagac agtgaaatct tctgaggaaa cagtaactga aagtgtccgt
     2341 gatgagaata ctagaagtga cagcatgaat attagtgata aagttgtaag tgacagcaaa
     2401 ggtatgagtg ataaaaaaag aactgaaatg aaaatatcca atgctaatag tgaaaatagt
     2461 gggaaagtgg agagtacaaa ctcaacttct gaagctaaaa ctactcaatc tggcaattta
     2521 gcaatgttag acaataagaa tcaattggaa actctcaaac ctatttttga tgctgctcaa
     2581 gaaaataaaa cttctttaac tgatgttaag gatgctgatt atgtaagcga atctattact
     2641 tcgaatgaaa aattattact gaaaacaggc gaggaagaaa gttaccaact gattcgacta
     2701 gctgtcgcgt tttttatggc ttctataatg attaaagtga aacaaaaaat tcataaataa
     2761 aaatagatgg taaacaggtg aaatgatact atttgtttgt aataacatat agctagaatt
     2821 tgcctataga caagagtgaa agggcaagta tgttgttaat gcttgctttt taaatttttt
     2881 aacaattcaa gacgtttcga tgacaattca agatttggat gaaaaaaatt aataaacgat
     2941 gatatactaa acttgtcaag gttgcaacag gacaaaaatt aaacataaaa aaggagatat
     3001 tcgtcatgga tacaaaaatg atgtcacaat ttgcagttat ggataatgaa atgcttgctc
     3061 gtatagaggg tggggatgtc tctgatattt atagagggta cgctaatcag gtaagtccat
     3121 tcggttctta ccctcctata ttaaaaaatt caggtccttt tccagtaagt ggttactgcc
     3181 cgcgcggtta tcatgaccgt ggttatatag gagcaggttt tcatttatgt ggaatatagg
     3241 ctgaaataca agaaatgagg aagaatttct atgaaaaagt atcagcttgt tttcaaaata
     3301 agtgcagtct tgtcttacct atttttcgta tttggtcttt ctcagttaac tcttatcgtc
     3361 caaaatcatt ggcaattttc ttctcaggta ggaaattttt tctggattag aaatatcttg
     3421 agtctgctat ttagcggagt catgatttgg attctggtta agacaggcca tggctatctc
     3481 tttcgcattc caagaaaaaa atggctttgg tattctattt tgacagtatt agtggtagtg
     3541 ctccatatct cttttaacgt tcagacagct aaacatgttc agtcaaccgc tgaaggttgg
     3601 gccgtattga tcggttatag tgggaccaac tttgctgagc taggtatcta tgtaaccctg
     3661 tttttcctga ctccactaat ggaagagttg atttataggg gattactgca acacgccttc
     3721 tttaagcatt cgcgatttgg ccttgatttg cttcttcctt ccattttgtt tgctcttcct
     3781 cattttttga gtctgcctag tctgttagat atcttcgtct ttgcaacatt tggaatcatc
     3841 tttgccggtt tgacccgcta taccaagagt atttatccat cctatgcggt gcatgtgatc
     3901 aataatattg tagcgacctt cccgtttttg ctcacttttc tacatagggt cttggggtaa
     3961 aaaaaacaaa aggcttgctt ttcagccata gaggaggtca tcatgtataa acacttattt
     4021 ttcctagatt ccaaaacttt agatcggttg acaccctata ttatagtctt ggcttctgac
     4081 accattgctt ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt taatttccta
     4141 aattccatgc tagctttaat ggctatattc ataggggctg gctatgtggt cggattttgg
     4201 ttgctaaaat ggtttgtttt ggaaaggcta gatctaaaga atgacgtgta ggaagtctgt
     4261 ttgttgagga ggataatttt atggagtttt ttgataaatt tcatgccttg tgttttggat
     4321 ttttagtact aataattgtc attacagttc cttatacgat taaccatggg gatttttttc
     4381 aaaatgaatc tgcattgatt attgtaagtc ttcttgtaac ctcgctgagt gttgcttatg
     4441 ctagaaagtt tgaaatgatt tcttttggga tgttaagcaa gaaacaactt ttgcttttca
     4501 ttgcaatctt tcttctaagt gtacttgaga cgctggttta tattcatttc ttcgctgttt
     4561 cttctggctc aggggtccaa cacttggcgg aagtcagcag aggaatttcc ctgtctttga
     4621 ttttgactac ctcagttttt ggccccatcc aggaggaact cattttcaga ggacttcttc
     4681 aaggtgcggt ttttgacaat tcttggttag ggcttgtgct aacttcctct ctcttttctt
     4741 tcatgcatgg accttctaat gtcccttcgt ttatttttta tctacttggg ggtttgttgc
     4801 tgggctttgc ttataaaaag agccaaaacc tatgggtttc tactctagtc catatgcttt
     4861 acaacagttg gccactctta tattatttat aaaaatcatg aaaaggtaag taggagattg
     4921 tgcttacctt tttctttcta taatgataac ccaaaccact ccagaggctt ttctttgaga
     4981 atcgggttag agtggttgac gaataggcca aaaactagta gaatagtaag gaaactttat
     5041 acggaggaaa gaaatggatt tgggtgataa tgagctaaca ctgactccca tacctgggaa
     5101 aagtggcaag gcttatatgg gtagctatcc tgatgggaag cgcatctttg taaaaatgaa
     5161 cacctctcca atcctacctg gtctagctag agaacaaatt gctccacaat tattatggag
     5221 tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa tggttgacag gcaagatatt
     5281 gaccccctat gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc
     5341 acgtccgttg atgacacaat tgagtcgttt gggctatgcc atggaaacac ctgtagattt
     5401 actacagtct tggcaggaaa cggctccaga tgctttgcgt aaaaatcatt ttatcagtga
     5461 agtgatggct gatttacgtc agactattcc aggatttaga gaggaccatg cgaccattgt
     5521 ccatggagat gtacgacata gtaattggat tgagacagat agtggcttga tttatttagt
     5581 agattgggat tcggttcgct tgaccgatcg catgtttgat gtggcccata tgctctgcca
     5641 ttatatttca gaacatcagt ggaaggaatg gttgacctac tacggttaca agtacaatca
     5701 aacggtatta agtaaattgt attggtatgg tcaattgtct tatttgagtc agatttccaa
     5761 gtattatatg aaccaagatt tagaaaatgt caatcgggag attcatggtt tgcgtcattt
     5821 ccgagacaag tatggaaaga gaagatgaga gttagaaatc gtaaaggggc aacagaatta
     5881 ctagaggcaa atccccagta tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg
     5941 gacttgtttg gcaatgataa tcccattcat gtggaagttg gaagtggaaa gggtgccttt
     6001 gtttcaggta tggccaagca aaaccctgac atcaactata tcgggattga tattcaaaag
     6061 tctgttttga gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa catcaagctc
     6121 ttgtgggtag atggttctga cttaactgac tactttgaag acggtgagat tgatcgcttg
     6181 tatctgaact tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg tttgacctac
     6241 aagaccttct tggatacctt caaacgtatc ttgcctgaaa atggagaaat tcatttcaag
     6301 acggataacc gtggcttgtt tgagtacagt ttagtgagct tttctcaata tggcatgaaa
     6361 ctcaatggtg tctggttaga tttgcatgcc agtgattttg aaggcaatgt catgacagaa
     6421 tacgagcaaa aattctcaaa caaggggcaa gttatctacc gagttgaggc agaattttaa
     6481 gagatagcct aaaattaggc tgtacaagtg cttttgcttt acataagttg gcaaacgtgc
     6541 tatactgata gtaagaatat gaaaagtgag gcggggaaat atcttcgcct cttgcttatg
     6601 aggaggtgga cgcaatcgca acaatcgtag aattagtcag agaagttgta gaacctgtca
     6661 tagaagctcc ttttgaactc gtggatatcg agtatggaaa gattggcagt gacatgattc
     6721 tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa cgacacggca gacttgacag
     6781 aaatgatcag tcctgtccta gacaccatca agccagatcc cttcccagaa caatatttcc
     6841 tagaaattac cagtccaggt ttggaacgtc ctttgaaaac caaggatgcc gtcgctggag
     6901 cggttggaaa atacatccat gtcgggctct accaagccat cgataagcaa aaggtctttg
     6961 aaggaacctt gttggccttc gaagaggacg agttgactat ggaatatatg gacaagacgc
     7021 gtaagaaaac cgtccaaatt ccatacagtt tagtatcaaa agcacgttta gcagttaaat
     7081 tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg aagaaaacat gagtaaagaa
     7141 atgctagagg ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga agatatcatc
     7201 gacgcagtag tagagtcgct tcgttccgct tatcgcagac gctatggtca gtcagacagc
     7261 gtagctattg acttcaacga aaaaacaggt gactttacag tttatactgt ccgtgaagtt
     7321 gttgatgaag tatttgatag ccgtttggaa atcagcttga aagatgctct tgccattaat
     7381 tcagcttatg aacttggaga caaaatcaag tttgaagaag caccagctga gtttggtcgt
     7441 gtagcagccc aatctgccaa acaaaccatc atggaaaaaa tgcgcaagca aacacgtgcc
     7501 atcacttaca atacttacaa agaacatgag caagaaatca tgtctggtac agtagaacgc
     7561 tttgacaacc gctttatcta tgtcaacctt ggtagcatcg aagcccaatt gtcaaaacaa
     7621 gaccaaattc ctggagaagt ttttgcttct catgatcgta tcgaagttta tgtttacaag
     7681 gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc gtagccatcc agaaatgatc
     7741 aaacgtttga tggagcaaga aattccagaa gtttatgatg gaactgttga aatcatgagc
     7801 gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc gtagccacaa tccaaacgtg
     7861 gatgctatcg gtacaatcgt tggacgtggt ggtgctaata tcaagaagat tactagcaaa
     7921 ttccacccag ctcgttacga tgctaaaaat gaccgcatgg taccaatcga agaaaatatc
     7981 gatgttatcg agtgggtagc agatccagct gaatttatct acaatgccat cgctcctgct
     8041 gaggttgacc aagttatctt tgatgaaaac gacagcaaac gtgccttggt ggttgttcca
     8101 gataacaagc tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt ggcggctcac
     8161 ttgactggtt accgtatcga tatcaagtct gctagcgaat ttgaagccat ggaagacgct
     8221 gcttcagtag agttggaagt agaaaacgat actgtagaag aataaaagct gctagaggag
     8281 ggaaagatga aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa cgaagtgatt
     8341 gataagcgtg atttgctccg cattgtcaag aacaaggaag gacaagtctt tattgatcct
     8401 acgggcaagg ccaatggccg cggcgcttat atcaaactag acaatgcaga agccctagag
     8461 gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg aagtggaaga aagcttttat
     8521 gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg acttgaataa
     8581 gcaaaagata agtaatctct tggggcttgc tcagcgagca gggcgcatca tatcgggtga
     8641 agaattggtg gtcaaggcca ttcaagacgg caaggccaag ttggtctttc tagctcatga
     8701 tgctggaccc aatctgacca agaagattca agataaaagt cattattatc aagtagaaat
     8761 tgtaaccgtg ttttcaacac tggaattaag catagcagtc gggaaatcga gaaaggtttt
     8821 ggctgtaaca gatgctggat ttacaaagaa aatgaggtct cttatggaat agaagaggag
     8881 gacatgattt gtctaagaaa agattgtacg aaatcgcaaa agaacttgga aaagaaagta
     8941 aagaagttgt agcgcgtgca aaagagttgg gcttggatgt gaaaagccac tcatcaagtg
     9001 tggaagaagc tgtcgctgca aaaattgctg ccagctttaa gtctgcagct gctccgaaag
     9061 tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa gaaagccgaa aaatctgagc
     9121 cagctaaacc agctgtagct aaggaagagg caaaaccggc tgagccagtt gctccgaaaa
     9181 cagaaaaagt agcagcgaaa ccgcaaagtc gtaatttcaa ggctgagcgt gaagcccgtg
     9241 ctaaagagca ggcagaacga cgcaagcaaa ataagggcaa taaccgtgac caacaacaaa
     9301 acggaaaccg tcagaaaaac gacggccgta atggtggaaa acaaggtcaa agcaaccgcg
     9361 acaatcgtcg ctttaatgac caagctaaga agcagcaagg tcagcaaaaa cgtagaaatg
     9421 agcgccgtca gcaagaggac aaacgttcaa atcaagtggc tccacgtatt gactttaaag
     9481 cccgtgcagc agccctaaaa gcagagcaaa atgcagagta cgctcgttca agtgaggaac
     9541 gcttcaagca gtatcaggct gctaaagaag ccttggctca agctaacaaa cgcaaggaac
     9601 cagaggaaat ctttgaagaa gcggctaagt tagctgaaca agcacagcaa gttcaagcag
     9661 tggttgaagt cgtccctgag aaaaaagaac ctgcagtgga tacacgtcgt aaaaaacaag
     9721 ctcgaccaga caaaaatcgt gacgattatg atcatgaaga agatggtcct agaaaacaac
     9781 aaaagaatcg aagtagtcaa aatcaagtga gaaatcaaaa gaatagtaac tggaataaca
     9841 acaaaaagaa caaaaaaggc aataacaaga acaaccgtaa tcagactcca aaacctgtta
     9901 cggagcgtaa attccatgaa ttgccaacag aatttgaata tacagatggt atgaccgttg
     9961 cggaaatcgc aaaacgtatc aaacgtgaac cagctgaaat cgttaagaaa cttttcatga
    10021 tgggtgtcat ggccacacaa aaccaatcct tggatgggga aacaattgaa ctcctcatgg
    10081 tggattacgg tatcgaagct aaacaaaagg ttgaagtgga taatgctgac atcgaacgtt
    10141 tctttgtcga agatggttat ctcaatgaag atgaattggt tgagcgtcca ccagttgtta
    10201 ctatcatggg acacgttgac cacggtaaaa caaccctttt ggatactctt cgtaactcac
    10261 gtgttgcgac aggtgaagca ggtggtatta ctcagcatat cggtgcctac caaatcgtgg
    10321 aaaatggtaa gaagattacc ttccttgata caccaggaca cgcggccttt acatcaatgc
    10381 gtgcgcgtgg tgcttctgtt accgatatta cgatcttggt cgtagcggca gatgacgggg
    10441 ttatgcctca gactatcgaa gccattaacc actcaaaagc ggccaacgtt ccaatcatcg
    10501 tagccattaa caagattgat aaaccaggtg ctaacccaga acgcgttatc ggtgaattgg
    10561 cagagcatgg agttatgtca actgcttggg gtggagattc tgaatttgtt gaaatctcag
    10621 ctaaattcaa ccaaaatatc gaagaattgt tggaaacagt ccttcttgta gctgaaatcc
    10681 aagaactcaa ggcagaccca acagtgcgtg caatcggtac ggttatcgaa gcgcgcttgg
    10741 ataaaggaaa aggtgcggtc gcaacccttc ttgtacaaca aggtaccttg aatgttcaag
    10801 acccaatcgt tgtcggaaat accttcggtc gtgtccgtgc tatgaccaac gaccttggtc
    10861 gtcgtgttaa agttgctgga ccatcaacac cagtctctat cacaggtttg aacgaagcac
    10921 cgatggcggg tgaccacttt gccgtttacg aggatgaaaa atctgcgcgt gcagcaggtg
    10981 aagagcgtgc caaacgtgcc ctcatgaaac aacgtcaagc tacccaacgt gttagccttg
    11041 aaaacctctt tgataccctt aaagctgggg aactcaaatc tgttaatgtt atcatcaagg
    11101 ccgatgtaca aggttctgtt gaagcacttt ctgcctcact tcaaaagatt gacgtggaag
    11161 gtgtcaaagt gactatcgtc cactcagcgg tcggtgctat caacgaatca gacgtgaccc
    11221 ttgccgaagc ttcaaatgcc tttatcgttg gtttcaacgt acgccctaca ccacaagctc
    11281 gtcaacaagc agaagctgac gatgtggaaa tccgtcttca cagcattatc tacaaggtta
    11341 tcgaagagat ggaagaagct atgaaaggga tgcttgatcc agaatttgaa gaaaaagtta
    11401 ttggtgaagc ggttatccgt gaaaccttca aggtgtctaa agtgggaact atcggtggat
    11461 ttatggttat caacggtaag gttgcccgtg actctaaagt ccgtgttatc cgtgatggtg
    11521 tcgttatcta tgatggtgaa ctcgcaagct tgaaacacta taaagacgac gttaaggaag
    11581 ttacaaacgg ccgtgaaggt ggattgatga tcgacggcta caatgatatt aagatggatg
    11641 atgtgattga ggcgtatgtc atggaagaaa tcaagagata agattttttg ctcctttctt
    11701 aggtggtgag ggacgcaagc aaaccgatgg tttcattgct tatttttgag cctagggtct
    11761 caaaaatccc ctgtgatggg actgataaat cagttccatc actttcacca cggcgaaaga
    11821 agcagatgac ttcaaattga acttcgtttc aatttaaact gaaaatcaag aagtttaaaa
    11881 tagctaggtc tgctggccta gcttttggtt caaagtagag aaaggaatat catggcaaat
    11941 catttccgta cagatcgtgt gggcatggaa atcaagcgtg aagtcaatga gattttgcaa
    12001 aagaaagtcc gtgatccacg tgtccaaggt gtgaccatca cagatgttca gatgctgggt
    12061 gacttgtctg ttgccaaggt ttattacacc attttgagta accttgcttc ggataaccaa
    12121 aaagcccaaa tcgggcttga aaaagcaact ggtaccatca aacgtgaact tggtcgcaat
    12181 ttgaaattgt acaaaatccc agatttgacc ttcgtcaaag acgagtccat cgagtatgga
    12241 aacaagattg acgagatgct acgcaatctg gataagaact aaagaagagg ggttgcccct
    12301 cttttttggt ggaggaaaat aggttgaatt tgaaatggaa aaatattctt ttaaaatata
    12361 ttgaaactag aatagtacgc ctctacttct aaaacattgt tagaaatcga tttgactgtc
    12421 ctgatcgatt tgtcctgttc ttgttttatt ttactataaa aaaggggttc tgtatttttt
    12481 aatgttatct aattagaaaa tgcttttttt gtaggaaata taatatgata aggtgcaaaa
    12541 aagaaataag gagtttgtat atggctgaac aagacttagc tatgcaagta ttacaacaag
    12601 tggtaaaact accagttgtt aaggttgatc gttcgaaatt tttagtggat aagttttcca
    12661 aagaattggg tccacaggac attcctacct tattggaaca aggtccaacg tctctcttat
    12721 ctcaagaaat cttagatcga gtggctaatg cctgtattag ggataatgtt ttattagcga
    12781 gtgggacttc tgttttggca ggattacctg gagggcttgc tatggcaatt accattccag
    12841 cttatgtggc tcaattttat ggtttctctc tgaaattggc ccaagaatta ggttatattt
    12901 atggttatga ggatctttgg gcttcacgtg aggagttgag tgaagatact caaaataccc
    12961 tcttgcttta tctaggcgta atgttagggg tgaatggaac cgctgctttg tttgctacgt
    13021 gctggtggta taacaattgc caaacaggta atgaaaacag tgcctaataa agctttaaca
    13081 aagacgcttt ggtaccctat tttgaaaaaa gtcttaagaa tatttggtgt gaatcttacc
    13141 aagggagggc tggccaaagg aatagggaaa tttattccta tcttgggtgg tatcatttca
    13201 ggtggtttaa cctttgcaac tatgaaacca atgggggaaa gcttgcagaa agaattatcc
    13261 aagctagtca actatagtga agttcaatat caagaagatg ttgaaacaat ccgaaaagag
    13321 gctgaaatca tcaaaggaga gtaatatgaa tcctatcaaa gcttttgcta aaatttatgg
    13381 taattacttt ttgaccgtgc aaggtgtaaa agtgatgaaa acgataaaga aagctgacca
    13441 tgtcgttgtt ggtctgggca aactttttat tgcagataag ctaatggata cggctcggtg
    13501 gctcattaag ccagaggaga gagaatgaaa tttttttggt cttcttgcta ttctttttat
    13561 caaaccgatt attgggattg tgaaattctt ttggatgatc atttcttttg cagttcaatt
    13621 gctgttttac aagatattat ttaagatatt ggattggctc tttaaactta tctagatggt
    13681 aatccaagtc gcagagagct agcaggaact ccactgctag ttttttaatc tctctccata
    13741 tggtataata taagcagtaa aatcatttta tactcttcga aaatctcttc aaaccacgtc
    13801 agcttcacct tgcagtatat atgttactga cttcgtcagt tctatccaca acctcaaaac
    13861 ggtgttttga gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt
    13921 agaacatata atggaggtcg tcatggacaa tatcatcgat gtgtcaattc ctgttgcaga
    13981 agtggtggac aagcatccag aagtcttgga aattctagtg gagctgggtt ttaaacccct
    14041 tgccaatccc ttaatgcgca atacagttgg tcgtaaagta tcacttaaac agggttctaa
    14101 gctagcagga actcctatgg acaagattgt acgcacactg gaagcgaatg gctacgaagt
    14161 gattggatta gactaatgac agatgaacgg attcatgtcc tacgggatat tttattagaa
    14221 ttgcataatg gcgcctctcc tgagtcggtt caggagcgtt ttgatgcgac ctttgcgggt
    14281 gtctcagcca ttgagatttc ccttatggag cacgagctga tgaactcaga ctcaggtgtc
    14341 acctttgaag atgttatgga actctgtgat gtccatgcca atctttttaa aaatgctatc
    14401 aaaggtgtcg aagtttcaga tactgagcat ccaggtcacc cagttcgtgt cttcaaagaa
    14461 gaaaatctgg ctctccgtgc ggccttgatt cgcattcgta gattgttaga tacctatgag
    14521 tctatggaag acgaggaaat gcttgcggag atgcgcaagg gcttggtgcg tcagatgggg
    14581 cttgtggggc aatttgacat ccattaccaa cgtaaggaag aactcttctt tcctatcatg
    14641 gagcgctatg gacacgattc acctcccaaa gttatgtggg gagtggatga tcagattagg
    14701 gaactctttc aaacagctct aacgacagcc aagtcactac cagaagtgtc aattagcagt
    14761 gtaaaggaag cttttgaagc ttttgcgaca gagtttgaaa gtatgatttt caaggaagag
    14821 tccatcctcc tcatgattct ccttgagtct tttactcagg atgactggct tcagattgcg
    14881 gaggagagcg atgcctatgg ctatgccatc atccgtccgt cagagaaatg ggtgccagaa
    14941 cgacagagct ttattgagga aaagattgca gaggaacctg tacagctaga tacggcagaa
    15001 ggtcaagttc aacaagtcat agatacgcca gaaggccatt ttaccattac ctttacccct
    15061 aaggaaaagg aagctgtgct ggaccgccat agtcaacagg cttttggtaa tggctatctt
    15121 tcagtcgagc aggccaatct catcctcaat catctcccta tggagattac ctttgtcaat
    15181 aaagaagata ttttccagta ttacaatgac aatacgccag ctgatgagat gattttcaaa
    15241 cggacgccgt cccaagtcgg gcgcaatgtc gaactctgcc atccgcctaa gtacttggac
    15301 aaggtcaaaa ctatcatgaa ggggcttcgt gagggaagca aagacaagta tgaaatgtgg
    15361 ttcaagtctg agtcgcgagg taagtttgtc cacatcacct atgctgcagt acacgatgaa
    15421 gacggagaat tccaaggagt gttggagtat gttcaggata tccagcccta ccgtgagatt
    15481 gatacggact attttcgtgg attagaataa ggagaaaaaa tgagttacga acaagaattt
    15541 atgaaggaat ttgaagcttg ggtcaatacc caaatcatga ttaacgatat ggcgcacaag
    15601 gaaagtcaaa aagtttacga agaagaccag gacgagcgtg ccaaagatgc catgattcgc
    15661 tacgagagtc gcttggatgc ttatcagttc ttgcttggta agtttgaaaa cttcaaagca
    15721 ggcaagggat tccatgattt gccagaaggc ttgtttggtg agcgaaatta ttaaacgaga
    15781 aagattcttg atttttcact aaaatcttga tagaatgttt atgttaaatc cttgtcagag
    15841 cagggatttt ttattgaaag gattttatca tgtcaaagaa actcaatcgt aaaaaacaat
    15901 tacgaaatgg cctccgtcgc gcaggtgcct tttcaagtac tgtgactaag gttgtagatg
    15961 agacaaaaaa agtcgtgaag cgtgcagaac agtcagcaag cgcagctggt aaggctgttt
    16021 ctaaaaaagt tgaacaagca gtagaagcta ccaaagagca agctcaaaaa gtagctaatt
    16081 ctgtagaaga ttttgcagca aatttgggtg gacttccact tgatcgtgcc aagactttct
    16141 atgatgaagg aatcaagtct gcttcagatt tcaaaaactg gactgaaaaa gaactccttg
    16201 ccttgaaagg aatcggccca gctaccatca agaaattgaa agaaaatggc atcaagttca
    16261 agtaattttt cttgagcctt gcatttccga aaaaatcttg ctacaataga gccattagag
    16321 gtgttttgaa tcccacattt tacagaaagt ggcggcgctg agaagtccac aaatgtgtca
    16381 aaactggttg ctaatggatg aaaaattgaa ataaaagtgt ctttttgctt taaagacgag
    16441 agttgcgggc aactgcccga aattgggtgg taccgcggat aaacacattc gtccctgtca
    16501 tgtagatggc agggcttttc ttttacgtct tagtcaaagg gggttgttat gaagcaatct
    16561 tttaacacaa gtaaactata ttatggtttt cctgttttta ttttaggata tcaagattag
    16621 aattttggct ataacatcac gacctgtagt tcctcttata gtctaggaga ttgggttgtg
    16681 attggagtcg ttgcgagaga gaatgccgca gagcagatca aacagtatca aaaatttact
    16741 gtgaatattt ctgatgaaac ttctatgctt gcgatggagc aggctggttt tatcagtcat
    16801 caggagaaat tggaacgttt gggagtgcat tatgaaattt ctgaacgaac tcagactcct
    16861 attttagacg cctgtccact tgttttagat tgtcgggtag ataggattgt tgaggaagac
    16921 ggtatttgcc acatctttgc caagattctt gagcgacttg ttgttccaga actcctggat
    16981 gaaaagggac attttaaaaa tcaactgttt gccccaacct atttcatggg agatggatat
    17041 cagcgcgttt atcgctatct ggacaagcgt gtagatatga agggcagttt catcaaaaaa
    17101 gcgaggaaga aggatggcaa gaactgagct gccagataaa atcgaaacag aacgtctcgt
    17161 tttacgagtc cgtactgtgg cggatgctga ggatatcttt gactatgcta gtttgccaga
    17221 ggttgcctat ccagcaggtt ttcctccagt caagaccttg gaagatgaga tttattatct
    17281 ggagcacatt cttccggagc gtaatcaaaa ggaaaatctc ccagcaggct acgggattgt
    17341 cgtcaaagga acggataaga tcgttggctc tgtcgatttc aaccatcgcc atgaagatga
    17401 tgtgctggaa atcggctata ccttacaccc agactattgg gggcgaggtt atgttccaga
    17461 agcagcgtgt gccttgattg atctagcttt taaagaactt ggtcttcaca agattgaact
    17521 aacttgcttt ggatataacc ttcaaagtca acgagtctcg gaaaagcttg gctttaccct
    17581 cgaagctcgc ataagagacc gcaaagatgc tcaaggcaac tgctgtgatg atttgagata
    17641 tggcttgctg aggagtgagt gggaggtgat ttgatgcatc ttttcatcat tggtgctcca
    17701 gcatcaggaa aaatgaccat tggtcaagaa ttatctcgac tgacggatgc taccctattt
    17761 tataaccatc aagccattga ttttgcacta gagatctatc aggattatac cgaggagatg
    17821 tgggaatttg ttcgtggaat taccttttct ttccttggag caagtgcaag aaatcagcga
    17881 tcagtaattt taacagacgt aattgatttt tcaaatcagt accagctgat gtatttaaag
    17941 caaattcagg atttattgga taactttcat caagagattc tgtttgttga attggaaaca
    18001 agtcttgaag agtgcatacg tcgaaatcga acggagaatc gattaaagca caaaccctta
    18061 aaacgacata ttgaggtatc tgaaagagaa attttagaga ccgctgaaac acttcaatta
    18121 aattcccaac atcaaccgaa tgagttgcac cactacttta aaataaataa tacgaatttg
    18181 tctgcagaag aagctgctaa gcaaattcaa aataaaataa acaaaataga gaaaggacac
    18241 acacatgtct aaagaacttt cacctaaata caatccagcc gaggttgagg ctggtcgtta
    18301 ccaaaaatgg cttgatgcgg atgttttcaa gccttcaggc gatcaaaagg ctaagcctta
    18361 ttcaatcgtg attccaccac caaacgtaac tgggaaactt caccttggtc acgcttggga
    18421 tacgactttg caggatatca tcatccgtca aaaacgcatg caaggctttg ataccctttg
    18481 gcttccaggt atggaccacg ctggtattgc gactcaggct aaggttgagg agcgcttacg
    18541 tggtgagggt attacgcgtt atgacctagg tcgtgagtct ttcttgacga aggtctggga
    18601 atggaaagac gaatatgcca ctaccatcaa ggaacaatgg ggcaagatgg ggctttctgt
    18661 agactattct cgtgagcgtt tcactcttga tgaaggtttg tcaaaagctg ttcgtaaggt
    18721 ctttgtggat ctttacaaga aaggctggat ctatcgtggt gagtttatca tcaactggga
    18781 cccagcagct cgcacagccc tttctgatat tgaggtgatt cacaaggatg tagaaggtgc
    18841 cttctaccac atgaattaca tgctggaaga tggttcacgc gcccttgaag ttgctacaac
    18901 tcgtcctgag actatgtttg gggacgttgc ggttgcggtt aatccagaag acccgcgcta
    18961 caaggacttg attggtaaaa acgtcatcct tccaatcgct aataaactca tcccaatcgt
    19021 tggagatgag cacgcagatc ctgagcttgg tacaggtgtc gtgaaaatca cacctgccca
    19081 cgatccaaat gacttcttgg ttggccaacg tcataacttg ccacaagtca acgtcatgaa
    19141 cgacgacgga actatgaatg agcttgcctt tgaattttca ggcatggatc gttttgaagc
    19201 tcgtaaggca gtcgttgcta agttggaaga aatcggtgcc cttgtcaaaa tcgaaaaacg
    19261 tgtccacagt gttggtcact cagaacgtac aggtgtcgta gttgagccac gcttgtctac
    19321 tcaatggttc gtcaagatgg accaattggc taagaacgcc attgccaacc aagacacaga
    19381 ggacaaggtc gaattctacc cacctcgttt caacgatacc ttccttcaat ggatggaaaa
    19441 tgtccacgac tgggttatct ctcgtcagct ttggtggggt caccaaatcc ctgcctggta
    19501 caatgctgat ggtgaaatgt atgtcggcga agaagctcca gaaggtgacg gatggactca
    19561 ggacgaagac gtcttggata cttggttcag ttctgccctc tggccatttt caaccatggg
    19621 ctggcctgaa gtcgactcag aagactttaa acgttatttc ccaacttcaa ccttggtaac
    19681 aggttacgac atcatcttct tctgggtgtc tcgtatgatc ttccagtcct tggaatttac
    19741 tggtcgtcag ccattccaaa acgtgcttat ccacggtctc atccgtgacg agcaaggacg
    19801 caagatgtct aaatctctcg gtaacgggat tgacccaatg gatgtcatcg agaaatacgg
    19861 tgctgatgcc cttcgttggt tcctttcaaa cggttccgca ccaggtcaag acgttcgttt
    19921 ctcttacgag aaaatggatg cttcatggaa ctttattaac aaaatttgga acatttctcg
    19981 ctatatcctc atgaacaatg aaggtttgac gctggatgtg gcgcatgaca atgtcacaaa
    20041 agttgcaaca ggtgaggctg gtaatgtgac ggaccgctgg attctccaca atctcaacga
    20101 aaccattgca aaagttactg aaaactttga taagttcgag tttggtgtgg ctggtcatat
    20161 cctttacaac ttcatctggg aagaatttgc caactggtat gttgagttga ccaaggaagt
    20221 tctatacagc gacaatgaag acgataaggt cattactcga tctgttctcc tctatacgct
    20281 ggacaagatc cttcgtctcc ttcacccaat catgccattc gtgacagagg aaatctttgg
    20341 acaaatctca gaaggttcta tcgtgacagc tgcataccca actgttaatc tagcctttga
    20401 agaccttgct gcccacactg gtgtggaaag tctcaaagac ttgatccgtg ccgttcgtaa
    20461 tgcgcgtgcg gaagtaaatg tagcaccaag caaacctatc acaatccttg ttaagactag
    20521 cgatagtgac ttggaagcct tctttaacag caatgtcaac tacatcaaac gctttacaaa
    20581 tccagaacat ttggaaatcg catcaaccat ccctgcacct gaactggcta tgtcaagtgt
    20641 catcacagga gcagaaatct acctgccact ggccgatctc ctcaatgttg aagaagaact
    20701 agctcgtctc gacaaagaac tcgctaaatg gcaaaaagaa ctggacatgg ttggtaagaa
    20761 actctctaac gaacgcttcg tagccaacgc caaaccagaa gtcgtccaaa aagaacgtga
    20821 caaacaagct gactaccaag ccaagtatga tgcgaccgta gcacgtattg atgagatgaa
    20881 gaagttggtg aaataaacaa ttatataaat ttaataaaac acagtgtaaa aactgtgttt
    20941 ttatggtata atcaatatta taaatattta ttgaaagttg agactttttt atggcacaaa
    21001 ataaacttgt cagaagaaat tttgatatat cgtttaatga actttatgat atgtataatg
    21061 atggcgaatt agttattaag ccagaattcc aaagattatt tagatggtca ttaacacagc
    21121 aatctctctt tattgagtcc cttcttttag atatgcctat acctcctatt tatgtagatg
    21181 agcaagaaga tgggaggtat gttctagtag atggactaca aagaatttca tcttatctaa
    21241 atttcagagg cataacgtta gattctccag aattaactgc tattgatcca gatgatgatg
    21301 actgcgagat agactttgag cgagttgaac caggttttca attatcaggt tgtgaaatta
    21361 ttgatgattt gaatggtaaa gaatttgacg agttaagcat agaggaaaaa cggcaattaa
    21421 aacgtacgtt tattcgagta gaagtcttaa caaaagaaaa tccaaaagaa attaaatatc
    21481 atatgtttaa aagattaaat tctggtggag cattgctatc taaacaagaa ttaagaaaca
    21541 gtaatatacg catgattgac gagaagttca taaactttat taatgaactg gctaactctg
    21601 aagattttgt tgaattgaca cattacatga cagaatctga taagcagcaa atgaagagag
    21661 ctgaagttgt tttaagattc ttcttgttta aaaataaatt tattaatgat aatcccgatg
    21721 taagaatggg atttttagat gatgaactta cgacctattt agaagaagtt tcctcacaga
    21781 agtttccttt tgaatatgaa acagaaaagg aaaacttttt gagtttagtt tcgtatctta
    21841 aaaatcattt tggtagtgtt attttcagtg gtatcagcaa aaacaatact atttctaaaa
    21901 gatttgtcca gtataactac gacggtttta tgcaatattt ctcaaaagag agcaatagag
    21961 attcatcaat tactattgat aagattaatg agataaaaaa tagtgatgag tataagcaat
    22021 accgaactgg ggggcttgaa aattctagaa aacgcgttga ggtaatagca gggaaagtaa
    22081 atgagtgata ttagggattc tcttgacaaa attttagcag tttcaatcga tagtattaaa
    22141 gatgaacaga attttttaaa tttagtatta tccgactctc ctgagggtaa tattctaaaa
    22201 gaactagcaa tctttaagga taatggagca ttatataaat tgatattttc agtctatgct
    22261 acctttgagt ataccatcaa ggaatgctgt aatactgcct tactaacaat cgataaaaat
    22321 agtctagatt cattgacaga tgaactacaa atgctaactt ttcgacaaaa gctagatgaa
    22381 ttacgcaaaa aaataattga gaagagagaa gataacacag ttattaaacc acttacggac
    22441 ttgcatatca aaattaaaca acaaaccgaa ttcaatagca atgaaaatat gattgatacg
    22501 aaatcaaatc tgaatttcaa taattttaca gaaattcttg aaatatttca ttttgataaa
    22561 aagaaatata aatcctattc aattatcatt gattcaataa taacttatcg aaatatgatt
    22621 gctcatggaa acagaaagga tttaacggag ataaacatta gacaatatat tcctggaaat
    22681 tataaaatta ttactcttca taaagaaaat aatcgacttt attttgaaga tttatgtagt
    22741 gatatgatta atcttcttaa actattttgt caggatctta cagattatgt aaacgaacaa
    22801 aagtatttac gtcaagataa gtgaatatta ttttaaataa ttaaaaaaga acgacattct
    22861 aaaagttaaa ctaagaatat tatctttata gaataacata gaaacatggt gtaatgccgt
    22921 gtttt
//
LOCUS       DAVFJR010000033        22634 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVFJR010000033 DAVFJR010000000
VERSION     DAVFJR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.034"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            1..879
                     /locus_tag="VU722_001582"
                     /pseudo
     CDS             1..879
                     /locus_tag="VU722_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(945..2825)
                     /gene="cbpE"
                     /locus_tag="VU722_001583"
                     /gene_synonym="pce"
     CDS             complement(945..2825)
                     /gene="cbpE"
                     /locus_tag="VU722_001583"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU1772519.1"
                     /translation="MKKKLTSLVLAGAFLSLSWYGNVQAQESSGNKIHFINVHEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYKNETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGSLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYVVGWNKIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSNSEIKESNQVVKKDLENKETNQHESVASSSSSQDLTSSTSQSSEINANKSE
                     SE"
     gene            complement(2828..3715)
                     /locus_tag="VU722_001584"
     CDS             complement(2828..3715)
                     /locus_tag="VU722_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1772520.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDIPLEIVYQDEDVVVVNKPQGIVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYNLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGSRKTLKGHGQFLHAKTLGFTHPRTGKTM
                     EFTADIPEIFKETLERLRK"
     gene            complement(3705..4166)
                     /locus_tag="VU722_001585"
     CDS             complement(3705..4166)
                     /locus_tag="VU722_001585"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU1772521.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILSIAMLKEEINGN"
     gene            complement(4163..5071)
                     /locus_tag="VU722_001586"
     CDS             complement(4163..5071)
                     /locus_tag="VU722_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU1772522.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            5064..5261
                     /locus_tag="VU722_001587"
                     /pseudo
     CDS             5064..5261
                     /locus_tag="VU722_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(5313..5984)
                     /locus_tag="VU722_001588"
     CDS             complement(5313..5984)
                     /locus_tag="VU722_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772523.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(6038..6259)
                     /locus_tag="VU722_001589"
     CDS             complement(6038..6259)
                     /locus_tag="VU722_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU1772524.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            6531..7340
                     /locus_tag="VU722_001590"
     CDS             6531..7340
                     /locus_tag="VU722_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1772525.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(7521..8396)
                     /gene="aguB"
                     /locus_tag="VU722_001591"
     CDS             complement(7521..8396)
                     /gene="aguB"
                     /locus_tag="VU722_001591"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU1772526.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8406..9491)
                     /gene="aguA"
                     /locus_tag="VU722_001592"
     CDS             complement(8406..9491)
                     /gene="aguA"
                     /locus_tag="VU722_001592"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU1772527.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVTDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(9488..10615)
                     /gene="nspC"
                     /locus_tag="VU722_001593"
     CDS             complement(9488..10615)
                     /gene="nspC"
                     /locus_tag="VU722_001593"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU1772528.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEITDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(10615..11874)
                     /locus_tag="VU722_001594"
     CDS             complement(10615..11874)
                     /locus_tag="VU722_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU1772529.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGQWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQDIVPIQFLKALLPAPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(11871..12731)
                     /gene="speE"
                     /locus_tag="VU722_001595"
     CDS             complement(11871..12731)
                     /gene="speE"
                     /locus_tag="VU722_001595"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU1772530.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMTVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GYTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQTFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTKYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(12732..14192)
                     /locus_tag="VU722_001596"
     CDS             complement(12732..14192)
                     /locus_tag="VU722_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU1772531.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILS
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENVRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADIAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDFLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKEN"
     gene            14900..15595
                     /locus_tag="VU722_001597"
     CDS             14900..15595
                     /locus_tag="VU722_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU1772532.1"
                     /translation="MSETNHEIDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASAT
                     SNIWIIFLSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDMELAKKSL
                     YAAYIQNGECETSAQLLTNKAFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFL
                     GSLPPMLSITIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTKTAMIRNLAIGLLT
                     MGVTFLLGQLFSI"
     gene            complement(15926..17914)
                     /locus_tag="VU722_001598"
     CDS             complement(15926..17914)
                     /locus_tag="VU722_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772533.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTSDYNYLVVPNLQAFLDQFPDSAIYNQFYGGMNVSISEEEQLKVAEEYEKYLDQF
                     NAQLNTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQILTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     IDTTMMLIVTLSICAIFLIVYVLIFMITSRSYRKIVQM"
     gene            complement(17916..18674)
                     /locus_tag="VU722_001599"
     CDS             complement(17916..18674)
                     /locus_tag="VU722_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772534.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPTRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            19102..19293
                     /locus_tag="VU722_001600"
     CDS             19102..19293
                     /locus_tag="VU722_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772535.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(19647..19919)
                     /locus_tag="VU722_001601"
     CDS             complement(19647..19919)
                     /locus_tag="VU722_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU1772536.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(19978..20427)
                     /locus_tag="VU722_001602"
     CDS             complement(19978..20427)
                     /locus_tag="VU722_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU1772537.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(20414..22543)
                     /locus_tag="VU722_001603"
     CDS             complement(20414..22543)
                     /locus_tag="VU722_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU1772538.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEVVLAKIQEQGKLTKELEEAILEAEKLADVEELY
                     LPYKEKRRTKANIAREAGLFPLARLILQNVADLEQEAEKFVCEGFATGKEALSGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYDFSETVGNMQGYRT
                     LALNRGEKLGVLKVDFEHATDRILAFFAARFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASSESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         6702 a         4960 c         4155 g         6817 t
ORIGIN      
        1 taaacatgat ttttcttgtc ttcctgagat tatggcttgg gatgagtatg cttttacaaa
       61 gggaaagatg agcttcattg cgcaagattt taacaatctc aatatcatca ctgttcttga
      121 gggtagaaca caagctatca ttcgaaatca ctttcttcgc tacgatagag ctgtccgatg
      181 tcgcgtcaaa attattacta tggatatgtt tagtccttac tatgacttgg ctaaacagct
      241 tcgctttcaa atttctaggc tcaggctgaa acagtctccc aaactgtttc actcccgaat
      301 gctaaaatcg ttcttgatcg ctttcacatt gtacaacatc ttagccgtgc tatgagtcgt
      361 gtgcgtgttc aaatcatgaa tcaattggat cgaaagtctc atgaatacaa ggctatcaag
      421 cgctactgga agctcataca acaggatagt cgtaaactca gcgataaaca tttttatcgc
      481 cctacttttc gtatgcattt aaccaataaa gagattttag acaagctttt gagctattca
      541 caagacttga aacatcacta tcagctctat caactcttgc tgtttcactt tcagaataag
      601 gaaccggaga aatttttcgg actcattgag gacaatctaa agcaggttca tcctcttttt
      661 cagactgtct ttaaaacctt tctaaaggac aaagagaaaa tcgtcaacgc ccttcaacta
      721 ccctattcaa acgccaaatt ggaagcgacc aataatctca tcaaacttat caagcgcaat
      781 gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga tttttatcgc ccttaatatc
      841 aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc tgacttcaac ccactacagt
      901 tgacaaagag ccgaaaaaga aggccctaaa accttctttt actactattc tgattccgat
      961 ttgtttgcat ttatttcaga gctttgtgaa gttgatgaag ttaaatcttg actagatgaa
     1021 gaacttgcaa cactttcatg ttgattcgtt tctttatttt caagatcttt tttcactact
     1081 tgattggatt cttttatttc tgaattactt gtagttttaa ttgtagcaga tttctcgatc
     1141 ggaacatcca ctaaccaggc accacttgaa tccacagtat agccttctgg tgtcttacca
     1201 ttcacaagta attgaccatt ttctttcaag aagtaccatt tatccttgtc tttaatccaa
     1261 cctatagctc gtgaaccatc tgtcttgtag aaataccaat catttgcctt tttaagccag
     1321 ccttgcttca tagctcctga ttcttctaga tagtaatgat gtccagcaac ttctatctca
     1381 cctgtcttca tgataccagt agaatccata tagtaccagg cttctttatc ttttacccag
     1441 cccgttttca tttcccctga tggagcaaag taataccatt gccccttata ttgaagccaa
     1501 cctgtcttca tagagccatc aacatccaaa taataccact gctctttatc ttgaatccaa
     1561 ccaatttcca tctggttttc tttgttaaaa taataccaga ttccatcaat tttcttccaa
     1621 tttttagcag aagcaccaga gtctgtcaaa tagaaccaat gattgttcca ttttttccat
     1681 tgattctgta acaagatacc cgtttggtta aagtaatacc attcaccttc gattttattc
     1741 caaccgacaa catactctcc tgtagaatca ggcgcttgat accaccagtt cccatatgca
     1801 ctcttatgcc aaccagcttg aaaacttgga atcggcttgt aggatgttga aatattgaca
     1861 aaaccgtctt ttcgaatatc aaaaactgtc gcatcatagt ctttgctggc tgcgttaatt
     1921 ctctcaattc ctcgttcttt gagccaatta acatactcac tatcaacacc atttttccaa
     1981 ggtagactat ccgaagtttg aacaatcaaa ctcggactca aatttttaat aaaatccttg
     2041 gtatttgatt tgttggtatc atggtgatga ttaaacttca tcaaatcaac ttttccaatg
     2101 agagaaccat acttgtcttc tgctccatga acattatcta agtcgccccc aaggtaaatt
     2161 ttcttgccat tgactttcac cacgctaatc aaggaattgg aattgtcatc ccaaattttc
     2221 tttaattcac ccgatgaatc agtttcattt ttataattat agagctgaat atccatgtcc
     2281 ccaaactgaa aatgagcatc cccttgtgtg atattttgaa taactgaaac acctttttct
     2341 gcagcagtct gtaaaacctt atcatagcca tacagattat cccatagacg ttcagaatta
     2401 gtaatacgac tatcactata tttcttaaga tagactcggt caactggata ggtagacagt
     2461 aattcatcaa catttccaat atgatcactg tgggtatggg tcaccaaaat aaaatcaagt
     2521 ttttggacac ccaattcctt caaacgacga aagacacggt ctgtcagaac atgcttataa
     2581 gtggtattga taccctgtct ccatggataa cgagaatcac ttccatctgg gaaatcataa
     2641 tcttctcctg tatccaccat ggcaaaatgt ccattgcttt caagaataat cgcatcacta
     2701 ccaccttcat gaacatttat aaagtggatt ttatttcctg aactttcttg agcttgaaca
     2761 ttcccatacc atgataaact taaaaaagcg cctgcaagta ctaaactagt taatttcttt
     2821 ttcattctta cttcctcaat ctctccaagg tttccttaaa aatctctggg atatctgctg
     2881 taaattccat ggtcttacct gttctcggat gagtaaaccc taaagtctta gcatgaagaa
     2941 attgtccatg tcctttcaga gtctttcgag aaccatagac ttcatcccca gcgactggat
     3001 gaccgatgta agccatgtgg acacgaatct gatgagtgcg ccctgtctcc agttgcaatt
     3061 ccactaagtt ataatcgcca aagcgttcca agacgtgaaa acgcgtcact gcaggtttcc
     3121 ctttagcagt tacagcctgt ttcttacggt ctttttcact ccggccaatc ggcgcttcaa
     3181 ttacaccacg atcattaggc agatttccat gaacaatcgc ccaatatttg cggagagact
     3241 ttttatcctt gagttcttgg gcaagtgcta gatgcgcatc atcgttttta gcaatcatga
     3301 gaagacctga cgtatcctta tcaatacggt gaacaattcc tggacgcaga accccattga
     3361 tacccgacaa gtccttaata tgatacatga gggcatttac tagggtccca ctggtatgac
     3421 cagcactcgg atgcacaact atcccctgag gtttgttaac gacaaccaca tcctcatctt
     3481 ggtagactat ttctagcgga atatcctcag ccacatactc taatacctct ggttctggca
     3541 catggtaagt gacgacatca ccctcttgga ctgtgtattt agctttcttg acttgaccat
     3601 tgaccaagac ctggcctgat ttaatttgtt cattcgcaag actgcgtgat aattctgtca
     3661 aatctgataa agccttatcc aaacgcagac caccagtttc aattttaatt tccatttatt
     3721 tcctctttta gcattgcaat cgataaaata atcactccaa ccgtcagata gctatctgcc
     3781 acattgaaaa ttgcaaagtt gataaagtca aggtggaaca tatccacaac aaagccctga
     3841 ctgaccctat caataaagtt tccaagacca cccgcgatta tcagagtcaa acccaagacc
     3901 atccagaatg agtcctccat gtgtttatgt aaataccaaa tggcacctat cacgacaacc
     3961 agagtaatga cagcgaataa caactgctga tcttgtaaga tagaaaaggc tgcacctcga
     4021 ttttgcaggt aggtcaagct aacgaaattg ggaatccagg agcgcacttc acccagtgga
     4081 atctgctgga cgatatagga tttgaccaac tgatccagcc caatcaaaag cagtacaatg
     4141 actgccacta ttgctctttt tttcatgatt tcctcttttg atcaaaatat tcttgcatga
     4201 cttctacgaa gagagtccca gcttgactaa gctccacttc ttcgcgttta acatagacca
     4261 tgcggttatc taggttatcc ttgagacgaa taactgtaat gccattaaca ctgtcactat
     4321 ctaaaaatcc agaacctgtc gcataggcgt ccgtccgttc caaaatacca ttcaaagtgg
     4381 cacggtctgt cacattaaac atctgtgagc ttgcactggt atcgacaaag ttctctgaat
     4441 aataaaggta ctcgtctttc tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct
     4501 ccatgactaa ttcctctttc tgggctaaag gatgaccctc acggagataa atatgggtat
     4561 ggaaaggaat caattcgatg acctccagac ctaatttttc aacccgttgc ataatcccct
     4621 ttttattttg attgttgagg tagataatcc caatctcact atgcccttgc gccacttcat
     4681 ctaatatttg aacagtagtt gattcaaaaa tacggaagtt cttatagtca ggatagcgct
     4741 ctgaaaaggc cgtaatagtt ggtggcaaga agtcatagtg ctggctagca acggaaaatt
     4801 catctttttc ttcttcagga ttggcatact gattttgaaa aatatcaaat cctttaacca
     4861 attcttgcgc tttttcataa aattccatcc cacgacgggt caagaaagtc cctgagctgg
     4921 tccgacggaa aatcttaaaa cccaactctt tttccaaatc acgaacagaa atagacagac
     4981 tcggctgact aacatacatc ttttcagcag cttcacggaa agtaccacta ttggcaatgg
     5041 ccacaacata gcgtaattgt tgaatgttca tcttctaccc ctaacttctt tatcttttca
     5101 ttataccata ttttagaagt tttccaaaaa ggaaaaaaga acatcctatt cttcttaact
     5161 atcttcacta tctgcctttc tcaagccaac cttattttca aaatcaattc aaaaaaataa
     5221 ctggatacac accactacaa tatcgaaaag aaaaacgttg actatttgtg aaaaaagaaa
     5281 atgccggaaa gttccgacat tattttagta agctaacttc ctgaaaatag gagcaaccac
     5341 acatcccaga aggcagtgat attaatgaga atatgaacta gtattggata gtagagattt
     5401 ttagtcatgc gatacaatag agctaaaata agacctccac tagcataaat gaaaaaagca
     5461 agaggagtta aagcaaaatt gatatgaata taaccgaaaa taatagcaga aagcaagaca
     5521 tctccgtacc aaggcgagtt tttgaaaaag gttgtcataa gcacaccgcg ataaatcaat
     5581 tcctcagcaa tagggccgat gaagcaaacg atgagcaaaa aatagggtaa ttcctgtctc
     5641 cctatcattt ctatcgtttc attcaaagaa atttgatttg aagacagaga tatgaaatac
     5701 gaaaagagaa agtcagacat atacgaagtg atgtaaccca gtaaaaggta gataaaatac
     5761 ctcagctgcc acttgaaatg aaaagttttc tttcctgcaa aaactagtag atagatgacc
     5821 gctaataaaa gaactccact ctccatcaaa agcagaatct gaaaaaattc acgacttgct
     5881 ggtagatagg gctttgcgag ataattgaaa agcctccaaa accaagttga tttgtaaaaa
     5941 attaaggaca atactagtaa aatttgaata gctcgttttt tcatattaaa tcctctgttt
     6001 tctccccttg tttcttcata ttcctaataa attttactta aaatctcgca gcacttcctt
     6061 tgcaaagatg attgcctcct ccaatatatc ctaaatcata ggtgcctctg ggacaaaatc
     6121 catgaaccgg cagagttaat actggttcta tttcccaatc gtacctacca ttaggatttt
     6181 taccataggg atctgctcca ccttgtatca gctctaattc ttcatttgtt agatttatat
     6241 tttttgtcat taaaatcatg atatatttcc tccattattc ttcagattag ttgagtaatc
     6301 tgatactcat acctacttac aaaaaaacta ttatattaag ttggtttttt aatttgtcta
     6361 gttgcaacat tgacaaacat agcatagcat atctttgcga aatatcctct tcaaatcatg
     6421 aattgtcatc aaaacatctt aaactataaa atcaattagt ctcaagcttt ctatcaattt
     6481 cttctccaaa atatgctata ataatagcaa aagataaaga aggaagacct atgattaaac
     6541 tactagcctt ggatatggac ggcaccctcc tcaatgaagc caaggaaatc ccacaagctc
     6601 acattactgc tattcacaaa gccattgaaa aaggtgtcaa actggttctc tgtacgggtc
     6661 gccccctttt cggtgtcctc ccctactaca aaaaactgga gcttgacctc cagaacgaat
     6721 atattattgt taacaacggt tgttcaactc accagactag cgactggggc ttggttgact
     6781 ggcaagaact gagtccagct gacatcgaat acctctatga ccttgctgaa aagagtgatg
     6841 ttcagttgac actttttgac gagtcacatt attttgttct cggtggcaaa cccaatcaag
     6901 ttattgaaaa tgatgctaaa ctagtatttt cagacctgac tgaaatttct cttgaagaag
     6961 cgactagtgg aaagttccgg atgttccaag gtatgttttt aggaacaaaa gaacaaacag
     7021 acgattttga gcagcgtttt gctgaagagc tttgccaacg attcagtgga gttcgttcgc
     7081 agcctgtcat ttatgaagca atgccgcttg gaacgacaaa ggctactgct ctttcacgac
     7141 tagctgagat tttgaagatt gattcctcag agattatggc catgggcgat gctaataacg
     7201 atatcgaaat gctccagttt gcagggcttg ggattgcaat gggaaatgcc agcgattatg
     7261 tcaaatctct tgcggatgcc gttacatcaa gcaacgaaga agacggcgtt gcgcgtgcta
     7321 ttgagaaata tattctataa aaaagaaaag caaatagaca gaagttactg ctatttgctt
     7381 ttttgctaat attttaaaat acggactaat caatagacaa gaatagcgaa tcataaaaat
     7441 cgatttacta gatgccatag tatcttatag ttgctaataa gaagttagtc tagcagaatg
     7501 aatctctcat ttctcccaca ctaatctgta atttgtctat acatttctgg tcttctatct
     7561 cgaaacaagc cccagtttag gcgttcactt gctcccttgt ctaggtcata agtagctaac
     7621 agaacagctt cttcttgtct ttcagctcgt tctagaatag ctcctgtttc atccgtcata
     7681 aaggaggaac cgtagaagtc aagactggaa ctctgtccgc cattttcctc actaggagta
     7741 acctcctcta aaccataacg attggctgcg atgactggaa caatattcgc tgctgcgtgc
     7801 ccttgcatag tacgttgcca gtgaccacaa ctatctgtat ccaaaattgg ctctgaaccg
     7861 atagctgtag gataaaagag caattcagca ccattcaatg caagacagcg cgctgtttca
     7921 gggaaccatt gatcccaaca gataccgata ccaatcttag catagcgagt attccagacc
     7981 ttgaaaccag tgttaccagg cgtgaaatag aatttttctt gataataatg gtcatctggt
     8041 atatgggtct ttcgataaac gcccagcact tccccatctg catcaatgac ggcaatagag
     8101 ttatacaaga cattaccatc tttttcatag aaactgattg gtaaaacaac ttgtagttcc
     8161 ttagcaatca ccttaaaatg ctgaatggca gtattttccg ctacagattg ggcatactgg
     8221 tagtagtcat actgacgttc ctgacagaaa tagggatgtt caaacaactc gggcaagaga
     8281 ataatttggg ctccttgctc agcagcctga cgtactaaac gctctgcggt ttggatattt
     8341 gttgccacat ccttagcgca ttgcatctga atggttgcaa ctcttacatt tctcatcttt
     8401 ttctcctatt ctggaatttg ttgggtgata cagtggatat tgccaccacc taagagaata
     8461 tctctggctg gtattccgac aactttacgg tctgggaaac acttgctgag gatatctaag
     8521 gccacttggt cgtttacatc ctcaaactgt ggaaccaaga cagccttgtt ggcgatataa
     8581 aagtttacgt aggaagctgc tagtcgttca cctgcgtatc gcttttcttc tccttcttca
     8641 tagatgtagc ctggcaaatc ttcttctgtc acaacttgtc gaactgcagg gataggcaat
     8701 ttatgaatgg tgaagtgaca accttttgca tctgtttcct gttctaagag ttcgagatct
     8761 gcttttgaca tggcatactg gggatcattt tcgtcatctg tccaagccaa aacaagctca
     8821 gcaggaccaa caaaggcagc aacattatcg acgtgttcat tggtttcatc ctgataaata
     8881 ccataaggaa gccaaataac tttttcagca ccaagacttt ctaataatgt gttttcaatc
     8941 tcctctttag tcaggttagg attgcgacca ggactaagca agcaactttc agttacgaga
     9001 atagttcctt gaccatcgct atggattgcg cctccttcca gtacaaaagg tttagcatca
     9061 tagacaggcc tttccaaggc ctcagcaaaa cgactggcta cttggtcatc ctcttcataa
     9121 tcttgataaa gaccatcata ggtgcctccc caagcattaa aggcccaatc cacggctaat
     9181 ttcttacctt tatcagtgac gagaatggtt gggccagtat cacgcgccca ggcatcattg
     9241 gtgggaatgt ctaaataaac aaccttgtct ccaagatagg attgggcttc agatagatag
     9301 gcctgctcca ccaaaagata gactctttcc ccttctgcta tggtctcgat gatctgagta
     9361 aatgctcttt tagcagcctt tccttgaaaa ggccatgatc ctggtcgagt cggccatatc
     9421 atgagggtac catgatgggg ttcgtactct gctggcatgt gatagcctaa tttttttgga
     9481 ctgtccatca tgataatctc cctttaaagt cttgatagcc aaaagctttg agtaagctac
     9541 agtctccctg ttcgtccatg agatagagac ttggcaatcc aataccatta aaggtattat
     9601 ttttgacaaa agaataaatg gccatgtctt gaaaataaag tctgtctccg atttggactg
     9661 gattttcaaa actataatca ccaatcacat cgcccgtcag acaggtatta gaagaaagtc
     9721 tgtaggtatg ggctttttcc tgtgcctcaa agccatttct caaaggtgga cgatagggca
     9781 tctcaagtac atcaggcata tggcaggtcg cagaggcgtc taaaaccaag atttccatac
     9841 cgttttctac aatatctaat acctcagttg ctaaataacc cgcattaagc gcaatggctt
     9901 caccaggctc gatatagatt tcaagattgt aagtttttcg gatacgcttg atttctgaaa
     9961 tcagcaaatc cacatcgtaa ccttctcttg taatatgatg accaccaccc atattgagcc
    10021 attttacctc atgtaagtag ggaccaaact gttcttctac tgctttcaaa gttgtttgta
    10081 aatcatctgc tccctgctcg caaagggtat gaaaatgaag tccgtcaacc aaatccagca
    10141 aatcactcgg aatcttgtct atagtaactc caaagcgaga acctggtgca caagggtcat
    10201 agagcgcgtg atctccttga gttgaacact gagggttgag gcgcaaacca acactgacac
    10261 cagcctctcg acaacgcgga ccgtgtttac gcaactgtct ctctgagtta aagacgatat
    10321 ggtccgttat ctctagcaat tcctccaagt ctgcatcctt gaaagcaggc gcaaatacat
    10381 ggacttcacc aggaaattct tcccttgcca atttggcctc atagagtcca ctagctgtcg
    10441 tacctgatag atactggcta atcaagggat aagttttgta gagggaatat gccttctggg
    10501 caagcaagac cttgcaaccg gcctcttctt gtacatattg tagaatgcgg caattagctt
    10561 ctaacttggc caagtcaata acataggctg gtgttggtac ttgttctaac ttcattagtc
    10621 caccatttgt ggattttcaa ccacaaccca tggcaaacca tactcattca aagcttccat
    10681 gaatggatct ggatctaact cctcaaggtt atacactcca gcttgtttcc aagttccgtt
    10741 catgactaat tttgtcccaa tcatggctgg aactcctgtc gtgtatgaaa ttgcttgtga
    10801 cccgacttct gcatagcact cttgatggtc gcaaacattg tagatgtaga tagtcttttc
    10861 aacgccatct ttgacacctg taaagataca tccaatattg gtttttccga ctgtacgtgg
    10921 cccaagactg gcaggggctg gaagcaaggc ttttaagaat tgaatcggaa cgatgtcttg
    10981 tccattgaag ttaatggtat ccgtacgaag gagtcctaca ttttcaagac atttcatatg
    11041 tgtcaagtaa gattgaccaa aagtcataaa gaaacgaatg cgtttgactc caggaatgtt
    11101 cttggccagc gattcaattt cttcatggtg aaggagatac atatcttttt gtccaacttg
    11161 agggaaatcg tactcacgtt tgatagacat agcttcgact tcgacccatt gtccatcttc
    11221 ccaataagaa cctggcgcag aaacctcacg gagattaatt tctgggttga agttggttgc
    11281 aaatggataa ccgtggtcac cgccattaca gtctaaaatg tcgatataat ggatttcatc
    11341 aaaatagtgt ttgagggcat aagctgaaaa gacactagtt acacctgggt caaaaccaga
    11401 accaagaaga gcagtcaagc ctgcttcttt gaatttctct tgataagccc actgccatga
    11461 gtagtcaaag taggctgtaa aaccaagttc cttacaacgt ttttcgtaga tagcacgcca
    11521 ctcagggtct tctgtgtctt ctgcttcgta gttggctgta tcgatatagt gaacacctgt
    11581 tgccaaacaa gcatccataa tggttaaatc ttgataaggc agagctacat tcaaaacagc
    11641 ttctggtttg tagctttcaa tcagggcaat cacttcttca accttgtcag catcaagagc
    11701 agctgtctca atctttgtac ttgttttgcc ttccagttta gctttcaagt catcacattt
    11761 tgacttggta cggctagcaa tcataatctc tgtaaatgtt tcgctatctt gacaaatctt
    11821 cgaaatagca acttgggcaa cgcccccaca accaataact agtaaacgac tcattttttt
    11881 ccttcctctt cttctaaaat gtcttctaca tacttgggca acataaaggc tcctacatgt
    11941 aagtttgcag tgtagtattt tgtgaaaagc tggcgttttt tccagccttc cttgtcaaaa
    12001 tctttgacag gatggtattt tttcgatgca aatccaaata accaatagcc cgccggactg
    12061 gtagggatat gggcttggta gacacgacta attggaaagg tctgattgac ctttcggtgc
    12121 atgcttcggc aagccgactc atcctcatca aagaagggac tcccatgctg gtaaatcata
    12181 atgccgtctt ccttcagagc tcgataacta ttaccgtaga attccttagt aaagagccct
    12241 tccgtatagc caaagggatc tgtcgcatcg ttgatgataa tatcataatc atcttcgcag
    12301 tttcgcaaaa aacgtagccc attttgataa taaatggtaa cacgtggatc atctagccct
    12361 gcagcaaagt ctggaaaata ctcacgacaa acctcaacca acatttcatc aggttctaca
    12421 atatcgattt gttccaattc tggataaagt gttaatactt gagcaacacc accgtcacca
    12481 cccccaataa ccaagacttt cttgggattt gggtggacag tcatgggaac atgaacggtc
    12541 atttcattgt agacaaagtc atccgcatct gaaaataaga cgtgcccatt taaaatcagt
    12601 attttcccaa aagctggtgt atccaagact tcgatatctt gccattcact ttttccagcg
    12661 tagagttgct tggctgttct cagggacaat tttacatctg gagtatgaac ttcagaaaac
    12721 cataaatcca tctagttctc ctttctctta atgacgttga tgtgattgac ctcaggatct
    12781 tccgtccctt ggagggaaca accacgttcc ttggcaaatt ggatatagtc tacaatttct
    12841 cgtgtaatgc gttcaccagg agccaagata ggaatccctg gaggatagca catgacaaat
    12901 tctccacaga cttgtccaac agattcgtcc aaggttaaac tttttctctc tgaatagaag
    12961 gcttcctgag gagataacac caactcgggc tgaatatatt ctcctgctat caagtccttc
    13021 ccatctcgtg aatagagtct ctttatgtca gccaaagcac cgaccaagcg ctcgatgtct
    13081 tggatgcggt caccaatcga aatataggcc aagatattgc caatatcacc aaactcaatc
    13141 tgaatgtcgt attcgtctcg taggaagtca taaacctcga tacctgttaa gccaataccc
    13201 tgagtgtaaa ctgacagctt ggttacatca aaatcacaga ccgacacacc atctattaac
    13261 tcttttgagt aggcatagta tccaccaata gcattgattt cacgacgagc gtactcggat
    13321 agctcaatga ccttctcaaa cgactcttta ccacgaaggg ccaagttgcg acgtgaaata
    13381 tccaaactag ccatcaacag gtaagaagca gatgttgatt gggtcaggtt gatgatctga
    13441 cgaacgtact cgggattcat ctgctctccg attaaaagaa gcgaactttg tgtcaaactc
    13501 ccaccagact tatgcatgga gactgctgct atatcagcac ctgcatccat agcagaaatt
    13561 ggaagtttat ctgtaaaatg caaatgcgct ccgtgggctt catctactaa aaccatcata
    13621 ccagcttcat gagccatttc tgtcaacccc tttaggtctg aacagattcc gtagtaagta
    13681 ggattgttaa tcaaaatggc cttggcatct ggatggtctt ttatggcctg tgctactcga
    13741 acattttcaa gacctaaagc gataccaatc ttaggatcca cactcatctc gatatagatg
    13801 ggaatggcac cacatagaac cagcgcattg atagcagatt tatggacatt tcgtggcaga
    13861 ataatcttat ctcctgcctt acaggttgac agaatcatag tctgcaccga tgaggttgtt
    13921 ccccctatca ttagaaaagc atggctagct ccaaaagcat ctgcagccag ctcctctgca
    13981 tcacgaataa tcgaaatagg atggcctaaa ttatccaagg gtttcatcga attgacatca
    14041 atgcctacac atttttctcc taagagttcg acaagttctg gatttcctcg tccacgcttg
    14101 tgacctggaa catcaaaggg aacaatcctt ttcttgcgta acttcaccaa ggcctcataa
    14161 attggggctt ggttttgatc taactccttc aagacatact cctttcaata tttttaggac
    14221 cttatgaaaa ctaaggaact aaaggttgac tcatgaaaaa agagcaggtt ttcacctgct
    14281 ctgcaatctt ctgacgtgtt tattttggtt tctgttgagt atgtctgttc ccgatgtttc
    14341 ctaactctct agtagcaaat attacgtact ttattgatcg tttcacaaga tgacgtgtgc
    14401 tttcaccaca ctaaaaattt atgaattagg acaagtgtcc taacatcaac ttataaaagt
    14461 aggcttttaa ccctatcaat aatgtggctt ttcaaccacg cttcggcatt caaccctgcc
    14521 tgtccgtagg cattttttac tcgggtttat atttgctaga aaacatcatc tcattttcta
    14581 agctttatta ctatatcatg tttttaagaa cttgtaaagc ggtttacgaa aaaaatataa
    14641 aaaagttcgc aaaatatttg gattttattt gatttaatac tacttatttt attgtaaacg
    14701 attataaagt gaacaaaatg tttatcgtat ttaatttaaa atttttatgc tattctatac
    14761 tctttacctt cggtgtttga tctatcagaa aagatgtcga catttttata tcattaaaat
    14821 cgtgcaactt ttttcagata cttttaaaag attgatttcc ctatattttt cctttatact
    14881 ggataaaaag gagattagta tgtcagaaac aaatcacgaa atcgattcaa attttgcagg
    14941 tcgtttaaat atcctgcgtg cgggtgttct tggtgctaat gatgggatta tttccattgc
    15001 tggtgtggtt attggggttg ccagtgctac aagcaatatc tggattatct ttttgtcagg
    15061 ttttgcggct atcttagctg gtgccttttc aatggcaggt ggagaatatg tatccgtttc
    15121 aactccaaaa gataccgagg aagctgccgt ttcgcgagaa aaactcttgc tagaccaaga
    15181 tatggaacta gccaaaaaat ctctctatgc agcctatatc caaaatggag aatgcgaaac
    15241 ctctgcccaa ctcttgacca acaaggcctt tcttaaaaat ccactcaagg ctctggtaga
    15301 agaaaaatat gggattgagt atgaagaatt tactaatcct tggcacgctg ctatttctag
    15361 cttcgttgcc tttttccttg gtagcttacc accaatgctt tcaattacca ttttcccaag
    15421 tgaataccgc atccctgcta ctgtccttat cgtcggtgtg gcccttcttc tcactggtta
    15481 cactagtgcc agacttggaa aggatccaac caaaacagct atgattcgga acctagctat
    15541 tggtctcttg accatgggag ttaccttttt gctaggacaa cttttcagca tttaatactc
    15601 ttcgaaaatc aaattcaaac cacgtcagct tcgccttgcc gtatatatgg ttactgactt
    15661 cgtcagtttt atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttttatctg
    15721 caacctcaaa acagtgtttt gagctgactt cgtcagttct atctgcaacc tcaaagcagt
    15781 gctttgagct gacttcgtca gttctatctg caacctcaaa gcagtgcttt gagcaacctg
    15841 cggctagctt cctagtttac tttttgattt tcattgagta taaaatacaa gaaatacctc
    15901 gattttgaag tcgaggtatc tttttttaca tttgtacaat cttgcgatag cttcttgaag
    15961 taatcatgaa aatcagcaca tagacgatga ggaagatagc gcagatagac aaggtcacaa
    16021 tcaacatcat agtcgtatct attacaccaa tcacttttaa aatcagacta agcatatggt
    16081 aggcaaaggc taaatgtatg aaggcaaaga gcaaaggaag gaagaaaact gttaaaatct
    16141 gtttgttgat ggtttgcttg atttgctttt gatctaaacc aactttctgc aagataataa
    16201 agcgctcacg gtcttcatag ccttcagaaa tttgtttgta gtaaatgacc agaacggttc
    16261 cgaccataaa gataatggat aggaaaatac cgataaagaa gacaccacca aagagggcac
    16321 tcatctgagc actagcatct gctagagtgc taccataaac atagctacct tccgtgttta
    16381 attgagcatt aaattgatcg aggtattttt catattcttc agcgactttg agttgctctt
    16441 cttcactgat acttacattc ataccgccgt aaaactgatt atagatagcc gaatctggga
    16501 attggtccaa aaaggcttgt aaattaggta caacaaggta attgtaatca gaagtcaaaa
    16561 tattaaactg atttggaaca tggtttacaa tgaaatcttt agtaaattct tcttttacag
    16621 aaaattgatg atcatttaga gttagagctt tctgttcttt aactccctca ttctttgcaa
    16681 agagtccgac ctcatttcct gatagagaca gtttttgacc agtcatattt tcataatctt
    16741 tttggtcaaa taccatgaaa actgttttgg gttggacacg gttttgtcct ttttcaaaaa
    16801 tagttaactt ggttccttct tgatttgcaa taccaaagtt actgtaacga agtacttctt
    16861 tctctttgac actataacct ttgtcacttg caaactggct caagagtttg tccaaatctt
    16921 ctttttcaac attttgccct gaaaccccaa aatcatgagg atttagaact tttttaaagc
    16981 tttctgcgga attgaaaatg cttgtcgctg ctgacatggt taccaaaacc attgttgaca
    17041 aaatagcgat ggttgctagt ccaaccgcat ttttcttcat acggaaaatc aagttggaaa
    17101 cagatatgag gttattaggt tggtaatagt atttcttgtt tttctttaag atttgtagga
    17161 agactgtaat ccctgcatta aacaatagat aagtaccaaa gataaccagc aaaacagcta
    17221 ggaagaaagt tgttagggct gtaagaggat cggttaccgt aagggcaaga taatagccaa
    17281 tccctaaact tatggaacca agaatcgttt ggagaggaag gaagcgacct tttttctctc
    17341 cgctagcttt ctcacgtgag agctggaggg cattcatacg ggcgattcga agggcattca
    17401 ggaacatgag gcctaggaaa atcaaaccga agacaagaag tactgtaatg acaactttca
    17461 tctggaaggt agcgaccagt tccaccttca atttcatcag tttgagtagg aaagcgaaaa
    17521 tcaacttgtc aaacaaggct ccaataccga ttcctgctcc aacagttaga atcccaaata
    17581 gcactaactc cttaaaggtc atactgatta gatggcgctt ctccaagcct aacatgccat
    17641 atatacccag ttccttggaa cggtttttca tgacaaaact attggcatag aggacgataa
    17701 tggctgacgc aagggtaacg acaaacatac caaatccaag tgttgcttga atggtggttc
    17761 ctccacggat ttccgcaatc tttggattga aggttaggga gtaaaagaga taggtgatgg
    17821 tgactgccaa gagaacagcc agtgcaaagg gatagtagag tttgcggttt ttaatcaagt
    17881 tcgataccgc taacttattg gttaatcgaa acatactaat tcacctcgct tgccatgaca
    17941 gtcaaggtat cagagatttc ttggaacatc tgacgctctg tcttctctcc acggtagatt
    18001 tggttgtaaa gaatgccgtc cttgataaag agaacacgct tggccctgct agcagctgct
    18061 gttgagtggg ttaccatgag gatggtttgc ccacgctcat tgatttcatt aaagacatca
    18121 agtaaggctg cagatgactt ggaatcaagg gctcctgttg gctcgtccgc aaggagaatt
    18181 tcaggttctg tgatgatggc gcgggctact gctacacgct gtttctgacc accagaaatc
    18241 tcgtaagggt acttctcttg caattggtta atacccagat tctcagctgt caccaccaat
    18301 ttcttcatca tctccgttat aggtcttctt gacaagacaa gcggaagcaa gatattgtcc
    18361 ttaacagaca gagtatctag caagttaaag tcttggaaga caaatcctag cttttcacgc
    18421 cggaaactag aagcctgtga atttttaata gttgcggtgt cagttccatt caagtaaacc
    18481 tgcccacgag ttggtttatc caacatagct agaatattga gaagagttga tttaccagaa
    18541 ccagactcac ccatgatggc aacgtagtca cccttttcta cggtaaagtg aatatccttg
    18601 agggcctcta cttggttgcc ctgaaaacgt gttttataaa ttttttgaac gtgttttaca
    18661 tctaaaagtg tcatgagaat ctcctttctt aatatcccat caaatgaaat gtagcttgca
    18721 tcatagtgca tcccagctga acgcgctcaa tttctttgtg acttggtttt ctagttttct
    18781 tatgtaagat ttgtttcatg atgttactcc tttgttcttt atgagtctag tttacatcaa
    18841 aaaaagaccg cttgccataa cctaacctta caaaagagac tttaatctta catttttgta
    18901 agattgggtg aaatataagc aaaattactt agaaaatgat ttgatttcct atttttaaag
    18961 ttgtaaaata taagtgtgaa aaagcttact ttgaaaagga ggaagcggga actaacattt
    19021 tagtaagctt acctagataa cataccattc aatttaacac ttgcaagtcg ttcaacctat
    19081 aaggaaagaa ggtgcgcttt aatgaaacac aaagaacata tactcatcgg acttctctat
    19141 ctgctctctc cattcatcgg tcagctctta gttgaacaca cacactttat cagtacagaa
    19201 tttaccggca ctgcttatgt tatttgctgg ttatcagttg ttatcagcat ccaccatttt
    19261 tccaaaaatg tattgtctca acagcaaaaa tagattaaaa aactgcgttt aaattactgc
    19321 ttttatagta aaatgaaata agaacaggac aaatcgatca ggacagtcaa atcgatttct
    19381 aacaattttt tagaagtata ggtgtcctat tctagttcca atccactata gtttgtggat
    19441 gaagctggcg aaatattatt aatactattc aaaaatcaaa gtgcaaacta tatcaacttc
    19501 acattgccga ctaaattaca gcctgcggct ggcttcctag tttgcacttt gatttttatt
    19561 gagtataaaa gtaaaaaagc tttaaatcaa gcagtttaga ctattgattt aaagcttttt
    19621 gcgtattcca aatcttttgt aaaacctcac caaaaccagc cttcattatc gtcaatggct
    19681 tgagcttctt tgcgtttacg tgggcctgtt ccgtacattt ctgcttcgat ttcttccttg
    19741 gttggcatga tagaagctag gatgatatag ataatcaccc caagtccaaa gtttgcgact
    19801 gtaaaaatgg caaacagaaa acgtacaagg gtaacatcaa agttccactt gtctgacaga
    19861 cctgctaaaa ctcctgaaat catgcgattt cgtctcattt tataaaactt actgttcatg
    19921 atatttcctc tttctgctag gttagacata gtatatcacg gataggctcg gctttcatca
    19981 gtcctcaggc tgatttacta atagcaactt tcctcgacaa agtccacagc gatagcgttt
    20041 ggtatcaatc ctacgcttac gctgataagt ttgctggcag gattggcaac gatagagctt
    20101 gattggcttg gagttactat tgggcaagga tggtacaaac cgtaatccat ccactgcttt
    20161 caacagttcc ttaaaatccc gatccttgtg ttgatagcct ttcccttgaa aatagaggtg
    20221 ataatgacag agttcatgtc ggacaatttt cctaaaaacg tccaacccca gttcctgata
    20281 aaccttggga ttaaaatcca aatgcccatc tttggggaaa aatcgcccac ctgtcgaacg
    20341 tagacgccta ttccactgga catgatggat aaaaggtctg ccgaagtctt ctagtgaaac
    20401 ctgcttgacg taatcagtca gtttcatttg gagctaggag agacagatta actttttcac
    20461 gttcagtatc aattttctta acccaaacgc tcaccaaatc tccaactgcc accacttgac
    20521 tagggtgttt gataaacttg cgactcatat gggaaatatg gatgagaccg tcctcatgaa
    20581 ttccgatatc aacaaaagca ccgaaatcaa caacgttacg caccactcct tctagctttt
    20641 gtccaaccac taagtccttg atatctagga catcttgacg gagaactgga gcatcaaagg
    20701 aatcacggaa atctcgacct ggtttgagaa gatctgcaat gatatcttta agagtttctg
    20761 gaccaaggtc taactcttgc gccatttcct tgactgaaag cgacttgagt ttgctttggg
    20821 cctcttcatt cagatcctta atgtccaagc atttgaagag ttccttaacg gcagcgtaat
    20881 tttctgggtg aactcctgta ttatcaagga tattgctact ttcagggata cggaggaaac
    20941 cagcagcctg ttcaaaagcc ttggccccca aacgaggaac tttcttgatt tgggagcgtg
    21001 aagtgatttt tccctcttcc tcacggtatt tgacgatatt ttcagaaatg gttttattga
    21061 gtccagctac gtgtgaaaga agagctgggc tagctgtatt gacattgaca ccaacttggt
    21121 taaccactgt atcgacaaca aagtccagac tctcagatag tttcttctga ctgacatcgt
    21181 gttggtattg accgacacca attgacttag gatcgatttt gaccaattcc gcaagaggat
    21241 cttgcaaacg acgggcgata gaaatggcag agcgtttttc aacggtcaag tctggaaact
    21301 cctgacgagc aagttcgctg gcagaataga cagaagcacc actttcatta acgataacat
    21361 agctgacttc agggaaatct ttcagaactt ccgctacaaa agcttcactt tcactactgg
    21421 ccgttccatt tccaatggca ataatctcta caccgtattg accaattaaa tctgctaaat
    21481 ctttcttggc ttcttcgatt tgacgagctg atgctggttt aacaggataa ataacctgag
    21541 ttgtcagcat ttttcctgtt gcatccacga cagctagctt ggcacctgta cgaaaggctg
    21601 ggtcaaaccc aagaaccacg cgccctttca gtggagcaac caagaggaga ttgcgtagat
    21661 tgtcagaaaa gagttggata gctccttctt ctgctttttc agtcaattct gtccgaatac
    21721 gacgctcgat agcaggcaag accttcttct taacagattg ctgaaccact tcatcaatat
    21781 aggcattttt taccttgaaa cgagcagcaa agaaggcaag aatacggtcc gtcgcatgtt
    21841 caaagtcgac cttcaagaca cctagcttct ccccgcgatt gagagccaag gtacgataac
    21901 cctgcatgtt cccaactgtc tcagaaaaat cataataaat ctgaaaaacc tgcttttcat
    21961 caagactttc atccttgact tgagaagtga gtttagagtg tctcagcact tcctgataag
    22021 tcatggaacg caaggtcaca tcttccgata aggcttcgac caaaatatca actgcaccag
    22081 acaaggcttc cttaccagtc gcaaatcctt cacagacaaa cttctcagcc tcttgttcta
    22141 agtcagctac attctgcaaa atcaagcgag caagtgggaa gaggccagct tcacgggcaa
    22201 tgttcgcctt ggttcgacgt ttttccttgt atggaagata gagttcttct acgtctgcta
    22261 gtttttcggc ttctaagata gcttcttcca attccttagt cagcttgcct tgttcttgaa
    22321 ttttagctaa aacaacttcc ttacggtcat ttagatttgt cagactttta tccaagtcaa
    22381 taatggcctt aatcgccacc tcatccagac taccagtcat gtccttacga taacgcgcga
    22441 taaagggaat agtcgcccct tcagctgtca aacttagaac ggtatcaatt tgctttaaag
    22501 tcactcccaa atcttgggag attttttcat attttttatc catgaatcta ttataccaca
    22561 agctggaagg ctttctccaa tccttttcat actcaataaa aatcaaaaag caaactagga
    22621 agctagccgc aggc
//
LOCUS       DAVFJR010000034        21848 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVFJR010000034 DAVFJR010000000
VERSION     DAVFJR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.035"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..97)
                     /gene="blpN"
                     /locus_tag="VU722_001604"
     CDS             complement(<1..97)
                     /gene="blpN"
                     /locus_tag="VU722_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU1772539.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCA"
     gene            complement(113..367)
                     /gene="blpM"
                     /locus_tag="VU722_001605"
     CDS             complement(113..367)
                     /gene="blpM"
                     /locus_tag="VU722_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU1772540.1"
                     /translation="MNTKMMEQFEIMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            648..2801
                     /gene="blpA"
                     /locus_tag="VU722_001606"
     CDS             648..2801
                     /gene="blpA"
                     /locus_tag="VU722_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU1772541.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYILNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMDYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVFTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2812..4173
                     /locus_tag="VU722_001607"
     CDS             2812..4173
                     /locus_tag="VU722_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU1772542.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSFVATKE
                     ITVTSQGEIAPTSAIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFRNFTKQSHDIELGISKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINKRARLPTGNPHQSILNRY
                     LVAAQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIIHLSSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHCITIIAQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4230..4385
                     /gene="blpC"
                     /locus_tag="VU722_001608"
     CDS             4230..4385
                     /gene="blpC"
                     /locus_tag="VU722_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU1772543.1"
                     /translation="MDKNQNLTSFQELTTTELNQITGGGWWKDLLHRFNVIEQNNTKG
                     FNQPIQL"
     gene            complement(4427..5767)
                     /locus_tag="VU722_001609"
     CDS             complement(4427..5767)
                     /locus_tag="VU722_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1772544.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKN
                     KLHERLNQEQTLRYRDMERHSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDSVLKDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFLKARDKKIIFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIHTE"
     gene            complement(5781..6519)
                     /locus_tag="VU722_001610"
                     /pseudo
     CDS             complement(5781..6519)
                     /locus_tag="VU722_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(6524..6862)
                     /locus_tag="VU722_001611"
     CDS             complement(6524..6862)
                     /locus_tag="VU722_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772545.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQKRILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7118..7447
                     /locus_tag="VU722_001612"
     CDS             7118..7447
                     /locus_tag="VU722_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU1772546.1"
                     /translation="MTDTDPIKRAQALITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETADNRVLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLSL
                     YGPTIIL"
     gene            complement(7508..8557)
                     /locus_tag="VU722_001613"
     CDS             complement(7508..8557)
                     /locus_tag="VU722_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772547.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLAMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQAVVRGLTSLVLVVELVVGLVTFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(8554..9285)
                     /locus_tag="VU722_001614"
     CDS             complement(8554..9285)
                     /locus_tag="VU722_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772548.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYKELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9353..9763
                     /locus_tag="VU722_001615"
     CDS             9353..9763
                     /locus_tag="VU722_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU1772549.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9773..10060
                     /locus_tag="VU722_001616"
     CDS             9773..10060
                     /locus_tag="VU722_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772550.1"
                     /translation="MKLSNLLLFAGATAGSYLVTKNRQTITDEILNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKILEKDIQTRLAVIKEMQGTEDK"
     gene            10221..10460
                     /locus_tag="VU722_001617"
     CDS             10221..10460
                     /locus_tag="VU722_001617"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772551.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDKVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10786..11922)
                     /gene="dnaJ"
                     /locus_tag="VU722_001618"
     CDS             complement(10786..11922)
                     /gene="dnaJ"
                     /locus_tag="VU722_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU1772552.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12266..12670)
                     /locus_tag="VU722_001619"
     CDS             complement(12266..12670)
                     /locus_tag="VU722_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU1772553.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGVIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(12681..14504)
                     /gene="dnaK"
                     /locus_tag="VU722_001620"
     CDS             complement(12681..14504)
                     /gene="dnaK"
                     /locus_tag="VU722_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU1772554.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNSDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVIAGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQETGNAGDDVVDGEFTEK"
     gene            complement(14984..15508)
                     /gene="grpE"
                     /locus_tag="VU722_001621"
     CDS             complement(14984..15508)
                     /gene="grpE"
                     /locus_tag="VU722_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU1772555.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15535..16569)
                     /gene="hrcA"
                     /locus_tag="VU722_001622"
     CDS             complement(15535..16569)
                     /gene="hrcA"
                     /locus_tag="VU722_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU1772556.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKAIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVVAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYL
                     YLSSNHYEVH"
     gene            complement(16733..17242)
                     /locus_tag="VU722_001623"
     CDS             complement(16733..17242)
                     /locus_tag="VU722_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU1772557.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSCFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSSFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17850..20183
                     /locus_tag="VU722_001624"
     CDS             17850..20183
                     /locus_tag="VU722_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU1772558.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKSGEHITYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIGD
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLDKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20196..21659
                     /locus_tag="VU722_001625"
     CDS             20196..21659
                     /locus_tag="VU722_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU1772559.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERAALNHKIDNVLADILQLLEDK"
     gene            21659..>21848
                     /locus_tag="VU722_001626"
     CDS             21659..>21848
                     /locus_tag="VU722_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEU1772560.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         6916 a         4492 c         4011 g         6429 t
ORIGIN      
        1 ctgcacaacc taaagcagca actacagctg ctcctccgga attacctccg taaacctcac
       61 tcagcattgt ttcatttata ttacaataag tattcataca agtctccttt tgttaaaatc
      121 cacccgttgc ccctgttact cctgcccaaa gagccacacc aaatttagct cctatgtatc
      181 cacatgctcc cataaatggt gctccaacac cactcgcagc acaaatagct gtccctaacc
      241 cccagccacc aaaagcggca ccaccacctt ctaagacatt agtttgccaa ttattcttgc
      301 ctccttcaat actagataac atagttatat ccataatctc aaattgttcc atcatttttg
      361 tattcatgac aaatactcct tttttatttt ttatttttgt cttgttgtaa ccttgacaag
      421 tttagtatat cattattttt taattttttt catccaaatc ttgaactgtc atcgaaacgt
      481 cttgaattag cttttttatt tcaagccacc tctaaatgtt taaaaaaaat aatttctaat
      541 cactttttta ccattcagga agttttaatg actattcaag atttcataaa atatgaactt
      601 atttttatgg cataatatac ctatccacta tattaaagga attgccaatg acttcttata
      661 aacgtacatt tgttcctcaa atagatgcga gagactgtgg tgtcgctgcc ttagcctcga
      721 ttgctaaatt ctatggttca gatttttctc tagctcactt gagagaactt gcaaagacca
      781 ataaagaagg gacgactgct cttggcattg taaaagccgc tgatgaaatg ggctttgaaa
      841 caaggcctgt tcaagcagat aaaactctct ttgacatgag tgatgtcccc tatccattta
      901 tcgttcacgt taacaaagaa ggaaaactcc aacattacta tgttgtctat caaacaaaga
      961 aagactatct gattattggt gatcctgacc cttctgtaaa aatcaccaaa atgtcaaaag
     1021 aacgcttttt ctctgaatgg actggagtag ctatttttct agctcccaaa cccagctatc
     1081 aaccccataa agataaaaag aatggtctac taagcttcct tcctctgatt ttcaaacaaa
     1141 aatctctcat tgcttacatt gttctctcaa gcttattggt cactattatc aatatcggtg
     1201 gttcttatta tctccaagga atcttggatg aatacatcct aaatcagatg aaatcaactt
     1261 taggaatcat ctcagttggt ctggttatta cctatatcct ccaacaagtc atgagcttct
     1321 ccagagatta tctcctaact gttctgagtc agagattaag tattgatgtg attttatcct
     1381 atattcgcca tatttttgaa cttcctatgt ctttctttgc gacacgtcgt acaggagaaa
     1441 tcatttcacg gttcacagat gctaactcta ttatagatgc cttggcttct accattcttt
     1501 ctctttttct ggatgtttct attctgattc ttgtaggggg agtcttactg gcacaaaatc
     1561 ctaatctctt ccttctttct cttatttcca tccctatata catgttcatc atcttttctt
     1621 ttatgaagcc tttcgaaaaa atgaaccatg atgtcatgca aagtaattct atggttagct
     1681 ctgccattat cgaagatatc aacgggattg aaactataaa gtcgctcacg agtgaagaaa
     1741 atcgctatca aaatatagac agcgaatttg tagattattt ggaaaaatcc tttaagctca
     1801 gtaaatattc tattttacaa acgagtttaa agcagggaac aaaattagtt ctgaatatcc
     1861 ttatcctatg gtttggcgct caattagtca tgtcgagtaa aatttctatc ggtcagctaa
     1921 ttacctttaa cacacttttt tcttacttta caactcctat ggaaaatatt atcaacctcc
     1981 aaaccaaact ccaatctgcg aaggtcgcta ataaccgttt gaacgaagtc tatctagtcg
     2041 aatctgaatt tcaagttcaa gaaaaccctg ttcattcaca ttttttgatg ggcgatattg
     2101 aatttgatga cctttcttat aagtatggtt ttggacgaga taccttaaca gatattaatc
     2161 tcacgattaa acaaggagat aaggttagcc tagttggagt tagtggttct ggtaaaacaa
     2221 ctttagccaa aatgattgtc aatttctttg aaccctacaa agggcatatt tccatcaatc
     2281 atcaggatat taaaaacatc gataaaaaag tcttgcgccg tcatattaat tacctaccac
     2341 aacaagccta tatctttaat ggctctattt tggaaaactt aaccttgggc ggtaatcata
     2401 tgattagcca agaagatatt ctaaaagctt gtgaattagc tgaaattcgt caagacattg
     2461 aaagaatgcc tatggactat caaactcagc tctctgatgg agctggtcta tcaggaggac
     2521 aaaagcaacg aatcgctctc gctcgtgctc ttttaactaa agctcctgtt ttaatactag
     2581 atgaagctac tagcggtctt gatgtcttta ctgagaaaaa ggttatagat aatcttatat
     2641 ccctaactga taaaaccatt ctctttgtag cccatcgtct cagtatagcc gaacgaacta
     2701 accgtgtcat tgttcttgac caggggaaaa tcattgaagt tggtagtcac caagagttaa
     2761 tgcaggcgca aggcttctac catcatctat tcaataaata aggagaatgt tatgaatcct
     2821 aatcttttta gaagcgtcga gttttatcag agacgttacc ataactatgc gacagtgtta
     2881 attatacctc tttcattact gtttactttc atcttgattt tctcctttgt tgccacaaaa
     2941 gaaattactg ttacttccca aggagaaatc gcccctacaa gtgccattgc atctattcag
     3001 tcgaccagtg ataatcctat ccttgctaat catttagtgg caaatcaagt agttgagaaa
     3061 ggtgacttac tcatcaaata ctctgaaaca atggaagaaa gtcagaaaac tgccttagca
     3121 actcaattac aaagacttga gaagcaaaaa gaaggacttg gaattttgaa acaaagctta
     3181 gaaaaagcga ctgatctttt ttctggcgag gatgaatttg gctaccataa tacctttagg
     3241 aattttacta aacaatccca tgatattgag ctaggtatct caaagactaa caccgaggtt
     3301 tcaaatcaag ctaatcttgc caatagcagt tcatcagcca tcgaacaaga aattacaaaa
     3361 gttcaacaac aaattggaga ataccaggag ctgagagatg ctatcataaa taaaagggct
     3421 cgcttaccaa ctggcaatcc gcaccagtca attttaaatc gttatcttgt agccgctcaa
     3481 ggacaaacac aaggaactgc agaggagcca tttttatctc aaattaatca aagtattgca
     3541 ggtctggaat catctatcgc aagcctcaaa attcagcaag ctggtatcgg aagtgtagca
     3601 acttatgata atagtttagc aaccaaaatt gaagtactcc gcactcaatt tttacagaca
     3661 gcctcacagc aacaactaac cgtggagaat caattaacag aattaaaagt acaactagat
     3721 caagcgacac agcgcttaga aaacaatacc ttaacagcac caagtaaagg tatcattcac
     3781 ctaagcagtg aatttgaagg taaaaataga attccaactg gtacagaaat tgctcaaata
     3841 ttccctatca tcacagatac aagagaagta ctaatcactt actacgtagc ttctgactat
     3901 ctacctctac tagataaagg acaaactgta agattaaaac tggagaagat tggaaatcac
     3961 tgcattacca tcatcgccca acttcagaca attgatcaaa ctcctaccag aacagagcaa
     4021 ggcaatctct ttaaattaac cgctcttgca aaactatcta atgaggatag taaactcatc
     4081 caatatggct tacaaggtcg cgtcactagt gtaaccgcaa agaaaacata ttttgattat
     4141 ttcaaagata aaattctaac ccattctgat taattttcag ataacactct ataactattt
     4201 attatcttat caaaaaggag aattgtaaca tggataagaa tcaaaaccta acttcattcc
     4261 aagaactaac aactactgaa ctcaaccaaa ttacaggcgg aggatggtgg aaagatttat
     4321 tacatagatt taatgtaatt gaacaaaaca atacaaaagg atttaatcaa ccaatacaac
     4381 tataaaaaat aagaccgaga aacaagaatt ctcggtctta ttttcatcat tctgtatgta
     4441 tcatagtaag cacctgacga aagacttgat cttgacaggt agtatttaaa ctggcattgg
     4501 gataactttc cacaatcttc ataacggtat agagaccgac acctctctcc tcccctttag
     4561 aactaactcc aaaggagaag atttcagaaa tatcgatgcc ctcttctttg atagaatttt
     4621 caatgataaa ggtctcctgt gctccatttt ttaaaaaggc aattgaaaca tgaggttgac
     4681 tagcctctgc actcgcttca atagcattgt cacaaaggat agacacgatg gttagaaaat
     4741 caagcaggct catcccctcg acctgaatct cctcaggaac ttcgacatta aagataatct
     4801 tcttatctct agcttttaga aatttccctg ctagaagact tttgagggca cggtcacgaa
     4861 tattcaccaa tctgcccagg tcatatttat tgtcctgcaa tttctgactg gaatccttta
     4921 aaacagagtc gtaaacctct tttatctgct ccatatcctc ctcttcaata cccagacgta
     4981 aactggtcaa gaggttggtg tagtcatggc gaaaactcct tacttccttg taaagttcct
     5041 ctatatgccg actatggcgt tccatatctc tatagcgcaa ggtctgctct tggttcagtc
     5101 tctcatggag tttgttcttc aaataggtat ccaatttctt gataaccccc ataaaaaata
     5161 ggaggtagaa cactaggatg agatggcgaa cagtcgttga ttgaatacct tgctcatatt
     5221 caaagtaaga cagactttgt atcaccaaat agtaagcccc cattatccag ttaatcttag
     5281 tcagggactt ttgaaaacct gtatctagaa tctcccttct caaactagta aaatcatagt
     5341 ccaaccattt caaaaaggct agagaaatga agaaattgaa aattattata cataacccag
     5401 tgaatgagta gccatcatat acttgccctt gtcccaaaaa tggaagcaca aaataggaga
     5461 ctcctctata aaagagattc accaatatca ttggaaagag accataaaag aaaaggagtt
     5521 ttttaggaag ccctcttaac aataagaaag acaagcctat gccgtacaag ggttccataa
     5581 aataagatag gtaaacattt cctactatat agctaatcat tacaaaaaca aagaccaaca
     5641 gtatcttcaa aagaaaggcc ttaaaaatcc tctcgaaagt aagattaatt ccatccacct
     5701 taaagaaaat gacaatttct agcccattag taataagtgt atgcaataat atccaaacaa
     5761 tattcataaa ctctcctagt tcagtgtaag ttattaatag cctcagacac ttccctgacc
     5821 ttataacgca cgatcagaca acttccacca ttgggaagga aaaggagttt ttctttctta
     5881 tccaaatgca ccacatttgc aggattgatg agaaaagagc gatggcactg caagagacgg
     5941 ggttcctgct tgaaaacctc ctctaaactc gctgtaaatt ccagcctgtc tgtcttggta
     6001 tagagaataa cacgatgggc tctgggagac atttcgagat agtaaacctc tttaaaagga
     6061 tattggaatt gggcaaattt tgatttaaag taaaagcaat cttccgccag acttttacta
     6121 tcttgactat tggcatagag gagggctgtc tcgatacgag attcaaactc ctctgccgaa
     6181 agggccttat caatgtagtc caaagctgac acttggtagc gaaaggacag aggcataaac
     6241 tccgagtgag tcgtcacaaa gacgattagg gcataagggt cccgatcccg aatctttcta
     6301 gccacttcca gccccttcat ctcctcattt cgaatctcaa tgtccaaaaa gaatagctga
     6361 tgggcccccc ttctcatgca cctctgtcag cagttggtcc ggcttgccaa atacctcaaa
     6421 agagctagga atgatatgat gtgctttcaa aagtttctca atcgtcgttt caattctagt
     6481 ctgttgggaa aaatcatctt ctaaaacaaa tattctcatc ttcttactct ccctctttca
     6541 accatttttg acgaatttct ctatagcgac gtctggcata cttgacagcg tattgacctt
     6601 cttctccgag aaaaaggatt cttttttgaa aatcaatcga ttttaattta tcaagattaa
     6661 ccaaacaatt tcgatgacat ctcatcaagg tttccccata ttggttctca agattactta
     6721 aattttgaag catattaaaa ctagcttctt ctgtaacaat ctgtacggta tgggctttag
     6781 ttggatgtgt ttggatatag tagatatcgt cgacgtttac tttatagact gttttctgcg
     6841 tctgaataat catatgtttc attggattct cctcctaaga aaagaataac agaaaagttc
     6901 tagcccaagc ccacccaatc ctaaacagtc tttgaaagct cctaaaagga ttatttttct
     6961 acaacatcat gatgagctta caactatttt atcataaaat tcactcagcg caattaaaga
     7021 tttgaataaa aaaaaagaat taaaaatgat aaactaacag tatcaaaaca cagttgccag
     7081 aagtaagact ggcacccaga ttaaaggagg aattcccatg acagatacag accctatcaa
     7141 aagagctcag gctttgatta ctgacttaaa caaagcctat caagcatgca aacaggcaag
     7201 cgctgacgac gtccgctttc aggagcaatt aaactctatt cttggttttc tagccaaggc
     7261 tgagacagcg gataatcgag tcttgattga actggaaaaa ttttaccaga cttccagtct
     7321 tctcatggga ctcagcgctc ttgatccaga tgctccaact cgcgccgctt ggcgggccta
     7381 tgaccgcttc cactttgacc aagtcaagac caagttgagc ctctacggtc caaccattat
     7441 cttgtaaaaa ataaaagaag ctgagacaga ttgaactcaa cttctttttt gttccatata
     7501 agcaatgtta gtcctgcatc tgacgtttta cctgataagg caaatacaag acttgtaaaa
     7561 ccaaacctgc acccagcaag gctagaaggg ctagtttttc ttggaaggtc acaaggccga
     7621 caactaattc caccactaag accaaactag tcaatcctcg gactaccgcc tgcaagcctt
     7681 tttccttttg ccccttgtcc agcggaaaaa gttgggtcaa atactggtag tcaaaggcgt
     7741 gatagagggc cagcaactga aagagcaaga ggtagttaaa cagaaccact accgctgtcg
     7801 caatccaaga ttgctcaata aagacctgcg ccagcaaaga aagcaagagc agacggagac
     7861 taagggcaaa aaggtctcca tttcgcaaat aagaacgcag atagagattt tgccaaatct
     7921 tcccaggcac cttctgaaca acctttagaa taaagtccag ataggcacga cgcttgacgc
     7981 tgtttgaaat tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac
     8041 gcttgctttc ttgggaaatg acatagtccc aatccagtcc agtttcagtg aaaaatttgc
     8101 tggccttttg acgaaagagg aaatattttc ctacccccaa taaaagcaca taaaccagaa
     8161 aaacaggcaa gccataaccc atggctaaaa acaagggcgc aaataaaagc aagaagaggg
     8221 tctggacaaa aatccaaaag actagggaaa tgccggtttg acgcttgaga tggagcttga
     8281 tttcctcttc tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc
     8341 ctccccaaag taaaagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat
     8401 tttcaggaaa atgttgtaag agttgactgt actggtaggc tagaaagccc aacagtacaa
     8461 gcaggaacaa gacaaagtgg tcattgagaa catagcgcag ataaccaaga cactccttac
     8521 gaaaggcctg ctttctcttt aaaaacaagt ctttcatagg tcctcctctt ttgtcagagc
     8581 caagtaaata tcattcaaac tagcctcagg catatcaaag gcttcgcgta gttgcaggag
     8641 attgcctttg gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttctc
     8701 cgccgaatcc agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc
     8761 caaaagctga atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac
     8821 gatgaaaaga cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc
     8881 ttttgaaaaa tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa
     8941 gggctctact cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc
     9001 gatatgctct ctgagggtca attccttata cagactaggc gtctcaggaa tgtagccaat
     9061 ctgcttgcgg tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc
     9121 actataaggt gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt
     9181 gagaccaatc aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac
     9241 aggaacatga acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct
     9301 ggtataatgt agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga
     9361 ttgcattttt tgtaaaatca tcgcagggga aatccctgct tcaaaagtat atgaagatga
     9421 gcaggtcctt gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc
     9481 aaaagaacac tatcgcaatc ttttggagat ggatgctacg agcgccagcc aactctttgc
     9541 ccaagtacca aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat
     9601 catttccaac tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt
     9661 gcctcgctac agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt
     9721 tgacaaactt gctcaagttg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt
     9781 atccaaccta ctgctatttg caggagctac agccggaagt tatctggtta caaaaaatcg
     9841 ccaaaccatc acagatgaaa tcttgaatac cactgaccgc gttcaagcta tcaaggacga
     9901 tgtggatatt atccaaaaca gcctgcaaat catcgaccag caaaaagaac ttatcaagga
     9961 ataccaagaa gacttgactt acaagtttaa gatcttggaa aaggatatcc agactagact
    10021 agctgtgata aaagaaatgc agggaactga agataagtaa aaagagcccc cggctctttt
    10081 ttaaaacgta aacaagttat agtgaattga atttagaata gcacatcata gtttctaaag
    10141 cattgttaga gattacttta aaatcctctt atcaatttgt tcatattcta tttcaatcta
    10201 ctatatatat cccatcaact atgcatcata atttaggtaa ctcatactca ataaaaatca
    10261 aaaagcaaac tagaaagcta ggcacagact gctcaaaaca ccgttttaag gttgtggata
    10321 gaactgacaa agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
    10381 gtaaccatac ccatggcaag ccgacactga cgtggtttga agagattttt gaagagtatc
    10441 attcaccatt tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc
    10501 ttggtttcag ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg
    10561 aaggaggtcg ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa
    10621 agagcccgac agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ttagccacgg
    10681 gctgctcaaa acactgtttt gaggttgtag atacgactga cgaagtcagt cacatatata
    10741 cggcaaggca acgctgacgt ggtttgaaga gattttcgaa gagtattatt ctccatcaaa
    10801 ggcatcttta atatggtcaa agaagccttt tttctttgga tttactttca agtcaccagc
    10861 agccgcgaat tctttcaagg ctactttttg gcggtcgttc aagcctgtcg gtgttacgac
    10921 attaacagta acgtattggt caccaactgc accgccacga aggctcggtg cccccttact
    10981 acgtaggcgg aacttcttac cagtctgagt tccctctgga ataaccaatt caacatcacc
    11041 gtgaacagtt ggaatatcta ctgtatcacc aagagccgct tggacaaagt tgaggttgag
    11101 attgtagaag atagtcgttc cttcacgttc aaacttgtcg ctagcttcca cagaaactac
    11161 tacatacaag tcaccataag gtccaccgtt aaagcctgct tcaccttgac cagcgaggcg
    11221 aatttgttga cctgtttcca caccagcagg gattttcaca tgtacgctat gagcttgttt
    11281 ctcatgacct gttccatgac aggttgtaca tggatatttg atttcttttc ctcgaccgtg
    11341 acagacatca caggttactt ggcgacgcat cataccaaga ggagtctgcg tatcgacgtt
    11401 aatgacacca gcgccatgac agcgtccaca agtgactgga ctcgtccctg gcttagcacc
    11461 agagccatta catgtacgac agccagcttc acgatgatac ttaacttcct tctcagttcc
    11521 gaagatagct tcttcaaagg tcaaattgac acgatactgg agatcatctc cttggcgagg
    11581 agcgtttgga ttgcgcgaag aaccgcctcc gccgaagaaa cttgagaaaa tatcctcaaa
    11641 accaccgaag ccacctgccc cattgaaacc gccgaaacca ccagctccac caaaaccacc
    11701 attggcacct gcagcaccat actggtcata ggcagcacgt ttttggtcgt cactcaaagt
    11761 ctcataggct tcttgaactt ccttgtactt gtcctcagca ccaggctcct tgttgatatc
    11821 tgggtgatat tttttggaaa gcttacgata agcctttttg atttcgtctg ccgaagcgtt
    11881 tttggatacc cccagacgat cataaaattc agtattgttc ataattcaag atacaaaggg
    11941 cgtcaaacgg acacagccat ctaggagttt tgacgacgga cgcttacgtc ctagagaaaa
    12001 ctatcttttt ggcacagtcc gtagcccgtg ttcagttacg aacaccctta ttcctttcta
    12061 ttgatgttct gaatcgaacc accatttagg tcggattcaa ttcctttctt ttatatttag
    12121 taagaaattc tgaaacccgt gttcagttac gaacactctt tgttcctttc tattgatgag
    12181 acaaaaccca aacaaatgag attccgtccc tttttatcga aaaacagagg ctgggttgca
    12241 acctctgcaa ataagtaaat taactttatt ttgattttaa atatcctata agtacagaaa
    12301 tatttatata tttttgtctc ttcttagtat ttgctatata attccaattg atcataagaa
    12361 atacaactac tgtccaaatc acaccaatta tgaacggtat tacaaattta tatgtttgta
    12421 tttctaatga tatcatagct gataccagcg ccgatacaaa tgcagacaac aatactgagg
    12481 taacaaaatt ccttaccgct tcatcatttt tgatacaact atcatgttca gctaatataa
    12541 tttctctata tctagctaaa tattctattg gaatattatc aataaaatct tttgatgttc
    12601 tatagttatc agcttgatta caaaaatcat tataaacttt tcgtgtattt tttagatact
    12661 cttcatccaa tacactcgtc ttacttttcc gtaaactctc cgtctacgac gtcatcgcct
    12721 gcgtttcctg tttcttgtgc gccttctgct ccttcttgag cttgttgcgc tgctgcggct
    12781 tgttcgtaga gtttaacagc aagtccttga gctttttcgt tcaatgcttc aagttttgtt
    12841 ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa ggtcatcaag ggcagcttgg
    12901 gcagcgtcac gttctgcgtc gaagccttta ccttcagttt ccttgattgt cttttcagtc
    12961 gcaaagattg cttggtctac ttcattacga aggtctactt cttctttacg tttcttatcg
    13021 gcttcagcgt ttgcttctgc atctttcatc atgcggtcga tttcttcgtc agtcaaacct
    13081 gagttcgatt ggatgacaat agtttgttct ttttgagttc caaggtcttt ggccttaaca
    13141 gacacgatac cgttcttgtc gatgtcaaat gttacttcga tttgaggaat tccacgaggt
    13201 gcagctggga tatcagtcaa ttggaagcgt ccaagagtct tgttatctgc tgccattggg
    13261 cgttcacctt gaagaacgtg gatatcaacg gctggttggt tgtctgctgc tgttgagaag
    13321 acttgtgatt tagatgttgg gattgtagtg ttgcgatcga taagttttgt aaatactcca
    13381 cccattgttt cgataccaag tgacaatggc gttacatcaa gaaggacaac gtccttgaca
    13441 tcaccagcaa tcacaccacc ttggatagcc gcacccatag caactacttc atcagggttt
    13501 actgatttgt ttggttcttt accagtttca gctttaacag cttcaacaac ggcagggata
    13561 cgagttgaac caccaacaag gataacttcg tcgatttctg acaagctcaa acctgcatct
    13621 gaaagggctt gacgaactgg aacttttgta cgttcaacaa ggtcacgagt caaatcgtca
    13681 aatttcgcac gagtcaaagt catttccaag tgaagaggtc cagcctcacc tgcagtgata
    13741 aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt ctttcttcgc tttttcagcc
    13801 gcatctttca aacgttgcat tgccatcttg tcagtagaca agtcgatacc gttttctttc
    13861 ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa agtcgtcacc accaagtttg
    13921 ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac ccaattcaag gatagagacg
    13981 tcgaatgtac caccaccaag gtcaaatacc aatatttttt cttctttgtc agtcttgtcc
    14041 aaaccataag caagagctgc tgcagttggt tcgttaacaa tacgttctac ttcaagacca
    14101 gcaattttac cagcgtcttt tgttgcttga cgttgagcgt cgttgaagta agctggaact
    14161 gtgataacag ctttggttac tttctcacca aggtagtctt cagcgtagcc tttcaagtat
    14221 tgaaggatca tagctgagat ttcttgtgga gtgtattctt ttccatttgc agaaactttt
    14281 tcagaagttc ccatcttaga tttgatagag ataactgtat ctgagtttgt gactgcttga
    14341 cgttttgcag catcaccaac gatgatttct ccgtttttga atgagactac agatggagtt
    14401 gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag ttccttcaag aactgcaact
    14461 gctgagtttg ttgtacctaa gtcaataccg ataattttag acatgtgttt ttctccttgt
    14521 tagttaattt tctatttttc tttttgatac tcttcttaag tggcgacgcc gtcagagctt
    14581 gacttcgtca gtctctttga ctaaactttg agcctaaggt ctcaaaattt gcgcaaatag
    14641 cgccacggcg aagagtatcg tctttggttc gcttcgctca ctattacaaa gcaaaacata
    14701 ttttatcttt cttcatagtt tattgtcgtt tcggacaagt tttctattat gtaaattgcg
    14761 acacgaggag tcgaaatcga ttttatttcg acgacgagtt agtaaggaag ctaggcaaac
    14821 gccatagcaa ttgccgtttt ctgacgagtt gctttagcta ccgtcagaat tgccgaatcg
    14881 aacacgccct aagctctgag taaaaatagg agattttctt gtgttcatcg aacacttcgt
    14941 caatctccta tttttactgc gagcttttta cgggctttgt atcttagtta tacaccacta
    15001 ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc tttttgaaag acttgggcga
    15061 tggtatctac tgggtgttca tcgtctgctg ggagagtttg gatggccata tggtagttat
    15121 ggtcaaattc gccatctgct gcgatttctt caattccttc ttctttcaaa gcgtgaatca
    15181 agctttcttg caccatcccc aagcccttct tcacatcatc tgtcaaacct tcaactgcaa
    15241 gtgcacgctc aaggttgtca agagatggta agattgcttt tgccaagtcc tggctacgat
    15301 aacgttgcaa gttttgacgt tcttcattgg cacggcgttg gatattttgc atttctgcat
    15361 gagcgcgaag atatttgttt tcgaactcat ctgcacgttc atttgccaag tccaactcag
    15421 acttttcagg agttgtttct tcagctgttt ccacaacttc ctcttcttga acttcttcta
    15481 cttcttcatt ttttatatct tgggccatgt tcgcctcctt taatgatttc aatcttaatg
    15541 tacttcgtaa tgattactgc tgaggtagag gtaaaaatct gtcaacttca tggtcaaaac
    15601 acggttgacc acattgactt gattgattag ctgttggtaa tccagattaa ccggaccgat
    15661 aatggctaga attccaactc cccgataagg aatgaggaac ttactactaa tcactgctag
    15721 gtcagctaaa caggattctt gaccgtctgc aacacgaaca ttttgcatct gatcctcacg
    15781 caacccctca cgaatctcca aggccacctt ttgcggttgg tcaaagaact gataggctgc
    15841 tagattggca aaattcaaga gattaacctt gccagccacc acaatgtttt cgttgaacat
    15901 ttccttaaag atgtgttcaa agagatcaat cacattatcc gttgttgtaa agtaacgctg
    15961 gataatctgc ggaatctccg tccgaatctt gtagtgaata tctaaaacag tgtgaccgag
    16021 gaaacgttcc tgaatgattg ccttcagttt cagcaaatcc tcctgcaaga agttccttgg
    16081 aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg gtaaataccg ccaaggctgt
    16141 atgttgcccc aaaacaacga tatcaaaggc tgtcaaccgt tgcctgctcg gctcaacatc
    16201 cagtgccact accgtacagc cactcaggtc tgttagcaag ttagcagcct cttgcagaat
    16261 atcctccaat ttgaagaatt cctgatcaaa ggctttgaca atctcatata cctcattttc
    16321 agccagccgg tcaaaatcca gtgagtgttt cacatagtac tgaaaaccag caacacttgg
    16381 catccgaccg cttgaagtat gagccttctc aagcaaccct tgtttttcta gttccgccat
    16441 gtcattacga atggttgcac tgctagagtt aatagactct tgcaaggctt ttgatccgac
    16501 aggttcgtgc gttttggtaa agatgtcaat aatcagattt aaaatatcct gctgacgctc
    16561 tgtaaccatc tcatcactcc tctctgtctg atcaattagc actcaaggca tccaagtgct
    16621 aacttatgat tctattatac acccttagaa gagaatgtca agacaaaaac tcaaaaaatt
    16681 agcactcttt tatcaagagt gctaaaaatc aatctgaaga cctagaacct tgctattcat
    16741 ctactcggta tttccttttt agtctgaaat aaccatgaat tagataagaa atcagaaaag
    16801 catataaaac aaaaataaga aagaaagaca tagaaagatc ttctctaaac gaactcatac
    16861 aaacaacaag accacctaag aaagtagctg tacaggaacg aagtctagat cgcataactt
    16921 cccatttgag ccccttactc atatagactt gatcctctgg aagtaaatca gaagacgatt
    16981 tacgaagaat cgaacaagaa cctgctccta tcaattccca acctctatct ctaaaatctt
    17041 gcagttcatg cttatatttt ttaagaaatc tagaatcata gatacggtag atgacatcgt
    17101 ctggttgacc ttgctcaaaa tagaacaaac caaaacaact agttctatac ctccaacctt
    17161 tcaaatgcat ctcatgtaaa tactcttctt ccttatccaa atcaacaatg gtgaaaatcc
    17221 gaaattctac tctgctattc attgtcctac cccaaaatta gaaaacatgc ctggcgttat
    17281 ttattagata attctttcca cttttgactc aatctccaaa aaatataaga aatctgaatc
    17341 gcaaaaacta tcaataaaac ccaatctatt atgaaaatca aaaatactcc ccaactgaaa
    17401 gaactacctc cagtgacaaa ctttgagaaa accggtaata gagctaaaaa gagaagcaaa
    17461 ataggaagca tccgcattgt taaaatccgt ttggcataaa aaaatcttta tttaaacgaa
    17521 aatattatgg caaaatttac gccagttttt gaacggctga tgtagatatt ttatactttc
    17581 aaaatgttta aatgtgatta tttatttttg aaaaatagct caccagcccg actgaaagtg
    17641 cttatagaat gataataagt cgcctgccga aaacagcgaa aaatagcggt gttatgcgga
    17701 gataatctga cgcgatgcga aagtatattg catacttatt ttcaacaatt tagcagagta
    17761 tttttataag tgtgatataa tagaagtata atttgttctg atagtttatt ttatggagaa
    17821 gtagattttt agaatgcgga gggttcaata tggttgagtt tataaagtct aagaaagaaa
    17881 tgagtgagga ggatattaaa gcaaatttca tcactcctgc tattgtatcc aaaggatgga
    17941 aaagtggtga gcatatcact tacgaagaat acttcactga tggtcgaatt gaggttagag
    18001 gagataaggc tcgtcgtaaa gaaggaaaaa aatcagacta ttcactgtat taccaatttg
    18061 gaactcgaat tgcaattgtt gaggcaaagg ataataaaca cagcgttcga gcaggattac
    18121 aacaagctat tgaatatgga gagattttag atgttccatt tgtttattct tcgaatggtg
    18181 atggctttat tgaacacgac cgtatcacga gagaagaacg tgagctggag ttagacgaat
    18241 tccctactcg tgaagaatta ttttctcgta tgacgaagga aaaaggattg acgtacgaaa
    18301 ttacagaagc tatctcaact ccatactata cagacgcctt ctcaatgaaa acgccacgct
    18361 attatcagca aatagctatc aaccgtacta ttgaaacagt tgccagagga caaaaacgag
    18421 taatgtttgt gatggcaaca ggaacgggga aaacgttcat ggcttttcaa attattcatc
    18481 gccttcgaaa agctggtttg gctaaacgag ttttattctt agcagataga aacatcttag
    18541 tagaccaaac gatggctgaa gactttaggc cattcgaaaa ggtaatgacg aaaattacac
    18601 caaaactttt gactgctcct gaaaaattaa attcttttga aatttatcta gggctttatc
    18661 agcaactaac tggtgaagat ggaactgaaa cacattatca aaaatttgac aaagacttct
    18721 ttgatttaat cgtaattgat gaagcgcacc gtggttcagc taaggaagac agtaactggc
    18781 gtaaggtgat tgattatttc agttctgcga cacagattgg gatgaccgct actcctaaag
    18841 aaaccaagaa tgcttccaat acggaatact ttggtgagcc aatctatact tatagtttaa
    18901 aacagggaat cgaggatggt tttttggctc catatcgtgt tatgagggtt aatttagatg
    18961 tggatgtgga tggttatcgt ccagaaactg gaaaagttga tgctaacgga caattaatag
    19021 gagataggta ctacggcagg aaagattttg ataaaaccat tgtcattgat gatagaacgc
    19081 aaagagttgc caagtttgtt tctgattata tgaagcaaaa caatgcacga tttgataaaa
    19141 caattgtttt ttgtgttgat attgaccatg ccgagcgaat gcgtgctgca cttgtaaaag
    19201 agaatctaga cttagtccaa gaagactatc gttatgtcat gcaagtaact ggtgacaacg
    19261 ctgaaggaaa agctcaactg gataacttta tggatgtcaa ttctaatttt cccgctatgg
    19321 taacaacgtc taaattatta acgacaggag ttaatgctaa aacatgtcgt ttgattgttt
    19381 tagactctaa tatccaatcc atgactgaat ttaaacaaat tattggtcgt ggcacacgtc
    19441 tttatcctca aaaggggaaa gaatttttta cgattattga ttttcgaaat gttaccaatc
    19501 tgtttgctga ccctgatttt gatggtgagc cagtgaaggt gctggaaaca ggtgcgaaaa
    19561 cagtcagtgg ttctacgcct ggtttcgtag gtgaggaagg tgacccagta gaaaaatata
    19621 tcgttacaga caagcaggtt accattctta attctactgt tcaagtattg gatgaaaacg
    19681 ggaaactgat taccgaaagc ctgaccgact acactcgaaa gaatatctta ggtagctacg
    19741 ccactttgaa cgattttatc acagtttggc atacggcaga taaaaagaag cttatcttag
    19801 acgaacttta taaaaaagga gtttatctag atgctattcg agagtcggag ggaatatcag
    19861 aacaagaaat cgatgatttt gatttactcc taaaacttgc ctatggtcaa aaagaattaa
    19921 ccaaaacgga acgtatcaat aaactcaaac aaagcggata tttatataaa tatagtgagg
    19981 aagcgcgtgc tgttttggaa attttactgg acaaatacat ggataaaggt attggagaac
    20041 tcgaaagcat tgaaacatta aaacttccag aatttcagat atatggtgga accttcaaaa
    20101 tcatcaatac ttattttgga gataaaaaac gatatttaca agcaattaaa gaattggagc
    20161 aagagctatt tacagtagct taatgaaagg aaagtatgtc aattacatca tttgtaaaaa
    20221 gaattcaaga tatcactcga aacgatgctg gtgttaatgg tgatgctcaa cgtattgagc
    20281 aaatgtcttg gttattattc ttaaaaattt atgatagccg tgaaatggtt tgggaattag
    20341 aagaagacga gtatgagtca attatcccag aggaattaaa atggcgaaat tgggctcatg
    20401 ctcaaaatgg ggaacgggta ttgacaggcg atgaattact tgattttgtc aataacaagt
    20461 tattcaaaga gttgaaagag cttgaaataa cttcaaatat gcctattcga aaaacgattg
    20521 ttaaatcagc ttttgaagat gcgaacaact atatgaaaaa tggcgtcttg ttacgccaag
    20581 tcatcaatgt tattgatgaa gttgatttca acagccctga agatcgtcat tcgtttaatg
    20641 atatttacga aaaaattctt aaagatattc aaaatgctgg gaactcagga gaattttata
    20701 cgccacgtgc agcgactgat tttattgccg aagttcttga cccaaaactt ggagaatcaa
    20761 tggcagacct tgcttgcgga acaggaggct tcttgacttc gactctgaac cgtttaagta
    20821 gtcaacgtaa aactagtgaa gatacaaaaa aatataatac agctgttttt ggtattgaaa
    20881 agaaagcatt tcctcatctt ttagcagtta caaatctgtt tcttcacgaa attgatgacc
    20941 ctaaaattgt tcatggaaat actttggaga aaaatgttcg tgaatatacg gatgatgaaa
    21001 aatttgacat tattatgatg aatccacctt ttggagggtc agaattagaa acaataaaaa
    21061 ataactttcc agcagaatta cggagttctg aaacggctga tttatttatg gctgtcatta
    21121 tgtatcgttt gaaagaaaat ggtcgtgttg gagttatttt acctgatggt tttctatttg
    21181 gtgaaggtgt aaaaactcgc ttgaaacaaa aactggtaga tgagttcaac ttgcatacga
    21241 ttattaggtt gcctcatagt gtctttgcac cgtatacagg aatccatacg aacattcttt
    21301 tctttgataa aacaaagaaa acagaagaaa cttggtttta tcgtttagat atgccagatg
    21361 gttataaaaa tttctctaaa actaagccga tgaagtcaga acacttcaat cctgttcgtg
    21421 actggtggga aaatcgtgaa gagattctgg aaggtaagtt ctacaaatct aaatcattta
    21481 cacctagtga attggctgag ttgaattata atttagacca gtgtggtttt ccaaaagagg
    21541 aagaggaaat cttaaatccc tttgagttga ttcagaatta tcaagcggaa agagcggctt
    21601 taaatcataa aattgataat gtattagctg atattttgca gttgttggag gataaataat
    21661 gacaccagaa caacttaaag caagtatcct tcaaagagcg atggaaggga aattagtgcc
    21721 gcaaaatccc aatgacgaac ctgcaagtga attgttaaag agaattaaag ctgaaaaaga
    21781 aaaacttatc agtgaaggaa aaatcaaacg agataaaaag gaaaccgaga tatttcgtgg
    21841 tgatgatg
//
LOCUS       DAVFJR010000035        20885 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVFJR010000035 DAVFJR010000000
VERSION     DAVFJR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.036"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(193..2190)
                     /gene="metG"
                     /locus_tag="VU722_001627"
     CDS             complement(193..2190)
                     /gene="metG"
                     /locus_tag="VU722_001627"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU1772561.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEVVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2314..3573)
                     /locus_tag="VU722_001628"
     CDS             complement(2314..3573)
                     /locus_tag="VU722_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772562.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3575..4276)
                     /locus_tag="VU722_001629"
     CDS             complement(3575..4276)
                     /locus_tag="VU722_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772563.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4260..5459)
                     /locus_tag="VU722_001630"
     CDS             complement(4260..5459)
                     /locus_tag="VU722_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU1772564.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5745..7091
                     /gene="gor"
                     /locus_tag="VU722_001631"
     CDS             5745..7091
                     /gene="gor"
                     /locus_tag="VU722_001631"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU1772565.1"
                     /translation="MKEYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTVKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7288..7824
                     /locus_tag="VU722_001632"
     CDS             7288..7824
                     /locus_tag="VU722_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU1772566.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7875..7961
                     /locus_tag="VU722_001633"
                     /pseudo
     CDS             7875..7961
                     /locus_tag="VU722_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8030..8245)
                     /locus_tag="VU722_001634"
     CDS             complement(8030..8245)
                     /locus_tag="VU722_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU1772567.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8343..8663
                     /locus_tag="VU722_001635"
     CDS             8343..8663
                     /locus_tag="VU722_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772568.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8693..9031)
                     /locus_tag="VU722_001636"
     CDS             complement(8693..9031)
                     /locus_tag="VU722_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772569.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVECATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(9043..9762)
                     /gene="trmD"
                     /locus_tag="VU722_001637"
     CDS             complement(9043..9762)
                     /gene="trmD"
                     /locus_tag="VU722_001637"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU1772570.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9752..10270)
                     /gene="rimM"
                     /locus_tag="VU722_001638"
     CDS             complement(9752..10270)
                     /gene="rimM"
                     /locus_tag="VU722_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU1772571.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10316..11089)
                     /locus_tag="VU722_001639"
     CDS             complement(10316..11089)
                     /locus_tag="VU722_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1772572.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAII"
     gene            complement(11666..11905)
                     /locus_tag="VU722_001640"
     CDS             complement(11666..11905)
                     /locus_tag="VU722_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU1772573.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11925..12197)
                     /gene="rpsP"
                     /locus_tag="VU722_001641"
     CDS             complement(11925..12197)
                     /gene="rpsP"
                     /locus_tag="VU722_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU1772574.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12367..12576
                     /locus_tag="VU722_001642"
     CDS             12367..12576
                     /locus_tag="VU722_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772575.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            13055..13276
                     /locus_tag="VU722_001643"
     CDS             13055..13276
                     /locus_tag="VU722_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772576.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            13359..14162
                     /locus_tag="VU722_001644"
     CDS             13359..14162
                     /locus_tag="VU722_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU1772577.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITVDSIEVVKDYDFKS"
     gene            complement(14218..15759)
                     /locus_tag="VU722_001645"
     CDS             complement(14218..15759)
                     /locus_tag="VU722_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1772578.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERHQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKCALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(15761..16243)
                     /locus_tag="VU722_001646"
     CDS             complement(15761..16243)
                     /locus_tag="VU722_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU1772579.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(16243..17328)
                     /gene="rlmN"
                     /locus_tag="VU722_001647"
     CDS             complement(16243..17328)
                     /gene="rlmN"
                     /locus_tag="VU722_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU1772580.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRTDQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(17349..17879)
                     /locus_tag="VU722_001648"
     CDS             complement(17349..17879)
                     /locus_tag="VU722_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU1772581.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(18035..18640)
                     /locus_tag="VU722_001649"
     CDS             complement(18035..18640)
                     /locus_tag="VU722_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU1772582.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(18813..19850)
                     /locus_tag="VU722_001650"
     CDS             complement(18813..19850)
                     /locus_tag="VU722_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU1772583.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(19884..20819)
                     /locus_tag="VU722_001651"
     CDS             complement(19884..20819)
                     /locus_tag="VU722_001651"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU1772584.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
BASE COUNT         6082 a         4551 c         3834 g         6418 t
ORIGIN      
        1 catgttttga gctgacttcg tcagtttcat ctacaacctc aaaaacatgt tttgagctga
       61 cttcgtcagt tctatctaca acctcaaagc agtgctttga tcaacccgcg gctagcttcc
      121 tagtttgctc tttgattttc attgagtata aataaaaaaa acagaactag tctgaactag
      181 tcctatctac ttttacccaa tcacacttcc atttggtaca gctggatcaa ctgtgagaag
      241 ggttaatttg ccatcatgtt cagctgagag aatcataccc tggctgacat attttttcat
      301 cattttacgt ggtttgaggt tagcaacgat ttgaactttc ttgccgacca attcttgttc
      361 atttggatag tattttgcaa ttcctgaaag aatctgacga tcttctccat caccagcatc
      421 caagcggaat tgaagcaact tatctgaacc ttccacttta gacacttctt tgacttctgc
      481 gacacggatt tcaaccttgt caaagtcttc aaacttgatt tcatccttgt ttagtttgag
      541 ctcaacttcg tccggattcc attctttttc gactgctggt ttattgcctt ccatttgttc
      601 cttgatatag gcgatttctt cttccatatt tagacgtgga aagataggtg ttcctttggc
      661 aactacagtc acatctgctg ggaagtcagc caaactcaag ttttcaagac tagaaacttc
      721 ttccaaacca agttgagtca aaactgcacg actagtttcc atcataaatg gttcaatcaa
      781 gtgagcaact acacgaatgc tggctgccaa gtggctcatg acacttgcca attggtcacg
      841 aagagcttca tccttggcca agacccatgg tgcggtctca tcgatgtatt tattggtacg
      901 agagatcaga gtccagactg cttcaagcgc acgtggatag tcaactactt ccatgtgtgt
      961 atggaagtct gcgattgatt gttctgcaac ctcagcaaga acatgatcaa attcagtcac
     1021 accttctaca taggcaggga tttgtccatc aaagtactta ttaatcatgg aaaccgtacg
     1081 gttaaggagg ttcccaaggt cattagccaa ttcatagttg atacggccga catagtcttc
     1141 aggagtaaag gttccgtctg aaccaactgg aaggttacgc atgaggtagt aacgaagtgg
     1201 atctagtcca taacgctcta ccaacatttc agggtaaacg acattccctt ttgacttaga
     1261 catttttccg tctttcatga caaaccaacc atgggcaatc aaacgatcag gtaatttaac
     1321 atccaacatc ataagaagga ttggccagta gatagagtgg aagcgaagga tgtcttttcc
     1381 taccatatgg aagactgttc cattccagaa cttgtcaaag ttaccatgtt cgtcttgagc
     1441 gtagccaaga gctgtcgcat agttaagaag ggcatcaatc caaacgtaga caacgtgttt
     1501 tggatttgat gggacaggca ctccccatgt aaaggttgta cgagataccg ccaaatcttc
     1561 caaacctggc tcgatgaagt tgcgtagcat ttcattaagg cgaccctctg gcgtgataaa
     1621 ttcaggatga gctttgaaaa attcgaccaa acggtcttgg tatttgctaa ggcgaaggaa
     1681 gtatgattct tcagaaaccc attcaacctc atgacctgat ggagcaatac caccagtcac
     1741 atttccagct tcatcacgga aaacttctgc cagctggctt tctgtaaaga attcttcgtc
     1801 tgatactgaa taccaaccag agtattcacc caagtagata tcatcttgag caagtaagcg
     1861 ttcaaagacc tgtgcgacaa ctttttcatg gtagtcatcg gttgtacgga taaatttatc
     1921 gtatgagata tctagtaatt gccagagttc tttaactcca accgccattc catcaacata
     1981 ggcttgaggt gtaataccag cttcttccgc tttctgctgg attttctgac catgttcatc
     2041 aagacctgtc agataaaata catcgtagcc catcaggcgt ttgtaacgtg ctaggacatc
     2101 acatgcgata gttgtgtagg cagaaccgat atgaagtttc ccagatggat agtaaatcgg
     2161 cgttgtaata taaaaatttt tttcagacat aatttttcct ttccaggcaa atgaaacctg
     2221 tttttctaac acttcattat atcacatttt taatgaattt cgatagggaa atccatacaa
     2281 aaacaagata gacgagtgtc catcttgttg atctcattca taacgaaggg cttcaattgg
     2341 atcaagtttc gatgccttgt tggctggcaa gactccaaaa atcataccaa cactagccga
     2401 aactgcaaga ctaaataggg caactgggat tgatactcca acttctatac cttctattaa
     2461 accttgcagt aacaaacctg ctaaggcagt taaaccactt gcaattgtca agccaattaa
     2521 gccacctaac aaggtcaaaa tcatggattc aatcaaaaac tgaattaaaa tattggcacg
     2581 tgttgcaccc aaagccttac gaagaccaat ctcacgagtg cgctctgtca ccgaaaccag
     2641 catgatgttc atgacaccag ttcctccaac aaagagagaa atccctgcga tggaactaat
     2701 aatcgtcgtc ataaaactaa acgattgttg aatttctgca aatacaacgg actcatctgc
     2761 cacctggtat tctccctgtt gtaagcctgc aagctctgtc atttttcgtg ccagttctgg
     2821 acccagagtt ggggttaaac tggtatcatt cactcgaaag acaatattag ctatttcatc
     2881 tacattaaaa ttcgcagcaa gggagatatt ggtagtaata ggcaagccac caaacccata
     2941 tatttttgat cttttagcct ccggactagt ataaacccca atgacccggt aactaaatcc
     3001 attgacttct acaaccttgt taatagcctc ttgaggagat tcaaataaac taatggacaa
     3061 ttcctcatct agcaaaatga cacttgcaaa ctctttgaaa tcttgctctc tcagactacg
     3121 acctgcaata atttcattct taacagcgtc catgtaagtt ctgtttccac ctgtcaaatt
     3181 agcattctca acctttttat cttgataggt caagatggca ttcgttgaat tggttacata
     3241 gtaactatcc actcccttca gtttagctgc ctcttggacc caggattctt gcggttttgg
     3301 cggttcaaca ggaacttcct cttcctttcc agaaaccgta aaagctgatt gtttctgagt
     3361 aaaagacccg tctttacttt ttttaggaga gaaaaagacg ctaatatttt tctgagattt
     3421 agtcatatct ttattgactt gacgagatag ggaatcaccc aaagccataa tcacaacaac
     3481 tgatgaaaca ccgataataa tcccaatcat agtaagcaaa gaacgcatct tgtgagccat
     3541 gatagatgaa aaggcaaatt tcagattctg catcttagtt ttcctccttt cctaactgag
     3601 cactgtcaga cgaaatgacc ccatcccgaa tgacaatctg acgtttggca taggcagcaa
     3661 tctcaggctc atgcgttacc atgataatgg tttttccttc tttattcaaa tcaaccaata
     3721 attgcataat ttggttacct gttttggtat ccaaggctcc tgtcggttca tccgctagga
     3781 taatagaagg attgtttacc aaggcacgcg caatggctac acgttgcttt tgaccaccag
     3841 ataattctga aggtaaatgg tgactacgtt ctgtcaattc aaccttgtct aaatattcct
     3901 cagccaactt gcgacgtttt gaagacgaaa ctcctgcgta aatcaagggc aattctacat
     3961 tttgcagagc attgagcttc gatagaagaa agaactgctg aaagacaaaa ccgatttgtt
     4021 ggttacggac cttagctagt tgtttttcac caagcccagc cacttcttga ccttcaagat
     4081 aatattctcc actggttggt gtatccaaca tgccaatcgt attcatcaga gtggacttac
     4141 cagacccaga tggtcccatg atggctacaa attcaccctc attcacttct agattgatat
     4201 ttttgagaac ctgcagttct tggtcaccat tacggtaact tctgaagata ttttttagac
     4261 taattagttg cttcatcagc cttcacctct tttccttctt ccaaggaaga tgttggatta
     4321 ctgatgacct tagcaccgtt cgttaaacca gaagtgattt cttgattttc tgcgtcagca
     4381 tttcccaatg aaacctcaac ttttttagcc ttttgttgtt catccacaat ccagacataa
     4441 tttttactat catccattac tagactgcta acaggaacaa gaatagcctt agttttgctt
     4501 ttaacctcaa tgttgacaga aaaaccttgt ttcaaatcac caacctcgcc tgtcacatca
     4561 atagtataag ggtatttaga acctgtatta ttcccggctg ctggactagc tgcttcacca
     4621 ttgtttttag gatagtcaga aatatagctt aatttcccag tccatttttt atcaggatac
     4681 actttagaag taaagcttac ttcttgacct acagaaaggt tggctagatt gtactcagac
     4741 aattctccct tgacttgtaa attttcattg ctgacaatat gaaccataac ttggctcgcc
     4801 cctgttggag atttagaaac attgctattg acttcgacta cagttccctc tagggtactg
     4861 agaacagttg ttgcatccaa ttgactttga gccttgctta attgcgccgc agcatctgca
     4921 cgcgcatcac gggcatcacc caattgagcg tcaatagaag caacagaatt tccagccact
     4981 ggagttgggc tttgcaccgt tgcatcttct cctcctactg gcgctggtaa ctgtggagcc
     5041 ggagctgaag cggcttcatt tcgtgcttga ttgagttcat tgatatgacg atctgcctta
     5101 gctactgctc gactagctga atcataggcc gcctgcgctt ctgaactact gtacttgact
     5161 aaagcctgcc cttcgctgac cttatcgccc acagaaacaa ggatttcatc taaatcaccc
     5221 ttactagcat caaaataaac atattgttca ttttttgctg ttactgtccc tgacaataaa
     5281 acagaggatg ccacgcttcc ttccttggca acaacaagat gagtaggctc atcttttaga
     5341 gcagtctgag aaggttgtct aaagagtaaa atccccccgg cacccaatac aactacactc
     5401 gcagcaccga ttgctgcata cagttgccac tttttagctt taccattctt tttcttcata
     5461 atgaaactcc ttttcttgtt tacaatactt tgctattata ccaaatttcc ctccagcaaa
     5521 caatgcagtt cagatggaaa taatggcagt tcaggattaa acaatcgttc ggaattttgc
     5581 ttttctattg tactagatat ataatacact atcttgactt atttggcaag cttttttgca
     5641 attttttgtg cgtagcagat ttttgcaatc aaatcaaaaa aagaataaaa tataactatc
     5701 aaaaaagacg ctctactatt taaaagatta caaaggagtt ttcaatgaaa gaatatgata
     5761 tcattgctat cggtggaggt agcggaggaa tcgctaccat gaaccgtgct ggtgaacatg
     5821 gagccaaagc agccgttatt gaggaaaaga aattaggtgg aacctgtgtc aacgtcggtt
     5881 gtgttcctaa aaaaatcatg tggtacgggg cgcaaatcgc tgagactttc catcaatttg
     5941 gagaagacta cggctttaag actactgatc ttaactttga ctttgcaacc ctacgtcgca
     6001 atcgtgaagc ctacattgat cgcgctcgtt cttcttatga tggtagtttt aaacgcaacg
     6061 gtgtagactt gattgaaggt catgctgaat ttgtagattc tcatactgta agcgtaaatg
     6121 gtgaactgat tcgtgctaaa catatcgtga ttgctacagg tgcccatcca agtattccta
     6181 atattcctgg tgctgagcta ggtggctctt ctgatgatgt atttgcctgg gaagaacttc
     6241 cagagtcagt tgccattcta ggcgctggtt atatcgccgt tgaattagct ggcgtactcc
     6301 acacttttgg tgtcaagaca gatctctttg ttcgccgcga tcgtccttta cgtggttttg
     6361 attcctacat cgttgaaggt ttggtcaagg aaatggaaag aataaacttg ccacttcata
     6421 ctcacaaagt ccctgccaag ttagaaaaaa ctgctaaagg cattaccatt catttcgagg
     6481 atggtaccag tcacacagct agccaagtta tctgggctac aggtcgccgt ccaaacgtta
     6541 agagcttgca acttgaaaaa gctggagtga ctctgaatga acgtggcttt atccaagtag
     6601 atgaatacca aaatactgtt gttgagggaa tctatgctct aggtgatgta acaggtgaaa
     6661 aagaactgac tccagttgca atcaaggctg ggcgtaccct atctgaacgt ctctttaacg
     6721 gaaaaactac tgtaaaaatg gattactcaa ctattccaac tgttgtcttt tcacaccctg
     6781 ctatcggaac tgttggtttg acagaagagc aagctattaa agaatacggt caagaccaaa
     6841 tcaaggttta taaatcaagc tttgcatcta tgtactctgc ttgcactcgc aaccgtcaag
     6901 aatcccgttt caaactcata acagctggtt cagaagaaaa agttgtcgga cttcatggaa
     6961 ttggctacgg cgttgatgaa atgattcagg gatttgccgt tgctatcaaa atgggagcaa
     7021 ccaaggctga ctttgatgca actgtggcaa ttcacccaac tgcatctgaa gaatttgtaa
     7081 ccatgcgtta atcgaaacaa aagaagctga tataaatatg tctgcttctt ttttaatgat
     7141 tttcgaatca acaaaaaaat tatccaactt gactagtcac gaaaatcggc tgttacagtt
     7201 tttgttacct tgtttttaaa aaatggttga catcgactcc tatatgagta taatagttac
     7261 tatacattag aaaagaggtt aactattttg aaaaaagctc acgtttatgc tatccctgct
     7321 attggggctg ctctcattgc tgttttggca caaatcagtc ttccaattgg acctgttccc
     7381 ttcactctgc aaaactttgc aatcggcttg attgctactg tctttagacc gagagaggct
     7441 gtactttctg ctggactcta tcttcttcta ggtgctatcg gtcttcctgt ctttgcagga
     7501 ggtggagctg gttttcaggc tttagttggc cctactgcag gctatctttg gttttatctc
     7561 gtttactctg gacttacttc ctctctaacc aacagcaaga gtggtgttgt taagattttt
     7621 cttgcaaacc tcttgggtga tgcccttgtc tttgtcggcg ggattctcag cttgcatttc
     7681 ctagctggaa tggcatttga aaaagctctt gttgtggggg ttcttccctt tatcattcca
     7741 gaccttggca aacttctggc tattagtttt attagccgtc ccctacttca acgccttaaa
     7801 aatcaggctt actttactaa ctaaaaaagg atatcgagtt atcatgactc aatatccttt
     7861 tcttttattt tgaaaactta tactcaatga aaatcaaaga gcaaactagg aagctagccg
     7921 caggctgctc aaaacactgt tttgaggttg tggatgaaac tgacgaagtc agtaaccata
     7981 catacggcaa ggcaaagctg atgcggtttg aagagatttt cgaagagtat tagttgcctt
     8041 taaaggcatc caccatcgtt tgaaattctt catttgagag agtaatccct ttgcccattt
     8101 tagtatggtc tggactccaa gcacgaatat caaactttgc aggggcacca ttaaagctca
     8161 cacggttaat ttccttggtc caaccttttt cgttttcaga aagagtcaac aagtgctctt
     8221 cgatttcaaa tgtaaattct gccattttct tctccttttt tagtttcatt agtttattcg
     8281 taaaatcttg tagattttag gaaaatttta tataatattg atataaaaga agggaggcca
     8341 atatgagaca taaattccag caagttctaa ataaaataca tgatttttta aatggatatg
     8401 accaacctga ccagactgaa accaactccc ttacagccac tattgaagag gctatccaga
     8461 aacaaaccgc tgttcacctt atcttatctg agacaagctt tacaggtgac atcatcaaat
     8521 atgatcagca aggccagcaa attatcgtga aaaatttttc caaaaatgtg agccggatta
     8581 tccgtataag cgatattcaa cgcctgcgat ttgtcccctc aactgtccaa acagcccaaa
     8641 aaaatagatt taagaaagag tgagatgtag ttgcttcatc ccactctttt tcttagcgaa
     8701 tttgttcaaa atgtaaatga actgcgatat gatctccata accacttctt tccaagtcac
     8761 gttgtaaacg ataggaaata tagtgttctg caatggtaat gtaacctgcg cccaataaac
     8821 gatgttcaac catagattga atcatactga tagtcgcaca ttccaccttg gcttcttgta
     8881 aatccaaaac taccttctta gtgacttgag caagattttg acgcaaatca tctgtcaaaa
     8941 cataaacagt ttgggctgcc ttcaagatgg cttggtaaat cttatctgga ttaaattcag
     9001 caatttcgcc attacgtttg attacttgca taggtttctc ctttattctt tgttttcttt
     9061 gatttctgcc agcatttttt cttcttctac tgtcagttga taatgttcaa gtaaatctgg
     9121 tctgcgctcg taggttttct ttaaactctc gtacaatcgc cactgacgaa tcttttcatg
     9181 gtggccactc atcaatacat ctggcacgac catgcctcga taatcatagg gacgtgtgta
     9241 ctgaggatat tctaaaagac ccgaagaaaa actatcatct tggtggctag actccttgcc
     9301 aatcacttct ggaatcaggc gaactgtagc atcaatcatg gtcatagctg ccaattctcc
     9361 accagtgagg acatagtcgc ctagggaaat ctcatctgtt accaaggtct taatgcgctc
     9421 atcataaccc tcatagtgcc cacagataaa gattagctct tcctcttgag ccaaatcttc
     9481 agcataagcc tgatcaaact gctttccagc aggatcgagg agaataacgc gcggattttt
     9541 cttttcaata gcatcaaagg aatcgaaaat aggttgtgct ctgagcaaca taccctgacc
     9601 gcctccgtag ggctcatcat ctacatgacg ggccttttca gcattttctc gaaaattatg
     9661 atactggata tccaagagcc ctttttctcg agcctttcca acgattgagt gctccagtgg
     9721 agaaaacatc tctggaaaga gggttaaaat atcaatcttc atcgtctaac ccttctaaga
     9781 tttccacatc gacccgttta tttggaatat caacattgag aaccactggt gggatataag
     9841 gtaaaagcaa atcacgtttg ccttttcgtt tgaccaccca gacatcatta gcacctggtt
     9901 gcaggatttc cttgatggtt ccaaccaagc tatcaccctc atagacttcc aaaccgataa
     9961 tctcgtgata gtaaaattca ccatcgtcta ggtcattcaa atcttcctca gcgaccttga
    10021 gactatatcc cttgtacttt tcgatagtat tgatatggta catatctttg aatttaataa
    10081 tgtcaaagtt cttctgttta cggtggctag cgatggtcac tgtttggaca aactgatctt
    10141 tttcatcaaa caaagccagc tcagctcctt ttttaaaccg ttcttctgca aaatccgtca
    10201 cagacaagac tcgcatctca ccctgtaatc cctgcgtatt aacgattttc ccaacattaa
    10261 agtagttcat cttgtctcct gtaatctcct tttttccatc ttattctgac aattctcaaa
    10321 taatagccgc aattttttcc gattctgacc attgtaaata atggtgattc cctcctaaaa
    10381 tgagtttagt attggaagtc caatattctg attctctgta ctctttttct ctataaggct
    10441 gacaaaaaac aaatacagga atatgagctt ctatagatac atcctcaaaa tcttcctcag
    10501 taatctctcc agatatctga aattctggat cttgattttc caactctaag cctttttctt
    10561 gcattaattc ccagattttt ttattcgttt caggactaaa tgttgcttga gttaagttct
    10621 taaaataaag ttcaggacca cactcgtcaa tcagcctcat ctgctcttcc atttctggat
    10681 aaggattttc tgaaaaatca gcaaacatga cttttttagt tgtcggttca attgctacta
    10741 aagtctgacg cttaattggt ttctcgagta atttgcaagc taaaattcca ctccaactat
    10801 gtgcacaaag tatatattca gaaattccta attcttcaag tacttcataa accgcatctg
    10861 caagattatc tagatttttt ccagcttggt catgaatcgg actcctacct gtgttcggaa
    10921 aatcaattgt caaataacca attgtaggag gaggtttttc aagtataagt gaaaaatttt
    10981 cataacttgg tagcaaacct gctccgttta gacaaactag cactttcttt tgcttttgat
    11041 aagtaacaga gaggctacca atttctgtag atacttcaaa cctcttcata aagaaatcca
    11101 ctcattctat ataatgaatt attaaaaatc cttatccttt attttatcac gttccaagga
    11161 ttttctcaag ttggaggaaa gggacaacat ctctactttc ccttcaagaa tccttccaaa
    11221 ttatgtttat gttggtaatt aacggctgcg gttttgtctt tctcaaagac agtcttggta
    11281 aggtcaatat gattaatagc tacgattgcg acggtgtagt aaatgatatc agccagttct
    11341 ctggcaagtt cctcgttcga atcctatccc ttcttttcga ccagagcgcc tattcaaaac
    11401 ctcggctact tctccgactt cctccactaa cttcataaag agaccttcat cagtccgaga
    11461 ctgctgttaa tgttcgagta agtagtcttg gaattgccta aacgttcaat cttttatagt
    11521 atattgaaac tagaatagta cacctttact tctaaaacat tgttagaaat cgatttgact
    11581 gtcctgatcg atttgtcctg ttattatttc tttttactat atcttctatt ccacacaaaa
    11641 aagcgagaca tccgtcccgc ccttcttatt tttcgtcaat aacgattctt acttttttgt
    11701 attcagttgg gacagagtag acaatcgttc ttatcgcaga aatagtgcga cccttacgac
    11761 cgattacacg acccacatcg ctttgatcaa gattcaaatg atattccaaa aattctggtg
    11821 tatcctcaat cttgatagtt aaggcatctg gttgtgaaat taagggtttc acaatcgcaa
    11881 taatgagatt ttcaatcgta tccatctgtc aacctacttt aaacttattt tgagaattta
    11941 gaatcgtgga attttttcaa tacgccttct tttgaaagga tgttacgtac tgtgtctgaa
    12001 ggttgagctc cattagccaa ccatgcaaga acgcggtctt ctttcaaagt tacttggttt
    12061 tcagcaacaa gtgggttgta agttccaact gtttcgatga aacgtccgtc acgtggtgaa
    12121 cgtgaatctg ctacgttgat acggtagaaa ggttttttct tagaacccat acgagtcaaa
    12181 cggattttaa ctgccatttt taaagtctca tttctttaat tttttatttc ggtgaaatag
    12241 ctgagctatt tagcacatgt tctattatag cagatttctg gcaggtgtca agaaaaaaac
    12301 ttgacagact ataaatttct taaagcattt agaaatttgt tagaatagga aataaatgtt
    12361 tgaaagatgc tatccgtgaa tactatttta gaaaaatttt ataaagaaca ccaagtcaaa
    12421 cccttcatat cgcctgaacg agatttggat acttggcttc taagtcccaa acccgttccc
    12481 aagcgaaata tggacttatt agcagatgat tcactagcag gagatatcat tttactatgg
    12541 agaatccagt ttggtacttt taccactgaa acatgatttt aaaaactccc attcgaatat
    12601 gattcaaaat tcgcttagaa tcaatgtttt cccacttttt caaaaaataa attttcatct
    12661 aatttaaata actttcaatt aagtgtgaat tttgcttaaa atcataaaaa aacaccccat
    12721 ggtgtgaacc atgaagtgtt gtaaatgctg tattgtagct agttcttaac gtttagagaa
    12781 ctggctagct ttacgagctt tcttaagatc tggttcccta aatactttga gtacacttat
    12841 ggcattgatg cccctaaaca tctaaaaact ctggtagaaa aagagtatgc tcttgtcgaa
    12901 acttcttttg actcacttga ccatctaaat actaccatga aaaagaatat cctgaagaag
    12961 aagggagtta ctggactttc taaaatgaaa tcttgcgacc tggatcaagc tcttcatgag
    13021 catttttcag aagaagaatt agctggtcac tttcatgtcc ttctatggac ttttttacaa
    13081 tggcattgct atcacaccca atacctatct aagcgcctgg ttcgtaaact ttattgcagc
    13141 tcttcctcta aatttcctaa ttgttgaacc aattgcccgt tttatactaa gttcttttca
    13201 gaaaccattt actggggaag aagttgaaga agttgaagat tttcaagatg atgatgaaat
    13261 cccaactatt atctaagcca gttctgtaaa ctactaatat ttgaaatcca cttcctttta
    13321 gggtacaatg gtataaatga atttttgaga ggaacagaat gaaaaaacta gcaacccttc
    13381 ttttactgtc tactgtagcc ctagctgggt gtagcagcgt ccaacgcagt ctgcgtggtg
    13441 atgattatgt tgattccagt cttgctgctg aagaaagttc caaagtagct gcccaatctg
    13501 ccaaggagtt aaacgatgct ttaacaaacg aaaacgccaa tttcccacaa ctatctaagg
    13561 aagttgctga agatgaagcc gaagtgattc tccacacaag ccaaggtgat attcgcatta
    13621 aactcttccc taaactcgct cctctagcgg ttgaaaattt cctcactcac gccaaagaag
    13681 gctactataa cggtattacc ttccaccgtg tcatcgatgg ctttatggtc caaactggag
    13741 atccaaaagg ggacggtaca ggtggtcagt ccatctggca tgacaaggat aagactaaag
    13801 acaaaggaac tggtttcaag aacgagatta ctccttattt gtataacatc cgtggtgctc
    13861 ttgctatggc taatactggt caaccaaaca ccaatggcag ccagttcttc atcaaccaaa
    13921 actctacaga tacctcttct aaactcccta caagcaagta tccacagaaa attatcgaag
    13981 cctacaaaga aggtggaaac cctagtctag atggcaaaca cccagtcttt ggtcaagtga
    14041 ttgacggtat ggatgttgtg gataagattg ctaaagccga aaaagatgaa aaagacaagc
    14101 caactactgc tatcacagtc gacagcatcg aagtggtgaa agactacgat tttaaatctt
    14161 aaaaaccaaa aaaatacagt atccacattc ggtactgtat ttcttttact ctcattctta
    14221 agttaaatta ttaaaatccc atatttggtc tatccagcct tcataaaagt ctggctcgtg
    14281 gcagaccata aggatagatc ccctatattc tttgagagcg catttgagct catcctttgc
    14341 atccacatcc aaatggttgg tcggctcgtc cagcactaaa acgttgtttt cacgattcat
    14401 caagagacag aaacgaacct tggcttgctc tccccctgat aatacttgaa tctggctttc
    14461 aatatgtttg gttgtcaaac cacaacgggc aagggctgca cggacttctg cttgattaag
    14521 ggcaggaaag gcattccaga cagcttcaag aggagtttgg cgattaccac cttctacttc
    14581 ctgttcaaaa taaccaagtt ctaaataatc tccacgctcc acttccccag cgattggcga
    14641 gataatgccc aagagactct tcaagagagt tgtttttcca ataccattag caccaataat
    14701 cgcaaccttt tgattgcgtt cgaaggtaag atttaaaggc ttagtaagag gacggtcgta
    14761 accaatttgc aagttcttgg cttggaagat aaagcgccct ggtgtacgag ctggtttgaa
    14821 atcaaaggat ggttttggtt tctcactttg gagttcgata atatccatct tatccaattt
    14881 cttttgacga gacatagcca tattacgagt tgcaacacgg gctttattac gagccacaaa
    14941 gtccttgagg tctgcaatct ctttctgatg gcgttcgtag gctgcctcta gctgagattt
    15001 cttcatagca taaacttctt ggaactggta gtagtcacca gagtaacgcg tcagctgttg
    15061 attttccaca tgatagacaa tattgataac gtcattgagg aatggaatat cgtgcgaaat
    15121 gagaacaaag gcattctcat agttttggag atagcgcttg agccaatcaa tatgctcagc
    15181 atccaagtag ttggtcggct cgtccaacag caaaatatca ggcttttcaa ggagaagttt
    15241 tgccaaaagc accttggttc tttgcccacc tgacaaagaa gttacatccg tatccatgcc
    15301 aaagtccata acaccaagag cacgcgctac ttcgtcaatc ttagcatcca aggtatagaa
    15361 atcacgactc tccagacggt cttgaagttc tcctacttct tccatgagag catcaacatc
    15421 cgcgccgtct tcagccattt tcatatagag gtcattgata cgagcttcag ctttgaaaag
    15481 ctcatcaaaa gccgtacgga gaacatcacg caccgactgt ctttcagcaa ggacagagtg
    15541 ctgatccaag taaccagccg tcacatattt ggaccactca acctttcctt catctggcag
    15601 cattttacca gtcacgatac tcataaaggt tgattttcct tcaccattgg caccgaccag
    15661 gccgatatgt tctcccttga ggagacggaa ggacacatct tcaaaaattg cacggtcacc
    15721 aaaaccgtga ctcagatttt taacttctaa aatactcatt ttaattcctt atcttgtttt
    15781 tatgtaatcg tttataaagg agccaagcca gatagccacc caaagtgttg gtccacaaat
    15841 catcaatctc aaagacacga ttgaaatcaa agaaaaagtc caagattaat tgcgtacact
    15901 cgattccaag actcacaaga aaactaaaaa gaaggacctt ttttgttttc cgcaaatttg
    15961 gaaatagata aaggagttgg aaaatcagag gaaaaaacaa gaagacattg aggatatttt
    16021 gtaaaaaaat ccaacataat tgtccaatgt cactcacttc gcccagtttc cagagagaat
    16081 tgaaaggagt caaaagaaaa accaggcgtc caagatgctg aatatctgga gttcccactc
    16141 ccacggtaga ttgttcttga ggagtaaagc aaaaacagac aatgcaaatg ctatagaaaa
    16201 tgactcccca gaccaaaata tgattataag tcttcttcat cattaaggat ttaccgctgc
    16261 gactgccttc tggcggtcac gtttcattgt gttagagcgc aattgtccac aagctgcgtc
    16321 aatatctgta ccatgctctt gacgaaccac acagttgacc ccttttttct taagcgtatc
    16381 atagaaagcc aacacgcgct ctttgggact acggctatat tggtcatgct cactaactgg
    16441 gttataagga atcaagttta cataagacaa tttcttgatg ttcttgagca attcagccaa
    16501 ttccaaggct tgttctacac cgtcgttgac ttcattaagc atgatatatt caaaggttac
    16561 acgacggttt gttgtctcaa tgtagtattc aatagcagca aagagttttt caatcggaaa
    16621 ggcacggtta attttcatga tacttgaacg aagttcattg ttgggtgcgt gaagagacac
    16681 ggcaagattg acctgaaccc cttcatcagc aaagtcacga attttatgag ccaaacctga
    16741 ggttgaaacc atgatgtgac gagcaccgat agccattcct ttatcatcat tgatagtacg
    16801 aaagaaattc aaaacattgt tgtaattatc aaagggctca ccaattccca tgacaacgat
    16861 atggctgacg cgttcatcct gaccacgctc atcaaagtat ttctgaacca gcatgatttg
    16921 cgctacgatt tcaccgttat tgaggtcacg ctgcttctta atcaaaccag aggcacagaa
    16981 ggtacaaccg atattacagc cgacctgagt ggtcacacag acagataaac catagtgttg
    17041 acgcatgagt acagtctcaa ttaacatacc gtcgggcaat tcaaagagat atttgactgt
    17101 accatcagca gactcttgca caatacgttg tttcaaggga ttgaccacaa actggtcatt
    17161 gagcttagca atcaaatcct tggaaaggtt ggtcatttct tcaaatgact gcacacgttt
    17221 acggtagagc cattcccaga tttgatctgt acggaatttc ttttctccct gctccaatac
    17281 ccattcctgc atggtttgat gtgccaaact atgaattgag ggtttcattt cttctcctta
    17341 ttctctactc acttctgacg aatgacaaaa tgacgttgtc ccttgtcctc tttctgagaa
    17401 tgctggtctt tctgacgacg tctatttttc ttatctgcat tcgactttcg tttagtttga
    17461 gtcggtttct ttccttttct agaaggtgtt tcttcttccg tcttacgcat tttcttgtca
    17521 aatgatgctc gcttaggggc ttcattttct aagacaaaat aggcacaacc ataactacaa
    17581 tactctaaaa ggtagtcttg taaacgactg attttttcaa gtttttcttc tgttcggtca
    17641 tccttgtaaa aacctcgtag gcgaagctgt tcgttgctcc agtcccccac gatataatca
    17701 aacttggtta agacttctga aaaacgctga ttaaaagtcg tcacatcaaa ggcatccttg
    17761 atattttcaa ccaaggaaaa agctatccct tccgtttcga ccttgtcccc gtgtaaatgg
    17821 aactccggac caggaaactt gttatagttg tataattcag gtgcaatttc ttttcgcata
    17881 gatatccttt ttccacgatt acttaatact ttattctacc ataatttcta gcagttagca
    17941 cgtttctcat aaaaatgaaa aaagtctgac gattttatca gaccagaatc ttataaccta
    18001 aaaagagaag aacaattctt ccctccaact atcattattt agcagctgcg tacaattcat
    18061 ctactttatt ccagttgatt actgaaaaga aagctttgat gtagtcagga cgcacgttgc
    18121 ggtatttcac gtagtaagca tgttcccaaa cgtccaagcc caagattggt tttttacctt
    18181 ctgagattgg tgtgtcttgg tttgctgttg aagtcacttc aagtttccct tctttgttga
    18241 caaccaacca tgcccaacct gaaccaaaac gagttgttgc tgctgcagtg aaggctgctt
    18301 ggaattcttc aaatgaacca aatgttgcat cgattgctgc tgccagttct gctgaaggag
    18361 ctgttttctc gggagtcatc aattcccaga aaagagcgtg gttcaagtgt ccgccaccat
    18421 tgttgataag tgcttgacgg atatcagctg ggatagattc tacatcagca agcaaggctt
    18481 caaggtcttc accgatttca gggtgttttt ctaaagctgc attggcattg ttgacataag
    18541 tttgatggtg tttgtcatgg tgcaaatgca ttgtttccgc atcgatgtat ggttccaaag
    18601 cgtcgtatgc atatggaagt tctggtaaga taatagccat ctgtaatacc tctttttctt
    18661 tctatatgaa aatgataacg caaacattca cttttttcaa gttttttgct tatagataag
    18721 gaaatcactg acatactttc taataaaata agcaaatcag caagaaaccc acgacaagat
    18781 aatcctgacg cgggttgtag tttcaacaaa tgtcaattga cctgactagc aatctgtaag
    18841 agtgcctttt caaaaaggaa acctttttca taaagacctg tcttaatctg atagtctgtc
    18901 tcaatcaaat aggaaatagc ttgcttcaga aagctcaaag aaagtcctct cgaatctctt
    18961 aatgcaaact tgatttgata aggatttggg ttacgtccca gataactacc taaactactt
    19021 gcaatctgcg attctgtttg gccagactcc gccaaaatct tcacctgagt aaaagtccga
    19081 aattgtccca gcatgactgc aatcagtttg atttcatctt ccccttgcaa ggtcaagtct
    19141 ctcaccaaat cgcgcgcctg atccatcttt ttagtcagaa taaactgagt taaatcaaaa
    19201 atattgtcct gcaaggtctt gggaattgcg ttaacaatat cctcttcctc gataacagaa
    19261 tccgccttat aggactgtaa aaagagaaga tttttctgga tttcgctaaa ttgaaacccc
    19321 gacttgatga ggagattttc aaaagaatga ttggtaaact gcagaccttg tttctgactc
    19381 cacttttgga agtactggcg caattcttgt tcttttactt ctactgcatc gaaggccttg
    19441 gcatcacgct taagtaattt gactaaccgt cttttgctat ccagctttcc ttctgcaaag
    19501 attatcaact tggttgttgg agaaggattg tcaaggtatt cctcaaatga cttaagctca
    19561 tcatctgtca aaaagcgttt cttagcagtc gtgatatcca taaaataatc taatatcacg
    19621 attttctcat ccgcaaagaa aggaaggctg accaactcca gttccacatc cttgtaaact
    19681 acttctttca tatcaaagta ggcaaagttg aggtcagcag aatcataccc aatctgtttc
    19741 aacacttgac tcttcatcac ttcaaactga ccctgatctg tccctgtaaa taggctcagg
    19801 ctcggtaaat ttgataaagt caacttctga ctttcttcaa tggctagcat cgtctctcct
    19861 ttcttcagat ttttcgattt aatttagtca atatagcgca atttcccacg gaaatcttct
    19921 aagctctcgt agcctttttc caccatgatt gctttcagtt cattggtaat gcggtcaaaa
    19981 gcactgacgc cttctttgtg aagggtcgtt cccacctgca ccatacttgc tccacagagg
    20041 atgtgttcaa aggcatctcg accagtcaga acgccacctg ttccgataat ttggatttga
    20101 ggatttaaac gttgataaaa ggcgtgaaca ttggctagag cagtcggttt gatgtattct
    20161 ccaccaattc caccaaaacc attcttaggc cgaataacga cagattcgtc ttctatatag
    20221 aggccgtttc cgatagagtt aacgcagttg acaaacttga gcggatattt gttgaaaata
    20281 gctgccgctt gatcaaagtg aacaatatca aaataaggtg gcaatttaat tccaagaggt
    20341 ttggtgaagt aagcaaacac ttctgccaaa atccggtctg ttgtctcaaa atcataggca
    20401 atctgaggtt tacctggaac atttggacag gaaagattta gctcagtcag accacgaaaa
    20461 tcactctctt ggactttttt caaaatagta tgggtttcct ctggagacat gccgaccaga
    20521 gataagaaga aagttcggtt cgactctttt tcctgcaaat ctaaaagata atccaaataa
    20581 tagtctaagc cattatttgg caagcccata gagttgatgg aaccaagtgg aacatcttgg
    20641 tagcgtggct caggattccc ctgacggaag tccaaggtcg ctgtcttagt aacaaaggtt
    20701 cctgccgctg agtttttgac ctcttctaac tcctctatcg tcatacaagc cacacctgct
    20761 gcattcatca agcaattgtc aaactcaaaa ccagcaattt gtgttttcgt tgataccatg
    20821 attctaatcc tccagatttc ttttattgct aatattatac cataatttta attctaggtt
    20881 tacta
//
LOCUS       DAVFJR010000036        20737 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVFJR010000036 DAVFJR010000000
VERSION     DAVFJR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.037"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(510..2237)
                     /gene="ezrA"
                     /locus_tag="VU722_001652"
     CDS             complement(510..2237)
                     /gene="ezrA"
                     /locus_tag="VU722_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU1772585.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVEEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2319..4265)
                     /gene="gyrB"
                     /locus_tag="VU722_001653"
     CDS             complement(2319..4265)
                     /gene="gyrB"
                     /locus_tag="VU722_001653"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU1772586.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSESRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4280..4843)
                     /locus_tag="VU722_001654"
     CDS             complement(4280..4843)
                     /locus_tag="VU722_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1772587.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNKGGHHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4928..5482)
                     /locus_tag="VU722_001655"
     CDS             complement(4928..5482)
                     /locus_tag="VU722_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU1772588.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLSAICAA
                     PIALNQAEILKNKRYTCYDGVQEQIFDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5493..6716)
                     /locus_tag="VU722_001656"
     CDS             complement(5493..6716)
                     /locus_tag="VU722_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU1772589.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6753..9203)
                     /locus_tag="VU722_001657"
     CDS             complement(6753..9203)
                     /locus_tag="VU722_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU1772590.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDYYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEEIYRNQSILTSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPHNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9403..10332)
                     /locus_tag="VU722_001658"
     CDS             complement(9403..10332)
                     /locus_tag="VU722_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1772591.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10472..10759
                     /locus_tag="VU722_001659"
     CDS             10472..10759
                     /locus_tag="VU722_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU1772592.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10793..12127)
                     /gene="ciaH"
                     /locus_tag="VU722_001660"
     CDS             complement(10793..12127)
                     /gene="ciaH"
                     /locus_tag="VU722_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU1772593.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12117..12791)
                     /gene="ciaR"
                     /locus_tag="VU722_001661"
     CDS             complement(12117..12791)
                     /gene="ciaR"
                     /locus_tag="VU722_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU1772594.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12900..15446)
                     /locus_tag="VU722_001662"
     CDS             complement(12900..15446)
                     /locus_tag="VU722_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU1772595.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEITARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15569..16009)
                     /locus_tag="VU722_001663"
     CDS             complement(15569..16009)
                     /locus_tag="VU722_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU1772596.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15984..16853)
                     /locus_tag="VU722_001664"
     CDS             complement(15984..16853)
                     /locus_tag="VU722_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU1772597.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTKVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16831..17331)
                     /locus_tag="VU722_001665"
     CDS             complement(16831..17331)
                     /locus_tag="VU722_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1772598.1"
                     /translation="MEIKKHFGVYAVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17342..18040)
                     /locus_tag="VU722_001666"
     CDS             complement(17342..18040)
                     /locus_tag="VU722_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU1772599.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18033..18299)
                     /locus_tag="VU722_001667"
     CDS             complement(18033..18299)
                     /locus_tag="VU722_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU1772600.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18367..19293)
                     /locus_tag="VU722_001668"
     CDS             complement(18367..19293)
                     /locus_tag="VU722_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU1772601.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19368..20183)
                     /locus_tag="VU722_001669"
     CDS             complement(19368..20183)
                     /locus_tag="VU722_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772602.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWENFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILILAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRWCLVQDSPKMKIGTYI
                     VVGILVLLVVMGYVGIGSFVQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20187..20507)
                     /locus_tag="VU722_001670"
     CDS             complement(20187..20507)
                     /locus_tag="VU722_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU1772603.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20597..>20737)
                     /locus_tag="VU722_001671"
     CDS             complement(20597..>20737)
                     /locus_tag="VU722_001671"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772604.1"
                     /translation="VFEVVDETDEVSSKHCFEVVDETDEVSNHTYGRATLTWFEEIFE
                     EY"
BASE COUNT         6248 a         4545 c         3677 g         6267 t
ORIGIN      
        1 atgtcttcca aacgaggaaa ctctcgtaaa caaagaggtt ttagaggcct atttaccgtg
       61 gactaaagtt gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatccgtga
      121 gttctctaat ctgaagattt ttcaatagac ttcgttattg gacggttacc aagttactca
      181 aagtacagat ttgaagctgc agataagact gacgaaatca ctttaatact aaatgaaaat
      241 caaaaagcaa actaagaagc tagcctcagg ctgctcaaag tacagctttg aggttgcaga
      301 taaaactgac gaagtcagta acatacgcac ggtaaggcga cgctgacgtg atttgaagag
      361 attttcgaag agtataaaac actgttttga ggtggtggat aaatcggctg ggcaaaaact
      421 caatctcagg agaaaatgaa gtaaatctcc ccacaactat agaaaaagat ttgattctgc
      481 tcctcacaca ataaaatctt tttcttttat taaaaacgaa tcgtttcacg tgttttctca
      541 tatgaggtaa caaagcgatt ggttacacca ggctcttcca cttccaatgc ttgagaaatc
      601 ttgtcaaatg aagcgtgata atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat
      661 gcttcttgaa tgcgttcatc aaatgagcga tagcggttag aatattgcaa gagttgctct
      721 gtcaaagttg catattgtac aatattataa gtttccgttt ctaaagcttc catatcattc
      781 gttgcaattt caagaactcg ggtaacagat tcaatgttaa tcattttttg ttctaactca
      841 accattaaat cctcggtatt attgcttgcc gtaaagaata acttcaagaa agtttgtgga
      901 atacctggca gattgcgttt ttccatgtat cgcttgatag tatggagacg attgacataa
      961 acattggcct tttgacgtgc attaatatca tctttctcaa tttgtgtcag gcgctcacta
     1021 actgaaattt gctcatcttc aatatctttt agttgagttt gtaaatcctc aagattttct
     1081 tcaagaactg aataagcttg ggttggttct tcttgatttg aagttacctc aacaatggct
     1141 gcctcaaaac tctctaattc tgtctgaata cgacgaacat ggcttgcagc tgtctcagga
     1201 agtaaatagg tcttgttcaa acgtgcaata tcttctccca ataaagtatt attctctttc
     1261 atatgttgaa ggtaagttgg aagagttgca agtagatttt ccactacttt ctgagcagca
     1321 atttctcgag taaaaatatc atacaaggca ttgatttcct cttgtgcctg tccattctca
     1381 tattcggcat tatccaattc caactgacga atattctctt ggtttttctt gaatgcttca
     1441 taaagcaagt ggaaacgcgc ttcaatatcc gtttcaacaa aatgataatt agcatcaatt
     1501 agtttacgat aaccggcttc caaatcctgt aattgatctg gcaattctgt agaaagcgtc
     1561 gtaaccaagg ctggaacacg atccacaata tgacttaagg ccaaaatgtg attttctgta
     1621 ttatccaaaa tcactgcggc ttccacaggg tcacccgatg aattcaaggt tacaaattgt
     1681 gaaaattcag attggatatt ttctaattgt ttttcaattt catccaaggc ttgaccatac
     1741 tgttctgaat tttcagcaac tctatgctga agttcctcaa ataaatccaa agcatgaaga
     1801 acacgaccac tatttttaga ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc
     1861 gcaatatctt cttcaatcaa agtaatttga ctctcaattt ggtcaatttg atgactggcc
     1921 ttgagaaaac gaaatgaatg gttatagcct tctgcttcaa agagattatt ttcaatatcg
     1981 gcaaaagagt tgagagataa atcgacccat ttttgattcc attcacggaa agccacttga
     2041 ctttgtccaa tcaagtgcat attttttaca gcttctactt catcatttac tggaagattg
     2101 tatagttctt cttttctttc ttctagcgcc tctaatctcc cctcgtttcg cttacgtaga
     2161 aagattgcca ctacataagc cagaactaaa atgactgcaa ttgcaaccat taaataaatt
     2221 agttgtccat tagacatatc aaactccttt tttacttgaa acaatcgtaa cgattatatc
     2281 atatttttta gaccaaggga actacttctc cctatttttt agacatcaag tgtactatag
     2341 acagcatttt cttcgataaa ctcacgacga ggctctactc gatcccccat caacatatca
     2401 aagattttat ctgcttctgc agcatcatct acagaaactc tagccatcaa gcgatgttcg
     2461 ggatccatgg ttgtttccca cagctgatga tcgtccattt cacctagccc cttataacgc
     2521 tgaatagtcg gtttggtacg actttcacta taacgggcta aagcttcttg gagtttgatt
     2581 tcttgatctg cacccggctg gatatattct ttaatctcgc ttccaacctt gacaccatag
     2641 attggtggct gggcaatata aacataacca gcttctagga ttggtttcat ataacgataa
     2701 atcaaggtta aaagaagggt acgaatgtgg gctccatcga catcggcatc ggtcatcaaa
     2761 acgagttttt ggtaacgggc tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg
     2821 gctgtgaaaa gactacgaat ttcttcgtta gctagaatct tatccatact tgctttttca
     2881 acgttcaaaa tcttaccgcg aattggaagg atagcctgaa actcacggtt acgaccagat
     2941 ttggctgatc caccagctga gtctccttcg acgatgaaga gttctgtttc agcagggtta
     3001 ttagaagaac agtctgctag tttccctgga aggttggaaa tttccaaacc agatttttta
     3061 cgtgtgactt cacgcgcacg cttggcagcc acacgagcct tggcagccaa aattcctttt
     3121 tctacgatac gtttggcaat ctgtggattt tccatgagga aatcggagaa ggcttcactg
     3181 aagaggcgat tggtaatctt gaccacttcg ctatttccca atttggtctt ggtttgtcct
     3241 tcaaactgtg gatttgggtg tttaactgag ataactgcag ttaagccttc gcgaacatct
     3301 tcccctgtta ggttgtcttc attgtctttc agtaacttat ttttacgagc ataatcgttg
     3361 ataacacgtg tcaaggctgt acggaaacct tgttcatgcg ttccaccttc atgtgtatga
     3421 atattattgg cgaaactcat gacattttca tggtaacccg ttgtgtactg catggctacc
     3481 tcaactgtga tatcatccat ctcaccgtct gtatagattg gtgtatcaaa gattacatcc
     3541 ttgttctcgt tgatatattc aacgtaactg gcaatcccac cttcataatg ataatgcttg
     3601 gtttgttcca aaccttcacg cttatctgta attgaaattt gaagaccgcg atttagaaag
     3661 gccaactctt gaatccgttt atttaattta tcaaaatcaa agattgttgt ttcagtgaag
     3721 atttttgggt ccggtgtgaa gtgaacagtt gttcctgttt tatccgtatc tccaactatt
     3781 tcaagatctg cgacaacatg accacgacgg tattcttggt aatgaatctt accatttttg
     3841 tgaacatgaa cgtctaattg agttgaaagg gcattaacaa ctgacgaccc caccccgtga
     3901 agaccacctg aaaccttgta tccaccaccg ccgaactttc ctccagcgtg aaggactgta
     3961 aagacggtct caacagcagg acggcctgtt ttttcctgaa tatcgactgg gataccacgc
     4021 ccatcatcca caacagtaat cgaatcatct ggctcaataa aaacttgaat atggctggca
     4081 aatcctgcca aggcctcgtc aattgagtta tcaacaattt cccagactag atggtgaaga
     4141 ccttcttttg aggttgatcc aatgtacatc cctggacgca tacgaacagc ctctaagccc
     4201 tctaaaactt gaatttgact ggcatcataa tcctgtgcct gcagattttt gatttcttct
     4261 gtcatcttat tcctttttct tatatgtcta atacttgtct taaattcacg atactggtaa
     4321 acaagtgggt atcaagtcct gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa
     4381 tgacaagacc agagctaatc tgatactttt ctcttaaata aagcatggat tcgggattcg
     4441 gctttctctt aaagcctgag ctagaagtca ccacttctgt aaaataagct gctatagagg
     4501 ttttttctaa aatttccaaa acctgatcat ttcgatgaga gaccaaaaaa tgatggccac
     4561 ctttatttga aatgtcttcc aataggtcag aaactccttc aaataaaatc gggtgttcaa
     4621 gctctctggc ttcattttcc ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg
     4681 tctcaatcgc aaaaggagta gaaaccttta aagcttgata gacactgtca tggtcttgtg
     4741 tgataccata cagtgccaat gtttcaacaa atgcagctgt tgaagtttca taattatcca
     4801 gtaaagttcc acctaaatcc cagatgtaat cgtgatattt catacccttc attatagcat
     4861 ttttttatga aaaaagcgat gatttccctg agttttccac ataaaaaacg agagaataac
     4921 tcccgtttta ctgattttta ccaaagacat ctcgatagag cattcctgtt cgtaaactct
     4981 ctgcgtcccc tcctagttgc tccaccaact cgtaggcaaa ggcaagggct gttgaaggac
     5041 cccgactggt tgtcaactga ccatctacca ctactgtttc cttgacgtag tgaccatcaa
     5101 agatttgctc ttgaacgccg tcataacaag tgtatcgctt atttttcaat atctctgctt
     5161 gattgagggc aattggtgcc gcacaaatgg ctgatagttt cttcccttct tgctcgaagc
     5221 tttgcaattc ttgaatcaag gtctgattat cacgtaaatg tgcagaacca ggcatacctc
     5281 caggaagaac aatcatatca tagtctgata aatctccatc aaagacatga tctgctctta
     5341 cttggattgc atgcgaaccc gttacttgct cttcaaaacc aaccatatca catgtgatat
     5401 tggctcgacg caagacatct acaactgtca aggcttcaat ttcttcaaag ccctgagcta
     5461 acataacggc tacttttacc atgattttct ccttatttaa tttgttttaa tacaaccttt
     5521 ttccgtttga atgggacttt tccgctcttt tcttcagcta aattagtctg gtaactcatc
     5581 gataaaagca aaccaacacc aatcaaatta ctgataatag ctgatccccc ttgcgaaatg
     5641 aaaggcaagg gaatccccgt caaaggaagt agtccagtca cagcaccgat attctcaaag
     5701 atgtggaaga gcaacatcat aatcaaacct gtggaaatat aagtgtagaa ctggttattt
     5761 gatttaagag taatcttcaa catacggtaa atcaacatga gatagagggc aataaccagg
     5821 acagagccaa taaagccaaa atcttctgca ataaccgtaa aaatcatatc tgactctcga
     5881 actgggataa gcagattcga agcattaaat ccctgaccaa ataagccacc actcccaatg
     5941 gcaatctgcc cttgagcctg ctggtaagtc gttgtttggg caaactcaaa gggattgagc
     6001 caagccaaaa tccgattaat ttggtaggtc ggcattccaa tttggtgaag aaaagctcgt
     6061 ccgtccttgc taataaagat agctaagaaa ccagcaactc ctgttacagc agtcacaaat
     6121 actgggataa taattttcca agaaacccct gataataaaa cgattcctga gaaaatggct
     6181 acaaaaacca aagccgtccc caagtcactt tgaagtgcta aaagaactag gactggaatg
     6241 gtaaagagaa tcatccagaa aattaacaaa aagtccagcg gaaccgtgcg tctccattcc
     6301 ttatgtttct ttgtaaattg gacaatgaca cgagccaaca tgaggatata ggatatcttc
     6361 ataaattctg acggttgaaa tagggtaatt ccatttattg atacccagtt tttggcaccc
     6421 gttgatgcaa ctaagcttgg attataaaat acaatcggca agatcataag tcccaagcct
     6481 aaaatatata gaaagggggt caccttccaa agaaattctg tattaaagag catgaccaca
     6541 aaaccaatca caagccccaa ggcaatccag gcgacctgct gccctaaaat gggcagaata
     6601 ttattgggat aatcatgact aacggctata tagatagcca ccacaccgat gaccagtaga
     6661 aaaaatactg gcaagagcaa actataatcg actctagagt cgagagaacg tttcatatat
     6721 actaacctta tactttcata caatactatt tatcaaagtt cattaaaaaa tctatcaata
     6781 gcctcgtcaa cttcggatcg agagatggtt ttaacagtcg cttcttctgc tagagatgct
     6841 actatttgtt tgccatatcg ttttccgacg attctcctat ccaaaataag agttaaggaa
     6901 cgttggtatt cacgtctcat acttcttccc aaagcctgtt ttaaacgaat aatggccatt
     6961 ggcaattgat aatcataaaa ggcatttttc ccttcttgat tcagttcttg attaatcttt
     7021 ttcgtcaagg gttcttgagg attttggaaa ggaagcctcg gtacaacttg aatcacaaaa
     7081 ggatggcttg aaaaatcaac tccctcccag aaacttgctg caccaagcaa gatttgttgt
     7141 tcaccttttt caaagcgttt ctttagctga tgaacatccc catttttata ctgggccaag
     7201 tggctaactg taagtaaatc cgatactgct agaagcatgt ctttagcggt aaagagaacc
     7261 aaaatcggtt gctggaaagc ttgaatttcc actagtaaag cagctacctc tctggcatag
     7321 acttctaagg aggtttctgt taccagaggg aaatctttga ccatgaccac ttcttgttcc
     7381 tgttttcccc gagattcaat cttgacaaat ttggcttcag gatagcctaa aaggtctgcc
     7441 aaagaaaccc tctgactaat ctcaagagta gccgatactc ccaagacttg gcaactctca
     7501 ggaagtaaag aggacagaag agtacggcct gattttgtag aagaaatctg aattttcttt
     7561 tgactcgttt cagttacttc aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc
     7621 tcatcaaagc cttctacttc taattctgaa aaatactgat ggagattgtc cagagaatct
     7681 aagatatttt tcctagattt accagactga aattgttcta tcaagtagag acactcaaag
     7741 cgaatacttt ctagtatccg ttgttgaacc ctgttttctt ctcctactaa agccttatca
     7801 attaaatcga taatagattg tatatcgtag gtctcttgaa gcagattttc tagagctaac
     7861 aaaatctttt ggacttcatc aataatcagt aaacggtcac tgacaaattc aggattatct
     7921 tcaagtctgg ttacgagata ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt
     7981 tcttgactac gtttccaaaa atcttccgtc acaaataagc tctgggatga taaattccca
     8041 tcatgacgaa ggtctgctag aaaatgttgg taacggtaga gttgcccgat ttcatccaaa
     8101 tctcctgtct ctgtctcagt aagccagacc aagacttgca ttttaaagcg tctaaataag
     8161 cgattttcat cattttcctg caaggaatga taaaaggcat ccaacttcag ataattgtgt
     8221 ggtcccttta agctatgaat atctgtatgg aacacttcct tgagacgttt accttcttct
     8281 tccatgattt gattttgaag aatctttgtc ggaacactaa gaacaatttg tcgctctttg
     8341 gattgagata aagcgggtaa gagatagcca taggttttcc caatccctgt cggcgcttga
     8401 atcagagaga caggttcatc tttcaatagc aagccaacct ctttagcaaa actttcttgt
     8461 tcctccctca cttcaaggtt caacagagaa atatttttag aaaagtcttg agatagtttt
     8521 cgtggctcca gagaagctgc cgttttctta aaatatagac cttgaacttg gaccaagtct
     8581 ggagaagtca ggatagattg gttgcgataa atttcctcaa taaccaggta ggactcatat
     8641 aggagagcgt cagccatttc cagcaagcgt tccaagagac ctttaggaag ctgggtcatc
     8701 ttttcccgta aaaaaagaag taattctgct gtagcttggg catctgaaag ggctgtgtgt
     8761 gcgtgtttaa gaggaattcc taattctcga cacaaaatcg gcaagctata tttttccagt
     8821 tcagggaaaa agacctgggc caattcgacc gtatcaacac gagggtttct tagctcatag
     8881 ccttcaaaaa ataaattttc cgccaagaga ttagcatcaa actgaacatt atgggctaca
     8941 aaaatcccat cctccaccaa gtcaaagatt tttctggcaa cttgcgaaaa atcaggtgct
     9001 tgcgccagac gttggtctgt caatcctgtc agttctttga tatgagcatc caagggttca
     9061 tgtggattga catccgtcgt atagtaatcg acgatttctc catcctcaat cacgacaatt
     9121 cccacttgga taattttagc cttactacct gtgctagttg cctctaaatc caccacaaca
     9181 tagcgattac caatcgtttt cattataaaa aattatacca aaaaaagggc catttggcac
     9241 ctgcaaacat aggataattt tcaaactcaa gaacactact tttcttaaaa atcccatcga
     9301 atagagcatt ctagcctgct gattttttta aaatagtgaa gaaatacgaa aaattgagag
     9361 aagaaatgtt tgcatcttcc ttctctcaac gaatcatgta ttttatttaa ccatgtcagg
     9421 atcgtagtca taaaatcctg tatcaaggaa acggttttta gggtgaagtt tacgaacttc
     9481 ttcatccagc aagaaggctt ggtcatggct aaagttgccc tcttgaatca agctacgcgc
     9541 ttggataaag agttttgcaa tctcaacaaa gttctgacca ggagtgtaga gcccttctag
     9601 tttccagcga gtaaagccat gctccaccaa ttctgttaat ttgatcatca aatcaaggtc
     9661 attgttggca aagatatggg tcccatgatt atcttcaaaa atggaatagt ggctctctgg
     9721 atcacttggc tcagccaaga agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt
     9781 aaagttatag tagttttgca agagcggacg tttagaatga tggatgacac tagcaccgta
     9841 aaccaaaact tcagcaggaa tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg
     9901 aatttcacgc gccaaaacag cctcagatgc gccagccttt tgtccccaga agttaatctg
     9961 acgactgcta gttaccatgg ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg
    10021 gttgactacg taaaagacgc ctgcatcccc aatcgtaata tagtctgtct tgatttcttc
    10081 caagaagtct aagaaaggct tgatacggtc catcatatct tggtgcatga gagcattgac
    10141 cgcaacgatc aattccttac cagcatcatg aaccaactta gcgatttcac gtaattggtc
    10201 ataactaaag gtcgttggca gacgaaggcc aaaatctttc tcaccgacat agatacggtc
    10261 tacgccagct tcgagtagtt gttcaacttg ttcaatactt tcagcagttg ctgtaatgac
    10321 aatcttttcc ataagaaaaa ttataccaca tttctccaaa atcagccatg ctttgaaaat
    10381 gaaaagggac tttattcttt ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat
    10441 aaaataggta tgtactgtta aggagagaat catgcccgta agaaaattac aatcctatga
    10501 ggtagactat caagaagaat taaaccagca gcttcctcat taccaagctt atacacctga
    10561 agcgcaatct gatgccaatc tcaaggaaat cctatttttt attaatatcg ctgttttttg
    10621 tatctgtatt gctatcttta gttttatctt tttagcatta aaattatcaa ctgctcttgc
    10681 ctttgccgca gcaatcggat tcagcttact tgttttaaaa gttcaacggt ctattatcaa
    10741 acgaaaacgt agaagataaa tccaaaatat cgccccaatt ggagcgatat ttttattttt
    10801 tctttttaga tggtgtctga atggcaatct tcacttcaaa gattgttccc ttgggtttat
    10861 tatctttgac agtaacagtt ccttttagag catctacaat ttgcttggct agggataatc
    10921 ctaaaccaaa accacctttt tgccgggttc tagctttgtc tactcgataa aaacggtcaa
    10981 aaattttctt tttatcttct gtcgaaatac cgattccatt atcagaaaca agtaaataaa
    11041 gattgcgatc ggtcgccgag ataagaaaat caatttcacc atcctcctca gtatacttga
    11101 cggcattatc gaaaagaatg gtcatcagtt gtttcagaag aagctgatct gtgacaattg
    11161 ttcgatggat acgattttca aaacggaaga cacgattatt ttccgaagca atcatctcgt
    11221 agtttgtgaa agttgtatta aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc
    11281 catcatctct ccgagctaag ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt
    11341 cttccaaact cgatgcaatg ctttcgctca catccataat ggtagcttct ggcttacgaa
    11401 aaagggtctc taagcgattt tgcaaaactg cgagtggagt tcgtaactca tgactggcat
    11461 tttccacaaa agactgttgc ttctgcatac tctcaagcag gggcctaaca ctgaccctag
    11521 ctagatagag actggcaagt aaagacaaaa tccagaaact agccatcacg accacaatca
    11581 attgctcatg cttttgacta gcctgctcca actgactggt attaatcaag acagcagcat
    11641 actttatatt ggttgaaacc gaactaatat tggtctccat caaaatcaca cgatagattt
    11701 cttcctgccc atagctatta aaaacctgaa tctggtaaat atgtcctagt tctttctttt
    11761 ctaacttaat cttatccaag cccaaaaatc gatttccaga aagaagttga gtaaagtctt
    11821 tatcaaagag aatgacttcc gtattggaac tgacattagg ttttatttct actttactag
    11881 cgtccgccct agcattttct aaatctttaa tctcttctgt tgccctattt atagccagct
    11941 gaataactgc ttgaggattt tcactcagtc catgaagctt atcgtccacc gaagtataaa
    12001 gactcgaatg catgacttgt aaaataatca gagtcattgt agaaaaaatc agggtgaaga
    12061 caccgaagtt gcggataaaa taactaaagt catccgcata ccatgttttt ttaagtttac
    12121 tgaacatctt ttaaaagata cccaacacta cgcaaggttt gcaaattctc tgcaaaagtg
    12181 gttcccttta atttcttacg gacttttgaa acatagactt cgacaaccga aatcgttgta
    12241 tcactatcaa atccccatag acggtcaaaa atctgcgtct taggcaaaat cacattttga
    12301 ttttgaagga aataaactag taaatcgaac tctttcccca gcaattcgac aggagtatct
    12361 tcaactttaa cggtattggt tgataaatta accacgatat tcccataagt caaggtgttt
    12421 tcattaaact tccctgaacg tttgagaagg gcctgaatcc gcattttaag ttcttctagg
    12481 tagaaaggtt tggtcagata atcatccgct cccagttcaa atccatgtcc cttgtcatcc
    12541 aaactttcct tggcagtcat aatcagaact ggtgtcgtaa ttcccttttc acgcaattct
    12601 tttaagactt ggaaaccatt tttttctggc aacatcaaat ccagcaaaat caagtcatag
    12661 acaccactct cagcttcgta gagaccttct tctccatcaa atacctgcat aacatccgca
    12721 aaatcgtcta aaaagtcaaa tactgaattt gacagaccta ggtcatcctc aaccaataag
    12781 atttttatca tgagaaactc ctccttatta aaactattat accaaatttg ccttaaaaaa
    12841 aactcaactc tctgcatttt acatgagata gctgagtttt ctttttattt taggcttatt
    12901 tatgcatttc cgtattgaag aacaactgct tcgactgcag ctttttcacg gctaatcaag
    12961 tcaacacgtg ctgtaatttc cttgattccc ataccgatgt tacggctaag agcaaggtca
    13021 gaaagttgcg gctcaaagaa ctccttgtat tccgccaagc gttgctgagt cttaaataca
    13081 tgagcaggaa ggataacaaa gctatcaaag ctcatatctc ctccaagggc tgccttaatc
    13141 caagcccagt tttcacgcgc ccaagaccaa gctgttttct gagttgcttg atgagctagg
    13201 aattggtaat accaagcaga caagtcctgt ggtttgacca caaatttgtc cttccaagaa
    13261 gtaatcaagt tttggatatt atccgcatct gtactgtatg caagagctgc tgccaactgg
    13321 cgtttaaaga cagcatctgt tgcgtgagta taagtatcaa gataaagtgc taacaagtct
    13381 ttagtctcat gatgtttcat ctcattaatc agaacttgtg agcgaatagc tgctgggagt
    13441 cctgcaagat tctccttgtg tgttgcgaag atttggctag cgacttgact agcttctgca
    13501 tcatttgagc gaatcatcat cgaaacagcc agctgacgaa ccaattcatc ctcatctgat
    13561 tctccgtctt tagcttcaaa accaagacgg tcatagttat gacgagccaa tttagcaacc
    13621 agtcctttga aggctgtttc agcatccgtt ccttcatcaa taaagcgctc aagggctgaa
    13681 atcacttgag aaacagctga aaccaccaga taagactctt ccttagcaag tttatcaaga
    13741 actggaagca agtctgcata agaaatgtgc cctgcctcag ccaacaaacg acgttcttga
    13801 acaatttgca gtttgcttgt gttatcaagt gtctctagct cagcaagaac agcttctaac
    13861 aagtctcctt gatagtcggt aatatagtgg gcagtatttt cagtgttgag acgaagagct
    13921 ccttcatttt cagcaagaag agctgcgtag ccagggattt cgatactttc agtttcgagt
    13981 gtatcaggca agcctttcca gttgctattg aggggcacca cccagagacg gttcttgtct
    14041 tcgttctcac cgatgaagaa ttgtttttgt gaaatcttca agacatcatt ttcaactttg
    14101 acagtaagaa ctgggtaacc aggctgttcc aaccaagaat ccatgaaggc tgcgacatca
    14161 cgtcctgacg cttgaccaag ggcatcccaa aggtcactac caatggtgtt gctgtattgg
    14221 tgtttttcaa agtaggcatg caaaccttta gcaaaatcag catctcctag ccaacggcga
    14281 agcatgtgca tgagacggct tcctttggca tagacgatag cgccgtcaaa gagtgtattg
    14341 atttcatctg gatgtttaac ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt
    14401 tcaagagcaa gaggtactcc acctgtttgg aaatcttcaa agatattcca gcttggttcg
    14461 atggtatcca cacagacgta ttccatcata ttagcgaaac tttcattgag ccaaaggtca
    14521 tcccaccatt tcatagtcac gaggttccca aaccattggt gagccaattc atgggccaca
    14581 acaagggcaa cttgttgacg gctagcaaat gtagagttct catcgacaac caagtaaact
    14641 tcacggtagg tcacaagacc ccagttttcc atagcaccag ctgagaagtc aggaagggcg
    14701 atgtggagag attgaggaat tgggtactta actccatagt aatcttcgta aaactcgata
    14761 gagcgaacag cgatatccag tgagaaatca agatttgaaa gtggatgtgc tttggttgag
    14821 tagacaccta ccagggtacc atttttagtt ttagcggtca ccccttgcaa atcaccagca
    14881 acaaaggcca acaagtaaga agacatgcga ggtgttgtct caaacttcca gatacctgtt
    14941 tccttacggt tttcaacatc gatttctggc atgtttgaca aggccaattc accttctgct
    15001 tggtcaaagc gaagagagag gtcaaaagtt gctttggctt caggctcatc cacacatggg
    15061 aaagcttcgc gcgcaaaatg gctctcgaac tgagtagaca agacctcctt cttgactcca
    15121 tcaactgtat aataagaagg gtaaatccct gtcatgttgt ctgtaatttt accagaaaag
    15181 gcaagaacca attcaacttg accagcctca gccaattcga tatgaagggc ttcattgtca
    15241 tggtcaactg taaatggacg agcttgacct gcaacttcta cagaggtgat ttccaagtct
    15301 ttttggtgga gggagatgcg gtcactctgt gcttgaccag tgatggtcac tttcccagaa
    15361 aaagtcttgg tctcacgact caaatctaaa aataaatcat aatgttcagg aacaaattgc
    15421 ttaataaaat gttcaactgc ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc
    15481 tcttcttcaa acaaacttat tatatcatat tttgcctgag aaaaaaggat tggacagcga
    15541 tttccaaaac tttcttcctt ctaatagtct acagtgggta gaccttgcga aattcttcta
    15601 aaacaacctt gctttcaggt gtaaaagtca atcctgcttc acccaagcag tctctgaaaa
    15661 aatcctcatg aacctggcgc caatagacaa gtgtcttgtt tccctcacct tccttatagg
    15721 catggtcagc tgacactcga ttgaagggtt taacagaaac ctttgtaatt tcgacaatgc
    15781 agacagactg attttgacta tctaaaatga catcgaaggt ccctacttgg ggaagtggtt
    15841 cgtcttctag tacatagagg tcataggctg atgctgttgc tgtcttttct cctttaaaca
    15901 ccaaatccgc taaaaggtct ggttcaactc caaaagccca agcatcgatt tcatctccga
    15961 tcaaaggatt gatttgcttg tatttattcc acatttcttg cggtatcatg ggtactcctt
    16021 tgtaattttt tactttcttc ttttatgtgt ttaagatgat ctggatggtc aatctctaaa
    16081 tcaaaaatct ctggaataga actgtagtgg ataatgcact tgatacccaa ctgattcatt
    16141 ttttgtatga aagaagtatt cagatagcct gctacagcaa aattaatctt gttctttctt
    16201 gctttatcct gcatatctct tagcatatct aacattattg gactttccat atcatgccat
    16261 tgactgtttc tcatagtcgc aaaaacaaag gaagtcaaat cattcattcc aactacaatc
    16321 tttgaaatgc ccgtttccag tatactagat aagtcaaaat acgctgacgg taattcaatc
    16381 atcgttccga ctttcccagt aaagccatac tgacgcaata ctgtaatagc ttgttttaat
    16441 tggtcggcat cattgacaaa aggaaagata agagatagat tgggattggt ttgataaact
    16501 tttgtaacga catgtgcttc agcctgaaat tcatccaaac acgccagtaa acgcctggtt
    16561 cctctatagc caaacaaggg atgcccttcg tcaaaaaact ctctagtccc cactaaacaa
    16621 ttggcctctg tattcgttaa ttcagaaaaa cgataccaaa cttcttcatc tgagtacagg
    16681 gagcagatag tctctagata atcttttaca aattgctgac aacttgctaa tatgatgttt
    16741 tgattaagct ctctcaacaa atattcccca cgaatcatgc cgacgtggtg aaatagttga
    16801 ggataaattt tttcaagaat tttttcgcca ctaagggcaa gttgatttct catcattcac
    16861 cttccaattc atgtaagaag tcttgtccag ttctggaaat cctaataatt cagacttaac
    16921 cttcaagact aatggcgatg cattttcttc tgtaatttct tgaatatcca tccaaatata
    16981 tccaagtgaa tcattcgcac catcagacac agcttccgaa gtcgtaactt gaggtgcact
    17041 ctcattcatt tcaacatcat acaaggccat gacatggtga accataaaat tttttaactc
    17101 ttctctgacg aaaacatcgt agattcgagg attagagtag cttctaacag taaatctcgt
    17161 ctcttccata acttctctag tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc
    17221 tccaggtaga tcataccgat gttgataagg gcctctcgtt ttttcaatgc aaagtaactt
    17281 tccattttca aagcaaacag cgtagactcc aaagtgtttt ttgatttcca tccaactcct
    17341 cctacttcaa agaccagcca ccatctattg tcaagatttg tccttgcatg gcgctcgctt
    17401 ttccacttgc taaaaaaaga ctaagctctg ctatttcctc tggctcaatc cagcgcttga
    17461 ttggggtttc actagccacc cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca
    17521 tagctgtctt gactgctcct ggagcgatac caaagacctg aatcccagct tcagcatagt
    17581 ctagagccaa ctgcttggtg aagccagcca aggcatgctt ggatgaagta taggcgtgac
    17641 cacctccacc tgctaggcta gaagcaatgg aacacatatt gatgatgatt ccctttttat
    17701 tttccagcat ttgtgtcaaa taataccgag tcaactctac tggaataatg tagttgattt
    17761 caaaaatctc ttgaatgtcc tgcgccgttt gttccaacag tggtttgtaa tcatccaaaa
    17821 ctccagcagt attacacaaa acatccacct gagggcacca gtcaaaaata ggttccaagt
    17881 ccaaggtcaa atctctctgt aaaaagtgaa aatcaccctc taagagtggc ttttcacctt
    17941 ggtcaactcc ataaacttga tagcccttct ctaaaaagag gcgagcttga gccaatccga
    18001 tccctgaact cactcctgta atgagtacac gtttagtcat gcacttctac ccaatccgtt
    18061 gccaaaacat cacaaactgt cgggctccac atggaaaaac cttctccttc gccagaaacg
    18121 ttgattagga aataaggtgt catttcaagt gcaagcccat tttgctcgat ggtatcaaag
    18181 agttggacat agttttccgc acctccccaa ccagttcgta catattttct cttagccttt
    18241 aacccaggca ggatctcttc aaatgtcatg tttttctcct ttaattctac attcttcatt
    18301 taattataac aaaaaaaccg ctttaaaacg gctttttgac tgtgatttat ttacatcttc
    18361 ttctacttac ggcaaattat tccctgcagc aagataaatt tcataccatt cttttcttgt
    18421 taagctaaag tttgccgctt ggctaacttc tctcaagtgc ttaggatttg tggtacctac
    18481 aactgcctgc atttttgctg gataacgcaa tatccaagaa atggcaatag ttgaagaggt
    18541 tactccatat ttaatagcta aacgatcaag tacttgattt aaagcttgaa atttctcatt
    18601 tccaacaaaa ttccctttaa aatacccgaa ttgcaagaca gaccatgctt gaatgaccac
    18661 atcgtgtaat tggcaatatt caaaaatgct gccatctcgc atagctgctt gactatcttc
    18721 catattaaca tgaaaagctg attcaaatcc tggagtaaaa gccgcactca attgtagctg
    18781 attaacagct aacggctgct tgacatcttt tttaagcaac tccatcatca taggattttg
    18841 attagaaact ccaaaatctc gaactttacc ttgtttataa aggagattaa aggcttctgc
    18901 tacttggtca gattccatca aagcatctgg tcgatgaagg agcaagctat ctagatgatc
    18961 aatcttcaat ctttgcaaaa taccgtctac tgattttata atatagtcct tagaaaaatc
    19021 aaaataggta aattcttcaa tgcgaatgcc acatttggac tgaatccaca tcttttctct
    19081 taaatctgga cgatttttta ggacaagacc taacagttct tcacaacgac cacgaccata
    19141 aatatcagcc aagtcgaagg cattgattcc aacagaaagt gctgtttcta caagctcttc
    19201 aacttctttt acagacttat cttttattct catcattccg agaacaattt ctgataattc
    19261 tttgtcatct tgaccaagag ttatgtatct catcaaattt ttctccttta atttctaaca
    19321 ttcttccctt cattataaca aaaaaccgct ttgcaacggc tttttgacta tacttcactc
    19381 cattttatct tcttaaaccc acggaacaag acaaagattc caataaagag gacagctaaa
    19441 ggaataactt ttgtaaggaa aacatttgaa attcccatcc actcataata acggagcaga
    19501 gaacccacca caagatgggc aataatcata ctgacaaatg gacgaaagac cgcttctttc
    19561 caattccaaa taccgataac tagcgaaatc gtaaagacag acaaactatc ccagggagcc
    19621 ggaatataaa aggctccttc ttgtacaaaa cttcctattc ctacatatcc cataacaact
    19681 agcagaacaa gaatcccaac gacaatatag gtgccaattt tcattttagg agaatcttgg
    19741 actaagcacc aacgtaagat tgtggccaca agtccaaatc caatcagaaa aataagaagt
    19801 tgccctaaaa atgtgagcaa attgactgtt aagagaggac ctttagaaaa atcacttagt
    19861 agttgataat aacgtaatac cgctaggata agaattggcg tcaaaaggga ctctttgata
    19921 gaactgcgag gtgctccctt gagaatctct ttcattattt ttttaggatt cttacctaga
    19981 taatcctctg cactcatgcc atctcgttct gcttctgaga aatctagcat catcaaatag
    20041 atctgctctc tgagatagtc ttcatcatag agaaatccag caagattaaa attttcccac
    20101 aactcctcaa aatacttttg attctcctca gaaaactcat gtagcaaagc gcttgtttct
    20161 tcgtaatact tcattttctt catggtttaa cccccattct taatcccttc tactttttga
    20221 ctcaaatcgt cccattgttg ccaaaagact gagacacgct cttctccttc tttcattaat
    20281 gaaaaatact tccgatctgg accatctggc gacgggcgca tgtcgcctct tatccattga
    20341 tttttttcta acttttgcaa caaaggataa atagttcctg gaacgatagt atcaaatcca
    20401 gcctctcgca aagtctgaac caactcataa ccataccgct ctttttgacc aatcatatcc
    20461 aagacacaac cttcaagaac accttttaat agctgagttt ctttcatcac ttctcccttc
    20521 taatctattt tgtaatacct actagtaact tcacctatag tatatcactt ctacactagt
    20581 ttgtaaagca taatagttaa tactcttcga aaatctcttc aaaccacgtc agcgtcgccc
    20641 taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa caatgttttg
    20701 agctgacttc gtcagtttca tctacaacct caaaaac
//
LOCUS       DAVFJR010000037        20124 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVFJR010000037 DAVFJR010000000
VERSION     DAVFJR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.038"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            137..571
                     /locus_tag="VU722_001672"
     CDS             137..571
                     /locus_tag="VU722_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1772605.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            571..1545
                     /locus_tag="VU722_001673"
     CDS             571..1545
                     /locus_tag="VU722_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU1772606.1"
                     /translation="MAFSKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGIIGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            1605..1829
                     /locus_tag="VU722_001674"
     CDS             1605..1829
                     /locus_tag="VU722_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU1772607.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            1948..2922
                     /gene="fabK"
                     /locus_tag="VU722_001675"
     CDS             1948..2922
                     /gene="fabK"
                     /locus_tag="VU722_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU1772608.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            2915..3835
                     /gene="fabD"
                     /locus_tag="VU722_001676"
     CDS             2915..3835
                     /gene="fabD"
                     /locus_tag="VU722_001676"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU1772609.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVSSGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            3869..4600
                     /gene="fabG"
                     /locus_tag="VU722_001677"
     CDS             3869..4600
                     /gene="fabG"
                     /locus_tag="VU722_001677"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU1772610.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGVISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            4622..5857
                     /gene="fabF"
                     /locus_tag="VU722_001678"
     CDS             4622..5857
                     /gene="fabF"
                     /locus_tag="VU722_001678"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU1772611.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            5860..6345
                     /locus_tag="VU722_001679"
     CDS             5860..6345
                     /locus_tag="VU722_001679"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU1772612.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            6342..6764
                     /gene="fabZ"
                     /locus_tag="VU722_001680"
     CDS             6342..6764
                     /gene="fabZ"
                     /locus_tag="VU722_001680"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU1772613.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            6776..8143
                     /gene="accC"
                     /locus_tag="VU722_001681"
     CDS             6776..8143
                     /gene="accC"
                     /locus_tag="VU722_001681"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU1772614.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKTEDLVFAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAESVGYENAGTIEF
                     LLDEASGNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQIRIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            8180..9046
                     /locus_tag="VU722_001682"
     CDS             8180..9046
                     /locus_tag="VU722_001682"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU1772615.1"
                     /translation="MALFSKKDKYIRINPNRSIREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLVLTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     TMREKTGLDEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEQL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            9043..9810
                     /locus_tag="VU722_001683"
     CDS             9043..9810
                     /locus_tag="VU722_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU1772616.1"
                     /translation="MNIAKIVREAREQSHLTTLDFATGIFDDFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLRVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGSRAMEAAELMKITSHELLEMDVVDKVISETGLSS
                     KELIKNVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            9969..10154
                     /gene="briC"
                     /locus_tag="VU722_001684"
     CDS             9969..10154
                     /gene="briC"
                     /locus_tag="VU722_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU1772617.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            10260..10651
                     /locus_tag="VU722_001685"
                     /pseudo
     CDS             10260..10651
                     /locus_tag="VU722_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835936.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10673..10900
                     /locus_tag="VU722_001686"
     CDS             10673..10900
                     /locus_tag="VU722_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772618.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFAFVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(10949..11371)
                     /gene="nusB"
                     /locus_tag="VU722_001687"
     CDS             complement(10949..11371)
                     /gene="nusB"
                     /locus_tag="VU722_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU1772619.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVAEEQ"
     gene            complement(11364..11753)
                     /locus_tag="VU722_001688"
     CDS             complement(11364..11753)
                     /locus_tag="VU722_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1772620.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(11775..12335)
                     /gene="efp"
                     /locus_tag="VU722_001689"
     CDS             complement(11775..12335)
                     /gene="efp"
                     /locus_tag="VU722_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU1772621.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(12666..13709)
                     /locus_tag="VU722_001690"
     CDS             complement(12666..13709)
                     /locus_tag="VU722_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HEU1772622.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTCVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            complement(13833..15275)
                     /gene="gatB"
                     /locus_tag="VU722_001691"
     CDS             complement(13833..15275)
                     /gene="gatB"
                     /locus_tag="VU722_001691"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU1772623.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMQTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(15275..16741)
                     /gene="gatA"
                     /locus_tag="VU722_001692"
     CDS             complement(15275..16741)
                     /gene="gatA"
                     /locus_tag="VU722_001692"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU1772624.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGFPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(16741..17043)
                     /gene="gatC"
                     /locus_tag="VU722_001693"
     CDS             complement(16741..17043)
                     /gene="gatC"
                     /locus_tag="VU722_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU1772625.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            17256..18800
                     /locus_tag="VU722_001694"
     CDS             17256..18800
                     /locus_tag="VU722_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU1772626.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            19215..19412
                     /locus_tag="VU722_001695"
     CDS             19215..19412
                     /locus_tag="VU722_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU1772627.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            19523..19699
                     /locus_tag="VU722_001696"
     CDS             19523..19699
                     /locus_tag="VU722_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU1772628.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            19815..20003
                     /locus_tag="VU722_001697"
     CDS             19815..20003
                     /locus_tag="VU722_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU1772629.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
BASE COUNT         5799 a         3760 c         4668 g         5897 t
ORIGIN      
        1 agctcattcg gagagaagaa gacctaaatt tacaggaaaa taaaaaatac ttgcatcatt
       61 ctttgaattt tgatataatt ctttttgtca aatgttttga ttgtaaaagt tttttgaaga
      121 aggagggata tgaaaaatgg actaccaacg aatcaatgaa tatttaacat ctatatttaa
      181 caatgtcctt gtgattgagg aagtgaactt gagaggtagt cgttttaagg atatctccat
      241 caaagaaatg catacgattg atgttatcgg taaggctcca gacgtgactc caagtcaagt
      301 gtcaaaagag ttgatggtaa ctcttggaac tgttacgaca agtttgaaca atttagagcg
      361 taagggctac attgagcgag ttcggtcaga acaggatcgt cgtgtggtgc atctgcattt
      421 gacaaagaag ggtcgcttga ttcatagact gcataaacgc ttccacaagg ccatggtaga
      481 aaaaattatt gatggcatga gcgaggaaga aattgctgtc atgggtaaag gtttgactaa
      541 tctttaccaa tttttggagg atttgaaata atggcttttt caaaaataag ccaggttgct
      601 cattatgttc cagagcaagt ggttacaaat cacgacttgg ctcagattat ggataccaat
      661 gatgagtgga tttcaagtcg aacgggaata cgacaaaggc atatttcaag aacagaatct
      721 accagtgatt tggctacaga ggttgctaag aaactgatgg caaaagctgg aataatagga
      781 gaggaactgg attttatcat cctagctacc attactccag attcgatgat gccctctaca
      841 gctgctcgtg ttcaagctaa tattggtgct aataaagcct ttgcttttga cttaaccgca
      901 gcttgcagtg gatttgtatt tgctctttca actgctgaaa agtttatcgc ttctggtcgc
      961 tttcaaaaag gcttggtgat tggtagtgaa accctctcta aggcagtcga ttggtcggat
     1021 cgatcaacag ctgtgttgtt tggagatggt gctggtggtg tcttgttaga agctagcgag
     1081 caagagcatt tcttagctga gagtctcaat agcgatggaa gtcgcagcga gtgtttaact
     1141 tatgggcatt caggtttgca ttctccattt tcagatcaag aaagtgcaga ttcatttttg
     1201 aagatggatg gacgcacagt ctttgatttt gccattcgag atgtagccaa gtctatcaag
     1261 cagactattg atgaatctcc tatagaggtg acagacttgg attatctgct acttcatcaa
     1321 gccaatgacc gtattttgga taagatggct agaaaaattg gtgttgaccg agccaaactt
     1381 ccagccaata tgatggaata tggcaatacc agtgcagcca gtatcccgat tttactttca
     1441 gagtgtgtag aacaaggtct catcccttta gatggtagcc agactgttct tctatcaggc
     1501 ttcggtggag gcttgacctg gggcacgctc attcttacaa tttaggtaat catgtggtga
     1561 acacattgtt ataaaaaaac tatttatttt aaaggagtcc tatcatggca gtatttgaaa
     1621 aagtacaaga aattatcgtt gaagaacttg gaaaagacgc atcagaagta acacttgaat
     1681 caacttttga tgatttggac gcagattcat tggacttgtt ccaagtaatc tcagaaatcg
     1741 aagatgcttt tgatatccaa atcgaagcag aaaatgactt gaaaacagtt ggtgacttgg
     1801 ttgcttacgt tgaagagcaa gcaaaataag cagaatatta gtagaaggag tagggagaaa
     1861 cccactccct cttgtttagg taatagtttg actgtcaaat tatggtgaaa tcgaactatt
     1921 acgtaagcaa ggaaggttgg aggcactatg aaaacgcgta ttacagaatt attgaagatt
     1981 gactatccta ttttccaagg agggatggcc tgggttgctg atggtgattt ggcaggggct
     2041 gtttccaagg ctggaggatt aggaattatc ggtgggggaa atgccccgaa agaagttgtc
     2101 aaggccaata ttgataaaat caaatcattg actgataaac cctttggggt caacatcatg
     2161 ctcttatctc cctttgtgga agatatcgtg gatctcgtta ttgaagaagg tgttaaagtt
     2221 gtcacaacag gagcaggaaa tccaagcaag tatatggaac gtttccatga agctgggata
     2281 atcgttattc ctgttgttcc tagtgtcgct ttagctaaac gcatggaaaa aatcggtgca
     2341 gacgctgtta ttgcagaagg aatggaagct ggggggcata tcggtaaatt aacaaccatg
     2401 accttggtgc gacaggtagc cacagctgta tctattcctg ttattgctgc aggaggaatt
     2461 gcggatggtg aaggtgctgc ggctggcttt atgctaggtg cagaggctgt acaggtgggg
     2521 acacggtttg tagttgcaaa agagtcgaat gcccatccaa actacaagga gaaaatttta
     2581 aaagcaaggg atattgatac tacgatttca gctcagcact ttggtcatgc tgttcgtgct
     2641 attaaaaatc agttgactag agattttgaa ctggctgaaa aagatgcctt taagcaggaa
     2701 gatcctgatt tagaaatctt tgaacaaatg ggagcaggtg ccctagccaa agcagttgtt
     2761 cacggtgatg tggatggtgg ctctgtcatg gcaggtcaaa tcgcagggct tgtttctaaa
     2821 gaagaaacag ctgaagaaat cctaaaagat ttgtattacg gagccgctaa gaaaattcaa
     2881 gaagaagcct ctcgctggac aggagttgta agaaatgact aaaacagcct ttttatttgc
     2941 tggtcaaggt gcccagtatc tagggatggg acgggatttc tatgatcagt atccgattgt
     3001 taaagaaacg attgatcgag cgagtcaggt gctcggttat gatttgcgtt atctcatcga
     3061 tacggaagaa gacaaactca atcagacccg ctatacgcaa ccagccattc tagcgacttc
     3121 ggttgctatc taccgtttat tgcaagaaaa gggctatcag cctgatatgg ttgctggttt
     3181 gtctcttgga gaatactctg ccttggtgtc aagcggcgcc ttggattttg aagatgcggt
     3241 tgccttggta gctaagcgtg gagcctatat ggaagaagcg gctcctgctg actctggcaa
     3301 gatggtagca gttctcaata cgccagtaga ggtcattgaa gaagcctgtc aaaaagcttc
     3361 tgaacttgga gtggttactc cagccaacta taacacacct gcacaaatcg tcattgctgg
     3421 agaagtggtt gcagttgatc gagcggttga acttttgcaa gaagcaggtg ccaaacgctt
     3481 gattcctctt aaggtgtcag gtccctttca caccgctctc cttgaacctg ctagccagaa
     3541 actagctgaa actctagctc aggtaagttt ttcagatttt acttgtcccc tagtcggcaa
     3601 tacagaagct gctgtgatgc aaaaagagga cattgctcag ctcttgacgc gtcaggtcaa
     3661 ggaacccgtt cgtttctatg aaagtattgg ggtcatgcaa gaagcaggca taagcaactt
     3721 tatcgagatt ggaccaggga aagtcttgtc aggttttgtt aaaaaaattg atcaaactgc
     3781 tcacttagct catgtggaag atcaagcgag tttagtagca cttttagaaa aatagactaa
     3841 aataagtaga agttttgaaa ggaaaaaaat gaaactagaa cataaaaata tctttattac
     3901 aggttcgagt cgtggaattg gtcttgccat cgcccacaag tttgctcaag caggagccaa
     3961 cattgtctta aacagtcgtg gggtaatctc agaagaattg ctcgctgagt tttcaaacta
     4021 tggtatcaag gtggttccca tttcaggaga tgtatcagat tttgcagacg ctaagcgtat
     4081 gattgatcaa gctattgcag aactgggttc agtagatgtt ttggtcaaca atgcagggat
     4141 tacccaagat actcttatgc tcaagatgac agaagcagat tttgaaaaag tgctcaaggt
     4201 caatctgact ggtgccttta atatgacaca atcagtcttg aaaccgatga tgaaagccag
     4261 agaaggtgct atcattaata tgtctagtgt tgttggtttg atggggaata ttggtcaagc
     4321 taactatgct gcttctaagg ctggcttgat tggctttacc aagtctgtgg cacgcgaggt
     4381 cgctagtcgg aatatacgag tcaatgtgat tgctccagga atgattgagt ctgatatgac
     4441 agctatctta tcagataaga ttaaggaagc tacactagct cagattccga tgaaagaatt
     4501 tgggcaggca gagcaggttg cagatttgac agtattttta gcaggccaag attatctaac
     4561 tggtcaagtg attgccattg atggcggctt aagtatgtag cgaaagctag aggagaaaag
     4621 aatgaaacta aatcgagtag tggtaacagg ttatggagta acatctccaa tcggaaatac
     4681 accagaagaa ttttggaata gtttagcaac tgggaaaatc ggcattggtg gcattacaaa
     4741 atttgatcat agtgactttg atgtgcataa tgcggcagaa atccaagatt ttccgttcga
     4801 taaatacttt gtaaaaaaag ataccaaccg ttttgataac tattctttat atgccttgta
     4861 tgcagcccaa gaggctgtaa atcatgccaa tcttgatgta gaggctctta atagggatcg
     4921 ttttggtgtt atcgttgcat ctggtattgg tggaatcaag gaaattgaag atcaggtact
     4981 tcgtcttcat gaaaaaggac ccaaacgtgt caaaccaatg actcttccaa aagctttacc
     5041 aaatatggct tctgggaatg tagccatgcg ttttggtgca aacggtgttt gtaaatctat
     5101 caatactgcc tgctcttcat caaatgatgc gattggggat gccttccgct ccattaagtt
     5161 tggtttccaa gatgtgatgt tggtgggagg aacagaagct tctatcacac cttttgccat
     5221 cgctggtttc caagccttaa cagctctctc tactacagag gatccaactc gtgcttcgat
     5281 cccatttgat aaggatcgca atgggtttgt tatgggtgaa ggttcaggga tgttggttct
     5341 agaaagtctt gaacacgctg aaaaacgtgg agctactatc ctggctgaag tggttggtta
     5401 cggaaatact tgtgatgcct accacatgac ttctccacat ccagaaggtc agggagctat
     5461 caaggccatc aaactagcct tggaagaagc tgagatttct ccagagcaag tagcctatgt
     5521 caatgctcac ggaacgtcaa ctcctgccaa tgaaaaagga gaaagtggtg ctatcgtagc
     5581 tgttcttggt aaggaagtac ctgtatcatc aaccaagtct tttacaggac atttgctggg
     5641 ggctgcgggt gcagtagaag ctatcgtcac catcgaagct atgcgtcata actttgtacc
     5701 aatgacagct gggacaagtg aagtatcaga ttatatcgaa gctaatgtcg tttatggaca
     5761 aggcttggag aaagaaattc catacgctat ttcaaatact tttggttttg gaggccacaa
     5821 tgcagttctt gctttcaaac gttgggagaa tagataagta tgaatttaaa cgatattaaa
     5881 gacttgatga ctcaatttga ccagtcaagt ttgagagaat tttcttataa aaatgggacg
     5941 gatgagttgc agtttagcaa gaatgaagcg agacctgtgc ctgaagttgc aactcaagtc
     6001 gctccagcac ccgttctagc aacaccgagt ccagtagctc ctacatctgc tccagcagag
     6061 actgtagcag aagaagttcc agctccagct gaagcaagtg tggctactga gggaaatctt
     6121 gtagagagtc cacttgttgg agtggtttac ttggctgctg gaccagataa acctgccttc
     6181 gttacagttg gtgatagtgt caaaaaaggt caaacattgg taattatcga agccatgaaa
     6241 gtcatgaatg aaatcccagc tcctaaggat ggtgtggtaa cggaaattct cgtctctaac
     6301 gaagaaatgg ttgagtttgg taaaggattg gtacgtatca aatgatcgat attcaaggaa
     6361 tcaaagaagc ccttccccac cgttatccta tgcttctagt ggaccgtgtc ttggaggtga
     6421 gcgaggatac cattgttgct atcaaaaatg tgaccatcaa cgagcctttc tttaacggcc
     6481 actttcctca atacccagtt atgccaggtg ttctgattat ggaagccttg gcgcaaactg
     6541 ctggtgtgtt ggagttatca aaacctgaaa ataaaggaaa actggtcttt tacgctggta
     6601 tggataaggt taagttcaag aagcaagttg taccaggcga ccaattggtt atgacagcga
     6661 cttttgtaaa acgtcgtggc accatagctg tggttgaagc aaaggctgaa gtggatggca
     6721 agcttgcagc cagtggtacc cttacttttg caattgggaa ctaaggaggt tctccatgtt
     6781 tcgaaaaatt ttaattgcca atcgtggtga aattgcggtt cgtattatcc gtgcggcacg
     6841 tgaattgggg atcgcaacgg tggcggttta ttcaactgct gataaggaag cccttcatac
     6901 gcttttggca gatgaagcag tttgtatcgg tcctggcaag gcaacagagt cttatctcaa
     6961 tattaatgcg gttctatcag ctgcagtctt gactgaggca gaagccattc acccaggttt
     7021 tggatttctc agcgaaaatt ccaaatttgc gaccatgtgt gaagaggtgg gaatcaagtt
     7081 tatcggtcca tctggtcatg taatggatat gatgggagac aagatcaatg cgcgtgctca
     7141 gatgatcaaa gcaggtgtgc ctgtcattcc aggttcagat ggagaagtgc ataactctga
     7201 ggaagctttg attgttgcag aaaaaattgg ctatcctgtt atgctcaagg cttcagcagg
     7261 tggaggtggt aaaggaattc gtaaggttga aaaaacagaa gacctcgttt tcgcctttga
     7321 aactgcctct agtgaagcca aggccaatta tggcaatggt gccatgtaca ttgaacgggt
     7381 tatctatcca gctcgtcaca tcgaggttca aatcctagga gatgaacatg gacatgtgat
     7441 tcacttgggt gaacgggatt gttctcttca acggaataac caaaaggttt tggaagaaag
     7501 tccttcgatt gcaatcggaa aaacgttgcg ccatgaaatc ggtgctgcgg ctgttcgagc
     7561 tgcagagtct gttggctatg agaatgcagg gaccattgag tttcttcttg atgaagcaag
     7621 tggcaatttc tatttcatgg agatgaatac tcgtgtacaa gtagaacatc cagtaacaga
     7681 gtttgtttca ggtgtggata tcgttaagga acaaattcgc attgcagcag gtcagccttt
     7741 gtctgttaag caagaagata ttgtcctacg cggtcatgcc atcgagtgtc gtatcaatgc
     7801 agaaaaccca gcctttaact ttgctccaag tccaggtaag attactaatc tctatctgcc
     7861 aagtggtgga gttggcttgc gcgtggattc agcagtttat ccaggctata ccattccgcc
     7921 ttattatgat agtatgattg ctaaaatcat cgttcacggc gaaaatcgtt ttgatgcttt
     7981 gatgaaaatg caacgtgccc tttatgaatt agagattgaa ggagtgcaga caaatgcaga
     8041 tttccagctt gacctcattt cagatcgcaa tgtcattgct ggggattatg atacttcctt
     8101 cttgatggaa acctttttac ccaagtatca agaaaaagaa taaaatgact tcaagagttt
     8161 aaaccgaaaa ggggaatcaa tggctctatt tagtaaaaaa gataagtata ttcgaatcaa
     8221 tcccaatcgt tcgattaggg aaaaacctca agccaagcca gaagttccag atgaattatt
     8281 ttctcagtgt ccgggttgta agcataccat ctatcagaag gatctgggaa gtgagcgtat
     8341 ctgtccacac tgtagctata cctttcgtat ttctgcccaa gaacgcttgg ttttgacgat
     8401 tgatatggga accttcaagg aattgtttac agggattgaa agcaaggatc ccttgcattt
     8461 ccctggttat caaaagaaac tagcaactat gcgtgaaaaa actggtctgg atgaagccgt
     8521 tgtgacagga actgctctta ttaaaggtca gactgtggct cttgggatta tggattccaa
     8581 ctttatcatg gcttctatgg gtacggttgt aggtgaaaaa atcactcgct tatttgagta
     8641 tgcgacggtt gaacagttgc cagttgttct cttcacagcc tctggtggag cccgtatgca
     8701 ggaaggaatc atgagtctca tgcagatggc caagatttct gcagcagtta aacgccattc
     8761 aaatgctggt ctcttttacc tgaccatttt gacagatcca acgactggtg gtgtgacagc
     8821 ttctttcgct atggaaggcg atattattct ggctgaacca cagagcttgg tcggttttgc
     8881 tgggcgtcgt gtcattgaaa atacggttcg tgaaagcttg cctgaggatt tccaaaaggc
     8941 agaattccta ttggaacatg gctttgtgga tgctatcgtt aaaagaagag atttgccaga
     9001 tacgattgct agcctagtca gattgcatgg agggagtcct agatgaatat tgcaaaaata
     9061 gtcagagaag cgcgtgagca gagtcacttg acaactttgg actttgcgac aggcattttt
     9121 gatgacttta tccaattaca cggtgaccgt tcttttcgtg atgatggtgc agttgttggt
     9181 ggtattggct ggcttggtga tcaagctgta acagtggttg gtatccaaaa aggcaagagt
     9241 ttacaagata acctcaagcg gaattttgga caaccgcatc cagaaggcta tcgcaaggcc
     9301 ttgcgtttga tgaaacaggc tgaaaagttt ggccgtccag ttgtgacctt tatcaataca
     9361 gcaggtgcct atcctggtgt gggagcggaa gaacgtggac agggagaagc cattgctcgc
     9421 aatctcatgg aaatgagtga tctgagagtt cctattatcg ctatcattat cggtgaaggt
     9481 ggttcaggtg gggctctggc tctagcagtc gcagaccgtg tctggatgct ggaaaattct
     9541 atctatgcta ttctcagtcc agaaggcttt gcttccattc tatggaagga cggcagtcgt
     9601 gccatggaag cggcagaact gatgaaaatc acttcacacg agttgttaga aatggacgtg
     9661 gtggataagg tgatctctga aacgggactt tctagtaaag aattgattaa gaatgttaaa
     9721 aaagaactcc aaacggagct agctagactt tcacaaaaat cgctagaaga gttgctggaa
     9781 gaacgctatc aaagatttag aaaatactaa gaatgactaa atgagactag aaaggtctca
     9841 ttttttatgg aaaaatgcaa ttcaggttga aaaattgaca gttgaggaga tagactataa
     9901 aatagacaaa aaaagaaata tactataaat gtgagcctac aacaatctat tttaagaagg
     9961 tacttgcaat gacaggtaca gaaacattta cagttatttc aactgaggac ttggagcaaa
    10021 cttcaggtgg tcttgctgtt tgggaagatg gatatagtag atggttatat tatagagaat
    10081 ttgctcctta tatgaggcaa ggggcactta attcttatat agatgcttgg aagtacggct
    10141 tccgaacagg gtaatctttc aaaaaagtac gatgagaaac acaaagaaac taagacaatt
    10201 tggaatattt ttgcttatta ttttactatc tacctattta cttaccacaa acaattggat
    10261 tgtatgtgac gatcatttta gggttaggag ctgatgtcta ttctcttatt ttaacagtgg
    10321 gattagtggg aagtttcctt ttctattaat ttggaggtta aaaaagaaaa agatgctctt
    10381 tatctttgag aaaaagagct ggaactggtc atttgtcttc tccttatttg caacttatgt
    10441 ggtttatcag attctcggta atttttgggc acgctatgct catttgatta atcataggaa
    10501 tattcatgat gagtatttta ccgtggttct ttcaaatgga caaccaacct ttttatcgac
    10561 tatcttatct tttgtcctgc ctgtaatcat cggtcctgtt tttgaggaga ctcttgatag
    10621 agggtatttt atgaatacct tctttcccta gtccaagtat tatttagatg tcatcttatc
    10681 aggccttatc tttgggctta gtcatttgat actatctcac agagatccaa ttagtttatt
    10741 atattatagt ctgattggtt tcttttttgc ctttgtttat cgttctaccg acaatctgag
    10801 attaacgatt ctctgccata gtttttttaa ctttctcaat catgcaaaac ctatctggat
    10861 ttttgtttac aattatatct attatcattt ttttagatag tgggaggcaa agaaaaagtg
    10921 tttgatatct atcaaacact ttttcttttt attgttcttc tgctacaaac tggctgagca
    10981 gtccattgat aaaacgggca gatttttgat cggagaagtc ctttgcaagc tcgatagctt
    11041 cattaacagc aaccaactga ggagtgtcaa atgaagtgat ttcaaagact cccaagcgaa
    11101 ggaggtttct ctccacgagc gttaagcgtt caatggtcca acctgctttt aaatgctgag
    11161 tgatttgctt atctagttct tcctttttag cttgaacacc agaaacgagg tctatcaaaa
    11221 aggctggaag ttgtacatcc gtatcttcac gatcatgagt ataggcgaaa cgacaagcag
    11281 tttcgacatc cgtaccgaac tcaaggctca tgagagcttg aaaagcgcat ttacggagtt
    11341 ggcgtctaga ttctaatagt ggactagtca ttgaggaagt cctcgtcaaa tagatctttc
    11401 aattctggtt ttggtgtttt atctgggacg atacctgcaa cgtgaatatt gatagcagcg
    11461 agttctacat cagccatatt acggacggca tctttgacag ctttctggat agcaaccgct
    11521 accttaggaa cttttactcc gtactcaagg tagagataga tatctgctgt gagttcttcg
    11581 tccacgtttt taagataaat gccacggccg agtgaaagtt ttgaaagggt atcagacact
    11641 gatctgtttg aaaaagagtg aacaccctct acctttgcag tagcgatagc aatgattttt
    11701 tcaagtacac gtggggcgat aacgatttcg ccaagttgtt cttcaattcc catagaatga
    11761 cctctttcta gagattaggc acgagaaacg taagttcctt ctgcagtgtt gataacgagt
    11821 ttttgtcctg cttcgatgaa gtctggaacg tttacgacaa gtccagtttc catcgttgct
    11881 ggtttaccag aacctgtaac agtagcacct ttgatagatg gttgagtttc agcaactgtc
    11941 aactcaacag tagtaggaac ggtgacaccg atcacttcag ttccgtagaa ttggattttc
    12001 acatcagagt tttcaaggat gtaaagcaat tcgttttcaa cattgactac agggatttcg
    12061 tattggtcgt aagtttctgt attcatgaag tatgctgtgt catccatttt gtacaagtat
    12121 tgagctggga cagtctcgat aatagcttgt tcaaattttt cctctggacg gtagcttgtg
    12181 tcaaatgtag aaccagtacg gacatcacgt aatttcatac gcatgatcgt gtttccttta
    12241 cctggtttgt ggtgactagc ttccaaaacg cgaatcaatt tgccgtcagc tgtttcaaag
    12301 gtcataccag cttttaattt acttgcttca atcatgtttt tacctcttta ataaatatta
    12361 ttactcttca ttttaccata aaatactctg gaaataaagc caaaatagtt attgggagtt
    12421 ggtaggagcg aaaaagaata ttggctagtc aggtggagtg gttaatgtta aagagtatcc
    12481 actatatttc ttctcatact caatggaaat caaagagcaa actaggaagc tagccgcaag
    12541 ctgtatttga gtacggtaat gtgacgctga cgtggtctga agagattttc gaagagtatt
    12601 atatttcaaa aggccgaagt aagtttactc cgacctgtta gtattgtctt aaaaagattg
    12661 attttttatt ctggttctac caaaatttta atttgtgact tatcttgagt taattcgata
    12721 aagccttctt cgacgatatt ttccaattta attttcttag taactaattt ttcagcggag
    12781 aagtagcctt gttccatcaa ttctaatact ttagggaaga tatgacgata agcaatgatt
    12841 ccttttagtg tcttttcttg gattgcaaat tcattcggat taatatttgc ttctcgttcc
    12901 cagatagaga ccaccatgca ctcacctgct ttatgtacgg cagctaaggc ttgtcctaaa
    12961 actactggca cacccgttac ttcataagaa acatctacac caccgtttgt taaacgatga
    13021 atagcttcaa cagctgtttc accttcttcc ggacggacaa cgatagctcc taactcttca
    13081 gcttttgctt gacgttcagg tgatagttca acagcataaa tcttagaagc accagctgca
    13141 cgaagagctt ctacaattaa tagaccaatc gggcctaaac caaagacaac agctgtatcg
    13201 ccagccttca aagaagattg acgaacagca tagactgcaa cagcagcggg ttcagtaaga
    13261 gcagcttgct catagctcaa gctatctgga atgacatgta ctaagtcacc gtctaaaaca
    13321 caatatttgg caaatccacc gtctgcagcc aaaccgacaa aattaaggtt tggatccaaa
    13381 ttataatcac caactaagtt atttttagct agaattggtt ccacagcaac acgatcacca
    13441 actttaacac aggtaacatc gcttccgact tctatgattt caccagaaaa ttcatgtccc
    13501 agtgttaccg gtgctttttg accagaatag acgtgctcat ctgttgggat aaagataggt
    13561 ccatctaaaa attcatggag gtcagtacca caaattcctg tgaacttaac tgcaactttt
    13621 acttggtgcg gaagtacttc aggaacttct atttcttgaa tacgaacatc tttcgctgca
    13681 tgccagcgag ctgccttcat tgtagccata taaataactc cttattgttg cgatttttag
    13741 ttttcttgtt tggaaacttt acacgcaata ttgtaaacgt tttctttcta tttgtcaaga
    13801 aaaaaccaac cttagggctg gttttgttct gtctagtttt ctttcaactt cgccaattcc
    13861 tgtgcaagta gtttaagggc aacttgtggg ttggcttggc ctttggttgc cttcataagg
    13921 aatcctgtaa aggccttgtc ggcgttacgt ttgcctgact tgaagtcggc aacagcagct
    13981 tcgttatcgg caaagacttg gtggatgatt gggatcaaga tagctggatc tgaaatttga
    14041 accatacctg ctttttccac gtattcacgc gcgccaccgc catttttagc tagatggaca
    14101 aagactttct tggcaatctt agatgaaata gtaccgtctt cgatgatggt aatcatttca
    14161 accaagtttt ctggtgtcaa ttcgatttgt tccagtgttt taccttcagc attcaagaac
    14221 tgagcgactt ccccttggag ccagttagag acttgtttgg catcaccacc tagggcaaca
    14281 gctttttcaa agaagtcaga agtgacttta ttagcagtca actgactagc atcgtagtct
    14341 gataaaccaa ggtcagatac ataacgcgca cgacgttctt ttggaaactc tggcaactca
    14401 gtctgcattt cctcaatcca ctcgtcagaa atttcaaaga ggggtaggtc tggttctggg
    14461 aagtagcggt agtcagcagc cccttccttg acacgcatga ggatggttgt tttgttagct
    14521 tcatcgtaac ggcgtgtttc ttggcggatt tgaccacctg agcgaagaat ttcagcctgg
    14581 cgttggactt cgtattcaag acctttacga acgtttgaga aggagttgag gttcttcaat
    14641 tcagtcttgg taccgaattt ttcttgacca taagggcgaa gggagatgtt ggcatccaca
    14701 cgcatagaac cttcttccat cttaacgtca gaaatgccag cgtactggat aacttccttg
    14761 agggctgtca gataagcata ggcctcctct ggcgaacgca tatcggcttc agatacaatc
    14821 tcaatcaaag gtaccccttg gcggttaagg tcaacgtaag agtagccgtc tgtaccgtgg
    14881 gtgtttttac cagcgtcttc ctctaagtgg gcgcgttcga taccaatttt cttggtcgta
    14941 ccgtcttcta gctcgacttc aatccagccg ttataaccga ttggctcatc aaactgagaa
    15001 atttggtagg ctttgggatt atcagggtag aagtagttct tgcggtcaaa gtgcattttt
    15061 ttgtggatgt ccatgttgag ggcaagagca gccttgattc cggcatcaac aaccccttta
    15121 ttgagaactg gtagaactcc tgggaaagac cagtcaatca cgttagtgtt ggcattttgg
    15181 tcatttccaa agtgggcaga agtaggtgag aagatttttg aattggtgtt gagctctacg
    15241 tggacttcaa gtccgatgac tgtttcaaag ttcattagtt gtcacctcca aaaatcacgg
    15301 gttgttgttt gtggtagtct gttgttgctt caaaagcagc agcagcttgg taaatggttt
    15361 cctcagagta cttgggacca atcaattgga gtccgacagg tagaccttga gagaatccag
    15421 caggaatcga aattccaggg aaacctgcta agtttacagg tatggtcaag aggtcagcca
    15481 agtacatggc aactgggtca tggttgagtg agtccaagtc ataggcaaca cttggagcag
    15541 ttggacccaa aatcaaatcg taatccgcga agactttttc gaaatcttga atgatgaggg
    15601 tacggacttg accagccttt ttgtagtagg catcatagta acctgatgaa agactgaaag
    15661 tacccagcat gatacgacgt tttacctctt caccaaaacc ttggcttcgg ctgtttacat
    15721 agatttcatc aaggttggtt gcatcttctg cgcgatagcc gtaacggata ccgtcaaagc
    15781 gttgcaagtt tgatgaagct tctgatgaag cgatgatgta gtatacggca actccgtatt
    15841 tagagtgagg aaggctgact tcttcgacaa tagcaccaag tttttcaaag tgtttagcgg
    15901 catttagaat ggtttcctta acctctgggt taattccttc accaaggtat tccttaggca
    15961 aagcgatttt catacccttg atgtcttggc cgatttttga agtaaagtcg gcgatgcgga
    16021 caggagcaga agtagagtct ttagcatctt cgctggcaat agcgttgagc aagagggcat
    16081 tttccttaac agtgggagca aaaggtccaa tctggtctaa tgagctacca aaggcaatga
    16141 gaccgaaacg tgaaactgtt ccgtaggttg gtttgagacc aacgattccg ttgaaggcag
    16201 caggttggcg gatggaacca ccagtatcag aaccaagtga caagcgaact tgtcctgagg
    16261 ctacagctgc ggcagaacca cttgatgacc caccaggaac cttgctgtgg tcccaagcgt
    16321 ttttagttgc tccgtagtgt gaagtttcac ctgaaccacc catagcaaat tcgtccatgt
    16381 tggtctttcc aacgacaatc atgcccttgg tttttgcatt ggcaacagct gtcgcatcaa
    16441 agattggctc atagttgtag agcatttttg aggcagcagt tgtgagaata ccgtctgtag
    16501 agatgttatc cttaacagca agtggaattc ctgaaaggac attgtcagca tcaattccag
    16561 cttcatcaat ggctttagct tgaacaagag cttgctcctc agcgatggtg acaaatgaat
    16621 tgagggcttc ctcacgagac ttgatatttt caagtgttgc ttgggtcaat tctgttgcag
    16681 aaatttcctt agagacaagg agattgtgca actcttcaat agttttatcg ttaaaagtca
    16741 ttaggcatct cctccatcgt ctaggatagc tggcaccttg atatagtagt tgtctttttc
    16801 aggtacgttt ttaaacaagc gatcacggtc tgttccttct tcggccacat cagggcggag
    16861 tacagtcttg cggtcagcca tagtcgtagt aggtgcgaca ccagttgtgt caacttcgcc
    16921 cagcaattca accatgtcaa caatcttaga caaggtggtc gcaaaggcag cagtttcttc
    16981 ttcagagaat cttaattttg aaagattggc aacgtgtgtt acctcttctt gcgtaatttt
    17041 catcttgcat cctttcgtga aatgatgatt tttagtctgt tctattttac catattttcc
    17101 tataaataag ggagggggaa gtgaaaagaa atagaaattg aaaaaaatgc taaaatccga
    17161 tataatggag tgttgaaagg aatggtaaaa tccaatgtaa aaatcattct cagctattga
    17221 aacaagaaaa atagagaatc aaagaaagag aacttatgaa tattcaagaa gaaattaaga
    17281 aacgtcgtac ctttgccatt atttcccacc cggacgcggg gaaaacaacc atcactgagc
    17341 agttactcta ctttgggggt gagattcgtg aggctggtac ggtaaaaggg aagaaaacag
    17401 ggacttttgc taaatctgac tggatggata tcgagaagca acgtgggatt tctgttactt
    17461 catctgttat gcaatttgac tacgacggca agcgcgtgaa tatcttagac acgccagggc
    17521 acgaggactt ctcagaagat acctatcgta ccttgatggc ggtggatgct gcggtcatgg
    17581 tcgtggactc tgccaagggg atcgaggctc aaacaaagaa actgtttgag gttgtgaaac
    17641 atcgtggcat tccagtcttt acctttatga acaagttgga tcgtgacggt cgtgagcctt
    17701 tggatctctt gcaagaattg gaagaaatct tgggcattgc tagctaccct atgaactggc
    17761 ctatcgggat ggggaaagcc tttgagggct tgtatgacct ctataaccaa cgtttagagc
    17821 tttacaaagg ggatgagcgt tttgccagtc tagaagacgg ggacaaactc tttggtagca
    17881 atcctttcta cgatcaagtc aaggatgaca ttgagctttt aaatgaagct gggaatgagt
    17941 tttcagagga agctattctg gctggagaat tgacgcctgt ctttttcggt tcagccctga
    18001 caaactttgg tgtgcagacc ttccttgaaa ccttcctcaa gtttgctcca gaaccacatg
    18061 gtcacaagaa aacagatggt gaaattgtgg atccttatga caaggatttc tcaggctttg
    18121 tctttaaaat ccaagccaac atggaccctc gtcaccgtga ccgtattgcc tttgtccgta
    18181 tcgtatctgg cgaatttgag cgcggcatga gtgttaatct ccctcgtact ggtaaggggg
    18241 ctaaactgtc taatgttact cagtttatgg cggaaagtcg tgagaatgtg accaatgccg
    18301 tggcaggtga tattatcggg gtttacgata caggtactta tcaagttggg gataccttga
    18361 cagttggtaa aaacaagttt gaatttgaac cactgccaac ctttactcct gaaattttca
    18421 tgaaagtttc tgctaagaat gttatgaagc aaaaatcctt ccacaagggg attgagcaat
    18481 tggtgcaaga aggagccgtt cagctttata agaattacca aacaggtgag tacatgctag
    18541 gcgctgtagg tcaactccag tttgaagtct ttaaacaccg catggaaggt gagtacaatg
    18601 cggaagtagt tatgaaccca atgggtaaaa agaccgttcg ttggatcaag cctgaggact
    18661 tggatgaacg gatgtcgtca agtcgcaata tcttagccaa agaccgtttt gaccaaccag
    18721 tctttctctt tgaaaatgac tttgccctcc gctggtttgc ggacaagtat ccagacgtag
    18781 agttagagga gaagatgtga ctcagtacca acaatttgga actaaagttc caaattgttg
    18841 gtactgagtc actaactacg tttggcaaat agaatcgatt tgccaaactc cgtgtcgtaa
    18901 tctaataatc ggtaaccgct atggcggctt acctaaacgc ttcactagga aaaatccacg
    18961 aatggtattg atttgtggat ttttccgtcg tagcagaaag taggtagcct agctaactgc
    19021 cttactaact acgtttggca aatgaaatcg atttgtaaaa ctccgtgtcg taatgtaaaa
    19081 attgtaaacc gtaatgggac ttcatctaaa atctccactg gtatagtttt acgaacgaat
    19141 aggcgaaaat aatggttacg tagaaacata tgatgggaat aatatgatgg gaataaaaag
    19201 aaatgagata aaaagtgaaa gaagagaaaa aagcgattgt cttaggtgca gataatgctt
    19261 atatggataa agttgaaaca acaataaaat ctctttgtgt tcatcattat aatcttaagt
    19321 tttatgtttt taatgatgac cttccgcgag aatggttcca attgatggaa aaaagactag
    19381 agactttgaa tagtgagatt gtgaatgttt agattgacag taatattctg aaaggttatc
    19441 gtctcccctt tgagggactt tcatatgcgg cttttttagg tattttattc caaagtatgt
    19501 aagcgagtct cgtgtactgt atttggattc agatattgtt gtaagaaaat cgatagatga
    19561 gctgtgggat ttggacttga cggctatacc cttagctgca gttagagatg atttttatac
    19621 acataatttt aattctggtg ttctgttaat caacgatggc atgtggagag cagaaaatgt
    19681 cacgcaagac ctgatttaag acacaaataa aaaatcttcc aattcccttg caaaaaacaa
    19741 gaaagtgtga taacatagta cggtatgtgg tgctagcaca tccgctatat tagatctaat
    19801 aggaggaaaa cacaatggct aaagtatgtt actttacagg tcgtaagact gtatcaggaa
    19861 acaaccgttc acacgcgatg aaccaaacaa aacgtgccgt aaaaccaaac cttcaaaaag
    19921 ttactgttct tatcgatggt aaacctaaaa aagtttgggc ttcagctcgt gctttgaaat
    19981 caggtaaagt tgaacgcgtt taataataaa agcaaaggag accttagggt cttttttctt
    20041 ttattgtggg tataacatca tttgaaaaat agagtaaata tccgctgata catcattctg
    20101 cttttacact tgggctgaaa tatg
//
LOCUS       DAVFJR010000038        19579 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVFJR010000038 DAVFJR010000000
VERSION     DAVFJR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.039"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            66..299
                     /gene="secG"
                     /locus_tag="VU722_001698"
     CDS             66..299
                     /gene="secG"
                     /locus_tag="VU722_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU1772630.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            401..2755
                     /gene="rnr"
                     /locus_tag="VU722_001699"
     CDS             401..2755
                     /gene="rnr"
                     /locus_tag="VU722_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU1772631.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMCAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDEKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            2718..3185
                     /gene="smpB"
                     /locus_tag="VU722_001700"
     CDS             2718..3185
                     /gene="smpB"
                     /locus_tag="VU722_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU1772632.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            3201..4061
                     /gene="tehB"
                     /locus_tag="VU722_001701"
     CDS             3201..4061
                     /gene="tehB"
                     /locus_tag="VU722_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU1772633.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            4134..5087
                     /gene="coiA"
                     /locus_tag="VU722_001702"
     CDS             4134..5087
                     /gene="coiA"
                     /locus_tag="VU722_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU1772634.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            5106..6908
                     /gene="pepF"
                     /locus_tag="VU722_001703"
     CDS             5106..6908
                     /gene="pepF"
                     /locus_tag="VU722_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU1772635.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     GRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            6910..7623
                     /locus_tag="VU722_001704"
     CDS             6910..7623
                     /locus_tag="VU722_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU1772636.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            7690..8631
                     /gene="prsA"
                     /locus_tag="VU722_001705"
     CDS             7690..8631
                     /gene="prsA"
                     /locus_tag="VU722_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU1772637.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGSGDSSSSSSTSNE"
     gene            complement(8748..9089)
                     /locus_tag="VU722_001706"
                     /pseudo
     CDS             complement(8748..9089)
                     /locus_tag="VU722_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            9502..9597
                     /locus_tag="VU722_001707"
                     /pseudo
     CDS             9502..9597
                     /locus_tag="VU722_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9850..10470)
                     /locus_tag="VU722_001708"
     CDS             complement(9850..10470)
                     /locus_tag="VU722_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1772638.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(10470..10952)
                     /locus_tag="VU722_001709"
     CDS             complement(10470..10952)
                     /locus_tag="VU722_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU1772639.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGNKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(10952..11794)
                     /locus_tag="VU722_001710"
     CDS             complement(10952..11794)
                     /locus_tag="VU722_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU1772640.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(11889..12689)
                     /locus_tag="VU722_001711"
     CDS             complement(11889..12689)
                     /locus_tag="VU722_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU1772641.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFFES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            12833..14212
                     /gene="glmU"
                     /locus_tag="VU722_001712"
     CDS             12833..14212
                     /gene="glmU"
                     /locus_tag="VU722_001712"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU1772642.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVASISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            14222..14767
                     /locus_tag="VU722_001713"
     CDS             14222..14767
                     /locus_tag="VU722_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1772643.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            14779..15093
                     /locus_tag="VU722_001714"
     CDS             14779..15093
                     /locus_tag="VU722_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU1772644.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            15110..15802
                     /locus_tag="VU722_001715"
     CDS             15110..15802
                     /locus_tag="VU722_001715"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU1772645.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIVTGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKTLD"
     gene            15879..16370
                     /gene="rocS"
                     /locus_tag="VU722_001716"
     CDS             15879..16370
                     /gene="rocS"
                     /locus_tag="VU722_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU1772646.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            16468..17058
                     /locus_tag="VU722_001717"
     CDS             16468..17058
                     /locus_tag="VU722_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU1772647.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTNVPLKSFINGLTGITAETLKDAPPVEKVIKEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            17067..18830
                     /locus_tag="VU722_001718"
     CDS             17067..18830
                     /locus_tag="VU722_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU1772648.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDTYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     SQEDPEYTDLLLKKALEFFEF"
     gene            19192..19579
                     /locus_tag="VU722_001719"
                     /pseudo
     CDS             19192..19579
                     /locus_tag="VU722_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6183 a         3480 c         4197 g         5719 t
ORIGIN      
        1 taaccctaca tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt
       61 ttgatatgta taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg
      121 caattttcat gcaaccaacc aaaaaccaat ctagcaatgt atttgatgcc agttcaggtg
      181 atttgtttga acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga
      241 ttttagtctt tttctggcta gccattgcct tagcattgac ggtattatca agtagataag
      301 aaaataatgg gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg
      361 ttttacagta aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga
      421 atatttacaa gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga
      481 cagttccaag gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca
      541 gattcgcttt gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac
      601 cctcaagggg atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga
      661 ggaggacgac ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt
      721 cgaggtagtg attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat
      781 tattgatatc ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga
      841 aaagcctaag tatgctggct atattcgttc aaaaaatcag aaaatcagtc aaccgattta
      901 tgttaagaaa ccagccctaa aattagaagg aacagaagtt ctcaaagtct ttatcgataa
      961 atacccaagc aagaaacatg atttctttgt cgcgagtgtt ctcgatgtgg tgggacactc
     1021 aacggatgtc ggaattgatg ttcttgaggt cttggaatca atggacattg tatccgagtt
     1081 tccagaagct gttgttaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat
     1141 ggaaggtcgt ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa
     1201 ggacttggac gatgcagtgc atatcaaggc tctgaaaaat ggtaatctgg agcttggggt
     1261 tcacatcgca gatgtttcct attatgtgac cgagggttct gcccttgaca aggaagccct
     1321 taaccgtgcg acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact
     1381 atcaaatggc atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat
     1441 ggagattgat aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac
     1501 cagttttcgt atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag
     1561 aaaagaatat cataaaattg tatcaagtat cgaactcatg gccaagcttc atgaaacttt
     1621 agaaaacatg cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt
     1681 agtggataaa caaggtaagc ctgttgatat cgttcttcgg cagcgtggta ttgccgagcg
     1741 gatgattgag tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt
     1801 ggatttgcct tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt
     1861 tattgattat gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca
     1921 ggaggcactt caagacatca tgtgtgctgt tgagggagaa ccttatgcag atgtattgtc
     1981 catgatgctt cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta
     2041 tggactagct gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct
     2101 tcttgttcac cgtatgattc gggattacgg tcgttctaag gaaatagcag agcattttga
     2161 acaagtgatt ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc
     2221 tgagcgtgaa gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga
     2281 gtatgatgca gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac
     2341 agttgaaggc ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga
     2401 tttgactctt cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat
     2461 ccgtgttgaa agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga
     2521 gtttgatgtg attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc
     2581 aaatcgtcgt tcggataaga aggaagacaa gagaaaatta ggacgctcaa atgataagcg
     2641 taagcattca caaaaagacg agaagaaaaa aggaaagaaa cctttttaca aggaagtagc
     2701 taagaaagga gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg
     2761 cacgccacga ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg
     2821 aaatcaagag tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa
     2881 atggagaagt ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga
     2941 accaggaacc agaacgtcgt cgtaaactcc tgctccataa aaagcaaatt caaaaattgg
     3001 aacaagagac caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg
     3061 gctacgctaa gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt
     3121 ctatcaaacg tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc
     3181 gataaaaaga ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga
     3241 ataaacaaac aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg
     3301 ggaaaattac tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag
     3361 ttctagctga acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct
     3421 ggcaccgagt ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac
     3481 ctgaggatta ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg
     3541 ccatgcagac agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt
     3601 ctctttttct agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc
     3661 ttgaaatctt gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg
     3721 atatcaattc agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca
     3781 tgtttctaca agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg
     3841 ttggtggtta caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta
     3901 acttcccatt cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg
     3961 ttaagtacaa tgaaaatcca ggccatttgc accgtcgcga tgagaatggc aatcgtattc
     4021 aactacgctt tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga
     4081 attttcctga tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg
     4141 ttgcgagaga tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag
     4201 catacacctg cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga
     4261 cgcattttgc ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag
     4321 aacacctggc caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat
     4381 tagagtaccc gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag
     4441 ctctagaagt tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct
     4501 atcgtagtca gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc
     4561 gtttgactcg tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt
     4621 gggaattaga caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc
     4681 gcggtaaact ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa
     4741 tattgcgtct tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg
     4801 acatctgtcg ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac
     4861 aagcagaagc ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc
     4921 cacaaattcg accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt
     4981 atcagcactt ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc
     5041 caccagcctt ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga
     5101 atctaatggt attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga
     5161 tctacccaac tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga
     5221 cagtagccca gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg
     5281 aattttctct tgaaatggaa cgccagatgg agaagcttta cgtttatgct catatgaaga
     5341 atgaccagga tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct
     5401 acagccagtt agaccaagcc ttttcattct atgagcctga atttatggag attagcgaaa
     5461 agcagtatgc tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg
     5521 acaagctctt gcaaggcaag gatcacgttc tctcacaacg tgaagaagaa ttattggctg
     5581 gagctggaga aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata
     5641 ttgtgttccc ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggattt
     5701 acacacgttt gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt
     5761 atgcgactta cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg
     5821 tgcaaaatta ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gccctcgcag
     5881 cgaattttgt tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc
     5941 cactcttaca tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga
     6001 tgtacgatgt ctacacaccg ctttcatctg ttgaatacag ttttacctac caagaagcct
     6061 tgaaaaaagc agaagatgct ttggtagtct tgggtgagga ttacttgggc cgtgttaaac
     6121 gtgccttcag cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct
     6181 actctggtgg ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg
     6241 acaatctctt tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg
     6301 aaactcagcc ttatgtttac ggagattact ctatcttttt ggctgagatt gcctcaacta
     6361 ccaatgaaaa tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct
     6421 ttgctattct caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat
     6481 ttgctgagtt tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg
     6541 atttcctaaa taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag
     6601 acaatcctga aatccaatac gagtgggctc gcattccaca cttctactat aactactatg
     6661 tatatcaata ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg
     6721 gtagtcaaga agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc
     6781 cacttaatgt catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg
     6841 cctttgcagt ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat
     6901 tggcataaaa tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc
     6961 gtcaaagaag aaattgtaga cttgatgcgt cagcgtcaaa agcaagtcac aggtttcttg
     7021 aaagaattgg aagattttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt
     7081 gcttatttcc gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg
     7141 gctatcggtt tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact
     7201 attgatcgta atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt
     7261 cgcaagcaaa tcactctcct agagggagat gcggtggatg tcttatctac actgacagag
     7321 tcttatgatt tcgtctttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa
     7381 atcctcaaac atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt
     7441 gatgttgcca aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt
     7501 caaaaattat ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta
     7561 ggagatggta ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa
     7621 tgattttcag aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa
     7681 ggagtagaca tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact
     7741 ttagcagctt gttcgaaagg gtcagaaggg gcagacctta tcagcatgaa aggggatgtc
     7801 atcacagaac atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg
     7861 ttaaatatga ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa
     7921 gaggttgatg atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc
     7981 ttgtcacaag caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta
     8041 gttgagttgg cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa
     8101 gcctttgatg agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat
     8161 aaggccaaag aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc
     8221 aaagataatt caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct
     8281 gcttcaacag aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt
     8341 gtttctgatg tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta
     8401 aaactcacta agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa
     8461 actgttatct tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa
     8521 gaattgcaag cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa
     8581 tatatcggta gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca
     8641 atgagtcagg gaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa
     8701 cgcatagtac aaggtttgta ctgcccccca aaagttagac aattaattta tccgaaggac
     8761 ttagttctgt attgcacagg gctaagtcct tttagtttta ccttaattct cttattgttg
     8821 taataatcaa tatagtctat aatggcttgt tccaattgat taagtgattt aaatgttttc
     8881 tcatagccat aaaacatttc ggattttaaa atgccaaaga aagattccat cctaccgttg
     8941 tcttggctgt ttcctttgcg tgacatagat gcttgaattc ccttactctc taggaaccga
     9001 tgataagaat cgtgttggta ttgccagcct tggtcactat ggagaatcgt attctcgtag
     9061 tgcttctctt tgaatgcctg ttccaacatt aacgatcaat caatttaatc atgtacctaa
     9121 tattagaatt gtttatctca aatttatttg aaagcttctc taagctatat ccttgttttc
     9181 taagttcata gatctgaact ttatcatcat aagttaattt cataataaaa acactccaaa
     9241 agttagattt tttctgtcta acttttgggg tgcagttcat ttaacacctg ataatatgcg
     9301 ttttttattt taaagacttt ttgaccagcc tcattttttt aacttgatac tcagtgaaaa
     9361 gcaaagatta aactaggaag ctagctgtag gctgttcaaa gaacagcttt gaggttgcag
     9421 ataaaacttg tgaggtaacc aacatatata atgtgaagct gacgtggttt gaatagattt
     9481 tagaagagta tgagtttgga agttttaatg gataatgcaa gattccatag aatgggtaag
     9541 ctagagttct tatgtgaaga gtttgggcat aaacttttac cttttcctcc ctactcatct
     9601 tagtatagaa aagtgaatct gaaatagtac ataactgctt ctaaaacatt cttataaatt
     9661 gatttaaatt ctcaaatcat attattcagt tcttatttca ttttgctcta caatcctgtt
     9721 gagaagacac gtgttcatat caaaaaggta ttggcaagtt gcaatacctt tttacaaggt
     9781 tcttttgtct tatttttgtt tcaactgact atatctccta tggttctagt tcagaaggct
     9841 aggctataat tatgattgat aagaagtatc attccaagta ttgagagtga atgtttcaaa
     9901 atcatgggtt tctataatgg tcaggctggc atttgctaga ccgccatctt tacgaagaag
     9961 tggttcttta tagcctagga gagtacgaag actggcagta agattggcgc cgtgtccgac
    10021 aattagaata cgctcagctg gactatcttt taatgatttg ataaattgga tggtccgctg
    10081 agttgtacta tagagggatt cggctccgaa cattcgagtg tcaaattgag caagatttga
    10141 acgaaaagcc tggatttgtt gcgggtaaat agcttccagg gttgcaattt tcaaaccttc
    10201 taacttccca agttgccatt cacggagatt aggaacgatt tctaaagaac agggggtatg
    10261 gagttgactt tggataatct cagcagattt gaccgctcga ggtaaatcac ttgaataaat
    10321 ctgatcaaaa ggaatttcct tgagatactg gccaagtcgt tttagggttt caatggattc
    10381 aggaagaaga ggagaatcac cgctagcacc ttgaaaacga ccttcttggt tccagagggt
    10441 acgaccgtgg cggacaaagt agagtttcat tacttgatgt cctccaaaat atctacaaag
    10501 tctgccttta caaagctagc caagtcttgt ggcgcgacga taatgctgtg tccgacttcg
    10561 cctgcagaga caatcattcg atccaaatct agagcaattt tatcgataaa aatgtgataa
    10621 ttgtgtttct gacgaattcc gacaggatta ttggctccat gaatgtaacc agttgttttt
    10681 tctaagtcct tttgtggaat catgctcact tttttattgc cagaaatttt agctagtttc
    10741 ttttcagaca agtgctgagt gatagggaca attccgataa tcggtccggt cttgtttccc
    10801 aaaagcgcca aggttttgaa aatctgatct cgttcataac cttgaggaag ctctccttct
    10861 agggcattga tttgaatccc ctgatgaggg atagctgctt tagataggat ttgttccacc
    10921 aatgtttttt tgattttaac tttttttgcc attatttata tttatcctcc aattgactca
    10981 tccaaatacc aagccagatt cccagcgcaa agaagaaggc gatgatgaca taaccgacaa
    11041 gtgaaagtcc tgtgtattgg atactttcag cgtttcctgc atttggaatt aagatcaaaa
    11101 gggtacttga taggacgata ccgatgatga aatgatagac gcgtgagtgg tagttgttta
    11161 aggcataatc catcaatttt gaaaaaacga tgagagttgc acctgcacca attccaatcg
    11221 gaaagaaggt tcccaagaga tcaaaagttt taaaaccagt caacatagga gcatagagtc
    11281 ccaaaatcaa aagtaaattc gatgggctga ggccaggaac caagacgcca agggccaata
    11341 gtgcacctgc taggacgaag ttaagaaagc tggcgcttaa ggttccaacg acaaaattta
    11401 aggcatagag tcctaatcca gaaatgataa aggttgtcca taaccaagct aaatcaatct
    11461 tgtctcggtc agattctcga gttgattctt tgaggaggct aggaactgta ccgataatag
    11521 ctcccgcaaa gctccataat acaaagacct gataattttc aagcaggtat tcaatcgggt
    11581 aggaaaataa gccgattccc agaagcatac cgatggcaac tggaataaag tacaaaacat
    11641 tttctttaag gtctttaaag ggatgggcca gaaagccaat cattcgttca tagattccta
    11701 agattgctgc tagaactcct ccggaaattc ccggtaggat aaatccaaga gcaattacaa
    11761 tccctttaat aacgcgtgct aaccatgaga gcatatattt cctccaacta tttctatttc
    11821 aaaaaatcct tactatattg tatcacaatc agacacaaaa agaaaaagca aatgataaac
    11881 aaatgctttt aaggttttaa aaagagtttt cgaaaggttt cttctttatt ttttaaggga
    11941 gagataacgt tgatatctaa atcgtggtca aagccggcaa tttttccttt agatgtgtat
    12001 tggtgaatat cataatctaa atcagtttta ggactgctct caaaaaatcc tgagtctgag
    12061 ccgtaggacg gaatccaaac agaggtaaac ttgcctgtat caatactgtg ttcttccatg
    12121 aagtagacac caacgtagat gccgatgttt ttagcaccta gtgatgctag ttttgctcga
    12181 aaattttcga caccttcgtt catattagac atggttttgt cttccacgtc aagccaatag
    12241 taactagggc tgtaaggaga ggcagcattg tagaaaactt cggcagcctt ttccatttct
    12301 tggacacttt ttccagctac ataagcgtag acagcaactg ggacattccg cttttgaagt
    12361 tcagtgatat gactcttata ggccttgtct attccattga taaatgaagc atcattttct
    12421 tttgtcgttt gagcaccact gtgaacacga acaatagcac ctgaaatatt ttgtgagagg
    12481 gcatcgtagt tgatttcctc aggacgctgc cagccagaga ggtcaataat cggtttgtct
    12541 aagtgtttca aagcctgtgc ttcaatctgt gctatattgg attttgtttt aaacgattgg
    12601 ttgtcattaa gtgggcgatt gatgattaaa atgaacatca taatccccaa aaaactaaat
    12661 aaaataagtg gatgaatttg ttttctcata tcttataatt ctaccctaaa aatcaaaaaa
    12721 aatcaaaaaa atgggttaag gaagagactt tagagcattt tttcattcaa gagtgcggaa
    12781 tgatttgaaa tatggtataa taaaagggaa tttctacaga aaagagaaaa ttatgtcaaa
    12841 ttttgccatt attttagcag cgggtaaagg gactcgcatg aaatctgatt tgccaaaagt
    12901 tttgcacaag gttgcgagta tttctatgtt ggaacatgtt ttccgtagtg tgggagctat
    12961 ccaacctgaa aagacagtaa cagttgtagg acacaaggca gaattggttg aggaggtctt
    13021 ggctggacag acagaatttg tgactcaatc tgaacagctg ggaactggtc atgcagttat
    13081 gatgacagaa cctatcttag aaggtttgtc aggacacacc ttggtcattg caggagatac
    13141 tcctttaatc actggtgaaa gcttgaaaaa cttgattgat ttccatatca atcataaaaa
    13201 tgtggccact atcttgactg ctgaaacgga taatcctttt ggctatggac gaattgttcg
    13261 taatgacaat gctgaggttc ttcgtattgt tgagcagaag gatgctacag attttgaaaa
    13321 gcaaatcaag gaaatcaaca ctggaacata cgtctttgac aacgagcgtt tgtttgaggc
    13381 tttgaaaaat atcaatacca ataacgctca aggcgaatac tatattacag acgtcattgg
    13441 tattttccgt gaaactggtg aaaaagttgg cgcttatact ttgaaagatt ttgatgaaag
    13501 tcttggggta aatgaccgtg tggcgcttgc gacagctgag tcagttatgc gtcgtcgcat
    13561 caatcataaa cacatggtca acggtgttag ctttgtcaat ccagaagcaa cttatatcga
    13621 tattgatgtt gagattgctc cggaagttca aatcgaagcc aatgttacct tgaaagggca
    13681 aacgaaaatt ggtgctgaga ctgttttgac aaacggtact tatgtagtgg acagcactat
    13741 cggagcagga gcggtcatta ccaattctat gattgaggaa agtagtgttg cagacggtgt
    13801 gacagtcggt ccttatgctc acattcgtcc aaattcaagt ctgggtgccc aagttcatat
    13861 tggtaacttt gttgaggtga aaggatcttc aatcggtgag aataccaagg ctggtcattt
    13921 gacttatatc ggaaactgtg aagtgggaag caacgttaat ttcggtgctg gaactattac
    13981 agtcaactat gatggcaaaa acaaatacaa gacagtcatt ggagacaatg tctttgttgg
    14041 ttcaaattca accattattg caccagtaga acttggtgac aattccctcg ttggtgctgg
    14101 ttcaactatt actaaagacg tgccagcaga tgctattgct attggtcgcg gtcgtcagat
    14161 caataaagac gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt aggaacctat
    14221 catggagttt gaagaaaaaa cgcttagccg aaaagaaatc tatcaaggac caatatttaa
    14281 actggtccaa gatcaggttg aattaccaga aggcaaggga actgcccaac gggatttgat
    14341 tttccacaat ggggctgtct gtgttttagc agtaacggat gaacaaaaac ttatcttggt
    14401 caagcagtac cgcaaagcta tcgaggctgt ctcttacgaa attccagccg gaaaattgga
    14461 ggtaggagaa aacacagccc ctgtggcagc tgcccttcgt gaattagagg aagaaacagc
    14521 ctatacaggg aaattagaac tcttgtacga tttttattca gctattggct tttgtaatga
    14581 gaagttaaaa ctatatttag caagcgattt gacaaaagtg gaaaatccgc gtccgcagga
    14641 tgaggatgaa accttggaag tccttgaagt gagcttagaa gaagcgaaag aattaatcca
    14701 atcaggtcat atctgtgatg ccaagacaat tatggctgtt cagtattggg agttgcagaa
    14761 aaaatagagg aggtcagtat gggtaaatct ttattaacgg atgaaatgat tgaaagagct
    14821 aatagaggcg aaaaaatttc aggtcctcct ttgctagatg ataatgagga aactaagatt
    14881 ttaccaacct cttcttcccg ttttggttat gccaatccta aggatcatgg ttttagccag
    14941 gaaaccttga agattcaggt cgaaccatct attcataaaa gccgtcgtat tgaaaatacc
    15001 aagagaaatg tcttcaattc taagttgaat aaaatcttat ttgcggtcat ctttctcttg
    15061 attttgcttg ttttagcaat gaaacttttg taatagaaaa ggaattgaaa tgaaaatagg
    15121 aattattgct gctatgccag aagaactggc ttatctggtc cagcatttag ataataccca
    15181 ggagcaagtt gttttgggga atacctatca tacaggaacc attgcttctc atgaagtcgt
    15241 tcttgtagaa agtggaattg gtaaggtcat gtctgctatg agtgtggcga ttttggctga
    15301 tcatttccag gtggatgccc ttattaatac gggttcagct ggggcagtag cagaaggtat
    15361 cgctgttggg gatgtcgtga ttgctgacaa attagcctat catgacgtgg atgtcacagc
    15421 ttttggctat gcttatgggc aaatggcgca acaaccgctt tatttcgaat cagacaaaac
    15481 ttttgttgct caaatccaag agagtttatc tcaattggac caaaactggc atcttggttt
    15541 gattgttaca ggagatagtt ttgttgcagg aaatgacaag atagaagcga ttaagtccca
    15601 tttcccagaa gttttagccg tggagatgga gggggcagct attgctcaag cagcgcatgc
    15661 cctcaatctc ccagtcttag tcatcagagc tatgagtgac aatgccaacc atgaagcaaa
    15721 catctttttt gatgagttta ttatcgaagc tggacgtcgc tctgcccaag tcttgttgac
    15781 ctttttgaag actttagatt aagcggaaat ttgacagttt ttctagctta tgataagatt
    15841 taagtaaaga aaagctagaa aacgtttcag aggatattat gagtattgaa atgaccgtca
    15901 gtgagattgc agaggtctta ggattatctc gccaagcaat caataaccgt gtcaaagaat
    15961 taccagaaga agacacagat aaaaatgaca aaggggtaac agttgttacc agaagtggct
    16021 tgattaagct agaagaaatc tataaaaaaa cgatttttga agatgaacct gtcagtgaag
    16081 atgtcaaaca acgtgaactg atggagattc tagtggatga gaagaatgca gaaattcttc
    16141 gtctttatga acaattaaaa gccaaggatc gtcagttatc agaaaaagac gagcagatgc
    16201 gtatcaaaga ccgtcagatt gctgagaaag acaaacaatt agatcagcaa caacaattga
    16261 cccttcaagc catgaaggat caagaaaatc ttaagctaga gctggaccaa gcaaaagaag
    16321 aagtccaatc cactaagaaa ggcttttttg ctcgtttatt tggaggataa tcaaggagct
    16381 gtttaggtta aatgctaacc tgatggcttc ttttgtttgt gaatagtata gttgattaga
    16441 acagagacag tagaggagag gtacagaatg gaacgattag aagattacat tgcttttgac
    16501 ttagaattta atcagcacga aggacaaaca cacttgattc aagtatcggc agtgcgtttt
    16561 agagatggtc gggaaatcga tgcctatgat tcctatgttc ataccaatgt acctctaaaa
    16621 agttttatca atggtttgac agggattacg gctgagacct taaaagatgc tccaccagtg
    16681 gagaaagtta taaaagaatt ccaagagttt gtgggttctt tgctgatgat aggctacaat
    16741 gctgctaaaa gtgatttacc tattttagca gagcatggtt tagactatag ccaacagtac
    16801 aaggtggatt tgtatgatga agcttttgaa cgtcggagtt cagatttaca tggtattgcc
    16861 aatctcaaat tgcaaactgt tgcctcattt cttggatttc aaggtcagtc tcataatagt
    16921 ttagaggatg ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc ggatcaagct
    16981 agggaattgt tagagacaga aagtagctta tcaaacaatc cttttggtgg cttggacttg
    17041 tctcaattat ttgactagga gtgcctatga aacctgaaaa acctaaaaaa ttgggtctta
    17101 aacagattta cctcaatctt gataaaatcc tctttctatt tttcttgatt tttatgatag
    17161 tggagtattt gtgggtacca ttcaattcat ggttggctag cttcttatta gatcagacag
    17221 gttatctttt tatttcctat aacaatgtct tagccatcct tactcattct ccattgatta
    17281 gtctagcttt tttagccttg attgtaatta accttctggt tgcttatttt caaataggac
    17341 tcctctttat tggcgctcgt catctcctct ataatgaaaa gcgaaggcta attgagtata
    17401 tccgcaaggt tttccatgaa agttttggat ttatgaaaaa gctaacttgc gctaaagcct
    17461 tgtttatctt tttctatata gctatgcttt ttccttttat acggaaaatg ctgaagattt
    17521 attatcttaa taaaatcgtc attccagagt ttatccaagc ttatttagaa gatacatatt
    17581 ggatgtggtg gctgagcatc ctacttctat ctcttatctt tctctatgtc tctgtcagat
    17641 tgatgtttgc ccttccgaag attgtatatg atcagctgac tgttcgagaa gcagtgatgt
    17701 ttagcttgga gaaaaccaag aagagagtta ctttttatgc ttggaattta ttttacatct
    17761 tgctcaaagc acatttatta ttttatcttc ctttgattcc tttattattg gctcaaactt
    17821 tggtagatga tatcactcag agagagtctc tgattcttgg tattttgaat tttgtcgtga
    17881 ttaaaaatct ctattatatg gctctgactt attttttggt taaatttgtt tcatttttga
    17941 caggaaagga gctggatatg cttcctagga gagaaaaaga tcacatcgtg cgatggggtg
    18001 tcatgacttg tgccagtctt ttctttgcct tagaaggtta tatttatctg gaggctccca
    18061 tggttcatct acctcaactt atttctcacc gaggggtttc caatgcaaat gggattcaaa
    18121 atacagtaga gtccttggaa actacagcac aactcaaacc agacttggtg gagacggacg
    18181 tgcaggaaac aaaagatggg cagtttgtca tgatgcatga tgctaacttg aaaaatctag
    18241 caggtatcaa taaaagtcct caagacttaa acttggagga gcttaaaggg attgatattt
    18301 ttgaaaatgg ctaccagact aaaatttcaa gctttgaaga ttatctcagt cgagccaacg
    18361 aacttggtca aaaattacta attgaaatta aaaccagtaa aaaagatagt ccagacatga
    18421 tgaaccgctt tttagcccgt tatgctgcaa agctcaagat ttatggacat caaatccagt
    18481 ctttagacta ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg ccagtttatt
    18541 tcatcatgcc ctacaattct gtctttccta aaacaagagc gacaggatat actatggagt
    18601 actcaacctt ggatgaatat tttgtaagca aactatggac aacggatcag aaactttatg
    18661 tctggactgt caatgattca gaagctatca gcaaatctct tcacttagga gtagatggag
    18721 tgattacaga tgatttggaa aaagttcagc gggaaataga agtatcccaa gaagatccag
    18781 aatatacgga tttgctcttg aaaaaagcat tggaattctt tgaattttag taataaaaaa
    18841 gaggaacggt tgttcctccc atgataggta agtattcttg tgaatgcttg cttttttgtg
    18901 gttgcaatcc gtttacgaga attgtttgta ttgttcttgt ttcaatttac tttatagtgc
    18961 tttgaagttg gaatgctaca ctataacttc taaaatatta ctagaaattg ggaagatttt
    19021 taatttcttt tccgaataaa tagatagaag catcaaatct agtaaattaa attatacttc
    19081 ctgcgaaaca aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact
    19141 gatgcatgat ttaagcgtct tgttggtgtt cagcgtacca cttttgaaga gatgttagct
    19201 ggattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc
    19261 ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aataccgcac ttatgaagaa
    19321 attgcggctg attttggtat ccacgaaagc aacttaatcc gtcggagcca atggggtgaa
    19381 gtaactcttg ttcaaaatgg ttttacgatt tcaagaactc ctctcagttc tgaggacacg
    19441 gtaatgattg atgcgacgga agtacaaatc aatcgcccta aaaaaagaat tagcgaatga
    19501 ttctggtaaa aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa gtcaaggaag
    19561 aattgtttct ttggatatc
//
LOCUS       DAVFJR010000039        19305 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVFJR010000039 DAVFJR010000000
VERSION     DAVFJR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.040"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..382
                     /locus_tag="VU722_001720"
     CDS             <1..382
                     /locus_tag="VU722_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU1772649.1"
                     /translation="KGYEVQLALIATKPELSYLSTLIRYEELYAINPNQARATPKEHH
                     DFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSGEDTTSAATVLHDLLFGEWNTV
                     EKEMLKIGQERLWVINKELNNRGD"
     gene            384..1780
                     /locus_tag="VU722_001721"
                     /pseudo
     CDS             384..1780
                     /locus_tag="VU722_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1782..2477
                     /locus_tag="VU722_001722"
     CDS             1782..2477
                     /locus_tag="VU722_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772650.1"
                     /translation="MRDIVIKFLQNNHFNQLDTDFDFYTNSQKSEYFIVSQYSPDELN
                     NFFDDDKTSQVIKEFERVSLTPEHENIKKNTSMFILVEVDDLKEVFEDEKVQRSILLI
                     EEDYYYFRKFIILYTRNGLLDLRDKETNEILYTYLESNIDAFEDDMFFSESYFMAMEI
                     GVKLPFFTLPKRNDIYQSIESQYQDDKDELDNRLLDFYTKNTDEKLSKSLKDISTDDD
                     NISDLLQIGELLQ"
     gene            2474..5122
                     /locus_tag="VU722_001723"
     CDS             2474..5122
                     /locus_tag="VU722_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU1772651.1"
                     /translation="MKIKKILIKNFKNIKETRIIDFQENVTLFVGPNGFGKTTIFDAI
                     ELSLTGKIRRIEESDYSDGRSSFSAPYFQNNPNQNTFIELMLTNDEGNSLIVSSLYKS
                     SMNTEGSNVPKFSFSKFQRRVRVGPGISFQSDEDFEGSSERDIQKDISQFLGYESEDY
                     SLGDTFDLFHYIQQDETAYYLKQKEKDRKEQLNFLLNIGNYVNRKNRLERLRSTLSSS
                     EKELRAKKGKLKNSPIKNNILYSKLSLRADTDFAFNNKSIIFDEELSNESLNIYLSEI
                     TKLQEFRNSFSPKDYFLRKQSEQFEREVLDDKDFTIYLIVREILENQENIESIKQNYS
                     LISNEKNFSYFLLKNYLERQDLLENDSKLFKFGKRLKSLLDVEIAKIDIKSIENSLNN
                     FTGWEFGRLWIEKFEPKLTEYKFKEGQLDDGTESINKLLEIRTRLKEHSTGNHSECIF
                     CGYDWGESENLLAAYEETTNQLRKNLTNFEIEVSNLVEELNQLKMELQNQIQMEQEKL
                     FVIPDDFLAAIRSISNYNFPESFSNLVVMNSEITPLPVDKSASLQEFENLKTELISSL
                     QEKLLIPNEVYGTFLRVVNKSVDFEKLLEKYSILAGESIREYEISFDLLPISLHKFEE
                     NKDRLLVFLGDLRSQIVFDYSKSLDSQNLFDKYFASKEKTFEDCTIESINQKREYIIN
                     QFELQSLTMFHQIEKRLQIIEQTITYLQDRVRELNNNIKSYQEQMIQKLKLPFYMYTA
                     KILQNYQQGMGVLLTTQNNSNIRFIANSNSEQDVMYQLSSGQVAVISFAFTLALNTTF
                     KISRGFKFLSIDDPIQDMDSMNVYALIDLIRHSLSDYQIIMSTHNDGSAMFIKYKFEL
                     FSDSEISNVGLKNIKNILLLDVEVSS"
     gene            5511..5870
                     /locus_tag="VU722_001724"
     CDS             5511..5870
                     /locus_tag="VU722_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772652.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            5880..6245
                     /locus_tag="VU722_001725"
     CDS             5880..6245
                     /locus_tag="VU722_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU1772653.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERISKSNCQNFSVYARKVLLS
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLNEFHGSY"
     gene            6232..8098
                     /locus_tag="VU722_001726"
                     /pseudo
     CDS             6232..8098
                     /locus_tag="VU722_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(8143..8997)
                     /locus_tag="VU722_001727"
     CDS             complement(8143..8997)
                     /locus_tag="VU722_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEU1772654.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDGFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLVNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIGKEEFSNCSYLISKIK
                     TLLDNKLNFYEQPVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            9077..9139
                     /locus_tag="VU722_001728"
     CDS             9077..9139
                     /locus_tag="VU722_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEU1772655.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            9220..9762
                     /locus_tag="VU722_001729"
     CDS             9220..9762
                     /locus_tag="VU722_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772656.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDLYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELKRT"
     gene            9759..10898
                     /locus_tag="VU722_001730"
     CDS             9759..10898
                     /locus_tag="VU722_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772657.1"
                     /translation="MMTRKVPNIEQMSQIECGFCCYLSILHFYKSKETLLDLRRDIEK
                     GRDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNK
                     VYIMDPSKGYVNYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKG
                     RLILTLLFSIISYLIILSIPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILAR
                     SMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVV
                     GGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSL
                     IYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSVE"
     gene            10961..11602
                     /locus_tag="VU722_001731"
     CDS             10961..11602
                     /locus_tag="VU722_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1772658.1"
                     /translation="MTIESGQRIALVGQSGSGKSTLLKILLGLYKIDTGKVLFDGINI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTKIIVSHRLSTIKDADIIFVMKGGKIVESGNHKYLMALGGEYYSLYTKRK"
     gene            11615..11785
                     /locus_tag="VU722_001732"
     CDS             11615..11785
                     /locus_tag="VU722_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772659.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            11819..12547
                     /locus_tag="VU722_001733"
     CDS             11819..12547
                     /locus_tag="VU722_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1772660.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            12540..13277
                     /locus_tag="VU722_001734"
     CDS             12540..13277
                     /locus_tag="VU722_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772661.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLTTVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            13290..14000
                     /locus_tag="VU722_001735"
     CDS             13290..14000
                     /locus_tag="VU722_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772662.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYVLHTLIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSITNLGIKLLVCIWIMG
                     FEFSLLPKLIKLKEQNLV"
     gene            14543..14764
                     /locus_tag="VU722_001736"
     CDS             14543..14764
                     /locus_tag="VU722_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772663.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15070..15384
                     /locus_tag="VU722_001737"
     CDS             15070..15384
                     /locus_tag="VU722_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU1772664.1"
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEARKNDKNE
                     VQLGCSPFDNKRLGIAPKNIVENLISISFSDIEGEKNGYIKDKEISRCIQRFKRKNLF
                     SN"
     gene            15311..16496
                     /locus_tag="VU722_001738"
                     /pseudo
     CDS             15311..16496
                     /locus_tag="VU722_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(16953..18299)
                     /gene="gdhA"
                     /locus_tag="VU722_001739"
     CDS             complement(16953..18299)
                     /gene="gdhA"
                     /locus_tag="VU722_001739"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU1772665.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKIYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            18745..19278
                     /locus_tag="VU722_001740"
                     /pseudo
     CDS             18745..19278
                     /locus_tag="VU722_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6950 a         2578 c         3418 g         6359 t
ORIGIN      
        1 taagggatat gaagtacaat tagccttgat tgcgacaaag cctgagctgt cctatctgag
       61 cactcttatc cgatacgaag aactgtacgc tatcaatcca aatcaagcac gcgcaactcc
      121 aaaagaacat catgatttca ttgtaaatca tctagttgat aatacacggc aattagaaga
      181 actagctatc tttgaaagaa ttcaaattta ccaacgagat agaagttgtg tatatgattc
      241 aggagaagat acaacttcag cagcaacagt tcttcatgac ttactatttg gagaatggaa
      301 cacggttgaa aaagagatgt tgaagatagg gcaggaacgg ttgtgggtga ttaacaaaga
      361 gttaaataat aggggggatt aagttggcga gttcaaacgt tgaccaaaat aggaatgcaa
      421 caccaagttg gagtggatat atccatcaag ggaaagtagg atttttagta gcgttaagac
      481 aattgaaaaa atgtattgat gataaggcgc ctgattacga gaattatgtg attagatatg
      541 aaaatgctga agattttgat attgttgata acaacgacaa agttatatct aggcatcaag
      601 taaaggcata tatagatggt acgtcaaggg aacaatattt aagatacaaa caagaaaata
      661 ttgtgaggtt gaggataaga gaagtaatca aaagatttgg aaagaaataa ttgatgagga
      721 aggatttcaa atccatcaat ttgatgggca aggacacata ctaactgtag aagttagtcc
      781 tgattcaaga tacttacacg ttattgtagc aataacagat ttcaatttat ctcggtatga
      841 gtatttaaag aaagacggtc gcagaaaaaa atatactgat aataattcat gtattcaact
      901 atatccatac aataaagaga acgatcttta tcattgtcca ctttctcagg atgataataa
      961 tgatacaatt agagattatt gtaaagctga aataaaagaa attttaaaat caaagggtaa
     1021 ttcattgaat gatagtgtct cacatttaga ccaagtatat ctcaggtatg taggttcttt
     1081 attggatcat agcattggac aagaacacag tgagtctggt tttccagaaa tatcctttgg
     1141 agaaatactt tccattattg aaacggaaac ttctgaagat gaagtatatg aaatgaaaaa
     1201 aaatttgacc tataggtggg aaaaatatca tggtgattat gcaagtgaca ttagagagga
     1261 agattttaaa cttatggatg aaataaataa tcatttactg tcattgacta aagatgagtt
     1321 ttatgaattt gtgagaatga tgttaccaca cgaaaattca gatgaaaaat ttttagaatt
     1381 gtttcgtaat gccccaatgg aggatatatt ttatgtatta ctggagaaaa ttaagggatt
     1441 ttcgtttaaa tcttacagtt atttagatga taatgagaag agctatagaa cttcattgat
     1501 tagtattcag gatagacctg ggataattgc aaaaaaaatt caagaaataa ttgacaactc
     1561 agaattttta aaagctactt ttaatcatga tttccttatt aatagagata tagatgagtt
     1621 gcatattggg aatagaattg atgaatttga tggcatgcta gataatagat atcgtgaaga
     1681 atggaataca ggagtacaac ataatatatt taaaccgaat atggaattca ttagcattga
     1741 gaaagtaaaa gaaaagaatt tgagtgtgcc ggaggactaa tatgagagac atcgttataa
     1801 aatttttaca aaataaccat tttaaccagt tggatacaga ttttgatttc tatactaact
     1861 cacaaaaatc agagtatttt attgttagtc aatatagtcc tgatgagcta aataattttt
     1921 tcgatgatga taagacttca caagtaataa aagagtttga aagggtatct ctaacaccag
     1981 aacatgaaaa catcaagaaa aatacttcta tgtttatttt ggtagaagtt gatgacttga
     2041 aggaagtatt tgaagacgag aaagttcaac gatcaatttt attgattgaa gaggactatt
     2101 attattttag aaagttcata atattataca ctcgaaatgg gttattggat ttacgagata
     2161 aagagactaa tgaaatactc tatacttact tagaatctaa tattgatgct tttgaagatg
     2221 atatgttttt tagtgagtcg tattttatgg ctatggaaat tggagtaaaa ctaccatttt
     2281 tcacactccc taaaagaaat gatatttatc aaagtataga aagtcagtat caggatgata
     2341 aggatgaatt agataataga ttattggatt tttatactaa gaacactgat gagaaattat
     2401 caaaatcact aaaagatatt tctaccgatg atgataatat ttctgattta ctacaaatag
     2461 gagaattatt acaatgaaaa tcaaaaaaat tttaataaaa aactttaaaa atataaagga
     2521 aactagaatt attgattttc aagagaatgt aactttgttt gttggaccaa atggatttgg
     2581 aaaaactaca atttttgacg caatagagtt atcattaact gggaaaattc gtcgaattga
     2641 agagtccgat tatagtgacg gtagaagtag ttttagtgct ccatattttc aaaataatcc
     2701 taatcaaaat acattcattg agcttatgtt gacaaatgat gagggtaatt ctttgatagt
     2761 atctagtctt tataagagta gtatgaatac tgagggcagc aatgtaccaa agttttcatt
     2821 ttctaaattt caaagaagag ttcgggttgg tccaggaatt tcatttcaat ctgatgaaga
     2881 ctttgagggt tcgagtgaaa gagatataca aaaggacatt agtcagtttc taggatatga
     2941 atcagaagat tatagcttag gtgatacttt tgatttgttt cattatattc aacaagatga
     3001 aacagcttat tatttgaagc aaaaagaaaa agatagaaag gaacaattga attttctgtt
     3061 aaatattgga aactatgtta ataggaaaaa tagattagag cgtttaagaa gtactttatc
     3121 ctctagtgaa aaggaactaa gagcaaaaaa gggtaaacta aaaaattccc caattaagaa
     3181 caatatccta tattcgaaat tatctcttag agcagatact gactttgctt ttaacaataa
     3241 gtcgattatt tttgatgaag aattgtcaaa tgaaagttta aatatatatc tatcagaaat
     3301 tactaaatta caagaatttc gaaattcatt ttctccaaaa gattacttcc ttagaaaaca
     3361 aagtgagcaa tttgagcgag aggtgctgga tgataaagat tttactattt acttaatagt
     3421 tagagaaata cttgaaaatc aggaaaatat agagtcaatt aaacaaaatt atagtttaat
     3481 ttcaaatgaa aaaaatttct catatttttt acttaaaaac tatcttgaac gacaggactt
     3541 gttggaaaat gatagtaagt tgtttaaatt tggaaaaaga ttgaagagct tacttgatgt
     3601 tgaaattgct aaaattgata tcaaatcaat tgagaattct ttaaataatt ttacaggatg
     3661 ggaatttggc aggctatgga ttgaaaaatt tgaacctaaa ttaacagaat ataagtttaa
     3721 agaagggcag ctagatgatg gaacagagtc gattaacaag ctactcgaga taagaactcg
     3781 tctaaaagaa catagcactg gaaatcattc ggaatgtata ttttgtggtt atgattgggg
     3841 agagagcgag aatttactgg cagcctatga agaaacaacg aatcaactac gtaaaaattt
     3901 gactaatttt gaaatagaag tttcaaattt ggttgaagaa ttaaatcaat taaaaatgga
     3961 gttacaaaat cagatccaaa tggagcaaga gaaactcttt gttattcctg atgatttttt
     4021 ggcggcgata cgatccataa gtaattataa ttttcctgag tcttttagca acttggttgt
     4081 aatgaactca gagattactc ctttgcctgt tgataagagt gcttcgctac aagagtttga
     4141 gaatttgaaa acagagttaa taagttcatt gcaagaaaaa ctattgattc caaatgaagt
     4201 ttatggtact ttccttagag ttgtaaataa gagtgttgat tttgaaaaac ttttagaaaa
     4261 atattctatt ttagctggag aatcaataag ggaatatgaa atttcttttg accttttacc
     4321 catttccttg cataaatttg aagagaacaa agacaggtta ctagtatttt taggggatct
     4381 tagatctcaa atagtatttg attattctaa aagtttagat tcacaaaatc tatttgataa
     4441 atactttgca tctaaggaaa aaacttttga ggactgtact atagaaagta tcaatcaaaa
     4501 gagagaatat attattaacc agtttgaatt acaaagttta acgatgtttc accaaattga
     4561 gaaacgtctt caaatcattg aacaaacgat tacatatctt caggatcgtg ttagggaatt
     4621 aaataataat ataaagtctt accaagaaca gatgattcaa aagttgaagc ttcccttcta
     4681 tatgtacact gctaaaattt tacaaaatta ccaacaagga atgggagttc tactaacaac
     4741 tcaaaacaat tctaatatca ggtttatagc aaatagtaat agtgagcagg atgtgatgta
     4801 tcaattgagt tctggacaag tagctgttat ttcgtttgct ttcactttgg cactaaatac
     4861 tacatttaag atttcaagag ggttcaaatt tttatcaatt gatgatccga ttcaagatat
     4921 ggattctatg aatgtatatg ctttaattga tttaataaga cattcattat cagactatca
     4981 aattattatg tctacacata atgatggtag tgctatgttt ataaaatata aatttgaact
     5041 attttcagat tccgaaatat caaatgtagg gctaaaaaat ataaagaata tcttattatt
     5101 ggatgttgaa gttagcagtt gatgagacta tatatattaa tggaaatata aaaaacatgg
     5161 tttcattaag acggtatttg agagccttgg ctttcttttt tcttaccatc atttttcatg
     5221 ttgtgatact tttttcaaat ttaccttgct atcctaatat cattactaag aaaatcaagc
     5281 cttaattttt cactgggggt ttgggggcgg agccaccaag ttatcttatc gttggctgtc
     5341 aaaactagaa ggttttgaca ggctggcgat atgatttttg ggatattgtg gacacaatat
     5401 ctgagctcgc aaagaccgaa caaggagaga ctgaggtctt taggaatcgt actgacaatg
     5461 tgaggcagcc ttacattgtc agacaagtat aatgttgaaa ggatggtaag atgggacaag
     5521 aaattaagtt aatccgtaag caatttagaa tcacgagaca agaagaaaaa cagataaaag
     5581 aaatgatgag ggaacaaaaa gtggatagtt tctcagaatt tcttcgtcaa aatttattga
     5641 aaaagaatta tcaggataga atttttgaaa gttggttctc cctttggcag tctcaaaagt
     5701 ttgaacagat tagtcgagat gtgtatgaag ttctggttgt cgcaagagaa aatcatcaag
     5761 tgactcaaga gcacgtctca atcttattga cttgcgttca agaattgatt gcagaagtga
     5821 atcaagtaca gccactcagt cgtgagtttc gtgaaaaata tatgggttag gaggatgtaa
     5881 tggtttatcg ctatcgtacc aatctcaaaa aagtatttct aactgatcca gaattacacc
     5941 aattgaatga acggatttct aagagcaatt gtcaaaattt ttcagtctat gccagaaaag
     6001 ttttgcttag tcccaatatg tcatttgtca cgattaacac tgatacttat gaccagttag
     6061 tttttgaatt gagacgtatt ggaaataaca tcaatcaaat tgcgcgtgcg attaatcaaa
     6121 gccatctgat ttctcaggac caattacaag aattgagtaa aggagtcgga gaattaatta
     6181 aggaagtgga caaagaattt caagtggagg tgaaaagact gaatgagttt catggtagtt
     6241 actaaacact ttgcgacgca cggaaaaaaa atatcgtagg cgtttgatta aatatatcct
     6301 caatccagat aaaacagata atctaaaatt agtatctgat tttggcatga gtaattactt
     6361 agattttcct agccatgcag aaatggtaga aatgtacaat gttaacttta ctaataacga
     6421 caagttgtac gagtccagaa atgaccgaca agaaaaacac taacaaacta ttcatgccca
     6481 tcatctcatc caatcatttt ctcctgaaga taatctgaca cctgaagaaa ttaaccgcat
     6541 tggttatgag accatgatgg aattgacagg aggtcgtttt aagtttatcg tagcaactca
     6601 cacagacaaa gatcatgttc ataatcacat cctaatcaac gctattgacc gcaattcaga
     6661 taaaaagttg atatggaact atgccttgga acgaaacctc cgtatgattt cagaccgtat
     6721 ttctaaaatg gctggtgcaa aaattattga gaaacgttat tcctatctag attataaaaa
     6781 atataaggaa tctagtcata aatttgaatt gaaacaacgt ctttattttt tgcttcagca
     6841 atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc agattgattt
     6901 tagtcaaaag catagccgtt ttttgatgac agatagaacg atggtaaaac caattcgagg
     6961 tcgccaactt agtaaacgag atttatatga tgaagacttt tttaaaacat attttgccaa
     7021 acaagagatt gaaagtcgtt taaaattttt actaaagtct gtttattcat tagaagaatt
     7081 gcatgtaaaa gctaaagagt tgaatctaac catcgagtta aaacagaaaa atgtgatgtt
     7141 taccctagaa gaagatggta aaaagataag cctgagtcat aaaaaaatta gcgataagaa
     7201 attgtacgat gttcaatttt ttaatcgtta ttttgaagat agagaagtta gagatattca
     7261 agtattagaa aatcttcagg aagattttca gacttttcga gaggagcagc ataaggagaa
     7321 agtctccgct gaagaaatcg aggaagcctt caagaaatac aaggaaaaac gagatgctat
     7381 ccatgagttt gagattgaac ttacggataa tcagatagag aagttggttg atgatggtgt
     7441 ctatatccag gtttcgtttg gtatcaaaca gagtggactc atctttattc ttaactacca
     7501 gctagatatt tttgaggaag acaatcataa aaaatataaa gtctacattc gagaaacgtc
     7561 ttcttacttt gtctataata aagaaaacat ggataataat tgtttcatca agggtaggac
     7621 cttaatcaga caattgagca acgatagcca aaaactcccc tatagacgac caactttaaa
     7681 aagtcttcaa gagaagattt ctgaaattaa tcttatgatt gaactatcta acacgaacaa
     7741 acaataccaa gaaatcaaag atgagcttgt attagaaatt gcagagattg atatgcagct
     7801 agaagaaacc caagaaaaaa tcgccacctt aaacaagatg gcggaagtac ttatcaattt
     7861 gaagagtgaa gatcatgaga ctagaaaatt agctaagtat gattttgacc aaatgaacat
     7921 gacggaatca ataatgttag atcgactcaa tacagatatt ttaaaattac aacaggaact
     7981 tggtaatgaa attaataaat atgaggagat agctagaaga ttggatttgt ttgtgaaaat
     8041 tattaatacc aataaattta cagttctaaa atttcacgag aatgccttac tagaataata
     8101 ttatttacga ctaattagtt aaaagataga gaataatttc atttattttt tgtttactag
     8161 tttattaaaa tggtcagtat agtgtaattt taacttatct tctcctaaaa tatcgaagac
     8221 ttgtatggct tgtttcattt tttcaattcc actggttgat tggcaacgtt taaattcaaa
     8281 gtaaccagtt gcatagagaa aaactggttg ttcataaaag tttagtttat tatccaacaa
     8341 tgtctttatc ttactaatta aataggagca attagaaaat tcttccttac caatgcttag
     8401 aataaagcaa ttaatagcaa gctgagagac aatctgctta ttagttttat tcagagatga
     8461 gtaaatatag ttatttaaca tctctttagt taataagaag taggagttgt agttaattgt
     8521 gcgtacacag ttaactaata aaatgatttc ataatagccc catttttcaa ctttgaaaag
     8581 atagtctgtc agatgaagaa gctcttcatc tgatggaatg atgttcgaat ccattgtgtg
     8641 taaaatagat tttaccattg ttttctcaaa agaatttaga gtgtaatcag aagtatcaga
     8701 aagtagacat gctatattat tgatactttg tgatgaatat tgcttacgaa tgtactgtac
     8761 tagattagca aatgattcgg aactggtata gtcgtcattg tgtaaaacaa ggaacccatc
     8821 caaagtaata tgtaatttgt ctaaaatatt gattagtcga atacaagata tctctgactc
     8881 cccacgttca aaacgagata tttgtgattt tgaaagatgt tcatctgcta cagagcatag
     8941 actaatttgt tttcctttac gaacttttct aagtgtgatg ccaagttttg atttcataat
     9001 ttcccatttt cccaacaaaa attaaatccg tttttattta ttgtacaata aataaaaacg
     9061 gaaaggaagt ccaagtatga agaaaatttc aaaattttta ccgattttgg ttttggtgat
     9121 ggatattatc atcatttaaa aaagtgtatt aattattgta tttcacaatt agataatata
     9181 acagtaacag gtttagcaca cggttattct ggagtagcaa tgtcattatc atattattat
     9241 gaaattaatc ctagtacaga tatattaaaa tgtatagagg aattactata taaagaagat
     9301 aaatgtttca ataatatatt aaaaaattgg aaagacataa gaagaaatca taatgattcc
     9361 tttcctaatt tttggtgtta tggagctccg ggcattttgt tagctagaaa agaaattttc
     9421 gataaaacta atattgggaa taatgattta tcaataattg aaaatgtatt aactaatgta
     9481 gaaaaaataa gagaattgaa tttatgtcat ggttctgtag gtactatcag ttgtcttgat
     9541 gcaatattga aagatgaaga aaacctatta ataaaagaat ctatagattt gtattttgat
     9601 aatgtcgttt ctcaggttat caaaccagaa ttaagtacgg atttgaatac tatgaataca
     9661 ttttctttta tgctaggagt atctggagtt gtctatgaaa tatctcgaaa acaagatgat
     9721 agattactga atgttttatt actagagtta aagaggacat gatgactaga aaagtaccta
     9781 atattgagca aatgtctcaa atagaatgtg gtttctgttg ctacttgtcc atactacatt
     9841 tctataaaag caaagagaca ttactagatt taagacgtga tatagaaaaa gggagagatg
     9901 gttatagtat aggtgacttg aaacagttat tgaataaacg aaattttgat actggttcat
     9961 atcaagttaa agatgtaaat aaaattagtg aacttccgtt accattaata gcattttggg
    10021 ataatcaaca ttatgtagtt atttacaaag taaaaaagaa taaggtctat ataatggatc
    10081 cttctaaagg atatgtaaat tatgagttta aggagttttc aaaacatttt agtaatatag
    10141 tactgctatc atttcctaac gaaaattacc aatctttgaa gtcacagttt ccttcaccat
    10201 ggataagagt attctctagt ttttcaaagg taaaaggtcg attgattttg acgttgctat
    10261 tttcaataat aagttactta ataatacttt ctataccagt aatgacttca aagtttatta
    10321 attctgcatt aggtaataca ttttcttttc aaacctcgtt tttaatttta ttttctctac
    10381 tttgtttgta ccttatttct atcttggcta ggagtatggg aattctattt tctaatatat
    10441 tttttagtag agatattgaa agttttacat ttaagcattt gcttaaacta ccatatagtt
    10501 tttttgaact cagggcaaaa ggagatattt tatacagaat ttctagtctt agtggtttta
    10561 gggagctatt tactaaccaa gttgttgggg gagtagtaga tattgggact attctaagtg
    10621 ttgtaatata tatgtttctt agttcaaaaa cattatcaat tatagctctt atattgagtt
    10681 taatcaattt tttgtttctg tttagtacta gaaaaataat gtatgatacg gttaatagag
    10741 aattacaaga acaatcattg atttactcag tagaaacaga agcattaaat actatttctt
    10801 caataaaaat atcgggatta gaagatgaaa tatatgaaaa ctggtctaag tatttaaaaa
    10861 atgtattgac aaagtataaa aaacgaagtg tagaatagat attaaggacc tatctttctc
    10921 ttattccaaa gactcagctc ctgtaataga aaatttaaat ttgactattg agtcaggaca
    10981 gagaattgca ctagtcggtc aatcggggtc aggaaaaagt acgttattaa aaatactatt
    11041 aggattatat aagattgata caggaaaagt tttatttgat ggtataaata ttaatcaaat
    11101 agataaaaaa atattaagtc aaaatttagg agtagttcca caagattcgt ttttattgaa
    11161 cagaagtatt cttgataaca taactttaaa gcacgaagtt acttcacaaa agatagagga
    11221 agtttgtaaa gcagttcaaa tctatgatga aatcatggct atgccgatga aatttaatac
    11281 tatcatctca gagatgggtt caaatatttc aggtggtcaa agacaacgga tagcactggc
    11341 acgtgcatta ataaataatc ctagtattgt aattttagat gaagcaacta gtgcattaga
    11401 cactattaat gaggaaagaa taacaaagta tataaaaagt cagggctgta ctaaaataat
    11461 tgtatctcat agattgtcaa cgattaagga tgcggatatt atttttgtaa tgaaaggtgg
    11521 taagattgtt gagtcaggaa atcataagta cttaatggct cttggtggag agtactacag
    11581 cttatataca aaaaggaaat gaggtgtaaa gaaaatgaag aaagtaaatg aatatgtaat
    11641 ttcaacagca gcctcactag gggtgatgat tggaatagta tttgcaattt ttttagattt
    11701 tccagttgaa tatggtattt ctttaggatt gttgaatgga atagtattgg gttcgctgat
    11761 tttttacaaa aacaataaga attaagcaca attttttgct gtaaactaag gagtagagat
    11821 ggctatagtt gaaattataa atctaacaaa aagctttaaa gatattgaag ttattcataa
    11881 cacttcattt tatttaaata agggaaaagt atatggtttt gttggaccaa atggggctgg
    11941 aaaaactaca attatcaaaa tgattctagg gattttaaaa ccagattctg ggaaaataac
    12001 tatttttaat caaaccgtag aacagaattc cgaaaatata ttatctagga taggattagt
    12061 tttgggacct tcattttatg gtcatcttga tgcttataaa aatttgaagt taatagcaaa
    12121 tatgaaaggg cttagtttag atactgaaag acttaatgaa tatctatcaa tggtaggatt
    12181 aaaagatgtt aaaaagaaaa aagtgaaaaa tttttcaatg ggcatgaaac aacgtctaag
    12241 tatagctgca tcattgttag gtagtccaga aatattaatt tgggatgaac caatcaatgg
    12301 acttgatcca cagggtgtaa ttgaaattag aagtttaatc cgttttctac aggagaaaaa
    12361 aggtattaca tttttaatat caagtcatat tcttagtgaa ctggataaag tgatatctga
    12421 tattataatt ataaattatg ggaaagttga attttttggt tcttgccact accttttaca
    12481 aaagtataat tgtcgaaatc tggaagaagc ctacttagct tgtttagctg gaggtgaata
    12541 tgattaaatt agagtttcta aagcagaaaa aaagcatctt atggtttgtt cttatttttc
    12601 caataattct gaatgctttg ttatatatag acttaacttt taggtatcga ggttatttat
    12661 tggtgcatca aaatgaactt gctttatcta attggcagtt aatttttaaa gaacaaacaa
    12721 tattttattt ttctgaacta ttttatttag ttctatcttt aataatttac gaagtgtttg
    12781 cagtagaatt taaaaatgat gcatggttaa ccgtaatttc attgccattt agaaacaagt
    12841 acacaataaa ttctaaatta ctcactacag tggtttacac atttactttt tggttgtctg
    12901 attatattag cttatacgtt attgggaagg ctattgataa cagtttagag attggtttga
    12961 ttttcttttt aaaaacattt accattcaat taatttcctc gttgatgata atgttattat
    13021 attttctaac tttagtactt ataaggaaaa tttctggaat aataccaatt ggtattataa
    13081 tgatgatttt aacaattagc atatactaca acgattataa ttttaagatt tacttaccat
    13141 ttacttatct ttctcatgct tttagagtga ctgaaagtca attttatatg attttactat
    13201 ctaatataat aatcatcgta cttttttata tattaattcg taaattgaac gaaagaagtt
    13261 ttgagatgaa actttaatag gtaataaaaa tgaagttact taaaaatgaa ttgattaaga
    13321 gtaaaatatt tttatttatt attgttgaca tctgtattca gattctagtc attctagcta
    13381 taaaaacata tattttagat atttcggcac tatactcaga gcttgattat aataagtatt
    13441 ggtatgtttt acacacttta atatatatgc caatgatttt tcctatacaa attttgtatc
    13501 aaaatctaag agaggcattg attgaagata ataataatgg ttggaatatc atggtgatta
    13561 acactaataa tctcgtgaaa atcatctata taaaagtaac gataaatatc gtgagatgtt
    13621 ttatttgtta ttttgtttat acaatttttt ctttaattca attaggtggt atgggaactg
    13681 atatgttatt aaccaatata atatttccca atataatgtc atttctttta tttttaccta
    13741 tagctatctt tatgcaaatt tgctgtataa gatttgattc cattttagca aaggccttac
    13801 ctaatatttt gctgatactt attgttttaa tcacgtttca gagtgattgg aatatattta
    13861 tacctgcaac ttattattat acagaaattc agtcaattac aaacttaggt attaaattat
    13921 tagtttgtat ctggattatg ggatttgaat tttcccttct tccaaaacta ataaaattga
    13981 aagaacaaaa tctagtttaa atgttgctcg aaaattaaat aattgaatac gattaacaat
    14041 gaaacaatac aacgtgagtc atgacttcaa agtaattgat tttatgattc tggtttctta
    14101 cgcttaatta agcaagttgt attcacttta tcaaattgtt attactctaa aaagcgtcta
    14161 acagctatag agtgtctgtt tgcttctctt tacttttatt ttaaataatt cattaacctt
    14221 ccgtaagtgc ccaataataa ggtgtgttga agaagtctga gataaaatag ttctcagtca
    14281 caaaaaaaac tatagattcc cattggtgaa cagctccctg tcaagtagac agtaaaataa
    14341 tataaaatct taagcgacct gattcctgaa ttccagtgga gtcaggttgt tttttaaccg
    14401 tctttcttaa tattgtctta cctataatag atatgcttat gaaaagtgtt taataaatta
    14461 attttagttc aaaatgtcca atttggacac tttgaatgat ttcttagttt tatatattat
    14521 acttttctca ggagaaagct agatgtacag acgtttgaga gatttgaggg aagatcacga
    14581 tttgactcaa aaacaaatag ctaaaatact ttcgtttaca aactcagctt atgctaaaat
    14641 tgaacggggt gagcatacgt taacagcaga tgtattggta actctctcaa acttttacga
    14701 tgtcagtaca gactacctat tgggattgac agattttcct gataaaattc gctttagaaa
    14761 ataatctcct caatttcata gagtgtgaaa atgaggggat tttttatttg ttctttgaaa
    14821 attaaatagt tcaaaatggt actttcctca tttgtggagc aaatttgaat ggctcgccat
    14881 gataagagcg attttaaaac catcaataaa atagagcgat actttatatg ccatgataca
    14941 aatgatatac aatgatactt ctgaccgttc aggctgccaa cgtaaaagag cagcaagtga
    15001 aattcttatg atgacttcat cagtcatgcc atggaggtga aaaaatctaa gaaaggaagt
    15061 agtaaaatca tggaaacagt aaactataaa gatttagttg cgattggttt tccagagcac
    15121 acatctagaa atattattag acaagcaaaa aagattgctg taaaaaagtt tgaagaagct
    15181 agaaaaaatg ataagaatga ggtacaatta ggatgttcac ctttcgataa taaaaggtta
    15241 ggcattgctc ctaaaaatat tgtagaaaat ttaattagta tttctttttc agatatagaa
    15301 ggtgagaaaa atggttatat caaagacaaa gaaatatcaa ggtgtataca aagattcaaa
    15361 aggaaaaatt tattttcaaa ttgaattagg agttgatcca ataactggga aaagaattca
    15421 aaagaaagga aggaaaaatc aacagggact accgtttaat tcttttaagg aagcatatga
    15481 agagatactt cgtctaaaac atgaatttgt gaactctact attaataata gttttctaac
    15541 ttttagagag tttatggaag agatttattt aaaatattat caacaaaaag ttcaatctgt
    15601 aacttatcag accgctttac cacatcatca gttatttatt aagcaatttg gtagtaaaaa
    15661 attatcagat attagtacta ttgactgtga aagatttcgc ttagctatta tagacaagta
    15721 ttctagtaat tatgctaaaa atatgtggta gatttaaagc atgtctgggc tatgcagaaa
    15781 gattgggtta tattgataaa gttcctttta aaggattaga taatcctaga ggaaagtacc
    15841 ctgatacaaa attttggaca tttgatgaat ttaagaaggt aataaactct tttgatatta
    15901 gtgagtatga gggactccat aattgcatga cgatctggtt atattttatg actggtttaa
    15961 gagttagtga gggtattgct cttaaatggg aagatattga ttttgaacgt aaatggattc
    16021 atgttcattc gacaattgag aaagataaaa acggtgtatg gtatgttaaa caacaaacaa
    16081 agacagtagc aggggatcgt aaaattgatt tagatgattt tacgattaca atacttaaaa
    16141 aatggcgaga agttcaaatc aagaatgatg ataaagatta tgtaatatca cgttttggtg
    16201 cccccttgtg taagtctaca atttctagga taataaaaag gcatgctaag attactggtg
    16261 taccagaaat tacggggaaa ggattaagac atagtcatgc atcttatctt ataaatgtgt
    16321 tacataagga tactttatat gtttcatatc gattaggaca cgctgataag tcaaccacgt
    16381 tgaatacata tagtcactgg tattattcag gtgattcaac aatttcagaa gagattacaa
    16441 acagtttaga taatcttgga ttatcaattt acctaccaaa ttcctgccag agttgaaaat
    16501 tgaggaatta acccactaat actgggagaa aataggattt gcaaattgtt actcttaaat
    16561 aatagagcaa ctacagtagt agcttaaaaa catgattaaa tcgctatttt taggagtagc
    16621 ggtttttctt tttgtttaat actctttgaa aatcaaattc aaaccacgtc agctttgcct
    16681 tgccgtactc aagtacagcc tgcggctcgc ttcctagttt gctctttgat tttcattgag
    16741 tataaaaagg gtcaagtaag tatagtaaat tgaaataaga tatgaacaaa tcgattagga
    16801 aagtcaaatt aatttctaga aatatgttag aaattggttt gaattccgca atcaatttgt
    16861 tcagttttta tttcatttaa ttagaatttc ccaactgtct aactcaacta aaaatcccca
    16921 atcgtagtga ttgaggatta agcaaataaa tcttaaacaa taccttgggc aatcatagcg
    16981 tttgctacat tttcaaatgc agcaatattt gctcctgcaa gatagtcttt atcaagacca
    17041 tatgtttctg aagttgtttt agctgtgttg aagatgtttg tcatgatgtc tttgagacgt
    17101 ccatcaactt cttcacgagt ccatgagaga cgaaggctat tttggctcat ttcaagggct
    17161 gaaacggcta caccaccagc gttggcagct ttggcaggtc cgtagaagat accattttct
    17221 ttgtagattt tgatggcatc aaggtcgctc ggcatgttgg caccttcaga tacacagata
    17281 acgccttgag caaccaaacg tttagctgct tcaccgttga tttcgttttg agtagcacat
    17341 ggaagcgcaa tatcatagtt tccagcgtaa gtccatacag aaccttcgtg atatgttgca
    17401 gttgctttct cagctgcata ctcagtcaaa cgagcacgac gtttctcttt aacatcaacc
    17461 aaaagatcga agtcgatacc attttcatcg atgacataac cgtttgagtc agatacagag
    17521 atgacagtag cgccaagttc agtcgctttt tgaagagcgt attgagcaac gttcccagaa
    17581 cctgaaataa cgactttctt accagcaaag ctgttgccat ttgccttgag catttcttca
    17641 gtatagtaaa ccaaaccgta accagttgct tctggacgaa tcaagctacc accaaatcca
    17701 agaggtttac cagtcaagac accagcatca aattggttaa ggcgtttgta ttgaccgtaa
    17761 aggtaaccaa tctcacgtcc accaacaccg atatcaccag caggtacgtc aagtgatggt
    17821 ccgatgtgtt tttgcaattc agtcatgaag ctttgacaga aacgcatcac ttcagcatct
    17881 gttttacctt taggatcgaa gtctgatcca cctttacctc caccgattgg aagtccagtc
    17941 aagacgtttt taaagatttg ttcaaatccg aggaatttca agatcccttg gtttacagtt
    18001 gggtggaaac gaagtcctcc tttgtatggt ccaacagctg agttgaattg aacacggtaa
    18061 ccacggttta cttgaatttt tccatcacgg tcaacccaag gaacacggaa agaaattacg
    18121 cgctcaggct cagtaatacg tgccaagata ttttcttcga tatactcagg gtgtttttca
    18181 aatacaggtt ccaaagtgtt gaaaaattct tcaacagctt ggaggaattc agcctcgtgc
    18241 ccgttacgag cttttacagt ttcaaacacg ctttggatat attctttagc agatgtcata
    18301 tcgttctcct tttgttgtca tattttatta catgagctat tatagcagaa tttttttaaa
    18361 ctgtaaagag aaaaacaaaa attttctaaa aattctttca atttgttttt tggtttcggc
    18421 ttttcttgaa ctgataaaaa tcaaaccttt ttcttggaaa tatctttctc aaagagaaaa
    18481 tcttaaagta tgctataaga aaagaaaatg tttagcaatt cagaaatcac ttgttaattt
    18541 atccgtgata tgttagattt gccagtaaaa ctatgatcat tttggaggaa agcaatattt
    18601 acatctcctt attcatggca ggatttttta tacaagtata gatgtcttgc tggagttgaa
    18661 tcatggaacc caagcggtta ttgagattta gaactatcat cagaattttt tcattagact
    18721 tgttcggtaa ccatacagta ctatactatc catgaacaag acctagaaaa agtagcctta
    18781 tttcttaaaa gttttaatag tttaaagcac ttagcacctg tttatattga tgagacagga
    18841 ttcgatactt atttttatcg aaagtatggt tgttctttaa aaggtcagtt aataagaggt
    18901 aaagtatctg gaagaatata tcagaggatt tctttggttg cagggctaac aaatggtgag
    18961 ttaatcgctc caatgactta cgcagagacg atgacgagcg acttttttga agcttggttt
    19021 cagaagtttc tcttaccaac attaaataca ccatcggtta ttattatgga taatgcaaga
    19081 ttccgtagaa tgggtaagct agaagtcttg tgtgaagagt ttgggaataa acttttacct
    19141 ctccttccct actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
    19201 cacctcaaaa gggtattacc aagttgcaat accttttacg aggctctttt gtcccactct
    19261 tgtaaatgtc taagataaga gctatactag gtaaataaaa atctc
//
LOCUS       DAVFJR010000040        19022 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVFJR010000040 DAVFJR010000000
VERSION     DAVFJR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.041"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            175..813
                     /locus_tag="VU722_001741"
     CDS             175..813
                     /locus_tag="VU722_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU1772666.1"
                     /translation="MLNKMKVSFLLGLGGLAVMSFVVMMGYTIGSQSVTHHMQKQIQT
                     EAHKLLTQEKEKEKASVLSDELVKEFLTQYYTKGKLGENNNRIKLYMTDSAYKEEVAR
                     QEDSINQVYKDYMLDYRFETAQIYVNTEANEALAEVSYQVVYVSDVSDKAQKSTQTET
                     KSLKLSYTKMSDKFLVKQVTVWNGKLENLKEVSDGADSSIPDIQGTTTSETN"
     gene            852..1940
                     /locus_tag="VU722_001742"
     CDS             852..1940
                     /locus_tag="VU722_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEU1772667.1"
                     /translation="MTRIEAVKQKAILEVAESLGYSFKRLSGQVYEHPEHDSFRIFAD
                     TNTFKWFSRDIQGDVIDFVQLITGVTFKEALSYLETGDFEQTKMVEETYQPFRYYLRE
                     EPFYQARIYLNDIRGLSDDTINAFGRQGLLAQAHYQTKIFQESVLVFKSYSHHGQLEG
                     ASLQGLVKNNERHDRDYLKKIMKGSHGYVGMSFDIGKPERLIFCESVIDMMSYYQLHQ
                     NQLSDVRLVSMEGLKLSVIAYQSLRLVAEEQGKLEFLDTVKPSRLTHYLHAIQETTTF
                     FQTHPSLITLAIDNDGAGRDFCQKLSEKSLPIETDLPPLQELETKADWNDVVKSQKDL
                     SLKDMIQSAKLQVIRSNPPPRKNTALEL"
     gene            1994..2227
                     /locus_tag="VU722_001743"
     CDS             1994..2227
                     /locus_tag="VU722_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772668.1"
                     /translation="MSVIERLAERVARQEEKVAKETEKLGTYREQLQAAMYSIFVKRQ
                     QSSHLTFDEALNQAFGKQENHSQVIENRNEETE"
     gene            2224..2619
                     /locus_tag="VU722_001744"
     CDS             2224..2619
                     /locus_tag="VU722_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEU1772669.1"
                     /translation="MTKDWTFDQSLDDNTPTSSTEERAKIAALFHKEEKEETGEVNYV
                     AAFEMEQQKAKEKSVSKPKVQEQSTPKEVPSSTITSDYKQHLANVMAQNNEDILQSQK
                     KIEELNQLIDDKNKQNKKLQAISEAIDDL"
     gene            2665..2952
                     /locus_tag="VU722_001745"
     CDS             2665..2952
                     /locus_tag="VU722_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772670.1"
                     /translation="MRLFKKQTHNQDSFKRLIHRLSGMSETDLHKVNQLLDVVFDATS
                     QTIHEETMTPKDMPKEPILDETITEAKNKLNTEQLEKRIEQFRQAKKPKSG"
     gene            3021..3497
                     /locus_tag="VU722_001746"
     CDS             3021..3497
                     /locus_tag="VU722_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772671.1"
                     /translation="MIGENIKSLRRTHDLTQPEFAKIVGISRNSLSRYENGTSSVSTE
                     LIDRICQKFNVSYVDIVGEEKMLTPVEDYQLTLKIEVIKERGAAVLSQLYRYQDSQGI
                     AFDDETNPWILMSDDLSDLINTKIYLVDTFDEVERYNGYLDGIERMLELARHQVVA"
     gene            3497..4279
                     /locus_tag="VU722_001747"
     CDS             3497..4279
                     /locus_tag="VU722_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU1772672.1"
                     /translation="MALEAFRQDDFDLALKRTIRSLTRGKTVSTSPQAILLGGQSGAG
                     KTTIHRIKQKEFQGNIIIIDGDSYRSLHPNYLVLQEEYGKDSVDYTKFFAGKMVEHLV
                     DELSKDGYHLLIEGTLRTTEVPRKTAQLLKSRDYQVSLALIATKPELSYLSTLIRYEE
                     VYAENPSQARATSKEHHDGIVEHLVDNLRELETDKLFDQIQIYQRDKRCVYDSDTDDG
                     SVADVLQDCLFGKWSKVEEEMIKEAKEYLKRLSKSNNENILV"
     gene            4476..5039
                     /locus_tag="VU722_001748"
     CDS             4476..5039
                     /locus_tag="VU722_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772673.1"
                     /translation="MTESQNIGNFSNNNVQNMYVTNIEQRTLIPTVIFQLLKYVEGFH
                     SQNDEKFLLEQPAELKEKLQFNNSRRYIRLFKEGLSNYISLEKVLKDEFTDSQRVVEN
                     IKNIFMDHTPIDAEGNPIVGNGDECLKKMHDDIKERIARDPNFLSSQIDDLELDKFII
                     ALLQYGVIECQILLNPNNYMECNDVIT"
     gene            5026..5259
                     /locus_tag="VU722_001749"
     CDS             5026..5259
                     /locus_tag="VU722_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772674.1"
                     /translation="MLLLDKNAEPKKTIFYLSAIVHGLILKRIVNIENLYIELQKEIE
                     DELNYDFFILALDFLFLLDKIRVNNEGDIESVH"
     gene            5249..6967
                     /locus_tag="VU722_001750"
     CDS             5249..6967
                     /locus_tag="VU722_001750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEU1772675.1"
                     /translation="MFIKSLSIISKNTDVVLRKIEFKNGINFIVDSEKSYKHNKVGKT
                     TCLKLLDLSLGAKSKDAIFKDYETQSVNEQLRLFIENQKIYTDMVLIDDFNHPSKEVS
                     IKTELFNRGKRYINGEQTSYDEVNKYLNELLFENRSQKPSFRSAIKSFVRILMTKDNT
                     QFLKVLDNFSNISEYRAVYNYLFDISDLENDLEFGKLKQELKNIKSKENNYKKVNTVD
                     DVVKIKQINVAIEKEIDRLEKEINDLVDKKAFEKNRIHINDIRKKYEEISRQLSKIDF
                     DILQLQKYIKEAEEKSQRIVNQELANDFFQEISELLPSITKTFMDLVEFNSQLSRNKL
                     SYFNDRMQELIMEKEDKENLLTKLTEENSEFISLVEENKVDLYYDKLNQLDELKIKKV
                     KNESTITSLGNIEEQKNTLEKRLSKLEMIVKNNEAEYQKKMDIFNSYFKSVADRINKE
                     QPVLLYNPKTDEFPVSIGQLSEGTSTGTRKSLIAAYDIAYQLFAREINKATPKFIVHD
                     VLESIEGDDIRALVDEVESNQIQYISAILKEKLVSSGMSTEKQNEIIVLQLSMKDRLF
                     ERGNNC"
     gene            7301..7663
                     /locus_tag="VU722_001751"
     CDS             7301..7663
                     /locus_tag="VU722_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772676.1"
                     /translation="MRQDIKLIRKQFRITRQEDNQIKEMMREQQLESFSEFLRQNLLK
                     KESHEDVLIRWFTLWQSQKIEQISRDILQVTTLAEQSHQVTAEHLRIILTCVQELIAE
                     VNQASPLSQDFRDKYMGG"
     gene            7666..8031
                     /gene="mobC"
                     /locus_tag="VU722_001752"
     CDS             7666..8031
                     /gene="mobC"
                     /locus_tag="VU722_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEU1772677.1"
                     /translation="MENRYRTNLKKVFLTDQELAVLHDRIGQSRCKNFSAYARKVLLN
                     PNMTFLTIDTSNYEDLVFELRRIGNNINQIARTVNQNHILTPSDRELLVQGICQLIKE
                     VEKDFNIKCQQLKEFYGSH"
     gene            8018..9904
                     /locus_tag="VU722_001753"
     CDS             8018..9904
                     /locus_tag="VU722_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU1772678.1"
                     /translation="MVVTKHFAVHSTKYRKSLIKYILNPEKTEQLKLISDFGMRNYLV
                     FPSYEEMVEMYEANLTNNDRLYDSRNDRQQIKQTKIHAHHLIQSFSPEDKLTPEEINR
                     IGYETIKELTGGNFRFIVTTHTDRNHVHNHILINSVDLNSDKKLKWDYVQERNLRMIS
                     DRLAKEAGATIIQPNRYSHEKFETYRKTNHKFELKQRLYFLLEHSNNFEEFLAKAPAI
                     NVEMDFSHKHARFLMTDREMKQVIRGKQLDKRQPYTEDYFREQFATRAIEQRLDFILP
                     RARDLSHLLEMAEQLNLTISPKKKHVTFTLTEKGRTISIENKKISTKHLYDVQFFEDY
                     FDQRESLTDPDLTNLVSDFEIYQEEQDKDKLPSEELLAAYKEFKEKRDQIQEFEVVLA
                     DHQIDKVVKDGLFIKMNYGVKKDGLVFIPNRNLDIHENEQGKSHHVFIRETAQFFIYN
                     KDSVDLNRYMRGRELICQLTHDSKHIPKRRRPTIASLKEKISEVNLLIELDINNQSYQ
                     EVKDELIKDIAQLDLTITNLQDKVAHLNKVAEILLNLNNSDPENRRLARYDYVKMNLT
                     AAINFEQVEQEISRSQQSLKDLIDKYEFKVRRLEKFVKNISSIYDYPFGGKTYTNNYQ
                     PDFE"
     gene            10311..10571
                     /locus_tag="VU722_001754"
     CDS             10311..10571
                     /locus_tag="VU722_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEU1772679.1"
                     /translation="MDNNFMSFPDRIGTNSSKWRIFETNPNMVSSSLADMDFEIPEFI
                     RSVFIDYMALDFMGYSYQSEKALEAILNWEKKNMGTILIKKN"
     gene            10526..10903
                     /locus_tag="VU722_001755"
     CDS             10526..10903
                     /locus_tag="VU722_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU1772680.1"
                     /translation="MGKKEHGYYFDKEKLILLDSVMTGVANAIQAFTNLGDAVLINDP
                     VYPSFKQIIENNGRKPVFSELEIKDGVYRFNFEKFEDCIITNKVKVFVLCNPHNPLGR
                     AWEIAELNKIGNICLKYNPDFIT"
     gene            11033..11302
                     /locus_tag="VU722_001756"
     CDS             11033..11302
                     /locus_tag="VU722_001756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772681.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVRQRILKKYGWMVLDNL
                     IEDKVLETAISEGFFYVKEYNRGKKIVIRCLLCFTKKISIITVVK"
     gene            11260..12243
                     /locus_tag="VU722_001757"
                     /pseudo
     CDS             11260..12243
                     /locus_tag="VU722_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12233..13345)
                     /locus_tag="VU722_001758"
                     /pseudo
     CDS             complement(12233..13345)
                     /locus_tag="VU722_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            13607..13804
                     /locus_tag="VU722_001759"
     CDS             13607..13804
                     /locus_tag="VU722_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772682.1"
                     /translation="MYIRVKNLREDSDYNQSQIAQYLNCSQSTYSRIESGIQDIPTQF
                     LKKLAKLYGVTTDFLLEMDKE"
     gene            14075..14215
                     /locus_tag="VU722_001760"
     CDS             14075..14215
                     /locus_tag="VU722_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772683.1"
                     /translation="MEKTQTGADLPQVVIEGYKVTVRVTDKPLSLTDVLDDLLGRQLE
                     KI"
     gene            14315..15883
                     /locus_tag="VU722_001761"
     CDS             14315..15883
                     /locus_tag="VU722_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1772684.1"
                     /translation="MTRACTYLRLSRDDGDNVESNSIINQRSLLRDYARRHDFTILEE
                     FVDDGISGLTFNRPDFNRMMVMVNNKTIDTIIVKDLSRFGRDYIETGKYLQRIFPAMG
                     IRFISVNDHYDSLTADTNETHLVMPIKSLINDSYCRDISTKVRSTQKAKRQKGEFIGA
                     FAPYGYRKDHNQRNHLVVDEAVRSTIETIFALKLEGYSSNAIANFLNQAGVETPLQRK
                     RACQERIKGFYGYRHKWDTKMVNRILTNRVYTGTLEQGKQTKLNYKSQKSVAVNPEDW
                     VRVEDTHEAIISTSTFSIANNLLLRDVKHGKNTPDLFAGLLFCGDCQAQLLQRKLRYK
                     DKETVQYICSTYNNGQGCSRHAIKEDVLTDLVSTIVHQHLDWKSYLVKSIPDYLDQEH
                     FLEVDFTSLISERQKYEQLLQSLYLDLDDGLINETEYQEFQRSYRQKLKQIEDTIVQK
                     KELAQTLYDKLQDKETWLEQLSTIQHEQELNRLTLVTLLDRIIVHEQQALTLMFHDVA
                     ELSLLQQFSNMEVV"
     gene            15883..17499
                     /locus_tag="VU722_001762"
     CDS             15883..17499
                     /locus_tag="VU722_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1772685.1"
                     /translation="MARTKNRSRVETVEKIPLQTYRTGIYIRLSKERTESWRHKSQSL
                     KTQESLARTFAQEKGLTVTKCYIDYEYSGTKFNRPAYQDMMEDIKRGVINCILIRDLS
                     RLGRNYIEIGRLIDKVFPFMGVRFISINDNLDTLNGLEDKKSFEVEIKNLVNDLYSKD
                     ISKKVMSYNIHQASQGYYIGTSAPYGYRIDRQEAGARLVIDNQVKPILEFIFQQAIEG
                     VSISQITTELNHRGIAVPQSYRGTGQLYRSEQDIKRWHAGNLLRLIKMPVYRGVLIQR
                     TRNKSLSEEDYIHFENAQEAYVSKDNYEKILFYLDSRKSVKKTSIVRTPNRYRGLVYA
                     KTKSTQMVRRCRHFSNNKSDYDYYYFTDYIYDSETTERKTVYISENALDKIIVELIQS
                     EMKRLGTVETLLPRLETKKDDCLKTYHKQITCHQWTITQLQAELSDLYASFSLNRSER
                     EVYLSQKNEIIAKIETISQEIALCETSIKQIEEEHSKQVNWVRHLAKSQNQVVLTAEL
                     LNALIERIEVDVDKTVTVTFSCQIGGGEHD"
     gene            17492..18931
                     /locus_tag="VU722_001763"
     CDS             17492..18931
                     /locus_tag="VU722_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1772686.1"
                     /translation="MTKIALYLRLSVDEADTDESNSITNQRYLLNNYLDQTPEFKNWE
                     RLEFVDDGFSGTSLKRPAFQRMMADVKAGTIRHIIVKDLSRFMRDYLELGNYLENIFP
                     FLGVRFIALNDHYDSLVSEHNGLDIDVPFRNLLNDFYAKDVSEKVKSAMNSMKRSGKN
                     MSWLPPFGYIKDPNDRFKIIIDEEVAPIVRRIFRLCIEGMGTQKIAMLLNSEQTITPA
                     ERKMQVSQARYTKSIIITAEQKRNVWTRSGILQILKNEAYKGTYLFNTRTTVNGKQIR
                     RPESEWERLDNNHEAIVSSEDFDKAQQSLTSRISGTKSQVCNQPEEVLLRGLVICEHC
                     GHRLLRYSHNNNNNYFYCCYCRSQGQNMKSCRIDRIEEAIEKELKSRLPMNSPKLSKT
                     NLIREVERLKTQKVSHFQDYKEGLMTRETYMEKRQNLDNSIMEIEEQLKVVGRENIAF
                     DKKLTREVVDTHIERIVVNGQGSFTVVYK"
BASE COUNT         6548 a         3222 c         3802 g         5450 t
ORIGIN      
        1 taaaataggc tccataatat ctatagtgga tttacccact acaaatatta tagagccgct
       61 tttttgtggt cgagaactat tttgtcctag gctcttttct tttttgtgat aacttttcca
      121 agtcaatctt gttatgatgg tgctatctta cggaaaaagg agatggcact attgatgtta
      181 aataaaatga aagtgagttt tttgcttggt ttaggtggtc tagcagtcat gagctttgtg
      241 gtgatgatgg gctacactat tggttctcag tctgtgaccc atcacatgca gaaacaaatc
      301 cagactgaag ctcataaact attgacccaa gagaaagaaa aggagaaagc aagtgtcctc
      361 tcagatgagt tggtcaaaga atttctcacc caatactaca ctaagggaaa gctgggggag
      421 aacaacaacc gtattaagct ctatatgacc gactctgctt ataaggaaga agtagctcgt
      481 caagaagatt ccatcaatca ggtctataag gactatatgt tggattatcg ctttgagact
      541 gctcaaatct atgtcaatac agaagcaaat gaagctcttg cggaagtatc ctatcaggtt
      601 gtttatgtgt cagatgttag tgataaggct cagaaaagta cacaaacaga aacgaaatct
      661 cttaaactat cttataccaa aatgtcagat aaatttcttg tcaagcaggt aactgtttgg
      721 aacggaaagc tagagaactt aaaagaagtt tctgatggag ctgattcaag cattccagat
      781 attcaaggca ctactacaag tgagaccaac tagcaggagt tacccttctg cttttttgat
      841 agggagatga gatgacaaga attgaagcag tgaaacaaaa agcaatctta gaggttgcag
      901 aaagtctagg ttattctttt aaacgactat cagggcaagt ctatgaacat ccagaacacg
      961 attcctttag gatttttgcg gataccaata cttttaaatg gttttcacgt gacatacagg
     1021 gagacgtgat tgattttgtt cagttaataa caggagtgac ttttaaagaa gctctgtctt
     1081 accttgaaac aggggacttt gaacagacta agatggttga agagacttac caaccctttc
     1141 gctattatct aagggaagaa ccattttacc aagcacggat atacttgaat gacattcgtg
     1201 gtttaagcga tgacactatc aatgcttttg gcagacaagg gctgttagcc caagctcatt
     1261 atcagacaaa gatctttcaa gaatcagttc ttgtttttaa gagttacagt catcatgggc
     1321 aactagaggg ggcaagtttg caggggcttg ttaaaaataa tgagagacat gatcgagatt
     1381 atctcaagaa aatcatgaaa ggttctcatg gttatgttgg gatgagtttt gatataggaa
     1441 agcctgaacg ccttatcttt tgtgaatcag tgattgacat gatgagctat tatcaactcc
     1501 atcagaatca gttatcagat gtgcgtttag tttctatgga aggtctaaaa ctctctgtga
     1561 ttgcgtatca gtccttacga ttagtagctg aggaacaagg caaacttgag tttttagata
     1621 ctgtaaaacc aagtcgatta acgcattacc ttcatgccat acaagagaca accacttttt
     1681 ttcagactca cccaagtctg ataaccttag ctattgataa tgatggagca gggcgagact
     1741 tttgtcagaa attatctgag aaaagccttc ccattgaaac agacttacca ccattacagg
     1801 aactggaaac taaagctgat tggaatgatg tcgtgaaaag tcagaaagac ctttctctaa
     1861 aggatatgat ccaatcggcc aagttacaag ttatccgaag caatcctcct cctagaaaaa
     1921 ataccgcttt agagttgtga taacaaaatc aagtttctta gcttaatcta gaaagtgata
     1981 aggaggacac cctatgagtg tgattgaacg cctggctgaa agagtagcta ggcaagagga
     2041 aaaagttgcg aaagaaacgg aaaagctagg aacctatcgt gagcagttac aggcagctat
     2101 gtatagcata tttgtcaagc gtcagcagtc gagtcatctt acttttgatg aggctttaaa
     2161 ccaggcgttt ggtaagcagg aaaatcattc acaggtaatc gaaaatagaa atgaggaaac
     2221 agaatgacaa aagattggac ttttgaccaa tccctagatg ataacacacc aacgtcttcc
     2281 acagaagaac gtgcgaagat tgcagcccta tttcataagg aagagaaaga agaaactgga
     2341 gaagttaatt atgtggcagc ctttgaaatg gagcaacaaa aagctaagga gaaatcagtt
     2401 tcaaaaccaa aagttcaaga gcaatccaca ccaaaagaag tgccctcttc aaccattacc
     2461 agtgactaca agcaacatct agccaatgtg atggctcaaa acaatgagga cattcttcaa
     2521 agtcaaaaga aaatcgaaga gctgaaccag ttgattgatg acaaaaataa gcagaataag
     2581 aaattacaag ccatttcaga agctattgat gacttgtaag tacgagcagt ccttatgtgg
     2641 gctgcttttt acgaggggga acagatgagg ttattcaaaa aacaaacgca caatcaagat
     2701 agttttaagc gactcattca tcgcttatca ggaatgtctg agactgactt acacaaagtt
     2761 aaccaattat tagatgtcgt ttttgatgct acaagtcaaa ctatccatga agaaacaatg
     2821 actcctaaag atatgccaaa ggagcctata ttagatgaga ctattactga agctaagaat
     2881 aaactgaata ctgagcaact ggaaaaacgg atagaacagt ttagacaggc gaagaaaccg
     2941 aaaagcggat aatgcaccaa aaatggtgcg ttatccattt tttgtgctat aatgaaagta
     3001 acgaatagga ggtcttatct atgattggag agaatatcaa atcattacgc agaacacacg
     3061 atttgacaca accagagttt gccaaaattg ttggtatttc aagaaatagc ttgagccgtt
     3121 acgaaaatgg gacaagctct gtttcgacag aactcattga tcgaatttgc caaaaattca
     3181 acgtgtcata tgtcgatatt gtaggagaag aaaagatgtt aacaccagta gaagattatc
     3241 aattgacgct gaaaatagaa gtcatcaaag agcgtggagc agcggtttta tctcaactgt
     3301 atcgctatca agatagtcaa gggattgctt ttgatgatga gactaatcct tggattttga
     3361 tgagtgatga cttgtctgac cttatcaata ccaagattta tctggtcgat acctttgatg
     3421 aggtagaacg ctacaatggt tatttggatg gcattgagcg tatgttggaa cttgctcgtc
     3481 atcaggtggt ggcttaatgg cattagaagc atttcgtcaa gatgactttg acctagccct
     3541 gaaacgcacc atccgttctt taacccgagg caagacggtt tcgactagcc cacaagctat
     3601 tttacttggg ggacaaagcg gagcaggtaa gacgaccata caccggatta aacaaaagga
     3661 atttcaaggc aatatcatca ttattgatgg cgatagctac cgctctttac acccgaatta
     3721 tcttgtctta caagaagaat atggtaaaga tagtgtggat tacaccaaat tctttgcagg
     3781 aaaaatggta gagcacctcg ttgatgaact cagcaaagac ggttatcatt tgttaattga
     3841 aggaaccttg agaacgacag aggttccaag aaaaacagct cagctattga aatcaagaga
     3901 ttatcaagta tcactcgcat tgattgcgac taagcctgaa ttgtcctatc tcagcacctt
     3961 aattcgctac gaggaagtct atgccgagaa tccaagccaa gctagagcaa cttctaaaga
     4021 gcatcacgat ggtattgtag aacatttggt tgataatcta agagagttag aaactgataa
     4081 actctttgat cagattcaaa tttatcaacg agacaaacgc tgtgtctatg attctgatac
     4141 agacgatggt tcagttgctg atgtgttgca agattgtctc ttcggaaaat ggagtaaggt
     4201 tgaggaggag atgattaagg aagctaaaga atatttaaaa cgattgagta aaagtaataa
     4261 tgaaaatatc ttagtatgaa atagaggtag aaaatagtgg aaacagtaaa cacaatttta
     4321 ggaatagtag gatctatatt tggcataatt gctacagcaa tttctttaaa aaaccagaac
     4381 gatattaaaa aaattataaa gaattccaat aatagccaaa atataggtaa caatagcagt
     4441 aataatgtac agaatattgg tgatgggaga taaaaatgac tgaatcccaa aatatcggaa
     4501 attttagtaa taataatgtt caaaatatgt atgtaacaaa tattgagcag cgtacattga
     4561 tcccaactgt tatttttcaa cttttaaaat atgttgaagg atttcactct caaaacgatg
     4621 aaaagttttt acttgaacaa ccagctgaat taaaggaaaa actacaattt aataattcta
     4681 ggagatatat tagattattt aaagagggtc tcagtaacta tatttcacta gaaaaggtat
     4741 taaaagatga attcacagat agtcaaagag tagttgaaaa tataaagaat atttttatgg
     4801 atcatactcc tatagatgca gaaggaaatc cgatagtagg taatggtgat gaatgtttga
     4861 aaaagatgca tgatgacata aaagaaagaa tcgcgagaga tcctaatttt ttatctagtc
     4921 aaattgatga cctagaattg gataaattta ttattgcact tcttcaatat ggagttatag
     4981 agtgtcaaat attattgaat ccaaataatt atatggagtg taatgatgtt attacttgat
     5041 aaaaatgctg agcctaaaaa gactattttt tatctctcag ctattgtaca tggcttgatt
     5101 ttaaagagga tagtcaatat agaaaatctt tatatagagc ttcaaaaaga aattgaagat
     5161 gaactaaatt atgatttttt tatattagca ctagattttc tttttctatt agataaaata
     5221 agagttaata atgaaggaga tattgagagt gttcattaaa agtttgagta ttatcagtaa
     5281 aaatactgat gttgtattga gaaaaataga atttaaaaat ggaattaatt tcatagtaga
     5341 ttcggagaag tcttataagc ataataaagt tggaaaaaca acatgcttaa aattactgga
     5401 tttaagttta ggggcaaaaa gcaaagatgc catttttaaa gattatgaaa cacagagtgt
     5461 taatgaacaa ttaagattgt tcattgaaaa tcaaaaaatc tatactgata tggtgttaat
     5521 agatgatttc aaccatcctt ctaaagaagt ttctataaag acagaattgt ttaacagagg
     5581 taaacggtat attaatggag agcaaacttc atatgatgaa gttaacaaat atttaaatga
     5641 attattgttt gaaaaccgct ctcaaaagcc aagttttaga agtgcgataa agtcatttgt
     5701 acggatttta atgactaagg ataatactca atttttaaaa gtattagata atttttcaaa
     5761 tatttcggaa tatcgcgctg tatataatta tttgttcgat atttcagatc ttgaaaatga
     5821 tttagagttt ggtaaattaa aacaggaatt aaaaaatata aaaagtaagg aaaataatta
     5881 taaaaaagta aatactgtag atgatgtagt aaaaataaaa caaatcaatg ttgcaattga
     5941 gaaagaaatt gaccggttag aaaaagaaat aaatgattta gtagataaaa aagcatttga
     6001 gaaaaataga attcatatca acgatattag aaaaaaatac gaggagataa gtcgacaatt
     6061 aagtaaaatt gattttgaca ttttacagtt acaaaaatat atcaaagagg ctgaggagaa
     6121 atcccaaaga atagtaaatc aagaactggc aaatgacttt tttcaagaga tttccgaatt
     6181 gttacctagt attactaaaa cttttatgga tttagttgaa tttaattccc aattgagtag
     6241 aaataaattg tcttatttta atgatagaat gcaagaattg ataatggaga aggaagataa
     6301 agagaattta ttgacgaaat tgaccgaaga aaattcagaa tttatatctt tagttgaaga
     6361 aaacaaagta gatttatatt atgataagtt aaatcaacta gatgagttaa aaataaaaaa
     6421 agtaaaaaat gaatcaacaa ttactagttt aggtaacatt gaggagcaaa aaaatacttt
     6481 agaaaaaaga ctttctaaac tagagatgat tgttaaaaat aatgaagcag aatatcagaa
     6541 aaaaatggat atttttaata gttattttaa gagcgttgca gatcgaataa ataaagaaca
     6601 acctgtcttg ctttataatc ccaagacaga tgaatttcca gtttcaattg gccaactatc
     6661 tgaaggtaca agtacaggga ctagaaagtc ccttatcgct gcatacgata ttgcttatca
     6721 actttttgct agagaaatta ataaagcaac tcctaaattt attgttcatg atgttcttga
     6781 gagtattgaa ggtgatgata ttagggcgtt agttgacgaa gtggaaagca atcaaataca
     6841 atatatttca gcaatcttaa aagaaaagtt agtatcctct ggtatgtcaa cagagaaaca
     6901 aaatgagata attgttctac aactttctat gaaagataga ttgtttgaaa gaggaaataa
     6961 ttgttagata aaatataagt cttgaatttt aaaaggaagt tcaagacttt tttgtgataa
     7021 cttttccaaa tcatccttgt tatcctaatg tcattcctaa gaaaatcaaa tcttgatttt
     7081 tcactggggg tttgggggcg aagccaccat agtttcttat cgtcggctga caaacctgta
     7141 aggttttggt tggctgacga ttagattttg ggttattgtg gacacaataa ctgagctcgc
     7201 aaaagccgaa aaagaacctt ttgaggcttt taggaagtgt actgacagtg tgaggctgcc
     7261 ttacattgtc aggcaagtaa ttttttgaaa ggataaaacc atgagacaag atattaagtt
     7321 aatcagaaaa caattcagga taacaagaca ggaggataat cagataaaag aaatgatgag
     7381 agaacaacaa ttggagagtt tctctgaatt ccttcgccaa aatttattga aaaaagagtc
     7441 tcacgaagac gttttgattc gctggtttac tctctggcaa tctcaaaaga ttgaacaaat
     7501 cagtcgagat attttacagg tgactacctt ggctgaacaa agccaccaag ttacggcaga
     7561 gcacctacgg attatcttga cctgcgtaca ggagctaata gcagaggtta accaggctag
     7621 tccacttagt caagactttc gggacaagta catgggaggt tagggatgga aaatcgttac
     7681 cgcaccaatc ttaaaaaagt ttttctgaca gaccaggaac ttgcggtctt gcacgaccgt
     7741 atcggacaga gtcgctgtaa aaatttctct gcttatgcca gaaaagtttt gcttaatcct
     7801 aacatgacct tcctaaccat tgacaccagc aactatgaag acctggtttt tgaattgaga
     7861 cgaattggaa ataacatcaa tcaaattgca cgaacggtca atcagaacca catcttaaca
     7921 ccaagtgacc gtgagttgtt ggtacagggc atttgccaac tcatcaagga agttgagaag
     7981 gacttcaaca taaagtgcca gcagctgaag gagttttatg gtagtcacta agcattttgc
     8041 ggttcacagc accaagtacc gcaagagcct catcaagtat attctcaatc ctgaaaagac
     8101 ggagcagttg aagttgattt ctgattttgg catgaggaac tatttggttt ttcctagtta
     8161 tgaggagatg gtggagatgt atgaggccaa cctcactaac aatgataggc tctacgattc
     8221 tagaaacgac cgccagcaaa tcaagcagac caaaatccat gcccaccact tgattcaatc
     8281 tttttctcct gaagacaagc tgacaccaga ggaaatcaac cgcattggct acgagaccat
     8341 caaggaactg acaggtggaa actttcgttt tatcgtgacg acccacactg atagaaacca
     8401 tgtgcataat catatcctga taaactctgt tgatcttaac tctgacaaga agctcaaatg
     8461 ggattacgtt caagagagaa accttcgcat gatttctgac cgcttggcca aggaagcagg
     8521 ggcaacgatt atccagccta accgttattc gcacgagaag tttgagactt accgcaagac
     8581 caatcataaa tttgaactca agcaaaggct ttattttctc ctggaacaca gcaacaactt
     8641 tgaggaattt ttggccaagg ctcctgctat aaacgtggag atggattttt cccacaagca
     8701 cgcccgtttt ctcatgaccg accgagagat gaaacaggtt attcgcggta agcaattgga
     8761 caagcgacag ccctacaccg aggactattt cagagagcag tttgcgacac gagccattga
     8821 gcagcgattg gattttattt tgcctagagc ccgtgacctc tctcatcttt tggaaatggc
     8881 agagcagtta aacctgacaa tctctcctaa gaaaaagcat gtgactttta ctttgaccga
     8941 gaaaggtcga accatttcca ttgaaaacaa aaagattagc actaaacact tgtacgatgt
     9001 tcagttcttt gaggattatt ttgatcaaag agaatcccta acagatcctg acttaactaa
     9061 cctggtatca gactttgaga tttatcaaga ggaacaggac aaggacaaac ttccaagtga
     9121 ggaactccta gcagcctaca aggagttcaa agagaaacgt gaccagattc aggagtttga
     9181 agttgttcta gctgaccatc agattgataa ggtggtcaag gacggtcttt ttattaagat
     9241 gaattacggt gtcaaaaaag acggcttggt attcatacca aaccgtaatc tagatattca
     9301 cgagaatgag cagggtaagt cccaccatgt ctttatacga gagaccgccc agtttttcat
     9361 ttataacaaa gacagtgtag acctcaatcg ttacatgaga gggcgtgaac taatttgtca
     9421 actcactcac gacagcaaac atatccctaa acgtaggcga ccaactattg ctagcctcaa
     9481 agagaaaatc tcagaggtta atcttcttat tgagttagac atcaacaacc aatcctatca
     9541 ggaagtcaaa gacgagttaa tcaaagacat cgcccagctg gatttgacca ttacaaatct
     9601 gcaggataag gttgctcatc ttaataaggt cgcagaaatc ctgcttaatc tcaataactc
     9661 cgatccagaa aatcgccgac tggccagata tgattacgtc aagatgaacc tgactgcggc
     9721 tataaatttt gaacaagttg aacaagagat ttctcgctca caacaatctt taaaagactt
     9781 gatagataaa tatgaattta aagttaggag actggaaaaa tttgttaaaa atattagtag
     9841 tatttacgac tacccctttg gaggtaaaac atatacaaat aactatcaac ctgattttga
     9901 ataaacattt gtcttttaga tgatttgtat acgatatttt ataaatgatt accacttttt
     9961 atttttcaag aatcaaaata accgtattaa tgtatatttt ttatatagta cagtattaaa
    10021 taggttatct gaagtgacac ccaaaaattg ttatataaag aaaaaggtac tagatatgct
    10081 ttttcatatt ttaacttaaa taaaatggca aactaaaatt gtaaaaataa tttagcgaat
    10141 taaagaatat tgaactataa attaaatcag tgagatgtgt ttactaaatc aaaaaaatta
    10201 aactaaggta tttcatattt ttagttaatc tggtagactt tagtaagttg tataatattt
    10261 aagtcaattt ttagaggagg ctttaaaatg taagagagga agagagaata atggataata
    10321 attttatgag ctttccagat aggattggaa ctaattcaag taagtggagg atttttgaaa
    10381 caaatcctaa tatggtttca tcttctttag cagatatgga ttttgaaatt cctgagttca
    10441 ttagaagtgt ttttattgat tatatggcat tagattttat gggctatagt tatcaatctg
    10501 aaaaggcttt agaggctatt ttaaattggg aaaaaaagaa catgggtact attttgataa
    10561 agaaaaacta attttgctgg atagtgttat gacaggagta gctaatgcaa ttcaggcatt
    10621 cacaaatttg ggagatgctg ttttaataaa tgatccagta tacccttctt ttaagcaaat
    10681 aattgaaaat aatggcagaa aacctgtttt tagcgagtta gaaattaagg atggggtata
    10741 tcgatttaat tttgaaaagt ttgaggactg tattataaca aacaaagtta aagtttttgt
    10801 tctatgcaac cctcataatc ccttaggtag ggcttgggaa attgctgagt taaataaaat
    10861 tggaaacatt tgtttaaagt ataatcccga ctttatcact taatttttac caagccctac
    10921 ttaacccctt ggtacatctg gatttcccaa ctattcccca acttttgttt gttatatatg
    10981 attatgtatg attatgtatg attgtgtatg attgtgtatg atataataga gtatggcatt
    11041 tattaaaaca acaaccaaca aagaaggacg tactcatgtc tatcttgtgg aaggatatcg
    11101 caaagatgga aaagtcagac agcgtatctt gaaaaaatat ggttggatgg tcttggataa
    11161 cctgattgaa gacaaagtcc tagaaacagc tatttctgag ggcttttttt atgtcaagga
    11221 gtataataga ggtaagaaga ttgtaataag gtgtttgcta tgtttcacaa agaaaatctc
    11281 gattataacc gtcgtcaagt aggcttctat acgcttgaag agatagttcc aaaggaccac
    11341 tttctgcgtt agttggagga aactgtcgac ttttctgtca tctatgatct agtggagaat
    11401 agttattcct cagacaaggg acgtcctagc cttgaccctg ttatgctggt caaaattcct
    11461 ctgattcagt gcttctatgg cattcgctcc aggcgtcaga ccatcaagga cattgagatt
    11521 aatgtcgctt atcgttggtt tctgggcttg actctggacg ataaagtgcc tcattttacc
    11581 acatacggta agaactacag tcgtcgtttt gctgaaacag aattgatcac gcgtatcttc
    11641 gagcatgtcc tccatctctg tttgactgct ggcttagtgg atacagatga gattttcatc
    11701 gacggaacgc aaatcaaagc agctgccaac aaccataaaa atagacgaca agaggttgag
    11761 gctcaagcta aatggatgag tgaacaactc gacaaagaaa tagcacaaga tcggataaca
    11821 catggcaaaa agcccctaaa gcccgccata aaaggcgagg ctaagaccaa aaagatgtcc
    11881 atgacagcca agctttccct gcccttttcg caaagctagc accgtttcac cccaactata
    11941 tcatcgctga ctctggttat aaaaatccca gtattgccaa atgtctactg aaccagcata
    12001 tcacgcctgt cttttcctac accagacctc gtggcaagaa gggcatgtta cgaccgaatg
    12061 atttcattta tgacgagcat tataacgtct acctctgtcc tgaaaaccaa gtcttacact
    12121 acagcactac caaccgttct gactatcgag aataagagta accccaagac ttgtgccact
    12181 tgtctactcc taaaccgctg tacccaaagt aagaccaagc agaagctggt caccagatat
    12241 gtctcgttac tactttttga aaattcttgc tttgggtaca aatggataat aaaggacagg
    12301 aaacacatac tttgggatta ctcttatact cacggtagcc ttctcgagtg gtagtgagat
    12361 agcttaatac ttgattcctg gacagacata atggtcataa cttgcatcat aaacaaaatt
    12421 actaggcctt aagttcccct ttactccctt tggacgagta taagggaaaa caggaatgat
    12481 attacgttct aacaaataat gggcaatagc ttgggtcttg taacctgaat ctgcaataat
    12541 atagtggggg gagaatggct ctaactttga aaatagggca gggaaagctt gactatcatg
    12601 aacatttcct gcttcaaccg tataagctaa ggaccatcca tgcttatcac aagcaacttg
    12661 ggcagaatag gcaaatactt ccttgtgttc gcccttgtga aacaaaccac actcgggatc
    12721 tgtcgttgag attttctttt ccttagcttc actttctttt gcgggcttta aggacttttt
    12781 tcgtgttttt tcttatctaa atcaatctca actgccaatt gttcactcat aaatctagct
    12841 tgttggtcta ccatttcctt acgggacttg tgactattag ctgccacttt gatatgggta
    12901 ccatccacaa atatttcaga agaatcaatt aaggcaacat acaaagcttg gttgagaact
    12961 tgggaaaaat ctcagaaatg agttctttat cttgaaaacg acggctgtaa ttctttccat
    13021 aggcagtaaa atgagggacc ttatcatcta aagttagtcc aagaaaccaa cgataggcca
    13081 cgtttacttc aatctctttc atggtttggc gcatggaacg aatgccataa aaacatttga
    13141 tttaaggaat tttgactaat atgacgggat caagactagg acgaccatta tctggactat
    13201 aggtatcttc taccaagtca tagataaagt caaaatcaac cttggaatct acttgtcgaa
    13261 gaaagtgatc ttctgggacc aattcgtcta ttgtatagaa accatattac ttacgattat
    13321 aatcaggttt ttctttgtga aacataagga acacctcaca actcttctta cctctattat
    13381 acgactttac acaaagaaaa gcccttggaa gcttgacttc caatgactgt atcttcggtc
    13441 tgaaacttct agagtcaaca aagactttgg aagttttcaa tataatctgt tattggacgg
    13501 ttacgtagtt tctgattatt ctttaaaata aattatttat gcaagttttg catagaaccc
    13561 catctttatt tttagaatta ctaaaatagt aattggaagg ggttctatgt atattcgggt
    13621 aaaaaattta agagaagaca gtgactataa tcagagtcaa attgcacaat atctaaattg
    13681 ttctcaatct acttattcca gaattgagag tggtattcag gatattccta ctcagttttt
    13741 aaaaaaatta gcaaagttat atggagtaac tacggatttt ttactagaga tggataagga
    13801 ataataccct tcttttgttc cttgacaact gaatagacca aggtgggact ttaatcattt
    13861 gtggagcaag ttagttagat acgctgtgat atgagcgaga attatcagct ataaaataga
    13921 gtggtactct atctgccatg atacaagtga agataatgat acttctaacc gtttaggctg
    13981 ccagcgagaa aggacagcgg gtgtaagccc catgtagaac ttaaccagtt ctacccattg
    14041 aggtcaacat tttgacgtaa aggaaataac atttatggaa aaaacacaaa caggtgcgga
    14101 tttaccgcaa gtcgtgattg agggctataa ggtgacggta cgagttaccg ataaaccatt
    14161 aagcctaaca gatgttttag atgatttact gggacggcag ctggaaaaaa tttgattttt
    14221 tagcggacaa gtcttgataa atgatgtaaa atagaatagt agaacctcag tccttaatcg
    14281 gtaagcacct aaataactga ttaaggagac aaacatgaca cgagcctgta cttatttacg
    14341 cttatcacga gatgatgggg ataacgtaga gagtaattcc atcatcaacc aacgctcgct
    14401 cttgcgagat tatgctagga ggcatgactt caccatttta gaagaatttg tggatgatgg
    14461 tattagtgga ctgaccttta accgtccaga ctttaaccgt atgatggtaa tggtaaataa
    14521 caagaccatt gataccatta tcgtgaaaga cctgtctcgc tttggtcgag actatattga
    14581 aactggaaaa tacctccagc gaatttttcc tgctatgggg atccgtttta tctcagttaa
    14641 tgaccattat gatagcttga cggctgatac caatgaaact catctggtca tgcccattaa
    14701 aagcctcatt aacgatagct attgtcggga catttcaact aaagtgcgaa gtactcaaaa
    14761 agccaaacgg caaaagggag agtttattgg ggcttttgct ccttatggct atcgtaaaga
    14821 ccataatcaa cgaaaccatt tagtggttga tgaagcagtt cgctccacta tcgaaacaat
    14881 ctttgctctg aaattggaag gatattcttc taatgccatt gcgaattttt tgaatcaagc
    14941 tggggtggaa acacctctac aacgtaagag agcctgtcag gaaaggatta aaggcttcta
    15001 tggttatcgt cataagtggg ataccaaaat ggtcaatcgt atcctgacca atcgtgtcta
    15061 tactggcact ttagaacaag gaaaacagac caaacttaat tataagtctc aaaagtctgt
    15121 ggctgtcaat ccagaagatt gggtacgagt ggaagatacc cacgaagcca ttatctccac
    15181 aagtaccttt tctattgcga ataacctctt actcagagat gtcaaacatg gaaagaatac
    15241 tcctgacctc tttgcaggac tcttgttttg tggcgactgc caggcacaac tcttgcagcg
    15301 gaaacttcgt tacaaggaca aagaaactgt tcagtatatt tgtagcacct acaacaacgg
    15361 tcaaggctgt agtcgtcatg ctattaagga agatgtgcta accgatttag tatcaactat
    15421 cgttcatcag catcttgatt ggaagtctta tctagtaaaa tctattcctg attatcttga
    15481 ccaggaacac tttttagagg ttgattttac ttctttgatt tcggagcgtc aaaagtatga
    15541 gcagttgctt cagtccctgt atctggattt agatgacgga ttaatcaatg aaacagaata
    15601 ccaagagttt cagcgtagct atcgccaaaa gctaaagcaa attgaagaca ctatcgttca
    15661 aaagaaagaa ttggctcaaa ccctctacga taagctccag gataaggaga cttggcttga
    15721 gcagttgagc acgatacaac atgagcaaga gcttaatcgt ctcactctag tgactttact
    15781 ggatcgtatt atcgttcatg aacaacaagc attaaccttg atgtttcacg atgtggcaga
    15841 attgtccctt cttcaacagt tttctaacat ggaggtggtc taatggcacg tactaagaac
    15901 cgctcccgtg tagaaacggt agaaaagata cctcttcaaa cctatcgaac aggtatttat
    15961 attcgattat ccaaagaacg taccgaaagt tggcgacata aatcgcagtc tttaaagacc
    16021 caggaaagtc tagctagaac ctttgcccaa gaaaaaggtt taacagtcac caagtgctat
    16081 attgattatg aatattctgg cacaaaattt aatcgcccag cctatcaaga tatgatggaa
    16141 gacatcaaga gaggtgtcat caattgtatc ttgattcgag acttatcacg cttagggcgt
    16201 aactacattg agattgggcg actgattgat aaggtatttc cctttatggg ggttcggttt
    16261 atttcaatca atgataacct agatactctc aatgggctag aagataagaa atcctttgaa
    16321 gtggaaatta agaatttggt caatgacctt tattctaagg acatttcaaa gaaagttatg
    16381 tcctataata ttcaccaagc tagtcaagga tactatattg gaacatctgc tccgtatggt
    16441 tatcgaattg atcgccaaga agcaggtgcg aggttagtta ttgataacca agtcaagcca
    16501 attttagagt ttatttttca acaggcaatt gaaggtgtat ccatatctca gattactact
    16561 gaattgaatc atagaggaat tgctgtacct cagtcatacc gtgggactgg ccaattgtat
    16621 agaagtgaac aggatatcaa aagatggcat gcaggaaatt tgcttcgtct tatcaaaatg
    16681 cctgtttaca ggggagttct tattcaacga acacggaaca aatcgttatc tgaagaggat
    16741 tatatccatt ttgaaaatgc tcaagaagcc tatgtcagca aagataacta cgaaaaaata
    16801 cttttttatc tagatagtcg taagtccgtt aaaaagacta gtatagtgag aactccaaac
    16861 cgctatagag gtctggttta cgccaaaaca aaatcaactc aaatggttcg cagatgtcgc
    16921 catttctcaa acaataagtc tgattatgat tactattatt ttacggacta tatctatgat
    16981 tcagagacaa ctgagagaaa aaccgtctat atcagtgaaa atgctctgga caagattata
    17041 gtagagttga tccaatcaga aatgaagcgg ttaggaacag ttgagacatt gttgccacgg
    17101 ttagaaacta aaaaagacga ttgcctaaag acgtatcaca agcaaataac ttgtcatcaa
    17161 tggaccatca cacagctaca agctgagcta agtgaccttt atgcgtcttt tagtcttaat
    17221 cgttctgaac gagaagtcta tctctcccaa aagaacgaga taatcgcaaa aattgaaacc
    17281 atttcacaag aaatagcctt atgtgaaacc tcaataaagc agattgagga ggagcacagt
    17341 aagcaggtga attgggttag acatctagcc aagagccaaa atcaagttgt tttaacggca
    17401 gaactcttaa atgctttaat agaacggatt gaggttgatg tagacaaaac agtgacagta
    17461 actttcagct gtcagattgg gggtggcgag catgactaaa atcgctctat atctccgctt
    17521 gtcagttgat gaggctgata cagatgaaag caactcaatt acgaaccaac ggtacttgtt
    17581 aaacaattat ctcgaccaaa cacctgagtt caagaattgg gaacgcttgg aatttgtgga
    17641 cgatggtttt tcaggaacca gtcttaaacg tccagccttt caacgcatga tggccgatgt
    17701 caaggctgga actatccgtc atatcatcgt taaagacttg tcacgattta tgagagacta
    17761 tctggagttg ggaaactact tagagaatat ctttcctttt ctcggagttc gatttatcgc
    17821 tctcaacgac cattatgata gcctggtgtc tgaacataat ggactggata ttgatgtgcc
    17881 ctttagaaac ttactcaatg atttctacgc caaagacgtt tctgaaaaag tcaagagtgc
    17941 aatgaacagt atgaaacgct ctgggaagaa catgagttgg ttaccaccgt ttggttatat
    18001 caaggaccca aatgaccgat ttaagattat cattgatgag gaagtcgctc caattgtgag
    18061 acgaattttt agactttgca ttgagggaat gggaactcaa aaaatagcga tgttacttaa
    18121 tagtgaacag acgattactc cagctgagag gaaaatgcag gttagtcaag caaggtatac
    18181 aaaatcaatt atcattactg ccgaacaaaa gaggaatgta tggacgagaa gtggtattct
    18241 ccaaatactc aaaaatgaag cctataaggg gacatacctg tttaacacta gaacaacggt
    18301 aaatggtaag cagattcggc ggcctgaatc agagtgggaa cgtcttgaca ataatcatga
    18361 ggcaattgta tcaagtgagg actttgacaa agctcaacaa tcacttacct ctcgcattag
    18421 tgggacgaaa agtcaggttt gtaatcagcc agaagaagtt ttattgagag gcttagttat
    18481 ctgtgaacat tgtgggcatc gtctccttcg atatagccac aataacaaca ataattattt
    18541 ttattgttgt tattgtagaa gccaaggcca gaatatgaag tcctgtcgga tagatagaat
    18601 agaagaggct atcgagaaag aattaaagtc tcggttgccg atgaactctc caaagctatc
    18661 aaaaacgaat cttataagag aagttgaacg gctgaaaact caaaaggttt ctcattttca
    18721 agactataaa gagggcttga tgacaagaga aacttacatg gaaaaacgtc agaacttaga
    18781 taattctata atggaaatag aagaacaatt aaaggtagtt ggtagggaaa atatagcatt
    18841 tgacaagaaa ttgaccagag aagtagttga cactcatatc gagaggattg tcgtcaatgg
    18901 ccaaggttct tttacagtcg tctataaata acctaatgag agacttgtgt aatagcaagt
    18961 ctctttcttg aaaagtagct ttgtggtata ataagggtgt tttcagtgta gaaaaatagt
    19021 gt
//
LOCUS       DAVFJR010000041        18946 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVFJR010000041 DAVFJR010000000
VERSION     DAVFJR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.042"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(1..995)
                     /locus_tag="VU722_001764"
                     /pseudo
     CDS             complement(1..995)
                     /locus_tag="VU722_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1242..3921
                     /locus_tag="VU722_001765"
                     /pseudo
     CDS             1242..3921
                     /locus_tag="VU722_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            4220..5059
                     /locus_tag="VU722_001766"
     CDS             4220..5059
                     /locus_tag="VU722_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU1772687.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            5077..6915
                     /locus_tag="VU722_001767"
     CDS             5077..6915
                     /locus_tag="VU722_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU1772688.1"
                     /translation="MSYKDKVQKIFDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQSTLVLLVSSCIALVVVGPIGVIVGQGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALFAGITEPAVYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            6928..8343
                     /locus_tag="VU722_001768"
     CDS             6928..8343
                     /locus_tag="VU722_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU1772689.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            8935..9981
                     /gene="pheS"
                     /locus_tag="VU722_001769"
     CDS             8935..9981
                     /gene="pheS"
                     /locus_tag="VU722_001769"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU1772690.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            9981..10490
                     /locus_tag="VU722_001770"
     CDS             9981..10490
                     /locus_tag="VU722_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772691.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            10567..12972
                     /locus_tag="VU722_001771"
     CDS             10567..12972
                     /locus_tag="VU722_001771"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU1772692.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNIGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLVDVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDCLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(13040..13807)
                     /locus_tag="VU722_001772"
     CDS             complement(13040..13807)
                     /locus_tag="VU722_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU1772693.1"
                     /translation="MLLLSLILLLFGTDKTLSSASNKTKTLKLVTWNVANQIEAQHIE
                     RIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGLSMANYDIFTSPPTNNGIAPV
                     TVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDIIALHTAPPLPGLMEIWKQDLN
                     IIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDALNALPPFERGTWNSQSPKLFN
                     ATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            complement(13833..14042)
                     /locus_tag="VU722_001773"
     CDS             complement(13833..14042)
                     /locus_tag="VU722_001773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772694.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFPIFLQEK"
     gene            14197..14685
                     /locus_tag="VU722_001774"
                     /pseudo
     CDS             14197..14685
                     /locus_tag="VU722_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            14769..15035
                     /locus_tag="VU722_001775"
     CDS             14769..15035
                     /locus_tag="VU722_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1772695.1"
                     /translation="MEGCPSEFFSKEEILESDMRVAIMSELIEARHEQGISQKKLEEF
                     SGVSQPVIARMETGKTSPQLDTVLKVLSSLGKTLVVVSLEQRKS"
     gene            15403..17652
                     /gene="metE"
                     /locus_tag="VU722_001776"
     CDS             15403..17652
                     /gene="metE"
                     /locus_tag="VU722_001776"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU1772696.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEILEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLNLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVATYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            17716..18582
                     /gene="metF"
                     /locus_tag="VU722_001777"
     CDS             17716..18582
                     /gene="metF"
                     /locus_tag="VU722_001777"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU1772697.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPYFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
BASE COUNT         5905 a         3256 c         4003 g         5782 t
ORIGIN      
        1 ttctaagttg gatgaagttg aaagattata ggcgataatt tcgatattaa agccatctaa
       61 aactggtgat aagtaaagct tttgagtact tgctggaatg gcaaattctg tcacatctgt
      121 gtagcacttt tccattgttt tagagccttc aaattgacgt tgaatgagat tctctgcctt
      181 tttgccaaca tctcctttat gagaagaata ttttcgtttc tgttgcattt tagcttgtaa
      241 attgagtact ttcatcaagc cttgaactct tttatgattt accagataac cacgatttct
      301 tagttctaaa taaattcgac gataaccata atttcccttg tgttcgataa agatggattg
      361 aatttcagct ttaagctctt ggtccttatc tggtttatct agctgtttca agtgatagta
      421 gtaggtcgaa cgagctagtt taatggcttt tagaagaaga gctaacgaaa actcagtcat
      481 taattcttga acaatttctg tctttcttct ttctcttttt cctccttcaa tcggagttct
      541 cttaactttt ttaggatggc attctccgct ctcaggtact cattttctga ttgaagacgt
      601 tctaattctg tcctctcttc aggtctcgtt tttggattac gtcccatttt aggtactctc
      661 cctcttggtt tctcaacaat agtatacccg tttttcctgt attgtgctag ccagttaaga
      721 agtatcgtac gacttgggag accgtattca agagaaactc tatctttagt ccagccttca
      781 tgtcagactt tatgaatcat ttcttgtttt aaatcaggag aatagtaacg attttttcct
      841 tttttgccga actctattcc gtaacgatca atcaatttaa tcatgtacct aagattagaa
      901 ttgtttatcc caaatttatt tgaaagcttc tctaagctat atccttgttt tctaagttca
      961 tagatctgaa ctttatcatc ataagttaat ttcataataa aaacacccca aaagttagat
     1021 tttttctgtc taacttttgg ggtgtagttc atgtacacct gatatgatgc gttttttgaa
     1081 ttttatagac tgctcgttta aactctattt acctcgtaca ttccggagcg agatggacta
     1141 ttggtcgcat acaaaatgag tgttattcgg attttatttt cgtgtacaat ttcagctatt
     1201 cttgttataa tcagcctata ggaatcaagg aggtgactct tatggctgtt tttgtgtctt
     1261 tggatggaat tgtggtagaa gtacttgatg tcttttcttc ttttaatggg gatagtgagt
     1321 ttttcttgtg taaacgtctt aaagacaaga gtcagtttgt tatggaacgc tctcagttcg
     1381 aggagatgtt ccaacttcaa agtagtcgct tgacgacgca agaaaaatta caattgttta
     1441 cctctgtgtt tgctggccgt tatgatgttt atgctaagag ttttatcaat gatcaaggga
     1501 aaattcagta ttttccttcc tatgattatg gttggaagca gttgctatct gaaaaacgga
     1561 gtttccagac attgacggat tccgttttga aatctcattt tcgtggggag acagctatcg
     1621 gtatctttcc tatgcactta gatgatagct gtcatttttt ggtactggat tttgatgaag
     1681 gagattggaa agaagctggt ttaaccattc gaagaatagc cagggaacgc cagatggaag
     1741 cccatttaga gatttctcgt tcgggtcacg gactccatat ttggttcttc tttgaggaag
     1801 cgattccgag tcgagaggct cgcttgtttg gaaagaaact gatagaactg gcaatgcagg
     1861 aaagtatgca actgtccttt gattcttttg atcgcatgtt tccaaatcag gatgtccttc
     1921 ctaagggggg gatttggaaa tttgattgcc ttgccttttc aaggagaagc ttaccatcaa
     1981 gggcgaacgg tctttgtgga tgaacagttt cagccttatg aagaccaatg gaggtatcta
     2041 caagaaattc agagggtttc aactgctaaa gtggcactgt taatccaaga agagttaggc
     2101 aagcaagaat tggacaagga gttgaagatc gtcttatcca atatgatcca acttgaaaaa
     2161 tcgtctgtga cacccaagac actgtttttc ttgaaaaata tggcttcatt ttctaatccc
     2221 gaattttatt taaagcaggc tatgcgacag ccaacctatc aaattcctga gagaatgtat
     2281 ttatttggag aatccgatca ttatttatgg ttgccaagag gtttgctgta tccattgcaa
     2341 gataaattta agcaggtatc tgtggaagat aggagaaagg tacaaaggtc tattagcgtg
     2401 gaatttaagg gagaactcac ttttgagcaa gagttagccc tgtcagatat gacttctaaa
     2461 gaaaatggtt tacttcatgc ggagactggt tttgggaaga ccgttttagg tgctgctctt
     2521 atctctgaac ggaaaacaaa aacaattatt ctagtccata ataagcaact cttagaccaa
     2581 tggctagatc gcttaaactg ctttttgact ttcgaagagg aggaggctat ccgttatacg
     2641 gcatcaggtc gtgaaaaggt aatcggctat gttggacagt acggtgggac taagaaatgg
     2701 cttagtaaac tggttgatgt cgttatgatt caatctctat ttaagttgga aaatagtcaa
     2761 agtcttttgg atgagtatga gatgatgatt gtggatgagt gtcatcatgt ctctgccttg
     2821 atgtttgaaa aagttgttgc tcagtttaga gggaagtatc tttacggttt gacggctacg
     2881 cctgagcgta agaatggtca tgagcctatt gtttttcaga gaattggtga gatactccat
     2941 actgctgata agagggaaac ggattttaaa cggcaattgc aattaagatt cacttctttt
     3001 ggtcatttgg agattgaaaa gaccaaagca agtaatttta tacagcttag tgattggatt
     3061 gctactgact cagcgaggaa tcagttgatt ctcaaggata ttctagccca agtggcagaa
     3121 ggacggaata tcttggtttt agttaatcga attcaacaga tagatgtctt tgaaaagtta
     3181 ttgaaagaga aagaggttga tgactgttac attattagcg gaaaaaccaa agtccgagaa
     3241 agaacgagtt tactggagac gttagaacag ttagataaag ggtttgtttt gttgtctact
     3301 ggaaaataca ttggcgaagg ttttgactta cctcagttgg acacgcttat cttggcagca
     3361 cccttttctt ggaaaaataa tttaattcag tatgcaggtc ggattcatag aaactacaag
     3421 gataagtctt tggtgcgtat tttcgattat gtggatattc atgttcctta tttagaaaag
     3481 atgtttcaga aacgacaagt agcttatcga aagatggatt atcgtgtcat cgagggtgag
     3541 gagaaacaat tcgtttatgt tgatagtaga tatgagaagg tgttgagaga ggacttagca
     3601 ggggaaagac aggaatgtct gcttatttta ccttatgtgc accagacaaa actgatgaat
     3661 tttctaaaag aatttaggat tagtcaaatt gagatatgta taccagagac ggttgcaaat
     3721 aaagcatggc tagaccagtt gaagagcaag aaaattaaag tatcttttac tcaaataaaa
     3781 atagtcatgc ctattctttt ggtgaataag actattgttt ggtatggcgc aatgccatta
     3841 ttagggaagg tagatgaaat gaccatacta cgtttggaat cagctagtat agcttctgaa
     3901 ctagtggcag gtttacgata gagaaaattt ttaaaaattt ctatgtatga ttttcatttc
     3961 tttagtgaga ctgttgccat tatcacattc gaatcacaca aaataaaaaa atttctacaa
     4021 gtacttgaca aatagattga aatatcataa aatgaaaatg gttacagagt tattaatgat
     4081 ttaagcttca tgtcaccatt aaaaattgaa ataaaaggat gttatcacta atacaagtga
     4141 gcaggaacct atttaatcac atcggaagaa gtttcttgat gtttttaagt aggttccttt
     4201 tattttaaaa gggaaattta tgatcataaa acgaatacta aaccacaatg ccgtaattgc
     4261 gcaaagtaaa aaagatatcg atattcttct ttttggaagg ggaatagctt ttggaagaaa
     4321 aactggagat aaagtaaatc caattgatat tgagaaaagt ttttttctca aaaatagaga
     4381 taatatgacc cgttttacag agatgtttat taacgttcct ttggagttgg tgtacatcac
     4441 cgaaaaaata attaatctag gtaaaataac attaggtaat aattttgatg agattatcta
     4501 tataaatcta acggatcata tttcttcgag tatagaacgt tataaagaag gagttattat
     4561 ttcgaatccc ctacgctggg aaatctcgaa atattataaa gaagaatttg agcttgggaa
     4621 aagggcttta caaataataa aaaaagagtt aggtattgaa cttccaattg acgaagctgc
     4681 attcatagcg ctacattttg ttaatgctaa tttagaaaat aattttcaag agtcgtataa
     4741 aatcactgaa ataattatgg gaattgagaa aatcattcaa gatttctatt gtactgagtt
     4801 taaccaagat tctattgatt attatagatt cataactcat ataaaattat ttgcccatcg
     4861 cttggttgaa aatacaactt attgtgacga tgatgatgaa gacttgttag cattaatgaa
     4921 aaataaatat cctagagaat atgaatgtgg tgaacaggtg gcaatgttta tacaaactga
     4981 gtacaattat ttgctgactt ctagtgaatt agtttatttg atggctcata ttcgtcgctt
     5041 aacaaaaaat ttagattaat agaataggag aataccatga gttataaaga taaggtacaa
     5101 aaaatcttcg atgtaattgg aggtgaaaaa aatgtcaata gagttaccca ttgtgtaaca
     5161 cgtttaagat tagaattaaa agatgaaaat ttagtcaatg atgatgatgt gaagaagata
     5221 ccaggtgtaa taggtattat gaaaaagaat ggacaatatc aaattatact tggtaatgat
     5281 gtagctaatt attataaaga attcgttaaa cttggcaatt ttgaatccga ttcagttgtt
     5341 caagggcaca aagggaatat tttagaaaga atcattgagt atatcgctgg ttccatgact
     5401 ccaatcattc cagcaatgtt agggggaggt atgctgaaag tcttggtaat tattttacca
     5461 atgcttggta tattgcaatc agattctcag actattgctt ttttgacatt ttttggggat
     5521 gctccatatt atttcttacc gctgttatta gcttattctg catcacaaaa attaaaagta
     5581 acatctacat tagctatgtc tgtagcaggt gtacttctcc atccaaattt tgttcaaatg
     5641 gtgcaatcag ggaatcctct tagtttattt ggtgtacctg tgacaccagc tagttatggt
     5701 tcgtcagtcg ttccaattct tattatggtt tggttgatga aatatattga aaaaatgatt
     5761 gctaaattaa caccagctgt tactaagagt tttttgcaat ctacgctagt attattagta
     5821 tcaagctgta ttgccttagt tgtagtcgga cctattggag taattgttgg tcaaggatta
     5881 tcaaatctag ttgggcaaat gtatggtgta gctggatggc ttacattagc tattcttggt
     5941 gctattatgc catttattgt tatgactgga atgcattggg cttttgcacc tatttttttg
     6001 gcggcatcta ttgctactcc agacgtatta attcttccag caatgttagg gtcaaactta
     6061 gctcaagggg ctgcttcgat ggctgttgca ttaaagagta aaaataataa tacaaaacaa
     6121 attgcttttg cagcaggttt ctcagcctta tttgcaggaa ttaccgaacc tgcagtatat
     6181 ggtgtgactt taaaatataa aaaaccgctt tatgcagcta tgattggtgg tggattagcg
     6241 ggattatttg caggtcttac tagtgttaaa gcgtatctat ttgctgtccc atctttgata
     6301 gcgttgcctc aatttattta ttctgatgta ccatcaaata ttgtaaatgc tttaattgtg
     6361 gcggttattt cggttgttat tacctttgta ttagcttata tatttggaat cgatgaagaa
     6421 gagagttcta gcaatttaga agttaaagct ggagtttcaa ataaaaaaat gatattttct
     6481 cctatatcag gagaaatcat tccgttaagc gatgtccagg ataaaacatt ttcagataaa
     6541 ctaattggag acggggtagc gattatccca agtgaaggta aggtttatgc accatttgat
     6601 gggaaaatta caaatatttt tccgactaag cacgcaattg gattgaagag tgatgagggt
     6661 gttgagttac taattcatat tggattagat actgttgagc taaaaggtca aggttttatt
     6721 agtcatgtag aagaaggaga cagagttttc aaaaatcagt tgatttttga aatggacttg
     6781 aatttaatca agactaaagg ctacgaaaca gttacaccag taattgtaac gaataccaat
     6841 gattttctag atgtattagt attacctaat aatcagacaa tcgagcattc taaggaatta
     6901 ctggtaatat tataatggag gaaagttatg accatttttc cagatgattt tctttggggt
     6961 ggagctgttg cagctaatca agtagaggga gcatataatg aagatggtaa gggcttatca
     7021 gttcaggatg tgttacccaa aggtggatta ggagaagcaa cagaaaatcc tacagaagat
     7081 aacttaaaat tgttaggtat tgatttttat cataaatata aggaagatat atccttgttt
     7141 tctgaaatgg gctttaatgt ttttcgtact tctattgcat ggagtagaat ttttccaaaa
     7201 ggagatgaag aagaacctaa cgaagctggt ttgaaatatt atgatgaatt gtttgatgaa
     7261 ctacatgctc acgggataga gccacttgta actctttcac actatgagac tccattatat
     7321 ttagcaagaa aatatcatgg atgggttgat aggagaatga ttcattttta tgaaaaattt
     7381 gctcgaacag ttttagaaag gtataaagat aaagttaaat attggcttac atttaacgaa
     7441 gtaaactctg ttttggaatt accatttact agtggaggaa tagatatacc taaggagaat
     7501 ctttcgaaac aagaattata tcaagctata catcatgaat tagtcgcctc aagtttggtt
     7561 acaaaaattg ctcgtgagat taattcagag tttaaggtgg gatgtatggt attagctatg
     7621 ccagcttatc caatgactcc aaatccaaaa gatgtatggg cgactcatga gtatgagaat
     7681 ctaaattatc tattttcaga tgtgcatgtt agaggttatt atccgaatta tgcaaaaaga
     7741 tattttaagg aaaatgacat taacatagag tttgcagctg aagatgcaga gttattaaaa
     7801 aattatactg tagatttttt atcctttagc tattacatga gtgtgactca atctgctctt
     7861 ccaacacagt ataattcagg agaagggaat attattggtg gtttagtaaa tccttattta
     7921 gagtcttcag agtggggatg gcaaattgat ccaattggac tacgtataat tttaaataga
     7981 tattatgacc gttatcaaat cccattattt atagtagaaa atggattagg tgctaaagat
     8041 caactaataa aagatgaact taataactta accgtccaag atgattatag aattcagtat
     8101 atgaaagaac atttattgca agttgctgaa gctctacagg atggtgttga aattatgggc
     8161 tatacgtctt ggggatgtat tgactgtgtt tctatgtcca ctgcacaact ttctaaaagg
     8221 tacggtctca tttatgttga tcgaaatgat gatggaaatg gcacattcaa tcgatataag
     8281 aaaatgtcct ttacttggta taaaggagtg attgaatcaa atggagaatc cttattcaaa
     8341 tagtttgttt attgatgatt agatattatc acggttaagg caacatctca ttaaatatga
     8401 aataaagagg tttggaagac atcaaattct aaacctcttt attttatagg gggattaatt
     8461 aatttaattt tgttacagag agccgattat aaatagttaa cttaggatag attggttata
     8521 tatagtagac tgaatctaaa atagtacgaa acaattgcta aaacatttat agaaattaat
     8581 tttactttcc caatcgattt gttttcatct tatttcaatc cgctataaag ttagataaga
     8641 ataagctaac aagcagaagt aagataggtc ttgcaagaat ggtaaaaatc tgataaacta
     8701 agtagtaatt gaataggaat ctgaaagact agtagcccaa gggaagtata tcagggagga
     8761 gagccgtgac tgcaagctct ctatatgaaa gctgggtgaa ttcacttgcg catggattta
     8821 gaaatgaagg tctgacttgt cagatgaaaa cggatggtac cgcgtgtcaa cgctccgagt
     8881 ggagtttttg gcatgtggtt ttctttttat ctacgagaga ctgatggagg aaatatgtca
     8941 actattgaag aacaattaaa agcgcttcgc gaagaaacgc tggctagctt gaagcagatt
     9001 actgctggaa atgaaaaaga gatgcaagat ttgcgtgtct ctgtccttgg taaaaagggt
     9061 tcgctcactg aaatcctcaa agggatgaaa gatgtttctg ctgagatgcg tccaatcatc
     9121 gggaaacacg tcaatgaagc tcgtgatgtc ttgacagctg cttttgaaga aacagctaag
     9181 ctcttggaag aaaagaaagt cgcggctcaa ctggctagcg agagtatcga tgtgacgctt
     9241 ccaggtcgtc cagttgcgac tggtcaccgt cacgttttga cacaaaccag tgaagaaatc
     9301 gaagatatct tcatcggtat gggttatcaa gtcgtggatg gttttgaagt ggagcaagac
     9361 tactataact ttgaacgtat gaaccttcca aaagaccacc cagctcgtga tatgcaggat
     9421 actttctata tcactgaaga aatcttgctc cgtacccaca cgtctccagt tcaggcgcgt
     9481 gctatggatg cccatgattt ttctaaaggt cctttgaaga tgatctcgcc agggcgtgtc
     9541 ttccgtcgcg atacggacga tgcgacccac agtcaccaat tccaccaaat cgaaggcttg
     9601 gtagttggga aaaatatctc tatggctgat cttcaaggaa cgcttcagtt gattgtccaa
     9661 aaaatgtttg gtgaagagcg tcaaattcgt ttgcgtccat cttactttcc attcacagag
     9721 ccatctgttg aggtggatgt ttcttgcttc aaatgtggtg gagaaggctg taacgtatgt
     9781 aagaaaacag gttggatcga aattatgggg gccggtatgg ttcacccacg tgtccttgaa
     9841 atgagtggta tcgatgcgac tgtatactct ggctttgcct ttggtcttgg acaagagcgt
     9901 gtagctatgc tccgttatgg aatcaacgat atccgtggat tctaccaagg agatgtccgc
     9961 ttctcagaac agtttaaata atgattagaa aagtagaaat ggcagatgtt gaggtgttgg
    10021 ctaaaattgc caaacaaacc tttcgtgaaa cctttgcgta tgataatacg gaagagcagt
    10081 tacaggaata ctttgaagag gcttatagtc tgaaaacttt gtcaactgag ttgggaaatc
    10141 ctgactctga aacctatttc attatgcatg aggaggagat agctggtttt ctcaaagtca
    10201 actggggaag tgctcaaact gagagagaat tagaggacgc ttttgaaatt caacgcctct
    10261 atgtgctaca aaaattccaa ggatttggac taggtaagca actgtttgaa tttgctcttg
    10321 aacttgctac aaaaaatagt ttttcttggg cttggttagg tgtttgggag cataatacaa
    10381 aagctcaagc gttttataac cgatatggtt ttgaaaaatt tagccaacat cattttatgg
    10441 ttggtcaaaa agtagatacg gattggttac tgagaaagaa attaaggtaa gaagatgatt
    10501 cttctattga aatgatagga aaggaaaaga actagagtga caactgtcat tctggagaac
    10561 taaattatgc ttgtatctta taaatggtta aaagaattgg tggacattga tgtgccatca
    10621 caggagttgg ctgaaaaaat gtcaaccaca gggatcgagg tcgaaggtgt cgaatcacca
    10681 gctgccggtc tttcaaaaat tgtcgtcggt gaggtcttgt cttgcgaaga tgtgccagaa
    10741 actcacctcc atgtttgtca ggttaacatt ggcgaagaag aagctcgtca aatcgtttgt
    10801 ggtgccccaa atgtgcgtgc aggcatcaag gttatggtgg ctcttccggg agctcgtatc
    10861 gctgacaatt acaaaatcaa aaaaggaaaa atccgtggct tagagtcact tggaatgatc
    10921 tgttcacttg gtgaattggg tatttctgac tcagttgtac ctaaggaatt cgcagatggt
    10981 attcaaattt tgccagaaaa tgccgttcca ggtgaggaag tcttctcata tctagacttg
    11041 gatgatgaaa tcatcgaact ttctatcaca ccaaaccgtg cagatgccct ttctatgtgt
    11101 ggggttgcgc acgaagtagc agccatctat gacaaggcag tcaactttaa agaatttact
    11161 ttgacagaaa caaatgaagc tgcgacagat gccctttctg tgggcattga gacagacaag
    11221 gcaccttact atgcggcccg tatcttggac aatgtgacca tcgcaccaag tccacaatgg
    11281 ttgcaaaacc ttctcatgaa cgaaggcatc cgtcccatca ataacgttgt agacgtgaca
    11341 aactacatcc ttctctactt tggtcaacct atgcatgcct ttgacttgga tacctttgaa
    11401 gggactgaca tccgtgtgcg tgaagcgcgt gctggtgaaa aattggtgac cttggacggt
    11461 gaagaacgtg acttggacgt gaatgaccta gtcatcactg tcgcagacaa gccagtagcc
    11521 cttgcaggtg tcatgggtgg tcaagcaaca gaaatctctg aaaaatctag tcgtgttgtc
    11581 cttgaagctg ctgttttcaa tggcaaatct atccgtaaga caagtggtcg cctgaacctt
    11641 cgttctgagt catcttctcg ctttgaaaaa ggaattaatg tggcaacagt taatgaagcc
    11701 cttgatgcgg cagctagcat gattgcagag cttgcaggcg cgacggtgcg taagggtatc
    11761 gtttcagcgg gtgagcttga tacttcagat gtagaagttt cttcaaccct tgttgatgtt
    11821 aaccgtgtcc tcggaactga gctgtcttat gctgatgtag aagacgtctt ccgtcgtctt
    11881 ggctttggtc tttctggaaa tgcagacagc tttacagtca gcgtaccacg tcgtcgttgg
    11941 gatatcacga tcgaagctga cctctttgaa gaaatcgctc gtatctatgg ttatgactgc
    12001 ttgccaacta gtctaccaaa agacgatggt acagcaggtg aattgacagc cacacaaaaa
    12061 ctccgccgtc aagttcgtac tattgctgaa ggggcaggct tgacagaaat catcacctat
    12121 actctaacaa ctcctgaaaa agcagttgag tttacggctc aaccaagtaa ccttacggaa
    12181 ctcatgtggc caatgacagt ggaccgttct gtcctccgtc aaaatatgat ttctggtatc
    12241 ctagataccg ttgcttacaa cgtggctcgt aagaacaaaa acttggccct ttacgagatt
    12301 ggaaaagtat ttgaacaaac aggtaatcca aaagaagaac ttccaaatga gatcaacagc
    12361 tttgcctttg ccttgacagg cttggttgct gaaaaagatt tccaaacagc agcagttcca
    12421 gttgatttct tctatgctaa aggaatccta gaagcgctct ttactcgctt gggactagaa
    12481 gtgacctata cagcaacagc tgagattgcc agccttcacc caggacgtac agcagtcatt
    12541 tcactcggtg accaagttct tggttttctt ggccaagtgc atccagtcac tgctaaggcc
    12601 tacgatattc cagaaacgta tgtggctgag cttaaccttt cagctatcga agctgcgctt
    12661 cagccagcga ctccatttgt agaaatcacc aaattcccgg cagtcagccg tgacgttgcc
    12721 cttctcctca aggcagaagt aactcatcaa gaagttgtag atgctatcca agctgccggc
    12781 gtgaaacgtt tgacagatat caaactcttt gacgtcttct caggtgagaa attgggactt
    12841 ggtatgaagt ccatggctta tagcttgacc ttccaaaatc cagaagatag cttaacggac
    12901 gaagaagtcg cacgctatat ggaaaaaatc caagcatcgc tcgaagaaaa agtcaatgca
    12961 gaagtgcgtt aaacgatagt atgatacaaa ttccccctct agtttatgaa cactagaggg
    13021 gtgattttat ataaaataat taaaatgtga tttctgtaaa aatacatcta tgatcagagt
    13081 tttgaaaact tacaatgtct aaatctctaa catagtagtg gtttttaggc aataagatat
    13141 gatctatcgt tgcattaaaa agttttggac tttggctatt ccaagttcct ctttcaaaag
    13201 gtggaagtgc attcaatgcg tccctatgag agcttatttt tgcaagtgct ccatgacgca
    13261 tagttgcatt aaaatcacct gcaataatag cctttggata ttttgaagcc aattgattat
    13321 gaatgatgtt taagtcttgc ttccagattt ccattaaacc tggcagagga ggagcagtat
    13381 gcaaggcaat gatatctggt atattttgtt ttctcgaatg taatacaatt gtcccgaacc
    13441 gtgttgtatg aaaagtttta gcttctgtat agaaaccata acttttcttg acaatcacag
    13501 tcacaggagc tattccatta ttggtaggtg gagaagtgaa aatatcatag ttggccatag
    13561 aaagtccaac ttgatgaaac aatagtttga ttctctggtt ttcttgctca cctctgatat
    13621 tggtagctag ttcagggaat atagccatat cggcatcaaa atggctaaaa attcgctcaa
    13681 tatgttgtgc ttctatttga ttagcgacgt tccaagttac taattttaag gttttagtct
    13741 tatttgatgc agaagaaagg gttttatctg ttccaaataa tagtaatatg agcgatagta
    13801 agagcaaaat gccagagtaa aaccgtattt gtttattttt cttgtaaaaa gataggaaaa
    13861 aaaaataaga aacttaaaat agcagccata gttgcagtag ctaaggggaa ggcataaatc
    13921 tgtgccaaga taggttgggt agatagccaa atgttaagat tagaagatgg aaaaaaagaa
    13981 taagctatga tagggataac aaagagaatg accgaaaggg cagagagaaa tgttttaatc
    14041 attgtgtgag tacctcaatt tgcaatggtt gctcggagct aatgtgactt tgtgacttta
    14101 cttgatgata ttctttttat tgtcttcctt atagattaag tacaacccaa gtaaaaaaag
    14161 ttcaatttaa gattgaaatg attaaaaggc acagaaatgc aagacaatta tactacaaaa
    14221 ggcaaacatt tgacaatcga tagccgtcgc ttaatcgaac gatggaaaaa agaaggaaaa
    14281 tcaaatagag aaattgcctc tctacttgga aaagctcctc aaactatcca cactgaaatc
    14341 aagcgtggga cagtccgaca atgtcttgga aaagggcgtt tcaaagagat ttattctgcc
    14401 gactatgctc aacagtctta tgaaaacaat cgcaagcgct cggtcaagaa atcaagcttg
    14461 accaaggaac taaaggaaaa gcttctccac tatcataacc aaaaattttc gcctgaaatg
    14521 atggtgatgg ctaaaggggt taacgtggga atttcaatca tttactattg gattcatcat
    14581 ggaaaattgg gattaagcaa acaggatctg ctttacccta gaaaaggaaa agcgcttaag
    14641 aaacaagcta gtcccaactt taaatccgct ggtcaatcta tcaaatcata attcgctcat
    14701 tttttcaaaa atacatagac gtaaaagaaa gagggttaag tgatgaagaa tagtgctatt
    14761 gggagtaatt ggaaggatgt ccatctgagt tctttagcaa ggaggaaatc cttgaaagtg
    14821 atatgcgagt ggctattatg agcgagttga ttgaggctag gcatgaacaa ggaatcagtc
    14881 aaaaaaagct ggaagaattc agtggagtaa gccagcctgt catagctagg atggaaacag
    14941 gcaagactag ccctcagttg gatacagtct taaaagtctt atccagtttg ggaaagacac
    15001 tagtagtagt ctcactcgaa cagagaaaga gttgattaga gtagacttat actcaatgaa
    15061 aatcagagag caaactagga aactagccgc tgactgtact tgagtacggc aaggcgacgt
    15121 tgacgcggtt tgaatttgat tttcgaagag tattatagtc ttttctaata acaagccata
    15181 gtcacttata agaattacta ataacatgtt ttagtattct aattggaata tagctgtaaa
    15241 gtaagaatta caaaggattt gagacgtttg cttcaagtct ttttcttttg tccgaaacag
    15301 agatatagtt tcaaactata tcaaacccta attttttaca attatacaga cgctttcttt
    15361 tctgttaaga tagtttcaac aacaaatttt ggaggacaca tcatgtcaac tacaatcatc
    15421 ggtttccctc gtttggggga attccgtgaa ttaaaattta caactgaaaa atactttaga
    15481 aaagaaatct tagaggaaga acttttagca gcagcaaaag acttgcgtgc taaacactgg
    15541 aacattgtca aagaaaaagg tatcactgag attccatcaa atgacttttc tcactatgat
    15601 aacttcctag atgcagcttt ccttttcaac gtagtacctg catccgttca aaacttgaac
    15661 ttgtctgacc ttgagcgcta cttcgctttg ggacgtggtt accaaggaga aaaaggggac
    15721 gttcgcgccc tcccaatgaa gaaatggttt aacactaact accactacat cgttcctaaa
    15781 tttgaaaaag acactcaagt caaacttgca ggtcacaaga tttttgatga gttccaagaa
    15841 gccaaagaac ttggattgaa cactcgtcct gttcttgtag gtcccttcac tttccttcaa
    15901 ttgtcagact ttgaagaagg cgtgaaagca gacgacttcg tagatagctt agtggctact
    15961 taccaagaag tttttgctaa attggctgaa cttggtgcga ctcgcatcca attggatgaa
    16021 gcggctcttg taaaagactt gacagctgaa gaaaaagctc tcttcttgaa cctttacaac
    16081 aaactcttgg ctgacaaaaa aggtcttgaa gtcttgcttc aaacttattt cggtgatgtt
    16141 cgtgacgtat acgctgacct tgtaaacttg ccagtagatg ctatcggtct tgactttgtt
    16201 gaaggtaaga aaactcttga actcgttaaa ggtggcttcc cagctgacaa gactctctat
    16261 gcaggtattg tcaatggtaa aaacatctgg cgtaacaact acgaaaagag cttggctgtt
    16321 cttgagcaaa tcccagctga aaacatcgtt ttgacaagct cttgctcact tcttcatgtg
    16381 ccatttacaa ctgctaatga agaatttgaa ccagcactct tgaaccactt tgcctttgca
    16441 gttgaaaaat tggatgaaat ccgtgacttg gatgctatcc gcaatggtca aggttcagaa
    16501 gctcttgcag ccaacaaaga actctttgcg actgagcgtg ttggtgaaaa tgctgaactt
    16561 cgtgcgcgta tcgctggctt gacagacgca gactacactc gtttgccagc ctttgcagaa
    16621 cgtgaagcta tccaagaaga agctttcaaa cttccagctc ttccaacaac aacgattggt
    16681 tcattccctc aaacaaaaga agttcgtgcc aaacgtttgg cttaccgtaa aggtgaattg
    16741 tctcaaaaag agtacgatgc tttccttgct gaaacgattg acgaatggat caagtggcaa
    16801 gaagatattg actttgatgt ccttgttcac ggtgaatttg agcgtaatga catggttgag
    16861 tacttcggtc aaaacttgtc aggatacctc ttctctaaaa atggatgggt acaatcatac
    16921 ggtatgcgtg gggtaaaacc accaatcatc tggggtgatg tcactcgtct taaccctatc
    16981 actgttaaat ggtctagcta tgcacaaagt cgtacaaaca aacctgttaa aggtatgttg
    17041 actggacctg ttaccatcct taactggtca ttcccacgtg aagacatctc tatcaaggat
    17101 tcaactctcc aaatcgccct tgctatcaag gatgaagtac ttgaccttga agctgctggt
    17161 gtgaaaatca tccaaatcga cgaggctgct cttcgtgaaa aattgccact ccgccgtagc
    17221 gactggtacg aagactacct tgactgggct attcctgcct tccgcttggt acactcaaca
    17281 gtagcgccag acacacaaat ccacactcac atgtgttact cagaatttac agatatcatc
    17341 ccagctatcg ataacatgga tgcagacgtt atttcctttg aagctagccg ttcaaacctt
    17401 gaaatcttgg acgaactcaa agcgaaaaac ttccaaacag aagtgggacc tggggtttac
    17461 gatatccact cacctcgtgt accaaatgaa ggcgaaatcg acaacacaat cgaagccatc
    17521 cttgctaaag tgccaagcaa gaaagtttgg atcaaccctg actgtggttt gaaaacacgt
    17581 ggtatcccag aaacaaaaga aagcttgatc cgccttgttg aagcagctaa agctgcgcgt
    17641 gagaaattgt aagattggat ttctctccat acagtggttg ttcaaaaaga aatcaactag
    17701 aaaaggttat tacatatgtc acgccaaaca ccgtcactct catttgaagt gttccctcca
    17761 aacccagccg tgggtaatga taacattatt tcagccttgc aggatatgca ggaattggct
    17821 ccctatttta tcagtgtaac tgccagcaat aataaattta atatcaagga aacgacggtt
    17881 cgtttggctg actttatcca aaatgatttg gcgattccga ccattgccca cttgccagct
    17941 atttatctaa ctaaggacaa ggttgctgaa actattgctg acttggacaa agttggggtg
    18001 cagaaaatct tggctcttcg tggggatatt attccagacg tggaaccaca aaaggatttc
    18061 cgctatgcaa ccgacttgat tgagtttatc aaggaacaaa cccctcactt tgatattatt
    18121 ggagcttgct atccagaagg gcatccagat tcgccaaatc agatttcaga tattcaaaat
    18181 cttaagaaga aagtggatgc aggctgttcg agcctcgtaa ctcagctctt ctttgacaat
    18241 gagcgcttct atgattttca ggacaagtgt atcttggctg ggattgatgt tcccattcat
    18301 gcaggaatta tgccaattct gaatcgaaat caggctctcc gactcttgaa gacttgtgag
    18361 aatatccatc ttccacgcaa atttaaagcc atcttagaca agtatgagca tgaccctgag
    18421 tcgctcagag cagcaggact tgcctatgca gtggaccaaa tcgtggactt ggtaactcag
    18481 gatgttgccg gtgtgcatct ctatacgatg aataatgctg atacagcaaa atacatccat
    18541 caagcaaccc atgccttgtt taatcaccag tctctaggat aataaaagca aaccattctt
    18601 ctcaggtgag gggaatggtt cctttttaat ggtaaagacc tcacttttta agaaaaatat
    18661 gataaaataa attctgtacg tacttgatac aaagatgaag gtattaaata atacaatgca
    18721 tttaaactgt aagatttaac gacacgagtg agtcaaatcg atgttatttg acgagagagt
    18781 tagtaaagca tttagctaat cgcccgatag cgattagcgt gaaagcttta gatattttag
    18841 tattaaacct ttctaatgat gtatcttgaa aactgaactt gcctacaact ctgtggaaaa
    18901 agataaatct ccctaggagc agtcgctccg tcgttcgatt tcctat
//
LOCUS       DAVFJR010000042        18537 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVFJR010000042 DAVFJR010000000
VERSION     DAVFJR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.043"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VU722_001778"
     tRNA            1..73
                     /locus_tag="VU722_001778"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VU722_001779"
     tRNA            87..160
                     /locus_tag="VU722_001779"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VU722_001780"
     tRNA            171..260
                     /locus_tag="VU722_001780"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VU722_001781"
     tRNA            271..344
                     /locus_tag="VU722_001781"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VU722_001782"
     tRNA            348..420
                     /locus_tag="VU722_001782"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VU722_001783"
     tRNA            440..510
                     /locus_tag="VU722_001783"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VU722_001784"
     tRNA            546..619
                     /locus_tag="VU722_001784"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VU722_001785"
     tRNA            626..713
                     /locus_tag="VU722_001785"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /gene="birA"
                     /locus_tag="VU722_001786"
     CDS             complement(839..1774)
                     /gene="birA"
                     /locus_tag="VU722_001786"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HEU1772698.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDIDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VU722_001787"
     CDS             complement(1771..2631)
                     /locus_tag="VU722_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU1772699.1"
                     /translation="MLVFSEYQTGTINLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VU722_001788"
     CDS             2739..4901
                     /locus_tag="VU722_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU1772700.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVIDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVKKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADESKKVDIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNIDAIARLPIQYGSSYLYPTISMGD
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVSLSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VU722_001789"
     CDS             4993..6252
                     /locus_tag="VU722_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1772701.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGVGDLAWSISATTKHPKEANAFVEYMTRPE
                     VIQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VU722_001790"
     CDS             6266..7132
                     /locus_tag="VU722_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1772702.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VU722_001791"
     CDS             7146..7979
                     /locus_tag="VU722_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1772703.1"
                     /translation="MKQDGRKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNFVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8291..9733
                     /gene="gtfA"
                     /locus_tag="VU722_001792"
     CDS             8291..9733
                     /gene="gtfA"
                     /locus_tag="VU722_001792"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU1772704.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYVEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPIQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYYFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9871..11064
                     /locus_tag="VU722_001793"
     CDS             9871..11064
                     /locus_tag="VU722_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU1772705.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11751..13730
                     /locus_tag="VU722_001794"
     CDS             11751..13730
                     /locus_tag="VU722_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772706.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13797..15293
                     /locus_tag="VU722_001795"
     CDS             13797..15293
                     /locus_tag="VU722_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772707.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15293..16219
                     /locus_tag="VU722_001796"
     CDS             15293..16219
                     /locus_tag="VU722_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1772708.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16228..17295
                     /locus_tag="VU722_001797"
     CDS             16228..17295
                     /locus_tag="VU722_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772709.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKICEKMGFAHLAD"
     gene            17306..18232
                     /locus_tag="VU722_001798"
     CDS             17306..18232
                     /locus_tag="VU722_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1772710.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(18307..>18537)
                     /locus_tag="VU722_001799"
     CDS             complement(18307..>18537)
                     /locus_tag="VU722_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772711.1"
                     /translation="HPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFRKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5386 a         3318 c         3943 g         5890 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataattat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtttgt aactctcttt tttattttta gagacaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag tacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg atatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttgtat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgatg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctca ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagataaga ttgatcagaa atttgagaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtaggacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggttgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaatagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttaaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagcccctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatt ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aatctaagaa agttgacatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctgatta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct atcttatcat gagattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta cgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat acgctatttc ccacaagtct gggctagtga taatattgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggatcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccatg
     4501 tagcaatgat gggaaatttg ggctatgagc ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgcatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttagc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagattttt tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgtg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcata
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattacg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 tttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattgggaat gcccttcata ttgaatttct ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatagtcttt atcctagccc taaaaggtgg gctgactgcc tttgatcaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgga agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtt ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactt tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgtact tgagtacggt
     8041 aaggtgaagc tgacgtggtt tgaatttgat tttcgaatag tataagaaga gctcatggaa
     8101 tctatagtct ttgacacagc ggaagagttc agcttgttga taattctatg tagaaaacaa
     8161 gaaagtagta ctttgtttat cacagtctat attagtacga gtttgatgat aaatagagat
     8221 ttaaaatgaa tttgatttac gaagccaagt catatgagac ttggcttcaa ttagaaaaag
     8281 gagagtaatg atgccaattc aaaataaaac catgttgatt acctattctg atagccttgg
     8341 aaataatctt aaagacttat atgataattt ggaagagcat tttggagatg ctattggagg
     8401 agttcacctt ttaccatttt tcccatcaac aggtgatcgt ggatttgcgc cagttgacta
     8461 cgtcgaagtg gactcagctt ttggtgattg ggaggatgtt aagcgtttag gtgagaaata
     8521 ttatcttatg tttgatttta tgattaatca tatttctcgt caatccaagt attataagga
     8581 ctatcaagaa aaacatgaag ccagtgaatt taaagatctc tttttaaact gggataagtt
     8641 ttggccagaa aaccgtccga tacagtctga tgtagattta atttacaagc gtaaggatcg
     8701 tgcaccaaag caagagattg tgtttgaaga tggttcagtg gaacatttgt ggaatacctt
     8761 tggtgaggag cagattgatc ttgatgtgac caaagaagta actatggaat ttatccgtaa
     8821 gaccattcag cacttggcaa gtaatgggtg tgatttgatt cgtctagatg cctttgctta
     8881 tgcagtgaag aaattggata ctaatgattt ctttgtggaa ccagatattt gggatttatt
     8941 ggacaaagtt cgagatatcg ctgctgagta tgggacagag cttttacctg agattcatga
     9001 acactattcg attcagttta aaatagcaga ccatgattac tatgtttatt attttgctct
     9061 tccaatggtg acactttata ctctttacag ttccagaaca gagcgtttgg ctaagtggtt
     9121 aaagatgagc ccgatgaagc aatttacgac gctagatacc catgatggga ttggagtagt
     9181 agatgtcaag gatatcctga ccgatgagga gattgactat gcttcaaatg aactctataa
     9241 ggttggagcc aatgtcaaac gtaagtactc tagtgccgag tataacaact tagatatcta
     9301 ccaaatcaat tcaacctact attcagcgct tggagatgat gatgtcaagt attttctcgc
     9361 tcgtctaatt caagcttttg ccccaggtat tcctcaggtt tactatgtgg gtctattagc
     9421 aggcaagaat gacttgaaat tattagaaga aactaaagaa ggtcgaaata ttaatcgtca
     9481 ttactatagc aacgaggaaa tagcaaaaga agtgcaacga cctgttgtga aggcccttct
     9541 caatctattt tctttccgta accgttcaga agcctttgat ctagaaggga ctactgagat
     9601 agagacacca acagctcaca gcattgtaat caaacgtcaa aataaagata agtccgtaac
     9661 agcagtagca gaaattgatt tgcaaaatca gacttatcgg gtaattgaga atggagttga
     9721 agtaacattt tgaagccttg atatggtgga taaaataggg tttttatttt ggaaaacgtt
     9781 tcctttgttt tcaaattgct aaaaaagtgg tacaatatag gatagcttac tattatctga
     9841 atcagctgat ttggagagaa aggattcatt ttgaaatcaa taggctttat tgaaaagctg
     9901 aaggggttgt ctagtaaaga gctgatttta ttgggaatta tcctgagtat ctttttaccc
     9961 ttttatcttt ttgtagttgt actctgttta tatattatca gtttgatttt tacaggagac
    10021 atgaaaagta ttcttcagaa aatgggggag catccgatgc tgcttctttt tcttagctat
    10081 agtactgtta tatccattct tgcacaaaat tggatgggtc ttgtggcttc agtaggaatg
    10141 tttctattta ctattttctt tttgcactat cagtcgattt tatcccataa attctttcga
    10201 ttgattttgc agttcgtctt gtttggtagt gtcttgtcag ctgcttttgc cagtttagaa
    10261 catttccaaa ttgtgaagaa atttaactat gcttttcttt cacccaatat gcaggtgtgg
    10321 catcagaacc gggcagaagt gaccttcttt aatcctaatt attatggaat tatttgttgt
    10381 ttctgtatta tgattgcttt ctatctgttt acaacgacca agttgaattg gttgaaagta
    10441 ttctgtgtga ttgcaggctt tgttaatctc tttggtttga actttactca aaatcgaact
    10501 gcctttcctg ctattatcgc tggagcaatt atctatctct ttacgactat taaaaactgg
    10561 aaggcctttt ggcttagtat tggggtcttc gcgattggtt tgagtttcct cttttctagt
    10621 gatttgggag ttcgaatggg tactttagac tcttctatgg aagaacgcat ttctatctgg
    10681 gatgctggga tggccttgtt taagcaaaat cctttttggg gtgaagggcc attgacctat
    10741 atgcactctt atcctcggat acatgctcct tatcatgaac atgcccacag tctttatatt
    10801 gatacgattc tgagttacgg aattgtgggt accattttat tagttttgtc ttctgttgct
    10861 cctgttcgct tgatgatgga tatgagtcag gagtcgggga aacgtccgat tatcggcctt
    10921 tatctatctt tccttacagt ggttgctgtg cacggaattt ttgacttggc tctcttctgg
    10981 attcagtcag gctttatttt cttgctagtt atgtgcagta ttccattgga gcatcgaatg
    11041 ttggtatcgg acatgacgga ttaagtttta taagtttgaa atcttctacc ttgggtagga
    11101 gattttttta tacgatgggc atgtcgtgca tctgaggtgt aagtcctctg tagggatcca
    11161 ctaccggtga atacaatagc gctccccaag cctgactatc gtgaggtagc ggattaaaat
    11221 ggtctgggga tagatcgttt taagtctgac gcaggaaata agaattgtca gagaaagcaa
    11281 tagtgaaatt gtaggctatg aatagaaacg tgatagcgag gagcatatag tggataaggt
    11341 agcgagaaat tttaaagtat aaaagatagt cttaatctat atatgtaaat cacaaaagta
    11401 attgaattcg gaataaggtt ggtgtgaaaa gacatagtaa actgaatctt gaatactaga
    11461 atgatacttc tacaatattg ttataattta atttgaattc caaaatcaca ttgttccgtc
    11521 cgtatttcat tttactgtat gtcttcctaa actccaaagt ttctgcgtca aatttcctat
    11581 tttcactgta gtctttgaca cttcgaacga caatttgaat catatattca aaaaaaaatg
    11641 aaaaatttgt gccaacaagc ctaaatattc tgaaaatttg tttgattttt aatggataat
    11701 gtgatataat ggttgtcaat ctataattca cataaacaga ggagtagaaa atgaaaaaaa
    11761 atcgtgtatt tgctacagca ggtcttgttt tattagcagc aggtgtactt gcagcatgca
    11821 gttcttcaaa atcatctgat tcatcagccc ctaaagctta tggctatgtt tatacagcag
    11881 acccagaaac cttggactac ctgatttcaa gtaaaaatag tacaacagta gtgacttcaa
    11941 atgggattga tggtttattc actaacgata attacggtaa tcttgctcct gcagttgcag
    12001 aggattggga agtctctaag gatggtttga cctacactta taagattcgt aaaggggtta
    12061 aatggtttac ctctgatgga gaagaatatg cagaggtgac ggctaaagat ttcgtgaacg
    12121 gtttaaaaca cgcagcagat aaaaaatcag aagctatgta tttagctgaa aattcggtta
    12181 aaggcttggc agattatcta tcaggaactt caacagattt ttcaacagtt ggtgtcaagg
    12241 cggttgatga ttatacgtta caatacactt tgaaccagcc tgaaccgttc tggaactcta
    12301 agttgaccta ttctattttc tggcctctga atgaagaatt cgaaacatca aaaggaagcg
    12361 attttgctaa accaacagat ccgacatcct tgctttataa tggtccattc ttgttgaaag
    12421 ggttgactgc aaaatcttct gtagagtttg taaaaaatga gcaatattgg gataaagaaa
    12481 atgtccacct agatactatc aatctagctt actatgatgg atcagatcag gagtcgctag
    12541 agcgtaactt cactagtgga gcttatagtt atgcccgtct ttaccctacc agctccaact
    12601 attctaaggt tgcagaagaa tacaaggaca atatctatta cacacaatca ggctctggga
    12661 ttgctggtct gggtgtgaat attgatcgcc aaagttacaa ctatacttct aaaactacag
    12721 attcagagaa agtagctact aagaaggcat tgcttaacaa agatttccgt caagccttga
    12781 attttgctct tgatcgctca gcttactcag ctcaaatcaa tggtaaagat ggagcagctt
    12841 tagcagttcg taatttattt gtaaaaccag actttgtttc agctggtgag aagacctttg
    12901 gtgatttagt cgctgctcaa cttcctgctt atggtgatga gtggaaaggt gtgaatttag
    12961 ctgatgggca ggatggttta ttcaatgctg acaaggccaa ggcagagttt gcgaaagcta
    13021 agaaagcttt agaagcagac ggcgttcagt ttcctattca tctggacgtt ccagtagacc
    13081 aagcatcaaa aaactacata tctcgtattc agtcctttaa acaatctgta gaaacagttc
    13141 ttggtgttga aaatgtcgtt gttgatattc aacaaatgac aagtgatgaa ttccttaata
    13201 ttacttacta tgctgccaat gcttcatctg aggattggga tgtatcagga ggagtttcat
    13261 ggggtccaga ctatcaagac ccatctactt acctggatat tttaaaaaca actagcagtg
    13321 aaactacaaa aacatattta ggatttgata atccaaatag cccttcagta gttcaagttg
    13381 gtttgaaaga atacgataaa ttagttgatg aagctgccag agagacaagc gacttgaatg
    13441 tccgttatga aaaatatgca gcggctcaag catggttgac agatagttca ctctttattc
    13501 ctgctatggc ttcttctggt gcagcaccag tgctttcacg aattgttcca tttactggag
    13561 cttctgcgca aacaggctct aaggggtcag atgtttactt caaatatttg aaattacaag
    13621 ataaagtggt gactaaggaa gagtatgaaa aagctcgtga aaaatggttg aaagaaaaag
    13681 ctgaatcaaa tgagaaagct caaaaagaat tggcaagtca tgtgaagtaa ataatttcta
    13741 atagaacttt ctctccatga ggagaaggtt cttttgggat ttttaaagga aataatatga
    13801 aaaaatatat ttttatgcgt gttttgcggt cattggtttc gattttctta gtaacgactt
    13861 tgacctacac gattatctat accttggttc ctcgaaaatt gattttcaag caggatccta
    13921 actataataa aattgcgaca acggctgata aacgtgataa ctatgaaaat actgtgtttg
    13981 agcgtatggg ctacattgag tattacgata ctaaagagtt gcaagaaaag gcaagtagca
    14041 tggattcttc tgtaacagta gaagcaaatg cgaccaataa agctatttat gaaaagtaca
    14101 tcaatcaatt aggtcatggt tggactttgg gagaatttac tgaaagtggt caattctatg
    14161 ctactcgtga aattccaatt tttgaacgtg tttttcactt ctatgctaac ttgattgaca
    14221 ttgaccatac aaataaaatc caagaccctg aaaatccaga cttgaaacgc taccttcgtt
    14281 ttgaaaatga tccagctatc ggatggtcat tggtcggttc aggaactaaa cataaatatc
    14341 tcttgtactt taacagtcag ttcccatttg ttcatcaaaa ctttgtgaac ttgaatttag
    14401 gtgactctta cccaacctat gctaatacac cagttcttca ggttattact caaggtcaag
    14461 gacaaaccaa aactgcccaa gttcagttcc caacaggtaa gaaaacgtct tctgtaaata
    14521 tttactcaag aacctacaag tcacctagtc aggctgactc tcgtgaagta gctagctatg
    14581 ggaaagatga tccttataca gcgactgaaa gtaattacca atatccatct atgattgtca
    14641 gctctgctat tactggtttg attggtttgg ttcttgccta tgctcttgcc gtgccacttg
    14701 gttcagccat ggctcgtttc aagaacactt ggattgatag cctctcaaca gggactttga
    14761 ccttcttgct tgctcttcca acgattgcct tggtttacat cgttcgattg attggatcat
    14821 ctattgccct tccagattca ttccctatct tgggagctgg agattggcgt tcttacgttt
    14881 taccagcagt catccttggt ttgttgggtg ctcctgttac agccatttgg attcgtcgtt
    14941 acatgattga cttgcaatct caagactttg ttcgtttcgc tcgtgcaaaa ggtttgtctg
    15001 aaaaagaaat ttcaaacaaa cacatcttta aaaatgccat ggttccgctg gtttcaggaa
    15061 ttcctggtgc cattattggg gttatcggtg gtgcaaccct tactgaaaca gtcttcgcct
    15121 tcccaggtat gggtaaaatg ttgattgact ctgtaaaagc atctaataac tctatggtcg
    15181 ttggtcttgt cttcatcttt acatgtattt ctatcttctc acgtcttttg ggagatattt
    15241 ggatgactat tattgaccca cgtattaaat tgactgagaa aggaggcaaa taatgtctac
    15301 aatcgataaa gaaaaatttc agtttgtaaa acgtgacgat tttgcctctg aaactattga
    15361 tgcgccagca tattcttact ggaaatcagt gtttaaacaa tttatgaaga aaaaatcaac
    15421 tgtagtcatg ttgggaatct tggtagccat cattttgata agtttcatct acccaatgtt
    15481 ttctaagttt gatttcaatg atgtcagcaa ggtaaacgac tttagtgttc gttatatcaa
    15541 gccaaatgcg gagcattggt tcggtactga cagtaacggt aaatcgctct ttgacggtgt
    15601 ctggttcgga gctcgtaact ccatcctcat ttctgtgatt gcgacagtga ttaacttggt
    15661 tatcggtgtt tttgtcggtg gtatttgggg tatttcaaaa tcagttgacc gtgtcatgat
    15721 ggaagtttac aacgtcatct caaacatccc acctcttttg attgttattg tcttgactta
    15781 ctcaatcgga gctggattct ggaatctgat ttttgccatg agcgtaacaa catggattgg
    15841 tattgccttc atgatccgtg tgcaaatctt gcgctatcgt gacttggaat acaacttggc
    15901 gtcacgtact ttgggaacac caaccttgaa gattgttgcc aaaaatatca tgcctcaatt
    15961 ggtatctgtt attgtgacaa ccatgactca aatgcttcca agctttatct catacgaagc
    16021 cttcttgtct ttcttcggtc ttggattacc gattacagtg cccagtttgg gtcgtttgat
    16081 ttcggattat tcacaaaacg taacaaccaa tgcttacttg ttctggattc cattgacaac
    16141 ccttgtcttg gtatccttgt cccttttcgt agttggtcaa aacttagcgg atgctagtga
    16201 tccacgtaca catagatagg agtagaaatg acaaaagaaa aaaatgtaat tttgactgct
    16261 cgcgatattg tcgtggaatt tgacgttcgt gacaaagtat tgacagccat tcgcggcgtt
    16321 tcccttgaac tagtcgaagg agaagtatta gccttggtag gtgagtcagg atcaggtaaa
    16381 tctgttttga caaagacctt cacaggtatg ctcgaagaaa atggtcgcat tgctcaaggt
    16441 agtattgact accgtggtca ggacttgaca gctttatctt ctcacaagga ttgggaacaa
    16501 attcgtggtg ctaagattgc gactatcttc caggacccaa tgactagttt ggaccccatt
    16561 aaaacaattg gtagtcagat tacagaagtt attgtaaaac accaaggaaa aacagctaaa
    16621 gaagcgaaag aattggccat tgactacatg aataaggttg gcattccaga tgcagataga
    16681 cgttttaatg aatacccatt ccaatattct ggaggaatgc gtcaacgtat cgttattgcg
    16741 attgcccttg cctgccgacc tgatgtcttg atctgtgatg agccaacaac tgccttggat
    16801 gtaactattc aagctcagat tattgatttg ctaaaatctt tacaaaacga gtatcatttc
    16861 acaacaatct ttattaccca cgaccttggt gtggtggcaa gtattgcgga taaggtagcg
    16921 gttatgtatg caggagaaat cgttgagtat ggaacggttg aggaagtctt ctatgaccct
    16981 cgccatccat atacatggag tctcttgtct agcttgcctc agcttgctga tgataaaggg
    17041 gatctttact caatcccagg aacacctccg tcactttata ctgacctgaa aggggatgct
    17101 tttgccttgc gttctgacta cgcaatgcag attgacttcg aacaaaaagc tcctcaattc
    17161 tcagtatcag agacacattg ggctaaaact tggcttcttc atgaggatgc tccaaaagta
    17221 gaaaaaccag ctgtgattgc aaatctccat gataagatct gtgaaaaaat gggatttgcc
    17281 catctggctg actaggagga aggaaatgtc tgaaaaatta gtagaaatca aagatttaga
    17341 aatttccttc ggtgaaggaa gtaagaagtt tgtcgcggtt aaaaatgcta acttctttat
    17401 caacaaggga gaaactttct cgcttgtagg tgagtccggt agtgggaaaa caactattgg
    17461 tcgtgctatc atcggtctaa atgatacaag taatggagat atcatttttg atggtcaaaa
    17521 gattaatggt aagaaatcgc gtgaacaagc tgcggaattg attcgtcgaa tccagatgat
    17581 tttccaagac cctgccgcaa gtttgaatga acgtgcgact gttgattata ttatttctga
    17641 aggtctttac aatcaccgtt tatttaagga tgaagaagaa cgtaaagaga aagttcaaaa
    17701 tattatccgt gaagtaggtc ttcttgctga gcacttgact cgttaccctc atgaattctc
    17761 aggcggtcaa cgtcaacgta tcggtattgc ccgtgccttg gtcatgcaac cagactttgt
    17821 tattgcagat gagccaattt cagccttgga cgtttctgta cgtgcccaag tcttgaactt
    17881 gctcaaaaaa ttccaaaaag agctcggcct gacctatctc ttcatcgccc atgacttgtc
    17941 ggttgttcgc tttatttcag atcgtatcgc agttatttac aagggtgtta ttgtagaggt
    18001 tgcagaaaca gaagaattgt ttaacaatcc aattcaccca tatactcaag ccttgctttc
    18061 agcggtacca atcccagatc caatcttgga acgtaagaag gtcttgaagg tttacgatcc
    18121 aagtcaacac gactatgaga ctgataagcc atctatggta gaaatccgtc caggtcacta
    18181 tgtttgggcg aaccaagccg aattggcacg ttatcaaaaa ggactaaact agtaatggtt
    18241 ttataatttc catgtcaatt tttatggaaa ttaggctctt tgtcaactgt agtgggttga
    18301 agtcagctaa gctcgagaaa ggacaaattt cgtcctttct tttttgatgt tcaaagcgat
    18361 aaaaatccgt tttctgaagt tttcaaagtt tcgaaaacca aaggcattgc gcttgataag
    18421 tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt gaagggcgtt
    18481 gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa gaggatg
//
LOCUS       DAVFJR010000043        18505 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVFJR010000043 DAVFJR010000000
VERSION     DAVFJR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18505
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.044"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..1821
                     /gene="pspC"
                     /locus_tag="VU722_001800"
     CDS             <1..1821
                     /gene="pspC"
                     /locus_tag="VU722_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU1772712.1"
                     /translation="RTLIIKLSAIKTKYLRELNVLEEKSKDELPPKIKEELTAAFEQF
                     KKDTLSTEPEKKVAEAKKKVEEAKKKAEDQKEKDRRNYPTITYKTLELEIAESDVEVK
                     KAELELVKVKANEPRDEEKIKQAEAKVESKQAEATRLKKIKTDREQAEATRLENIKTD
                     REQAEEEAKVKDEPKKRTKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKK
                     VAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAK
                     EPRNEEKVKQAKAEVESKQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQ
                     PAPAPQPEKPAPKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQ
                     QPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGW
                     LQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNANGDMAT
                     GWLQNNGSWYYLNANGSMVTGWLQYNGSWYYLNANGSMATDWVKDGDTWYYLEASGAM
                     KASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(2051..3031)
                     /gene="dusB"
                     /locus_tag="VU722_001801"
     CDS             complement(2051..3031)
                     /gene="dusB"
                     /locus_tag="VU722_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU1772713.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(3018..3890)
                     /gene="hslO"
                     /locus_tag="VU722_001802"
     CDS             complement(3018..3890)
                     /gene="hslO"
                     /locus_tag="VU722_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU1772714.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4055..5482
                     /locus_tag="VU722_001803"
     CDS             4055..5482
                     /locus_tag="VU722_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1772715.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            5641..7149
                     /gene="glpK"
                     /locus_tag="VU722_001804"
     CDS             5641..7149
                     /gene="glpK"
                     /locus_tag="VU722_001804"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU1772716.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPVFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            7191..9017
                     /gene="glpO"
                     /locus_tag="VU722_001805"
     CDS             7191..9017
                     /gene="glpO"
                     /locus_tag="VU722_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU1772717.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFFLRRTNHMLFMRDNLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            9087..9791
                     /locus_tag="VU722_001806"
     CDS             9087..9791
                     /locus_tag="VU722_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU1772718.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            10126..10257
                     /locus_tag="VU722_001807"
     CDS             10126..10257
                     /locus_tag="VU722_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU1772719.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            10278..11828
                     /gene="dltA"
                     /locus_tag="VU722_001808"
     CDS             10278..11828
                     /gene="dltA"
                     /locus_tag="VU722_001808"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU1772720.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQRHTYGDLKADSDS
                     LAAVIDQIGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            11825..13069
                     /gene="dltB"
                     /locus_tag="VU722_001809"
     CDS             11825..13069
                     /gene="dltB"
                     /locus_tag="VU722_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU1772721.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            13083..13322
                     /gene="dltC"
                     /locus_tag="VU722_001810"
     CDS             13083..13322
                     /gene="dltC"
                     /locus_tag="VU722_001810"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU1772722.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            13315..14583
                     /gene="dltD"
                     /locus_tag="VU722_001811"
     CDS             13315..14583
                     /gene="dltD"
                     /locus_tag="VU722_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU1772723.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            14738..15178
                     /gene="adcR"
                     /locus_tag="VU722_001812"
     CDS             14738..15178
                     /gene="adcR"
                     /locus_tag="VU722_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU1772724.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            15178..15882
                     /locus_tag="VU722_001813"
     CDS             15178..15882
                     /locus_tag="VU722_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU1772725.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHNAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            15875..16681
                     /locus_tag="VU722_001814"
     CDS             15875..16681
                     /locus_tag="VU722_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU1772726.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            16691..18196
                     /gene="adcA"
                     /locus_tag="VU722_001815"
     CDS             16691..18196
                     /gene="adcA"
                     /locus_tag="VU722_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU1772727.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
BASE COUNT         5429 a         3644 c         4228 g         5204 t
ORIGIN      
        1 cgcaccttaa tcataaagtt gagcgcaatt aaaacgaagt atttgcgtga attaaatgtt
       61 ttagaagaga agtcgaaaga tgagttgccg ccaaaaataa aagaagagtt aaccgcagct
      121 tttgagcagt ttaaaaaaga tacattatca acagaaccag aaaaaaaggt agcagaagct
      181 aagaagaagg ttgaagaagc taagaaaaaa gccgaggatc aaaaagaaaa agatcgccgt
      241 aactacccaa ccattactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtggaa
      301 gttaaaaaag cggagcttga actagtaaaa gtgaaagcta acgaacctcg agacgaggaa
      361 aaaattaagc aagcagaagc gaaagttgag agtaaacaag ctgaggctac aaggttaaaa
      421 aaaatcaaga cagatcgtga acaagctgag gctacaaggt tagaaaacat caagacagat
      481 cgtgaacaag cagaagaaga agctaaagtt aaagatgaac caaagaagcg gacaaaacga
      541 ggagttcttg gagagccagc aacacctgat aaaaaagaaa atgatgcgaa gtcttcagat
      601 tctagcgtag gtgaagaaac tcttccaagc ccatccctga aaccagaaaa aaaggttgca
      661 gaagctgaga agaaggttga agaagctaag aaaaaagccg aggatcaaaa agaagaagat
      721 cgtcgtaact acccaaccaa tacttacaaa acgcttgaac ttgaaattgc tgagtccgat
      781 gtggaagtta aaaaagcgga gcttgaacta gtaaaagagg aagctaagga acctcgaaac
      841 gaggaaaaag ttaagcaagc aaaagcggaa gttgagagta aacaagctga ggctacaagg
      901 ttagaaaaaa tcaagacaga tcgtaaaaaa gcagaagaag aagctaaacg aaaagcagca
      961 gaagaagata aagttaaaga aaaaccagct gaacaaccac aaccagcgcc ggctcctcaa
     1021 ccagaaaaac cagctccaaa accagaaaaa ccagctccag ctccaaaacc agagaatcca
     1081 gctgaacaac caaaagcaga aaaaccagct gatcaacaag ctgaagaaga ctatgctcgt
     1141 agatcagaag aagaatataa tcgcttgact caacagcaac cgccaaaaac tgaaaaacca
     1201 gcacaaccat ctactccaaa aacaggctgg aaacaagaaa acggtatgtg gtacttctac
     1261 aatactgatg gttcaatggc gacaggatgg ctccaaaaca atggctcatg gtactacctc
     1321 aacagcaatg gcgctatggc gacaggatgg ctccaaaaca atggttcatg gtactatcta
     1381 aacgctaatg gttcaatggc aacaggatgg ctccaaaaca atggttcatg gtactacctc
     1441 aacgctaatg gttcaatggc gacaggatgg ctccaataca atggttcatg gtactacctc
     1501 aacgctaatg gtgatatggc gacaggatgg ctccaaaaca atggctcatg gtactaccta
     1561 aacgctaatg gttcaatggt gacaggatgg ctccaataca atggttcatg gtactaccta
     1621 aacgctaacg gttcaatggc aacagattgg gtgaaagatg gagatacctg gtactatctt
     1681 gaagcatcag gtgctatgaa agcaagccaa tggttcaaag tatcagataa atggtactat
     1741 gtcaatggct caggtgccct tgcagtcaac acaactgtag atagctatag agtcaatgcc
     1801 aatggtgaat gggtaaacta aacctaatat aactagttaa tactgacttc ctgtaagaac
     1861 tctttaaagt attccctaca aataccatat cctttcagta gataatatac ccttgtagga
     1921 agtttagact aaaaaataac tctgtaatct ctagctggat ttatagcgct agagactacg
     1981 gagttttttt gatgaggaaa gaatggcggc attcaagagg ctctttaaga gagttacggg
     2041 ttttaaacta ttaagccttc tccaattgca agagggcttc aatctctgcc agggtgctag
     2101 cttgcgaaat ggctccacgg agtttggcag cgccagatgt tccacggagg tagtgaggag
     2161 cgaggccgcg gaattcacga actgcgacgt tttctccttt gaggttaatc aatcgtttca
     2221 agtgttcgta ggcgatcttc atcttgtctt caaaggtcaa atcaggtagg atttctcctg
     2281 tttcaaagta atggttgatt tggttgaaga ggtaaggatt tcccatggca gctcggccaa
     2341 tcatgactgc gtcagcacca acttcttcga tgcgttgctt ggcttcttgg acagtacgga
     2401 tatcaccgtt ggcgatgaat ggaatcttgg ttagagcttg ggcaaccttg taaagggtct
     2461 caaggtctgc gtggccagta tacatttgtt cacgggtacg gccatgcatg gcgagggcag
     2521 aaacacctgc agcctcagca gcgagagcat tttctactgc cagagatggg tccgcccagc
     2581 cggtacgcat tttgacagta agtgggatat caaggacaga ctggaccttg ttgatgatag
     2641 agtagatctt gtcaggatcc ttgagccaca tagcaccagc ttcgttcttc acgattttgt
     2701 tgacagggca gcccatgttg atatcgacga tatcggtctt ggtgttttct tggatgaatt
     2761 ctgctgcgcg tgctaggctg tcttcatcgc taccaaaaag ttggatagag acagggtttt
     2821 cgccctcatc gatatgaagc atgtgcaggg ttttttcgtt gttgtattgg attcccttgt
     2881 cagagaccat ttccattaca acgagtccag ctccgagctc ttttgcgatg gtacgaaagg
     2941 ctgagttggt cacgccagcc ataggcgcta aaacggtacg attgggaatc tcaacattgc
     3001 caatcataaa aggtgtatta agatttgtca cgaatgagtt cctccaggtc cttttcatca
     3061 aagttgtaag tagtttggca gaattgacaa gtgatttctg ccccgtggtc ttcctctttc
     3121 atttcctgta agtctgagct tggaaggctg gcaagagcgt tcataaagcg ttcatggcta
     3181 cagtcacatt ggaaacggat ttcttcttca gaaagacgct tgtaggcttc gtccccgtag
     3241 atagccttga ggagggcttc gatatggtcg tcgctttcga gaagagtaga gatagctggc
     3301 atttcttgga tgcgtttttc aaagcgagca atctcttctt tcttggctcc tggcaagact
     3361 tgaactagga aaccacctgc aaccttgacc ttgtcttcct cgtccaaaag gacattgagg
     3421 ccgaccgctg aaggcgtttg ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt
     3481 tctccagaga tgaggggagt tatagagttg taaggatttc cagtaccgta gtctgtgata
     3541 acgaggaatt gaccatttcc aacaaaaggt ccgactagga cttcaccagt cgcagtcttt
     3601 ttgatgtcaa caccaggatt ttgaacgtag cctttgacat tccccttggt atcagcgacg
     3661 gtgataatag cacctagaga gctagatccc aacaccttaa ctgtaagttt ggtatttcct
     3721 ttttcattgg ctgcgagaat ctggctggcg ataagagttc gaccaagcgc tacagttgag
     3781 ctagcttggg tttgatgttt ttcttgagca gtgcggacgg tttccgtgct atcaaggaca
     3841 aaagcacgaa aggctccgct ttctgatata gttttaataa ttttatccat agctactatt
     3901 ttagcataaa aatgcccaaa gggggagccg tgtgtttact gattttcagg ataatggacc
     3961 aggaaatcag cataaaaata aaaagagaaa cagattattt cagcatttgt cagatttatg
     4021 ctatgcttaa ggtagaaaat gaaaggggta acaaatgtat ttaggagatt tgatggagaa
     4081 agccgagtgt ggtcaatttt caatcctttc ctttctatta caagagtctc agacgaccgt
     4141 caaggctgta atggaagaaa caggattttc aaaagcaacc ctaaccaaat atgtcaccct
     4201 gctcaatgac aaggctttgg atagtggctt agagctgact attcactcag aagatgaaaa
     4261 tctgcgtctg tctatcggtg cagctaccaa ggggagagat attcggagct tgtttttgga
     4321 gagtgctgtt aaataccaga ttttggttta tcttctctac caccaacagt ttttagccca
     4381 tcagctggct caagaattgg tgattagcga ggctacgctt ggtcgtcact tggctggttt
     4441 aaatcagatt ctgtcagaat ttgatttatc catccaaaat ggacgttggc gaggcccaga
     4501 gcatcagatt cgctatttct atttctgtct tttccgaaag gtttggtcga gtcaggaatg
     4561 ggaaggtcac atgcagaaac cagagagaaa acaggagatt gccaatttag aggaaatctg
     4621 cggtgcaagt ttgtctgcgg ggcagaaatt ggacttggtt ctctgggctc acatcagtca
     4681 acaacgtctt cgggtcaatg cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta
     4741 ttttgacaat atcttctatc ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca
     4801 acatattcca ctaggagttg aggatggtga gatgatgata ttcttctctt ttctcctatc
     4861 tcatcgcatt cttcctcttc atactatgga gtatattctt ggttttggag ggcagttggc
     4921 agatttgctg acgcagttga ttcaagaaat gaagaaggag gaactattgg gggattatac
     4981 agaggaccat gtcacctatg aactcagtca gctttgtgct caagtctatc tctataaggg
     5041 ctatatttta caggatcgct acaagtacca gttagagaat cgtcatccat atttactgat
     5101 ggaacatgat tttaaagaga cagcagagga gatttttcat gctctacctg cttttcaaca
     5161 ggggacggat ttggataaga agattctctg ggaatggctc cagttaatcg aatatatggc
     5221 tgaaaacggt ggccagcata tgcggattgg tctggatttg acatctggtt ttcttgtctt
     5281 ttcaaggatg gcagccattt tgaaacggta tttggaatac aatcgtttta ttaccattga
     5341 agcttatgac cctagtcggc attatgattt gctggttacc aataacccga ttcataagaa
     5401 ggaacagaca ccagtctatt atttaaaaaa tgacttggat atggaggatt tggcagggat
     5461 tcgtcagtta ttattcactt aaaaggcttg gttaatccag cccttttttg tgaaattcac
     5521 acaatctcct cacatttttt ttaaaattaa aaaaagttga taaacaagaa agcgctttat
     5581 tttgtatact agtaagtgta aagaggaaac acctcaagat ctttatcagg aggacagtac
     5641 atgtcacaag aaaaatacat catggccatt gaccagggaa ctacaagttc tcgtgccatc
     5701 attttcaaca aaaaagggga aaaggttagc tcgagtcaaa aagagtttac ccagattttc
     5761 cctcaggcag gttgggttga gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt
     5821 attgcgggtg ctttcatcga aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt
     5881 accaaccaac gtgaaacaac ggttgtctgg gataagaaaa caggacttcc tatctacaat
     5941 gctatcgttt ggcagtcacg ccagacagca cctttggctg agcaactaaa aagccaaggt
     6001 tatgtggaaa aattccatga aaagactggt ttgattattg atgcttactt ctctgctacc
     6061 aaggttcgtt ggattttgga tcatgtagaa ggcgctcaag agcgagcaga aaaaggggaa
     6121 ttgctctttg gtactatcga tacttggttg gtttggaaat tgactgacgg tgcggctcac
     6181 gtgactgact actcaaatgc agctcgtacc atgctttata acattaaaga actcaaatgg
     6241 gatgatgaga ttttggaaat ccttaacatt ccgaaggcta tacttccaga agttcgttct
     6301 aactccgaaa tctacggcaa gacagctcca ttccatttct acggtggaga ggtgccaatc
     6361 tcaggtatgg ctggggacca acaagcagcc ctctttggac agttggcttt tgagccaggt
     6421 atggttaaga atacttatgg aacaggctct ttcatcatca tgaatactgg ggaagagatg
     6481 cagttgtctg aaaacaacct cttgacaacc attggttacg gaatcaacgg taaggtttat
     6541 tatgccttgg aaggttctat cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt
     6601 cttcgcatgg ttgaaaattc accagaatct gaaaaatacg ctcgtgattc tcacaacaac
     6661 gatgaagttt atgtcgttcc agtctttaca ggtctaggcg ctccatactg gaaccaaaat
     6721 gctcgtggtt ccgtctttgg tttgactcgt ggaacaagca aagaagactt tatcaaggcg
     6781 actttgcaat ctattgctta tcaagtgcgt gatatcatcg acactatgca agtggatact
     6841 cagactgcca ttcaagtact gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg
     6901 cagttccagg cggatatttt aggcattgac attgcacgtg ctaaaaactt ggaaacaaca
     6961 gctctaggag cggccttcct agcaggttta tcagtagggt actggaaaga cttggacgag
     7021 ttgaaactct tgaacgagac aggagaactc tttgagccat ctatgaacga atctcgcaag
     7081 gaacaactct acaagggctg gaagaaggct gtgaaagcaa ctcaagtctt tgcggaagta
     7141 gacgactaat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat atggaatttt
     7201 caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg gacctcttga
     7261 ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct agcggtcttg
     7321 agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt tcaacaaaat
     7381 tggttcacgg aggacttcgt tacctcaaac aattcgacgt agaagtggtc tcagatacgg
     7441 tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaatca gatccaatgc
     7501 tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt aaagtagcca
     7561 tggacttgta cgacctcttg gcaggtgtta gcaacacacc agctgcgaac aaggttttga
     7621 gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg
     7681 gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg
     7741 ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc ctctttgacg
     7801 aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa gtgtttgaaa
     7861 tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta cgtaatttgt
     7921 ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac ttggtagtgg
     7981 attcaagtaa aatcaaggtt tcacagccag tttacttcga cacaggtttg ggtgacggtc
     8041 gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact gatacagact
     8101 acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat ctacttggca
     8161 ttgtcaacaa ccgcttccca gaatccaaca tcaccattga tgatatcgaa agcagctggg
     8221 caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt ggaaataacg
     8281 gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct tatctctcca
     8341 aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg
     8401 agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt gatgacaatg
     8461 gtcttttgac tcttgctggc ggtaaaatca cagactaccg taagatggct gaaggagcta
     8521 tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt
     8581 ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat tcagaaatcg
     8641 aagcctttgc gcaacttgga gtatcacgtg gtttggatag caaggaagct cattacctag
     8701 caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc ttggaacaag
     8761 cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc aatgagttga
     8821 ctcttagtcc agttgacttc tttcttcgtc gtaccaatca catgctcttt atgcgtgata
     8881 acttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat gactggacag
     8941 aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac aacgatttag
     9001 cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct tgtcgcccgt
     9061 cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa tttctaggga
     9121 ctttaatcct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca
     9181 agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg
     9241 cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg accatcggtg
     9301 tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg
     9361 caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac tatgaggcag
     9421 aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg
     9481 tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca atctttgctt
     9541 tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact ttgattgtcg
     9601 gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg
     9661 gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt
     9721 acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct
     9781 cacttttcta gtttatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
     9841 tactcaagta cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
     9901 gaaaacaatt attttgatag agcttgagat gaaaatctca ggcttttttc ttttgaaata
     9961 gacatagaaa aaccgcataa tccttaaaat aagctgaaat ctattggaaa catacggtaa
    10021 acaattgaaa agatactata taaagtggta caatggtaga aaaataagct agtaagaatc
    10081 actcttattt tagcgaaaaa ttacagaaat gaatggtttt tcttgatgaa acagagaaaa
    10141 gaattgtacc tctttcttgg tcggacagcc ttgtattttc ttatctttct agggctgctt
    10201 tacttcttta gctatcttgg tcagggtcaa ggaagcttta tctataatga attttaactt
    10261 gaaggagaat ccctattgtg tcaaataaac caatagcaga tatgattgaa accattgagc
    10321 attttgctca gacacagcct agctatcctg tctataatgt tttggggcag agacacactt
    10381 atggcgattt aaaggctgat tcggatagtt tggctgcagt cattgaccaa ataggcttgc
    10441 ctgagaagtc tcctgtggtt gtttttggtg gccaagaata tgaaatgttg gcaacctttg
    10501 tagcgctgac taagtcaggt catgcctaca ttccaattga tagccattcg gccttggagc
    10561 gagtttcagc tattttagaa gtagcagagc caagcttgat tattgccatt tcagcctttc
    10621 ccttggagca ggtttctaca ccaatgataa atctagctca ggttcaagaa gcctttgccc
    10681 aagggaacaa ctatgaaatc acgcatccag tcaagggaga tgataattac tacattatct
    10741 ttacttctgg tacgactggt aagcctaagg gagtgcagat ttcacatgat aatctcctca
    10801 gctttacaaa ctggatgatt acggataagg aatttgcgac accgagtcgt ccgcaaatgc
    10861 tggcacagcc accttattct tttgacttgt ctgtcatgta ttgggcaccg accttggcac
    10921 ttggtggtac gcttttcact cttccttcag tcatcactca ggactttaag caactctttg
    10981 cggctatctt ttcattgcca atcgctatct ggacatcaac accatccttt gcagatatgg
    11041 ccatgttgtc tgaatacttc aacagtgaga aaatgcctgg aatcacgcat ttctactttg
    11101 atggtgaaga attgacggtc aaaacagctc aaaaactgcg cgagcgtttc ccaaatgccc
    11161 gtatcatcaa tgcttacggc ccaacagaag cgacagtagc tctgtcagca gttgccgtga
    11221 cagacgagat gttagcgact ctcaaacgcc taccaatcgg ctataccaag gctgattctc
    11281 caacctttat cattgacgag gaaggaaata aactgccaaa tggcgaacag ggagaaatca
    11341 ttgtttctgg gccagctgtt tcaaaaggtt atatgaacaa tcctgaaaaa acagcagaag
    11401 ccttctttga gtttgaaggt ctgccagcct atcacacagg cgatgtggga accatgacag
    11461 atgagggctt gcttctctac ggcggacgca tggacttcca gattaagttt aacggttacc
    11521 gcattgagtt agaagatgtc tctcaaaacc tcaacaagtc tcgctttatc gaatctgctg
    11581 tcgcagtacc gcgctataac aaggaccaca aggtacaaaa tctattggct tatgtcatct
    11641 taaaagacgg tgttcgtgag cagtttgagc gagatatcga tattaccaag gccatcaagg
    11701 aagacctgac agacatcatg atgtcctata tgatgccatc taaattcctt taccgagaca
    11761 gtttgccact aactccaaat ggaaagattg acatcaaagg attgattaac gaggtgaata
    11821 agagatgatg gagttttttc aacagcttcc tcatttagag ccatatggca atcctcagta
    11881 ttttgtttat gtgattgctg caaccttgcc catctttata ggtctctttt tcaagaaacg
    11941 ctttgcctgg tatgaagtgt tggtaagtct cttctttatt gtcaccatgt tggtgggtgg
    12001 aaagaccaat caactagctg ccttgggtat ttacctttgc tgggaaatat tgctcctgct
    12061 tttctacaag cattatcgaa aaagcaagga tggcaagtgg gtcttctact tagttagttt
    12121 tctgtcccta cttccgatta tctttgtcaa ggtgcaacca gctatcaatg gaacgcagtc
    12181 tttgcttggg ttcttgggaa tttcttacct gacctttcgt tcggttggaa ttgtcatcga
    12241 gctgagagat ggagtgatta aggattttac cctctgggaa ttcctccgtt tccttctctt
    12301 catgccaact ttctcgagtg gtccaatcga tcgctttaag cgatttaatg aaaattatca
    12361 ggctattcct gagcgagatg agttgatgga tatgctggat gaatctgtcc gctatatcat
    12421 gtggggcttt ttgtataagt ttatcctagc tcatgtttta ggagagacct tactacctcc
    12481 tctgaagaat ttagccttgc agtcaggtgg cttctttaat ctctatgcct tggcagttat
    12541 gtatactttt ggtctggagc tcttctttga ctttgcaggt tattctatgt ttgctttggc
    12601 catctcaaac ttgatgggaa tccgtagccc tatcaacttt aacaagccct ttttatcaag
    12661 ggatttaaag gagttttgga atcgctggca tatgagtctg tccttctggt tccgtgactt
    12721 tgtctttatg cgaatggtga tggtgttaac cagaaagaaa gtctttaaaa atcgtaatgt
    12781 aacctcaagc atggcctaca ttgtaaatat gctgattatg ggattttggc atggcgtgac
    12841 ctggtactat atcgcctatg gactctttca tggactaggc ttggtcatca atgatgcctg
    12901 ggttcgcaag aaaaaaacgc tcaataagga acggaaaaaa gcagggaagg ctgccctacc
    12961 tgagaatcgc tggattcagt ttcttggcat ggttgtcact ttccatgttg tcatgttgtc
    13021 attcttaatc ttttctggat tcttgaataa tctatggttt aaaaaataaa aggaaataaa
    13081 atatggatat caaatcagaa gttattgaaa ttattgatga gttgtttatg gaagatgttt
    13141 ctgacatgat ggatgaagat ctttttgatg caggtgtctt ggatagtatg ggaacggttg
    13201 agttgattgt ggagattgag aaccgttttg acattcgtgt ccctgtaaca gagtttggtc
    13261 gtgacgactg gaatacagct aataaaatca tagctggtat tgtggagcta caaaatgctt
    13321 aaacgcttat ggatgatctt cggaccggtc ttgatcgctg gtttgttggt ttttctgctc
    13381 attttctttt atcctactga gatgcatcat aatctaggag ctgaaaagcg ttcagcagtg
    13441 gctactacta tcgatagttt taaggagcga agtcaaaaag tcagagcact atctgatcca
    13501 aatgtgcgtt ttgttccctt ctttggctct agtgaatggc ttcgttttga cggtgctcat
    13561 cctgcggtat tagctgagaa atacaatcgt tcctaccgtc cttatctttt aggacagggg
    13621 ggagctgcat cgcttaacca atattttgga atgcaacaga tgttaccaca gctggagaat
    13681 aaacaagttg tgtatgttat ctcacctcag tggttcagta aaaatggcta tgatccagca
    13741 gccttccagc agtattttaa tggagaccag ttgactagtt ttctgaaaca tcaatctggg
    13801 gatcaggcta gtcaatatgc agcgactcgc ttactgcaac agttcccaaa cgtagctatg
    13861 aaggacctgg ttcagaagtt ggcaagtaaa gaagaattgt cgacagcaga caatgaaatg
    13921 attgaattat tggctcgttt taatgaacgc caagcctcct tttttggtca gttttcggtt
    13981 agaggctatg ttaactacga taagcatgta gctaagtatt taaaaatctt gccagaccag
    14041 ttttcttatc aagcaataga agatgttgtc aaagcagatg ctgaaaaaaa tacttccaat
    14101 aatgagatgg gaatggaaaa ttatttctat aatgagcaga tcaagaagga tttgaagaaa
    14161 ttaaaggatt ctcagaaaag ctttacctat ctcaagtcgc cagagtataa tgacttgcag
    14221 ttggttttaa cacagttttc taaatctaag gtaaacccga tttttatcat tccacctgtt
    14281 aataaaaaat ggatggacta tgctggtcta cgagaggata tgtaccaaca aacggtgcag
    14341 aagattcgct accagttaga aagtcaaggt tttaccaata tagcagattt ttctaaggac
    14401 ggcggggagc ctttctttat gaaggacacc attcaccttg gttggttggg ttggttggct
    14461 tttgacaagg cagttgatcc tttcctatcc aatcccacac cagctccgac ttaccatctg
    14521 aatgagcgct ttttcagcaa agattgggcg acttatgatg gagatgtcaa agaatttcaa
    14581 tagataatat aatatagaag agttcaagaa tgaaactagt tttcacgttt tttcttgact
    14641 ctttttttgc ttgtgatata attaactggt aaacaaaatg tcaaagaata gtatttttct
    14701 cttaaaaaag agaagtctaa aaggaaagga gtcagatatg agacagctag caaaggatat
    14761 caatgctttt ttgaatgagg tgattttgca ggcggaaaat cagcatgaaa tcctaatagg
    14821 tcattgcact agcgaggtgg ccctgaccaa tactcaggag catatcctta tgctcttgtc
    14881 agaggaatct ttaacaaatt cagaattggc ccgtcgtctc aatgtcagtc aggcggcagt
    14941 taccaaggcc attaagtctt tggtcaagga agggatgttg gaaacatcta aagattctaa
    15001 agatgcgcgt gtgatttttt atcagttgac tgacttggct cgtccaatcg ctgaggagca
    15061 ccaccatcac catgagcata cacttttaac ctatgaacaa gtggcgactc agtttactcc
    15121 aaatgaacaa aaagtgattc agcggttttt gactgcttta gtaggagaaa tcaaataatg
    15181 agatatatta cggtagagga tttgtccttc tattatgata aggagcctgt tcttgaacat
    15241 atcaattata gtgttgatag tggggaattt gttaccttga ctggggaaaa tggagcggct
    15301 aagacgacgc tcatcaaggc tagtcttgga attctgcaac cacgcattgg aaaggtggct
    15361 atttcaaaga caaatacgca aggtaagaaa ttgagaatag cctatcttcc tcaacaaatt
    15421 gccagtttta atgctggttt tccaagtacg gtctatgaat ttgtcaagtc gggtcgctat
    15481 ccgagaaaag gctggttccg tcgtttgaat gctcatgatg aggagcatat caaggccagt
    15541 ctggactcag ttggcatgtg ggaacatcga gacaaacgct tggggtctct atctggggga
    15601 caaaagcagc gagcggtgat tgcgcgtatg tttgcttctg accctgatgt gtttatccta
    15661 gacgagccga caacggggat ggatgcagga agtaaaaatg aattttacga actcatgcac
    15721 cacaacgccc atcatcatgg caaggctgtt ttgatgatta cccatgaccc tgaagaagtt
    15781 aaggattatg cggatcgcaa tattcatcta gtccgtaacc aagactcgcc atggcgttgt
    15841 ttcaatgttc atgagaatgg ccaggaggtg ggccatgctt agtttattat cttacgactt
    15901 tatacaacgc gcctttttgg cggttattgc tatgagtctt ttctcaccgg tattgggaac
    15961 cttcctcatc ttgcgtcgtc agagtttgat gagtgatacc cttagccacg tctcactttc
    16021 aggtgtagcc tttggtctgg ttttggggat ttctccaact gtttctacta ttgccattgt
    16081 cttgattgcg gcggtctttc tggagtatct ccgtacggtt tacaagagct ttatggaaat
    16141 cgggacagct atcctcatgt caacaggtct ggctgtttct ctgattgtca tgagcaaggg
    16201 taaaagctcg agttcaatga gtttggacca atatctcttt ggttcgatcg tgactatcag
    16261 tgaagaacag gtcatttccc tctttgtcat tgcggcggtt gttttgattt tgacctttct
    16321 ctttcttcgt cctatgtata tcttaacttt tgacgaagat acggcctttg tggatggctt
    16381 gccagttcgt accatgtcca ttctttttaa catggtgaca ggggtggcta ttgcccttat
    16441 gattcctgca gcaggagctc ttctggtatc gaccattatg gtcttgccag ctagtattgc
    16501 cctgcgtctg gggaaaaact ttaaatcggt tatgctgctt gccagtgcga ttggcttttt
    16561 gggaatggta gcaggacttt acatttccta ctatgcagaa acacctgcaa gtgcaagtat
    16621 taccattatt tttgtaactg tctttatact aatcagttta gtaagacgtt ttatcaaata
    16681 ggagacgaac gtgaaaaaaa ttagcttatt actagccagt ctatgtgcct tgtttttagt
    16741 ggcttgttcc aatcaaaaac aggcagatgg taaactcaat atcgtgacaa ccttttaccc
    16801 tgtctatgaa tttaccaagc aagtcgcagg agatacggct aatgtagaac tcctaatcgg
    16861 tgctgggaca gaacctcatg aatacgaacc atctgccaag gcagttgcca aaatccaaga
    16921 tgcagatacc ttcgtttatg aaaatgaaaa catggaaaca tgggtaccta aattgctaga
    16981 taccttggat aagaaaaaag tgaaaaccat caaggcgaca ggcgatatgt tgctcttgcc
    17041 aggtggcgag gaagaagagg gagaccatga ccatggagaa gaaggtcatc accatgagtt
    17101 tgacccccat gtttggttat caccagttcg tgccattaaa ctagtagagc acatccgcga
    17161 cagcttgtca gcagattatc ctgataaaaa agagaccttt gagaagaatg cagctgccta
    17221 tatcgaaaaa ttgcaagcct tggataaggc ttacgcagaa ggcttgtctc aagcaaaaca
    17281 aaagagcttt gtgactcaac acgcagcctt taactatctt gccttggact atggactcaa
    17341 acaagtcgca atctcaggac tttctccaga tgcagagcca tcagctgctc gcttggcaga
    17401 attgacagag tatgtcaaga aaaataaaat cgcctatatc tattttgaag aaaatgcctc
    17461 acaagccctt gctaacacac tttcaaaaga agcaggtgtc aaaactgatg tcctcaatcc
    17521 tttagaaagt ctgacagaag aggacaccaa ggctggagaa aactacattt ccgtgatgga
    17581 gaaaaacctc aaggctttga aacaaacaac agaccaagaa ggcccagcaa tcgaacctga
    17641 aaaggcagag gataccaaga cagtccaaaa tggttacttc gaggatgcag ctgtcaagga
    17701 ccgcaccttg agtgactatg caggtaactg gcaatcagtt tatcctttcc ttgaagacgg
    17761 cacgtttgac caagtctttg actacaaggc taagttgact ggtaagatga cccaggctga
    17821 gtacaaggct tactatacaa aaggctatca gacagatgtg actaagatta acattactga
    17881 taatactatg gaatttgttc aaggtggaca aagcaagaaa tacacttaca agtatgtcgg
    17941 taagaaaatt ttgacttaca agaaaggcaa tcgtggcgtg cgtttcctct ttgaagccac
    18001 agatgctgac gctggacaat tcaagtatgt tcagtttagt gaccacaatg ttgccccagt
    18061 taaggcagaa catttccata tcttttttgg aggtacaagc caagaagctc tatttgaaga
    18121 aatggataat tggccaacct actacccaga taacctatct ggccaagaaa tcgcccaaga
    18181 aatgttggcg cattgatgag aaatcgacta gttcataaga gctagtcggt tttttgatac
    18241 tagatggcta acttcattat agacctttca gaactaaggg aacctgaaaa aataaataaa
    18301 actcttgaaa tatctggact tatatgctag aatgtagtta gtgtataagg ttcattagaa
    18361 caccaaagcc cctaactagt gccatagtta agggcttttt tgacgtatct tagcgattta
    18421 atgggtgttt ataggctagt cagtcggtct acttcttacc atctagccat ttgcagacga
    18481 aatacaagat aattcctgcg atgac
//
LOCUS       DAVFJR010000044        18104 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVFJR010000044 DAVFJR010000000
VERSION     DAVFJR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.045"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            1156..2415
                     /locus_tag="VU722_001816"
     CDS             1156..2415
                     /locus_tag="VU722_001816"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU1772728.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2431..2982
                     /locus_tag="VU722_001817"
     CDS             2431..2982
                     /locus_tag="VU722_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772729.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICNQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2975..4252
                     /locus_tag="VU722_001818"
     CDS             2975..4252
                     /locus_tag="VU722_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1772730.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4268..5128
                     /locus_tag="VU722_001819"
     CDS             4268..5128
                     /locus_tag="VU722_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU1772731.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNISKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5353..5463
                     /locus_tag="VU722_001820"
                     /pseudo
     CDS             5353..5463
                     /locus_tag="VU722_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            5509..6313
                     /locus_tag="VU722_001821"
                     /pseudo
     CDS             5509..6313
                     /locus_tag="VU722_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6505..8796
                     /gene="pcrA"
                     /locus_tag="VU722_001822"
     CDS             6505..8796
                     /gene="pcrA"
                     /locus_tag="VU722_001822"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU1772732.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNIWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFFHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANMQDMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8839..9519
                     /gene="radC"
                     /locus_tag="VU722_001823"
     CDS             8839..9519
                     /gene="radC"
                     /locus_tag="VU722_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU1772733.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9516..10205)
                     /locus_tag="VU722_001824"
     CDS             complement(9516..10205)
                     /locus_tag="VU722_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU1772734.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGGQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDNVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10223..10864)
                     /locus_tag="VU722_001825"
     CDS             complement(10223..10864)
                     /locus_tag="VU722_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU1772735.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10947..11153)
                     /locus_tag="VU722_001826"
     CDS             complement(10947..11153)
                     /locus_tag="VU722_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU1772736.1"
                     /translation="MFELTYKDCYHVERTLKYEALMLTLSGCVTLPDTLYVTSLTFRG
                     QKVYQGLVEDLYRFLSHADFLHQN"
     gene            complement(11161..11508)
                     /locus_tag="VU722_001827"
     CDS             complement(11161..11508)
                     /locus_tag="VU722_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU1772737.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11513..12628)
                     /locus_tag="VU722_001828"
     CDS             complement(11513..12628)
                     /locus_tag="VU722_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1772738.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQENHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGIVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12638..13597)
                     /locus_tag="VU722_001829"
     CDS             complement(12638..13597)
                     /locus_tag="VU722_001829"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU1772739.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13710..14279)
                     /locus_tag="VU722_001830"
     CDS             complement(13710..14279)
                     /locus_tag="VU722_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU1772740.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14407..15078
                     /locus_tag="VU722_001831"
     CDS             14407..15078
                     /locus_tag="VU722_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU1772741.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15062..15880
                     /locus_tag="VU722_001832"
     CDS             15062..15880
                     /locus_tag="VU722_001832"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU1772742.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINCVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15877..16773
                     /locus_tag="VU722_001833"
     CDS             15877..16773
                     /locus_tag="VU722_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1772743.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16817..17791
                     /gene="pta"
                     /locus_tag="VU722_001834"
     CDS             16817..17791
                     /gene="pta"
                     /locus_tag="VU722_001834"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU1772744.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         5386 a         3296 c         3950 g         5472 t
ORIGIN      
        1 atttacccac tacaaatatt atagagccaa aaatcccgtg cctcatcaga cacgggattt
       61 tgtggtacga cgggcatgta tagcgaactg aatctggaat agcacagcat atcttctaaa
      121 atatagtaaa atgaaatgag aacaggacaa atcgatttct aacaatgttt tagaagtaga
      181 ggtgtactat tctagtttca atcaactata ttgttataaa ttgatttgaa tttcaaaatt
      241 aaattgtttg attcttattt caatttgtta tagtatatct gatgtcaaag ttctcggcga
      301 gtcaaatagc gattcccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga
      361 tagaccgttt taagtctgac gctggaaata agaattgtca gaagaaggga tagagaaatc
      421 gtggctctac gaacaggaac gtgataataa ggcgtatata gcggataaga gggcctcaaa
      481 ctctaaagtc caaaaaggta gtcgtaacct atatgcgtaa atcacgagag taattgaatt
      541 cgtactaaga ttttctattt tcactgtaac cttttaacgt ccttatatct tgtatacacg
      601 aggaaagatg tacgacttat cccgtgaggt ctatcactat aaagagaaaa cgacagatag
      661 aagtgatcct gagtcacggt tatctttaaa atagattgtc tgataggacg gtatgtataa
      721 aacgcttctg tgaactgaga gaaggggaga agttcttgct aaaatttagt tgaacagccg
      781 tattccgata cttagataag agatctagtc ttagccccta ctcagtttta ggggataaaa
      841 aaggggcaat agcgattcga gaaagattat actcttcgaa aatctcttca aatcacgtca
      901 atatcgcctt gccgtatgtg taggatactg actacgtcag ttccatctac aacctcaaaa
      961 cagtgttttg agcaacctgc ggttagtttc ctagtttgat ctttgatttt cattgagtat
     1021 tagtaattca gttactaact cgtcaactct gatttatcca ataaaattga aaaggatgga
     1081 aaaaaggata aatttatgat atactttatt ttgaagacct tattagaaat cttgaaagag
     1141 tattgaaaac ttagaatgag aaaaattgtt atcaatggtg gattaccact gcaaggtgaa
     1201 atcactatta gtggtgctaa aaatagtgtc gttgccttaa ttccagctat tatcttggct
     1261 gatgatgtgg tgactttgga ttgcgttcca gatatttcgg atgtagccag tcttgtcgaa
     1321 atcatggaat tgatgggagc tactgttaag cgttatgacg atgtattgga gattgaccca
     1381 agaggtgttc aaaatattcc aatgccttat ggtaaaatta acagtcttcg tgcatcttac
     1441 tatttttatg ggagcctctt aggccgtttt ggtgaagcga cagttggtct accgggagga
     1501 tgtgatcttg gtcctcgtcc gattgactta caccttaagg cgtttgaagc tatgggtgcc
     1561 actgctagct acgagggaga taacatgaag ttatctgcta aagatacagg acttcatggt
     1621 gcaagtattt acatggatac ggttagtgtg ggagcaacga ttaatacgat gattgctgcg
     1681 gttaaagcaa atggtcgtac tattattgaa aatgcagccc gtgaacctga gattattgat
     1741 gtagctactc tcttgaataa tatgggtgcc catatccgtg gggcaggaac taatatcatc
     1801 attattgatg gtgttgaaag attacatggg acacgtcatc aggtgattcc agaccgcatt
     1861 gaagctggaa catatatatc tttagctgct gcagttggta aaggaattcg tataaataat
     1921 gttctttacg aacacctgga agggtttatt gctaagttgg aagaaatggg agtgagaatg
     1981 actgtatctg aagacagcat ttttgtcgag gaacagtcta atttgaaagc aatcaatatt
     2041 aagacagctc cttacccagg ctttgcaact gatttgcaac aaccgcttac ccctctttta
     2101 ctaagagcga atggtcgtgg tacaattgtc gatacgattt acgaaaaacg tgtaaatcat
     2161 gtttttgaac tagcaaagat ggatgcggat atttcgacaa caaatggtca tattttgtac
     2221 acgggtggac gtgatttacg tggggccagt gttaaagcga ccgacttaag agctggggct
     2281 gcactagtca ttgctgggct tatggctgaa ggtaaaactg aaattaccaa tatcgagttt
     2341 atcttacgtg gttattctga tattatcgaa aaattacgta atttaggagc ggatattaga
     2401 cttgttgagg attaaaccgt agaggtgttt atgaatattt ggaccaaatt agcaatgttt
     2461 tctttttttg aaacggatcg cttgtatttg cgtcctttct tttttagtga tagtcaggac
     2521 ttccgcgaga tagcttcaaa tccagaaaat cttcaattta ttttcccaac gcaggcaagt
     2581 ctggaagaaa gtcaatatgc actggccaat tactttatga agtccccttt gggagtgtgg
     2641 gcaatttgta accagaaaaa tcaacaaatg attggttcta ttaaatttga gaagttagat
     2701 gaaatcaaaa aagaagctga gcttggctat tttttgagaa aagatgcttg gtcgcaagga
     2761 tttatgacag aggttgttag aaaaatttgt cagctttctt ttgaggaatt tggcttaaaa
     2821 caattatcta tcattaccca ccttgaaaat gaagctagcc aaagagttgc tcttaagtct
     2881 ggatttagtt tgttccgtca gtttaaggga agtgatcgtt acacaagaaa aatgcgggat
     2941 tatcttgaat ttcggtatgt aaaaggagag ttcaatgagt aagcatcagg aaattctaag
     3001 ctatttggag gaattaccag taggtaaaag ggtcagtgtt cgtagcattt cgaatcatct
     3061 aggagttagt gatggaacag cctatcgggc tattaaagaa gctgaaaacc gtggaattgt
     3121 ggagacccgt cctagaagtg gaacaattcg tgttaaatcc cagaaagttg ctatagagag
     3181 attaacgttt gctgaaattg cagaagtgac ttcttctgag gttctggctg ggcaagaagg
     3241 tttagagaga gaatttagta agttttcaat tggtgccatg actgaacaaa atatcttgtc
     3301 ttaccttcat gatggggggc tcttgattgt cggagaccga acccgtattc agttgctagc
     3361 cttggaaaat gaaaatgcag ttctggttac agggggattt caggttcatg atgatgtgct
     3421 taaactggcc aatcaaaaag ggattcctgt tctaagaagt aagcatgata cctttaccgt
     3481 cgcgaccatg atcaataaag ccttgtcaaa tgtccaaatc aagactgata ttctgacagt
     3541 tgagaaactt tatcgcccta gtcatgagta tggttttctg agagagacag atacagttaa
     3601 agattatttg gacttggttc gtaagaatcg tagcagccgt ttccctgtta tcaatcaaca
     3661 tcaggtcgtt gttggcgttg taaccatgag agacgctggt gataaatcac caagcacgac
     3721 aattgataag gttatgtctc gtagtctatt tttggttgga ttatcgacaa atattgccaa
     3781 tgtgagtcaa cggatgatcg cagaagactt tgaaatggta ccagttgttc gaagcaatca
     3841 aactttgctt ggcgttgtga cgcggcgaga tgtcatggag aagatgagtc gttcccaagt
     3901 ttcggctcta ccaacttttt ctgagcagat tggacaaaag ctctcttatc accatgatga
     3961 agtagtcatt acagtggaac cctttatgct agaaaaaaat ggagttttgg ctaatggtgt
     4021 attggcagaa attctgaccc acatgaccca agatttagtt gttaatagtg gtcgcaatct
     4081 cattatcgag cagatgctga tctacttttt gcaggctgtt cagatagatg atatattgcg
     4141 cattcaggca cggattattc atcatacgag acggtcagct ataattgatt acgatattta
     4201 tcatggtcac cagattgttt caaaagcaaa tgtgactgtt aaaattaatt agaaactagg
     4261 agaaaagatg ataacattaa aatcagctcg tgaaatcgaa gctatggaca aggctggtga
     4321 ttttctagca agtattcata taggcttacg tgatttgatt aagccaggcg tagatatgtg
     4381 ggaagttgaa gaatatgtcc gccgtcgttg taaagaagaa aatttccttc cacttcagat
     4441 tggggttgac ggtgccatga tggactatcc ttatgctacc tgttgctctc ttaacgatga
     4501 agtggctcac gctttccctc gtcattatat cttgaaagat ggtgatttgc tcaaagttga
     4561 tatggttttg ggaggtccca ttgctaaatc tgacctgaat atctcaaaat taaacttcaa
     4621 caatgttgaa caaatgaaaa aatatactca gagctattct ggtggtttag cagactcatg
     4681 ttgggcttat gctgttggta caccgtccga agaagtcaaa aatttgatgg atgtaaccaa
     4741 agaagctatg tacaagggta ttgagcaagc tgttgttgga aatcgtatcg gtgatatcgg
     4801 tgcggctatt caagaatacg ctgaaagtcg tggttacggt gtagtgcgtg atttggttgg
     4861 tcatggtgtt ggcccaacta tgcacgaaga accaatggtt cctaactatg gtattgcagg
     4921 tcgtggactc cgtcttcgtg aaggaatggt cttaaccatt gaaccaatga tcaatacagg
     4981 cgattgggaa attgatacag atatgaaaac tggttgggcg cataagacca ttgacggtgg
     5041 attgtcatgt cagtatgaac accaatttgt cattacgaaa gatggacctg ttatcttgac
     5101 tagccaaggt gaagaaggaa cttattaata aaaagtgaaa agactactgg aagtttattt
     5161 tgataaaaaa tccagtagat cttttcataa taaaacgcat tgtatcaagt gttaggggct
     5221 gatatcatgc gtttttctgc ttttaagatt ttttccaact ctgtttgtaa gcgcatcata
     5281 acaaagggtc taggattcag ggctctcctc ctatatacta ttagtaaagt aaaactaagg
     5341 gaggatattt tagtgtcgca gtctattgtt cctgtagaga ttccacaata ttgtcgtttt
     5401 gattctaaaa agagaaatgg aattctgttt aatgttcgta ttgccaatct taaatttacc
     5461 ttttttagat tagacttcct gcgaaacaaa atatggtata gtagttctat gaattatgaa
     5521 gcaagtaaac aactaactga tgcacgattt aaatgtcttg ttggtgttca gcgcacgact
     5581 tttgaagaga tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga
     5641 cgaaaaccta aattaagcct agaagacttt cttatggcca ctcttcaata tgtgcgagaa
     5701 taccgcactt atgaacaaat tgcggctgat tttggtattc acgaaagcaa cttaatccgt
     5761 cggagctaat gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct
     5821 ctcagttctg aggatacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa
     5881 aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat
     5941 tgtcacaagt caagggagaa ttgtttcttt ggatatcgct gtgaactatt gtcatgatat
     6001 gaagttgttc aaaatgagtc gcagaaatat cggataagct ggaaaaatct tggctgacag
     6061 tggttatcaa gggcccatga agatatatcc tcaagcacaa actccacgta aatccagcaa
     6121 actcaagccg ctaacagttg aagataaagc ttataaccat gcgctatcca aggagagaag
     6181 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacttatcg
     6241 aaatcatcgt aaacgcttcg gattacaaat gaatttgatt gctggtatta tcaatcatga
     6301 actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt
     6361 gggtgaaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt caatccacta
     6421 tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa tagaaatatt
     6481 gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa tgaccgtcag
     6541 gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggggc tggttctgga
     6601 aagactcgtg ttttaaccca ccgtatcgct tatttgattg atgaaaagct ggtcaatcct
     6661 tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa agagcgtgct
     6721 tatagcctca atccagcgac tcaggactgt ctgattgcga ccttccactc catgtgtgtg
     6781 cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac aattgtggat
     6841 cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt ggatcctaaa
     6901 aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga tttgattgat
     6961 gatgttgctt atgctgccca agctggcgat atgtatacgc aaattgtggc ccagtgttat
     7021 acagcctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga tttgattatg
     7081 ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca gcaaaaattc
     7141 caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca attggtcaaa
     7201 ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcagacca gtctatctac
     7261 ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta ccccaaagcc
     7321 aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca agcggccaac
     7381 gaggttatta aaaacaataa aaatcgccgt cctaaaaata tctggactca aaacgctgat
     7441 ggggagcaaa tcgtttacta tcgtgccgat gatgagctgg atgaggctgt atttgtagcc
     7501 agaaccatcg atgaacttag tcgcagtcaa aacttctttc ataaggattt tgcagttctc
     7561 tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc taacattcct
     7621 tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga tattattgct
     7681 tatctcaacc ttattgctaa tttgagtgac aatattagtt ttgagcgtat tatcaacgag
     7741 cctaaacgag gaattggtcc aggtacagtt gagaaaatcc gtgattttgc gaatatgcaa
     7801 gacatgtcca tgctagatgc ttctgctaat attatgttgt ctggtatcaa gggtaaggca
     7861 gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca gctagaccac
     7921 ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt cgatattctt
     7981 aacgcccaag cgactctaga aagcaaggca cgggttgaaa atatcgaaga gtttctttct
     8041 gttacgaaga actttgatga caccactgat gtgacagaag aggaaactgg tctggacaaa
     8101 ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg tagtcaggag
     8161 acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt tccagttgtc
     8221 tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga agatccagat
     8281 gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga gaaaattctc
     8341 tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa ccgtccgact
     8401 cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc tcgtcctgca
     8461 aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca aggtatgagt
     8521 ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcaat ccagtcaagc
     8581 ggtcttccat ttggtcaatt tacagctggc gcaaaaccag catctagcga ggcaaattgg
     8641 tccattggtg atattgctct ccacaagaaa tggggagagg gaaccgttct ggaagtttca
     8701 ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt gaaaaaactt
     8761 ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct cacgaataat
     8821 aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact attaccaaga
     8881 gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct agctatttta
     8941 ctcaggacag gaacacgtca agttagcgtt tttgaaattg cccaaaaagt cttgaacaat
     9001 ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag tttgtctggt
     9061 attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca tcgtattcac
     9121 aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc caagaagatg
     9181 cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct caatactcaa
     9241 aatcaaatca tccatcagca gaccattttt atcggttctg taactcgtag tatcgctgaa
     9301 ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat cttggtccac
     9361 aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac taaacttgtt
     9421 aaagaagcct gcgaactgat ggggattgtt ctcttggacc atttgattgt ctctcattct
     9481 aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac gacatagtca
     9541 aagagtttct tatctttggg acgattttca aaaagaagtt ctggatgcca ttggacaccg
     9601 agaaaggcga cattatccgt actcatgaca gcctcaatga taccatcttt aggatcatga
     9661 gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa ggagttgata
     9721 tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac caagcgttga
     9781 gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta caaagttcca
     9841 cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg ctttttctgt
     9901 ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtg atagtcatcg
     9961 ctatcaatgg ttttgggttc gccatagaat tttggatcga cattttgtcc acctgtcaag
    10021 atgagcttgt caatcaaact gatatagtgg caggccattt cttgaccacc aatcggtagg
    10081 atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc tgcgtagctc
    10141 atcatgatgt catcatctgg atgagctttt tcgtttcctg taatcccaat aactggtttt
    10201 ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg agggtttgga
    10261 gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc agatggactg
    10321 gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca acttcttgtg
    10381 acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg attttatcct
    10441 tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg acttcaggat
    10501 ggtcatctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg aagcggtagt
    10561 ggagaagggc atggcccata tttccaatac caaccagcat gacattggtg atggagttat
    10621 cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca aaaccacgcc
    10681 gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca atcccaatgg
    10741 cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat ctcttaaaaa
    10801 ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagcaaac tgtttatctt
    10861 tcacaaaatc acaacctttc tattcttcta ttttatagaa atattgtgaa aaaatcaaca
    10921 aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc atgagataga
    10981 aaacggtaga ggtcttcgac cagaccctga taaactttct gacccctaaa agtcagagaa
    11041 gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat gagagcctca
    11101 tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa cattttggct
    11161 ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga ggaagtagaa
    11221 tttttcctga tgaatgtggt ggtcttctga tttgaaaata tcaactagac gaaggccaaa
    11281 cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga ttttgagttg
    11341 gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat agttaccaac
    11401 cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag ggctaagagt
    11461 gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat ggctaacctc
    11521 cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta ttttgtggcg
    11581 acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac atggcttcaa
    11641 gaacatggct ggattggaca atgcctgcag tacaggctga gccagtagag attgaaattc
    11701 cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat ccaatattga
    11761 gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaattccc tccagctctg
    11821 ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt ttttctaggt
    11881 cttcttttag ggctgcaacc atgcctacaa tggcaggcag attttcagtt cctgcacgtt
    11941 ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta gatgcgtaga
    12001 gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga aaatcaatgc
    12061 ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca acatgatagg
    12121 cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg tttcctgtct
    12181 cattattggc aaacatggtg gaaaccaaaa tcgtatcgtc acgtaaagcc ttttgaattt
    12241 gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac ccaaagtgtt
    12301 gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt gtgatgatat
    12361 gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta ttgccttcag
    12421 tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg gctagttcct
    12481 gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata ctagaaggat
    12541 ttccgtggtt ttcttgcata accttggtca tagctgaaat agcaactgct gacataggag
    12601 tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta ttgtaggcaa
    12661 agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca attaactcac
    12721 tagcagtgat atagcataca tttttaggag ttttttcttt tgttgctact gaatcagtca
    12781 caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg acgaagagac
    12841 cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt ttagaagctt
    12901 cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc ttaccttcaa
    12961 catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag tcgataatgg
    13021 cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct gaatttttag
    13081 ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt tttgcgaata
    13141 ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc tgaacggcat
    13201 gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg gcaactagtt
    13261 ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag ccaaaatatg
    13321 gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc atgattaaca
    13381 attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa acatcataac
    13441 cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga cgtgatgata
    13501 gttttccaag tgggacacca acagcttggg caattttttg tgcaatctct tggttagagt
    13561 tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct ctgtaaactt
    13621 tataaatcct agttatattt accttacata tatgaactgg gatttgtgta tttttatctt
    13681 ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt gacaaatcga
    13741 accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa ttgtcggaaa
    13801 tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc tgtcatatca
    13861 aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc atagcgaagc
    13921 gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt cgccaattca
    13981 tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc atcttttagt
    14041 tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag tgtcaactca
    14101 gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag ttcaaaatca
    14161 ggcgtgtcta tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa ctggtctttt
    14221 agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa atgtttcatt
    14281 tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat tgtatttatt
    14341 gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga gaacaaggga
    14401 gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc tgttggtgag
    14461 ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa gcattctcca
    14521 attgagtttg tgaccggtcg agttaagcca attgagagca tcaaagaaaa aatggctcgt
    14581 cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg cttacgtgtg
    14641 atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa gcgtcaggat
    14701 atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg ctatcgttcc
    14761 tatcatgtgg tagtagaata tacggttgat accatcaatg gagttaagac tattttggca
    14821 gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca ttctctcaac
    14881 tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat tacagctaga
    14941 atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca agaagcccag
    15001 gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag tgacgataca
    15061 gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc agagtcaaag
    15121 ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca atgataccaa
    15181 tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct ttcataagta
    15241 cgaaaatcag cttgacaagg tccgctttat cggtcttcat actggacatt tgggcttcta
    15301 tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc tagatactgg
    15361 ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt cttgaaaatg gtgaagttaa
    15421 gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca tggtggcaga
    15481 tattgtaata aattgtgttc cctttgaacg ttttcgtgga gacgggctaa cagtttcgac
    15541 accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac accctaccat
    15601 tgaagctttg caattaacgg aaattgccag ccttaataat cgtgtttatc gaacactggg
    15661 ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa gaaatgatta
    15721 tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc gtattgagta
    15781 tcaaatcgac catcataaga ttcactttgt cgcgactcct agccatacca gtttctggaa
    15841 ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt tatcgcagat
    15901 gaacatgtca aggttaagac ctttttaaaa aagcacgagg tttctaaggg attgctggcc
    15961 aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa tgcaacgtat
    16021 ctattggacg ttggagacta cgttaccatt tacattcccg ctgaggaagg ctttgaaacc
    16081 ttggaggcta ttgagcatcc attagatatt ctctatgagg atgaccactt tctagtcttg
    16141 aataaaccct atggagtggc ttctattcct agtgtcaatc actctaatac cattgccaat
    16201 tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca cattgttacc
    16261 agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta tgcccatgca
    16321 cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc tttggttaag
    16381 ggagatggac atttggagcc agaaggggaa attattgctc cgattgcgcg tgatgaagat
    16441 tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc atacaagatt
    16501 gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg tcgaacccat
    16561 caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga tttgtatggt
    16621 ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct atccttttat
    16681 catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga tttcagtaac
    16741 cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat aattattatc
    16801 ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg ttggtaaaaa
    16861 tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa caaaacgctt
    16921 agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa ttaaaattta
    16981 tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac attatcctca
    17041 atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga ctgaagaaga
    17101 tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg tttacttggg
    17161 cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag ttcgcccagc
    17221 tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct tcctcatggt
    17281 tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aacatcaatc cagatgcaga
    17341 agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg gcatcgaacc
    17401 taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa gcgttgataa
    17461 ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa tcgatggtga
    17521 gttgcaattt gatgcggcct ttgttcccga aactgcagct ctgaaagctc ctggaagtac
    17581 ggtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa atattggtta
    17641 caagatggct gaacgtcttg gtggttttgc agctgtagga cctgttttgc aaggtttgaa
    17701 caaaccagtt aacgaccttt ctcgtggatg taatgcagat gatgtttaca agttaaccct
    17761 tatcacagca gctcaagcag ttcatcaata gtgaaaacta taaagcgata tactatgcta
    17821 tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag aactaaatta
    17881 ctgattggtg tcaaaaagga aaacttccaa gcgatgatat cctgtctata cacgacctat
    17941 agaaatctgt aatatacatg tccgtaaaac gataaattcc ctttttgatt ttaaatgagt
    18001 atgaaaagag aattttttca tgagaaaacg cataatattg agtgctttga cacctgctat
    18061 tatgcgtttt ctggctcttt gtcaactgta gtgggttgaa gtca
//
LOCUS       DAVFJR010000045        17801 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVFJR010000045 DAVFJR010000000
VERSION     DAVFJR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.046"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..350)
                     /locus_tag="VU722_001835"
     CDS             complement(<1..350)
                     /locus_tag="VU722_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000385025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU1772745.1"
                     /translation="MDYKVGFTEQARQDLDDIFIYYSTEFSENIAKKVITRLQQITNL
                     LTFSPEGGINFDHKIGYSLYPGNTLRMIVSKQYLLFYLIHKKEVHILRIINSRTDYLN
                     QLDHLFRNRPITKY"
     gene            complement(340..627)
                     /locus_tag="VU722_001836"
     CDS             complement(340..627)
                     /locus_tag="VU722_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU1772746.1"
                     /translation="MSTLTRDRVYNFRVNTQLFEEAKTILESKNISLSDALNLFVEQI
                     VLEKGLPIKTADQLKAEVFLGELKAELDKGYQDIIEGRLYDADEVFSQYGL"
     gene            1112..1417
                     /locus_tag="VU722_001837"
                     /pseudo
     CDS             1112..1417
                     /locus_tag="VU722_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520543.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            1414..1698
                     /locus_tag="VU722_001838"
                     /pseudo
     CDS             1414..1698
                     /locus_tag="VU722_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            2372..8812
                     /locus_tag="VU722_001839"
     CDS             2372..8812
                     /locus_tag="VU722_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU1772747.1"
                     /translation="MKKSTVLSLTTAAVILATYAPNEVVLADTSNSEDALNISDKEEV
                     VVDKETENKEKKTAVIEGKEVVSKNPVTDNNTSNEEATIKEDSNQSQGDHADSFVNKN
                     TENPKKEDRLVYIAEFKDEESREEAIKRLSNLKNTKVLYTYDRIFNGSAIETTPDNLD
                     KIKQIEAISSVERAQKVQPMMNHARREIGVEEAIDYLKSINAPFGKNFDGRGMVISNI
                     DTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKY
                     DDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGD
                     ETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATS
                     ASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGQSFKYRN
                     IGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLKGKIAVMDRIYTKDLKN
                     AFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWN
                     MINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKEL
                     YKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPI
                     VAASTVLIRPKLKEMLERPVLKNLEGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQ
                     YFASPRQQGAGLINVANALRNEVVATFKNKDSKGLVNSYGSISLKEIKGEEKYFTIKL
                     HNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKIKGANIT
                     FEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKTNFQP
                     SLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIPGTLNKGIGGEHGI
                     DKFNPAAVIQNRKDKNITSLDQDPDLFAFNNQGIHAESTSGSNVANIYPLDSNGNPQD
                     AQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAK
                     GIKSSKLKVWGDLKWDGLIYNPRGREENEPESKDNQDPATRIRGQFESIAEGQYFYKF
                     KYRLTKDYPWQVSYIPVKIDNTAPKIISIDFSNPDKIKLIAKDTYHKVKDEYKHETLF
                     ARDQKEHPEKFEEVANEVWYAGAALVDEYGDVEKNLDVTYAGEGEGRNRKLDKDGNTI
                     YEISGAGDLRGKIIEVIALDGASNFTKIHRIKFDDQADEKGMISYYLVDPDKDASKYE
                     KLGEISEEKLKNAKSPEENTNNNQAKDEDSKPDEESSVEGEASLEINKTISTIRDFEN
                     KDLKKLIKKKYREEYDFVTGGKRTVELDYQYDDKGNITAYEDESALEYETEKLDDVKS
                     KLGGVLSPSKDGHFEILGKVSNVSKNAKAYYGNDFKLIEIKASKYDPQTKTLTFDLFA
                     NTNDVVDGLSFTGDMNILVKDKGETKAKTKIRMPEKNKETKTEYPYASSYGNVIELGE
                     GDLSKNKPNNLTEMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLAGN
                     GVYSKEDIAKIQKTNPNLRVLSETTIYADSRNVKDGRSTQSVLMSALDGFNIVRYQVF
                     TFNMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYHGEEYSNVEAIKEDGSMLFIDTKP
                     VNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLH
                     IDNTRDFNVKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGV
                     HYQFLYDNVKPEVNIDPEGNTSIEYADGKSVVFNINDKRDNGFNGEIQEQHIYVNGKE
                     YKSFDDIKQLTDKTLNIKILVKDFARNTTVKEFILNKDTGEVRELKPHTVTVTMQNGK
                     EMSSKIVSEEDFILPVYKGELEKGYQFDGWEIAGFEGKKDAGYVINLSKDTFIKPVFK
                     KIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVNATV
                     PGRNDKNFENKTEVYPNEPENIANKDTNIDSKLTTNNLNKSPKTGTVSGVFTSLVAGI
                     MFTVGAFLGLKKKD"
     gene            9296..9604
                     /locus_tag="VU722_001840"
     CDS             9296..9604
                     /locus_tag="VU722_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772748.1"
                     /translation="MKKLLGIVFLVAAATVVYFGSVGWPSLDVNLWSLIPVGLFLFFT
                     LENLLKKDYKASLMCLIIAFIIANAILDLLPISSGLVIGAGVLACVGIGYLFPDKEGK
                     "
     gene            complement(9835..10194)
                     /locus_tag="VU722_001841"
     CDS             complement(9835..10194)
                     /locus_tag="VU722_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU1772749.1"
                     /translation="MDMILMKLASILLLILTLVVCIIITKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSVLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLVMYIEMIVELMAQK"
     gene            10286..11215
                     /locus_tag="VU722_001842"
                     /pseudo
     CDS             10286..11215
                     /locus_tag="VU722_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023668.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11218..11775
                     /locus_tag="VU722_001843"
     CDS             11218..11775
                     /locus_tag="VU722_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1772750.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVAKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDIERDAVLDFVSQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11768..12022
                     /locus_tag="VU722_001844"
     CDS             11768..12022
                     /locus_tag="VU722_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772751.1"
                     /translation="MDKQYLREKLDAMRQNFVESTHHERAVGVLDQVHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFEFCCKKD"
     gene            12034..14088
                     /locus_tag="VU722_001845"
     CDS             12034..14088
                     /locus_tag="VU722_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU1772752.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVKAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLTLIALTFVLFAIRFVMIYGYF
                     ACRTRRLKKKLNKYMKDMLLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLSSRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDIVELVR
                     RN"
     gene            14255..15115
                     /locus_tag="VU722_001846"
     CDS             14255..15115
                     /locus_tag="VU722_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU1772753.1"
                     /translation="MKKWWKELTDKPLVKSFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFVKDILPESLYEGVEKISREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMVSLLVSFGLQLLFAFALFLSLFGQMIL
                     DLLAHYWTKDGIIYQSLQGLAGPLIYVLLFAILVMLYYFLPNLSNRKLSYTLPGSAFV
                     LLVILGLLTLFSSYLNYYIHRLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15326..16036
                     /gene="ccdA2"
                     /locus_tag="VU722_001847"
     CDS             15326..16036
                     /gene="ccdA2"
                     /locus_tag="VU722_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU1772754.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16056..16622
                     /locus_tag="VU722_001848"
     CDS             16056..16622
                     /locus_tag="VU722_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU1772755.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSMTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKDAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTQPGFMEKDAILQTLKELA"
     gene            16633..17745
                     /gene="msrB"
                     /locus_tag="VU722_001849"
     CDS             16633..17745
                     /gene="msrB"
                     /locus_tag="VU722_001849"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU1772756.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVN"
BASE COUNT         5900 a         2873 c         3730 g         5298 t
ORIGIN      
        1 atatatttcg ttattggacg gttacgaaag aggtggtcga gttggtttag gtagtcggtg
       61 cgtgagttga taattctcag gatatggact tcttttttgt gaatgaggta aaagagtagg
      121 tattgtttag agacaatcat tctgagagtg tttcctggat agagggagta tccgatttta
      181 tggtcaaagt taataccgcc ctctggtgag aaggtgagta ggttggtaat ttgttggagg
      241 cgagtgatga ctttcttggc tatgttttca ctgaactctg tggagtagta gatgaaaata
      301 tcgtccaagt cttgtctggc ttgttctgtg aagcctactt tatagtccat actgtgaaaa
      361 gacctcgtct gcgtcgtaga gacgcccctc gatgatgtct tggtagcctt tatctagttc
      421 tgctttaagt tcgcctagga agacttctgc ttttagttgg tcagctgttt taattgggag
      481 acctttttca aggacgattt gttctacaaa gaggttgagg gcatctgaaa ggctgatgtt
      541 tttgctttct aggatggttt ttgcttcttc aaatagttga gtattgacgc ggaagttata
      601 aactcggtct cgtgtaagtg ttgacatggc atttctcctt gtaatgatat tgtagtacat
      661 atatattaca aaaaaatata gagaaagtca agggttgttt tagtaggtgt gattcgaatg
      721 tgataatgtc tttagtaaat cgaacgtgaa aatgtcccat ttggtagaat agtcatatga
      781 aaagaatcca actgaatatg aatgaaacga aaaaatatct tgtgataaaa gttatagccc
      841 aaggaaagaa aacaaagaaa cgagcctgtg tcgaacttaa tctttctgaa agacattcaa
      901 taaagcagta ggttcttgaa acctctaaga gctaggatta cgatagtgtt ttatggttaa
      961 tagttttctg tgtcactgct tttttatcgg ataggctaat ctaatctttc aacagtgtaa
     1021 tagtggtatt tcgatttcag aaagcattta attgacaagt aatgcaaatt gatgtaaaat
     1081 tacagtacaa atcttaagtg aggtgataag aatgggaaaa acagctacaa ttagtgttcg
     1141 agttgataaa ttagataaac aatcagctga ataggttttg aagcagcttg ggatgccgat
     1201 atcaacatta gttacactat tattgaaaca agtatcatta acgaagaaaa tcccttttga
     1261 tattgcattg ccagatgtgc cttcatcagt gaatgtagag gaaatgacag ctgaacgatt
     1321 tggacaaatg atgattgaag cttatcatga agcagaaaac ggtcatgttc gatctgtcaa
     1381 tgagttcttt aaagaattta aagaacggaa cgtatgacta aaataaccat taatatttta
     1441 aaaagagctg aaggagatat ggaagccatt tatcattata tcgcagatga gcttcaatcg
     1501 ccggaaactg ctatgaataa ctttgaagct attgtagagg aattgctcag tttagatatt
     1561 aaagttagat gactactagc aagaaattat tcagtgtttt atcgttttga taaggataca
     1621 gttcccatct tgagagtgtt acatcaatca agtagcttgg acagattact gtttgaaatc
     1681 gggaacaaat ccgattgaca tatacgtatt tagtcagatt atattctatt tgatggcact
     1741 tatatatagt agattgaatc taaaatagta cactgagact gctaaaaata tttctagaaa
     1801 gttagattga ctttcctaat cgatttgctc ataccttatt tcaatctact ataaaatcat
     1861 aatgaaagct ttttaagaaa catggaaaaa actgttcatt gtgctccaga tgctaaagct
     1921 taatctagct gaacaataca gatagaacct gcccattggg tgggtttttt tgtgttttaa
     1981 ggagactatt aagccagaat tttggactta tactcttcga aaatctcttc aaattatgtc
     2041 aggttgtatg gttactgact tcgtcagtct tatctggaac ctcaaaacag tgctttgagt
     2101 aacctacggt tagcttccta gtttgctctt tgatttttat tgagtactaa tcttattttt
     2161 taatgtgtgt taaaaaataa attaagacat attaattttt cttgacttaa attttttaaa
     2221 tgatatacta ttcttatgga gagctaacaa ttatatataa atgtactact ctatttccta
     2281 gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt tattatctat
     2341 tggaagttaa ataaatatgt aaggaattaa aatgaaaaaa agtacagtat tgtcattaac
     2401 cacagctgca gttattttag caacctatgc ccctaatgag gtagtcttag cagacacatc
     2461 taactctgaa gatgctttaa atatctctga taaagaagaa gtagtagtag ataaggaaac
     2521 agaaaataaa gagaagaaaa cagcagtcat tgagggaaaa gaagttgtta gtaaaaatcc
     2581 tgtgacagac aataacacta gcaatgaaga agcaacaatc aaagaagatt ccaatcaatc
     2641 ccaaggagat catgcggact catttgtgaa taaaaacaca gaaaatccaa aaaaagaaga
     2701 tagacttgtc tatattgctg aatttaaaga tgaagagtct agagaagaag caatcaagag
     2761 actatcaaat cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtag
     2821 tgccatagaa acaactccag ataatttgga caaaattaaa caaatagaag ctatttcatc
     2881 ggttgaaagg gcacaaaaag tccaacccat gatgaatcat gccagaaggg aaattggagt
     2941 tgaggaagct attgattacc taaagtctat caatgctcca tttgggaaaa attttgatgg
     3001 tagaggtatg gtcatttcaa atatcgatac tggaacagat tatagacata aggctatgag
     3061 aatcgatgat gatgccaaag cttcaatgag atttaaaaaa gaagacttaa aaggaactga
     3121 taaaaattat tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa
     3181 aatcactgta gaaaaatatg atgatggaag ggattatttt gacccacatg ggatgcatat
     3241 tgcagggatt cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga
     3301 tggaattgcg cctaatgcac aaattttctc ttataaaatg tattctgacg caggatctgg
     3361 gtttgcgggt gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga
     3421 tgttgtttcg gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca
     3481 agctattagg gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc
     3541 gacttctgct tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga
     3601 cactggaaat gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa
     3661 aaatcaaaca gttgagtttg ataaggttaa cattggagga caaagtttta aatacagaaa
     3721 tataggggcc tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc
     3781 tagtaaatta aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga
     3841 tcttaagggc aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt
     3901 taaaaaagct atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta
     3961 caatagagat aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa
     4021 aagtcaagtg ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc
     4081 tgataaaaaa actgaggtta aaaggaataa taaagaagat tttaaagata aattggagca
     4141 atactatcca attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa
     4201 agagattgac tttaagtttg cacctgacac agacaaagaa ctctataaag aagatatcat
     4261 cgttccagca ggatccacat cttgggggcc aagaatagat ttacttttaa aacccgatgt
     4321 ttcagcacct ggtaaaaaca ttaaatctac tctcaatgtc attaatggga aatcaactta
     4381 tggctatatg tcaggaacta gtatggcaac tccaatcgta gcagcttcta ctgttttgat
     4441 tagaccgaag ttaaaggaaa tgcttgaaag acctgtattg aaaaatcttg agggagatga
     4501 caaaatagat cttacaagtc ttacaaaaat tgctttacaa aatactgcgc gaccgatgat
     4561 ggacgcaacg tcttggaaag aaaaaagcca atactttgca tcacctagac aacagggagc
     4621 agggctaatt aatgttgcca atgctttgag aaatgaagtt gtagcgactt tcaaaaacaa
     4681 ggattctaaa ggtttggtaa actcttatgg ttctatttct cttaaagaaa taaaaggaga
     4741 agaaaaatat tttacaatta agcttcacaa tacatcaaac agacctttga catttaaagt
     4801 ttcagcatca gcgataacta cagattctct aactgataga ctaaaactgg atgaaacata
     4861 caaagatgaa aaatctccag atggtaagca aattgttcca gaaatccatc cagaaaaaat
     4921 caaaggagca aatatcacat ttgagcatga tactttcact ataggcgcaa attctagctt
     4981 tgatttaaat gcggttataa acgttggaga ggctaaaaat aaaaataaat ttgtagaatc
     5041 atttattcat tttgagtcag tggaagaaat ggaagctcta aactccaatg ggaagaaaac
     5101 aaattttcaa ccttctttgt cgatgcctct aatgggattt gctgggaatt ggaaccacga
     5161 accaatcctt gataaatggg cctgggaaga gggttcaaaa tcaaaaacaa tggaaggtta
     5221 tgatgatgat ggtaaaccaa aaattccagg aaccttaaat aagggaattg gtggagaaca
     5281 tggtatagat aaatttaatc cagcagctgt tattcaaaac agaaaagata aaaatattac
     5341 atcactagac caagacccag acctatttgc ctttaacaac caaggtattc atgcagaatc
     5401 cactagtgga tctaatgttg ctaacattta tcctttagat tcaaatggaa atcctcaaga
     5461 tgctcaactt gaaagaggat taaccccttc tccacttgta ttaagaagtg cagaagaagg
     5521 attgatttca atagtaaata caaataaaga gggagaaaat caaagagact taaaagtcat
     5581 ttcgagagaa cactttatta gaggaatttt aaattctaaa agcaatgatg caaagggaat
     5641 caaatcatct aaactaaaag tttggggaga tttgaagtgg gatggactca tctataaccc
     5701 tagaggtaga gaagaaaatg aaccagaaag taaggataac caagatccag ctactaggat
     5761 aagaggacaa tttgaatcaa tagctgaggg tcaatacttc tacaaattca aatatagatt
     5821 aaccaaggat tatccatggc aagtttctta tataccagta aaaattgata atacagctcc
     5881 aaaaattatt tcaattgatt tttctaatcc agataaaatt aaattgatcg caaaagatac
     5941 ctaccacaag gtaaaggatg agtacaaaca cgaaaccttg tttgctagag accaaaaaga
     6001 acatcctgag aaatttgaag aagtagccaa cgaagtatgg tatgcaggtg cagctcttgt
     6061 cgatgagtat ggagatgttg agaaaaatct tgatgtaact tacgccggag agggtgaggg
     6121 aagaaatagg aagcttgata aagatggaaa tactatctac gaaattagcg gagcaggaga
     6181 tttaagagga aaaatcatcg aagtaatcgc cctagatggt gcaagcaact tcaccaaaat
     6241 ccatagaatt aaatttgatg accaagctga tgaaaaagga atgatttctt attacctagt
     6301 agatcctgat aaagatgctt ctaaatatga aaaactaggt gaaatttctg aagaaaaact
     6361 caaaaatgca aagagcccag aggaaaatac caataataat caagctaagg atgaagattc
     6421 aaaaccagat gaagaaagtt cagttgaggg agaagctagc cttgaaataa ataaaactat
     6481 ttcaacaatt agagactttg aaaataaaga cctaaagaaa ctcattaaaa agaaatatag
     6541 ggaagaatat gactttgtaa ctggtggaaa aagaacagta gaacttgatt atcaatatga
     6601 cgataaagga aatataactg cctatgaaga tgagagtgct ctagaatatg aaactgagaa
     6661 acttgatgat gttaaatcaa agcttggtgg agtattaagc ccatcaaagg atggacattt
     6721 tgaaattctt ggaaaagtaa gtaatgtatc caaaaatgct aaggcttact atggcaatga
     6781 cttcaaatta atagaaatta aggcaagtaa atacgaccca caaactaaaa ctctaacctt
     6841 tgacttattt gcaaacacaa atgatgtagt cgatggtcta tcctttacgg gtgatatgaa
     6901 tatccttgta aaagataagg gtgaaacaaa agctaaaact aaaattagaa tgcctgaaaa
     6961 aaataaggaa actaaaacag aatatcccta tgcatcaagt tatgggaatg taatcgaatt
     7021 aggagaagga gatctttcaa agaacaaacc aaacaattta actgaaatgg aatctggtaa
     7081 aatctattct gattcagaaa aacaacaata tctgttaaag gataacatca ttctaagaaa
     7141 aggctatgca ctaaaagtga ctacctataa tcctggaaaa acggatatgt tagcagggaa
     7201 tggagtctat agcaaggaag atatagcaaa aatacaaaag accaatccta atctaagagt
     7261 cctttcagaa acaacaattt atgctgatag tagaaatgtt aaagatggaa gaagcactca
     7321 atcagtatta atgtcggctt tggacggctt taacattgta agatatcaag tgtttacctt
     7381 taacatgaat gataaagggg aagctatcga taaagatgga aatcttgtga cagattcctc
     7441 taaacttgta ttatttggta aagatgataa agagtatcat ggggaggaat attctaatgt
     7501 agaagctata aaagaagatg gctccatgtt atttattgat accaaaccag taaacctttc
     7561 aatggataag aactacttta atccatctaa atctaataaa atttatgtac gaaatccaga
     7621 attttattta agaggtaaga tttctgataa gggtggtttt aactgggaat tgagagttaa
     7681 tgaatcggtt gtagataatt atttaatcta cggagattta cacattgata acactagaga
     7741 ttttaacgtt aagcttaatg ttaaagacgg tgacatcatg gactggggga tgaaagatta
     7801 taaagcaaac ggatttccag ataaggtaac agatatggat ggaaatgttt atcttcaaac
     7861 tggctatagc gatttgaatg cgaaagcggt tggagtacac tatcaatttt tatatgataa
     7921 tgttaaacct gaagtaaaca ttgatcctga gggaaatact agtatcgaat atgctgatgg
     7981 aaaatctgta gtctttaaca tcaatgataa aagagataat ggattcaatg gtgagattca
     8041 agaacaacat atttatgtaa atggaaaaga atataaatca tttgatgata ttaaacaact
     8101 aacagataag acactaaata ttaagattct tgtaaaagat tttgcaagaa atacaaccgt
     8161 aaaagaattc attttaaata aagatacggg agaggtaaga gaattaaaac ctcatacggt
     8221 aactgtgacc atgcaaaatg gaaaagaaat gagttctaag atagtgtcgg aagaagattt
     8281 cattttacct gtctataagg gtgaattaga aaaaggatac caatttgatg gttgggaaat
     8341 tgctggtttc gaaggtaaaa aagatgctgg ctatgttatt aatctatcaa aagatacctt
     8401 tataaaacct gtattcaaga aaatagagga gaaaaaggag gaagaaaata aacctacttt
     8461 tgatgtatcg aaaaagaaag ataacccaca agtaaaccat agtcaattaa atgaaagtca
     8521 cagaaaagag gatttacaaa gagaagatca ttcacaaaaa tctgattcaa ctaaggatgt
     8581 caatgctaca gttcctggta gaaatgataa aaactttgaa aataagactg aagtttatcc
     8641 taatgaacca gagaacatag ccaataaaga taccaatatc gatagtaaat taactactaa
     8701 caatcttaat aagtcaccaa aaaccggaac agttagcgga gtattcacgt cattggttgc
     8761 cggaataatg tttaccgtag gcgcatttct tggattaaag aaaaaagatt aagattaaga
     8821 caaaagctat agatgaaaaa atggtttatg tactgagata gtatgatgat gaaacagttt
     8881 tgtgaaaata gctatttata actcaattat ttagtttact ttactattga tactcttttt
     8941 ggatctatta atagacttag tttcgacaac taatgaattg attgaaaggg ttagtattga
     9001 caatattgat tagaaaatag agtctatcaa aatttaaagg tcaatagagg tgatgagata
     9061 atttcaagga attaagtagt gtttggttgc ttaattcctt tttatttgga aggaagtttt
     9121 tcacctgctt ccttatttta tcgctattat tcaaccactt agactgagat tgagaccaga
     9181 taggcaaacg aacttgttct tgaaactgac ctctgctata atgatttttg taagagacgc
     9241 aaggcgtcga tattagacaa ctcaagttcc taaaaaagaa atcggagata aagaaatgaa
     9301 aaaattattg gggattgtct ttttagtagc agcagcgaca gtagtgtatt ttggttctgt
     9361 tggctggcca agtttagatg tcaatctctg gtcactgatt ccggtaggat tgttcctctt
     9421 tttcactcta gagaatcttt tgaaaaaaga ctacaaggct agtctgatgt gtttgattat
     9481 tgcctttatc atcgcaaatg caattttgga cctgttgcca atttcaagtg gcttggtgat
     9541 tggagcaggt gtgctggctt gtgtaggtat tggttacctc tttcctgata aagaaggaaa
     9601 ataatactct tcgaaaatct cttcaaacca cgtcagcttc gccttgccgt atatatgtga
     9661 ctgacttcgt cagtcttatc tacaacctca aaacagtgtt ttgagtagcc tgcggctagc
     9721 ttcctagttt gctctttgat tttcattgag tataagaatt attgaaaaag atataaagaa
     9781 aaacacttca atcactgtat ttcagtttga ttgaggtgtt ttagatttag ttttttattt
     9841 ctgggccatc aattcaacaa tcatctcgat atacatgacc agggttaata agaatcctgt
     9901 acgccagaag aatttgatga atttaggata gtaaaagcta cgttttttca aaaggaagaa
     9961 aaaaacgaga ataatggcta gaactgagag ggctagcccc agtctaggga ggaaattatg
    10021 ggtaaaggtt ttagctgtga tcaggtagta ctcaaatacc aagactggaa aggccaaatc
    10081 cgcaaagttt cgtcctagtt tttttaatct aaaaagtttg gttatgataa tgcagactac
    10141 tagagtcagt atcaataata aaatagatgc taatttcatt aaaatcatat ccatattgta
    10201 tcataaaaaa aggctaatgg aaacgagaaa cagaggaatt tataggaaag tcaggctttt
    10261 gagattgtgg gtgatttttg ttataatgag agttatgaaa tcttataata ccttgaatga
    10321 ttattatcga aaactctttg gagaaaagac ctttaaagtc cctattgatg cgggatttga
    10381 ctgtcccaat cgtgatgaaa ctgtggctca tggaggctgt actttttgta cggtttccgg
    10441 ttctggagat gccattgtgg caccagatgc gcctatccgt gagcaatttt ataaggaaat
    10501 tgactttatg catcgtaagt ggccaggtgt tcagaagtat ctggtttatt ttcaaaattt
    10561 tacaaacacc catgaaaagg tggaagttat tcgagagcgt tatgaacagg ctatcaatga
    10621 cccaggtgtg gtaggaatca atattggaac gcgcccagac tgtttaccag acgaaaccat
    10681 cgaatatttg gctgagttgt cggagcgcat gcatgtgagg gttgaattag gcttgcagac
    10741 tacttatgaa gcaacctctg acctgattaa ccgcgcgcat tcttatgaat tgtaggtgga
    10801 aacggtcaag cgtttgagaa agtatccaaa aattgagatt gtttcccatt tgatcaatgg
    10861 tttacctggt gaaactcatg agatgatggt tgaaaatgtc cgccgttgtg tcacggataa
    10921 cgatattcaa gggattaaac tgcatttgct tcacctgatg accaatacac gtatgcaacg
    10981 agattatcac gaaggacgtt tgcagttgat gagccaggac aaatatgtta aggtcatctg
    11041 tgaccaactg gaaatcattc ccaaacatat tgtcatccat cgaattacag gagatgcacc
    11101 gagagatatg ctgattggtt ccatgtggag cctaaataaa tgggaagtgc taaatgctat
    11161 tgaaactgaa atgcgacgtc gtggaagtgt tcaaggatgt aaaacaggag tttgaaaatg
    11221 aaaagaccac ttgagatggc acatgatttt ttggctgagg tcgtgacaaa agaggatgtc
    11281 gtagtggatg cgactatggg aaatggtcat gacacgcttt ttttagccaa gctagccaag
    11341 caagtctatg cctttgatat tcagaagcaa gccttggaaa agacccaaga gcgtttgcat
    11401 caggctggct tgacaaatgc ccagttaatc ttgcaaggcc atgagacact ggaccagttt
    11461 gtggcaaaag ctaaggcagg gatttttaat ctgggctatt tgccgtcagc tgataagtct
    11521 gtcatcaccc gaccgcagac aacgattgag gcattagaaa agctatgtgg cttacttgtc
    11581 aaaggtggac gaattgctat catgatctac tatggtcatg aaggaggcga catcgagagg
    11641 gatgctgtct tggattttgt tagccagttg aaccaacaag agtacacagc tgccatttac
    11701 cgaactttaa accaagtcaa caacccacca tttttagtaa tgattgaaaa attagagaga
    11761 tacagacatg gataaacaat acctacgtga aaagctggat gccatgcgcc agaattttgt
    11821 tgaatcaacc caccacgaac gagcggtggg cgtgctagac caagtgcata tgagcaaaaa
    11881 aatgcttaaa atcaagaaaa aattagttgc tcttgaaatg gaacggtgcc agagaaaaat
    11941 tgagcacaaa gattgttcca agattgacca aaaaatcaaa gagcagaagg agatatttga
    12001 attctgttgt aaaaaagatt aaggaggacg tgcgtggaat tactgattta cctcatccta
    12061 tttttactgg tcttgattgt ctcaagtaca accaataagc tcctaccctt tttgcctctc
    12121 cctttggtgc agattctttt gggaattgta attggtctct ttttacccaa tactgacttt
    12181 caccttaata cggagttgtt tttggcactg gttatcggac ccttgctttt ccgagaggct
    12241 gaagaagcag atgttaaggc tattttaaaa cactggcgaa tcattgttta tctcatattt
    12301 ccagtgattt ttatctcgac cctgagtttg ggtggcttgg cccatcttct ttggttcagc
    12361 cttcccttgg cagcttgctt ggctgttggg gcagcccttg gtcctacgga cttggtggcc
    12421 tttgcctctc tttcggagcg ttttagcttt cctaagcgcg tgtccaatat tcttaagggc
    12481 gaaggactct tgaatgatgc ttctggtttg gtggcttttc aggtagcttt gacagcttgg
    12541 acaactggag ctttttctct ggggcaagct agcagttcgc tcatcttttc aatcctaggc
    12601 ggttttttaa ttggattttt aacagccatg accaaccgct tcctccatac cttcttgcta
    12661 agtgtgcgcg caacggatat tgccagtgaa cttttactag aattgagttt gcctctagtg
    12721 accttctttc tggcagaaga agtccacgtt tcagggatta ttgccgtcgt agttgctggg
    12781 attttaaagg caagtcgctt caagaaaatc acgctcctcg aagcccaagt ggacacggtg
    12841 accgagacgg tctggcatac agtgaccttt atgctcaacg gttctgtctt tgtgatttta
    12901 gggatggagc tggaaatgat agcagagcct atcttaacca atccaatcta taatccctta
    12961 cttttattgc taactcttat agcccttacc tttgtcctct ttgctattcg ttttgtcatg
    13021 atttatggct attttgcctg taggacccga cgcctcaaga aaaagctaaa taagtatatg
    13081 aaggacatgc ttctcttgac cttttcaggt gttaagggaa cggtgtcgat tgctacgatt
    13141 ctcttgatac caagtaatct agaacaggag tatcctctct tgcttttcct tgttgcaggt
    13201 gtgacgcttg tcagcttttt aacaggtctc ttggtcttgc ctcatctttc tgatgaagag
    13261 gaagaaagca aggattatct catgcatatc gccattttga atgaagtaac gctagagttg
    13321 gaaaaagagt tggaagacac cagaaataaa cttcccctct atgcggctat tgacaattat
    13381 catggacgta ttgaaaatct cattttaagc caagaaaacc aggatgatca agaagactgg
    13441 gctgctttga aactcttgat tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa
    13501 gaggggaaca ttagcaatcg tgcttaccga gtttaccaac gttatctgaa aaatatagaa
    13561 caaggaatca atcgtaaact ttcctcaaga ctaacctatt atttccttgt ttctttgcgg
    13621 attttacgtt ttctccttca tgaagttttt actctcggaa agaccttccg tagctggaag
    13681 aacaaggagc aaagccgtct ccgtgctctt gattatgacc aaattgcaga gctctatctt
    13741 gccaatacag agatgattat tgaaagtttg gaaaacctga agggagtcta cagacgctct
    13801 ttgattagtt ttatgcagga gtctcgtctt cgagaaacag ctattatcag cagtggtgcc
    13861 tttgtcgaac gggttatcaa tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc
    13921 tattatctgg agcgcaagtt gattttcgaa tacgaagaaa aacgattgat tacgactaag
    13981 tatgccaaga aattacgaca aaatgtaaat aatttagaga actattcctt gaaggaagct
    14041 gccaataccc tgccgtatga tatagtggaa ttggtaagaa gaaattagtt aatactcttc
    14101 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat gtatgagagt cttatctaca
    14161 acctcaaaac agtgttttga gcagcctgcg gctagcttcc gagtttgctc tttgattttc
    14221 attgaggata agattgtaag tgaaggagtg tgacatgaag aagtggtgga aagagctgac
    14281 agacaagcct ttagtaaaat cctttttgca ttattatcaa gcatcagata gtgagttgac
    14341 cagtgtcgca gtagcctact attggttgat ttcgattttt cccctgcttt tggtggtggt
    14401 caatatcctc ccctattttc agattcctgt gggagaattt ctgggatttg tgaaagacat
    14461 cctacccgaa agtctctatg aaggtgtaga aaaaatatcc agagaagtct tgacgcaacc
    14521 ttcaacaggt ttattgagct tttctgtctt atcggcgtta tggagctttt caaaatctat
    14581 gaatttcctg caaaaagctt ttaacaaggc ttatggcgtc gaaaagagtc gcggacttat
    14641 ttcccatcag atggtgagtc tcttagtgag ttttggtttg caactactat ttgcttttgc
    14701 cttgttttta agcttatttg ggcagatgat tttggattta cttgctcatt attggacaaa
    14761 agatggcatt atctatcagt ctttacaagg gttggcaggc cctctgattt acgtcctact
    14821 ctttgctatc ttggtcatgc tttattattt tcttcccaat ctatctaaca ggaaactgag
    14881 ctatacccta ccaggcagtg cctttgttct cttagtgatt ttaggtttac taactttgtt
    14941 ttctagttat ctcaattact acatccatcg tttagtggac gtccgaattt taggttccgt
    15001 tcttcttgtt gttatgatgt tttggtttat cttgattgct aaaattgtta tcctaggcgc
    15061 ggttatcaat gccagtatgc agagtttgaa agatccggtc tttaaaaaag actaactatt
    15121 tatccattac aaaagcgcat agtatcaaga ctttatagaa ccttgatact atgcgctttt
    15181 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15241 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15301 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15361 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15421 ggtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15481 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15541 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15601 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15661 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    15721 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    15781 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    15841 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    15901 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    15961 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16021 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16081 ttggagcagg ttcgctcctt tgtttgacgg cttgttcagg caagtccatg actagtgaac
    16141 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16201 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16261 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16321 ctagtcttcc agatacggat gagattgcta aggatgctgg tgatgactat gtggtcttga
    16381 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16441 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16501 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16561 aaacacaacc aggattcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16621 aggaggtgtc ctatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16681 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    16741 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    16801 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    16861 ttctcacggg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    16921 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    16981 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17041 accagcaaaa ataaacaagg aaatgatgtg ggaacccagt accgtactgg tgtttattac
    17101 acagatgaca aggatttgga ggtgattaac caagtctttg atgaggtggc taagaaatac
    17161 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17221 caccaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17281 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17341 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17401 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17461 ctcttttcat caaaggacaa gtttgagtct ggttgtggct ggcctagttt tacccaaccc
    17521 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17581 gtgcggagcc gggtaggaga ttctcacctt ggccatgtct ttacggatgg tccacaggac
    17641 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    17701 atggaagaaa aaggctacgc ttatttacta gattatgtta attaatactc ttcgaaaatc
    17761 tcttcaaacc acgtcagcgt cgtcttaccg tatgtagggt t
//
LOCUS       DAVFJR010000046        16857 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVFJR010000046 DAVFJR010000000
VERSION     DAVFJR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.047"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            38..1756
                     /locus_tag="VU722_001850"
     CDS             38..1756
                     /locus_tag="VU722_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU1772757.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLTRRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            1867..2214
                     /locus_tag="VU722_001851"
     CDS             1867..2214
                     /locus_tag="VU722_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU1772758.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(2492..3328)
                     /locus_tag="VU722_001852"
     CDS             complement(2492..3328)
                     /locus_tag="VU722_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772759.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYVDF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(3341..3970)
                     /locus_tag="VU722_001853"
     CDS             complement(3341..3970)
                     /locus_tag="VU722_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1772760.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(3980..4621)
                     /locus_tag="VU722_001854"
     CDS             complement(3980..4621)
                     /locus_tag="VU722_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1772761.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(4767..5996)
                     /locus_tag="VU722_001855"
     CDS             complement(4767..5996)
                     /locus_tag="VU722_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU1772762.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(5986..7152)
                     /locus_tag="VU722_001856"
     CDS             complement(5986..7152)
                     /locus_tag="VU722_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU1772763.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAISIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VWASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFMPTKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFMIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVISGLYELEGEEVKSEQ"
     gene            7296..8309
                     /locus_tag="VU722_001857"
     CDS             7296..8309
                     /locus_tag="VU722_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU1772764.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKTGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIRLSTDGQYLYASNRGHNSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIAVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(8355..8774)
                     /locus_tag="VU722_001858"
     CDS             complement(8355..8774)
                     /locus_tag="VU722_001858"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU1772765.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDEDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VU722_001859"
     CDS             complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VU722_001859"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU1772766.1"
                     /translation="MSSGKIAQVMGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKILVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(10277..11155)
                     /locus_tag="VU722_001860"
     CDS             complement(10277..11155)
                     /locus_tag="VU722_001860"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU1772767.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(11171..12676)
                     /locus_tag="VU722_001861"
     CDS             complement(11171..12676)
                     /locus_tag="VU722_001861"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU1772768.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(12691..13227)
                     /locus_tag="VU722_001862"
     CDS             complement(12691..13227)
                     /locus_tag="VU722_001862"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU1772769.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAYPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VU722_001863"
     CDS             complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VU722_001863"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU1772770.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VU722_001864"
     CDS             complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VU722_001864"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU1772771.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(14486..14686)
                     /locus_tag="VU722_001865"
     CDS             complement(14486..14686)
                     /locus_tag="VU722_001865"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU1772772.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(14761..15768)
                     /locus_tag="VU722_001866"
     CDS             complement(14761..15768)
                     /locus_tag="VU722_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU1772773.1"
                     /translation="MQNYYTTKGKHLTIDSRCLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGCFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(16225..16587)
                     /locus_tag="VU722_001867"
     CDS             complement(16225..16587)
                     /locus_tag="VU722_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772774.1"
                     /translation="MENKESHKSQEIGNLLRVYNRSKREETESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYL"
BASE COUNT         5123 a         3688 c         3064 g         4982 t
ORIGIN      
        1 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
       61 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
      121 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
      181 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
      241 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtcgcaat
      301 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
      361 taaacacggc atcaaatctt acgtatttga aagccttcgt ccgactccag aactatcatt
      421 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
      481 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
      541 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
      601 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacataga
      661 ataccttaaa gaggttaagg acataaacat caacccagcc ttgattgaag aatttggtaa
      721 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttga ctcgtcgtgc
      781 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
      841 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
      901 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
      961 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     1021 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     1081 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     1141 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     1201 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     1261 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     1321 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     1381 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     1441 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     1501 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     1561 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     1621 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     1681 tgtaggggaa accaacgaag aatcacaagc taagattact aacatcgaag cagaaatcaa
     1741 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     1801 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     1861 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     1921 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     1981 ccttactgcc gtaaatttgc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     2041 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     2101 cgttatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     2161 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgtaggatt gtaaaaaatc
     2221 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     2281 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     2341 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     2401 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     2461 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     2521 ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc ttgtaaagac
     2581 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     2641 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     2701 cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     2761 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     2821 tattcttcaa aatttctgga tttgcttcaa agtccacata accagatgaa ccagcttgag
     2881 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
     2941 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
     3001 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
     3061 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
     3121 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
     3181 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
     3241 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
     3301 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
     3361 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
     3421 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
     3481 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
     3541 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
     3601 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
     3661 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
     3721 gaaaatcttg gaagacaaat cccagtagat tgcgcttctg caattcatcc agctctaaag
     3781 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
     3841 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
     3901 tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg atatttcgta
     3961 attctaacat ggcagcctcc tatctataat aactatactt cttctcaact tttttggaaa
     4021 taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac ataggaacta
     4081 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
     4141 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
     4201 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
     4261 agaccttggc ggcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
     4321 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcggtcta
     4381 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
     4441 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
     4501 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
     4561 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
     4621 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
     4681 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
     4741 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
     4801 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
     4861 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
     4921 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
     4981 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
     5041 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
     5101 tcagcgtctt cttttgcagc aagaagataa ttttctgcac cactagcatc atgcaattca
     5161 taagaaaatt gtgaagcagc cagcaagagg cgagtttcaa agggattttt ctctaatcct
     5221 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
     5281 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
     5341 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
     5401 tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac
     5461 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
     5521 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
     5581 aactctgcca aacccaacat caagagagaa tcctctgagt aggtcaaggc ctccaataat
     5641 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt caaaaccaaa
     5701 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
     5761 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
     5821 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
     5881 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatactca
     5941 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
     6001 gacttcctca ccctctaatt catataggcc actgattacc ttataccatt cgaaaatggc
     6061 tgaaatgaca accttagcag aggcataaac cggaataccg agcaagactc cccagatacc
     6121 aaacatggat cctgaagtta gcaagacaaa gagaacatta atgggatgga tgtttaattg
     6181 acttcccaaa atcaatggag aaacaaaacg gccttcaata gtttgttcta cgataaagac
     6241 aatcactact ttcaaaagca tgactggccc agcaatcaag cccaatacta gggcaggaag
     6301 catggctagg aagctgccaa gataaggaac caaatttaaa ataccagcag taacacctag
     6361 cgtaaccgca tagcgtagac cgataatctt gaagaaaatc ataaacatta ctgctacaat
     6421 aatagctact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgacaa
     6481 aacctgtcct acaggttctt tcaattttgt cggcatgaat tgggtcaaat agttacgcaa
     6541 gccttttcca tcacgcaaga gataaaagag catgaaagga acaataatca aggcaacaat
     6601 cacttgagaa gccccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
     6661 actcgcccaa actgtagcct gacttgagaa gtttgtcaaa acttgttcta actgaggtct
     6721 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
     6781 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
     6841 tgccaagccc caaatgataa agagagctat gatgacaaag acaatgctga tggctatgac
     6901 gcgattgact ttgtgttttt ccatccaatc aacaatagga ttcaacaaat aatataacaa
     6961 accagacaga atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
     7021 aaaactaatc ttacttaaaa taaaaagatt gagtcccaat aataaggtta ccaaaaatac
     7081 cgtaatggcc ttgttatcca aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
     7141 tttttgctcc ataaatactt cctttctatt gttctcccat tataccattt ttgaaacaaa
     7201 ataactcttt tttaaagtgc ttacatctaa ttggatgtct ttaattggct tgtttttgtg
     7261 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
     7321 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
     7381 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
     7441 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
     7501 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
     7561 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caggtccttg
     7621 tttataaacg ccaggaagat ggtagtcttc tacttagcga tatggatcaa cacagtggcc
     7681 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
     7741 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
     7801 aaggaaaatt atctaagctc tatacctatc acagcaagac aggagcaggc tcacgccata
     7861 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
     7921 aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt tcaactttac
     7981 cagaagctta cgaaggcttt aatggaaccg ctgctattcg tctctctaca gacggtcaat
     8041 acctctacgc ttctaaccgt ggtcataatt ctatcgcagt atataccatc cttgcggacg
     8101 gtagcttaga gttattagaa atcgttccaa cacatggtca gactccacgt gattttgatt
     8161 tgacacccga ccaaaaattt ctcattgctg tccaccaaga ctctgacaat gcaactgtct
     8221 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
     8281 aagcggtctg tatccgtttt gctccttaag aaaacataaa aaatgaactt ggaattttca
     8341 agttcatttt tttcttatag tctatttccg acattgatac ggttaatggc acgttgcagt
     8401 gcaatcttcg cacgacgttc ttggtcaatc aagtgtttgt cttgtgcttc ttcaattgca
     8461 cgttctgcac gaagtttggc acgttctgca cgactgatat cgatatcacg agcacgttct
     8521 gcagagtcag cgacgattgt aatcatatca ttggcaattt caataacacc gccgtttact
     8581 gcaatccagt tcacgtgatc ttcgtcatca atacgtttta cctttacttc atcaactgct
     8641 aaaaccgcaa tcatattttc atgtcgtggc aagatcccca tctcaccatc cagagttcga
     8701 accgatacat agctggcatg gtgatcatag acgaggccat ctggtgtcac gatctggaca
     8761 gttaactgag ccatagatca cctcttaaaa tcccattttt tcagcttttg caatcacatc
     8821 ttcgatagaa cctacaccac ggaaggcatc ttctggcaag tggtcgtatt taccatcaag
     8881 gatttcctta aagccacgta cagtttcagc aactggaaca taagaacctg gctgaccagt
     8941 aaattgttct gcgacgttga agttttgtga caagaagaac tggatacgac gggcgcgagc
     9001 aaccaagatc ttttcttcat cagaaagctc atccatacca aggatagcaa tgatatcttg
     9061 caattcatgg taacgttgaa ggacacgttt tacttcagca gcaactgcat agtgctcttc
     9121 tccaacgatt tcaggtgcca aggcacgtga gcttgaagca agtgggtcaa cggctgggta
     9181 gatacccaat tgtaccaact tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc
     9241 tgttgctggc gctgggtcag tatagtcatc cgctggcaca tagatagcct ggatagaggt
     9301 tacagaaccc ttcttggttg atgtgatacg ttcttgcaat tgacccattt ccgtagcaag
     9361 tgttggttgg taaccaacgg ctgatggcat acgacccaaa agggcagata cttctgaacc
     9421 agcctgagtg aaacggaaga tattatcgat aaagagaagc acgtcttggc cttccacatc
     9481 acggaagtat tcagcgattg tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg
     9541 ctcattcatc tgaccaaaga ccatggctgt tttctcgata acgcctgatt ctttcatttc
     9601 ccagtaaagg tcattcccct cacgagtacg ttccccaaca ccagcaaata ctgaaatacc
     9661 accgtgctct tgggcaatgt tgtgaatcaa ttcttggatt aagacggttt taccaactcc
     9721 ggcaccaccg aaaagtccaa ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac
     9781 cttgatccct gtttcaagga tttcagaaga ggtagacaac tcatcaaaag ttggagcttt
     9841 tttatgaatt ggctgacgct ctgcgtcttc tgtaaaagga gcttccaagt caatggtatc
     9901 tcccaaaacg ttgaagacac gtcccaaagt ttctttacct actggtacag agattggacg
     9961 acctgtgtcc aatacttcca ttccacgagt caacccatct gttgattcca tggcgatagt
    10021 acgaaccata ccatctccta actccaaggc tacttcaagg acgatttttg tttttctttc
    10081 gtcatttttg tagacgacaa gtgcattatt aatctcagga agtttttccc ctgctgcaaa
    10141 caaaacgtct acaacgggac ccataacctg agcaatttta cctgaactca tctccttctc
    10201 ctattctata taagatactg tcggttccta gctcaactag gtcctaagtt cattttcata
    10261 cgagatggac tagagcctat tctaaggcac tagcacctgc tacgatttct gtaatttctt
    10321 gtgtaatcgc cgcctgtctg gcacggttat actgaattgt caaatcattg atgactttct
    10381 tagcattatc tgtcgctgtt tgcatggctg tcatacccgc agcattctca gctgtcttgg
    10441 catcgataat ggcaccgtaa atcatacttt ctgcaaactg aggcaacaac tgctccagaa
    10501 tttcttctcg gctggtttcc aattcaaaag tcaagctgta ctcttcatcc gcttcatttg
    10561 gatccaagtc aacaatcgga agcatttgtt ccacacgcat ttgactggtt agcgtattga
    10621 catggtggtt gtagcaaaca taaagctcat caaagagttc attttggtac atttcaacag
    10681 tttttgaaat aatcttacga acttgatcaa agctaggttg gtctgacaag ccacgtaatt
    10741 cataaagtgg ttgaataccg cgagccttaa agaaatcagc tcccatccca ccgatacaga
    10801 tcatttcaaa acctttaccg tctgggtggt attcttcttt caactccata acagctttca
    10861 aaatagagga attataacct ccaaccaaac cgcggtctga agtgataacg atatagcctg
    10921 tcttcttcac agaacggcta atcaacatcg gattagttga agcaccagct ccattaccat
    10981 gaaggatatc tgtcaaaagt ttacgcactt tctgagcgta aacttggaag ttgcgagcag
    11041 cttcttcaga acgacctagc ttagcagccg ataccatttg catggcatta gtgatttgac
    11101 tcgtattttt tgttgaggcg atttttgttt taatatcatt tagagatact gccatctgac
    11161 acctctattc ttattggaag ctagattgat tgagaaactc tgtaatcgca gcatccaaga
    11221 ctgcttcttc tggcaagtct tttgtatcac gaatggtttc caaaatctct ggatgttgag
    11281 catcaaagaa ggcatggaac tcttcctcga aacgaacaat atcatctact ggaacagtat
    11341 ccaagaaacc atgtgtcaaa gcataaagaa tggttacttg tttctcaaca ggtaatggtt
    11401 tgtgaacagg ttgtttcaag acctcaacgg tacgacgtcc acggttcaac ttagcctgtg
    11461 ttgctgcgtc caagtcagaa ccaaacttag taaaggcttc caactcacgg tatgaagcaa
    11521 ggtcgatacg aagtgtacca gcaaccttct tcatggcttt gatttgtgca gaaccaccta
    11581 cacgagatac agatgaaccc gcatcgatgg ctggacgaat acctgcattg aaaaggccat
    11641 cgccaaggaa gatttgtcca tcagtgatag aaatcacgtt ggttgcgata taggctgaga
    11701 tatctcctgc ttgtgtctcg ataaatggta gggctgtaat tgatccacca ccaagttcat
    11761 cagaaacttt agctgagcgc tcaagcaaac ggctgtggag atagaaaaca tcccctggga
    11821 aggcttcacg acctggagga cgacgaagca agagcgacag ttcacgataa gctaccgctt
    11881 gttttgatag atcatcgtat acaatcaaaa catgcttacc ttgatacata aattcttccg
    11941 ccatagcaac cccagcataa ggagctagga agagcaatgg agatggttgt gaagcagagg
    12001 ctgtcacaac gattgtgtag tccaaggcac cgtactgacg aagtgtttct acttgcgtac
    12061 gaactgttga ttctttttgt ccaatcgcga cgtagataca gatcatatct tgatcttttt
    12121 ggttcaagat tgtatcaatc gcaatggttg ttttccctgt ctgacggtca ccgataatca
    12181 actcacgttg accacgacca atcggtacaa gggcgtcaat agctttcaaa ccagtttgca
    12241 atggttctga aacagactta cgttgcataa caccaggagc tggtgcttct actggacgag
    12301 ttttatcagt gtggatttct ccaagaccgt caactggacg accaagcgga tccacaacac
    12361 gaccaatcag actttcacct acagggactt ccatgatttt ccctgtacgg cggattgtat
    12421 cgccttcacg gatatctgta aagtcaccta ggatgataat accaacgtct gttgactcca
    12481 agttttgagc cataccataa gagccgtttt caaaattcaa caactctcca ctcatggcat
    12541 tttcaaggcc gtgagcacgc gcgataccat ccccgatata ggttacaaca cctgtttcag
    12601 tcacatcaaa attgggtttg aaattttcaa tttgttgctt aattaaagcg ctgatttctt
    12661 gtgcgttaat tgccaaaaga acaccacttt ctatttcaaa ttttctttaa caactttaag
    12721 ttgttgttta atactcacat caattgtctt gtgattggca aaaatgacaa aaccaccaat
    12781 gagactttca tcgatttgtt cttttacact ccttactttc agagacattt ttttctcaat
    12841 caaagggagc aaacgagtct tctgttcatc agttagagga taagcagacg taatcgtcac
    12901 ttcaaatcga tttgtttctt tttcaagtcg gttcaagcaa tctacaagca catcataaaa
    12961 aagatttgct ctgtgattgt aggccagaac ctggataaag ttttgtaata aaggtgacac
    13021 agaatcttgg aaaaaagcaa ttgttttttc cttatccgac tcgtctactg ccacttgttt
    13081 taaaaaagaa ggcagacctg ttttttcaac aacttgcttg atttgagtca agtctgaaaa
    13141 gatacggtct tcttctcctt tttcaagtac caattggaca aaaggcatgc tgtatttttc
    13201 aattaccttt actgttttct tgtccattaa gcttctccta gctgatcgat atactgatca
    13261 atgagtgctt tatgggcatg actgtcaagg ttttgtgaga tgattttacc agctaagctg
    13321 atggtcaaat ctgcgacctc acccttaaca ctctgtaaag cttctacttt attttgagca
    13381 atttcttgat tggctttttc ttttaagtgt cctgcttcta gtttagcatc tgctaagata
    13441 ttagccttac tttgctcagc tgtttccttt gcattttcaa tgattgtctt agcttcttta
    13501 cggctaccag ctaattcatc ttcgcgtttt tgagccaata cttctgcttt ttgacgggct
    13561 tcttcagctc tgtcaatatc tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta
    13621 atattagacc atgcaaattt tttaatcaag actagcaaaa gaataaaaga gccagtaatt
    13681 aaaacaaaat taccaattaa ttcacctact gttacgtgca tcagttactc ctttctattc
    13741 ctcttcaata ttaatcttat tccctaaata cacagatgtc aaaagagtaa aaacataagc
    13801 ttggatgcag gaaataaaga cagaaaatgc agtccaagcc aaattagctc caaaggctac
    13861 tggataccaa taaatagctt ggtgggaaag aagaagtaac aaactcgtca tgacctctcc
    13921 tgcaaagata ttcccaaaaa tccgcaaagc caaagataag aagtttgtaa attcttccaa
    13981 gatattcatc ggtatgacaa aaacaggact cataaaagat tttatacttt ttttaaatcc
    14041 acgacgacga acgctttcta tatgtgtcaa caaaatgaca agaaaagata aggttaagtc
    14101 atactgtaaa ttagcggttg gcgaactcca ccagttagtc ccatcgatcg tttgaagctt
    14161 tgtcattaag ccaaggttat tggcaatcac catgaaaagg aataaacaaa ggaaaaagag
    14221 tgagtaatct ttcatgtagc gcgaaccaat gttaggttct gtaaatccaa taacaaaatc
    14281 atagacatac tcaagtacat tttgctttcc tttgggtttc aaggtcatat tgcggcttgc
    14341 ccaataaata aagacaaaaa taactcccac aatcaacaaa gtcatggcta acatagtcag
    14401 attgaagata acaggaccaa tagagatgat tggattaata ctttcttcca tctaaaatcc
    14461 tcccttttct tctcgttcca tgtatttatt tgataataaa tgagaagaca agagttacaa
    14521 agaaagttcc ttcaataaag gcaacaccta aaaacatcaa actacgaaac tcagaaagca
    14581 tatctggttg gcgtgctact gatttaaaca gtccattcat caataaacct tcaccgacag
    14641 atacgcccat acaggcaata cataagccta aaaatgttaa attcataaca aattctcctt
    14701 taaaataaaa tttacttact tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg
    14761 ctattggaag cgtttaataa aaattatttc cattttgcta aatttcaagt tcaagttagc
    14821 catccagaag tcttctctgg gtgacttgta gtccaagcat tttttaggat agttgttaat
    14881 ccacttttcg atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca
    14941 tctacgaatg aacctgttgt gattctcatt agttcccctt tcccaagagg cataggggtg
    15001 cgcataataa atgtgctcct cagaaaatac atcagacaag cgattgaatt ccgttccatt
    15061 atctgccgtg atggaaagaa tcttgtgttg ttttaagatg agttttagag cctgattgac
    15121 cacctcagca cttttatttg gaatcaatcg gatgatctga tgtctactct ttcgatccgt
    15181 caagacaagc aagcagtagt ttttcgatct cgtaagtaga accgtatcaa tctcataatg
    15241 cccattctcc aagcgaagat tgatagcttc aggccgctgt gcgatggatt gaccagcagg
    15301 tttaaagttg gtgctagcct gtttcttaag cgcttttcct tttctagggt aaagcagatc
    15361 ctgcttgctt aaccccaatt ttccacgatg aatccaatag taaatggttg aaattcctac
    15421 gttaacccct ttagccatca ccatcatttc aggcgaaaat ttttggttat gatagtggag
    15481 aatcttttcc tttagttcct tggtcaagct tgatttcttg accgagcgct tgcgattgtt
    15541 ttcataagac tgttgagcat agtcggcaga ataaacctct ttgaagcacc cttttccaag
    15601 acattgtcgg actgtcccac gcttgatttc agtgtggata gtttgaggag cttttccaag
    15661 tagagaggca atttctctat ttgatttccc ttcttttttc catcgttcta ttaagcaacg
    15721 gctatcgatt gtcaaatgtt tgccttttgt agtataatag ttttgcatct ctgtgccttt
    15781 cttgtgtttg tggttgaaca acaagtatag cacagaggtg ttttcttatg cctacaagag
    15841 ctttcattat ttccactttc tttcggattt cactctattc tgaaaaactt gtgtatattt
    15901 actgaagcta gcaagtctta cctgtaaatt taatgaaagc aacacaaaat ccgagagggg
    15961 aatctcggat taatgtcaat ttaaaaagat agagagtttt tagtttaaat aaattgtttt
    16021 aaaatatcaa caacatcact tcttttctta acctgataag ccttaattcc taattttggg
    16081 gctacgatta tattgtcctc aatatcgtct agaaagacac aatttctagg ttataactgg
    16141 tatttatcaa tagttattca tatatatcag tccacctcca tactcacctt acagattctt
    16201 ttggtaataa tatctttgcc taatttagag atagtcttgc aaagaaaaaa cttccttgta
    16261 gccatgtttc tgataaaagt ccggtgcctg aaactggtaa gtattgacaa aggcaaaaca
    16321 acaatttcga ttcttagctt cactttctgc ctgttgcaat agttttgaac cgattccttg
    16381 ccctcgcagt tcctctttta caaacaaata ctcgatttct agccaatttc caaaagtctc
    16441 tgctatcaaa cctgccagga gattgccctt ttcatcttcg acataaagat taagtggctc
    16501 actttcagtc tcttctcttt ttgaacggtt ataaacacga agcagattcc ctatttcttg
    16561 cgatttatgt gattccttat tttccaatct aaagtatagt gaaatgaaat aaaacatgcg
    16621 caaatcgatt aaggaattta atctaatttc taacaatgtc ttagaaatca aagtgtacta
    16681 tgttaacttc aatgcactat acatctaata ctcaataaaa atcaaataat actcaataaa
    16741 aatcaaagag caaactagga aactagccgc aggttgctca aaacactgtt ttgaggttgt
    16801 agatgaaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg aaactga
//
LOCUS       DAVFJR010000047        15117 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVFJR010000047 DAVFJR010000000
VERSION     DAVFJR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.048"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(126..416)
                     /locus_tag="VU722_001868"
     CDS             complement(126..416)
                     /locus_tag="VU722_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772775.1"
                     /translation="MLEQIIQSLFIIVAIGLILLVLYQIAKILGSLFVIGLLGLLAFM
                     EIYGIYLFFTERYLYVEDLAANGILSFTTFYIGFNVLLIFGLVAKVIRSRMA"
     gene            complement(431..730)
                     /locus_tag="VU722_001869"
     CDS             complement(431..730)
                     /locus_tag="VU722_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772776.1"
                     /translation="MTQTVEEQRYQLEEWLAKGFTSPEDRANYQALKEQYEDETLDYS
                     FSKREIIGQLDIIITTRENNFPDLDEVTKESYIDLIAQLDDLDKGQANYYRKQLV"
     gene            complement(800..7603)
                     /locus_tag="VU722_001870"
     CDS             complement(800..7603)
                     /locus_tag="VU722_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU1772777.1"
                     /translation="MIQEQLLEMLRARLPRDQILLESFLRYQAVHFDEDWESLIQDFT
                     THRGVVPSPDQVVRFETEVSAFVKASPFDEATDLSSYTRTFGQAGLKKLPQLNSDEKA
                     LVIEVALFNLATRFQLLDQEGAYQSISVASLLEKGKAANLVNVYRVANNLSDRISRDI
                     EQFLLTYEPELDTRPIETISESDEIEVEPSPEITFREESFVIMASLEEDLSQLNLRTG
                     KTEHLPAYEHLNLSQKFEILSHFDQVRNSRPKLPNLRRGEFDHEMEMMPIYEEEELLI
                     YLEADGTIYDLQRPLTPQEEVILTEIGQTILAENTEKLTSLGIDLANFDENKQGVLID
                     ATGRFRLKNADLALLGGYPNASVTQLALTTELLQMGLTHDRAEFFLTSQLKLEDLRPI
                     AYAFLHEYLDIEEARTFERDKQSQPDVSFRDWRERLTQTESEIIMPQETPQNPIVEEA
                     LKRYPIDSTVSYKGEDLKVIAIEESGVNDLIRIELQNDFTDVIEQNPVLFLRTLEEIT
                     QALHLPSAEEKEEVKQPSQELDLFSFMLDDENQEDVFQEPVMEKEVEKSETLEEEIDS
                     ELFEVIEMTPTTDFHFPEDLTNFYPKTTRDKVETNVAAMRLVKALEAEERQATPDEQE
                     LLAKYVGWGGLANEFFDEYNPKFSKEREALKTLVTDKEYSDMKQSSLTAYYTDPALIR
                     QMWEKLEQDGFTGGKILDPSMGTGNFFAAMPKHLRENSELYGVELDTITGAIAKHLHP
                     NSHIEVKGFETVAFNENSFDLVISNVPFANIRIADSRYDKPYMIHDYFVKKSLDLVHD
                     GGQVAIISSTGTMDKRTENILQDIRETTDFLGGVRLPDTAFKAVAGTNVTTDMLFFQK
                     HVDKDYQAYDIAFSGAIRYDKDDRIWLNPYFDGEYNPQVLGTYEVRNFNGGTLSVKGN
                     PDNLIADVQIALKQVKAPRVVEPSDIFINSDVLARQVIDTSIPADIRESLEQYSFGYK
                     DSTVYYRDNKGIRVGTKTEEISYYVSEEGHFKAWDTKHSQKQIDRFNALEVTDSTALD
                     VYVTEEPAKRGRFKGYFKKTVFYEAPLSEKEVARIKGMVDIRNSYQEVIAIQRYYDYD
                     KDEFNHLLGKLNRRYDNFVKRFGYLNSPVNRNLFDSDDKYSLLASLEDEGLDPSGKTI
                     IYTKSLAFEKALVRPEKEVTEVSSALDALNSSLADGRGVDLDYMMSIYQTDSKASLIE
                     ELGDAIIPDPEPYLNDREVVYVSRQDFLLGDVVTKLEIVDLLIKEDNSDFPWVYYQGL
                     LEDVKPPRVTLADIDYRIGSRWIPLAVYGKFAQETFMGQTFDLTAPEVSTVLEVSPID
                     GTMSYQSKFAFRYSTATDRSLGVPGSRYDSGRKIFENLLNSNQPTITKQVEDGDKKKH
                     VTDVEKTTVLRAKETQLQELFQDFVASYPEVQQMIEETYNSFYNRTVSKVYDGSHLTI
                     DGLAQNISLRPHQKNAIQRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLY
                     VVPSSLTAQFGQEIMKFFPTKNVYVTTKKDFARAKRKQFVSRIITGDYDAIVIGDSQF
                     EKIPMSQEKQVAYIQDKLDQLREIKQGSDSDYTVKEAERSIKGLEHQLEELQKLERDT
                     FIEFENLGIDFLFVDEAHHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQVQGEHD
                     YRNVVFATGTPVSNSISELYTMMSYIQPDVLERYQVSNFDSWVGAFGNIENSMELAPT
                     GDKYQPKKRFKKFVNLPELMRIYKETADIQTSDMLDLPVPEAKVIAVESELTEAQKYY
                     LEELVDRSDAIKSGSVDPSEDNMLKITGEARKLAIDMRLIDPAYTLSDNQKILQVVDN
                     VERIYREGELDKATQMIFSDIGTPKSKEEGFDVYNELKDLLVDRGIAKEAIAFVHDAN
                     TDEKKNSLSRKVNSGEVRILMASTEKGGTGLNVQSRMKAVHHLDVPWRPSDIVQRNGR
                     LIRQGNMHQEVDIYHYITKGSFDNYLWQTQENKLKYITQIMTSKDPVRSAEDIDEQTM
                     TASDFKALATGNPYLKLKMELENELTVLDNQKRAFHRSKDEYRHTISYCEQNLPALEK
                     RLSQYDLDIAQSLATKSQDFVMRFDNQMMDNRAEAGDYLRKLITYNRSETKEVRTLAN
                     FRGFELKMATRSPSEPLPDMVSLTISGSNQYSVSLDLKSDVGTIQRITNAIDHILEDQ
                     EKTEKMANNLKDKLAVARVEVEKVFPKEEDYQLVKAKYDILAPLVEQEAEVEEIDAAL
                     AKFNETTQPKKDLQLSLDI"
     gene            complement(7655..8206)
                     /locus_tag="VU722_001871"
     CDS             complement(7655..8206)
                     /locus_tag="VU722_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772778.1"
                     /translation="MAWNYDTISKTLSEMAQENYEDMVKALLTMELSIKSKSLLDRLY
                     QDFMGIDDLSLVSDDLRLRADGYQEQLQEELTDLLDKLYRTGEGASFIMEVIASNNIF
                     DTLVQYEVLDEDDYSSLTLETLQDIIQKDLPLTSQDYFGDVTYLALQKDLLDQKSHFL
                     QQYVTTLVDKLPQEKDQSTLVLD"
     gene            complement(8190..8381)
                     /locus_tag="VU722_001872"
     CDS             complement(8190..8381)
                     /locus_tag="VU722_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HEU1772779.1"
                     /translation="MEPKSIYTMDSDQDGLTDAQELALGTNLFSSDTDSDGLTDLEEV
                     QQGLNPIQQGKESSYGLEL"
     gene            complement(8382..13286)
                     /locus_tag="VU722_001873"
     CDS             complement(8382..13286)
                     /locus_tag="VU722_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1772780.1"
                     /translation="MTKQCHHHFLVNQEQAEKHVFRKSKKYRTLCSVALGTMVTAVVA
                     WGGQVAQADEVTMPPLDKTVQLTENNATNLPEAQPAPVAEQTDSLASTGQSDGTITVT
                     VPHDTVTNAINQATAEGVTTVQDQPMDLGNTTSASDTSKQLDKAEADAAKQAEDITRV
                     TNTYKADKAAYEQDKTRVEKGNAALVASHKEATQAGKALNSSVDTTASEVQTQDKSAN
                     VTITTQTVPSGEGSTVSGYQDYTSAVAAIDKQNKASLADYITKKQAADAITAKNLAVQ
                     KENEAGLANAKAENEAITKRNQAEQKAIDDENKAGQAAVDTYNKNQQKLVTDREAEIA
                     AIIKRNKEKEEAAKKENEAIDAYNAKEMNRYKRDLADISKGEEGYISQALAQALNLNN
                     GEPQARHSADTRNPNRIIAKGDAMLGGYSKILDSTGFFVYDTFKTGETLSFTYQNLQN
                     VSFDGKKITKVAYDITNLVSPTETDSVQLVVPNDPTEGFIAYRNDGTGNWRTDKMEFR
                     VKAKYFLEDGSQVSFSKEKPGVFTHSSLNHNDIGLEYVKDTSGKFVPINGSTIQVTDE
                     GLARSLSSNRASDLNLPEEWDTSFSKYAYKGAIVSTVTSGNTYTVTFGQGDMPQNAGL
                     TYWFALNTLPVARTVKPYSPKPHVSPKLDPVPEPIKVVPKTFTPKTFTPEPPVIFKEK
                     PLEKVTQPRLTLTKVTFAKEPRSEPLPKAPQVPTVHYHDYRLTTTPEIMKKVVNTDQD
                     NLHDKTIAKDSTVIYPLTVDVFSSNRAKTTTLTFEDYLPAGYAFDKEKTQAENGNYTL
                     TFDEAKNFVTLTAKEALLQEVNQDLTKSYQLVAPKLYGSLQNDGATYSNSYKLLINKG
                     TSNAYTVTSNVVTVRTPGDGKITSRITPQKRNENEDGVVINDTVVALGTTNHYRLTWD
                     LDQYKGDTSSKETIARGFFFVDDYPEEVLDLVDKGTSITTLDGKAVSGITVKAYASLS
                     EAPKDLQDKLAHAKISPKGAFRIFQPNDNQAFYDQYVKTGTSLNLLTKMTVKDSLYGQ
                     TKTYRNKAYQVDFGNGYKTNEVTNTLVSPTPKKQNLNKDKVDINGKPMVVGSQNYYTL
                     SWDLDQYRGIKADKAQIAKGFYFVDDYPEEAVLPDDTAIQLTTSNGKAVIGVTVKNYT
                     SLSEAPKPLQASFEKRKIAPKGAFQVFMAEDPQAFYDSYVTKGQNITIVTPMTVREEM
                     LNSGKSYDNVAYQVDFGQAYETNTVTNHVPKVNPHKTNTNKEGVSIDGKTVLPNTVNY
                     YKIVLDYSQYKDLVVTEDTLAKGFYMVDDYPEEALTLNADGVQVMDKAGNLVKGISVK
                     AYASISEAPQVVQEAMAKRQLTPKGAIQVLSADDPKAFYETYVKTGQTLVVTLPMTIK
                     NELTKTGGKYENTAYQIDFSLAYVTETVVNNVPKLDPQKDVVIDLSQKENSLDGKEVA
                     LNQVFNYRLVGALIPGNRATPLIEYRFDDDYDESHDDYNGVYKAYTVVDVTLKDGTVL
                     LKGTEVTKYTLQHVDTSQGTVTISFDKEFLEKLAEESEFQADVYLQIKRIASGEVENT
                     VLHTVNGYTISSNTVKTTTPEPEPPTPNQPTPPQPLIPTQEPPVPASVLPNTGESQSL
                     LALVGGGLLLGLAYVLAKRKMEDN"
     gene            13480..14070
                     /locus_tag="VU722_001874"
     CDS             13480..14070
                     /locus_tag="VU722_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEU1772781.1"
                     /translation="MSKKELLLEYINNHNGLITHRDCKKLGIPTIYLTRLEDEGVIFR
                     VEKGIYLSSSGDYDEYYFFQYRYPRTVFSYISSLYLQGLTDEIPQYFEVTVPKDYRFR
                     NRPLNLNSYTVSKDIINMGVTSVKTPMGNTVNVYNFERVLCDFILNRSNIDNELFVKT
                     VQTYSNFPEKNLAKLYDYAQKLNILDDVKRTLEVLL"
     gene            14067..14912
                     /locus_tag="VU722_001875"
     CDS             14067..14912
                     /locus_tag="VU722_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEU1772782.1"
                     /translation="MNKAKLTALCHNISKQTGLTFNSVMTYYFLEVILKKLSRSSYAD
                     HYIFKGGFLLSNIIGVESRSTVDIDFLFHKQTLSEENVQQQLEEILSEVKNDIQFSIQ
                     SITTIKESDDYGGYRATILCQLENIKQIIHLDIATGDVVTPQPITYDYKAIFNDENFP
                     IIAYTIETVLAEKLQTIYSRSFLNSRSKDFYDIYILSKLKKDDIDLAQLKMACEKTFS
                     YRETELNFNNIIQLLETFKSDSTQQQQWQNYSKKYSYTKGISFSEILDEMIRLVSLLI
                     SLNNE"
BASE COUNT         4093 a         3210 c         2975 g         4839 t
ORIGIN      
        1 ataggaaatc gaacgacgga gcgactactc ctagggagat ttatcttttt ccacagagtt
       61 gtaggcaagt tcagttttca agatacaaat cattagaaga gtctgggaca atagtctcca
      121 ttattttatg ccatccgact tctaataacc tttgccacaa gtccgaatat aagtagcaca
      181 ttaaatccaa tatagaaagt ggtaaaactc aaaataccat tggccgctaa atcttcgaca
      241 taaaggtatc gctctgtgaa aaagagataa atgccataga tttccataaa ggctaggagg
      301 ccaagcagtc cgataacaaa cagacttcct aatattttcg caatctgata gaggacgagc
      361 aaaatcagcc ctattgctac gataatgaaa agactttgaa tgatttgttc taacatatct
      421 acgcctcttt ctacactaat tgcttacggt aatagttagc ctgcccctta tctaggtcat
      481 caagttgagc aattaagtca atatagcttt ctttggtcac ctcatctaag tctggaaaat
      541 tattttcacg agtggtaata atgatatcta attgaccaat gatttctcgc tttgaaaagc
      601 tgtaatcaag ggtttcatct tcatattgtt cctttaaggc ttggtagtta gctcggtctt
      661 cagggcttgt aaaacctttt gctagccatt cttctagttg gtatctttgt tcttctactg
      721 tttgggtcat gttctgttct cctttggtga tttcttaatg tcattttacc gcgttcaaaa
      781 ctatttgtca gcctttttat taaatatcaa gagaaagttg aaggtctttt ttcggttggg
      841 tcgtttcatt aaatttagct agtgctgcat caatttcctc aacctctgct tcttgttcta
      901 ccaagggagc taatatgtca tacttagctt taaccagctg ataatcctct tctttaggaa
      961 aaaccttctc tacttcaacc cttgcgactg ctagcttatc ttttagatta ttggccattt
     1021 tttctgtttt ttcttggtcc tctaggatat ggtcaatggc attagtaatg cgttggatgg
     1081 ttcccacatc tgatttcaag tctaaagaga cagaatactg gttgctacct gaaatggtta
     1141 aagacaccat atctggcaac ggctcactag gacttctggt tgccatttta agctcaaatc
     1201 ctctaaaatt agccagtgtt ctcacttctt tggtttcaga acggttatag gtaatgagtt
     1261 ttcgtagata gtctccagct tctgcacggt tatccatcat ttgattgtca aaccgcatga
     1321 caaaatcttg tgacttagtt gccaaagatt gagcaatatc aaggtcatat tgactgaggc
     1381 gtttctcaag ggcagggagg ttctgctcac agtaagaaat ggtatggcga tactcatctt
     1441 tggagcgatg aaaggcacgc ttttgattgt ccaataccgt caactcattc tctagttcca
     1501 tcttgagttt cagataagga ttacctgtcg ctaaagcctt aaagtctgaa gcggtcatgg
     1561 tttgttcatc aatgtcttct gccgaccgta ctgggtcttt agaggtcatg atttgcgtga
     1621 tgtatttgag tttattctcc tgagtttgcc agaggtagtt atcaaatgac cctttggtaa
     1681 tataatgata gatatctacc tcttggtgca tattgccttg acgaattaac ctaccattgc
     1741 gttggacaat atcagaggga cgccagggaa catctaaatg gtggactgct ttcatacgtg
     1801 actgtacatt taatcctgtt ccaccttttt ccgtagaagc catgagaatc ctgacttccc
     1861 cactattgac cttgcgtgag agagagtttt tcttctcatc cgtattagcg tcatgaacaa
     1921 aggcaattgc ttctttggca atccctctat ccactaagag gtctttcaat tcattgtaaa
     1981 catcaaaccc ttcttcttta cttttaggcg ttccaatatc agagaaaatc atctgggtag
     2041 ccttatcaag ctcaccctca cggtaaatgc gttccacatt gtccaccact tgaagaatct
     2101 tctgattgtc cgataaggta taggctgggt caatgagacg catgtcaata gctagttttc
     2161 tagcttcccc agttatcttt aacatattat cctcactagg gtcaacgcta cctgacttaa
     2221 tggcgtctga acggtcaacc aactcttcaa ggtagtattt ctgagcttct gtgagttcac
     2281 tctccaccgc aatgactttg gcttcaggta caggtaaatc aagcatatct gaggtctgaa
     2341 tatcagctgt ttccttataa atccgcatga gttcaggcag gttcacaaac ttcttaaagc
     2401 gtttcttagg ttggtactta tctcctgttg gggcaagttc catagaattc tcaatattcc
     2461 caaaagctcc cacccatgag tcaaagtttg agacttgata gcgttctaag acatctggtt
     2521 ggatataact catcatggta tagagttcac taatagagtt agagactggt gttcctgtcg
     2581 caaagaccac attacgatag tcgtgttctc cttgaacctg tctcactttc atttccatat
     2641 ccacattctt tttagaggtc gtgttggtaa ttcctgcgac attaccaagt ccagtaatgg
     2701 ggcgaatatt cttaaaatga tgagcttcgt ccacaaagag aaagtcaatc ccaaggtttt
     2761 caaactcaat aaaggtatct cgctccagtt tttggagttc ttccaattgg tgctccaacc
     2821 ccttgataga acgctctgct tctttaaccg tatagtcact atcactgcct tgtttaatct
     2881 ctcgtaattg gtccagctta tcttggatat aggcgacctg cttttcctga ctcatgggga
     2941 ttttctcaaa ctgggaatcc ccaatgacaa tggcatcgta gtcccctgtg atgatccgtg
     3001 agacaaactg cttacgtttg gctctcgcaa aatctttctt ggtcgtcacg taaacattct
     3061 tggttgggaa gaacttcatg atttcttggc caaactgagc ggtcagactt gatggcacca
     3121 cataaagagg cttatgcacc atacccaatt ctttcagttt gaatcctgcc ccaagcatgg
     3181 ttaaggtctt acctgaaccc acttcatgag ctagaagcgc tcgtttttct tccacaatgc
     3241 gttgaatagc attcttctgg tgagggcgaa gagaaatgtt ttgtgctagc ccatcaatgg
     3301 ttaaatggct gccatcataa acttttgaga ctgtacgatt ataaaagcta ttataggtct
     3361 cttcaatcat ctgttgcacc tctgggtaac tagccacaaa atcttggaag agttcttgaa
     3421 gttgtgtttc cttagcacga agaaccgttg tcttctccac gtccgtcaca tgctttttct
     3481 tatccccatc ttccacttgt ttggtaatgg ttggttgatt ggaattaagc aggttttcaa
     3541 agattttgcg accactatca tagcgtgacc caggaacacc taaacttcta tccgttgcgg
     3601 ttgaatatct aaaggcaaac ttagattggt aggacattgt gccatcaatc ggactaactt
     3661 caagaacagt tgatacctct ggggcggtca ggtcaaaagt ttgtcccata aaggtttctt
     3721 gggcaaattt cccataaacg gctagaggaa tccatcgtga gccaatccga taatcaatat
     3781 cagctaaagt cacacgtggt ggtttcacgt cttctaagag accttgataa tagacccaag
     3841 gaaaatcaga attgtcttct ttaatgagta agtccactat ctctagctta gtcactacat
     3901 ctcctaataa gaaatcctgc cgcgacacat ataccacttc cctatcgttt agatagggtt
     3961 ctgggtctgg aataatagcg tctcccaatt cctcaatcaa agacgctttg gaatccgtct
     4021 gataaataga catcatataa tccaaatcca ccccacgacc atctgcgagg ctggaattga
     4081 gagcatcaag ggcagaagac acctctgtta cttccttttc gggacgaacc aaggcttttt
     4141 caaaggcaag tgacttggtg taaatgatag tcttaccact tgggtcaagt ccttcatctt
     4201 ctagactagc aaggagcgaa tacttatcgt cactatcaaa tagattacgg ttcacaggac
     4261 tattcaaata tccaaatcgt ttaacaaagt tatcatatct gcgattgagt tttcctagca
     4321 agtgattaaa ctcgtctttg tcgtaatcat agtagcgttg aatggcaatc acctcttggt
     4381 agctatttcg aatatcgacc atccctttaa ttcgtgccac ttctttctca gacaaaggag
     4441 cctcataaaa gacggtcttt ttgaaatacc ccttaaatcg gccacgcttt gcaggttctt
     4501 ctgtcacata aacatcaaga gctgtgctat cagtcacctc taaggcatta aagcggtcaa
     4561 tctgcttttg agaatgcttg gtatcccatg ccttaaagtg accctcctcg ctcacatagt
     4621 agctgatttc ttcagtctta gtccctacac ggattccctt gttatctcga tagtaaactg
     4681 tggaatcctt ataaccaaaa ctatactgtt ctaaactctc tctgatatca gctggaatcg
     4741 aggtatcaat gacttgtctt gccagtacgt ctgaattgat gaaaatgtca gaaggttcaa
     4801 caactctagg cgctttaacc tgtttaagag caatctgaac atctgcaatc aagttatcag
     4861 gattgccttt aacagaaagg gtgcctccat taaagtttct cacctcataa gttccaagaa
     4921 cttgaggatt gtactccccg tcaaagtaag gattcagcca aatacggtca tccttgtcat
     4981 aacgaatagc acctgaaaag gcaatgtcat aagcttgata atccttgtcc acatgtttct
     5041 ggaagaacaa catatccgtt gtgacattgg tacctgcaac ggccttaaaa gccgtatctg
     5101 gcaaacgcac accaccaaga aaatcagttg tttcgcgaat gtcctggagg atattttctg
     5161 tccgtttgtc catggttcca gtggaggaaa tgatagccac ttgaccacca tcatgcacca
     5221 aatcaagcga ttttttaaca aaataatcat gaatcatata gggcttatca taacgactat
     5281 cggcaatcct gatattggca aacggcacat ttgagatgac caaatcaaag ctattctcat
     5341 taaaggcaac ggtctcaaag cccttcactt caatgtgact atttggatgg aggtgcttgg
     5401 caatagctcc tgtaatcgtg tctaattcca caccatacaa ctcactattt tctctcaggt
     5461 gtttaggcat agccgcaaag aagtttcctg tgcccatcga agggtctagg attttacctc
     5521 ctgtaaagcc atcctgctcc aacttctccc acatctgacg gataagagca gggtctgtgt
     5581 aataggcagt caaagaggat tgtttcatgt ccgaatactc tttatctgtg actagcgttt
     5641 ttaatgcctc acgttcctta gaaaatttag gattatactc gtcaaagaac tcattagcaa
     5701 gccctcccca gcccacatat ttagcaagga gttcttgttc atcaggcgtg gcttgtcgtt
     5761 cttcagcttc aagagctttt acaagacgca tggcagccac gttcgtttca accttatctc
     5821 ttgttgtctt agggtaaaag tttgtcagat cttctgggaa gtgaaaatca gtggttggtg
     5881 tcatctcaat gacttcaaaa agctctgaat caatctcttc ttcaagagtt tcagattttt
     5941 ccacttcttt ttccatgact ggttcttgaa aaacgtcttc ttggttctca tcgtctagca
     6001 taaaggaaaa gaggtctaat tcttggctag gttgtttcac ttcttctttt tcctcggcag
     6061 aaggaagatg gagagcctga gtgatctcct ctaatgtccg taagaaaaga actggatttt
     6121 gttcaatcac atctgtaaaa tcattttgta gttcaatccg aatcaggtca ttgacacctg
     6181 actcttctat ggcaatcacc tttaagtcct cccccttata ggacaccgtg gaatcaatcg
     6241 gataacgttt aagggcttcc tctacaatag gattttgagg tgtttcttga ggcatgataa
     6301 tttcagattc tgtttgtgtt aggcgctctc gccagtctct aaaggatacg tctggctggg
     6361 actgtttgtc cctttcaaag gttctagctt cttcaatatc gaggtattca tgtaagaaag
     6421 cataggcaat cggtcttaag tcttctaact ttaactgact ggtcaagaag aactctgccc
     6481 tgtcatgcgt tagtcccatc tgaagcaatt ctgttgtaag agctaattga gtgacggatg
     6541 cgttaggata gccccctaat aaggctaagt ctgcattctt caaacggaaa cgccctgtgg
     6601 catctatcag taccccttgt ttattctcat caaagttagc taagtctatc cctaaactgg
     6661 tcagtttctc agtattctct gctaaaatcg tttgaccaat ttcagttaag atcacttctt
     6721 cttgcggtgt taggggacgt tgtaagtcgt aaatcgtccc atctgcttct aaatagatta
     6781 atagctcttc ttcctcatag ataggcatca tttccatctc atgatcaaac tctccacgtc
     6841 ttagatttgg cagttttgga cgactatttc tcacttggtc aaaatgactc aatatctcaa
     6901 acttctgaga caagtttaga tgttcatagg ctggtaaatg ttctgttttc cctgttcgca
     6961 aattgagttg cgagaggtct tcttcaagac tcgccatgat gacaaaactc tcttcacgaa
     7021 aggtaatttc tggactgggt tctacttcta tttcgtcact ctcggagata gtctcaatag
     7081 gtctggtatc cagctccggt tcataagtta agagaaattg ttcaatgtca cggctaatac
     7141 gatcagataa gttgttagcg actcggtaga cgttgaccaa gttagcagct ttgccttttt
     7201 ccaaaagaga agctaccgaa atagactgat aagctccctc ttggtctaat agctgaaagc
     7261 gagtagctag gttaaagagg gctacctcaa tcaccaaggc tttctcatcg ctgtttaact
     7321 gaggtaactt ctttaggcct gcttggccaa aggtccgcgt atagctactg aggtctgtcg
     7381 cttcgtcaaa agggctcgcc ttcacaaaag cagaaacttc tgtttcaaag cgaaccactt
     7441 gatcaggtga ggggactact cctctatggg ttgtaaaatc ttggataagg ctctcccaat
     7501 cttcatcaaa atgaactgct tgatagcgta aaaaggattc taaaagaatc tggtcacgtg
     7561 gcaatcttgc ccgcaacatc tcgagtaact gctcttgaat catacgttcc tccaaatcaa
     7621 aaaaggagct gagaggtagt ctcagcccac tgctttagtc taggactaag gtgctttggt
     7681 ctttttcttg tggcaactta tccactaaag tcgtcacata ctgttgtaag aaatggcttt
     7741 tctggtctaa caaatctttc tgcaaggcaa gataggtcac atctccaaaa taatcttgac
     7801 tagtgagagg caagtccttt tggataatat cttgcaaggt ttctaaggtg agcgatgaat
     7861 aatcgtcctc atccaaaacc tcatattgaa caagggtatc aaaaatatta ttagacgcta
     7921 tcacttccat aatgaaacta gctccctctc ctgttcgata gagtttatct aacaaatccg
     7981 tgagttcttc ttgaagctgt tcctgataac cgtctgctct taggcgcagg tcatcactga
     8041 ctaaagacaa gtcatcaatg cccataaagt cttgatagag cctgtcaaga agtgacttgc
     8101 ttttgatact caattccatg gttaataagg ctttgaccat atcttcatag ttttcttgtg
     8161 ccatctcaga gagagttttt gaaatcgtgt cataattcca agccataact gctctcctta
     8221 ccttgttgaa ttggattcaa gccttgttgg acttcttcaa ggtctgtcag tccatcacta
     8281 tccgtatcac tgctaaaaag attggtccct agagctaact cctgagcatc cgttaagcca
     8341 tcttggtctg aatccattgt gtaaatgctt ttaggttcca tttaattgtc ctccattttg
     8401 cgtttagcaa ggacgtaggc taagcctaaa agaagtcctc caccgacaag cgccaaaaga
     8461 gattgactct ctcctgtatt tggtaagaca cttgctggaa ctggtggttc ttgtgttgga
     8521 ataagtggtt ggggtggtgt tggttgattc ggagttggtg gctctggttc aggagtagtt
     8581 gttttaaccg tgtttgaact gatggtgtag ccattgacgg tatgtagtac cgtattttct
     8641 acttcacctg aagcgattcg ttttatctgc aagtaaacat ctgcctgaaa ctcggattct
     8701 tctgctagtt tttctaggaa ttccttgtca aaactgatgg taaccgttcc ttgtgacgtg
     8761 tcgacatgtt gtagcgtgta cttagtcact tctgtccctt ttagtaaaac cgtcccatct
     8821 tttagagtga catctaccac agtataagcc ttgtaaacac cattatagtc gtcatggctt
     8881 tcatcgtaat catcgtcaaa gcggtattcg atgagtggtg tcgcacgatt accaggaata
     8941 agtgctccca ccaagcggta gttaaagacc tgattcaagg caacttcttt tccatcaaga
     9001 ctgttctcct tttgtgacaa atcaatcacc acatcttttt gtgggtctag ttttggaaca
     9061 ttattgacca ctgtttctgt cacataagcc aaactaaagt caatctgata agccgtgttt
     9121 tcatacttgc caccagtctt tgtcaactca ttcttaatgg tcatcggaag cgtcaccacc
     9181 aaggtttgac ctgtcttaac ataggtctcg taaaaagctt ttggatcatc agcacttaaa
     9241 acttgaatgg ctccttttgg tgtaagttgg cgtttggcca tagcttcttg caccacttga
     9301 ggcgcttctg atatcgaagc ataggctttg acagaaatcc ctttgacaag atttcccgcc
     9361 ttatccatca cttgaacacc gtctgcattt agtgttagag cttcttctgg atagtcatct
     9421 accatgtaaa aacctttggc aagggtatcc tccgtcacta ccaagtcctt gtactgacta
     9481 taatccagaa caatcttata gtaatttacg gtattaggaa gaacggtttt gccatcaata
     9541 gacactccct ctttattggt attggtctta tgaggattta cctttggcac gtgattggtc
     9601 accgtattgg tttcataggc ttgcccaaag tctacttggt aagccacgtt atcataagac
     9661 ttccctgaat taagcatctc ctcacgaact gtcatcggtg taacgatggt aatgttttgg
     9721 cctttggtca cataagaatc ataaaaggct tgtggatctt ctgccataaa gacttggaaa
     9781 gctcctttag gcgcaatctt gcgtttctca aaggatgctt gtaggggttt aggggcttct
     9841 gataaactcg tgtagttttt taccgtaaca cctatgacag ccttgccgtt agatgtcgtt
     9901 agttgaatag ctgtgtcatc tggtagcaca gcttcttcag gatagtcatc cacaaagtag
     9961 aagccttttg cgatttgagc tttatcagct ttaatgccac ggtattggtc taaatcccat
    10021 gacaaggtat agtagttttg tgaacccact accatcggtt ttccattgat gtccacttta
    10081 tccttattaa ggttttgttt cttaggtgtg gggctgacaa gggtattggt cacctcattt
    10141 gttttatagc cattcccaaa atcaacttgg taggctttgt ttcgataagt cttagtttga
    10201 ccataaaggc tgtctttgac ggtcattttg gtgagaaggt tcaaagaggt tcctgtttta
    10261 acgtactggt catagaaagc ctgattgtcg ttaggctgga agattcggaa agctccttta
    10321 ggagaaatct tggcatgagc gagtttatct tgaaggtctt taggagcttc tgacagcgac
    10381 gcataggcct taacagtaat ccctgatacg gctttaccat caagagtggt gatacttgtt
    10441 cctttatcca ccaaatccaa gacttcttct gggtaatcat ccacaaagaa gaaaccacga
    10501 gcaatcgttt ctttagaaga ggtatcacct ttatattgat ctaaatccca cgtcaaacgg
    10561 taatggttag tcgttcctaa agccaccacc gtatcgttaa tgaccacacc gtcttcattc
    10621 tcattgcgtt tttgaggagt aatacggcta gtgattttcc catcaccagg tgtacgaacg
    10681 gtcaccacgt tagaggtcac tgtataggca tttgacgttc ccttattgat gaggagctta
    10741 taactattgg aataggtagc cccatcattt tgaaggctac cataaagttt aggagccacc
    10801 agttgataag acttagtgag gtcttgattg acctcttgaa gcaaggcttc tttggcagtc
    10861 agggtcacaa agttcttagc ttcatcaaag gtaagcgtat aattcccatt ttctgcttgt
    10921 gttttttctt tatcaaaggc atagcctgct ggaaggtaat cttcaaacgt aagggtagtt
    10981 gttttggcac gatttgaaga aaaaacgtca actgttaaag gataaataac tgtcgaatcc
    11041 ttggcgatag ttttgtcatg aagattgtct tggtcggtat tgaccacttt tttcatgatt
    11101 tcaggggtcg ttgtcagacg atagtcgtga taatgaaccg ttggtacttg tggtgcttta
    11161 ggcaaaggtt cagacctagg ttctttagca aaggtcacct ttgtcaaagt caagcgaggt
    11221 tgagtcactt tctccagtgg tttttcctta aagatcacag gtggctctgg ggtaaaggtc
    11281 tttggggtaa aagtttttgg cacgacttta atcggctctg ggactgggtc tagttttggg
    11341 ctcacatgtg gtttcggact ataaggtttg acggttcgtg caacaggtaa ggtgtttaag
    11401 gcaaaccaat aggtcagtcc tgcattctgg ggcatatcgc cttgtccaaa agtcacggtg
    11461 taggtattgc ctgatgtgac ggttgagaca atcgctccct tgtaagcata cttgctaaaa
    11521 gaggtatccc attcttctgg gaggttcaaa tcactagcac ggtttgaaga aagtgaacgt
    11581 gctaggcctt catctgtcac ttgaatggtt gagccattga tagggacaaa cttgcctgat
    11641 gtgtctttga catactctaa gccaatgtca ttatgattaa gtgaggaatg ggtaaagaca
    11701 cctggttttt ccttgctaaa gctgacttgc gagccatcct ctaagaaata cttggctttg
    11761 acacgaaact ccattttatc ggttcgccaa ttccctgtcc catcattacg ataggcaata
    11821 aagccttctg ttgggtcatt aggcacaact aattgtacag aatccgtctc agttggagac
    11881 actaggtttg tgatgtcata agcgactttg gtaatctttt taccatcaaa actcacattt
    11941 tgaaggtttt gataagtgaa tgaaagggtt tctccagttt taaaggtatc atagacgaag
    12001 aaaccagtag aatctaggat tttagaatac ccaccaagca tggcgtcacc cttagcaatg
    12061 atgcgattag gatttctcgt gtcagctgaa tgtcgggctt gcggttcccc attgttcaag
    12121 ttgagagcct gagcaagagc ttgtgagatg taaccttcct ctccttttga gatgtcagct
    12181 aagtcacgtt tgtatcggtt catttctttg gcattgtagg catcaatggc ttcattttct
    12241 ttcttagcag cttcttcttt ctccttattg cgttttataa tagcagcaat ctcagcttca
    12301 cggtctgtca ccaatttttg ttggttctta ttgtaggtat ccacagcagc ttgacctgct
    12361 ttattttcat catcaatcgc tttttgttct gcttgattgc gtttagtaat cgcttcattc
    12421 tctgcctttg cattcgcaag acctgcttca ttttcctttt gaacagctag gttctttgcg
    12481 gtaatggcat ctgcggcttg ttttttcgtg atatagtccg caagactagc cttgttttgt
    12541 ttatcaatag cagctaccgc agatgtgtag tcctgataac ctgaaacagt tgatccctct
    12601 cctgacggaa cggtttgagt tgtaatagtc acgttcgcag acttgtcctg agtctgcact
    12661 tctgaagccg tggtatctac tgaactattc aaggcctttc ctgcttgagt agcttcttta
    12721 tgactagcaa ccaacgcagc attccctttt tcgacacgag ttttatcttg ttcataagcg
    12781 gctttgtcag ctttataggt atttgtcacc cgagtgatgt cctcagcttg tttggcagca
    12841 tccgcttccg ctttatctaa ttgcttactg gtatcactcg cagaggttgt gtttcctaaa
    12901 tccatcggct ggtcttgaac agtagttacc ccttcagcag ttgcttgatt gatggcattg
    12961 gttaccgtat catgaggaac cgttactgtg atagtcccat ctgattgacc ggttgacgca
    13021 aggctatcag tctgttcagc aactggtgct ggctgagctt ctggtaaatt ggtcgcatta
    13081 ttttccgtta actgaacagt cttatctagt ggtggcattg tcacttcgtc agcctgggct
    13141 acttgcccac cccaagcgac aacagctgtc accatagttc caagtgctac cgaacacagc
    13201 gtacggtact tcttactttt acggaagaca tgcttttctg cttgttcctg attgactaaa
    13261 aagtgatgat gacattgttt ggtcataaaa agtccttctt ttcttttgat aagtagcaac
    13321 aatctgtcac tctctcctca tcataaaaaa gacgacttga ttttggtatc acatcacata
    13381 agagactagt aaatgctaat taataacacc caaaatgttg cttctgcacc gttaaaatgc
    13441 taaaattaaa gtacaaaagc aacaaagaaa ggagagatta tgtctaaaaa agaattgtta
    13501 cttgagtaca taaacaatca caatggtctg attacccata gagattgtaa aaaattaggt
    13561 attccaacca tctatctaac gagactagaa gacgaaggag ttatctttag ggtcgaaaaa
    13621 ggtatctatc tatcttctag tggagattat gatgaatact atttcttcca atatcgttat
    13681 cctagaactg tcttttctta tatctcttct ctttatctac agggacttac tgatgaaatt
    13741 cctcaatatt ttgaagtaac agttcccaag gactatcgtt ttagaaacag accattgaat
    13801 ctaaatagct acactgtttc taaagatatt attaacatgg gggttaccag tgtcaaaaca
    13861 cctatgggaa atacggttaa cgtttataat tttgaacgtg tactatgcga ttttatcctt
    13921 aatcgaagta acattgataa tgagctcttt gttaaaacag ttcaaactta tagtaacttc
    13981 cctgaaaaaa atcttgcaaa actttatgac tatgctcaaa aattaaatat cttagatgat
    14041 gttaaacgaa ccttggaggt actcttatga ataaagcaaa attaacagca ctctgccata
    14101 acatttctaa acagaccggc ctaactttta actcagtaat gacctactac tttcttgaag
    14161 tcattttgaa aaagctaagt cgaagttctt atgcagacca ttatattttt aagggaggat
    14221 ttttgctttc aaatatcata ggagttgaat ctcgtagcac ggtggatatt gattttctct
    14281 ttcataaaca aacactatca gaagaaaatg ttcaacaaca actggaagaa attttaagtg
    14341 aagtaaaaaa cgatattcaa ttttcaattc aatccattac aacgattaaa gaaagcgatg
    14401 attacggtgg ttaccgagca accattttgt gtcaactgga aaacattaaa caaattatcc
    14461 atttagatat tgcgactgga gatgttgtta cacctcagcc cattacctac gattacaaag
    14521 ctatttttaa tgatgagaat ttccccatca ttgcttatac aattgaaacg gtgctagctg
    14581 aaaaattaca aaccatttac tcaaggagct tcttaaacag tcgtagcaaa gatttttacg
    14641 atatctatat cctttcaaag ttaaagaaag acgacattga tttggcacaa ttaaagatgg
    14701 cttgtgaaaa aaccttctct tatcgtgaaa ctgaactcaa ttttaataac atcattcaac
    14761 tgcttgaaac cttcaaatct gactctactc agcagcaaca atggcaaaat tattcaaaaa
    14821 aatatagtta tacaaaaggg atttcctttt cagaaatcct tgatgagatg attcgtttag
    14881 tcagtctttt aatctcttta aacaatgaat aaaacaactt ttcggttatc ttttaaccga
    14941 tacagacaac attaaaagga tatgcgagca actccttacc ttgttcgcat atcctttttc
    15001 ttatttcatc gtatacgcaa aactaatcgt accatctact cctgataact tacggaaggt
    15061 gtaattggga ttaccattgt agttggtctc tgagatgagg aacgatccat ctgggta
//
LOCUS       DAVFJR010000048        13960 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVFJR010000048 DAVFJR010000000
VERSION     DAVFJR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.049"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            91..161
                     /locus_tag="VU722_001876"
     tRNA            91..161
                     /locus_tag="VU722_001876"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:123..125,aa:Cys,seq:gca)
     gene            complement(359..1690)
                     /locus_tag="VU722_001877"
     CDS             complement(359..1690)
                     /locus_tag="VU722_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU1772783.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VU722_001878"
     CDS             complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VU722_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU1772784.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(2844..3032)
                     /locus_tag="VU722_001879"
     CDS             complement(2844..3032)
                     /locus_tag="VU722_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU1772785.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VU722_001880"
     CDS             complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VU722_001880"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU1772786.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASERETVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(4332..4562)
                     /locus_tag="VU722_001881"
     CDS             complement(4332..4562)
                     /locus_tag="VU722_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU1772787.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(4620..5657)
                     /locus_tag="VU722_001882"
     CDS             complement(4620..5657)
                     /locus_tag="VU722_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU1772788.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMVYAWLTPFTDIRSVQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPALRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGGAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VU722_001883"
     CDS             complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VU722_001883"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU1772789.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VU722_001884"
     CDS             complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VU722_001884"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU1772790.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(6723..7715)
                     /locus_tag="VU722_001885"
     CDS             complement(6723..7715)
                     /locus_tag="VU722_001885"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU1772791.1"
                     /translation="MKKSFIHQQEEISFVKNTLTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(7826..8509)
                     /locus_tag="VU722_001886"
     CDS             complement(7826..8509)
                     /locus_tag="VU722_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU1772792.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFFASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(8565..9305)
                     /locus_tag="VU722_001887"
     CDS             complement(8565..9305)
                     /locus_tag="VU722_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU1772793.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            9339..9617
                     /locus_tag="VU722_001888"
     CDS             9339..9617
                     /locus_tag="VU722_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU1772794.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            9695..10621
                     /gene="yidC"
                     /locus_tag="VU722_001889"
     CDS             9695..10621
                     /gene="yidC"
                     /locus_tag="VU722_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU1772795.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFASQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIINYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VU722_001890"
     CDS             complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VU722_001890"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU1772796.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(11604..12866)
                     /locus_tag="VU722_001891"
     CDS             complement(11604..12866)
                     /locus_tag="VU722_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU1772797.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYTRELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKKTYRTYLGVDASAINLMRPAMYGAYHHITNLTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     VRQIRRAERPKDYFATLYGFDFEEESEK"
     gene            complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VU722_001892"
     CDS             complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VU722_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU1772798.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQVIDVEVGNIFDEDK"
BASE COUNT         4074 a         3273 c         2594 g         4019 t
ORIGIN      
        1 ttggcatcac attcgaatca cgctatggta caaaaaactg aaaaaactat tgactgaaaa
       61 tcattttcaa ggtataataa taaacgttaa ggcggtatag ccaagtggta aggcacggct
      121 ctgcaaaagc ttgatcgtcg gttcaaatcc gtctaccgcc ttctataact tgatttatca
      181 ggtttcaaat gaacagaaag cccaatttga agggcttttt ttattttccc tcgaataaat
      241 acgtataact ttaaaaactt ttggagcgag tttgtggcag agttctttcc atggcataat
      301 tcccttttga aatcaattga aaaaagcttc gtcacgcctg gtgacaaaag cctctagttt
      361 attctgtttc ttcttctatt tcgacttctg tgatttggac ttttaccttg gtaacacgtc
      421 cattcttcac tttatcattg gttaagataa actgtttgtt ttggctgacc aattcatagc
      481 tgagtttctc agtcgttgga atggttccca ctcctgtcaa ataataacca gcgatggtat
      541 caacgtcatc actttccagt tcaacatcaa agtaattatt gaaatcattg agggtcatag
      601 ttccttgaac aatgtaggta tcctcgccaa tctgatgaac atctattgct gctttgtccg
      661 tttcatcatc aatttcacca acaatttcct ctaagaggtc ttccaaagtc accaaaccag
      721 ccataccacc gtattcatcc agcaagattg ccatttgtct ttgggtattt cgcagttctt
      781 ttagcaagtc atccacaaaa atagtttcag gtacaaaaag tggatcttgt aaaattctct
      841 tccaaacaat attgtcaaaa ccgtccacaa agcctgcctt aaggagactc ttggtgtgaa
      901 tgattccaat tacattgtcc ttatccccat cataaaccgg gatacgagaa taattttgtt
      961 ttaaaatact ttggataatg gcttgactat catcctgaat atccaccata aaggcatccg
     1021 ttcgaggaac cataacctct cgtgccatca gttcatcgag cgaaaagaca ccttgtagca
     1081 tctcaatctc atcagcatcc aatgtttctt cactatttgt caacatatag gcaatttcat
     1141 cacgggtcat cttttcatcc gcatcatcga atgacatagg agtcaaatgg ctcaagaaat
     1201 tggtcgaagc agctaaaagc caaacaaaag gactgactag ttttccgatc ccaatgataa
     1261 tcggcgctgt acgaattgcc aaggcatcct ttagattaag agcgattctc ttaggatata
     1321 attccccaaa aacgatggaa atataggtca aaaatgccaa ggatagaaaa gttgccacgg
     1381 cttgtgctgt ttcgccattc ccaagccaag aggcaatcac acgtcctaga gtatcagtta
     1441 aactcgcccc tgataagatt gtaatcaggg tgattcctac ctgaatggtt gataaaaagt
     1501 ggttaggatt ttctagtacc ttcagcaggc ggatgtagcg tctgtctcct tcttccgcct
     1561 tttgttcaac tcgggcacga ttaagagaaa ccatggccat ttctgtggct gagaaaaagg
     1621 catttaatac cgtcaagata aacaataaaa caaattgtag caacaaattc tgactacttg
     1681 ggtcttccat agttcttctc ctaaaatagt atcttatcct ttattatatc acaaaattta
     1741 atccaataca tattattttt ttcttagcgt aacttccatc tctctcccaa aactggaagt
     1801 tagtctaaga cggatttcca ctgatttcac gcgtttttct catactaaaa gctaggttgt
     1861 gggaaactgg aagttagttt tagaagttac cattttttct tagtacctat tctagccctg
     1921 cttaaactag taaaaagaac tcctacatcc ataagtgaca taggagttta ggcttatctt
     1981 ttactgagtt acagttactt ctccagttcg gtaatccagt tgaagtccct tttgaacatt
     2041 gggaactaga acattgaatt ccaattctcc atccgaagac ttggcttcaa tctgtgaagc
     2101 tgagggaact aaatcctcgt ttgaagcgta gtaaagggtt acacggtaac ggacacgctt
     2161 gttttggtcc aaggctttac gcaccttgct ttcatagtag ttttgaccag tcgaatcctc
     2221 ggcttgtgcc tgatttgccc aggctgtttg aacagcaatg tttttaggat tgcttgtcga
     2281 ggcatcaaaa ccatccaagc caccgattaa ggcatagcct aacaagtgac ctctatcgac
     2341 cgcatgggta taagtcccct ttagattctt gacctgatgc caacctggag gagtccaaga
     2401 agttgaacca ttcccagttt cttcacgatt cttgtactga cgagtggcct tagacaaaag
     2461 ggcattagct acggttggaa cagtttcctt gcccactgtc tttgttttat tgtcagcgta
     2521 gggcttactt gaaaccttgg catctagatt tgttttatta ccattgacga taaaagcacc
     2581 tgagccattc cactccagac tcccctttat ttgactcttg actgcgtctg ttaagacact
     2641 ttctgccaat tcttgactag gagcttcagg cgcttgtttt ttctgactaa gattggtttt
     2701 gggactatta ggtgccgact gcatctgctt gatataatag ctccctgtag acaaaagcaa
     2761 taacactagc agtccgatta gtgtctgtct tgtttttttg ttcatatttc tccttatctt
     2821 tagaaaaagg ctggttctcc agcctaattt cctgtaaatt tatgaatcaa ttcctgccat
     2881 tttgccggag acaggatagc ccacggatct tgacccttgc ccaagattcc atagcctacc
     2941 attaaaccga ttcctaaggc tagaaggcct aaaatcagta ccagaatgac taaaagtaaa
     3001 cgcttgatta cgtaacctga tttcttattc atcttcatca cttgcctcaa tccgctgaat
     3061 cttagcacct agctgcgcca acttctcatg gaaaccgtag taacctctat ccaagtgaac
     3121 caatttaccg accacagttt ctccctgtgc taccaaacct gtcaaaatca aagctgcact
     3181 ggcacgaagg tcagttgaaa gaacttctgc tccctgcaaa ggctgtccac caacaatacg
     3241 agctgtatca cggataatct cagaatgcaa gcccatgcgg cgcatctctt ctaggtgttg
     3301 gaaacgattt tcgaaaactg tctccaccat ggttgattcg ccttttgcaa ctgtcatcaa
     3361 ggctgtaaat tgagcctgca tatctgttgg aaatcctggg tggggcaagg ttttcacatg
     3421 aacagctttt agattttcta gttgagaacg aacacgaatt ccttcgtctt cttcaattac
     3481 ttcaacaccc atttcaagta acttggcaat caagggacgg ttgtgctccc agacagcgtc
     3541 tcgaatcaag acatcaccac cagtcatggc agcagctacc ataaaggttc ctgcttcgat
     3601 acgatcttgg actacattgt gagtcgtacc atgaagtttc tcaacaccag taatggttat
     3661 agtctctgta ccagcacctt tgaccttggc tcccatttca ttaaggagaa tggctaagtc
     3721 aacaatctca ggctcacgcg cagcattctc aatcactgtc accccatcag ccagagtcgc
     3781 tgccatcatc aagttctgcg ttgcaccaac acttggaaag tccatataga tatgagcgcc
     3841 atgcaagcgt tctgccttgg cttctatgta accagctgtc tgactaatct taacccccat
     3901 agcttccaga cctttcaaat gaagatcaat aggacggcta ccaatcgtac aaccacctgg
     3961 catggatacc ttggcatgac ccacacgggc aaggattggc cctaatacaa cgatggaggc
     4021 gcgcatcttg ctgacatact tgtaaggggc ttcctcagtg atgtcgccag tagcatccac
     4081 cttgacaaga tgagcttcct catcaaagtc aaccttggca ttcaaaccac caactacctg
     4141 attcataata aagacatccg acaaaatcgg aacattctgc aagacggtct ctctttcact
     4201 tgctagaata gtcgctgcca acaagggtaa gactgcattt tttgctccct cgatcgtcac
     4261 gcttcctacc agacgattat cgccaccttg aaccacaatt ttatccatac tcgtttcctt
     4321 tactcttgat tttataataa tcctctaagc gcttcttgcc acaaatgata caggctaata
     4381 aagaaagaac tcaggatgta gcctatgaca atgctaaaaa aggctactaa taaacgaact
     4441 tttcttgtat tatcatctgt cacttttaaa accttctccc atctaacaag atcctttaaa
     4501 aggtaaaaac tcacataaat aaagagcata tgactactta gagtgaataa taattgaacc
     4561 atttgactat tataccatct tctctgtttg tgcgctagtt tggaaacttc actcaaaaat
     4621 tagggattgt ttttcaagta atcaatcgca tcttgtaggg ttttaacggg cacgattttc
     4681 atatccgtct tgattgtttt agccgcttct agggctgttt ggtagttgtt tttcgcgtcc
     4741 ggatgcgcct tttgttcttc ttcgctaaca gggttatcag gagcaaagaa aatagcacca
     4801 cctgccctag ccgaagctac aaccttctta tcaatacctc caatgtctcc cacattacca
     4861 tcgcggtcaa tggtacctgt accggcaaca atacgaccat tacgaagagc tgggtgagct
     4921 atttgagtat agatagctag actaaacatg agaccagcac ttgggccgcc aataccagct
     4981 gttgaaaagc taattgggac attgctgatt acctctgtac gatcaatcaa gccgattcca
     5041 atcccatttt ttccattttc caaggtgata atctttcctt ctgcagactt ggtttgccca
     5101 tcctcttcat aggtgacctt gacggagtcc cctaattttt gagaactgac gtaatcaatc
     5161 aagtctttgg aactatcaaa ggtctgatca ttgactgctg tgaccgtatc agagatattg
     5221 agaatccctt taaaggttga attatccgtc acattcaaga cataaacccc aaagtacttg
     5281 agttcgatat ccttaccagc tgtttttaga ccttgatact tggccatatt ttgtgatgtt
     5341 tgcatgtaga attgattgat tcgcataaat tctacatcgg aagaaccacc tgtggtctcc
     5401 tgaacactac gaatatctgt aaaaggcgtc aaccaagcat aaaccatatg agctaatgtg
     5461 gcatgttgaa caccaaccgt aacgaattga taggcaccag cttccttatc ttctgtgtca
     5521 tttactttaa ggacttggcg aatatcttcc gaaccacctg gaacctctat ataataaggc
     5581 aagggcacta caaatgccaa gaaagtcaca atcaaggccg caatgacgta taagggccat
     5641 ctaatctttt ttttcatttc ttatttcctc caaaatactc tcgggaacat agcaggcaat
     5701 atcctgacca aacttcaaaa gctctctaac gcctgatgaa ctgatataga gatgttcagg
     5761 tcgactatgt aaataaatag tctctatatc agaagacagc tgatgattgt agtaatcaaa
     5821 actggcttca tattgcaaat ccgacgcatt cctcaaacca cgcactagac aagtagcacc
     5881 caatcttttt gcaacatcga ccaccaattc atcatgagaa gccacgactt caacattttc
     5941 caaatgtccc aaagcctttt ctagcccccg tttacgattt tcaagaggga gaaatccttg
     6001 tttgtgggga ttaaaaaaaa tacccacaca aagcttatca aaaagtctgc tcgcccgttc
     6061 aatgatatcc agatgcccat ttgtcatcgg atcaaatgag cctgtgaata agccaatctt
     6121 atctgacata gactgtcacc ttactaattc cataaatctt ttccttccag atacccagac
     6181 aggcaatctc ttctggaagt tcaacggcct tatccgtctc gcacacaacc ataacatctt
     6241 cagaaaaaag ctctctctca gccatttttt caatatctgc tacgatttgt tccttggcat
     6301 agggagggtc taagaaaacg aggtcaaatt ccccagatac ctgttccaat gccctctctg
     6361 catccatctt gaggagttga aattttccaa cttccttggt catctggata ttttcagcca
     6421 cgatggtctg agccttacgg tctcgctcca ccaaaacagc actggacatg ccacgcgata
     6481 ctgcttcgat agataaacca ccactacctg cataaaggtc caagactcgt cccccttcaa
     6541 agtagggacc aatcatgtta aaaatggctc ccctaacctt atccgaagta ggtcttgttg
     6601 tcttgccttc tagtgtcttg aggggacgtc ccccatagat tcctgatacg attttcatac
     6661 tgtttattgt accaaattat agacaaaaag agaaagaaaa ccgaaccttg cggttcgatt
     6721 ctctacaaaa tattttcgta agtatcgcgg acttcttgag gccaaacact tgtttgcact
     6781 tctccgatgt gtctcttgcg aagtaggaac atggccatac gagattgtcc aattcctcca
     6841 ccgattgtca atgggaatag gccattcaac aaagacttgt gccattccaa ttccaagcgg
     6901 tcttcatcac ctgtaatttc cacctggcgt ctaagagttt cttcatctac acgaattccc
     6961 atagaagaca actcaaaggc tccacctaaa gactcattcc agacaagaat atcaccattt
     7021 agacccttgt agccattctc agactcgctt gtccagtcat catagtctgg tgcacgtcca
     7081 tcgtgcggtt taccatctgg caactcgcca ccgataccaa tcaaaaagac ggctccaaat
     7141 tctttacaaa tcgcattttc acgttctttc ggtgtcaagt ctgggtagcg ttctaccaat
     7201 tcttctgtat ggataaaggt gatttgtttt ggcaagatag actcgatgtc atagcgagct
     7261 tcaacagcta gctcagtcag gcgaatagcc ttataaatct tctcaactgt ttcttttaga
     7321 taaacgatgt tacgcttacc atttgggata accttctccc agtcccactg gtcaacataa
     7381 acagagtggg ttgcatccaa ggaatcctca tctggacgaa gggctttcat gtggacaaag
     7441 agaccctctc cttcaccaaa gccaaaacga gccaaggtgt ggcgtttcca tttagcaagt
     7501 gagtgcacca cttcataagt agcatcaggg atttggagaa ccttgaccga tactggattt
     7561 tccacaccag acaggttgtc ctgcattccg tcaccgacct tactcaagat aggaccttga
     7621 acttcgacaa cttctagctt atctttcaaa tactgggtca aagtgttttt gacaaaggaa
     7681 atttcttctt gttgatggat aaaacttttc ttcatagaca actcctcaaa aatttaataa
     7741 acgtattata cacctatttc caagaaaaga aaagagaaaa tttaaaaaaa tcagtgtcac
     7801 tcaaaacact gatttcatag accttttagt cattgcgacc aaagatacgt agaatactta
     7861 ggaaaagatt gataaaatca agatagatgc tgagagccat tgacaccacc cagcctgtcg
     7921 ctacacgacc ttgtgattgt tcataggcga ggcgaatctt ttggttatcc caagcaatca
     7981 accctgaaaa aaccaaaacc atggctacgc taatcatata atcaaagaag ccactagcaa
     8041 agaaaatatt gactaccata gcaatcagta aaccaatgag agctgccatc attgctcgac
     8101 caatcccact caagtctttc ttggtaaaga taccaactgc cgccatgaca aagaagagaa
     8161 gggcgctcga tacaaaggca gataaaactg tacccggagt atagaaagcc accacaaaac
     8221 taagggtaaa gccgtttaaa acggagtaaa gtaaaaatac tggaagagca gctggactat
     8281 ttcttgaagc catgctactg gcaacgaaaa ccaaagccaa ctccgcaaaa gtagcaatgg
     8341 tcaaccagag acgcccctgc atcaaaaagt aaaccaactg agactgaaag accgtcaaca
     8401 taaggcctga taccaaagca gatagtccga ttcccagacc aacaaaggca taaaccttag
     8461 cgtaaaattg attgagacct gcacggtcat gtataatagt gtgattcatc catttctcct
     8521 tttctgtgaa catctttcct tgattataac aaaaaaagtt aaaattagct taaatggaag
     8581 attaaaatac cggctgcaac cgcaacattc aaactctcgg cctgcccctt catgctaata
     8641 tggaccaact ggtctgcact ttcagccata aggggactaa ttccttgacc ctcatttccc
     8701 ataactagta caaaattttc tatagaaggc agttctctgt aatcaacaga atctttagat
     8761 agggttgttg ctagcactgg gatagctacc tttttagttt cgtcaagaag cgcttgacta
     8821 gtcatccggt aaatgggcag atggaaatga ctaccttgca tggaacgtag ggttttgaga
     8881 ctgtagatgt ctgccgactt atctgaaaca atcactcctg taaaacctgc tgcatccgca
     8941 gttcgaatga tagttcctac attaccagga tcttgcacat cttccaaaaa caagaacttg
     9001 ccctgactca aatcagcttg tcctacttct tctctttgaa ccacggcaac aattccctgt
     9061 ggagtctgag aatccgccaa atctagcaaa atatcctctg acacccagac agtttgcgaa
     9121 aaagtagcta actgatctcg ataattttct agggtaaaga ttttctcaat cgtcactcca
     9181 gcttgaacag cttcttcaaa caagtgccag ccttcaatta aataggcaga cttgcggtat
     9241 tttttttggt gtaatttctt ggtatttttt acaacagaat tggcttttga ggttataata
     9301 gtcatagaaa tattataaca caatcaaagg ggtttggtat gcaaaaggtt agaatgattg
     9361 cccaaggtag ggtgcaggga gtcggctttc gttggggtgt ttatagcctg gcccttgaaa
     9421 tcggtggcat cacaggtcgg gtatggaata acgacgatgg cacagtggaa atcttagccc
     9481 aagcagactc atctgctatc atggcaaaat ttatccaaga aatccgaaaa ggaccgacac
     9541 ctttttcaaa agtcagttac ttagatgtca aactgagcaa ctttcctccc taccctgact
     9601 ttaaaatcgc aaattaggtc tccagaacta ttgtatattt tgtaaaaaaa cagtagaata
     9661 gaaaggtata atttttaaag aaggaataaa aacagtgaaa tctattaaac gttttgcatt
     9721 ctcggctatg ggagtggcta tgttgcttgt cttgactggc tgtgtcaatg tcgataaaac
     9781 cacaggtcag ccaacaggat ttatttggaa tacgatcgga gcgcctatgg ctgaagccat
     9841 caagtacttc gctactgata aaggtctagg ctttggtgtc gctatcatta tcgtaaccat
     9901 tatcgtacgc ttgattatct taccacttgg tatctaccaa tcatggaagg caacgcttca
     9961 ctctgaaaag atgaacgctc tcaagcatgt ccttgagcca caccaaacac gtctcaaaga
    10021 agcaactact caagaagaaa aactcgaagc ccaacaagcc ctctttgccg ctcaaaaaga
    10081 gcacggcatc agcatgtttg gtggtgtagg atgtttccct atcctccttc aaatgccttt
    10141 cttctctgct atctactttg cttcccaaca tactgaaggg gttgctcaag caagctacct
    10201 aggcattcct ctaggttctc caagtatgat tttggttgcc tgtgctggtg tcctttacta
    10261 tcttcaatcg ctcctttcac ttcacggagt agaagatgaa atgcaaagag aacaaatcaa
    10321 gaaaatgatt tacatgagcc cactcatgat cgtcgtcttc tccctcttct caccagctag
    10381 tgtcacactt tactgggttg tcggtggttt catgatgatt ctccaacagt ttatcatcaa
    10441 ctatatcgtt cgtccaaaac ttcgcaaaaa agtccgtgaa gaactagcca agaacccacc
    10501 aaaagcaagt gctttctcta aaccaagtgg acgaaaagac gttacccctg aacaaccaac
    10561 tgctatcaca agcaagaaaa aacacaaaaa tcgcaacgct ggaaaacaac gttcgagata
    10621 agaagaaaaa ggcttagctg atttgctaag tctttttgca aatcaaaagc ccgatgtttc
    10681 catcaggctt cttttctatc catgtacacg tttcatataa tcttgataac tttcggtatc
    10741 catgagtttt ttagcgttct tgacgcgatc tgctgttggt ggtttgactc cttcgaggga
    10801 atatggaatt ccaagttcac gccacttgaa ctcacccatg gtgtgataag gtagaatttc
    10861 aaacttatca acatttttga gggtcttgac gaacttacca agttcaatca agtcatcatc
    10921 tctgtctgtc aatcctggaa ctagcacatg gcgaatccag acaggttttc caatatctga
    10981 tagatactgg gcacaagcca agatattttt attggtttgg ctagtgacaa tcttgtgctg
    11041 ttcttcgttg atttccttga tatccaaaag aaccaagtca gtgacagcca tgagtttgtc
    11101 aaacttctca aggtaacgtg gtttattacg gaaaggaaga gcacaggtgt ccaaggtaca
    11161 gtggattcct tgttccttag ccttggtgaa gagggcaatc aggaaatcaa tctgcaagag
    11221 agcttctcct ccactgactg taatcccacc cttatttccc cagaaaccac ggtagcgcaa
    11281 ggcctctgtc aagacatcat ctaccgtccg ttcacgtgac ttattggact ccatagccca
    11341 agtgtctggg ttgtggcaat actggcaacg catgtgacag ccctgcaaaa aaacaataaa
    11401 gcgaatacca ggcccatcta ctgacccaaa gctttctgtc gaatgcacca ttcctgtcac
    11461 ttgtccataa tcaattgttt cttcagacat atcgttacct tccttgaaaa cgttttatag
    11521 ttttattata tcacgacttg aaggaaaaac aaggtttttg cctatttttt agaaagcaat
    11581 ctgtttttca atttcatttt caattacttc tcagattctt cttcaaaatc aaagccatac
    11641 aaggttgcaa agtagtcctt aggacgctct gcacggcgga tttgacggac tttgccttct
    11701 tcagtataga ggatttccgc agaacgaagt ttggcattgt actggtaacc cattgaaaat
    11761 ccatgggcac ctgtatcatg aatgaccagc aaatcaccga tttctgtatg aggcagttcg
    11821 cgattcactg caaatttatc attgttttca cagagtgaac cgaccacatc taccacttca
    11881 gctggtccat ctggatgtgt cagattggta atatgatggt aggctccata catggctgga
    11941 cgcataaggt tgattgctga tgcatccaca cctagatagg tacggtaggt tttcttctta
    12001 tgagtgactc ttgtgaccaa agctccgtga ggtgccagca taaaacgacc caactcagta
    12061 aaaatcttaa cctgaccaag acctgctggc gtaaggacct cttcatacac cttacgaact
    12121 ccctcaccaa tcaaggcaat atcgttcggc tcctggtctg gacgataatt aacaccaata
    12181 ccgccagaaa gattgataaa gtctaacgaa atgcccaact tttccttgat ttcaacagcc
    12241 agttcaaaga gctgacgagc caactctgga taatagagat gggtcacggt attggacgct
    12301 aggaaggagt gaagcccaaa agtcttggct cctttttcct tcaagatagc aaaggcttca
    12361 aagagctggt ccttggtcat gccaaactta gcctccccag gattgtccat aatgtctgtc
    12421 cccagttcaa aaacgcctcc aggattataa cgacaagaga tgatttctgg aatgcctgct
    12481 gctctctcca gatgttcaat atcttcaaag gcatccaagt taatggtcgc acccaattca
    12541 cgtgtatagg cgtattcctt gtctggcgtg ttgttggaag agaacataat ctcagaaccc
    12601 agaaagtcca gtttatggct catcaaaagc tctacataac tagagcagtc cacaccacaa
    12661 ccttcttctt ggagaatttt caaaatagct ggagttggag tagccttaac tgcaaaatat
    12721 tccttaaagc ccttgttcca cgaaaaggct tggttgacgg ctcttgcctt ctcacgaatc
    12781 cccttctcat catacaagtg aaagggagtc gggaactcgg caacaatcgc ttctaactct
    12841 tctctattaa taaatggtgt tttcataagc ttccttctat tctgtttgca aagaaaggct
    12901 gggacaatcg ttccaacctt tagttctatc tcttatttat cttcgtcaaa gatattgcca
    12961 acctcaacat cgatgacttg gttcttgaca tcaatattgg ttaccttcaa gagtgacttg
    13021 tagtcaaact gcttttcacg ttcttcttgg gcattgtccg caaagaccgc tacacctgcc
    13081 agttctgagt cgaactcgcg caagagacta atcatcccgt tgacagttcc gccacctttc
    13141 aagaagtcat ccacaatcaa gacacggctg cctgccttga gactgcgttt tgaaaggaac
    13201 attttctcga tacggtcacc acttgaacct gaaacatagt tgacgctaac agttgaacct
    13261 tcggtaattt tcaggtcacg gcgcacaatg acaaaagaga cattgaggac attggcaact
    13321 gcatttgcaa gtggcacacc cttagttgct acggtcataa ccgcgtcaat tttttggtcc
    13381 ataaagcttt tggcaataat acgaccaata tttttcaaga tggctggtgt gctaagcaaa
    13441 tcagacagat agatataacc acctggcaag atacggtcac tttctgacaa cttggtacgc
    13501 aagtcttcaa ccatttcctt agcatcctga ctcgaaatag acggtgtgaa gatgacacct
    13561 ccgccagccc cagtcactgt ctggatatga ccgatttcaa tttcctcaaa ggcgcgtttg
    13621 ataatgacga tatcttctga gatggatgat ttagcagact catacttttc agcaaaagta
    13681 ttgagactag ttagtttata aggattatta atcaaatagt tggaaatgac aaccatccga
    13741 tcacttcttc ttaatttcat ttctatttcc tattccattt ttattcaaaa aatcaaaaag
    13801 caaactagaa agctggtcgc tggtggttca aaacactgct ttgagattgt cgatagaact
    13861 gacaaaccct gtaatatacc tgcatatata catacgacaa ggcgatacta ccctagtttg
    13921 aagagatttt cgaagagtat tcatttttgt cttttactta
//
LOCUS       DAVFJR010000049        13929 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVFJR010000049 DAVFJR010000000
VERSION     DAVFJR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.050"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(51..680)
                     /gene="nth"
                     /locus_tag="VU722_001893"
     CDS             complement(51..680)
                     /gene="nth"
                     /locus_tag="VU722_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU1772799.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(680..1222)
                     /locus_tag="VU722_001894"
     CDS             complement(680..1222)
                     /locus_tag="VU722_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU1772800.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1392..1709
                     /locus_tag="VU722_001895"
     CDS             1392..1709
                     /locus_tag="VU722_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU1772801.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            1948..2256
                     /locus_tag="VU722_001896"
     CDS             1948..2256
                     /locus_tag="VU722_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1772802.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKLYTTTSF
                     "
     gene            2304..3506
                     /locus_tag="VU722_001897"
     CDS             2304..3506
                     /locus_tag="VU722_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1772803.1"
                     /translation="MHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPS
                     NDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHL
                     DYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLA
                     KKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDD
                     RVLAQELRLTVRGQEKIGIIGPNGVGKSTLLAKLKQFLNDKREISLGFMPQDYHKKLQ
                     LDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLR
                     KPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTEHGL
                     ELVNLEDV"
     gene            complement(3550..4449)
                     /gene="htpX"
                     /locus_tag="VU722_001898"
     CDS             complement(3550..4449)
                     /gene="htpX"
                     /locus_tag="VU722_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU1772804.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(4451..5011)
                     /locus_tag="VU722_001899"
     CDS             complement(4451..5011)
                     /locus_tag="VU722_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU1772805.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPNNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            5105..5818
                     /gene="rsmG"
                     /locus_tag="VU722_001900"
     CDS             5105..5818
                     /gene="rsmG"
                     /locus_tag="VU722_001900"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU1772806.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFECYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            6170..7453
                     /locus_tag="VU722_001901"
     CDS             6170..7453
                     /locus_tag="VU722_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU1772807.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(7648..9219)
                     /gene="ffh"
                     /locus_tag="VU722_001902"
     CDS             complement(7648..9219)
                     /gene="ffh"
                     /locus_tag="VU722_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU1772808.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHQVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPI
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSAPGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9231..9563)
                     /locus_tag="VU722_001903"
     CDS             complement(9231..9563)
                     /locus_tag="VU722_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU1772809.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(9654..10031)
                     /locus_tag="VU722_001904"
     CDS             complement(9654..10031)
                     /locus_tag="VU722_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU1772810.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGNYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            10103..11407
                     /locus_tag="VU722_001905"
     CDS             10103..11407
                     /locus_tag="VU722_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU1772811.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            11420..12226
                     /gene="yidA"
                     /locus_tag="VU722_001906"
     CDS             11420..12226
                     /gene="yidA"
                     /locus_tag="VU722_001906"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU1772812.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLADLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(12437..13744)
                     /locus_tag="VU722_001907"
     CDS             complement(12437..13744)
                     /locus_tag="VU722_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772813.1"
                     /translation="MLVDFINNSQRQYSFINADGISVEDITDEKNLKFYFYGPVKGEI
                     FRYQEKHDLFLYYRDPLTSVEVPVENTIKVVEMYEETDLIIKVGDYIFQDVKRHRFPD
                     GSVELHFGDCFKMSFDVNKKIFKFNYTRSNMLSKAIECTEVLQELGRVGYFNLNGNKI
                     ELDKQSISDITSQNLDSDIKDLKQISNILKNIGVQKDLDLNCFDKQSQKNLNILNSGL
                     VLKEKVALDYNESKLLHLRIANIHIITLYDYAIDKNGFMINIFTETPWCRRGEDEGGL
                     DISIFEPNYWLKIDNCDFDSVIASYQRLVDNQLRYEGTNNTIIKIVVAADKAEDVSRS
                     ELLLNWAQCLSDWNLKYSKNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYE
                     LCFGSSVLLKSKPQADLFWNKLDNETKERYKDFPIYTLYMKLS"
BASE COUNT         4198 a         3032 c         2493 g         4206 t
ORIGIN      
        1 tatagcacaa agcatgctta aaatcaagca aaaagtttca atgtagcatc ttacaaattg
       61 ctaaaatcat ataattgtgg gtactggtca cactctggat tttttggatg gcaaatggct
      121 cttccaaaat aaatcatggc ctgatgggca gctaaccact gctcaggcgg caagatatcc
      181 atgacccgct tttccacctc aagtggcgtc gctgattttt tgacaatatc gtggtgtttg
      241 caaatacgct ccacatgagt atccactgca aaggctggaa tcccaaatcc tacactcatg
      301 acaacattgg ctgtcttgcg accaacacct gccaaactct ccaattcttc acgtgtctga
      361 gggacttgac catcaaaatc gtctagtaac tgttgggcac attttttaag gaatttagct
      421 ttattccgat acaatcccaa gcgagaaata tgtgaagcaa tctcactctc tgtcgctaca
      481 gacatagctt ggggtgttgg aaaggcaaca aagagacctg gtgtggcctt atttaccgct
      541 gcatctgtcg tctgggctga taacatgacc gcaaccagga gttcaaaatg attggtaaaa
      601 tcaagactag gcttggcatc tgggaagagg gcaatgattt cttctagcac ctttcgtgct
      661 cgtttttttg acaagaccat tattcatctc cgtcaaatag tccttgtaag ccagcaaaag
      721 gactgttttc ttctttcttt actgcttgtt gagcttggta ttcttcctct gtcatgattt
      781 gccagtcatt tcctgagaca aatccttgac cagcttcttc ttcagccgtc aagaccttga
      841 taggaatgtt tagcaggata ttgtctgata cactctcagc aaggtcaagc gccccatttt
      901 cgatgggcaa gaccaagtca tcatctaaaa cttcttgatc tagctggtta gttgcgcctt
      961 ccatgaaaac ttccgtgact ggataagatt caactaactc aactggctcc atactgcgac
     1021 tcgaagcaag aacaatggta taagatagtt gataatctaa gaaatacata cggtcttcat
     1081 attgtacttt cccaactgca aggatatctt ttacatctaa aatttcttga ttacgtgcac
     1141 gcaggtcacc aactaaatct aacgtttgtt caaagttcaa accttcagac tgcttacgaa
     1201 tttcttgaat atttaatttc atacttcctc cataaagatt tactctcttg attataccat
     1261 gaaaaggcta caaatcagca caccaaactt tgtaattaaa attcaaaatt ttaacatatt
     1321 tactatgaca gttttgtttt ttagtgctat actataggga aagagtacat cagatcaagg
     1381 aggatgctca catggaagac aagaaactca ttcaactcct atccaagtta aataaaagct
     1441 accaaaactg taaacagggt acggcagatg atattcgact acaagagctg ctaaacacta
     1501 ctatgcaaga gctcaaaaaa acggaaaagt tgaacaacag tatcttaatt gatcttgaga
     1561 aattttacca acccaccagt cttctgattg gactgggtag cctaaaacta aacgatcaag
     1621 cacgcactgc ttggcgaaac tatgataaat tccattacga gcatgtcaaa cacgtactaa
     1681 gtctctatgg acctgttttt ggattttaga gcatagaatt tccagttttc tgttgacaaa
     1741 atttccttaa aggtataata taaagatact aatactcgga ggtaagggag acatgaacaa
     1801 ctaagtctat caaataaaga acctttattt agtagatctt gtttttgtct ctttttgtgt
     1861 gctcttttat gctctttttc tggcatgtta atagagtttt tttgacatag actttgggat
     1921 ctactaggta aagtagagct ttttgttatg cactatgaac attctagaaa gggaaatcat
     1981 atgataaaaa tcaatcacct gaccatcaca caaaacaaag atttacgaga ccttgtctct
     2041 gacctaagca tgaccataca agacggggaa aaggtagcta ttattggcga agaaggaaat
     2101 ggtaaatcaa ccttacttaa aactttaatg ggggaagatt tgtctgattt cactatcaag
     2161 ggagacatcc agtctgatta tcagtcactg gcctacattc ctcaaaaagt ccctgaggac
     2221 ctaaaaaaaa aactttacac gactacttct ttttagattc tattgattta gactacagta
     2281 tcctctatcg tttggcggag gaattgcatt ttgatagcaa tcgtttcgca agtgaccaag
     2341 agattggcaa tctatcaggg ggcgaagctt tgaaaattca gcttatccat gagttagcca
     2401 aaccctttga gattctattt ttagatgaac cttcaaatga cctagacctt gagacagttg
     2461 attggctaaa aggccagatt caaaagacca ggcaaaccgt tattttcatt tcccatgatg
     2521 aagactttct ttctgaaacg gcagacacta ttgtccactt gcgactggtc aaacaccgta
     2581 aagaagcgga aacgctagta gagcatttag actatgatag ctatagtgag cagagaaagg
     2641 ctaattttgc caaacaaagt cagcaagctg ctaacaacca aagagcctac gataaaacca
     2701 tggaaaaaca tcggagagtt aagcaaaatg tagaaactgc gcttcgagct accaaagata
     2761 gtactgccgg tcgcctattg gctaaaaaga tgaaaactgt cctctcacaa gaaaaacgct
     2821 acgaaaaggc agctcagtcc atgactcaaa agccacttga agaggaacaa atccaacttt
     2881 tcttttcaga catccaacca ttaccagctt ctaaagtctt agtccaactg gaaaaagaaa
     2941 atttgtccat tgacgaccgt gttttggctc aggaactgcg actaactgtc cgtgggcaag
     3001 aaaaaatcgg tattatcgga ccaaatggtg ttgggaaatc aactctgtta gccaaattaa
     3061 agcaatttct gaatgataaa agagagattt cccttggttt tatgccacaa gattaccaca
     3121 aaaaactgca attggattta tcctcaatag cttatatcag caaaactggg gaaaaagagg
     3181 aacttcagaa aatccaatct cacctagcca gtctcaattt cagttatcca gaaatgcagc
     3241 atcaaattcg ctccttatct ggcggacaac agggaaaact cctgcttttg gatttagtcc
     3301 tgcgcaaacc aaactttctc ctgctggatg aacccacacg aaacttttct cccacttctc
     3361 aaccccaaat cagaaaactc tttgcaacct atccaggcgg tctcatcact gtttcgcatg
     3421 accgtcgttt cttaaaagag gtctgttcaa gcatctaccg cttgacagaa cacggtttgg
     3481 agttagttaa tttagaagat gtataaattt gcaacatagc aaaaatccag agacgacctc
     3541 tggattcttt tacatctgtt ttaaacgttc aatccgttct gagataggtg ggtgggtata
     3601 aaagagtttt tggaaccccc cacctttctt gggatcattg atataaaggg cactgctagc
     3661 atcatcgacg tggcgactca taggtttgct attgtccaac ttatctaggg cattaatcat
     3721 tccctgggga ttgcgagtca gctcgacact agatgcatct gccagaaatt ccctctgacg
     3781 agaaatagcg agctgaacca aggttgcagc gagaggtgcc agtacaatag ctagtaggga
     3841 aaccactagc ataatgattt caagaccatt tccatctcgg tcatcatcac ttcgtctgcg
     3901 acctgctcca ccccaccaca tcatacgacc tgccatacta gaaagcatgg tgatagcact
     3961 agcaagggca actgcaatag tcgaaatacg gatatcataa ttacgaatat gactaacttc
     4021 atgtcccata acagcttcta gttcttcacg attcatgata gctagtagac ctgaagtcgc
     4081 agcaacagcc gcattttgag gattagaacc tgtcgcaaag gcatttaagg ctggatcatc
     4141 aatgatgaaa acacggggca taggaatctg agcgaccaga gccatatctt ccactacatg
     4201 gtagaggtct ggtgccgttt gctcatccac ctcacgcgct ccattcatgg acatgacaat
     4261 ctctgtcgat tgaaaaatca tagacaaagc gtagataaag ccgataatca gtgcgataac
     4321 caaaccacca agtccagatc ttataaagag ataaccaacc gcataaccaa caagagctaa
     4381 gagtaggaaa aataccagca acaaaatcca ggtttttcgt ttattgcttg caatttgatc
     4441 aaacaacatc ttagtcacct aaaccgctaa aatcaacttt aggaaccgac ttttcctctt
     4501 caggtgtttg aaggaaatct gccgctttaa atccaaacat tccagcgata atattgttcg
     4561 ggaaagtttc taattttaca ttgtagttgc tgacaacact gttatagagt tgacgagagt
     4621 aagaaatttt attttctgtg tttgtcaact cctcttgcaa tttaacaaag ttagcactag
     4681 ctttcaaatc tggatagctt tctgcaactg caaaaatacc tgaaacctga cgagtgaggg
     4741 catcactggc tttcatagct tctgctggtg aagtcgctgc cgccacttgg ttacgtagtt
     4801 ctgccacctt ttcaagggta gaaccttcat atttggcata accttttaca gtctcaatca
     4861 agtttggcaa gaggtcattt cgacgtttca actgaacatc aatctgactc caagcctcct
     4921 tggtttgcat acgattttta accaaaccgt tatagctaac aatcacaaaa ataacaataa
     4981 gagcgataac tccaagaata atccaagtca tgatataagt cctttctact tttagattag
     5041 taccagtata tcaaattttt aatgattgtg gtaaaataag atgatactaa agaaggaaat
     5101 aactatgaaa ccaaaaacat tttacaactt gcttgccgag cagaatcttc cactttcgga
     5161 ccagcaaaaa gaacaatttg aatgttattt tgagctcttg gtcgagtgga atgagaagat
     5221 taatttgacg gcgattacgg acaaggaaga agtttatctc aaacattttt acgattcgat
     5281 tgcacccatt cttcaaggtt tgattcccaa tgaaactatc aaacttcttg atatcggggc
     5341 tggggcagga tttcctagtc taccaatgaa aattctctat ccggagttag atgtgaccat
     5401 tattgattca ctcaataagc gcatcaactt cctacaactc ttggctcaag aactggattt
     5461 gaacggagtt catttctacc acggacgtgc cgaagatttt gcccaagaca agaacttccg
     5521 tgctcaatat gattttgtaa cagctcgtgc ggttgcccgt atgcaggtcc tatctgaatt
     5581 gactattccc taccttaagg ttggtggaaa actattggca ctcaaggcca gcaatgcgcc
     5641 tgaggagttg ttagaagcta agaatgccct caatcttctt tttagtaaag tcgaagacaa
     5701 tctcagctac gccctaccaa atagagatcc gcgttacatc acagtggtag aaaagaaaaa
     5761 agaaacacca aataaatatc cacgtaaggc tggtatgcca aataaacgcc cgctttaaat
     5821 ttttaagtaa aaaaatattt acaaaatcaa cctcgctctc ttatttttag gctcgggaaa
     5881 aaatgattta caaaatcagc ctcgctcttt tatttctagg ctcgggaaaa aatgatttac
     5941 aaaatcagcc tcgctctttt atttctaggc tcgggaaaaa atgatttaca aaatcatttt
     6001 tttctgctat actatcctaa gcaaaggttt ttaatgtcat cccgtgaggt gacgaagacg
     6061 cagaaatatt taaaactctt taaaatctaa attttaaaga agtcttactc tgagggccta
     6121 ttgctgtaaa ataatgggct cttttttgat gcccaaaagt gaggtttata tgaaacaaga
     6181 atcaactgtt gatttgttac tagacgttga ccaacgtcct tcggctggaa aaggaattct
     6241 ccttagtttc caacacgttt tcgccatgtt tggtgcgacc atcttggtac cattgatttt
     6301 gggaatgcct gtatctgttg ccctttttgc ttcaggtgtt ggaacactca tttacatgat
     6361 tgctactggt tttaaagttc cagtttatct aggttcttca ttcgccttta tcacagctat
     6421 gtcactggct atgaaagaaa tgggggggga tgtatctgct gctcaaacag gggttatctt
     6481 gactggtttg gtctatgtcc ttgttgctac cagcatccga tttgtaggaa caaaatggat
     6541 tgataaactc ttgccaccaa tcattatcgg tcctatgatc atcgttatcg gtcttggact
     6601 tgcaggttca gctgttacca atgcaggtct tgtagcagac ggaaattgga aaaatgctct
     6661 ggtagccgtt gttactttcc taattgctgc ctttatcaat acaaaaggaa aaggcttcct
     6721 acgaatcatt ccattcctct ttgccattat cggtggttac ctcttcgcac taactcttgg
     6781 tttggttgac tttacgcctg tcctagaagc taactggttt gaaattcctg gtttctactt
     6841 gccatttagc acaggtggtg cctttaaaga gtacaatctt tactttggtc cagaagccat
     6901 cgctatcttg ccaatcgcta tcgtaacaat ttctgaacat atcggagacc atactgtttt
     6961 gggtcaaatc tgtggccgtc aattcttaaa agaaccaggt cttcaccgta ctcttattgg
     7021 tgacggtatc gcaacttctg tttctgcctt ccttggtgga ccagccaata caacttacgg
     7081 agaaaataca ggggttatcg gtatgactcg tatcgcttct gtctcagtta tccgtaacgc
     7141 tgccttcatc gcgattgccc tcagcttcct tggtaaattc actgccttga tttcaactat
     7201 tccaaacgct gtacttggtg gtatgtcaat ccttctctat ggggttatcg ccagcaatgg
     7261 tttgaaagtc ttgattaaag aacgtgttga tttcgctcaa atgcgaaacc tcatcatcgc
     7321 aagtgctatg ttggttcttg gacttggagg agctatcctt aaacttggtc cagttacact
     7381 ttcaggtact gccctttcag ccatgacagg aatcatcttg aacttgatct tgccatacga
     7441 aaataaagac taagagtcta aatacaccta atccactcag ctgtctgagt ggatttttcg
     7501 tataccataa taaaagtgtc ttaacaaaat tattaaaatc aaaaaacgta taatatcaga
     7561 tattctaaaa ccttgatact gtacgtttta tcatagaaat ttttacttta ttttctcatc
     7621 aaatgagatt tgcatcaatc tcttgtctta cttgcgtttc ttcttcgctt tcttcatttt
     7681 gttagccata cgtttcatgg actgtttcat ggcaaattca ccaattttac ctttcaaacc
     7741 gccaccaaac atctggctca tatctggcat tcctgctcct ccgggagctg ataagtcagg
     7801 cataccgcct tgtcccatca ttccttcaag ggcagacata tccattcctc ccatatttgg
     7861 catattttta ggaaggttat ttggattaat ccccatttgc ttcatcattt tattcatatc
     7921 cccagacata acaccctgca tgagctgttt agcctggtta aagtccttga tgaatttatt
     7981 gacttcgacg aatgtatttc cagaaccagc agcaatacga cggcgacggc ttggatttaa
     8041 caaatctggg ttttcacgtt cttcaggtgt catcgaagac acaatggcac gtttacgagc
     8101 aatctggcgt tcatccacct tcatgttttg aagtgctgga ttattggcca tacctggaat
     8161 catcttgagc aagtcttcca ttggccccat gttttgtacc tgatccaact gatcaatgaa
     8221 atcattgaaa tcaaaggtat tttcgcgcat cttctcagcc atttcaaggg ctttttgttc
     8281 atcgtattcc tgagaagctt tctcaatcaa agtgagcata tcccccatgc caaggatacg
     8341 gctagacata cggtctgggt ggaaggtttc gatatctgta attttttcac ctgtaccagt
     8401 gaacttgatt ggttttccag tgatgtgacg aacagacaga gcagcaccac cacgagtatc
     8461 gccatcaatc ttggtaagga tgaccccagt cacttccaac tgagcattaa actcacgcgc
     8521 aacattggct gcttcctgac caatcatagc atcaacgaca agcaagattt catttggttg
     8581 agccaatgct ttcacatcac gaagctcatt catgaggagc tcatcaatct gcaaacgacc
     8641 cgcagtatca atcaagacat agtcgttatg attagtttgg gcttgctcca aaccttgacg
     8701 tacaatctca acagctggta cttctgttcc aagtgcaaag acaggcacat caatctgttg
     8761 tcccaaggtc ttaagctggt caatggcagc tggacgataa atatccgccg caatcatcaa
     8821 aggacgagca ttttcttctt tcttgagttt gttggccaat ttaccagcaa aggttgtttt
     8881 accagcccct tgtaaaccaa ccatcatgat gatgattgga atcttaggtg acttgataat
     8941 ttctgccgta tcagaaccta aaacggctgt cagttcctca tcaacgattt taataatctg
     9001 ttgcgcagga ttaagtgtat caatgacctg atgcccgact gcacgctcac gaactttctt
     9061 gataaagtcc tttacaacag gcaaggcaac gtcggcctcg agcaaggcca agcgaatttc
     9121 tttggttgcc tcttggacat cagattcaga gatttttcct tttttacgta gatttttaaa
     9181 gacgttctgc aaacgttctg ttaaactttc aaatgccatt tttcttcctc ttattctcta
     9241 ttatcaatgc ttgttaaaat ttctatctgc tcctgcagaa agttatcctt gggatagcgc
     9301 tccaaaatct gatcaaaaat ctgactgcgg acaatatagt ccgagtacat gtgcaatttc
     9361 atctcataat cttccagaat cttttctgtt cgcttgatat tgtcatagac agcctgacga
     9421 ctgacaccga actcctcggc aatttcagca aggctgtaat catcagcgta gtagagctcg
     9481 atataattca tttgcttatc tgtcaaaagc gccgcataaa attcaaagag cgcattcata
     9541 cgattggttt tttcgatttc cataactttt attataccaa aaattagcct aatctaccac
     9601 actaggaagc cgatccaaga agatagatag ctaaatttga aaaagacatg agcctagccc
     9661 caagtaattt ccaattgata gctggcaaag ggatgtccct cttgattttg tagttgataa
     9721 tctagttcaa tcttttgcct atcaacttga taatggctcg tttggatgat aaactcctgc
     9781 atgcccatag gtgtaggaat ataggctaaa ctatcgctat cctttagaaa gcgcataatg
     9841 gtcttgggat tagaaaatcg gctcatcaca agttcttgac catgaaattt aatcactact
     9901 ttttcctttt cctcattata aaagagtaaa tagctataat ttcccttttc atgcacttcc
     9961 acatcataaa gctggtcaat cacttccaac tgctcatcaa actgaatcgt atttcgcatc
    10021 cgaatcttca catcaagtcc tctttcttgt ctcttgtcct actattttac caaaaagagc
    10081 aggattttgc tataatggtc atatgaacga aaaagtattc cgtgacccag ttcacaacta
    10141 catccatgtc aataatcaaa tcatctatga cttgattaat acaaaagaat ttcagcgttt
    10201 gcgccggatc aaacaactgg gaacttccag ttataccttc cacggtggag aacacagtcg
    10261 cttctctcac tgtctaggag tctatgaaat tgcacgacgc atcacagaga ttttcgaaga
    10321 aaaatatcct gaggaatgga atcctgccga gtctctcttg accatgaccg ctgctctcct
    10381 acacgacctt gggcatggtg cctactccca tacttttgaa aatctctttg atacagacca
    10441 tgaagccatt actcaggaga ttattcaaaa tcctgagaca gagattcacc aagtcctgct
    10501 acaagtggca cctgatttcc cagaaaaggt ggccagtgtc attgaccata cctatcctaa
    10561 taagcaggtc gtgcagctca tttctagtca gattgacgca gatcgcatgg actatctctt
    10621 gcgcgactcc tattttacag gagcatccta tggggaattt gacctgactc gcatcctccg
    10681 agtcattcgt cctgtcgaaa atggtatcgc ctttcagcgc aatggcatgc acgccatcga
    10741 agactacgtc ctcagtcgct accagatgta catgcaggtt tatttccacc cagcaacacg
    10801 cgccatggaa gttctcctac agaatcttct caagcgcgcc aaggaactct accctgagga
    10861 caagaatttc tttgcacgaa cttccccaca tctcctgcct ttcttcgaaa aaaatgtgac
    10921 cttgactgac tatctggctc tggatgatgg cgtgatgaat acctacttcc agctttggat
    10981 gactagtcct gacaaaattc ttgcagattt atctcaacgc tttgtcaacc gcaaggtctt
    11041 taaatccatt accttttcac aagaggacca agatcaactt actagcatga gaaaattggt
    11101 tgaggacatc ggctttgatc ccgactacta tactgccatt cataagaact ttgacctccc
    11161 ttatgatatc tatcgtcccg aatctgaaaa cccacggaca cagattgaga ttttacaaaa
    11221 aaatggagaa ctggccgaac tctctagcct gtctcttatc gtccaatccc ttgctggcag
    11281 tcgccacgga gataatcgtt tctatttccc taaagaaatg ttagaccaaa acagcatctt
    11341 cgcaagcatt acccagcaat ttttacactt gattgagaac gatcatttta ccccaaataa
    11401 aaactagaag aggaaattta tgagtattaa actaattgcc gtcgatattg acggaaccct
    11461 agtcaacagc caaaaggaaa tcactcctga agtcttttct gccatccaag atgccaaaga
    11521 agctggtgtc aaagtcgtga ttgcaactgg ccgccccatc gcaggtgttg ccaaacttct
    11581 ggccgacttg cagttgagag accaaggtga ctatgtggtg accttcaatg gtgcccttgt
    11641 ccaagaaact gctactggcc atgagattat cagcgaatcc ttgacctatg aggattatct
    11701 ggatatggaa ttcctcagtc gcaagctcgg tgtccacatg catgccatta ccaaggacgg
    11761 tatctatact gcaaatcgca atatcggaaa atacactgta cacgaatcaa ccctcgtcag
    11821 catgcctatc ttctaccgta cccctgaaga aatggctggc aaagaaattg ttaaatgtat
    11881 gtttatcgat gaaccagaaa ttctcgatgc tgcgattgaa aaaattccag cagaatttta
    11941 cgagcgctac tccatcaaca aatctgctcc tttctacctc gaactcctta aaaagaatgt
    12001 agacaagggt tcagccatta ctcacttggc tgaaaaactc ggattgacca aagatgaaac
    12061 catggcaatc ggtgatgaag aaaatgaccg tgccatgctg gaagtcgttg gaaaccccgt
    12121 tgtcatggaa aatggaaatc cagaaatcaa aaaaatcgcc aaatacatca ccaaaacaaa
    12181 tgacgaatcc ggcgttgccc atgccatccg aacatgggta ctgtaaaagg aaagaataga
    12241 taaaaaccgc tcagctgagc ggtttttgta tgaatatatc acaatgagag taaattaata
    12301 aatttaattg cagttgtaca gttacttaaa tcttgagagt acaaaaaata ggcattgctt
    12361 tcttaatttg tggtactgaa ttgtaataaa tcactctcta tttctatatg ttatctcttt
    12421 ataatctctt ttaattttac gataatttca tatacaaagt ataaatagga aagtccttat
    12481 atctttcttt tgtctcatta tccagtttat tccaaaacaa atcagcttgt ggtttcgatt
    12541 ttaatagcac tgatgaaccg aaacaaagtt catagttatc attactattt actaaaatat
    12601 tagttagtgt ctctgtttct ttgctgttta atttacgaac tctagatttt atttgaaggt
    12661 catttattat agccatctca caattttttg agtattttaa gttccagtca gaaagacatt
    12721 gtgcccaatt aagcaataac tcacttctag aaacatcttc tgccttatca gcagccacaa
    12781 ctatttttat aatagtgtta ttagtacctt catatctcaa ttgattatca actaatcttt
    12841 ggtaagaggc aataaccgaa tcaaaatcac aattatctat ttttagccaa tagttaggtt
    12901 caaaaattga aatatctaaa ccaccttcat cttcacctct cctacaccaa ggagtttcag
    12961 taaagatatt aatcataaaa ccgttcttat ctattgcata atcatataag gtaataatat
    13021 ggatattagc aattcttaaa tgaagtaatt tggactcatt ataatctaag gcaaccttct
    13081 cctttagaac aagccctgaa tttaggatat ttagattttt ttgagattgt ttatcaaagc
    13141 agtttagatc tagatccttt tgtacaccta tattttttaa tatgttagaa atctgtttca
    13201 aatcctttat atcactatct aaattctgtg aagtgatatc cgatattgac tgcttatcta
    13261 gttctatttt atttccgttg agattgaaat atcctactct tcctagctct tggagcacct
    13321 ccgtacactc tatagctttt gatagcatat tggaccttgt atagttaaat ttaaatattt
    13381 ttttatttac atcaaaggac attttaaaac aatcaccaaa atggagttct acactcccat
    13441 caggaaaacg atgccttttt acatcttgaa aaatataatc accaacttta atgataagat
    13501 cagtctcttc gtacatttcg acaactttta tggtattttc aactggtact tcaacactag
    13561 taagaggatc tctgtaatat agaaaaagat catgcttttc ctgataacga aagatctctc
    13621 ctttcactgg accataaaag taaaacttta gatttttttc atcagtaatg tcctcaacgg
    13681 aaattccatc tgcatttatg aaactatact gcctctgact attgttaata aaatccacta
    13741 acattggata catttctttc tcatccaatt taaatatccg aacagaaagt ttcttactat
    13801 ttgtagtttt attatttaat ctactttttt tagcaatttt tttatagata aaggaggcaa
    13861 tgacttatag tatatttctc ttaaatcatt attttcactt agccagacaa cgaataaaac
    13921 cacaccacc
//
LOCUS       DAVFJR010000050        13790 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVFJR010000050 DAVFJR010000000
VERSION     DAVFJR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.051"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..977)
                     /locus_tag="VU722_001908"
     CDS             complement(<1..977)
                     /locus_tag="VU722_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HEU1772814.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVVSGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLPETQGDTVLTEVKPEVVAGNTNSLSTPTEGTEVSEET
                     SPSRLDTLFEKGEETQENPELTDVLKKAVDTADVDGTQASPEDIKKAVDEDVNDTIDV
                     PAAYLEQAKASGPFLAGVNKPLKYELFAGDGMLTRLLLKASDKAPWSDNGVAQNEKIP
                     PVKNLPDGKYYYQVSLNGNTEGKKDQDLLDTLRTNGTNTYEATLTVYEADGDKPDLTK
                     VVKTRNVNITLNGLVTKSDVKSAVENNVKDSIDVPAAYLEQAKGEGPFTA"
     gene            complement(1093..1503)
                     /locus_tag="VU722_001909"
     CDS             complement(1093..1503)
                     /locus_tag="VU722_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU1772815.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1570..2112)
                     /locus_tag="VU722_001910"
     CDS             complement(1570..2112)
                     /locus_tag="VU722_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1772816.1"
                     /translation="MRKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQ
                     TQEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLK
                     ILKTLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKG
                     QYIMMHSLIYRTDLLRASQF"
     gene            complement(2418..3083)
                     /locus_tag="VU722_001911"
     CDS             complement(2418..3083)
                     /locus_tag="VU722_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU1772817.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQNMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(3097..4476)
                     /locus_tag="VU722_001912"
     CDS             complement(3097..4476)
                     /locus_tag="VU722_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU1772818.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTYFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            4694..4981
                     /locus_tag="VU722_001913"
     CDS             4694..4981
                     /locus_tag="VU722_001913"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772819.1"
                     /translation="MKTKASIRELVTGCSKHCFEIVDRTDEVSSKHCFEIVDRTDEVS
                     SKHRFEVADRTDEVSSKHCFEVVDRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            complement(5221..5985)
                     /locus_tag="VU722_001914"
     CDS             complement(5221..5985)
                     /locus_tag="VU722_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU1772820.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(6202..6759)
                     /locus_tag="VU722_001915"
     CDS             complement(6202..6759)
                     /locus_tag="VU722_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEU1772821.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLYPLDPQERNSGIEYGKPITIGDNFWTGGGVIVFPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            complement(6865..7719)
                     /locus_tag="VU722_001916"
     CDS             complement(6865..7719)
                     /locus_tag="VU722_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1772822.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            complement(8075..12925)
                     /locus_tag="VU722_001917"
     CDS             complement(8075..12925)
                     /locus_tag="VU722_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1772823.1"
                     /translation="MSRKSIGEKRQSFSMRKLSVGLVSVTLASFFLMSQGIQSVSADN
                     MESPIHYKYMTEGELTDEEKSLLVEALLQLAEESDDTYYLGYIKTKKQDNAGISRTVD
                     GKYSARSDSQPDSTKISDVVHSADSEWSQGQGKVSLQGEASGDDGLSEYTDPVATKGT
                     QEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKIERQGQAGT
                     RTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLTKVENKKSI
                     TVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPYTVKTHLTY
                     NLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSEAPTDTAKY
                     FVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTFTVAKSKVE
                     QPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTGSLIGSDGT
                     KSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANINNVAVEGKI
                     SGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNSSRVNKVRV
                     DALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIVGSTWQNGR
                     VNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQIDAKVADYG
                     ITVTLDDTGQDLKRNLREVDYTRLNKAESERKVAYSNIEKLMPFYNKDLVVHYGNKVA
                     TTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVTFKENFINS
                     QVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGAANDAALDN
                     LYLDRKFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAFMLGLTYMN
                     RWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIIALGNSGLDNLRASNTVGLYANKL
                     ASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVREKQESPTAD
                     RKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERYRDSVDGVI
                     LSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGFNVKDETGR
                     TYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDAYGTSVYTH
                     EMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKAEKDDLNRL
                     HTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFRKIENYYVR
                     DTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKRNGYYTISM
                     FSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAFASGSKTFS
                     SWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITIQYELGNPN
                     STKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNAYLRTTDDF
                     RNSIYK"
     gene            complement(13041..13695)
                     /locus_tag="VU722_001918"
                     /pseudo
     CDS             complement(13041..13695)
                     /locus_tag="VU722_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         3947 a         3069 c         2381 g         4393 t
ORIGIN      
        1 gctgtgaatg gaccttcacc cttggcttgt tctaggtagg ctgctggaac atcaatactg
       61 tctttaacgt tgttctcaac tgcagatttg acatcgcttt ttgttacaag accgttcaaa
      121 gtaatattga cattacgtgt cttgacaacc ttagtcaaat caggtttatc tccgtctgct
      181 tcatagacag tcagggtagc ttcataggta tttgtaccat tcgtacgaag tgtatctaat
      241 agatcttgat ccttcttacc ttcagtgtta ccattcaaag atacttgata gtaatactta
      301 ccatcaggta aatttttcac tggtggaatt ttctcgtttt gagcgacacc gttatctgac
      361 catggtgcct tgtcagatgc cttgagcaag agacgagtca acataccatc gcctgcgaaa
      421 agttcgtatt taagcggttt atttacacca gccaagaacg gaccggaagc tttggcttgt
      481 tctaggtagg ctgctggaac atcgatagtg tcattaacat cctcatcgac agctttttta
      541 atatcttctg gacttgcttg tgtcccatcc acatcagccg tatctacagc tttttttaag
      601 acatctgtta gctctggatt ttcttgagtt tcttcacctt tttcaaaaag tgtatccaga
      661 cgggaagggc ttgtttcctc gctcacttca gttccttctg taggtgtaga aagtgagttc
      721 gtatttccag ccacgacctc aggtttcact tcagtcagaa cggtgtctcc ttgagtttct
      781 ggtaagtcac cctctttcgt tcccgatgtc tcttcaggta agacttgacc tggggtcgga
      841 ttgaccacat cggcacgtac agaacttggc tgaccaacta ggacaaagaa gccactaacc
      901 acaacaactg aggcaacacc gacactgaga cggcgaatag accaacgagt atatctttga
      961 tttggattga atttcatagg attctcctta gagtctttct ttatttgatg actctagtat
     1021 aatctcctga aattaaaaag gactaagaaa aagttaaaat ttttcttaaa tccctcttat
     1081 aaaacactta tattaattaa atccataaac agatttggtg atttgataga cgacattgga
     1141 cagtttgcga tctggcaaga cagaatgttt ggtcaaacgg ctcaacatgg tcttgcgaat
     1201 ggcctgaaag acttctggat tttcctgctg aatataggtc cacaattggc gcttttttgc
     1261 cagatgctcc gctgttccag atcggttgag cagggtactg gaaatcaccg tcgtgatttc
     1321 aatatgattc agcagatatt ctcgcatttt gggatgactc acttgggaca aatcaagctg
     1381 gtctaccaag agtcgattga ccttgagttg ctggtcaatg cacttaatca tcacttgctc
     1441 attgacagac tggtcctcac gcccaatcaa ataacgatag aaatcgacag gcagatagta
     1501 catggtcttg acctgctgaa ggggcgtaaa gacaaagaga ttatcgacat aaaaagcatg
     1561 ttcaggcaat tagaactggc tagcacgcaa caaatctgtc cgataaatca gcgagtgcat
     1621 catgatatac tggcctttag agaaatttcc gacctggtcc cagccaaaaa tctgccgaac
     1681 aggcaagact gaatcgtaac tcatactctt cttacgagac tgaccttcct tttcatagac
     1741 aaaattggtc acaaagacat ccacctcttg acccttgctc tcaagttcct gcaaggtttt
     1801 aagaattttc aagtaggcac gaggatccac ccagtcatca ctgtcaacta ctttaaaata
     1861 gcgcccagaa gcctctgcca agccacgatt gaccgcaccg ccatggcctt tattttcctg
     1921 atagatggct ctaacgatgt taggatactt gctagctaaa cactcagcga tttcctgagt
     1981 ctgatcctga gacccgtcat tgataatcaa aatctcaact tgctcaccac caatcactaa
     2041 cgactccaca cagtaatgaa gataggctgc tgcattatag ctagaaatgg cgatagacaa
     2101 taacttccta atctgctcct ttagggactg attttttctt atactcttcg aaaatctctt
     2161 caaaccgcgt caacgtcgcc ttgccgtata gatgttactg acttcgtcag ttctatctgc
     2221 aacctcaaaa cagtgttttg agcagcccgt agctagtttc ctagtttgat ctttgatttt
     2281 cattgagtat tactctctct tgtcacttct ttctatttta ccataaagtc cagcctttga
     2341 agaactttta ctagaagaca aggggcttct gtctctattt gccatcttgg gcatcaaaaa
     2401 agaggggtca tccctcttta cgaattcaat gctactaggg tatccaaata ctggttgttg
     2461 atgactgcca aaatataggt atctgctttc aagaggtcat ctggtccaaa ttcaacatcc
     2521 aatggggaat tttcctgctc tcggaaaccc aaaatattca gattgtattt gccacggagg
     2581 tctaatttac tcagactttg acctgcccaa gactgaggaa ttttcatctc cacgatagac
     2641 acatttttat ccaactgaaa gacatcaaca ctattatgga aaagaatggt ctgtgctaga
     2701 gactgcccca tttcatactc tggcgagata accgagtcag ctccaatctt ttctagcact
     2761 ttcttagcgg tctgactttt gaccttagca ataacagtcg gtacccccaa actcttacag
     2821 tgcataaccg caagcacact cgactccaga ttttcacctg tcgcgactac aacggtatcg
     2881 caggtatcaa tccctgctga tctcaataat tcttcatctg tgatgtcacc aatcactcca
     2941 cgcgccaaaa ctggctcaaa ctgattgatg cgctctgcgt ggtcatcaat agcgataata
     3001 ttcatattct gcttggctag ggcagctagg acactgctcc caaaaattcc caagcccaaa
     3061 attccaatcg tacgatctga catgctcttt cctttcttaa ccaatactaa tatctgcttt
     3121 catatagtga atcatatctt tcttttctgg atggtaatct gccaagctaa caaacaaggt
     3181 caagggacca attcgtccca taaacataag tggcatgata acactgagag ccaatttccc
     3241 aaggtcagga gtcagatttg ccgttacacc aactgtacta agagctgaaa tggtttcaaa
     3301 tatgaggtgg ataaagggag gattgccttt ggctgttatc cctagcagaa tcaatcctat
     3361 caagaagctc atcaaaaaga taataaagac actaaaggat ttttgaaccg ttcgcggcgc
     3421 aatcgttcgt ctcgcaacat tggcatgagg caagcctaga agctcacttc gtgcaaagac
     3481 caagaggaca aaatatgtcg taatcttgag tcccccagct gttcctccag gtgccccacc
     3541 tagaaacatc tgtaagatat aaatcaaaag agtcacagga tgagcctgag tataatctat
     3601 cgtagaaaag ccagctgttc gcatcgtcac tgtttgaaaa aagctaacta aaaccttatc
     3661 ggcaacaggg agattgccaa tcgttccagc attgttccac tcaagaaaga gagtagttgc
     3721 cgttccaaat aacaacaaac ctatagtcaa taatagtaca agcttcgtat gaaagtgcag
     3781 acgtcctttt ttctttcttc ctacatgacc agccaaatca aaccagacca taaaaccaag
     3841 gccgcctgta ataatcaagc ctgcaatcac cagattgacc agtaaatcgg tctgaaaagc
     3901 aaataaactg gtgctcccta aattatcaaa accggcatta cagaaggctg agatcgctag
     3961 aaaaatggaa ctaaaaagac cacgtcccca gccaagttga ggaataaggc gaaaactaag
     4021 caaaatagct cccaagctct caaccaaaaa ggtcgtgaga aaaatagaat agacaaactt
     4081 tctcaaagat cgagtttctc cataactaaa actatcctga atagttgcac ggctacgaag
     4141 actaagcttt tgcttgctct ggatatagaa aaccccaata aaggtcatga gccctagacc
     4201 accgatctga atcaagagca aacagattat ttggccccat atattatagg tgtgagctac
     4261 tggaagggtt gagagacctg tcacacagac tgcagagaca gcagtgaaaa gatgatcaaa
     4321 ataagtcgct cgtgagcttt caacttggac aaagggcaag ctcaaaagaa gagagcctag
     4381 taaaatgacc aaggcaaaac tcaaaaaaat acgacgggct ggcgataatc gagataagcc
     4441 tagctctatt ttttccttag ataatttgaa taacatgttt ccattgtacc ataaaaagct
     4501 cgaaatgact tagataggat aaggcaaaat ccactaacac caagcctaaa aaatgccacc
     4561 tttttattga tagcttaggc aagaacaata cttgatagat gtgactatag gtcaaaaaag
     4621 caagacagga gcttttaacg ccagctactc tatatgcttt tcaggagaaa atttctcttt
     4681 ttgattataa gcaatgaaaa ccaaggcatc gattagagag ctagtcacag gttgctcaaa
     4741 acactgtttt gagattgtgg atagaactga cgaagtcagc tcaaaacact gttttgagat
     4801 tgtggataga actgacgaag tcagctcaaa acaccgtttt gaggttgcag atagaactga
     4861 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagctcaaa
     4921 acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata cggcaaggtg
     4981 aagctgacct ggtttgaaaa gattttcgaa gagtatcatt tcatctcact ctaaatctta
     5041 ccaacataaa acgcatagta tcaaagtttt catcacctga tatgatacgt ttttctgatt
     5101 ttaaagattt ttcccaacct caacatgcct aggacaagag gaaggtgacc tcgtttaaac
     5161 atatttttga aaagtatgag ctagacattt tatgataaaa caaatccttt gccagtacaa
     5221 ctaaaggtgg tgaacacttg ctaaactcag ttctagcgcc ttattaaaag cttccgagcc
     5281 ccagtcacga ctgtcgtact ggtccaagtc cgctagagaa tctgctgtga acaacaattc
     5341 accccagaga accccacgca attgagctac tgccgcaaga gcagaacact ccatctccac
     5401 aacagcacag ccttcttcct tacgataagc caccttttca gccgtttctc ggtaaaaacc
     5461 gtctgtcgtc caggtcatga cttcttcata aggaatccct ctgtcttcca aaacttcctc
     5521 aatagcagca atagcctctg gctgcatttc catataacga gaaggtgcca catagtggta
     5581 actggctcct tcatctcgca gagcgcgaac agggactaga aaggcatttt cctctatatc
     5641 agctaggaca ccacaggtcc cagtagagat aatctgctcc acaccatagc caatcaacca
     5701 atccataaac tgggctgctg gagcggagcc aacaggagcc tgagccagac agacctcctc
     5761 acccttgtag ttgatgacat agactggata ggtcttggta gcagaaacga attcgccgac
     5821 acaatccgcc cctacttccc ttgcatagcg gtcaatctcc tcatctaaaa atgcataaac
     5881 acacttcttt ggcaactgca agtccagccc ctcgtgattg ggcatgataa ccgcctgagg
     5941 attgtcatca aactctaaaa taggaatcgc atgtttctga atcatagccc acctcctcta
     6001 attttgtact attgtatcaa aaactgacaa agtgtcaagg aggaagctga tgaactgagg
     6061 agaaaaacat cccacttacg agatgctttg aacttgctta atgaaacaga cttgctaaga
     6121 gatagagtag gtaaatgtga actgggtaaa aaatgatgaa acctacaaaa aagaaacaac
     6181 cccagctgtt cctttttact tctatttaac aggtatttcc ttaatcacgc gcgcaggatt
     6241 gccagctagg acaacgttgt cgccaaaaga tttggtaatt actgcccctg ctcctgcaac
     6301 gacattattt cccagtgtca ctccaggaaa gacaatgacg ccaccaccag tccagaaatt
     6361 atctccgatt gtgatgggct ttccgtactc gatacctgaa ttgcgttcct gtggatctag
     6421 tggatagagg ggtgtcaaaa actgacaatt aggaccaatc atagcattgt ccccgatacg
     6481 aatgggacag atatccagca tggtcaagtt ccaattagaa taaaaatttt cccctagatg
     6541 gatgttgaca ccgtagtcca ccatcaagcg agtgttgatg taaagatttt tcccggttga
     6601 ggcaaaccaa gtcttgatga tttcggctcc cttcaagggg ttctcttcct tgttaaaggc
     6661 ggcctgtttt tggcgagaag cctgagctaa ggctctcagt tctgggtctg atggacggta
     6721 aaactctcct gctatcattt tctggtattc gctagtcata ttattcttct ccttattccc
     6781 tactatcata tcaaattttc cacgtatctg actagaataa ggagcacttt ctacaattga
     6841 tgctctacct tcatcacata ccatctatct agctaaacga atacgggtca cgatgccatc
     6901 tgagtctgtg atttccaatt ggctcgatgt catccatttg attggtgcgt caacttcttg
     6961 tgctcgttgg gcaatcgtta acagttcttc tttatgtgcg acttcgatga catagtaggc
     7021 taaacctggt aggacttgtt tacgcggatc cagacctttt cctccccatt cgttgactgc
     7081 taaatgatga tggtagtccc cagctgcgat ccaactagca ctaggcacac tgaatttatc
     7141 ctcgagccct aacaccgttt gataaaactg tctggacttt cgactatcct tgacagaaag
     7201 atgaatatgc cccattctcg taccctctgc taggataaaa ggctctactc tttcccccaa
     7261 ctcatagata tcctgagccg caaggacttc agtcaccccg ataatacgtc catcttctcg
     7321 aatatcccat gtggaaactg gcttatctcg atagagttca atgccatttc cctccaagtc
     7381 ctctaagtaa agggcctcac tgtaaccgtg atctgcaccg ccaacaagag gaatctgtaa
     7441 atccgtcagg tgcttcaaga catccgccaa agcctttcgt gtcggcaaaa gaatagccag
     7501 atggtaaaga ccataatgtt cccttacttc tccaccctct tgtgcttgaa tcaagtgtac
     7561 caaggctttt cctccaagtc ccagaacgac ctctgtatcc gtttgagata ggatttctaa
     7621 accaataatc tgctgataaa aaactgtttg actgaccaaa tccttcacat ttaaaactgc
     7681 ctctgctaaa taaatgtggc tctggtattc atatgtcata aatatttcct cttttattgt
     7741 aactttaatc attacaacta ttatataact tccctcaaga aagtcaagcc agacaacttg
     7801 aagcatccca ctcagcaaaa aacaatccca gaaaaaatct tctaggattg ttttgtattt
     7861 attttactag actagcaaag ttatttctca aatcaacatt ttctgtggga ttgaaatcca
     7921 ccttgtcacc attggtcgtt gatgagttga agatgattcc tgcaatctgc attcaatcaa
     7981 atctctacat cgatccataa gaaaaaggag tcgatttgtc atctgactcc tcatccttac
     8041 aagaaacact actcaacaat gaaactctac aatcttattt atatatagaa tttctaaagt
     8101 catctgtagt gcgaagatat gcattataga ttttttgttt taataaatgc acccaacttg
     8161 ctggggtatg actcgttgca cgatctatat tagtaatatc tttcgcagcc gcttcattaa
     8221 ttaattgttg catttgtgca gccgttgtta tagttacttc ttttgtacta ttaggattac
     8281 ctaattcgta ttgaattgtt attggtttca gattatcttg tttatctata cgttgtttaa
     8341 acattgcttt tttgaaatca gcccatgatg agtactcacc attgaatact ttcttaaata
     8401 ctaaatcatc tgtcactaaa gcaacatctc ttccatgcca tgatgagaat gttttgcttc
     8461 cgctggcaaa tgcttctgct ccgtactgat tagaaacata aggtaggaat cctttgtgat
     8521 aacctttttc cgcaagtaat tcataagcta tttttctaaa cataatatct ccaggagcac
     8581 ctttcgaatt gcttagcgct gcgtatacag gagagaacat acttatagta tagtagccat
     8641 ttcgtttata ttctctatta tcatcatagc tacgtctatt tatgatgtcg ttgtcgatta
     8701 atgagtttaa cgatgttaag ttagctactt cttcatctgt taatggacgg actttatttc
     8761 ctgcatgtgt atctttatta tgtctagtat cacgaacgta ataattttct atttttctaa
     8821 accatttttt cttaacatca ttattttgag ctaatatcgc ttttgcttcc atcgcatcaa
     8881 gtgtatacat tacatcatat gatccatgca tataactttg aagcgcctca tccgaatcga
     8941 aacgttccac cggattatat gtatgcaatc tattcaaatc atctttttct gctttatata
     9001 acgtatttaa agctaaaata tgagaattta cactatctac agattgcagt aaaccaagtg
     9061 cgtataactc cgctcccaat ccttcacgtc taccatttcc ttcaaagtag attgcagaat
     9121 cagaattatg aaccatttca tgagtataaa ccgacgttcc ataagcatct aataatctat
     9181 ctaacacaaa gtgcgttaaa cttccattcg catacgctcc tgcactacta ttatactcat
     9241 accatttccc aacaggtccg aagaattctt taatagagcc gatgttttta tccgttaacc
     9301 ttgcccaata agttcttcct gtctcatctt ttacattgaa tccatcataa actatcacag
     9361 aacggaaaag tttttctttt gaagcactgt caagaagatt gtaccaaata tcataatggt
     9421 ctctatgcct tttcgctgct atatcaactc tatttcttac ataagttcgt aaagcatctc
     9481 ctgaaagaat aactccatcc acactatcac gatatctttc atacgaaccg aatgcaagtg
     9541 tagacatatt cgatgaaata tacacagatt cttcaggtaa agttagtagt ggtaataaca
     9601 tactcttatg cccccaactt ggtgctgata ttctatcgta aactcctaat gaatattttc
     9661 tatcggctgt tggtgattct tgtttttctc gtacttctgc aatatcagac ttcatttcga
     9721 ctatatatgc ctttgtattt tctttaaacc actcgttatt tgttttgttt ggtaagaaca
     9781 gttttctata cgcttctacg aagtcaaaga ctgaatcttc tccttttacc gatgcaagtt
     9841 tattcgcata taaacctaca gtatttgaag ctctcaggtt atctagtcca ctatttccta
     9901 atgcgataat agtatccaac gttgaagtct cattatttcc gttaaagtca aacttgtacg
     9961 tagataaatc ttttgtattc attttaccat aattaatatc gtaccaacgg ttcatataag
    10021 taagacctag cataaatgct tctttgttat ttttgatttt ctcacttacg tattcaacta
    10081 caccgtctcc tgtagtattg attgatttat ccatcgctaa tacttttctt aggtgttctg
    10141 ctatattagc tttaacttct tcaaattttc tatctaagta taggttatct aaggctgcat
    10201 cattcgctgc tcctagtact tttttagtag cttctgagtt aagtgttaca ttttgcaagt
    10261 cgcttagtac gttattcgtt atcgctgtat agtctgaaac aaatgcttct ggtgtgaata
    10321 tatattcttt tcctgtaaca ttgtattcga ttacttgact gtttatgaag ttttctttga
    10381 atgttacatc taggtattct actgtattat ctttgaaatg taacataact ttatttattg
    10441 aatttttctt attattaata tccgttacta cttcatcatc tttcatcggc acaacgtcta
    10501 acaattctgt agtgtaaagt ttatctgttg tcgctacttt gttaccatag tgaactacta
    10561 ggtctttatt gtagaatggc atcagttttt ctatgttgct ataagctact tttctttcag
    10621 attctgcttt atttagtctt gtataatcaa cttctcttag attacgtttt aaatcttgcc
    10681 cagtatcatc aagagttact gtgattccat aatcagcaac tttcgcgtct atttggtctt
    10741 ttgataattt tgtagcgaat ctgtctgctt ttctattatc aactgatgta cttgcatttt
    10801 tcacatctgc tgctgcgtat tgatcaccgg tgataacata accatctcca acatctacgt
    10861 tactcacaac attatttact cgaccgtttt gccacgtaga tcctactatt cctccgactc
    10921 tagaatatcc ttgaccattt cgtatttctc cagtagcaac cgaattagat atcaatgcac
    10981 cattttctaa tctacctact atccctccag ctgtttggtt attattgcgt gcattagtag
    11041 agattaaggc atctacccta actttattaa ctctcgaact atttcctgtt atattaccta
    11101 ctattcctcc agtatcattt ttattactgt cctggtgatt tgcgataagt ttccctgtaa
    11161 acgagctgtt ttctatcact gtatttgttg cgctcgctac taatcccgca acagatttcg
    11221 cacctgagat ttttccttct actgcaacat tattaatatt cgcgctattc gctgccttcg
    11281 ccagcgctgc gacattttct ttactatcag cagaaacagt tttaatatcc aaatctctaa
    11341 ctgtagcacc atttaatgta tcaaataatg gttttttcaa atcataaatg gcatacgatt
    11401 ttgttccatc agaaccgatc aagctccctg taaatgcacc tgtgagataa cttgtctgct
    11461 tatcgcctaa gctcacctca tctgcggtca tatctgaagc caatgtatag acaccagaca
    11521 gattgctttg catggctgtt accagctgtt taaaggatgt gtaaactcct ggttgctcta
    11581 ctttagattt agctacagta aatgtgtaat catctttgta accgtctgta ccttcttcga
    11641 caagttgatc aacggctacc gtcactttat acgttccatc cgtattttct gtaatagatt
    11701 ttacaggtag gtacatttct ttgaagcgat ctgatttcac ttttacaaag tatttagccg
    11761 tatcagtcgg cgcttcactt agacttaaat atctacgata acgatcattt tctttaccgt
    11821 ataattctac tgaatcaata tctttaatct ctattttctt atactctaat tggaaatctt
    11881 gagttgatgt ttcagtattt tcctcattat tttcacccaa attataagtt aggtgtgttt
    11941 taactgtata cggtgtgtag taatctaaac ctgatattac ttgctctttg gcaggatttt
    12001 ctatatccac ctctttaact agcttgtctc catggaaaac ttgcgttttt gcagaaacat
    12061 atgctgaggt agtgtctatt aagttataac ttacagttat agattttttg ttctcaactt
    12121 ttgttaagtt tgtaatttct actgtaggtt taactttcac aagtgttcct actttaacga
    12181 cttcgttgac cggagctact tcagttcgtg acacttcttt agtttctacg acattaccat
    12241 ttacgatgta gtcttcatat tgaattgtac gtgtccctgc ttgcccttgt cgttcaatct
    12301 tacgacgatt tttcagaagt gttggatcct gaatttcttc tgttgtataa ggaatattct
    12361 ggatttccgt tctatttcgt gtagtgacct ctaaagccgg aagttcttct tctactgccg
    12421 cttcgccctc atgttcgggt tcttgtgtgc cttttgtcgc tacaggatca gtgtactctg
    12481 aaagtccatc atcccctgat gcttcacctt gtaaactaac cttcccctgt ccttggctcc
    12541 attctgaatc agctgaatga actacatctg atatttttgt agagtctggt tgactatcac
    12601 ttcgagcaga gtatttccca tcgactgtcc ttgaaatccc tgcattatcc tgtttcttag
    12661 tcttgatata acccaagtaa taagtatcat ctgattcttc agccagttgt aaaagggcct
    12721 ctaccagcaa ggatttttcc tcgtctgtca attcaccctc ggtcatatac ttataatgaa
    12781 ttggactttc catattatcg gctgataccg attgaatccc ttgactcatc aaaaagaaac
    12841 tagctaaagt aactgatacc aatcccactg acaactttct catcgagaaa ctctggcgtt
    12901 tctcaccaat actttttcgg ctcatattaa cctcgctttt tctacattct ttataccaat
    12961 ctatattttg tagaataaaa gtataaacac aaaaaaatag tatagtatgg aattttctga
    13021 gtacttttca ataattatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta
    13081 acgatggact ttatcacctc cttctccagt ccttgtatga catcttggag ttgattcatg
    13141 acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac
    13201 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaaggtaaa gccaatatta
    13261 ctaggatgtt ctggatgtgg cgtaatattt cgccaaccat ggcgcttcaa cagttgatag
    13321 aaggcatcac gtgtgtagga acaacctaac tcctttttat aagcctgaaa taaggcatca
    13381 attgtaacaa attctcctgc ctctgcagcc ttcaaatggc gagcaagaaa aactttctct
    13441 tcctcaaccg tcatatatgc atggttacga ccaccacgag tttcttgaag gagagagtcg
    13501 agtccgaact cctcatattt ttttacattt cgccaaatcg ttgtttgatt acactctaaa
    13561 agctctataa tctctttata agatttaccc catcagacga aatagaacga tttgaaggcg
    13621 tttatgatat ttagctgtac tagagtcttt taaaagtgtt ttgatggctt ggatttcttc
    13681 tttagttgat ttcatattac tattatataa tgctttttga ttttagtcta gtattactta
    13741 tcattataca ataaatcgat agaaatttct attgaaatat acttaaaaat
//
LOCUS       DAVFJR010000051        13314 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVFJR010000051 DAVFJR010000000
VERSION     DAVFJR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.052"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            148..321
                     /locus_tag="VU722_001919"
     CDS             148..321
                     /locus_tag="VU722_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772824.1"
                     /translation="MQKKEQSSRQVVVGYLMDVMSVDIEEANHLVSGLEHEGLVCFES
                     NGDVTVLVLEGQS"
     gene            318..1145
                     /locus_tag="VU722_001920"
     CDS             318..1145
                     /locus_tag="VU722_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU1772825.1"
                     /translation="MKRITANHYQTSERYYKLPKLLFESERYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEEGAIYLVYSNSKLMALLGCSKSKLLTIKKTLREYGLIDEVQQSSS
                     EKGRLANKIYLGELEDDTSPVLKSDGGGVKKTRGQSQKQTGQVLNSAPSETEISETKK
                     NETERNESVIEDEEEKKEVTFGKKQEESLTRKVDHVTKYDVGYIWNLVYERLRQEGLS
                     RVTSEYAMVHFEDRYRYALEHMRFVNTAEAIAEYVFNGVLSEWSKQIRLNEAKKGGW"
     gene            1305..2663
                     /gene="dcm"
                     /locus_tag="VU722_001921"
     CDS             1305..2663
                     /gene="dcm"
                     /locus_tag="VU722_001921"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU1772826.1"
                     /translation="MKFLDLFAGIGGFRLGLTRQGHECIGFCEIDKFARKSYKVIYDT
                     EGEIEFHDIRQVTDQDFRQLRGQVDIICGGFPCQAFSLAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLSHDKGETFATILSTLDELGYDIEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYHPRFLFPLRGENSSAHLERLGNVNPSRKGMNGEVYLATGLSPTLTQN
                     KGEEAKIAIPVLTPDRLEKRQHGRRFKDNQDPMFTLTVQDRHGVVVAGTLPTSFVQTG
                     RVYDQSGLSPTLTTMQGGDKVPKIICREEAPHLKIKEATKLGYAKATVGDSVNLAYPE
                     STKRRGRVGKGISNTLTTSDNMGVVVAALEYRKDKWYEVTGIILDGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQAGNSVTVTVIEAIAREFRKIEEEEGHEII
                     TH"
     gene            2644..3072
                     /locus_tag="VU722_001922"
     CDS             2644..3072
                     /locus_tag="VU722_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772827.1"
                     /translation="MKLLHTKSIRDCTELEEVIHQAEVERIAETIASLPNYDCEIEVT
                     FEDDYHQEMNVPLAYESNLHRLFEFMETQDLKNGVDSYLAEENHLVFRAFGQHYMANG
                     KDDLLTTRITVKSFGEGRTPIDMSKVFTPLTQKLPKDLSV"
     gene            3082..3465
                     /locus_tag="VU722_001923"
     CDS             3082..3465
                     /locus_tag="VU722_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772828.1"
                     /translation="MLEIYLSRNTSRNQNLLSFYDTHGISYTPKEVNDLSREDLLSLF
                     TKSSDCFALLSPSLQRFKGHREMKLSELVTLVLRKPDQNLRLPLVICEDKVYPDMSLE
                     EARTFLPRTHKVVSFREHLFKQLTE"
     gene            3475..3708
                     /locus_tag="VU722_001924"
     CDS             3475..3708
                     /locus_tag="VU722_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1772829.1"
                     /translation="MNDRFWENLESIVIERGMSWADLARKMFKGQYVYPSEFKRLYQT
                     FRHYKSHHLMPQVKWVEKVVSVLEIDYEDLFRR"
     gene            3711..4292
                     /locus_tag="VU722_001925"
     CDS             3711..4292
                     /locus_tag="VU722_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1772830.1"
                     /translation="MRRILLAYGAIHVNVLLVSFFLVGVLNEVVLIALQVSFFALVLW
                     VWKCFKIPKRNLSLKERGLWLLVSLGVMVSTALIMSAIFSGYAVNQETLVTVQDQAPM
                     LPFILFLLNASVVEEVFYREVLWGVLSQPVVQFLLTSFLFTLAHHPSSLITWGLYGSL
                     GLVLGLVRLKADCFTSTLVHLSWNGIVFFLSLL"
     gene            4368..4856
                     /locus_tag="VU722_001926"
     CDS             4368..4856
                     /locus_tag="VU722_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772831.1"
                     /translation="MSSEQQERQALQYAERSTMFTVRVLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEWLNISKDILDKPIDVEKFKELMESENLPIAISWQGDYLYFY
                     AKDKSLLDKHLDKLLQKLVSNPEKLQGLTLDKTLDEEIAKAKEQIVMSEPSAVKAKEV
                     IL"
     gene            4856..6676
                     /locus_tag="VU722_001927"
     CDS             4856..6676
                     /locus_tag="VU722_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003086094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU1772832.1"
                     /translation="MASGKKAFIFGVLGLAFGYFCHRLVLLYDSLPNQPSIERFAYLL
                     GEGQNQVLNPLWKGNFTGRSVLGFCFGFVTMGLVYLYVSTGQRVYREGAEYGSARFGN
                     NRERKAFISKNPLNDTILSRNVRLTLLEKKAPQFDRNKNLVVIGGSGSGKTFRFVKPN
                     LIQLNCSNIVVDPKDHLAEKTGKLFLENGYQVKVLDLVNMTNSDGFNPFRYVETENDL
                     NRMLTVYFNNTKGNGSRSDPFWDEASMTLVRAISSYLVDFYNPPGSTKEEADSRRKRG
                     RYPAFSEIGKLIKLLSKGENQDKSVLEVMFESYAKTYGTENFTMRNWADFQNYKDKTL
                     DSVIAVTTAKFALFNIQSVIDLTKRDTLDLKTWGTQKTMVYLVIPDNDTTFRFLSALF
                     FSTVFSTLTRQADVDFRGQLPIHVRSYLDEFANCGEIPDFAEQTSTVRSRNMSLVPIL
                     QNIAQLQGLYKEKEAWKTILGNCDSLLYLGGNDEETFKFMSGLLGKQTIDVRSTSRSY
                     GQTGSGSTSHQKITRDLMTPDEVGNMKRDECLVRIAGVPVFKEKKYFPLKHKNWKYLA
                     DKETDERWWHYHIAPLKHEEESLDLSDHRVRDLSTETTLH"
     gene            6694..6936
                     /locus_tag="VU722_001928"
     CDS             6694..6936
                     /locus_tag="VU722_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772833.1"
                     /translation="MNQKLTGFVYGVDASSMFAQAMALLQKGMIATGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFITQITI"
     gene            6956..7807
                     /locus_tag="VU722_001929"
     CDS             6956..7807
                     /locus_tag="VU722_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HEU1772834.1"
                     /translation="MNTLPSAFVFLASEKISSDSLFEGFNVDLESTANLIKSLADYNP
                     TVWSYMSAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAIAPMMVSYIM
                     VAVVITNTTVIVEAILAAASHIIEGVAGVVSHGGATYETISGLKGSGIIGKLIVGFFA
                     ILIWLVRLVSVMVVNLLITIRFIQLYLMIPFAPLTIPTFLSDDWRSVGIGYLKNIMVY
                     ALQGVLIFLIISLVPLFESAGKLAVSNGAGVMETLATTFGGLVQAILLIIALVGSQRT
                     ARSILGM"
     gene            7997..8350
                     /locus_tag="VU722_001930"
     CDS             7997..8350
                     /locus_tag="VU722_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU1772835.1"
                     /translation="MNTRVFKDITKVQHRAWLGFTTRQVIFVLPAIALTILILGLNLF
                     YWQFGDWIVYGLIFTFTIPLMLFGVYRPNDLPFETYLNYRWHYEMTIPNRTLTGQKGI
                     RREKNKPLNETKDFF"
     gene            8328..10658
                     /locus_tag="VU722_001931"
     CDS             8328..10658
                     /locus_tag="VU722_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU1772836.1"
                     /translation="MKPKTSSKHKKTGKPKEKVLPTTANTLRYQGLFPNGLMQVTSDY
                     FSQSYLLGDVNYQTVGLEDKGAIMETYSDLINSLDDKTNFQLTIFNQRVNLDKFRKSV
                     LYPMHEDGYDTYREELNRIMENNLEAGENNFSAIKLISFGKSDQNPKLAYRSLSQIGE
                     YFKSGFSEIDANFTLLNGESRVNHLADMLRGENHLPFTYQDLVRSGQTTKHFIAPTSL
                     SFKHKNYIEIDDRLLQIVYVRDYGMELGDKFLRELMQSDLEVVISLHAKGSAKSEAMT
                     KLRTKKTLMESQKIGEQQKMARSGVYLEKVSQVLESNIDEADELIKTMTQTGDKLFDT
                     LFLIGVFADNADRLKHSLDIIKQVSGSNDLIIDNLSYMQEAAFNSLLPFGKNYLEGVS
                     RSLLTSNIAVNSPWTSVDLQDKGGKFYGINQISSNIITIDRGKLNTPSGLILGTSGAG
                     KGMATKHEIISTKLKEADTDTEIIIVDPENEYSIIGQSFGGESIDIAPDSTTFLNVLD
                     LSDDNMDEDPIKVKSEFLLSWIGKLLDRKMDGREKSLIDRVTRLTYKHFETPSLVEWV
                     FVLSKQPEQEAKDLALDMELYVEGSLDIFSHHTNIKTDSHFLIYNVKKLGDELKQIAL
                     MVIFDQIWNRVVKNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRVRKYGAIPTGI
                     TQNVETLLLDANGRRIIANSEFMILLKQAKNDREELVHLLGLSKELEKYLINPEKGAG
                     LIKAGSTVVPFRNKIPHQTKLFDIMSTDPEKMRTEA"
     gene            10655..>13314
                     /locus_tag="VU722_001932"
     CDS             10655..>13314
                     /locus_tag="VU722_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1772837.1"
                     /translation="MTSDKQNVKVARKTFQSSLKASRIHYRREKKGLKRSLPKRRFII
                     RRAEKAETREQRQTLKQTYQEETDLATDTFTKAISYVSPRWLKVKDIRKYRLPQARHR
                     LTVARKHLAENKMAEKEQAINPKFTYQKEPNQKTPSRFHFQKEKSLDRLQAEKKVNSA
                     KRDVKQLKRAHKAKKASTKFKRGLRYVASDSLDLVAQDDDLEGIRTVKDMSIKGRRYG
                     RFIYQSGKLLVTSGQTGMRFTKTKIAHGKERYQNFKKGKGFTRQKPLKHKRRYHTFLK
                     QARKHSVSGIKGVIQAIKGSLTFFSTIVLNPMTWVVSGLLFFLLLMMSFVVGISGTSL
                     IQQDEGELTKAYTHMTWEDAENTRTNDTGITYYTKIDDVMGFMNLKYQDYALEEVMEN
                     GDKTYQVYLSQLWHDLNGGDSLKAMLELTKEPAYKLSDDDREELKELSKEGTYLALQE
                     LDNPFQGQTEDDTLTMTVRYGYEMIEDKPTLHHHIILEAKENQVIVAPMDGKVSLDGE
                     NLIITSGKGLNKSQLTLFNVHTGRVTDGQKVQAGEMIGQTKDGSGLKVTYQKVDNDSE
                     KLVYVNPAFYFPKVIQLQTTILPTIGQFGGDEFARAKVIYEYLKSQGATNQAIAAILG
                     NWSVESSINPKRAEGDYLSPPVGATDSSWDDEGWLSLNGPAIYNGRYPNILRRGLGLG
                     QWTDTADGSRRHTLLLKYAKRQNQKWYDLDLQLDFMLHGDNPYYTNWLKDFFKNSGSP
                     ASLAQLFLIYWEGNSGDKLLERQTRAAEWYYQIEKGFSQPNGGTAQSDPKALEAVRED
                     LYDNSIPGGGDGMGYAYGQCTWGVAARINQLGLKLKGRTGEKISIINTMGNGQDWVGT
                     AARLGGETGKLPKAGAIISFAGGQYGHVGFV"
BASE COUNT         3998 a         2576 c         3069 g         3671 t
ORIGIN      
        1 ataggtgctt aaaacgctga taaatcaagg atttgagcgt tctacaatct gtcattaagg
       61 aggaaatttt tgttttaata agagaatatc gctatagcga gaacatttta ataggtgttc
      121 tcgctttttt attttcagga ggaaaatatg caaaagaaag aacagtcatc acgtcaagtt
      181 gtggtgggtt atctcatgga tgtcatgagt gttgatattg aggaggccaa tcacttggtc
      241 tcaggcttgg aacatgaagg cttggtttgc tttgaatcaa atggagatgt cacagtatta
      301 gtattggagg gacaatcatg aaacgcatta ccgcaaatca ctatcaaacg tcagagcgtt
      361 actataagct cccaaaactc ttgtttgaga gtgagcgtta taaggatatg aaactagaag
      421 tcaaggtagc ctatgctgtt ttaaaagatc gtttggaatt atctttgagt aaaggctgga
      481 ttgatgaaga gggggctatt tatttggttt attccaactc aaaactgatg gctctccttg
      541 ggtgttccaa gtcaaagttg ctgacgatta agaaaacgtt aagagagtat ggcttgattg
      601 atgaagtcca acagtcttct agtgaaaaag ggcgcttggc caataagatt tatttagggg
      661 agttggaaga tgacactagc cccgtcttaa aatcagacgg gggtggtgtt aaaaaaacac
      721 gggggcagtc tcaaaaacaa acggggcagg tcttaaattc agcccctagt gagactgaaa
      781 taagtgagac taagaaaaat gagactgaaa gaaatgagtc agtcattgag gacgaggagg
      841 agaaaaaaga agtcactttt ggaaaaaaac aagaagaatc tctcactcgt aaagttgatc
      901 atgtgacaaa atacgacgta ggctatattt ggaatttggt ctatgaacgc ttgcgacaag
      961 aaggcttgtc tcgagttacg agtgaatatg cgatggttca ttttgaggat cgttatcggt
     1021 atgctttaga gcacatgcgt tttgtaaata ccgctgaagc gattgctgaa tatgtcttta
     1081 atggggttct atccgaatgg agtaagcaga tacgactaaa tgaagcgaag aaaggtggtt
     1141 ggtgaacaga tgttttggtg gatcgtatta ggaatctgga gactagggtt gatttggcta
     1201 attgttgcaa tcatcacggc accagacatg gacgattata attgaggtag gacgttacgt
     1261 aaaatgtaag gtccttttag ttttgtcaga aaggaaggag agacatgaag tttttagatt
     1321 tatttgctgg aattggaggc tttcgactgg ggttaactcg tcaaggccat gaatgtattg
     1381 gtttttgtga gattgacaag tttgcgagga aatcttacaa agtcatctat gatacggaag
     1441 gagaaataga atttcatgac attagacaag tcacagacca agactttaga caactcagag
     1501 ggcaggtgga catcatctgt gggggattcc cttgtcaagc attttcactc gcaggcagac
     1561 gattgggatt tgaggacact aggggtactc tgttctttga gattgctcga gcggccaaac
     1621 agatccaacc acgtttttta ttcctcgaaa atgtcaaggg tttactcagt cacgacaagg
     1681 gagagacgtt tgccacaatc ctctctacat tggatgagct ggggtatgat atcgaatggc
     1741 aggtgcttaa cagtaaagat ttccaagtcc cacaaaaccg agaaagggtc tttattatcg
     1801 gacattctag aagataccat cccagattct tatttcctct cagaggagaa aatagctcag
     1861 ctcatcttga aagattagga aatgtcaatc cgtccagaaa aggcatgaac ggtgaggtct
     1921 acctagcaac aggtctctcg cctactttga cgcaaaataa aggagaagaa gcaaagattg
     1981 ccattccagt cttaacccct gatagactgg agaaacgcca acatggcaga cgttttaagg
     2041 acaatcaaga ccccatgttt accctaacgg ttcaagatag acacggtgtt gttgtcgcag
     2101 gaacccttcc gacctctttt gtgcaaactg ggcgagtcta tgaccagtct ggcctatccc
     2161 ctacccttac caccatgcaa ggaggggata aagtgcctaa gattatctgc cgtgaagaag
     2221 ctccgcattt gaaaatcaag gaagcgacca aattaggcta tgctaaggca acagtgggag
     2281 attctgtcaa ccttgcttat ccagagtcaa ccaaacgcag aggacgagta ggaaagggaa
     2341 tctcaaatac cttaaccact tctgacaata tgggagtggt ggtagctgct cttgaatacc
     2401 gtaaggacaa gtggtatgaa gtgacaggaa taatcctaga tggaaaactt tatcgtttga
     2461 gaatcagacg attgacccct agagagtgtt ttagacttca ggggtttcct gactgggctt
     2521 atgaaagagc agaaagcgta tcaagtaaaa gtcagttgta caaacaagca ggcaatagtg
     2581 tgactgtcac cgtcattgaa gctattgcta gagaatttag aaagattgaa gaggaagaag
     2641 gacatgaaat tattacacac taaaagtatt agggactgta cagagctgga agaagttatt
     2701 catcaagcag aggtagaaag gattgctgag acgattgctt ctttacccaa ctatgattgt
     2761 gagattgagg tcacttttga agatgattac catcaggaga tgaatgttcc attggcttac
     2821 gagtccaact tacatcgact ctttgagttt atggaaacgc aagaccttaa aaatggcgtt
     2881 gacagttatc tagcagaaga gaaccatctc gtttttagag cttttggtca acactatatg
     2941 gcaaatggaa aagacgattt attgaccaca cggattacag taaaaagttt cggtgaaggc
     3001 aggacaccca ttgatatgag taaggtgttt actcctctta ctcaaaaatt accaaaggat
     3061 ttatcggtgt aggaggaaga aatgctagaa atctatttaa gtcgaaatac cagtcgaaat
     3121 caaaatctcc tttcttttta tgacacgcat ggtatttctt acactcctaa agaagtgaat
     3181 gacttgtcac gtgaggactt actgagcttg tttaccaaaa gcagtgattg ttttgccctc
     3241 ttatcccctt ctctacaacg gtttaaaggt catagagaga tgaaattaag tgaattagtc
     3301 acgttggttc tcaggaaacc tgatcagaat ttgcgattac ctctggtgat ttgtgaggat
     3361 aaagtgtatc ccgatatgag tttagaagaa gcgagaacct ttctaccaag aactcataag
     3421 gtggtgtctt ttcgtgagca cctctttaag caactaacag aataaggagg agctatgaac
     3481 gaccgctttt gggaaaattt ggaaagtatc gttattgaaa gaggcatgtc atgggctgat
     3541 ctcgctcgaa agatgtttaa gggtcaatac gtttatccta gtgagtttaa acgtctctac
     3601 caaacctttc gtcactacaa atctcatcac ctcatgccac aagtcaaatg ggtggagaaa
     3661 gtggtgagcg tcttagagat tgactatgaa gacttgttta ggaggtagac atgagaagga
     3721 tattgctggc gtacggagcc attcatgtta atgttctttt ggttagtttc tttttggtag
     3781 gagtgctaaa tgaggtagtg ctaatagcct tacaagtttc tttttttgct cttgtactgt
     3841 gggtctggaa atgttttaag atacctaaaa gaaatttatc cttaaaagag agagggcttt
     3901 ggttgcttgt cagtcttggt gtcatggtga gtacggctct tatcatgagt gccatctttt
     3961 caggatatgc ggtgaaccaa gaaacgttag tgacggttca agatcaagca ccaatgttgc
     4021 cttttatcct ctttctcctc aatgccagtg tggtggaaga agtattttac agagaagtgc
     4081 tgtggggagt cttgtctcaa cctgtggttc agtttctgtt aacgagtttc ctctttactt
     4141 tagcccatca cccatctagt ctcatcactt gggggcttta tggtagttta ggactggtgc
     4201 taggactagt tcgcttaaag gctgattgtt tcacctcaac cctcgttcat ttgtcttgga
     4261 atggaattgt ctttttcctg tctttgttgt gataccaaaa tcaagggtac tttcgtatca
     4321 tgaaagcacc ctagtgttta taagggaatc atgccaagga gggaatgatg tcatccgaac
     4381 aacaggaacg ccaagcgtta cagtacgcag agagaagcac tatgtttacc gttagggttc
     4441 tcctcaagct cttagagtgg tccgctagac aagctttggc acaagactcg gcctataaga
     4501 ttggggttca aaagttagaa gaactccttc aaagccctta tgccattgag tggcttaata
     4561 tctcaaaaga catcttggat aaacccattg atgtcgagaa attcaaggaa ctgatggaat
     4621 cggagaatct gcctattgcc attagttggc agggagacta cctttatttc tatgctaagg
     4681 ataaatcttt gttagataag cacttggata agttgcttca gaagttggtt tccaatcccg
     4741 aaaaactgca aggcttaact ctggataaaa ccttagatga ggaaatcgct aaagccaagg
     4801 aacagattgt gatgtcagaa ccttctgctg tgaaggccaa ggaggtaatt ctctaatggc
     4861 ctcagggaaa aaagctttta tctttggtgt tttaggactt gcctttggct atttttgcca
     4921 tcgcctagtc ttgctttacg atagtctccc aaatcaacca tcgattgaaa ggtttgccta
     4981 tctcttagga gaaggtcaga atcaggtttt aaatcccttg tggaagggca actttactgg
     5041 tagatcggtt ttagggtttt gttttggatt tgtgacgatg ggactagtct atctttacgt
     5101 ctcaactggt cagagagtct accgagaagg ggctgagtat ggctctgctc gttttggaaa
     5161 caatcgggag cgtaaagcct ttatcagtaa gaaccccttg aacgatacta tcttatctcg
     5221 aaacgttagg ctaactctct tagaaaagaa agccccacaa tttgaccgaa acaagaactt
     5281 agtggtcatt ggtggatcag gatcagggaa aacctttcgc tttgtcaaac ccaatctgat
     5341 tcagcttaac tgttccaata ttgtcgttga tcctaaggac cacttagctg aaaagacagg
     5401 gaagctcttt ttagaaaacg gctatcaggt caaggtctta gacctcgtaa acatgaccaa
     5461 ctcagatggc tttaatccct ttcgttatgt ggaaacggag aatgatttga accgtatgct
     5521 tacggtctat ttcaataata ccaaaggcaa tggcagtcgc agtgatccct tttgggatga
     5581 agcttccatg accttagtga gagccatttc ctcttactta gtggattttt acaatcctcc
     5641 tggtagtacc aaggaagaag cagacagtcg ccgtaagcgt gggcgttacc cagccttttc
     5701 agaaattgga aaactcatca agctcttatc caaaggggaa aatcaagata agagtgtctt
     5761 agaagtcatg tttgagagct atgccaagac ctatggaacg gagaacttta ccatgcgtaa
     5821 ctgggcagac ttccaaaact acaaggataa gaccctggat tcggtgattg ctgtaacaac
     5881 tgctaagttt gccctcttta atatccaatc cgtcattgac ttaaccaagc gtgatacctt
     5941 ggacttaaag acatggggga cgcagaaaac tatggtctat ctcgttattc cagataatga
     6001 caccaccttt cggtttctct cagcactttt tttctccacc gtcttttcaa ccttaaccag
     6061 acaagctgac gtggacttta ggggacaact gcctatccac gttagaagtt acttggatga
     6121 gtttgcgaat tgtggtgaaa tcccagactt tgcggaacaa acctcaacgg ttcgctccag
     6181 aaacatgagt ctcgttccta tccttcaaaa cattgcccaa cttcaaggac tttataagga
     6241 gaaggaggct tggaaaacga ttctagggaa ctgtgatagt ttgctttatc ttggtggcaa
     6301 tgatgaagag accttcaagt tcatgagtgg tctcttaggc aaacaaacca ttgatgtaag
     6361 aagtaccagt cggtcgtatg ggcaaacagg gtctggttct acctcccatc aaaaaattac
     6421 gagggatctc atgacccctg atgaagtcgg aaacatgaaa cgagatgagt gcttggtgag
     6481 aattgcaggg gttcctgttt ttaaggagaa gaaatatttc cctttgaaac acaagaactg
     6541 gaaatatctc gcagataagg agacagatga gcgttggtgg cattaccaca ttgccccctt
     6601 gaaacatgag gaggaaagtt tggacttatc agaccacagg gttagggatt taagcacaga
     6661 aaccacacta cactaataga aatgaggaat cgtatgaacc aaaaattaac aggctttgtt
     6721 tatggcgtgg atgcaagttc catgtttgcc caagccatgg cacttttaca aaagggaatg
     6781 attgcgacag gagcctttct tgtcgtgatg ggcattatta acctttcaac caatatcaaa
     6841 gatggtggac ctggtgttcg caatgccatc ttagaaattg tgggtggtgt catggtgggt
     6901 gccgctggtg cctttatcac tcaaattacc atttaggagg gctaggtatg acaagatgaa
     6961 tacattacct tcagcttttg tctttctagc ctcagagaaa atttcaagtg atagcctctt
     7021 tgaaggcttt aacgtagact tggaatcgac cgctaacttg atcaaatccc ttgcggatta
     7081 taacccaacc gtatggtctt atatgtcggc catcacaaag ggaatcatgc agcccttggg
     7141 agtggctatt ttagctgttg ttctagtcct tgagttttct aaaatggcta agaaaatcgc
     7201 caactcaggt ggagccatga ccttcgaagc cattgcccca atgatggtct cttatatcat
     7261 ggtggctgtg gtcattacaa atactactgt gattgttgaa gccatcttag ccgctgcttc
     7321 tcacatcatt gaaggagtgg ctggcgtcgt ttctcatggg ggagcgactt atgagaccat
     7381 ttcagggtta aaagggtcag gaattattgg aaaattgatt gtcggcttct ttgccatttt
     7441 gatatggctg gttcggttgg ttagtgtcat ggtagtgaat cttctcatta ccattcgctt
     7501 tatccaactt tatctcatga ttccttttgc gcctctaacc attccaacct tccttagtga
     7561 tgactggcga agtgttggga ttggctacct gaaaaacatc atggtctatg ccctccaagg
     7621 agtcttaatt ttcttaatca tctcccttgt gcccctcttt gaatctgctg ggaaattagc
     7681 tgtttcaaat ggagcaggag taatggagac gttagcgact acctttggtg gcttagtcca
     7741 ggctatttta ttaatcattg ccttggtggg cagtcaacgg actgcaagaa gcatcctagg
     7801 catgtgagag taggacagga atcggtactg ctttgcagtc gaaggcgtcg tcttacctcc
     7861 gcaaggacga ctagaactgt catagctagg aactagcgta gagagttcag acgtctactg
     7921 cgtcaaagac atgaaaccgt tcaaactgga ctgagatttc catcttagtc ctttttcaaa
     7981 gaaggagcta ctatttatga atacacgtgt ttttaaggac atcacgaaag tccaacatag
     8041 ggcttggttg ggctttacca cacgacaagt catctttgtc ttgccagcta ttgccctcac
     8101 aatccttatc ttaggactga acctttttta ttggcaattt ggggattgga ttgtctatgg
     8161 acttattttt acttttacca ttcctctcat gttatttggg gtctatcgtc ctaatgactt
     8221 gccctttgaa acttatctta attatcgatg gcattacgaa atgactatac caaaccgcac
     8281 actaactgga cagaaaggaa tacgccgtga gaaaaacaaa ccactcaatg aaaccaaaga
     8341 cttcttctaa gcataagaag acaggtaaac caaaagaaaa ggtcttgcca acaactgcca
     8401 atacccttcg ttaccaagga ctttttccta atggtctcat gcaagtcaca tctgattatt
     8461 tttcccagtc ctatctttta ggagatgtta attaccagac ggtaggactt gaagataagg
     8521 gagcgattat ggaaacttat tcggacttga ttaacagttt ggatgacaag accaatttcc
     8581 aattaaccat ttttaaccaa agagttaact tggacaagtt tagaaagagt gtcttgtatc
     8641 ccatgcatga ggatggctac gatacttacc gtgaagaact caatcgtatc atggagaata
     8701 acctagaagc tggtgaaaat aacttttcag ctattaagct tatttcgttt gggaagtcag
     8761 accaaaatcc gaaactggct tatcgctctc tttctcaaat tggggaatac ttcaagagtg
     8821 gtttttcaga aatagatgcg aactttactc tcctcaatgg agaaagccgt gtgaatcact
     8881 tggctgatat gttgcgaggg gaaaatcatc tgccctttac ctatcaagac ctggtgcgtt
     8941 cgggacaaac gaccaagcat tttattgccc caaccagtct atcctttaaa cataagaatt
     9001 atatagagat tgacgataga ctccttcaga ttgtttacgt tcgtgattat gggatggaat
     9061 tgggggacaa gttcctacgt gaactcatgc agtctgattt ggaagtggtc attagtttac
     9121 atgccaaagg ctcagccaag tcagaagcta tgaccaagct ccgcaccaag aagaccttga
     9181 tggaatcaca aaaaattggg gaacaacaaa agatggcacg atcaggtgtc tatcttgaaa
     9241 aggttagtca ggtcctagaa agcaatatcg atgaagctga tgagctgatt aaaaccatga
     9301 cgcaaacagg agacaagctc tttgacaccc tctttttgat tggggtcttt gcggataacg
     9361 cagatcggtt gaagcactca cttgacatta tcaagcaagt gtcaggttct aatgatctca
     9421 ttattgataa tctttcctac atgcaagaag ctgcctttaa tagcttgtta ccttttggaa
     9481 agaactatct tgaaggtgtg tctcggtcac tcttgacttc aaacattgcc gtcaattccc
     9541 catggacttc cgttgattta caagataagg gtgggaaatt ctatgggata aatcagattt
     9601 caagtaatat tatcaccatt gaccgtggga aactcaatac cccatcaggt cttattttag
     9661 gaacatcagg tgctggtaag ggaatggcaa ccaagcatga aatcatctca accaagttaa
     9721 aagaagcaga tactgatacc gaaatcatca ttgtcgaccc tgaaaatgag tatagtatta
     9781 tcggccaatc ctttggtggg gaaagcattg acatcgcgcc tgactctact acctttttaa
     9841 acgtcttaga cctatctgat gataacatgg atgaagaccc tatcaaggtc aagtcggaat
     9901 ttcttctctc ttggattgga aaactcttag accggaaaat ggatggtcgc gagaagtcac
     9961 tgattgatcg tgtgacacgg ctcacctata agcattttga gacaccgtcc ttagtagaat
    10021 gggtctttgt cctctccaaa caacctgaac aagaagccaa ggatttggct cttgatatgg
    10081 aactctatgt ggaaggctca cttgacattt tctcacacca caccaacatc aaaaccgata
    10141 gtcattttct catttacaat gttaaaaagt taggggatga attgaagcag attgccctca
    10201 tggtcatctt tgaccagatt tggaatcgtg tggttaaaaa tcaaaaacta gggaagaaga
    10261 cttggattta ctttgatgaa atgcagcttc tgttgctgga taagtacgct tctgatttct
    10321 tcttcaagct ctggagccgt gtccgtaagt atggggcaat tccaacaggg attacgcaga
    10381 acgtggaaac tcttttgtta gatgccaatg gcagacgcat tatcgctaat agcgaattca
    10441 tgattctctt aaaacaagct aagaatgacc gagaagagtt ggttcatctt ttgggcttat
    10501 ccaaagagtt ggagaaatat ttgatcaatc ctgaaaaggg agctggattg attaaggcag
    10561 ggtcaacggt tgttcctttt agaaataaaa tcccacatca aaccaaactc tttgacatca
    10621 tgagcaccga tccagaaaag atgaggactg aagcatgaca tcggacaaac agaacgttaa
    10681 ggtagcccgt aaaacctttc agagtagttt aaaggctagc cgtattcatt accgtaggga
    10741 gaagaagggg ctgaaacgct cacttcctaa acgacggttt atcatcagac gggcagaaaa
    10801 agctgaaacg agagaacaaa ggcaaacctt gaaacagacc taccaagagg agacagacct
    10861 agcgacagat acctttacaa aagctatctc ctatgtgtca cccagatggc taaaggtcaa
    10921 ggacatcaga aagtatcgcc ttcctcaagc cagacatcgc ttaacagtag cgagaaaaca
    10981 cttggcagag aacaagatgg cagaaaaaga gcaggctatc aatcctaagt tcacttatca
    11041 gaaagagcca aaccaaaaga ctccttcacg atttcacttc cagaaagaga aaagtcttga
    11101 ccgccttcag gcggaaaaaa aggtaaactc agcgaagcgt gacgtgaagc aactgaaaag
    11161 agcccataag gctaagaaag cctctacgaa attcaaacga gggttacgct atgtcgcttc
    11221 agactcactt gatttagttg ctcaagatga tgacctagaa ggaattcgaa ccgtaaagga
    11281 tatgagtatc aaaggcagac gctatgggag gttcatctat cagtcaggaa aattgcttgt
    11341 gacaagtgga cagactggta tgcgttttac caagactaaa atcgcccatg gcaaggaacg
    11401 gtatcagaat ttcaaaaagg ggaaaggctt cacccgtcag aaacccttaa aacacaaaag
    11461 acgataccac acttttctca aacaagctag gaaacacagt gtgtcaggaa taaaaggggt
    11521 tattcaagcc atcaagggaa gtctaacctt cttttcaaca attgtcctca atcccatgac
    11581 ttgggtcgtg tcaggtctct tatttttctt gcttttgatg atgagttttg tcgttggaat
    11641 ttcaggcacc agccttatcc aacaagatga gggtgagctg acaaaagcct atacgcacat
    11701 gacgtgggaa gatgcggaaa acaccagaac caacgatact ggcattacct actacacgaa
    11761 aattgatgac gtcatgggct ttatgaacct caagtatcaa gattatgctt tagaagaagt
    11821 tatggaaaat ggggataaga cctatcaagt ttatttgagt cagctttggc atgacttaaa
    11881 cggtggggat tctttaaaag ctatgcttga gctaaccaag gagcctgcct acaaactctc
    11941 ggatgacgat agggaagaat tgaaggaact aagtaaggaa ggtacctacc ttgccctaca
    12001 agaattggac aatccttttc aaggacaaac tgaagatgat acgctaacta tgacggttcg
    12061 ctatggctat gagatgattg aggacaagcc aacgcttcat caccatatca ttttagaagc
    12121 caaagagaac caagtgattg tggcacccat ggatggcaag gtatcgcttg atggagagaa
    12181 ccttattatc acgtcaggta agggtctcaa taagtctcaa ctgaccttgt ttaatgtcca
    12241 tacaggtcga gtgaccgatg gccaaaaggt tcaagcagga gagatgattg gtcaaaccaa
    12301 agatggttct ggtctcaaag taacctatca aaaggttgac aatgattcag agaaactggt
    12361 ttatgtcaat ccagcctttt attttccaaa ggtgattcaa ctccaaacga ccattctacc
    12421 gactattggt caatttgggg gcgatgagtt tgcgagagct aaggtcatct atgagtattt
    12481 gaaaagccaa ggtgcgacca atcaagcgat tgcggctatt ttagggaact ggtcagtaga
    12541 atcctctatc aatcctaaac gagcagaagg tgactactta tcgcctcctg tgggggcaac
    12601 ggatagctct tgggacgatg agggatggtt gtcccttaat ggtccagcta tctataatgg
    12661 caggtaccca aatatcctaa gacgtggctt aggattaggt cagtggacag atacggcaga
    12721 tgggtcacgc agacatacgc tcttattaaa atatgccaaa cgacaaaatc agaaatggta
    12781 tgacttagac ttacaactgg atttcatgtt gcacggagat aatccttatt acaccaactg
    12841 gttaaaagac ttcttcaaaa attcaggaag tccagctagt cttgcccaac tctttctcat
    12901 ttattgggag ggaaatagtg gcgataagct cctagaacgt caaacaagag ccgccgagtg
    12961 gtattaccaa attgagaaag gctttagcca acctaatggt ggaaccgccc aaagtgatcc
    13021 aaaagcactt gaagctgttc gagaagacct ttatgataat tctatcccag gtggtggtga
    13081 tggcatgggc tatgcctatg gtcaatgtac ttggggagtg gcagctcgga tcaaccaact
    13141 aggcttgaaa ctcaaaggca gaactggtga gaaaatctca atcatcaata ccatgggaaa
    13201 tggtcaagat tgggtaggca ctgcggcacg tcttggtgga gagacaggaa agttacctaa
    13261 agcaggagcg attatctctt ttgcgggtgg tcagtacggg catgttgggt ttgt
//
LOCUS       DAVFJR010000052        12428 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVFJR010000052 DAVFJR010000000
VERSION     DAVFJR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.053"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            186..3287
                     /locus_tag="VU722_001933"
     CDS             186..3287
                     /locus_tag="VU722_001933"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU1772838.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRVAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKECQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRATGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3370..4377
                     /gene="pfkA"
                     /locus_tag="VU722_001934"
     CDS             3370..4377
                     /gene="pfkA"
                     /locus_tag="VU722_001934"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU1772839.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4436..5941
                     /gene="pyk"
                     /locus_tag="VU722_001935"
     CDS             4436..5941
                     /gene="pyk"
                     /locus_tag="VU722_001935"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU1772840.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6626..6851)
                     /locus_tag="VU722_001936"
                     /pseudo
     CDS             complement(6626..6851)
                     /locus_tag="VU722_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7699..8571
                     /locus_tag="VU722_001937"
     CDS             7699..8571
                     /locus_tag="VU722_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU1772841.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQYATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8717..9061)
                     /locus_tag="VU722_001938"
                     /pseudo
     CDS             complement(8717..9061)
                     /locus_tag="VU722_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9204..9515
                     /locus_tag="VU722_001939"
     CDS             9204..9515
                     /locus_tag="VU722_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772842.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKYSI
                     K"
     gene            9519..10235
                     /locus_tag="VU722_001940"
     CDS             9519..10235
                     /locus_tag="VU722_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1772843.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQVPKEIASLMNEWLAYFL"
     gene            complement(10364..11179)
                     /locus_tag="VU722_001941"
     CDS             complement(10364..11179)
                     /locus_tag="VU722_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU1772844.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKRVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHDNSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11176..12081)
                     /locus_tag="VU722_001942"
     CDS             complement(11176..12081)
                     /locus_tag="VU722_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU1772845.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PEKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         3892 a         2166 c         2631 g         3739 t
ORIGIN      
        1 gttctaggag atttatatta tatgctttct gtttttatat acaatatagt ataaatataa
       61 aaacgatgac aaaaatacaa atgaatagaa aataaattag taagctgatg aaatttttct
      121 caagagaagc catttatagg tgaaaatggt ataatatagt gagaaggata gaggagaagt
      181 gtaaattgat cgcacaacta gatacaaaaa cagtctatag ttttatggaa agcgtcattt
      241 cgatcgaaaa gtatgtgaga gtagctaaag aatacggcta cactcatttg gctatgatgg
      301 atattgacaa tctttatggc gctttcgact ttctagagat tacaaaaaaa tacggcattc
      361 atcctttgct agggcttgaa atgacagtgt ttgtagatga tcaggaagtg aatttgcgct
      421 ttttagctct atctagtgtg ggctatcagc agttgatgaa gctttcgaca gccaagatgc
      481 agggggagaa aacttggtca gtcctgtccc agtacctgga agatatcgcg gtcattgtgc
      541 cttattttga tagagttgag tcgttagaac taggctgtga ttactatata ggggtttatc
      601 cagaaacact agcaagcgaa tttcatcatc ctatcttacc tctttatcgg gtcaacgctt
      661 ttgaaagcag ggatagagaa gttcttcaag ttttaacagc gattaaagaa aatctaccgc
      721 tcagagaagt tcccttgcgt tcgagacaag atgtctttat atcagcaagt tctttagaga
      781 aactattcca agagcgtttt ccgcaagctt tggacaattt agaaaagctt atttcaggca
      841 tttcttacga cttggatact agtctgaaac tgcctcgttt taatccagct agaccagcag
      901 tagaggagtt gagagagcgt gctgaactgg ggcttgttca gaaggggttg actagtaaag
      961 aatgtcaaga tagactagac caagaattgt ctgttattca tgatatgggc tttgatgatt
     1021 atttcttggt tgtttgggat ttgttgcgtt ttggacgatc gaatggctat tatatgggaa
     1081 tgggaagggg ttctgcagta ggcagtttgg tttcttatgc cttagacatc acggggattg
     1141 acccagtaga gaaaaatctg atttttgaac gctttcttaa tcgtgaacgc tataccatgc
     1201 ctgatattga tattgatatc ccagatattt atcgtccaga ttttatcaga tatgttggta
     1261 ataaatatgg tagtaaacat gcggcacaaa tcgttacttt ttcaaccttt ggagccaagc
     1321 aagctcttcg agatgtcttg aaacgctttg gtgtgccaga gtatgaatta tctgcaatta
     1381 ctaagaaaat cagttttcgt gacaatctta agtcagccta tgagggcaat ctccagtttc
     1441 gtcagcaaat caatagtaag ttagaatacc aaaaagcttt tgagattgct tgcaagatag
     1501 agggctatcc aaggcaaacc tctgtccatg cggctggtgt tgtaattagt gaccaagatt
     1561 taaccaacta cattcctcta aagtatggtg atgaaattcc actgactcag tatgatgctc
     1621 atggagttga ggctagcgga cttttgaaga tggactttct gggactacga aatttgacct
     1681 ttgtccagaa gatgcaagag ttgcttgctg aaacagaagg tattcatctg aaaattgaag
     1741 aaatcgattt agaagacaaa gaaacgttag ctttatttgc ctctggtaat acaaaaggta
     1801 tctttcaatt tgagcaacca ggtgccattc gtctgcttaa gcgtgtgcaa ccagtctgtt
     1861 ttgaagatgt cgtcgcgact acttctctaa atcgaccggg tgctagtgac tatatcaata
     1921 attttgtggc aagaaagcat gggcaggaag aagtgactgt tctggatcca gtactggagg
     1981 atattttggc tccaacctac ggcatcatgc tctatcagga gcaggttatg caggttgccc
     2041 agcgacttgc cggatttagt cttgggaaag ccgatatttt gcgtcgggcg acggggaaaa
     2101 aggatgcctc tgccatgcat gagatgaggg cttcctttat tcaaggttca ttagaagctg
     2161 gtcatactgt ggaaaaagca gagcaggtct ttgatgttat ggagaagttt gcaggttatg
     2221 gttttaacag gtcacacgcc tatgcctact cagccttggc cttccagttg gcttatttca
     2281 aaacgcatta tccagccatt ttttatcagg tcatgttaaa ttcttccaac agtgattact
     2341 taatagatgc acttgaagca ggttttgaag tagcctctct atccatcaac accattccct
     2401 atcacgataa aattgccaac aaggccatct atctaggttt gaaatccatt aaaggagtca
     2461 gtaatgattt agctctctgg attattgaaa atagacctta ttctaacatt gaagatttta
     2521 tagctaaatt acctgagaat tatctgaaac ttcctctgct agaacctttg gtaaaagttg
     2581 gtcttttcga ttcatttgaa aaaaatcgtc aaaaagtatt taataactta gctaatctat
     2641 ttgaatttgt gaaagagttg ggaagtttgt ttggagatgc tatttatagt tggcaggaat
     2701 cggaagattg gacggaacaa gaaaaatttt atatggaaca agagctttta gggataggtg
     2761 tcagcaaaca tccactacaa gctattgcaa gtaaggctat ttacccgatt accccaatcg
     2821 gaaatttgtc agaaaatagc tatgctatta tcttggttga agttcagaaa ataaaagtga
     2881 ttcgtaccaa aaagggtgaa aatatggcct tcttacaggc agatgatagt aagaaaaaat
     2941 tggatgtcac tctcttttca gacttatatc gtcaggttgg acaggaaata aaagagggag
     3001 ccttctacta tgtaaaagga aaaatacaat cacgtgatgg ccgtctgcaa atgattgcac
     3061 aagaaataag agaagcagtt gctgaacgct tttggataca ggtgaaaaat catgaatcgg
     3121 atcaagaaat ttcacgcatt ttagaacaat ttaaaggccc aatcccagtc atcatccggt
     3181 atgaagagga acagaaaacc atcgtttctc cccatcattt tgtagctaaa tccaatgaat
     3241 tagaggagaa attgaatgaa atcgttatga aaacgattta tcgctaaaaa tacggaaaat
     3301 agaagaattt taaaatcaaa tgtgatataa tcaagaagaa tgttaaaaga aaaaggagca
     3361 taaaccaata tgaaacgtat tgctgttttg actagtggcg gagacgcacc tggtatgaac
     3421 gctgccatcc gtgcagttgt tcgtcaagca atttcagaag gaatggaagt gtttggtatc
     3481 tatgacggat atgctggtat ggttgccggt gaaattcatc ccctagatgc agcttcagta
     3541 ggagacatca tttctcgtgg tggtactttt cttcactcag ctcgttatcc agagtttgct
     3601 caacttgaag ggcaacttaa agggattgag caattgaaaa aacacggaat tgaaggtgta
     3661 gttgttatcg gtggtgacgg atcttaccac ggcgctatgc gtttgactga acatggcttc
     3721 ccagctattg gtcttccagg tacaatcgat aacgatatcg ttggtactga ctttacaatc
     3781 ggttttgaca cagcggttac tactgccatg gacgctatcg ataagattcg tgatacatca
     3841 tcaagtcacc gtcgtacttt tgtaatcgaa gttatgggac gtaacgctgg tgatatcgct
     3901 ctttgggctg gtattgcaac tggtgctgat gaaatcatca tccctgaagc aggcttcaag
     3961 atggaagata tcgtagcaag catcaaagct ggttatgaat gtggtaaaaa acacaatatc
     4021 atcgtcttag ctgaaggtgt gatgtcagcg gctgaatttg gtcaaaaact taaagaagct
     4081 ggagatacaa gcgaccttcg tgtaacagaa cttggacata ttcaacgtgg tggttctcca
     4141 actgcgcgtg accgtgtttt ggcgtcacgt atgggtgcac atgctgttaa acttcttaaa
     4201 gaaggtatcg gtggtgttgc ggttggtatt cgtaacgaaa aaatggttga aaatccaatt
     4261 cttggtactg cagaagaagg ggcattgttt agccttactg cagaaggtaa gattgtggtt
     4321 aacaacccac acaaagccga tattgagcta tctagcttga ataagagctt gtcataattt
     4381 acaatttagt taataagacc aaaaaggtca tatatataaa ggagtcacaa aaatcatgaa
     4441 caaacgtgta aaaatcgttg caactttggg tcctgcggta gaaatccgtg gtggtaaaaa
     4501 attcggtgag gacggatact ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat
     4561 tgctaaattg attgaagctg gtgctaacac attccgattc aacttctcac acggcgacca
     4621 ccaagaacaa ggtgagcgta tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa
     4681 agttggtttc cttcttgata caaaaggacc tgaaatccgt acagaattgt tcgaaggtga
     4741 agctaaagaa tattcataca aaactggtga aaaaattcgt gttgcaacta aacaaggaat
     4801 caaatcaact cgtgaagtga ttgcgttgaa cgttgctggt gctcttgata tctatgatga
     4861 tgttgaagtt ggtcgtcaag ttttggttga cgatggtaaa cttggtcttc gtgtggttgc
     4921 taaagatgat gcaactcgtg aatttgaagt tgaagttgaa aacgatggta tcatcgctaa
     4981 acaaaaaggt gtgaacatcc ctaacactaa aattcctttc ccagctcttg ctgaacgcga
     5041 taacgacgat atccgtttcg gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt
     5101 acgtactgca aaagatgtga acgaagttcg tgcaatctgt gaagaaactg gaaacggaca
     5161 tgttcaattg ttcgctaaaa tcgaaaacca acaaggtatc gataacttag acgaaatcat
     5221 cgaagcagct gatggtatta tgattgctcg tggtgatatg ggtatcgaag taccgttcga
     5281 aatggttcca gtttatcaaa aaatgattat caagaaagtc aatgctgcag gtaaagttgt
     5341 tatcactgca acaaacatgc ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga
     5401 agtatcagac gtattcaacg ctgttatcga cggaactgac gctacaatgc tgtcaggcga
     5461 gtctgcaaac ggtaaatacc cactcgagtc agtaactaca atggctacaa tcgacaagaa
     5521 cgctcaagct cttcttaatg aatacggacg tcttgattca gattcatttg agcgtaactc
     5581 taagacagaa gtaatggctt ctgctgttaa agatgctact aactcaatgg atatcaaatt
     5641 ggttgtaact cttactaaga caggtcatac tgcacgtttg atttctaaat accgtccaaa
     5701 tgctgacatc ttagcattga catttgacga attgacagaa cgtggcttga tgttgaactg
     5761 gggtgttatc ccaatgttga cagatgctcc atcttcaact gacgatatgt tcgaaatcgc
     5821 tgaacgtaaa gcggtagaag caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc
     5881 tggtgtgcca gtaggagaag ctgttcgcac aaacacaatg cgtatccgca cagtacgtta
     5941 agaaaaatat aaaaacctat catatccagc tttagagctt gtgtgatagg ctttttgtat
     6001 agagggtaag aaagaggcaa aactttcata atggattgat actcttcgaa aatcaaattc
     6061 aaaccacgtc agcgtcgcct taccttactc aagtacagct tgcggctagc ttcctagttt
     6121 gctctttgat tttcattgag tatgaaataa gatatgcaca aattgattag aaagtcaaat
     6181 gaatttctac aaatgtttta gcaatcgtaa tgtacttgtc tagattcgat ctgatatatt
     6241 ttcgatttaa tgatatggta tttaaaacct ccaaagtagc ttgctccatt cttttactta
     6301 cgtgagtgta gatgttattt actgttttag cgtttttgtg ttccactcta accattatag
     6361 cattcttctc agctagtgta ctaaggagtg tgtgcctgaa aatatgggaa ctaaggggct
     6421 ggtttatcgg tttctctagt ttagtatttg ccttttgcaa agtgatctta aatgcctttc
     6481 tctaaattta catatcacta ttgtttaaca aaatctaatc tactttaggt cacttattct
     6541 ttttttgaaa tgtagaatga actttttcaa agtttttcga atcttttaaa atctgtttgt
     6601 tttatatcgc cattctcccc cttttttaat tctccctata tagcctgaca actttcccga
     6661 tggtacgaat atggttgctt tcgtctaggt ggatgtcggg gtatttggga ttgagttttt
     6721 ttaaggtagc cttggcggag tttcttgaca tagttagcgc cgtctacttg gaagatgccg
     6781 atggtattat agtcaatctg tggggtattc ttgataaata ggtagtcgct gtttcttatc
     6841 tttggctcca tggacttgct gacgacataa gcgattgggt cgtagtcgtc tgggataatg
     6901 gaaactccat atctaaatcg ttgtcctgca tcgagcggct acctgcagag ataaactacc
     6961 taacacgaga gtaagtagtc tgtctgtagt cgtccagtct gatgattttt acgatacttc
     7021 gtttttctgc tcatacagtt gcctctaggc ataggttagg actttacctt gtctgggtgg
     7081 tgcccgttgg tcgtagatag attggatatc gctaggagaa tccttttgaa ctggaggaaa
     7141 gagggcatcg atcaagctac tgaatacttt aactaagtca aatatagtat ttttcttagt
     7201 agacctaacc cttttttcat aatttctaat ggtgttttta cttataccta tcttagtacc
     7261 caattcttat tgagtccaac cattactagt ctatattgtt ttatagttga ttgagtttgg
     7321 aatagtacgc tgtagctgct aaaacatttc taggaattaa tttgcctttc ctaatagagt
     7381 tgttcatatc ttatttcaat ctactatatt tttcacctct aacaattgca atctcttctt
     7441 tatccatgaa tgaaatcgct ttctgttttt gtaagtaaag cataacacga aatccacgaa
     7501 aatgaaaacc tttgttgtgt tttcgtaaaa aatttgttga cagagcacga aacgcctact
     7561 ataattaaat caagcttaag gaaataacaa aaaaacaaat cggagggaaa gacgatgaac
     7621 acattaaatg agaaagtaat caatatctgt aaagcagtag ttaaagaaac tttaatccaa
     7681 gacatttagg agaaagaaat gaagaaatca agaaaattag ccacattagg aatctgttca
     7741 gctttgtttt taggcttggc tgcttgtcaa caacaatatg ctacttctga ggggacgaat
     7801 caaaggcaaa gcagttcagc gaaagttcca tggaaagctt catacaccaa cctaaacaac
     7861 caggtaagta cagaagaggt caaatctctc ttatcagctc acttggatcc aaatagtgtt
     7921 gatgcatttt ttaatctcgt taatgactat aataccattg tcggctcaac tggcttatca
     7981 ggagatttca cttcctttac tcacaccgaa tacgatgttg agaaaatcag tcatctctgg
     8041 aatcaaaaga agggcgattt cgttgggacc aactgccgta tcaatagtta ttgtcttttg
     8101 aaaaattcag tcaccattcc aaagcttgaa aagaatgacc agttgctttt cctagataat
     8161 gatgcaattg ataaaggaaa ggtctttgat tcacaagata aggaagagtt tgatattcta
     8221 ttttcgagag ttccaactga ggcaactaca gatgtcaagg ttcacgctga aaagatggaa
     8281 acattcttct cacaatttca attcaatgaa aaagctcgaa tgctgtctgt agtcttgcac
     8341 gacaatctgg atggcgagta tctgtttgta ggccacgttg gggtcttagt acctgctgat
     8401 gacggtttct tatttgtaga gaaattgact ttcgaagagc cctaccaagc gattaaattt
     8461 gctagtaagg aagattgcta caagtatttg ggcaccaagt atgcggatta tacaggcgag
     8521 ggactggcta agccttttat catggataat gataagtggg ttaaacttta atagtgttat
     8581 gatatgacag taatcttagg atttttattt ctatttttga tgagttggtg ggttatttca
     8641 atcgttaata gccagaaacc acgcaaaaat gaaacattta ttggctatat ccaaagatac
     8701 gatattgatg ggaatggcta tcaatcatta ccgtgtcctc agaactgaga ggagttcttg
     8761 aaaccgtaaa accgctttga acaagagtta cttcaaccca ttggctccga cggagtaagt
     8821 tgctttcgtg aataccaaaa tcagccgcaa tttcttcata agttcgatat tctcgcacat
     8881 attgaagagt ggccataaga aggtcttcta ggcttaattt aggttttcgt cccccttttg
     8941 cgtgtttaag ttgataagct gtttttaata cagctaagat ctcttcaaaa gtggtacgct
     9001 gaacaccaac aagacattta aatcgtgcat cagttagttg tttacttgct tcataattca
     9061 tagaactact ataccatatt ttgtttcgca ggaagtctaa tgctaaaatc ttatcagtga
     9121 gaagatttct taaagtttat tctttgtagt ttcatctgta ttagtacata atttaaccta
     9181 gagaaaatag gaggactaat cgaatggaat taaaagattt tacagaaaaa gaacaggaaa
     9241 tgattaagaa aaggcttaca atgtctaata ttagtgacaa agaaactgct gagaagattc
     9301 tggcgctagt accacaagac ttgattaagc gaatcccgtt ttttgtcaga aaacatgcta
     9361 caacacgtac gattaaacgc atttcaattg aacaccctga actctacgct gtagctcaaa
     9421 caagtggtga gattccagaa aaagaacgcg aagaattgcg tcagattatc acaactatct
     9481 ttgaacaaaa gatgaataag tatagtatta agtagagaat gaaaaaatat tttattggcg
     9541 gtttgggaag caatgcctat catagcaagg attttcttca agaactagat tcgcaggtct
     9601 attttctaaa tccatatgaa aagcatcttc gagatgaaac agaattgaaa tcatggttta
     9661 aaaatgagat tgtagaggag gaatctatct gtctgatagg tcattctctt ggaggagatt
     9721 tagctcgtta tttcgcatcg gaatttgaag aagtaaagaa actgattctt ttggatggtg
     9781 gctatctaga tttagataag attttacctt tggatacaga gttagaggaa actaaaaatt
     9841 atatcaaatc tcaaattatt tcggacttag ctcttcttat ttctaaagaa aaatctgaag
     9901 caaagcattg gtcagaaaat atggagaaag ccgtaagaca atcctatcac tggaatgttg
     9961 agtataatag atatgagttg gctataaatt atgaaaatat agaagcgata ctccgcctac
    10021 ggagaaaaat acaagctttt aagagagaag tgggagatac cttgtttatt agtcctcgct
    10081 atcctaatga agctacatgg agagaggaag ccctaaaaga attgccagac tattttgata
    10141 ctattttttt agaaaacttt ggccatgagc tttatactca agtgcctaaa gaaatcgcta
    10201 gtctaatgaa tgagtggctc gcttattttc tatgagctac ttgtattgct ggaaatggta
    10261 taagatgaaa atctacaagt cactaatttt catataacaa aaaacgaaca ggctcttttt
    10321 ctgttattca gaagagaact tgttcgtttt tatcttgatt ttcttaaaaa gctctatata
    10381 catagggatt ttctggttta tcgactttgg taaagctgtc gatttccaag gttggaaggt
    10441 tttgtttgag ttctttatgg tagtgattga ccagttttcc tttggctgaa atccaagtgt
    10501 tgttttcata ctgccgggta ttgcccttgg tcagcaatcc atagacacca gaatctgcga
    10561 tacagtggat aatgccgaag cggaacagaa attggctatt gtcatgactg gggtcgttat
    10621 agacaaagcc tgtaaactgg attgtcttgc cctcaaactc atctggatag tcgtagatag
    10681 cctccatgac ttccatatag ttttcattag tgatctgaat actatcttgg gataagtatt
    10741 tatccgccgc cgttcgcatt tccttttcat aggctgattt tgaaaaataa gaactggtat
    10801 ctggtttcaa atattggctt gtcgtccctt cgcttgtctg aatggctaga tccgttcctt
    10861 ctgatagggg gaaatgataa cctttagcag aaacggtctg agaatccaag ctaacagttg
    10921 ggaaagttaa gccgatgaca agtggaatag ccagaagaga aatactcgtc atcttggcca
    10981 atcggctgtt cagatgactg tgggttttga ctcgcttcat ccagatatac aattgaacga
    11041 tagccaagat aaaagaaagt accatggaaa tataggctag ataggaatag tgcatgttga
    11101 tgtactggtt tagtttgccc gacagatgga ggtaaatagt cagttcaaaa tagccagcta
    11161 aaactaaaaa tcgaatcata ggatgactcc aatcaagaga gaatagacta agacgacaag
    11221 agttacaatc gttatgaagt gactgataaa tcgtgctttc aagtaatttt tcatcatgag
    11281 aatatttttg atatccagca ttggaccaat gacgagaaag gccagaactg gtgccaaacc
    11341 gaaactcgag agaagagaag cacctataaa ggcatccgcc tcactacaga gcgaaagaag
    11401 aaaggccaaa atcatcaaga gcaggatggc aaaaagaggg gttgcactga tagaggtcag
    11461 aatccgagtc ggaacgtaga cctgtattat agaagcaaag aggcaaccaa ataccaaata
    11521 acgccccgta tcaaaaaatt catcaatggc ctgcacaaag acttgaaaaa ctttttttgc
    11581 agaactcaag taagaaaaat catgctcatg acaagccaga cgattttctt tctgaatcgg
    11641 ttcttgccag aaaaatccta gaaaaattcc tagtattaca gccacaagaa tggaacccag
    11701 agctcgtaat agggcgacat ggaaggagtt gccaaaggca gaataggtcg caaaaagaac
    11761 aatgggattg ataacaggtg ctgtcacaag aaaaggaacg gccgtgtaac ttggaacctt
    11821 tttttccaga aaacgattga taatggggac gattccacat tcacaagaag ggaaaagcat
    11881 accgacgaag gtcccaaaaa agattcttcc ccaacgattt cgagggagaa aatgataaac
    11941 cttttcaggt gtgatataaa cctcaatcag ccctgagaca atgcttccta tcagaacgaa
    12001 gggaagggct tcaatgataa tggagagaaa aatggctcca gtttgaagta cactagatgg
    12061 gagttgttga aaagcagtca tctagttttt cttttctgct ttggcttttt tctctttgtc
    12121 atcagggaaa gtaacttgtt tcaaatcagg gagtttagca aactcttcaa acatcttgtc
    12181 caagtcgtct cgttttgtaa attttacagc cataggtgta cctcgattct aaatcctacc
    12241 tctattatac tattattttg cggaaaagga agttttttaa tttgttttcg atagttgata
    12301 ctcttcgaaa atctcttcaa accacgtcag cttcgccttt ccgtagtacg gttactgact
    12361 tcgtcagttc tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agtcttatct
    12421 acaacctc
//
LOCUS       DAVFJR010000053        11984 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVFJR010000053 DAVFJR010000000
VERSION     DAVFJR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.054"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..11019
                     /locus_tag="VU722_001943"
     CDS             <1..11019
                     /locus_tag="VU722_001943"
                     /inference="COORDINATES: protein motif:HMM:NF020018.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU1772846.1"
                     /translation="GAVAASETITPTTASDVVKAGSDGNADGNPASSDEGDSKQALTD
                     KPAELKAADELKTQEAPAEGANQTSSTGILQPRTLKNNQSDYDPIPIEDDEDDVRDGL
                     FSSENPVTTIQPRSSHSVTGRALQGDTQAPKVSLGSTLLPTSESTATTPLYRIRQGQA
                     FTPKLKVWNNSGSIKSLDITGIPNGVTKHRFGTDFSEQTAATEMNPYSGSTLSGNVPD
                     TQAVGQHIAQITVKDASNNVATYYLKYEVYPARVEAKQGRFGQVKDKALIHGDDPANY
                     IKFKSANGKEVQKPADVKVTWERKPSTVEAGLNKTGLVKVTYHVTDENGVVRDEVQTV
                     TINTPVYHATLVQNPFKTTYGREFVNKNQPRDGRRYIDYNGRSHFNLSNLRVYWESSN
                     IRGQQFSDGTRPWPTNYLGKKREKLMVRYPGDNGRYDNRNDDYGARYEELDGTFIVKP
                     VKPNIQTSLGKVGKNTLTVNNVNSGTTVVVYDAANPNNLKELGRTMVAKEGDYRIKNG
                     VEVPLNSGVTFKKDQKIVTKVIYKITDDDQRTESDVSDIWTVKESLIANGIHVIKGES
                     YTGTAKDRIRYNDNVDAEQRTGLPNNATASWAQNPNYTTLGTSNYTANVTVPGQGSAT
                     VNVPVHVYAPANLKATSYNNKQGTLSNGANPENYIEFKDGNTVVTKPNNVTVRWQGGV
                     APRINTPGHNRGVIEVVYPGNAGASSTVVKTFTVQLPTYHTTATATEYTRTIGENFAK
                     TTARDYATTHNWNVGGSQYVWKNDETANREYSAENWGKVNGDWLGKKKNKVKVYYGND
                     NGSNSHSENLAEETEEITFVTKPKTPSITATALNGKAGQRNQQVTVNNVTPGTTVELY
                     NGDTKIGSVDVSKANNEAYTDIKTVTVAVNGQLPLSSNIRAKTIYMPNNANEKVESDF
                     STSVQSTTEGPQAPEISQNPENLLVKATVGQGGSTKVTLTYTDANGRVKEVGFTKNGQ
                     FWDKDDANADTTVSITNESNGTGEIQLQPGTAQEGTTVTVKQKTATSEFSTPATTKAL
                     GRLNGLTNVAQADGSVDITVPDTATKFDLTYRNQQNNTTETLHYSKDAQGRWGNVTGI
                     TADGNRFTLPKGLVTDGTTVSVIASNDNKTTKTVTSDAKFEMPDATTHTQRENGDGVI
                     TLPSTADSVTVTYTDAQDTAKTVTVTKNASNQWASTAALPEGVTLNGNELNVAYKNIN
                     SNGNVKTVSTRGTGNVRSQEAVENIELNHIPISTQAVVIAAGATPTNDDLGRGVTFAK
                     RSITAKSTPAAVPAGTSAEIPATLTYNDGSTEDVTITVKSKPTAPSFNNLENHGTYSG
                     LSSISKVISGTAMPGAEKVKLTLQDGTVKEITPQADGSWSYTLGATEYLTQSFSGQFN
                     GVFNQNKVKAVQVKDGVESEETTANVAPGQATVDSVYKAGRAITVNIPHDIEAGYVRV
                     NGTDYGIQKVNGTWRVISTAPNAAKLEISNTVVDPTNKAVTKVTFSVKNNDDALYTPP
                     FKIGNSPVRFRTYYSKNGTINTPTPQIRGTDGWADSPTPKNTKPTVNFTADHTIEENK
                     VFASPTVEELKDYFEGHDAEDDASLTVGYSASNRGKLRVQVFTQDTNQSVRANTQGRI
                     DPGNYRLVLSTNDAADAESEPITRNITVKTYADVYRDKVLYPTNVDKVTYDDTAISNG
                     NFTTAAKTSFKDKIQELNGTVLPASTRYTVGTTDDKAKVAVINFPDGSTIDISHAVVA
                     KPTVPTVTRTHADKVSDADRTISGTALQSATKVTIYFQDGRGEQGHADVVPVNGQWTY
                     TLPTGRYLRQTEHTSLPGSSSVPVNVTQTVFDATSDKTAVYVAKDRNFTGKQIVGTKG
                     SQELTALKNDAKKGINYTERNTPKDFPSDFDATWKETPDITTVGTRTYTAKVFEKDKG
                     DAVSQEISVEVTVKADTPDAVAASYKQNGDAVLTPPTNADKVTITYTNQAGAQQTVKL
                     SKTGGNWSVTEGDGTVLSGNQVVLPYKGLDRTQVIGTSATAGSDKYMSEVASQDYTVP
                     EHRVTIAPIIRSNSDTLLSTAVEDAVTVTNKENVEKQGNLPTGIGKHTINAKVTYKDQ
                     SEEMVEIPYTIKPDAPSISTSIGTAGKNSVTVNNVTPGTTVVVYDMTNPNNPIELGRK
                     DVSGATADAAQNGVTVSTNATLRKDTPIAAEVIYKPTVAAERISSDKSSSLVVKEGLA
                     VNSIHAVKGENYTGDLASRIHYNDGQDTGLPAGSTVEWKNNQAPDYNNVGTSRYTLVV
                     NVPNQGTTEIEVPVHVYPTASLKKASYTNKQGTLSNGTDASKYVQFEGSADTPNNVTV
                     RWKDGVPDVSTVSADRKAKIEVVYPGNASATDTVVKELEVSLPTYHSTAKSTEYTRTI
                     GEAYASTDASDYVETTPNTPRGTEYAWKTDETGNQAYGSSTWGGANGDWLGKKTNKVK
                     VYYPNADGGNEKSEVLAEETEEITFITKPAKPSITSDLTWASGTRTTVEVGNVTSGTR
                     VVLYDEQGNELGHTDVAKGANYATPTTASITPTKALPTGKVYVKTIYMPDTADQRVES
                     EKSDEATAKTNTLTAKGIIQTLAGPGNIGGVGTLDAATLGKLLRQENGGTDFTGATAE
                     WKDKTNLEKGNGGSRVEHLLVQLKGHSEKQDVAITVTSLTPPSAKAVLKSKGADLTND
                     NLADYVTAEGQGTLSWEGNPAKVEVGQALPRIKVTYPTTGVAITDITDQYVDAKVYSL
                     EANSNAKTRVTVGDAFDPSAGDYVQTVANTADLPRTGVSHAWKDGNKPTSATVGKATY
                     TVVTSFGNDADVPAELRGQDVETQVEVTVLSTKPSKPEASQNRTDLSITVVVGKDDAT
                     KAEITFKDELDQEHTVSFTKGANGQWDKDDANSQPTVQIINNADGTATVHMTGGTAKA
                     GSTVVTKQQKADSDFSDISELVVKEHLKGATVTTKDDGSVEVVVPKEADTATVSYVPE
                     GQTQAKTVTITKGQDGNWTGPADSDLVIKKDDATGRVTVTVPADKVADGSTVTGRVDS
                     ATGLSPEVEVKGKAPQPSEFSHHVRDNGDEVITLPQNADSVTLNYPVSDANVKTVTIS
                     KGQDGTWTAPADSDLVVKKDDATGSVTVTVPADKISGNRTITASAKAGSGDGESKERT
                     FTTTVVERQAPTVSEVTVAANGTLSAEQINAAVTAPKKVSAVAAEALKQVAAGSNTEI
                     PVTVTYADGSTETVQLAVYSKQVTPSTVGFQQKDNGDAVLTPPTNADKVTITYTNQAG
                     AQQTVKLSKTGGNWSVTEGDGTVLSGNQVVLPYKGLDRTQVIGTSATAGSDKYMSEVA
                     SQDYTVPEHRVTITTLVKPFEQNVTDKDLLDAVNADHKKSAKLKDGTSYPTTDGFHDI
                     DLTVTYEDGSMENVSVKYKVTDTAKADIDTAAAEKKTAIEKTPNLTPEEINVAKRQVD
                     EALAEAKRKVGEATDQAGINRAKQEGLSSIDLVLDQALVQSFGRTNGRRSRRTPPRRS
                     RRSVGFVGNSQTGTTPSAVDKSELRTLVEDLERRLKELEGLSPEAQSILREAQAALAN
                     DSLTAQELAKLLAKVRQALNSIQAGTSADKSPSTSNSNKEAESAKEPTNATDVPLYGV
                     FGAAALSLLGALLFAVARKKNSQLDKLLRELDQLLVELEASDKDKKGLGKAKKLAKKA
                     RTFVDSQQKDPQKEAELISEIKTTLSQLREGV"
     gene            complement(11156..>11984)
                     /locus_tag="VU722_001944"
     CDS             complement(11156..>11984)
                     /locus_tag="VU722_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1772847.1"
                     /translation="KHDFSCLPEIMAWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQ
                     AIIRNHFLRYDRAVLCRVKIITMDMFIPYYDLARQLFPCAKIVLDRFHIVQHLSRAMS
                     RMRVQIMNQFHRKSHEYKAIKRYWKLIQQDSLKLSDKRFYRPTFRMHLTNKEILDKLL
                     SYSQDLKYHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIV
                     NALQLPYSNAKLEVTNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         4097 a         2402 c         2739 g         2746 t
ORIGIN      
        1 ggagctgtgg cagcgagtga aacgattact ccaactacgg caagtgatgt cgttaaggca
       61 ggttctgatg gcaatgcaga tggaaatcca gcgtcctcgg atgagggaga ctccaagcaa
      121 gctctgactg acaaaccagc tgaactcaaa gcagctgatg agctgaaaac gcaagaagcg
      181 ccagctgagg gagccaatca aacaagtagt actggaatcc tccagccgcg gacgctcaaa
      241 aacaatcagt ctgactacga ccctattcca attgaggatg atgaggatga cgtaagagat
      301 gggctgtttt cttcggaaaa tccagtaacc actatccaac cacggagctc tcactctgta
      361 accggtcgcg cacttcaagg cgacacacaa gcgccaaaag tgagtttggg cagtactctt
      421 cttccgacta gcgaaagtac ggctactacg ccattgtaca gaatccggca agggcaagct
      481 tttacaccga aattaaaagt ttggaataac tcgggatcta tcaaaagctt agatataacg
      541 ggaataccga atggagtgac caagcataga tttggaactg acttttcaga acagacggca
      601 gctactgaaa tgaatcccta cagtgggtca acacttagtg gtaatgtgcc agatacacaa
      661 gcagtaggac aacatatagc tcaaattact gtaaaagatg catcgaataa tgtagctact
      721 tactacctaa aatatgaagt ctatccagca agagtagaag ctaagcaagg tcgatttgga
      781 caagtcaaag ataaagcctt gatacatggc gatgatccag ctaactatat caagtttaaa
      841 agcgctaatg gaaaagaggt tcaaaaacca gcagatgtaa aggtgacgtg ggaacgtaag
      901 ccaagtacag tagaagcagg tcttaataaa acaggactag taaaggttac ctaccatgta
      961 acagatgaaa atggtgtggt tcgagatgaa gttcaaactg taacaatcaa tacccctgtc
     1021 tatcatgcaa ctcttgtaca gaatcccttt aaaacaacct atggtaggga atttgtcaat
     1081 aaaaatcaac ctagagatgg tagacgctac attgactata atggaagatc tcatttcaac
     1141 ttaagcaatc tacgtgttta ctgggagagt tctaatataa gaggtcagca attttctgat
     1201 ggtacgcgac catggcctac caattattta ggtaagaaac gtgagaaatt gatggttcgc
     1261 tatccaggtg ataatggcag gtatgataat cgtaatgatg actacggtgc acgatatgaa
     1321 gaactagatg gaactttcat cgttaagcca gtcaaaccaa acattcaaac cagtcttggt
     1381 aaggtaggaa aaaatactct gactgtcaat aatgtcaata gtggaacaac agttgtggtc
     1441 tatgatgctg ccaatccaaa caatctcaag gaattgggtc gtacaatggt tgctaaagaa
     1501 ggggattaca ggattaaaaa cggagttgaa gtgccactaa actctggtgt aactttcaaa
     1561 aaagaccaga aaattgtcac caaggtcatc tataagatta cagatgatga ccaacgtaca
     1621 gaatctgatg tcagtgatat ctggacggtc aaggaaagct tgatagcaaa tggcatccat
     1681 gtcatcaagg gcgagagcta tacaggaact gccaaagacc gtatccgtta caacgataat
     1741 gtagatgcgg aacagcgaac aggccttcca aacaatgcca cagcaagctg ggcgcaaaat
     1801 ccaaattata ctactttggg aacaagcaac tacactgcca atgtaacagt gccagggcaa
     1861 ggaagcgcga cagttaacgt gcctgtgcat gtctatgcac cagctaacct gaaggcaact
     1921 tcttacaata acaagcaagg taccctatca aatggtgcca atccagaaaa ctatattgaa
     1981 tttaaagatg gaaatacagt tgtcactaaa ccaaataatg tgactgtgcg ttggcaaggt
     2041 ggtgtagcac ctcgaatcaa tacaccaggt cacaatagag gagttattga ggttgtctat
     2101 ccaggaaatg ctggagcaag ctctacggtt gttaagacct ttacggttca attaccaacc
     2161 taccatacaa cagctactgc tacagagtac actcgtacca ttggcgaaaa ctttgccaaa
     2221 acaactgctc gcgactatgc gactacgcat aattggaatg taggtggcag tcagtacgta
     2281 tggaaaaatg atgaaaccgc taatcgtgaa tacagtgcgg aaaactgggg caaggtcaat
     2341 ggcgattggc ttggtaagaa gaaaaataag gttaaggttt actacggaaa tgataacgga
     2401 agcaactcgc attctgaaaa tctagccgaa gagactgaag aaatcacctt tgtgactaag
     2461 ccaaaaacac caagcatcac tgcgacagct cttaatggaa aagcgggtca acgcaatcaa
     2521 caagtgacag taaacaatgt cacaccaggg acaacagttg agctctacaa cggtgatacg
     2581 aaaattggtt ctgtagatgt atcaaaagct aataacgaag cttacactga cattaaaact
     2641 gttacagtag cagttaatgg tcagttacca ctttcatcta atattcgtgc aaaaacgatt
     2701 tatatgccta ataatgcaaa tgaaaaagta gaatctgatt ttagtactag tgtgcaaagt
     2761 acaacagaag gtccacaagc gccggaaatt tctcaaaatc cagaaaactt attggtgaaa
     2821 gcgactgtag gacaaggagg ttctactaag gttactctta cttatacaga tgctaatgga
     2881 cgtgtgaaag aggttggatt cacgaaaaat ggtcaattct gggataagga tgatgccaac
     2941 gctgatacta ctgtatcgat tactaatgag tctaatggaa caggtgaaat tcaacttcaa
     3001 ccaggtacgg ctcaagaggg aacaacagta acagttaagc aaaaaacagc tacatcagaa
     3061 tttagtactc cagccactac taaagcttta ggacgcttaa atggcttgac gaatgtagct
     3121 caagcagatg gttcggtaga tattactgta ccagatacgg ctacgaagtt tgatttgacc
     3181 taccgcaacc agcaaaataa tacaactgaa acacttcact atagcaaaga cgcccaagga
     3241 cgttggggaa atgtgacagg cattactgct gacggcaatc gctttacctt gccaaaaggt
     3301 ttggtgactg acgggacaac cgtttctgtc atcgcatcaa atgacaataa gacaactaag
     3361 acggttacga gcgatgctaa gtttgaaatg ccggatgcta caactcatac tcagcgtgag
     3421 aatggtgacg gtgttattac gcttccaagt actgctgact ctgtgacggt cacttatacg
     3481 gacgctcaag atactgctaa gacggtcact gtgactaaga atgctagcaa tcaatgggca
     3541 agtactgctg ccttgccaga aggtgtgact ttgaacggta acgagctcaa tgttgcttat
     3601 aagaatatca atagtaacgg aaatgtgaaa acagtttcga cacgtggtac tggcaatgtt
     3661 cgttctcaag aggctgtcga aaatattgaa ttgaaccata taccgataag cactcaagcg
     3721 gttgttatcg ctgctggtgc gacaccgaca aatgatgatt taggacgtgg tgtgacattt
     3781 gccaaacgtt ctatcactgc taagtcaaca ccggcagctg ttccagcagg aaccagtgca
     3841 gaaattccag ctaccttgac ttataatgac ggctctactg aggatgtcac tattactgtt
     3901 aagtctaaac caacagcacc aagcttcaat aatcttgaaa atcatggaac atatagcgga
     3961 ttatcctcta tttctaaggt gatttcaggt acagctatgc caggtgcaga aaaagttaaa
     4021 ttgactttac aagacggtac agttaaagag ataactcctc aagctgatgg aagttggtct
     4081 tatactttag gagctactga atacttgacg caaagcttca gtggtcagtt taacggagta
     4141 ttcaatcaaa ataaggtaaa agctgtccaa gtgaaagacg gtgtagagtc agaggagact
     4201 acagcaaacg ttgcaccagg tcaagcgact gttgattctg tttataaggc aggacgtgcg
     4261 attacggtca atatccctca tgatattgaa gctggttatg ttcgtgtcaa cggaacagac
     4321 tacggtattc aaaaagttaa tggtacttgg agagtaatct caacagcacc aaatgctgcc
     4381 aaattggaga tttcaaatac agttgttgat ccaacgaata aagctgtcac taaagtgacc
     4441 tttagtgtta agaataatga cgatgccttg tatactccac catttaaaat tgggaatagt
     4501 cctgtaagat tcagaacgta ttattctaaa aacggaacca ttaacactcc aacacctcaa
     4561 attcgaggga cagatggatg ggctgattct cctacaccta agaacactaa accaactgta
     4621 aacttcacag ctgatcatac aatagaagaa aacaaggtgt tcgcttctcc aactgtagaa
     4681 gagttgaagg attattttga aggtcatgat gctgaagatg atgcaagttt aactgtaggt
     4741 tactctgctt ctaatagagg taaattacgt gttcaagtat tcactcaaga cactaatcaa
     4801 tcagtaaggg ctaatactca aggacgtatt gatccaggta attacagact tgtcttgtct
     4861 acgaatgacg cggcagatgc agagtctgaa ccgattacaa gaaatatcac agtgaaaact
     4921 tatgctgatg tttatcgtga taaggttctt tatccaacga atgttgataa ggtgacttat
     4981 gatgatacag cgattagtaa tggtaacttt acaacagcag ccaaaacaag ctttaaagat
     5041 aaaattcaag agctaaatgg cacggtgctt ccagcatcga caagatatac agtaggaact
     5101 acggacgata aggcgaaagt cgctgtgatt aacttcccgg atggttctac tattgatatt
     5161 tcgcatgcgg ttgtagccaa accaacagtg ccaacggtaa ctcgcacaca tgctgataaa
     5221 gtatcagatg ctgacagaac aatttctggt acagcccttc aaagcgcgac aaaagtaact
     5281 atttatttcc aagatgggcg tggtgaacaa ggacatgcag atgttgtgcc tgtaaatggt
     5341 caatggactt acactcttcc aacaggacgt tatctccgcc aaacagaaca cacttcatta
     5401 ccgggttctt cctctgtacc tgtaaacgta acacaaacgg tatttgatgc aacaagcgat
     5461 aaaacagctg tttatgtggc gaaagaccgt aactttacag gaaaacaaat cgttggaact
     5521 aagggtagtc aagaattgac tgctttgaaa aatgatgcta aaaaaggaat caactatact
     5581 gaaagaaata ctccaaaaga ctttccaagt gattttgatg ctacatggaa agaaacacca
     5641 gatattacaa ctgtaggaac aagaacttac acggctaagg tgtttgaaaa agataagggt
     5701 gatgcagtta gccaagaaat ttcagttgaa gtcactgtca aagcagatac tccagatgca
     5761 gtagcagcaa gctacaaaca aaacggggat gccgtcttaa ccccaccaac caatgcggac
     5821 aaagtgacca tcacgtatac caaccaagct ggagcacaac agaccgtgaa attgtctaag
     5881 acaggtggca actggagtgt aacagaggga gacggaaccg ttctttcagg taatcaggtt
     5941 gttctaccgt acaagggact tgatcgcaca caagttatag gcacaagtgc cacagcagga
     6001 agcgacaagt acatgagtga agtcgcaagt caggactaca cagtgccaga gcatcgtgtg
     6061 acgatagcgc caatcattcg ctcaaacagc gacacgcttc tctcaacagc agtagaagat
     6121 gcagtaactg taaccaataa agagaatgtt gaaaaacaag gaaaccttcc aaccggaatt
     6181 ggaaaacata ccatcaatgc caaggttact tacaaagacc aaagcgaaga aatggtagag
     6241 attccatata ctatcaaacc agatgcgcca agcattagca caagtatcgg tacagcgggc
     6301 aaaaatagtg tgacggttaa taatgtgact ccaggcacga cagtagtagt gtatgacatg
     6361 acaaacccaa acaacccgat tgaattggga cgcaaggatg tgtcaggtgc tacagcagat
     6421 gcagcgcaaa atggagtgac ggtttcaacc aatgcgactc taagaaaaga tactccaatc
     6481 gcagccgaag tgatttacaa accaacagtt gcggcagagc gtatcagttc agacaagagc
     6541 agtagcttgg tagtcaaaga aggtttggca gtcaacagca ttcatgcggt taaaggagaa
     6601 aactatacag gtgacctagc ttctcgtatc cactataacg atggacaaga cacaggtctt
     6661 ccagctggtt caactgttga atggaagaac aaccaagcgc cggactacaa caatgtagga
     6721 acaagtcgtt atacacttgt agtaaacgtt ccaaatcaag gaactacaga aatagaagta
     6781 ccagtccatg tttacccaac agcaagcttg aagaaggcta gctacaccaa taaacaaggt
     6841 actctgtcaa atggaacaga tgcaagtaag tatgttcaat ttgaaggtag cgcagatacg
     6901 ccaaataacg taacagtacg ttggaaagat ggtgttccag atgtctctac agtctctgca
     6961 gaccgtaagg ctaagataga agttgtctac ccaggtaatg cttcagcaac agatacagtt
     7021 gtgaaagaat tagaagtatc acttccaact taccattcaa cagctaagtc tacagagtat
     7081 acacgtacca ttggtgaagc ttacgcttca accgatgcgt cagactatgt agaaaccact
     7141 ccaaacacac caagaggaac ggaatatgca tggaagacag atgaaactgg caaccaagcc
     7201 tatggctcat caacttgggg aggggcaaac ggtgactggc tcggtaagaa gaccaataag
     7261 gttaaagttt actatccaaa tgcggatggt ggcaatgaga aatctgaagt cttggcagaa
     7321 gagacagagg aaatcacttt catcaccaaa ccagccaaac caagcattac aagtgacttg
     7381 acatgggcaa gtggtactag aacgactgtc gaagttggca acgtgacaag cggtacacgg
     7441 gtagtcttgt atgatgagca aggtaacgag ctcggacata cagatgtagc caaaggagct
     7501 aattacgcaa ctccaaccac agcaagtatc acaccaacca aggctctacc gacaggtaaa
     7561 gtctatgtga agacgattta catgccagac actgcagatc aacgtgtaga gtcagagaaa
     7621 tcagatgaag cgactgctaa aaccaatacc ctaacggcta aaggaattat ccaaacgctg
     7681 gcaggcccag gtaacattgg aggagtcggc acgcttgatg cagctacttt aggtaagttg
     7741 ttgagacaag aaaatggtgg tacagacttc acaggagcga ctgcggaatg gaaagataag
     7801 acaaacttag agaagggcaa tggaggaagt cgagtagagc accttcttgt ccaactaaaa
     7861 ggacacagtg agaaacaaga tgtggctatc acagtcacaa gtttgactcc gccaagtgcc
     7921 aaagcagtct tgaaatcgaa gggtgcagac ttgacaaatg ataacttggc agattacgta
     7981 acagcagagg gacaaggtac cctaagttgg gaaggtaatc cagccaaggt agaagtgggt
     8041 caagctcttc cacgtatcaa ggttacttac ccaacaacag gtgtagctat tactgacatc
     8101 actgatcaat atgtggacgc caaagtctac agtctcgagg ctaacagtaa cgccaagaca
     8161 agagtgacgg tgggagacgc ctttgaccca tcagcaggag actatgttca aacagtcgct
     8221 aatacagcag acttaccaag aactggcgtc agtcacgcat ggaaagatgg caacaaaccg
     8281 acatcagcga ctgtaggaaa agccacctac acagttgtta caagttttgg taatgatgca
     8341 gacgtaccag cagaacttcg aggacaagat gtagaaacgc aagtagaagt aacggttctc
     8401 tcaaccaaac caagtaaacc agaggccagc caaaaccgta cggatttatc gataacagta
     8461 gtagtcggaa aagacgatgc gacgaaggcg gaaatcacct ttaaagatga actggatcaa
     8521 gaacacacgg tcagcttcac taagggagcc aatggtcaat gggacaaaga tgatgccaat
     8581 agtcaaccaa cggttcaaat catcaacaat gcagatggaa cagcgacagt tcatatgaca
     8641 ggcggcacag ctaaagcagg cagcactgtt gtaacgaaac aacaaaaagc cgattcagac
     8701 tttagtgata tcagtgagtt ggttgtaaaa gaacacttaa aaggtgccac agtaactact
     8761 aaggacgatg gttcagtaga agtggtagta ccaaaagaag cagatactgc gacagtcagc
     8821 tatgtcccag aaggacaaac gcaagcgaaa acagtgacga ttaccaaagg tcaagatggc
     8881 aactggacag gtccagccga ttcagactta gtgattaaga aagatgatgc gacaggtaga
     8941 gtcacagtca ctgtaccagc agataaagta gccgatggca gcacagttac aggaagagta
     9001 gacagtgcta ctgggttaag tccagaagtt gaagtgaaag ggaaagcgcc acaaccatct
     9061 gaatttagtc atcatgttcg agacaacggc gacgaagtga ttaccttgcc tcagaatgcg
     9121 gacagcgtga cgcttaacta tccagtaagc gacgcgaacg tgaagacagt tacgattagt
     9181 aaaggtcaag atggcacctg gacagctcca gccgattcag acttagttgt taagaaagat
     9241 gatgcgacag gcagcgtcac cgtcacggta ccagcagata agatttcggg taaccgaacg
     9301 attacagcaa gtgctaaagc aggaagtggc gatggagaaa gtaaagaacg tacctttaca
     9361 acaacagttg tagagcgtca agcaccaact gtttcagaag tgacagtagc agcgaatggc
     9421 acactaagtg cagaacagat caatgcggct gttacagctc ctaagaaagt tagtgcggtt
     9481 gcggcagaag ccttgaagca agtagcagca ggcagtaaca cagagattcc agttacagtt
     9541 acctatgcgg atggctcaac agaaaccgtt cagttggcag tatactctaa acaggtaaca
     9601 ccaagtacag tcggcttcca acaaaaagac aacggggatg ccgtcttaac cccaccaacc
     9661 aatgcggaca aagtgaccat cacgtatacc aaccaagctg gagcacaaca gaccgtgaaa
     9721 ttgtctaaga caggtggcaa ctggagtgta acagagggag acggaaccgt tctttcaggt
     9781 aatcaggttg ttctaccgta caagggactt gatcgcacac aagttatagg cacaagtgcc
     9841 acagcaggaa gcgacaagta catgagtgaa gtcgcaagtc aggactacac agtgccagag
     9901 catcgtgtga cgataactac attagtcaaa ccatttgaac aaaatgttac agataaagat
     9961 ttgttagacg ctgtaaatgc tgaccacaaa aaatctgcta agttgaaaga tggaactagc
    10021 tatcctacaa cagatggttt ccatgatatt gatcttacag tgacatatga ggatggtagt
    10081 atggaaaatg tatcagtcaa atacaaagtt acagatactg caaaagctga cattgatacc
    10141 gcagctgctg agaagaaaac agcgattgag aagactccaa acttaacccc agaagagatt
    10201 aacgttgcga aacgccaggt agacgaagct cttgcagaag cgaaacgtaa agtaggagag
    10261 gcgacagacc aggcaggaat taaccgagcg aagcaagaag gcttatctag tatagatctg
    10321 gttctggatc aagctttggt tcaatctttt ggtagaacta atggtagaag aagtcgcaga
    10381 actcctccgc gccgctctcg tagaagtgta ggatttgtag ggaattccca aacaggtaca
    10441 actccatcgg ctgtggacaa gtctgaactt cgtactctgg tagaggatct ggaacgccgc
    10501 ttgaaagagt tagaaggtct atctcctgaa gcacagagta tcttgagaga ggcgcaagcg
    10561 gctcttgcta atgactcctt aacagctcaa gaattggcga aactccttgc taaagttaga
    10621 caggctctta attctataca agctggcaca tcagctgata agagtccgtc tacgtcaaac
    10681 tcaaataagg aagcagaaag cgccaaggaa cctacaaatg cgacagatgt ccctctatat
    10741 ggtgtctttg gagctgcagc actctctctt ctaggagctc tcctctttgc agtggctcgt
    10801 aagaaaaact ctcaactaga taagctttta agagaattgg atcaacttct agttgagtta
    10861 gaggctagtg acaaggataa aaaaggttta ggcaaggcta aaaaattagc taagaaagca
    10921 agaacctttg tggatagcca gcaaaaagat cctcaaaaag aagcagaact aatttctgaa
    10981 atcaagacta ctctcagtca actcagagaa ggagtctagt cttgaagaaa aaaactactt
    11041 tcaaaaatgc agtgagtagt tttgtagcga tgatgaggaa ataaaaggct ctttgtcaac
    11101 tgtagtgggt tgaaaaaaac tggctctttg tcaactgtag tgggttgaaa aaaaactaag
    11161 ctcgagaaag gacaaatttt gtcctttctt ttttgatatt cagagcgata aaaatccgtt
    11221 ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat
    11281 tattggtcac ttccaatttg gcgtttgaat agggtagttg aagggcgttg acgattttct
    11341 ctttgtcctt tagaaaggtt ttaaagacag tctgaaaaat aggatgaacc tgcttaagat
    11401 tatcctcaat aagtccgaaa aatttctctg gttccttatt ctgaaagtga aacagcaaga
    11461 gttgatagag ctgatagtga tatttcaagt cttgtgaata gctcaaaagc ttgtctaaaa
    11521 tctctttatt ggttaaatgc atacgaaaag taggacgata aaatcgctta tcactcagtt
    11581 taaggctatc ctgttgtatg agcttccagt agcgcttgat agccttgtat tcatgggatt
    11641 ttcgatgaaa ctgattcatg atttgaacac gcatacgact catagcacgg ctaagatgtt
    11701 gtacaatgtg aaagcgatcc aacacgattt tagcacacgg gaaaagttgt ctagctaagt
    11761 catagtaagg gataaacata tccatagtaa tgattttgac gcgacatagg acagctctat
    11821 cgtagcgaag aaagtgattt cgaatgatag cttgtgttct tccctcaaga acagtgatga
    11881 tattgagatt gttaaaatct tgcgcaatga agctcatctt tccctttgta aaagcatact
    11941 catcccaagc cataatctca ggaagacaag aaaaatcatg ttta
//
LOCUS       DAVFJR010000054        11894 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVFJR010000054 DAVFJR010000000
VERSION     DAVFJR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.055"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VU722_001945"
     CDS             complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VU722_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU1772848.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1414..1485)
                     /locus_tag="VU722_001946"
     tRNA            complement(1414..1485)
                     /locus_tag="VU722_001946"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1451..1453),aa:Gln,seq:ttg)
     gene            complement(1495..1575)
                     /locus_tag="VU722_001947"
     tRNA            complement(1495..1575)
                     /locus_tag="VU722_001947"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1539..1541),aa:Tyr,seq:gta)
     gene            complement(1625..1855)
                     /locus_tag="VU722_001948"
     CDS             complement(1625..1855)
                     /locus_tag="VU722_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU1772849.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VU722_001949"
     CDS             complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VU722_001949"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU1772850.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDVVLCIGQAGGRIGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYLSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2682..3605)
                     /locus_tag="VU722_001950"
     CDS             complement(2682..3605)
                     /locus_tag="VU722_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU1772851.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3602..4291)
                     /locus_tag="VU722_001951"
     CDS             complement(3602..4291)
                     /locus_tag="VU722_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU1772852.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4434..5033)
                     /locus_tag="VU722_001952"
     CDS             complement(4434..5033)
                     /locus_tag="VU722_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1772853.1"
                     /translation="MACGKTDKEADAPTTFSYVYAVDPASLDYSIATRTSTTDVIGNV
                     IDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQEPASYLNIMDPKSGSAMKHLGITKGK
                     DKDVVAKSGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMPTASFGGSPV
                     VSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYN"
     gene            complement(5116..6138)
                     /locus_tag="VU722_001953"
     CDS             complement(5116..6138)
                     /locus_tag="VU722_001953"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU1772854.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAQFKNGQWNQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVIRANEEYVPPYGTGGTLYLRPLLIGIGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTDFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPVEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTCKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VU722_001954"
     CDS             complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VU722_001954"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU1772855.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDLFSTEVEENDQTLLVQSNKGTIYENRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLKEVFTEAK"
     gene            complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VU722_001955"
     CDS             complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VU722_001955"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU1772856.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLVAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRREWIEDNVKFTLEEATVF"
     gene            11243..11884
                     /gene="plsY"
                     /locus_tag="VU722_001956"
     CDS             11243..11884
                     /gene="plsY"
                     /locus_tag="VU722_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU1772857.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3418 a         2692 c         2091 g         3693 t
ORIGIN      
        1 aaaaatccct tgtttagtaa acaaaggatt ttgtgaattt tcaatttgat taaagttcga
       61 tatcaccaaa caaatcagcc attgaaaatc ctgtttgtgt ttctggaagt tcgaaatcac
      121 gcttttcttg acgtcttgga cgacgtggac gagcagcacg tttttcttct ttttgtcctt
      181 cttcttgggc tggacgttct tcaagagctt taatagaaag tgacacgcgt tctgcatctg
      241 cgttaacttc aagaacttta acttgaactt cttgaccaac tttaagagct tcttttggat
      301 tttcaatccg tttgtgtgaa atttgtgata cgtgaacaag tccatcgata cctggcaata
      361 cttcaacaaa tgcaccgaag tcagtcaaac gtttaactgt tccttctact acatcacctt
      421 tagccaattt ttgctcaacg ccatcccatg gtcctggtac tgttgcttta agtgaaagtg
      481 atacacgtcc ttcttcttcg ttaagatcaa ggattttcac ttcaatttct tcaccaacag
      541 ttacaactga ttttggtgat acgttacgtt catgtgacaa ttcagtcaag tgaaccaatc
      601 cgtcaacacc accaaggtcg atgaaagcgc cgaagcttgt gatacgagca actttaccag
      661 ttacaacatc accaacagcc aatttaccga atacttcagc gcgagctgct gcagtagctg
      721 cttcaacaac ttcacgacgt gaaaggatga agcggttttc tttagcgtta acttctttga
      781 ttttagtatc aaattcttga cctacaaaac gctcagcgtt acgtacgaaa cgagtatcca
      841 acattgaagc tgggataaat ccacgaacac cttcaaattc tactgaaagt ccacctttaa
      901 cggcacgcgt tcctttaaca gtaacaactt cttcttcgcg accaacaagt ttgtcccatg
      961 ctttgcgagc ttcaaggcgt tttttagata caaggtatgt aactgtatca gtatctttac
     1021 caactacttg acgaagtaca agaacatcca atacttctcc tactttaaca aagtcattga
     1081 tatctgcatc acgatcgttt gtcaattcgc gaagagtcaa gacaccttca acaccagttc
     1141 cagagattgc aacgttagct tgagtcgcat caactgtcaa tacttcagca ctaacaacat
     1201 caccagtctc aacttgacta acgctattta gcaaatcttc aaattcgttc atctaaaaaa
     1261 tcctccaaca atcaagtttt tcttaaactt gacatactta taattttttt cctaagcacc
     1321 cgcaaggaca tgtttatatc attcacgtct ttcaattata aaaataaaat accctaagat
     1381 attttgcttt ttatcttgat tattacctaa gaactggggt agctggattc gaaccaacgc
     1441 atgagggagt caaagtccct tgccttaccg cttggctata ccccattaat gaaatggaga
     1501 gagagggatt cgaacccccg aacccgaagg agcggattta cagtccgccg cgtttagcct
     1561 cttcgctatc tctcctacaa tcaacatgga ctattatatc atgaaaattt caaaaaaaca
     1621 agacttattt tgctaaatta taattttcaa tcaaaatttc cacagctttt tccaattttt
     1681 tataaaaact atcgacattc ccattcttta taatggcaaa ttgtccgtct aattcggcaa
     1741 tttctccgat aactttttta ccgatagtca atgtataacc ttcaaaactg tctttaccaa
     1801 cattaacttt ggcatccgct acttgaattt cgattttttt atctttcttg ctcatttcat
     1861 acctctcttc actttttcta ttttacaaga aaatcctaaa actagcaaga aaaaactcta
     1921 tatcaggctt ctctgatata gagttttatg taaacaacct caatcgattt agcatagtta
     1981 atagttagta aacaagcata attgactatc ctttttaggt tatcagtgag tctcaccgcc
     2041 tactaactgc aaatccttat ctttgtagtc tacaatagct tcaatagcta cctctatgcc
     2101 tcttacaata tcacatagac tcattcctgc agtattcggc ttatttacta cttgttccat
     2161 catatatgga atatgcatga aacctgctct catattaggg aattttttat ccactaaata
     2221 aagagcttgg tacatcaaat gattgcaaac aaaggttcct gcactattgg atacaactgc
     2281 cggaagtccc tgttttttga tagcttgtac catcgctttg ataggtaaac tacttaaata
     2341 ggccgatgct ccatcaatac gaatcggtgt atcaattggt tgattgcctt cgttatcagg
     2401 tatgcgagca tcatcttgat taatagccac tcgttcaggt gttaagccga tcctgccgcc
     2461 tgcttgtcca atacaaagta caacatctgg ttgatatcgt aatatttctg cctctaaaac
     2521 ttctgacgac ttataaaaaa ccgttggaat ttctacccag cgaacttcag ccccattaat
     2581 ctcagatggt aataatttta cagcctccaa agctggatta atcttttcac ctccaaaagg
     2641 attaaaacct gtaaccaata ttttcatttt attttccttt actaaaatgc gagaaagtac
     2701 attaagaata tgtgaataac aatcattact agagcaacac ctgcttgagc ctttataacg
     2761 ccattctgat ctttcatatc catcaatgct gctggtagag cgttaaaatt agcagccatt
     2821 ggggtcaata aggtcccaca ataacctgct gtcatggcaa gagcaccagc cacaattgga
     2881 ttagctccca gagcaaatac aaagggaact ccaacacctg ctgtaataac ggtgaatgct
     2941 gcaaaagcat ttcccataat cattgtgaat agaaccattc caagaacata ggccaaaact
     3001 cctataaagc gactatctga aggaacaata ccgctaatca gatgagagat aacatcacca
     3061 acacctgcta cagtaaaaat agcccccaaa gcccctaata attgaggaac aatcccactt
     3121 gttgaaactt gctgagtcat tcgattattt tctgataaca gactcttagg gtgactattg
     3181 gtaatcacaa gaacagaaat tgtagcaaac aaggcggcaa ggctaatcga aatcttgcta
     3241 aattctggaa tcatttgcgc taagaccaac gcaagtattg ccatcagcat aactggaata
     3301 aaaattttat ttttcaacct gttagattca atattggctt tcatttcatc taaggatggc
     3361 aaggttccaa tacggacttg cttaaacaat gttaacagcg ataataggat tacaataata
     3421 ccaatactca tatttggcat ataggaacca cctataaacg taatagacaa tagagtccaa
     3481 aatgcagatg tcccaagtcg aactgggttt gttttatctt tataactaca ataggctgta
     3541 tggagaaatt gacaaccaat cacaatatag gtcaactcta atagttgctt tgccaactct
     3601 gtcatttttg ttctcctccc ctagtctttt ttgatatcaa ttttttatca aataaataat
     3661 tgtaaatccc tactacaata agtgttataa cagcaacaat aatagatgta gaagcaatcc
     3721 ctgcataatt gctttcatag cctaactgat ctaatgttcc ccctatcaag aggactcccc
     3781 cagcacctac aaacgtattt tgagcaaaga aatttccaaa attttcattc gcagccgcac
     3841 gcgcttttat tgtctcatct tcaacctctg ttaactttct acctaattga gactctgcag
     3901 ctgcttctcc cataggttga accaaaggtc tgacaaactg agggtgtcct cctagacgaa
     3961 ttgaaaagaa accagctaac tctcgaataa agaaataaac tgtatagaag tttccaactg
     4021 tcagaccttt aatctttcga atcaaatcga ttgatcgttg cttgagtcca aaggtttctg
     4081 acagccccac aagaggcaag gtaaccataa aaatcgtgag cactcgctga ttgctaaatt
     4141 cttttcccaa aatctccaaa aattcaacga gagaaacacc tgaaactaaa gctgtaacca
     4201 aaccagctaa gactactgtt gcaattgtat caaattttaa aataaaaccc acaacaataa
     4261 ttgctattcc tattaatcta atccactcca tatcaaactc ctttatattc aaaatgacag
     4321 tatttttaaa attttatcaa gatcaatacc attccttatt taatgtgttt ttctagttct
     4381 ttttggtatt tgctattgga ttccaatttt tctttttgcc attttttaaa aacctagtta
     4441 tattcttttg ttgtaacaat atctttttgc aatttcattc ctttaaagat atatggatcc
     4501 cccttaatac caacttgtga gtatggtttt gagaatggta ctacgttact tacaactgga
     4561 gaaccaccaa atgaagctgt tggcatcaat aatgaactat ctgtcgacca agcttgagct
     4621 ttggcatatt tttcatatct cttctctagg tcagtagtct cagaaacagc atcttctaac
     4681 aatttcttat atttatccaa accagattta gctacaacat ccttatcttt tcctttcgta
     4741 ataccaaggt gtttcatggc agaaccagat tttggatcca taatattcaa gtaagacgct
     4801 ggttcttgat agcttggagc ccatcctgta ctgttcaaat catagtcttt ttgagaagga
     4861 gcaacattgc cgtatttatc attttccatc aagccatcaa taacatttcc aataacgtct
     4921 gtcgtcgatg ttcgagtcgc tatactgtag tccaatgatg ctggatctac tgcatagaca
     4981 taagaaaatg ttgtcggtgc atctgcttct ttatcagttt ttccacaagc cactaaaata
     5041 gctgtcgtgc tcaggaccgc tcctgctgtt aagagtcact ttttcgattt cataaaaaat
     5101 ctattttggt ttattttaat ctacttttac aatccaacct tctggcgctt caatatcgcc
     5161 aaactgaata cccgtcaatt cattatataa tttacaagtc acaggaccta cttctgtttc
     5221 actatagaat acatggaaat catcaccgtg ttgaatacct ccaattggag aaataaccgc
     5281 tgctgtacca caggcacctg cctctacaaa acggtcaaga ttatcaattg gaacatcacc
     5341 ctcaacagga gttaatccca agcgatgttc tgccaaataa agcaaggaat acttggtaat
     5401 agatggcaag atagatggac tcaatggtgt tacaaattca ttatcagctg taattccaaa
     5461 gaagttagct gatccgactt cttcaatctt tgtatgagtt gatgggtcca gatagataac
     5521 atctgagaaa tgacgtgact tggccatttt tcctggtaag agacttgcag catagtttcc
     5581 accaacctta gccgcacctg taccatttgg tgctgcacgg tcgtattcat cctgaatcaa
     5641 gaagtcggtt gggaccaaac cacccttaaa gtaatttcca actggcatag caaagatagt
     5701 aaaaatatac tcctctgctg gttttacccc gataatatct ccgataccaa tcaaaagagg
     5761 gcgaagatag agggttccac ctgttccgta tggtggtacg tattcttcat tcgcacgaat
     5821 aactgcttta caagcttcta caaacatgtc tgtcggaact tgtggcatca agagacggtc
     5881 acatgtacgt tgcaggcgtt tggcattttc gtcaggacgg aacagttgaa cactgccatc
     5941 cttagtacga taagctttca aaccttcaaa tgcttgttga ccatagtgaa gacttggaga
     6001 agactctgaa atatgcaaag ttgcatcctc tgtaagttct ccttgattcc attgtccatt
     6061 tttaaactga gcaagatagc gataaggtaa tttcatatag gaaaaaccga ggttttccca
     6121 atcaatcgtt actgtcatat tccactcctt attctaaaaa cctatttctt atattctaca
     6181 ctatttttct aaaatagcaa gtctgttttg taattttcag aaaatttctc caataacaag
     6241 aaccagctct tagaactgat tcttcatttc acttatttag cttcagtaaa tacttcttta
     6301 agataagcgt caaaaacttc ttcatctgaa atcgtgtcag aaatgaagct tccgttgcta
     6361 gtcctttctg acaggttcaa gtcttgcaat ctgttttcat agattgttcc tttgttggat
     6421 tgaacaagca gcgtttggtc gttctcttct acttctgtac tgaagagatc gccaacaaat
     6481 ccttgctctg caactgctcc tgccaagaag acacgatgcg gtttgttttt caactcacgc
     6541 aagacttgta atcctcgttt ggcacggctg gttgctagaa tttcctcaat ggaaacacgt
     6601 ttcaagcttc cacgctgggt caagaggtag aaggacgaag tattacagat aaagccagat
     6661 tggaggacat catcttcttt caaattcata gccttgacac ctgctgcctt agcaccgaca
     6721 accggaacct cttcgatatt gaaacgcagg gcataaccat tttgactaac caagacaaca
     6781 tcatctagtt taatcggagc cactgctaca atctgatctg tatcgtcttt gagcttagca
     6841 tacttgacag acttagatct ataggtccgc catggagtga attcttttcg ctctacccgt
     6901 ttgatttgac caaggcgagt cactgcaaag taggttgtcg catcgtcaaa ctgatccagt
     6961 acttccacat aaaggatttc ttcattcgtt tcaaagtttg tgatggtttg gctcagatgc
     7021 tctccgatgt ccttccaacg aatatctgcc aactcatgga ttggtctgta gatgacattt
     7081 ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg cagattgaac aaaaatcaaa
     7141 cggtcatcat cacgcttgcc aatttcttcc aaggtggaag ccgcaaagga acgtggactg
     7201 gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg tatcttcctc agcgataaga
     7261 ctagctgtat caatctcaat tgctttcgca gtgtcttcta aagaactcaa acgaggagtt
     7321 gcaaatttct tcttgacctc acgaagttct ttcttcatga gattgtacat agtcctttca
     7381 tcaccgataa tagccgccag catagcaatc ttctcacgaa gctctgcttc ttcttcctgc
     7441 aagacaacca catcggtatt ggtcaaacgg tacagttgca aagttacgat agcctcagcc
     7501 tgttcttccg taaaatcata gctaactttg aggttttcct tggcgtccgc cttattctca
     7561 gaagcacgga taagagcaat gacttcatcc aaaatcgaaa tcacacgaat caaaccttcg
     7621 acgatatgga gacgtttctc agccttttct ttgtcaaagc gtgaacgcgc caaaatcact
     7681 tctcgacggt gagcgatgta gctagacagg attggaacaa tcccaacctg acgaggtgtg
     7741 aaattgtcaa tcgccaccat attaaagttg tagttgattt gtaggtcggt gtacttaaat
     7801 aagtaattga gaacaagctc agtattagcg tctttcttaa gttcaatagc gatacgaaga
     7861 ccatcacggt cagactcatc acgaacctca gcaatcccag ctaccttgtt attaacacga
     7921 acatcatcga ttttcttgac tagattggcc ttattgattt cataaggaat ctcagtaata
     7981 acgatttgtt ccttaccacc ttttagcttt tcaatttcag tcttggaacg aacaaccacg
     8041 cgccctttcc cagtctcata agctttcttg atttcatcac gaccctgaat aatagcccct
     8101 gtagggaagt ctggtccagg taagaattcc atgagtttat caatctttgc agttgggtgg
     8161 tcaatcatgt aaactgcagc atctatgacc tcagctaaat tatggggagg aatgtctgtg
     8221 gcataaccag ccgaaatccc agtcgaacca ttgaccaaga ggtttggaaa ggctgctggc
     8281 aagaccgttg gttctttctc cgtatcgtca aagttccatg caaaaggaac tgtctttttc
     8341 tcgatatcct gaagaaggta gcctgcaatt tcagacaaac gtgcctcagt ataacgcata
     8401 gctgcaggag gatctccgtc catagaaccg ttattaccgt gcatttcaac tagaatctca
     8461 cgatttttcc agttctgtga catacgaacc atggcatcat agatagaaga atccccgtgt
     8521 gggtggaaat tccccatgat gttcccgact gacttagccg acttacggta gctcttgtca
     8581 aaagtattgc tatccttatt catagaataa agaatacggc gctgaaccgg cttcaaccca
     8641 tcacgaatat ctggcaaagc ccggtcttga ataatgtact tggagtagcg accaaagcgc
     8701 tctcccatga tgtcctccag ggacatgttt tgaatgttag acataagata caaagcccat
     8761 aaaataccaa gtaaaaatag aaaattcttg aagtaagcaa actcacaaga gaatttatct
     8821 ttttcacaca gtatctaggg cgtgttcaac tcctttcaaa gaatgtagag taggttttta
     8881 tgcagtaaaa gatattttac gggaattcct cccgtgttca gttacgataa gtaaccaaac
     8941 tatcctgttt gtatttttca atatgaaaat ctggttttcc aaaattagtc ttagtttgtg
     9001 tcttagccgc tcccttaagc gcctctttga gataagcact catagcagat tcttcattaa
     9061 taatcctgca attttttcaa accaagattt tcaaactgct ttttcacata gtcattcaca
     9121 tccgactcta atttccagtt tactaacata ttattttctt tcattaaaac actgtcgctt
     9181 cttctagcgt aaacttgaca ttatcttcaa tccattcacg gcgtggttct accttatctc
     9241 ccatgagaac attgacgcgg cgttcggcgc gcgctaaatc ttcaattgtg acacggatga
     9301 gggtacgtgt ttctgggttc atggttgttt cccagagctg gtccgcattc atctcaccaa
     9361 gtcctttgta tcgttggagg gtagcgcctt taccgaactg tttacggagt tcttctagtt
     9421 ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc tttacctttg gacatcttgt
     9481 aaagaggtgg gagggcaata tagacatgac ctgcctcgac tagcggacgc atgtaacggt
     9541 agaaaaatgt caagagcaag gtctggatat gggcaccgtc ggtatccgca tcggtcatga
     9601 taatgatctt atcatagttg gcatcttcaa tagagaagtc tgctccaaca cccgcaccaa
     9661 tggtataaat catggtattg atctcttcat ttttgaggat atccgccatc ttggccttgg
     9721 ctgtattgac aaccttacca cgaagaggta gaatagcctg gaacttgcgg tcacgacctt
     9781 gtttggcaga accaccggca gagtccccct caactagata gagttcattc ttagcaggat
     9841 tcttagattg ggctggggtc aatttcccag acaacaagcc cttatctttc ttgtttttct
     9901 tcccatttcg gctctcatca cgcgccttac gtgctgcttc acgagcatca cgggccttga
     9961 tagccttgcg gatgaggtta gaagctaatt ccccattttc cataaggaaa aaggtcaact
    10021 tatcagccac tattccatcc acaactgggc gagctagggg gcttcctagt ttatccttgg
    10081 tctgtccttc aaactgcaag tgttcttcag gaactaagat agaaagaacg gccactagtc
    10141 cctcacgata gtctgaacct tcaaggtttt tatctttttc cttaagaaga cctgttttac
    10201 gtgcatagtc attcatgacc ttggtaatgg cagacttgag tcctgtctcg tgcgttccac
    10261 cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt atctgagaat ccgtcattgt
    10321 actggagggc tacttccact tgaaaaccat tgtcttcccc ttcaaagtaa agaactggcg
    10381 tcaagatttc cttatcttcg ttgagataag aaacaaaatc ttgtactcca ttctcatagt
    10441 ggaactcaat cgcttcatct gttcgcttgt ccgttaaaga caaggtcaca tttttcaaga
    10501 gaaaggctga ttcattaagg cgctctgaaa tggtattgta cttgaaatct gtcgtagaaa
    10561 agatagtcgc gtcaggcata aaagtaactt tggtgcctgt tttagacttg ggtgctgtac
    10621 cgattttctt caaagtcgtg acaggttttc caccattttc gaaacgttgc ttgtaaactg
    10681 cgccatcacg ggtaatttca acttctaacc agctagaaag ggcgttaaca acggaagaac
    10741 ccactccgtg aagtccacct gatgtcttat agccaccttg accgaatttc cctccggcat
    10801 gaagaatggt aaagataacc tcaacagttg gaattcccat agcgtgcata cctgtcggca
    10861 tcccacgtcc atggtcttga accgttagac taccgtcttt attgatagtt acatcgatac
    10921 gatcaccaaa cccagacaag gcttcatcga ctgcattatc aacgatttcc caaactaggt
    10981 gatgaagacc agcgccatcg gtcgatccaa tatacatccc tggacgtttt cggaccgcat
    11041 ccaacccttc tagcacctga atagcatcat cattataatt gttaatattg atttcctttt
    11101 ttgacacaag gaacctccta ttcgttcatc tttactattc tacaggtttt ccaaggattt
    11161 tgcaaaattt ttctttctcc gatgtgacaa tttcagcaga gattctctgc ttttctttcc
    11221 caattcatga tataatagga gtatgattac aatagtttta ttaatcctag cctatctgct
    11281 gggttcgatt ccatctggtc tctggattgg acaagtattc tttcaaatca atctacgcga
    11341 gcatggttct ggtaacactg gaacgaccaa taccttccgc attttaggta agaaagctgg
    11401 tatggcaacc tttgtgattg actttttcaa aggaacccta gcaacgctgc ttccgattat
    11461 ttttcatcta caaggcgttt ctcctctcat ctttggactt ttggctgtta tcggccatac
    11521 cttccctatc tttgcaggat ttaaaggtgg taaggctgtc gcaaccagtg ctggagtgat
    11581 tttcggattt gcgcctatct tctgtctcta ccttgcgatt atcttctttg gagctctcta
    11641 tcttggcagt atgatttcac tgtctagtgt cacagcatcg atcgcggctg ttatcggggt
    11701 tctgctcttt ccactttttg gttttatcct gagtaactat gactctctct tcatcgctat
    11761 tatcttagca cttgctagtt tgattatcat tcgtcataag gacaatatag ctcgtatcaa
    11821 aaataaaact gaaaatttgg tcccttgggg attgaaccta actcatcaag atcctaaaaa
    11881 ataaaacgcc agtt
//
LOCUS       DAVFJR010000055        11254 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVFJR010000055 DAVFJR010000000
VERSION     DAVFJR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.056"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..1129)
                     /locus_tag="VU722_001957"
     CDS             complement(<1..1129)
                     /locus_tag="VU722_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1772858.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANV
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIIL"
     gene            complement(1209..2072)
                     /locus_tag="VU722_001958"
     CDS             complement(1209..2072)
                     /locus_tag="VU722_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU1772859.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFYNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(2075..3976)
                     /locus_tag="VU722_001959"
     CDS             complement(2075..3976)
                     /locus_tag="VU722_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1772860.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFCQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATVEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(4402..4677)
                     /locus_tag="VU722_001960"
     CDS             complement(4402..4677)
                     /locus_tag="VU722_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU1772861.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4784..5623)
                     /locus_tag="VU722_001961"
     CDS             complement(4784..5623)
                     /locus_tag="VU722_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1772862.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDIEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKNHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5764..6612
                     /locus_tag="VU722_001962"
     CDS             5764..6612
                     /locus_tag="VU722_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU1772863.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6705..7622)
                     /locus_tag="VU722_001963"
     CDS             complement(6705..7622)
                     /locus_tag="VU722_001963"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU1772864.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            8060..8265
                     /locus_tag="VU722_001964"
                     /pseudo
     CDS             8060..8265
                     /locus_tag="VU722_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8576..8869)
                     /gene="rpmA"
                     /locus_tag="VU722_001965"
     CDS             complement(8576..8869)
                     /gene="rpmA"
                     /locus_tag="VU722_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU1772865.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8886..9230)
                     /locus_tag="VU722_001966"
     CDS             complement(8886..9230)
                     /locus_tag="VU722_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU1772866.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(9246..9560)
                     /gene="rplU"
                     /locus_tag="VU722_001967"
     CDS             complement(9246..9560)
                     /gene="rplU"
                     /locus_tag="VU722_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU1772867.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9596..9683)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9742..10305)
                     /locus_tag="VU722_001968"
     CDS             complement(9742..10305)
                     /locus_tag="VU722_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU1772868.1"
                     /translation="MTFCAGYVNAYTFIVRGNTLVAGQAGNVVFLSVDLIQNNVSDVR
                     DKLLTLIAFIMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIAFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILG
                     VPIMMSVFYLSMLFASWQKKVKEKASF"
     gene            10776..11075
                     /locus_tag="VU722_001969"
     CDS             10776..11075
                     /locus_tag="VU722_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU1772869.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3566 a         2325 c         1882 g         3481 t
ORIGIN      
        1 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
       61 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
      121 gtactctccc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagtgaatat
      181 taaaaatcgt cataaacaat tcacaaacta aatttccaga aaaggaaaga aaagttggaa
      241 gtggtaatcc catcataaaa actccgacac ctgtcaaagc cagtaaaatc aaaagattat
      301 aaacattagc tttaatttta ctagctagaa gagccccaat gatggaacca atagccccca
      361 tagttaaaat acttgcatag gctccttctg acccgtaaag ctgattcgaa aagggaagta
      421 gaaattcaaa agctgcaaaa aagaaattaa cgctggaagc taccagcaaa aggaagaaaa
      481 tttcttgctg atgccagata tagtgtaacc catccttgat atctacaaaa atatctctcc
      541 cagtaaaagc ctttttctct tgaacttttg cttcctcttt tggaaggaaa gccactagaa
      601 caaaagcaat gaaaaaagtc agcgagtcta gcagtagcgt catatggaga cttgcaaact
      661 gtaaaacaag gaaggaaaga acaggagagc tgacacctac aacctgcaaa accagctcta
      721 ggcgagaatt atagatcaca atctcatctt tctccaccac ttcagttatg atagctttat
      781 tggctgtgcg agaaaaggca aaagcaatag cctgcacaat gttagcaaca atcaaagcgc
      841 caatcatcca gctatcattc cttatgaaag aaatagccag acaaagaatc ccacaaacaa
      901 gatctgccgt cattaaaatc ttacgacgag aaaaacggtc tgaaataact ccgccaaagg
      961 gattgacgag aatagatgtg acgagctcag aaatctgata cattcctaaa actgtctgtc
     1021 ctatagtccc catagaagcc aaccagacac tatttccata atcatagagc atatttccca
     1081 ttttattgat agccccacgg ctaatcaact gcactgcata gcgattcata ttaaagctcc
     1141 tctcaaattt tgaaactatt gtatcaaaac cgaaaggagc tttttatttt ttcccttatt
     1201 tgggaaaatt aacttttgac aaatttttcg tagtgttcct gataataggc tacttgctcc
     1261 ggaagaccta acacatcaaa aatatgcatg gcctcttgca tctgcttaca gccttcttta
     1321 cactgtcctt tttgatataa ggcaaaacct tttaaataat ggaaaacatt acgctcataa
     1381 agcttaatac ctttgtcaat aatcttctct gtataagcct caaaatagtt ggcattataa
     1441 aaagaagaat gctctaaaca atgctggtaa caatttaggg ccaaaatcaa aactaatctc
     1501 ttatggcgac taatctcttg gtaaaattcc tccctctcca taacttctct accaatccga
     1561 gtgacatagt ctacatcgta gaaactatag aggttaccga aaagaatcaa ctcatacatg
     1621 gtccattctt ctgttttgaa gagataatct gctaccttat ccaaatcatc ctgcttcata
     1681 tcataactcg catctctttg acaaatcaga ccttgtagca aaatccagtt cagctcaaaa
     1741 taaaggggag tcgtcgaact cttagacttt tcaagttgtt ctctttgaag cttttgaaaa
     1801 cctgcaatat cgtttgaata gtaaagtggg ataatctgtg ccatcataga cacatgttca
     1861 tgattataaa aattccttgc cttatccatg aaattttcga ttgttacatg aatattatcc
     1921 aaaatctcaa agaaacggga gactgccagg tcagactccc caagctcaaa acgagataac
     1981 tgagaggtag agcaggattc gcctgctgct tcctttaaag aataatttcc acttgttcga
     2041 aattcacgaa atacttttcc aagatgttcc atttttacac ctgctctgat aattcttccc
     2101 actcaagcat agcttcttcc tgacgatggc tgattttgtc cagctcagcc tgtaattcca
     2161 tgagtttgtc ggcatcgttt gtttccaaca tttgttcaga aatggcttgg ctttgacttt
     2221 ctagctcttc aatttcagct tctagacttt cgatttgtcg catgagtttg cgaacttctt
     2281 tttgactttc tttctgggcc tgatagtcat tgactggact tgcttccttt gcttgattgc
     2341 tagttgaagc ttcctcagtc tgactcattt ctactgttgc tttcttttca acatagtagt
     2401 cgtaatctcc aaggtagaga gttgaaccat tctcagacaa ttccaaaaca tgagttgcca
     2461 cacgattgat aaagtaacga tcatgactga caaaaagcaa ggtaccatca aagtcaatca
     2521 aggcattttc tagcacttcc ttactatcaa tatccaagtg gttggtcggc tcatccagaa
     2581 tcaaaaagtt attgttttcc atagacaatt tagctaaaag caaacgagct ttttcgccac
     2641 cagatagcat gccgactgat tttttaacat catctcctga gaaaaggaag gctccaagac
     2701 ggttgcggat ttcaacttct ggtgtcagtt tgaaatcatt ccagagttca tccagcaccg
     2761 tattacttgg tgtcagcttg ctttgggttt ggtcatagta accaacctca acattagcgc
     2821 caaagcgctt ttctcccttg ataaaaggaa tctggtccac aatagacttg ataaaggttg
     2881 acttgccgat accatttgga ccaacgatag cgacagcatt catcttacga agatctaggt
     2941 tgataggttg tgacaagact tccccgtcat aaccaatagc agtattttca acagtcaaaa
     3001 caacattgcc cgacgttttt tcagactgga aggtcatgtt ggctgctttc ttaccagctt
     3061 caggcttgtc caaacgctcc attttttcta gttgtttacg gcgagattga gcacgtttag
     3121 tcgttgaagc acgaactaga ttgcgattga caaagtcttc cagagcagcg atttccttct
     3181 gttgcttttc atagtttttt gcctcagtaa ctagcttttg ctccttcaat tcgacaaaac
     3241 gagagtaatt ccccacatag cgatccaagg aatgcttggt caaatctagc gtaattgtcg
     3301 caaccttgtc caagaaataa cggtcgtggc tgacgataat gagggcaccg ctatagttta
     3361 ccaagtaatt ctctagccag gcgatggttt caatatccaa gtggttagtt ggctcgtcca
     3421 agaccaagag attgggcttt tcaaggagca ttttggcaag tgccaaacga gtattttgac
     3481 caccagaaag ctcagcaatt ttcatctgcc acatagactc gtcaaacttg aatccattca
     3541 aaatcgctcg aatatcagct tcataggtaa agccacctgc ttggcaaaaa ttctcagata
     3601 agcggtcata atctgacatc agtttatcca aatcctcacc agacttttca cccatctcca
     3661 gctccatctg acgcagttgt ctctccgtcc gacgcaaatc attaaagaca tgaagcattt
     3721 catcgtagat ggtattttca gactcaaaac ggctatcttg ggctaggtaa gacagagaaa
     3781 tatctttttt cttattgatt tctccgctag ttggctcttc ttctccaact aaaatcttca
     3841 aaagagtaga cttacctgca ccatttttcc caacaagagc aatccgatct cgttcatcaa
     3901 cctgcaggtt gatattatcg aaaagaacct ctcctgcaaa agaacgttca attttattag
     3961 cttgtaaaat aatcataaga gtagtatagc atgtttccct aaggcattca agataatcgt
     4021 aagtctttta gtacaacttt tataacataa aataaactaa attatgtata ttttatatta
     4081 gattccttca ctatcttgtt ggattttcta accagctaat cttgtttcaa atagttatcg
     4141 cacaagtcta ttatttaatt cttttcatca tttacgtacg tatagcagat tgaaataaga
     4201 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4261 gtactatttt agattcagtc tactatatac aatattttcg gaacattcaa ctttttaact
     4321 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4381 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4441 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtggat tgcgaccttt
     4501 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4561 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4621 cttagtcaac tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4681 aatgattcct ccaaataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4741 ggtcaagtta aaaacgctat ttcttcccat tttatttatt tttttaggag tggtaacgta
     4801 tcaaaatagc ccaagcgttc tcacccgtgt gagtttgaat aatggaaccc gtttccaaaa
     4861 cagaaattgg cttttcaaca taagcttgta agctttcttt catctctttt gcccaatcat
     4921 cactaccaga atatgaaatt ccaatctctg ctacagcacg ttcagaaagc gatgttatca
     4981 actcatctaa ccatttttta aatgttttag ttccacgacc tttaaccatt ggctgcaatt
     5041 catggttttt catttgcatg acaacacgga tattgagaag agagctcaac aagccagtta
     5101 cacggccaat tcgtccacct ttgacaagat tttccaaagt tgaaacacca atataaagct
     5161 ctgtatggtt tttaacctct tctacatgag ataaaattgc ctctatatct ttaccttctt
     5221 gagctaactt cgcagcctca acaacttgga atttcagggc ttggtcagtg aaggaactat
     5281 caacaacagt cacatctgca gtagataggc tagcaccttg gcgtgctgct tctaccgtac
     5341 ccgaaagagc atgggacata tgaatagcaa gaatttggcc accatctttg cataggtctt
     5401 caaaaatctc agcaaagaca cctacaggtg gctgacttgt tttcggaaga ttcttacttt
     5461 cttgcatcaa ctgaagaaat ttaccttctt ctttcaaatc cgcatcagaa taaacaacat
     5521 tatcaatcat tacagataat ggaacaattg taatatctaa ttgctttact agttcaggtt
     5581 caatagtaac agatgaatcg gttacaatct taatttttgt catagtatca atctttctat
     5641 tttaggattc agattggttt ccttacttct aattatatca aaaaaaaatt aaaaatccta
     5701 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5761 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5821 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggcatt
     5881 accctcatca ccttttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5941 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     6001 ctaggaacct tagctttgtc cgcctggtta gctttttttg agcatattcc ccttcatatt
     6061 gatcttcaag gtgatttact aatcacagcc cttatagcgg gaatcctatt gggaattggc
     6121 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6181 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6241 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6301 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6361 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6421 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6481 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6541 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6601 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6661 ttgggttaca gacaacctct tttttgtttt atttattcaa gctcttaaga ccaattccga
     6721 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6781 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6841 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6901 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6961 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     7021 cgaccacgag cattaccatg aactaccata cctcttgatg gaagcggtgc ccccaaaagt
     7081 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     7141 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7201 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7261 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7321 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7381 cgttcagcag ggttcaaaat atgcaaaaac aaatctggat gataaggctc taaagcgatc
     7441 tttggagatt cattaaaggt cataacgacg ataggcaata aatcctttct cgcagccttg
     7501 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7561 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7621 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7681 ttttcacatg aagtgtacct gttttcaaaa ggcactttat tctatcgttg cttaactatg
     7741 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7801 ttagacttgt tcggtaacca taaagtgtca tactatgctt atgtatgaaa aagcaatgca
     7861 actaactcct gagaacttta aattactaat tggtgccgaa aaggtagaat ttagaatcga
     7921 ggtacaccta tggctgtaaa atttacaaaa tgagacaact tgggcaagat gtttgaagaa
     7981 tttcctaaac tccctgattt gaagcaagtc actttccctg atgacaaaga aaaaagccaa
     8041 agcaataaag aaaaactaga tgactgcttt ccaacaactc ccatctagtg tgcttcagac
     8101 tgggctattt ttctctccat ctgttagctt ggattctcag accgtttcag ctaaagaata
     8161 tcttttccct tatcagaagg aacggctcaa gccattcaga caagtgaagg gacgacaagc
     8221 caatatttga aaccagatag cagttcttat agtcaattga aataaaatct gaagaaatcg
     8281 agtaggaaac tcatatcaat gtttaacagt gttctattcc agattcatac tcaatgaaaa
     8341 ttaaagtgca aactaggaag ttagccgcag gctgtacttg agtacggcaa ggtgaaactg
     8401 acgtggtttg aatttgattt tcgaagagta tcaatccact atacatatta aaaagtatgg
     8461 gtatcaaaat aaaaaaacag gctctccgaa aactcggaaa gccttatttt aagctgtttc
     8521 tagcttcctc acctttacat ttcaaggttc gggataaaag gttcaatgaa cctttttatt
     8581 ttgcgattgg gtaaactgaa acttgttttt tatcgcgtcc tttacgttca aagcgtacta
     8641 cgccttcaac tttagcgaac aaagtatcgt ctccaccacg accaacgttt acacctggat
     8701 agatgtgtgt accacgttga cggtaaagga ttgatccacc tgttacagtt tgtccgtcag
     8761 ctgctttagc tccaagacgt tttgcttgtg aatcacgtcc atttgatgta gaacctccac
     8821 cttttttgtg ggcgaaaagt tgcaagttgt taagagtcat ttttaacata atgttttcct
     8881 ccgtgttagt tttctgtgat aactctggtt tggacgaact cagaagagtt ctccgataag
     8941 tttgccatac ctaagaaaaa tgattcaaag aataactggg tcatttctct ctggtgtgaa
     9001 ggaagatctt ttggtatttc aaccatcaga tagccacctt catcttcgtt taattctagg
     9061 attggttcat agcctgcaaa tttctcaata gaattgataa agttaatggc aagcgtagaa
     9121 accgatgcac acacgacatc taagccgtat tcgccactct cggcgtgtcc agtaatttcc
     9181 gcactcctca gctcgccatc ttcggctctc tcaaagactg cctgtatcat gtgttctcct
     9241 taaaattaag cgttgattgc gttgatgaca acttttgtat atggttgacg gtgaccttgt
     9301 ttacggtggc tacctttttt aggtttgtac ttgtaagtaa ccactttctt ttgttttcct
     9361 tgtttttcaa cagttccaac tacagtagct ccagcaacaa gtggagttcc gacaacagtg
     9421 ttttcaccac caacaagaac aacttcgtta aaagtaactt cttgaccagc ttcaacgttc
     9481 aatttttcaa cgtaaactgc ttgaccaact tcaactttaa cttgttttcc gccagttttg
     9541 ataattgcgt atgtgctcat tatgcacctc ctatgatttt tatgggtttc cccgattttt
     9601 tgtgaagact cgcctagcat cgtgggacga accacttaaa cttgaataat caagcaacga
     9661 tgttcgtgcg gttgcacagg atcgtgcata gtcaactctt caagtatagc atatctccta
     9721 ttttcttaca agtaataaca cctaaaatga agctttttct tttacttttt tctgccaaga
     9781 ggcaaaaagc atgctgaggt aaaaaacgct catcataata ggaacaccaa gaatggtctt
     9841 ttcatgatag aaaatcgtca aataggctga aaagacaacg ccaaggacaa aactactaag
     9901 caggctaaca aatatgaatc cttcacgcaa aaaaggagtg tgcttggttc ggaaataatc
     9961 tccaaaagca gttgtcacca gtcccataca gaaggccaag ggcggcacta gatagatatt
    10021 atccacagtt tgcggcacaa aagcaataat gattgataag attgccaagg gaatcaagga
    10081 cagaatagat tttttcacaa ttctcaattt ttccttataa atcgttaata aaaagactcc
    10141 cattataaac gctattaagg ttaaaagctt atccctaaca tccgaaacat tattttgtat
    10201 gagatctacc gaaagaaaga caacatttcc agcttgtcca gctacaaggg tattccctcg
    10261 aacaataaaa gtgtaagcat tcacatatcc agcacaaaac gtcaaaaaag tgctaacctt
    10321 ttagactgac gtgatatttt tcttataggt aataacctca ttttccctcc cattgtattt
    10381 tctcttagaa atattgtacc attttctttc taaaaaatcg caggctacca tttagatttt
    10441 actattagca taaaaataat aatagacaac tatttatcca aaaatagata gaggtaacat
    10501 gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact agaatagagc
    10561 ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac ataaataact
    10621 ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata cttgggcttg
    10681 atgactatgc tactaataac aattaggaga gaaaatcagg cacttgttaa caacaaggat
    10741 tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa aacatgatgc
    10801 gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt gctgctatgc
    10861 aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc gataagaaag
    10921 ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga agacctcgaa accctttctg
    10981 atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact actaagaaaa
    11041 aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga acaatacttg
    11101 tcgataacaa agactaagaa aggtgcaaaa attataggct ctataatatt tgtagtgggt
    11161 aaattcccta tggatattat ggagcctatt ttgtgtagaa aaaaagtccc atatgaccta
    11221 taatgaaaag cgacaaaaca actcattaga aaga
//
LOCUS       DAVFJR010000056        10833 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVFJR010000056 DAVFJR010000000
VERSION     DAVFJR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.057"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..483
                     /locus_tag="VU722_001970"
     CDS             <1..483
                     /locus_tag="VU722_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU1772870.1"
                     /translation="REIRNLEKMIKEIDKAIEDMVETIPEYQCLTSIPGVGKVYAAGI
                     IAEIGQIERFKDHPQVAKFAGLNWREKQSGNSNSQHTSLVNRGNRYLRYYLVEAANSV
                     RRYDDEYKDFYKKKYHEVPKHQHKRAIVLTARKFVRLVVVLLRNHQLYTPPRRLMEDN
                     "
     misc_binding    complement(726..943)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1026..3722)
                     /gene="ppc"
                     /locus_tag="VU722_001971"
     CDS             complement(1026..3722)
                     /gene="ppc"
                     /locus_tag="VU722_001971"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU1772871.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMNQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(3742..4971)
                     /locus_tag="VU722_001972"
     CDS             complement(3742..4971)
                     /locus_tag="VU722_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU1772872.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(5127..5353)
                     /locus_tag="VU722_001973"
                     /pseudo
     CDS             complement(5127..5353)
                     /locus_tag="VU722_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(5758..6654)
                     /locus_tag="VU722_001974"
     CDS             complement(5758..6654)
                     /locus_tag="VU722_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU1772873.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVLNDLILKWK
                     SEPKFVWAKNVINELNKTENGRSIIRRIATEFYKMKNISDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLKQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSSKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            complement(6705..9665)
                     /locus_tag="VU722_001975"
                     /pseudo
     CDS             complement(6705..9665)
                     /locus_tag="VU722_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(9662..10471)
                     /locus_tag="VU722_001976"
     CDS             complement(9662..10471)
                     /locus_tag="VU722_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HEU1772874.1"
                     /translation="MEKMHSYIKYLIHEDPIITDEGKQVEILHLDIQDDPEIFEDWAN
                     QFRRNYCSDDELAEMIGFMNISPKEYLKNFKLPSDSGIGLSTMSGDFGEILVSDYLQN
                     IEEYVVPRTRYDSRVNKDTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSQA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQENVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKKHRDFQKLRLLVIHSDELMKFIRELYSKASEV"
     gene            complement(10455..>10833)
                     /locus_tag="VU722_001977"
     CDS             complement(10455..>10833)
                     /locus_tag="VU722_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU1772875.1"
                     /translation="KGYEVQLALIATKPELSYLSTLIRYEELYAINPNQARATPKEHH
                     DFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTTSAATVLHDLLFGEWNTV
                     EKEMLKIGQERLWDMSKSNGKDA"
BASE COUNT         3431 a         2115 c         1612 g         3675 t
ORIGIN      
        1 agggaaattc gaaacctgga aaaaatgatc aaggaaattg ataaggccat tgaagatatg
       61 gtggaaacca ttcctgaata tcaatgcctg acctccatac ctggggtcgg taaggtctac
      121 gctgctggta tcattgccga aattggacaa atcgaacgct ttaaagacca tccccaggtc
      181 gcaaagtttg ctggtctgaa ttggagagaa aagcaatctg gtaactcaaa ctcacaacat
      241 acttcgcttg tgaatagggg caatcgttat ctgcgctact acctggttga agccgccaac
      301 tcggtaaggc gctatgatga cgaatacaag gatttctata agaagaaata ccatgaagta
      361 cctaaacacc aacacaaacg agccatcgta ctaaccgcta gaaaatttgt gcgtctggtg
      421 gttgtgctac tacgcaacca tcaactctat acgccaccaa ggaggcttat ggaagataac
      481 taagttatat ctgcacctct ccttgaaaat ctactgaaaa cagtgtgaaa acgtcgtttt
      541 cagcagggct tctttagtgc accctttttt tgaaatagtt ttcaaacttt gagcgggggg
      601 tcgcttgaca ttttaccact agactttgta tttcctttaa catatttcac ttatctaaac
      661 aagcgacgcc atcgttttct ttccatacta atctccatca aaaaaaatcc tcacacaagt
      721 ttttgtgtga ggacgtcgat gcgcggtacc acctcaatta tagggaattt ccctatcgct
      781 cagtctcgca ataacgagat gcactgtaag gtgtgctcac cgaattttta taatttcaaa
      841 ttctaaatag cattcagccc aattttcatc atcgccactt atctgttttc agctaccaca
      901 gactctctaa aaagtttgta tgattacttt tctgaatggt taaattatat catttttaaa
      961 ctacttgtca atagtctatt agaatttttt tgatattcac ttttagcatt cactcttgaa
     1021 aattatcaac ctgaattacg caatcctgtc gcaattccgt tgatggtgat atgaatcaat
     1081 cgttcttgat cactggacaa ttctccacga cgttggcgtt taatcaactc taactgaata
     1141 tagttgagaa tattaaagta aggcatacgg taatccaaac tagcttttag atatggattg
     1201 tcagctaaga gttcgtcatg tccttcaata gccaagataa cgttcttagt aacttgccat
     1261 tcatttaaaa tagtctcata gatggcctta acttgctcgt cttcacaaag tttagcatat
     1321 tcaaaagcaa tattcatatt tgattttgac aaaaccatat caacatttga aagaagcgat
     1381 tggaagaaag gccaattttg gtacatatct cgtaagatag caatattctc tggattttta
     1441 ttgataaatt ccttgaagct tgaaccaacc ccgtaccatc cagggaacat aacacgactc
     1501 tgtgaccatg agaataccca agggatggca cgcaaaccac cgatttcagt aatagtctta
     1561 cgagcggctg gacgagaacc aatattaaaa cttgaaatag ccttgattgg acttgactcg
     1621 aagaaataat catagaaatg ctcattacca aagaccaaat cacggtagat atcgtaacta
     1681 cggtccacta cttgattcat aatagcttca taacgatttg gggtattggt atcgctcttc
     1741 ttctgagtaa tcatacggtt aatagctgcc gatactagca tttcaaggtt atagtaagcg
     1801 gcgtctttgt taccgtattt attcccaatt acttcaccct gctccgtcaa gcggatacga
     1861 tccttgatag acttgagcgg ttgagatgta atggcttcat aggttggccc accaccacga
     1921 ccgacagtac caccacgacc atggaagaag gtaaccttaa cgccaaattc atctccaata
     1981 gcagtcaatt gttgttgagc cttgtagaga gtccaacatg aagacaagta accgccatct
     2041 ttattactgt cagagtagcc aagcatgatt tcttggtagt tatttcgtga gtcaatccat
     2101 tttttggcaa ggctaagaga aagatatttt ctcattgttt cctctgaatg atccaagtct
     2161 tcaattgttt caaaaagggg aacaatctga acacgagccc tttccgtatc caccagtcct
     2221 acttctttta acagaatagc taattctagc atatcagaaa gactggttgc atgtgaaatg
     2281 atggtctgac ggatgacatc atctcccaac ttatctttca aaacacgagc cgtcttaaaa
     2341 atagctagtt cttttgctaa taattctgat ttttctgcgt gagtcgcaga aagaattcga
     2401 ggatcttctt ctaattcttt caagagaagg tcacactttt cttcttcgct caactcgcta
     2461 taacgagaat gaattcctgc tgatttcaag agttctgcca cacaggcttc atagacgcta
     2521 gagtcttgtc gcatatcaat tgatgctagg taaaaaccaa atatctctac tgcctgcaat
     2581 aattccacaa aatcacctga aatcaaggac tcgcccttat tttctagtag agaatctcga
     2641 atggcaatca aatccttgta gaaatcattg gcggtttcat aacgagtccc aacttcttca
     2701 tcctcaatca gataggtttt agttgcctga atttttgatt gaatatcaaa caaggcacga
     2761 cggtaaagct ctttttcgcg gtaaatcgag ttatccttgg attgacgagc catttctctg
     2821 acttgcttgc tgacgttgac aatgctagtt gaaagagaaa attcacgata aagttggtaa
     2881 atctttttat catagtagtt catgatgact tcacattgag tgagtgcaga ctgcttcaag
     2941 gtctctgctg taacaaatgg atttccatca cggtcaccac ctatccacat acccatggtg
     3001 attggtttag cttgttttaa attcagacca tgcgcttgcg ctaagcgctt atactccgtc
     3061 gtcaaatgag gtacagcttt caaaaaggag ctgttataat attccatagc attcgtgatt
     3121 tcgttagtca cttttaattt tttctcacga atcatgtctg tctgcatgat aatttcgatg
     3181 taacgacgca aatcattgta ccatttatct ttattgatca accccaactt aacatcacgg
     3241 tatttacgca aaagactatg aatatgattt gttaaatcca acatactttt gcgttgcact
     3301 tgtgttggat gggctgtcaa aacagggaca acattcaagt gttctaggat ctcaacggca
     3361 ttttcctttt ctgctaccaa tttaatcgtt gtagataatt tacctaaata gtcctgatca
     3421 atattatttt gatgattgat ttcataagct aaatccacat cctctgaaat attaatcaaa
     3481 agaggtaaga tagagaaata gcgtgaaata tagaccattt catcatttga taagctagtc
     3541 actagacggt ttagaccttg ataatcttcc tgcgttgata attctttcaa ctgtattatt
     3601 ttttcaaagg tctctggggc aagcatattt ttagtaatat cttccagtaa ttctgttaga
     3661 atcaagactt cttcttgcac aacactttta ttactataat tttctaattt ttgaagagac
     3721 ataaactatc ctttctttat cctacttcaa cagaaggttc attggttgat tttccaattc
     3781 tcggtacaac ttagcgcgtt tttcactggc atcaatattt aagacaaagg ctactgccac
     3841 tgataagact agaagactat ttccaccctg ggataagaag gggaaagtca ctcctgtaga
     3901 tggaatcaag cccgaaatcc ctccgatatt gacaaatacc tgaaccaaca tcatccctcc
     3961 gacaccgagc gcaaccatgg cattaaaagg attctctgct cggatgccga ccaagataat
     4021 ccgcaaaatc atgaaaaaca agagagctaa aataagactg gcaccaacaa agccaaattc
     4081 ttcaatcacg atagaaaaaa caaagtctgt atgagcttct ggcaaataac ctcgtttttc
     4141 aatcgagttc ccaagaccta gaccaaacca accgccattg accatggcaa aataagaatt
     4201 agctaactgg tgacccgcat cagcacgatc ggcaaaagga ttaaaaaagg cactaaagcg
     4261 cttggctaca tagccaaata ctggaatttt tgaaaaggtc tcaacaccga ttaggctgat
     4321 agtggtcaag acaaagacag aagcggcaga tacgagcgcc agaatggttg aaaaccagcg
     4381 ataagcgatt ccactaactg tatacataat caaggaaacc aagactaaaa tagtcgcatt
     4441 tcctaaatca gggaaaatgc ccaaacttcc aatcagaact aggagaacga atcgccaatc
     4501 attaaaagca cggggaagcc attgattttg agtcaaaact tgaaaatcat aagtagctat
     4561 ttcttcttgc tgtttggaga atcggtgagc taaataccaa ataataatga tttttaagta
     4621 ctcagctggc tgaatagtta ctcctgcaac cgaaatccaa ccgtatgccc cgtttacgga
     4681 aataccaata aaacgagcca agaacaataa aagcatttct attaatataa ctaaaatgat
     4741 tagtcgctca tttctcaaaa aatctagtct caatttataa attaaggcaa tcagtatcaa
     4801 actaacaatc caaaagattc cttggtttcg aaccaactgc aaggcgctct tgccttcttc
     4861 aattaaaata gcactagtgg tcgaatagac cacaatcaag cccaaaatag ataaaagcaa
     4921 gtagggaatc aagatggaat aatttaataa gtgcctctta ctaatcttca tagcatcacc
     4981 actctactag gatacagaca aatctgttcc aaattccgtt ttattttcta gttttgattg
     5041 ctattatacc attttttcag aaagaaaaaa actcttacct tacaatcctt cgaattttac
     5101 tgtttttaca gaattaaggc agaatttgaa atcgtaaaac cattttgaac aagagttact
     5161 tcaacccatt ggctccgact aattaagttg ctttcgtgaa tgctaaaatc agccgcaatt
     5221 tgttcataag tgcgctattc tcgcatgtat tgaatagtta ccataaggag atcgtctagg
     5281 cttaatttgg gttttcgtcc accttttgcg cgtttacgtt gcgttgataa gctgttttta
     5341 acacagctaa catctcgtgc gctgaacacc tacaaggctc ttgaaacggc tatcgcttaa
     5401 ttgtttactt gcttcatcat ccatagtttt attgtattgt attgtatttt tgtttcgcag
     5461 gaagtctatt attcctttcg ttccaaggtt tttacgcttt tagcaacact acacactcca
     5521 cgtgatgcgt ctgtggaact caaaaggttc ggggaacctt ttgaggatta attgcgtttc
     5581 tctaacaaac tcacacattc aacgtggcat gactgatgaa gtcatcataa aaatttcact
     5641 tgctgctctt ttacgttggc agcctgaacg gtcagaagta tcattgtata tcatttgtat
     5701 catggcatat aaagtatcgc tctattttat tgatggtttt aatatctctc ggaaaagtta
     5761 ttcttgatta attatagaaa catttggatt gccagtttta gaagcaccaa ttatcttaac
     5821 ttttaaagct tcgtacaaac taattctatt ttctagaata taagctaatt cttgtccatc
     5881 cataaataaa attttagcat ctttattaga aaaatcttgt attacttcat ctctaaaacc
     5941 atttattgaa agaaacagtc cccgagtcga agttagtttt gtatcaactt tttgttttaa
     6001 agaagctatt ttcgaagaat ttactggatt tttttcccat ttcatttcaa ctaaataatc
     6061 aaaaccttca aacctaaaat agccatctaa ctgttgagta tttgttctat ttctatacga
     6121 atcatggtaa tcaatatcat taattctgaa taaattagca acaatttttt ctaaacgata
     6181 tcctctttct tgaggattat cacttgaaaa tagcgaataa tactccgtct ttagttcttc
     6241 aattttttga aggagttgtt gcttgagttg tattttcatt tcctgtcttg aacgatgata
     6301 agaattatta agtgtttcgt taaccttatt ctgttgagta tcacctatca gtcgctttaa
     6361 ttttcttaac gcatctaatc ctctatctct atcttgaact tcatcagaaa tatttttcat
     6421 cttataaaat tcagttgcta ttcgtctaat tatcgatctt ccattttctg ttttattaag
     6481 ttcatttata acatttttcg cccaaacaaa cttcggttcc gatttccatt ttaatattaa
     6541 atcatttaga actcccgaag tttgcataaa tgaaacgaca gtatctttat agtgaaaaca
     6601 taatccaaaa cattgaataa tttgttgttg gatttcaaaa gatattttag tcattttttc
     6661 tcctttctat caacaatatt acatttcatt aattatctgt gtataataac ttggaccaca
     6721 attctatctg aaaaacctaa ttcatagata ttgatttctt tttccagagg tagcccatat
     6781 ttcagcctct ttattaacat agtcaatacg tccaattcct ctccaactag tttttcaaga
     6841 atattattaa tcgcatttaa aaccattgat gtttcatacc ctaatccatt atcacaaata
     6901 gagattatgt cagacatatc aattggtttt gacttacctc ttttctcaat actaattgat
     6961 ttttcagtac aactttccaa tatttgaaaa taagaaatcc ccttaatcca gagttgagaa
     7021 atataattta gattttctat acttagtttt ctcatctctt tgttatttga aaaatctatt
     7081 attttcttgg ttaaaacacc taataactct tcttccttct cacaagaaat gatagatgtt
     7141 ttattttcct gaacccattc ttttaataac tcagattgat ataatccaat tgagtttttt
     7201 gcaattattt cagtttctac tgaactggta attattttag attttatcaa gataaataat
     7261 tcttttattt tttctttttc ctcttcatta ttacctaaga aatatccaaa tgtattttca
     7321 gctaaactat cagtctccaa ttcagtagca tacatagaag caatataatt ttcaattgca
     7381 attagggtat tatcaatctg gtctatctta gaattaaaat ccttaaaata aagactgttc
     7441 tttcttttta attttgataa aatattattt atttttgttc tgtagtctac agaactgtca
     7501 aatctctctt taatcaaatt ccaaaaatca aattttatag gagcgaatcg ataatcagtt
     7561 ggaactactg atttaaactg tataatactg agaatattac tttgacaacc ctctgtatta
     7621 ataggattta acaatgcttt atagttttgt tttttccact tattttttgg tgatttataa
     7681 atattgggct ctgttaaaat tattgttcct tctgtatatt ttccagccct tcctgctcta
     7741 cctatcaaat tctgaaaatc acgaactttt attgcatctc ctgcttgata cacacttgag
     7801 ataatcaagt atttaatagg taagtttata ccttgtgcta aggttgaagt acatactaca
     7861 ttatttattt tactttttga aaaagcatac tctatagcaa tgcgtatccc cataggtata
     7921 cctgaatgat gtgaaaaaac tcctagctga ctacatgtat attcaacact atcatatcct
     7981 aaattttgac caattaaatt tcctattttt tcaacttcag acctatctga gttttttaag
     8041 aaatcagtta gatcataatt tctattattt aagtctataa atcttcgtaa aataacattg
     8101 accgtgtctt ttcttccaca aaaaattcct actccaccat tattaattag attaatccca
     8161 taataaatac ttatatcatt ttcgtttgtc agttctggaa aaactttttg tttgcgttct
     8221 tttccaagct gctctaattc actaacacta acagtacgtg gaacaaaaaa ttcttcttca
     8281 aatgtaatag gatctatgaa atataattgc tcattactcc cgtttaaatc actaaacgca
     8341 actcttttct ctgttgtttt aatcgaatta ttagaaacaa ttactccatc ttcgttaaac
     8401 caccgattta tagcttcact atttggtatt acagcagata ttaaaatctt ctgtattcct
     8461 tttgggaaaa tttgtttaac cgttgacaac agtaattcaa aatttgttcc acgacttgga
     8521 tcatcaaaaa gatgtgcttc atcaaatata caaagtccta tttcatcaat aaaactttga
     8581 tgatttctca ataaaaacaa caattttcct ggagtaagta taaaaactct ttttttacca
     8641 tcattaaaaa ttgagaaatc ctgtggaatc tccggtaaat caaaaacttc actaacaatc
     8701 acattattct catcaacgaa atgtgcatta atatcacgat atatttctct acataatgct
     8761 ctaaaaggtg caacaatcaa tgcattatca attctatttg aataaaatgc tgatcttaag
     8821 gttagattga ttgaggctgt tttacccgaa cttgttggca tctgaacgat tccagattta
     8881 cctgaaaaaa ttgcttgctt ccctaattcg atttgagatg gccaaagctc ctttatactt
     8941 cctgttgatt gtatataatc ctgccataaa gaaaaatcta atcctgaaaa ttcaggtaat
     9001 aatttcgttg atgaactatc tattttttta catacaactg ctaagagaca atttacaatg
     9061 attacagaaa aatcgcttcc attcctatat actttatctt gtaaatctct ataaatatct
     9121 atagaaaact cagtttttga taaaatataa tttctatatg attccaccag agtatttaac
     9181 tcactagagt atttaccttc tattggcgta tgattcaaaa agagtttatc tgtaataaca
     9241 ttaataaata cttttacaag agttatactc tcttctaata actgcatatc atccgatatg
     9301 tagttaacca taactctcga actaccatta taatcgccta gataataagc tgtggtacct
     9361 agtattgcaa tatagtcttg atattcagct gaatttccta atcctgacac cagcaatgca
     9421 tcaaaatatt cagcaacatt gtgtaattga ttttttaatt gtgaatcaaa actcttatga
     9481 ttgatataat cttcaaaata cttcctagca gtatctgcag caattgctaa tgccccaaga
     9541 aacgattttt gagcatcctc agaaattgga atatgacttt ctaaaggaat ttcaaattca
     9601 atcatctttg cctttgaacg cactaatttt gaaaaatata atgacttttt cccaaattct
     9661 atcatacctc actcgctttc gaataaagtt ctctaataaa tttcattaat tcatcagaat
     9721 gaatgaccaa tagtcgtaat ttctgaaaat ctctgtgttt ttttgaaact actgtcttga
     9781 taacatcaat atcatatgat tgattggagt agactgcaac agctccatag attacattaa
     9841 atggtttatc cgttatgttt aaaaatcttt ctactacatt ttcttgatca ctattagatt
     9901 tctttaacct taaatagcta gctacaattg aggttgaaaa tcgttcaaaa tctttatcag
     9961 aatgattaat agcttcttga agcttatttt tcgcttgaga gctactagaa tcagatgccg
    10021 atgattttac ttcaataact acaacctcat cattcgatac attcgaagaa tcttgcttat
    10081 atcctagaac atcacttcct tgagttgaag tatctttatt gactctacta tcataacgag
    10141 tcctaggaac cacatattct tcaatatttt gaagataatc agatactaat atttctccaa
    10201 aatcacctga catcgttgaa aggccaatac cactatccga gggtaattta aaatttttaa
    10261 gatactcttt aggggagata ttcataaaac ctatcatttc agcaagttca tcatcagaac
    10321 aataatttct tctgaattgg tttgcccaat cttcaaaaat ttctgggtca tcttgaatgt
    10381 ctaagtgaag aatctcaacc tgcttacctt catcagtaat aataggatct tcatgaatta
    10441 aatactttat ataactatgc atcttttcca ttacttttac tcatatccca caaccgttcc
    10501 tgccctatct tcaacatctc tttttcaacc gtgttccatt ctccaaatag taagtcatga
    10561 agaactgttg ctgctgaagt tgtattttct tttgaatcat atacacaact tctatctcgt
    10621 tgataaattt gaatgctttc aaagatagcc agttcttcca attgtcgtgt attatcaact
    10681 agatgattta caatgaaatc atgatgttct tttggagttg cgcgtgcttg atttggattg
    10741 atagcgtaca gttcttcgta tcggataaga gtgctcagat aggacagctc aggctttgtc
    10801 gcaatcaagg ctaattgtac ttcatatccc tta
//
LOCUS       DAVFJR010000057        10827 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVFJR010000057 DAVFJR010000000
VERSION     DAVFJR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.058"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(71..1282)
                     /locus_tag="VU722_001978"
     CDS             complement(71..1282)
                     /locus_tag="VU722_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HEU1772876.1"
                     /translation="MNNKTKKFTLATVLVLSLLGAGTLTSQSVVANDRLVSTQEINGQ
                     SYNILNSEVTSTSSGTTLVGIEGTFLTPDKQAILDRINAIRKEAADEGLVTSYVPIKW
                     STALEKTAFVRAAEASITIDHTRLSSKDIWTSWPAGNFSLSENLAWNYNGFMKAIQQW
                     YDEKADYVKSRSGVSVAGQTGHYKSLIDPKLTYMGLAAFENPVTQNGWITVAQSFGTA
                     SGGSEELAGSYGKAIQYTEANSSQIQTFATKANLFDKDLKAIRTHKTKNENTNSSQKN
                     EFNHSQYFGSWIQSNGRWWFKHNDGSYTSNGWEKINRTWYRFDNSGWMQTGWVKDGSW
                     YYLDGSGAMKTSWVKDNGSWYYLQDSGAMKTGWMKVSGKWYYAYSSGALAINTTTPDG
                     YRVNYNGEWVG"
     gene            1629..2581
                     /locus_tag="VU722_001979"
                     /pseudo
     CDS             1629..2581
                     /locus_tag="VU722_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2654..2938)
                     /locus_tag="VU722_001980"
     CDS             complement(2654..2938)
                     /locus_tag="VU722_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU1772877.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2992..3927)
                     /locus_tag="VU722_001981"
     CDS             complement(2992..3927)
                     /locus_tag="VU722_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU1772878.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4031..4474
                     /locus_tag="VU722_001982"
     CDS             4031..4474
                     /locus_tag="VU722_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU1772879.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLETDIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIECLEQFAEELAAKVG"
     gene            4590..4856
                     /locus_tag="VU722_001983"
     CDS             4590..4856
                     /locus_tag="VU722_001983"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU1772880.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4853..5227
                     /gene="crcB"
                     /locus_tag="VU722_001984"
     CDS             4853..5227
                     /gene="crcB"
                     /locus_tag="VU722_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU1772881.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            5221..5550
                     /gene="crcB"
                     /locus_tag="VU722_001985"
     CDS             5221..5550
                     /gene="crcB"
                     /locus_tag="VU722_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU1772882.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKMPLGTLIANLLGCLLI
                     GLFYNHVESKEVYAILATGFCGSLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVA
                     IFLGILL"
     gene            5669..6016
                     /gene="rplS"
                     /locus_tag="VU722_001986"
     CDS             5669..6016
                     /gene="rplS"
                     /locus_tag="VU722_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU1772883.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            6058..6129
                     /locus_tag="VU722_001987"
     tRNA            6058..6129
                     /locus_tag="VU722_001987"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6091..6093,aa:Arg,seq:cct)
     gene            6296..6463
                     /locus_tag="VU722_001988"
     CDS             6296..6463
                     /locus_tag="VU722_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772884.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(6695..7549)
                     /locus_tag="VU722_001989"
     CDS             complement(6695..7549)
                     /locus_tag="VU722_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1772885.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKYLLSVDTWMEYELKLFYNSVF
                     FMNTKTISLLYRIVIKKTRYFLKTNTGTHRIIPLYLFNLKLLLKNNLLDSAQFFIDDL
                     ENLLTRQGYYFEKNYLLFLKGIYLIKTNQIELGKKECSKAMRIFKEYNDSDTINELNQ
                     KFKLDLTI"
     gene            7643..8863
                     /locus_tag="VU722_001990"
     CDS             7643..8863
                     /locus_tag="VU722_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEU1772886.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFSNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEEASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            8876..9994
                     /locus_tag="VU722_001991"
     CDS             8876..9994
                     /locus_tag="VU722_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU1772887.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREEGTLNLIKPGRIVRQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYAFKSSGAMISADWLYDNGSWYYLKDSGSMVTG
                     WLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSMATGWVKDSGSWYYLKNSGSMA
                     TGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAWK"
     gene            10480..10749
                     /locus_tag="VU722_001992"
                     /pseudo
     CDS             10480..10749
                     /locus_tag="VU722_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
BASE COUNT         3443 a         1761 c         2145 g         3478 t
ORIGIN      
        1 atctctatac tatctgaaag tgaagattac tcactgtgag atagtataga gtctttttgt
       61 tgtagttaaa ttatcccacc cattccccat tgtaattgac acgataaccg tcaggtgtag
      121 ttgtattgat tgctagggca ccagagctat aggcatagta ccatttgcca gatactttca
      181 tccagcctgt tttcatagca cctgaatctt gaaggtagta ccagctacca ttatctttga
      241 cccaacttgt cttcatcgca cctgagccgt cgagatagta ccaactaccg tcttttaccc
      301 agcctgtttg catccaacca gagttgtcaa agcgatacca agttctattt attttttccc
      361 atccattact cgtgtatgag ccgtcattgt gtttaaacca ccaacgtccg tttgattgaa
      421 tccaacttcc gaagtattgg gaatgattga actcattttt ctgacttgaa tttgtatttt
      481 catttttagt tttatgagtt ctgatagcct ttaagtcttt gtcaaaaaga tttgccttag
      541 tcgcaaatgt ttgaatctga gaagaatttg cttctgtgta ttgaatggct tttccataac
      601 taccagctag ttcttcagag ccaccagatg ctgttccgaa actttgtgca acggtaatcc
      661 atccattttg agtgacaggg ttttcaaagg ctgcaagccc catataggtc agttttggat
      721 caattaagga tttatagtgt ccagtttgac ctgcaacact gacaccacta cgagatttaa
      781 cataatcggc tttttcatca taccattgct ggatggcctt cataaatcca ttgtagttcc
      841 aagccaaatt ttctgaaagg gagaaatttc ctgcaggcca ggaagtccaa atatccttgc
      901 tagacaagcg tgtgtgatca atggtgatcg aagcttctgc tgcacgaaca aaggcagttt
      961 tttctagtgc agttgaccat ttgatgggaa catagctagt aactagacct tcatctgccg
     1021 cctcttttcg aatggcattg atacggtcta agatagcctg tttatctggc gttaagaaag
     1081 ttccttcaat cccaactaga gtagtaccag aagaagtgct agtaacctca gagttcaaga
     1141 tattgtagga ttgaccattg atttcttgag tggaaaccag cctatcatta gcgactactg
     1201 attgtgatgt aagagttcca gctcctaaca aggaaagtac taaaactgta gcaagtgtga
     1261 actttttagt tttattgttc attttgtgtc ctcctatttt tattataaca tctttactgg
     1321 gtagagtaaa ctaaaattcg gtatagctag ggactatatt tattttaaat tgaaagttct
     1381 ataatgaagt tagccaccca ggcctcctaa aaattagatg ttttaactag cttatagcta
     1441 gtactcgatt tcatttgata agaggcttgg agctgttagg ctgacaagac aaggataaga
     1501 ttagccttgg tttagctgac aaaactgctt caagggttcc tcttgtcaaa tgaaagctct
     1561 tctaggcata agaaaacacc tctgtgttat acttgttgtt caaccacaaa cacaagaaag
     1621 gcacagagat gcaaaaccat tatactacaa aagccaaaca tttgacaatc gatagtcgtc
     1681 gcttaatcga acgatggaaa aaggaaggga aatcaaatag agaaatcgcc tctctgcttg
     1741 gaaaagctcc tcaaactatc catactgaaa tcaagcgtgg gacaatccga caatgtcttg
     1801 gaaaagggcg ctttaaagag gtttattctg ccgactatgc tcaacagtct tatgaaaata
     1861 atcgcaagcg ctcgatcaag aaatcaagat tgaacaagga gctgaaggaa aagattctcc
     1921 actatcataa ccaaaagttt tctcctgaaa tgatggtcaa ggctaagggc gttaacgtgg
     1981 gaatttttac catctactac tggatccatc atggaaaatt aggattgtca aaacaggatc
     2041 tgctctatcc tagaaaagga aaatctgtta agaaacaagc tagcaccaat tttaaccccc
     2101 ctggtcaatc caatctatcg aacagcgtcc tgaagctatc aatctgcgat tggagaatgg
     2161 gcattatgag attgatacgg ttctgcttac aagagtgaaa aattattgtt tactggtctt
     2221 aactgatcga aggactaggc atcaaattat ccgattgatt ccaaataaaa gtgctgaggc
     2281 ggtcaatcag gctttaaaac tcatcttaaa acaacaacaa attctttcca tcacggcaga
     2341 taatggtaca gaatttaacc gcttgtctga tgtattttct gaggaacata tctattatgc
     2401 gcacccctat gcctcttggg aaaggggaac taatgagaat cacaacaggc tcattcgtag
     2461 atggttacct aagggaacta agaaaacgac tcccaaagaa gtcgcattca tcgaaaattg
     2521 gattaataac tatcctaaaa aatgcttgaa ctacaaatca cccagagaag acttcttgat
     2581 ggctaacttg aacttgaaat ttggcgttga tttcaagaaa caaaaaagaa cagccgaaac
     2641 tgttctctta tcattatttg agaccgtatt ttttgttgaa acgatccacg cgtccatctg
     2701 cttgagtgaa cttttgacgt ccagtgtaga atgggtgtga gtctgatgaa atttccacac
     2761 ggatcaatgg gtaagtctcg ccttcgaact caactgtttc gttagagcgt tttgttgaac
     2821 cgctaaggaa ttggtaacca gtagttgtgt ccatgaagac aactgggcga tattctggat
     2881 ggatatcttt tttcattttg caatatttcc tttctgccat ggtctctttg cgagccatag
     2941 attgttacca tactagtcta tcagattctg aaaagtttgg caagtatttt atcagttttt
     3001 aagcaagttt tttaactttt ggtagatgat ttcgttttcc tctaggctat aggaattagc
     3061 accacttgct agagggtggc ctccaccatc atgttccttg gcaatttcat tgataggatg
     3121 gattttactg cgtaagcgaa cgcggtagtg gccatcagcc tgttccacaa aaattcccca
     3181 gagactaaca ctatcaatac gcccaggtgc acctacaatg gccgcagttt cagcatcggt
     3241 tacattgtat tgtttcaaga ttttctgact caggataacg cgagcagcac cattttcatc
     3301 cacttccaga tggtcgtaga tgtagccttg cagtttagca attttgtagc tcatagtgtc
     3361 cattttgcga gtgagagccg caaagtcaaa gttatgttct ctcaaataag cagccaggcg
     3421 aagagtccgt gcagtggtag aagggtagag gaagcgacct gtatcaccga caattcctgc
     3481 aaagagcaac tcagcatcgc gatctgccaa ggctagttgg gttgtttggg caaatagggt
     3541 aatcatctcg ctagcgctac ttgaactagt atcgacccaa gacaggtcac cgtatacatc
     3601 atcatttgga tggtggtcaa tcttaatgag aaaatcacct tgactatagc gcttatcatc
     3661 gatacgagca gtattagctg tatcacagac gatgacaagt gcgccttggt aggctctatc
     3721 ttcaacaaga tccatctcag ccatccaagt aagagttggt tcatcaaaac cgacggcttt
     3781 gatggttttt tctgggaaat gatgttccag caaggctttc aatcccacct gacttcccaa
     3841 ggcatcaggg tctggtttca tatgacgatg aatgataatg gtgtcgtatt ctttaatttt
     3901 ttctaaaatt tgttggcaaa tctccataaa taacctcaat tctttctcat ttcattgtag
     3961 cacaagaatt tttattttta aaatgaaaaa gatgtgatat aatggagaaa gataaattga
     4021 ggaggacgat atggcattag caaaaattgt atttgccagt atgaccggta ataccgaaga
     4081 aattgcagat attgtagcag acaaattacg tgacttgggc ttggatgttg atgttgatga
     4141 atgtacaact gttgacgctt cagacttctt ggaaacagac atcgctatcg ttgcgaccta
     4201 tacttatggt gatggtgaat tgccagatga gatgatggac ttctacgaag acctagcaga
     4261 tctcaacttg aatggcaaaa tctacggagt ggtcggctca ggagatacct tctacgatga
     4321 attctgtaag gctgttgatg actttgaccg tgtctttgtg tcaacaggag cagaaaaagg
     4381 ttcagagtgt gttaaagttg atctttctgc cgaggaagaa gatattgaat gcttggaaca
     4441 attcgcagaa gaattggctg ctaaagtagg ataagcataa aagtgcgctg atgtaatcaa
     4501 tcagtgcatt tttcttatcg agagttggga ttttactagc ctaatttatg gctttttgat
     4561 acaataattc aaataaagga ggagactgta tggatttaga tattattcgt caagaaatcg
     4621 atcaaatcga cgaccaaatt gtcaaactgt tagaagaacg aatgcattta gttgaggggg
     4681 tagttgctta taagaaagct tcgggtaaac cgattttaga tactaagaga gaagaagtta
     4741 tttttgaaaa ggttaggagt cgtgtagagg acaagcgcta tcaggagact attgtagcga
     4801 ctttttcgga catactcaaa cgttcgcgtg attatcagga tcagaatatc aaatgaaaaa
     4861 agaacaattt tatccgctag gaatttttct agctgctatg ttgggcggac ttgtccgata
     4921 tctagtttcc acctggttac cagccagtcc agactttcct tggggcactc tctttgtcaa
     4981 ctatctggga attttctgct tgatttatct tgtcaagggc tatctggtct ataaggggac
     5041 tagtaagggc ttgattttag cactggggac gggtttttgc ggaggtttaa caactttttc
     5101 cagcctaatg cttgatactg tgaagctgct tgatacaggg cgttatctta gtttagtcct
     5161 gtatttgctt ttgagcatcg gtggaggcct actcttagct tattttctag ggaggaagaa
     5221 atggtaatcg tctatcttgc aattgcttgt ggtttcggag ctttagtacg ctatttattt
     5281 tcccgctaca atcaagcttc taaaatgccc ttgggaacgc tcatagccaa tcttctaggt
     5341 tgtttgttga ttggattatt ctacaatcat gtagagtcta aggaggtcta tgctattcta
     5401 gcaacaggat tttgtggaag tttgacaact ttttcgactt tgaatgacga actccaaagg
     5461 ttgctaagcg ataagaaggt attttattct tacctgattt tgacctacct aggtggtttg
     5521 gttgcgattt ttttaggaat tctgctataa atttctttac ttttttttag aaatttggta
     5581 aactgtatct tgtgtgtaat ggacgcacaa aaatacagtt tatccgctga ggaagattcc
     5641 tcaagattga caaagatagg agaataaaat gaatccatta atccaaagct tgactgaagg
     5701 tcaacttcgt acagatatcc catcattccg tcctggtgac actgttcgtg tacacgcgaa
     5761 agttgtcgaa ggtaaccgtg aacgtatcca gatttttgaa ggtgttgtta tcgcacgtaa
     5821 aggtgctgga atctcagaaa actacacagt tcgtaaaatc tctaacggtg taggtgttga
     5881 gcgtatcttc ccaatccaca ctccacgtgt tgaaaaaatc gaagttgttc gttacggtaa
     5941 agtacgtcgt gcgaaattgt actacttgcg tgctcttcaa ggtaaagcag ctcgtatcaa
     6001 agaaatccgt cgttaattcg actaaaaaac tctgcttttc agcagagttt ttatctagct
     6061 cccttagttc aatggatata acaactccct cctaaggagt agttgcaggt tcgattcctg
     6121 cagggggcat ttttagtaat gtaaagaaag acaaagaaaa ttcaaaatgt ttatttgaag
     6181 gcaattttct caagttcatt tttaaaaata atttagcatt tttaattttt ttgaccaaat
     6241 tttgaccaaa aattatattt tggtcaatga ttatagaata aaatggatca tgaaaatgtc
     6301 tctgatttat agtagtgcta aaaaggactt cctttattgg aatgtcctta tttttattat
     6361 ggaattgcca aatgacgtta aggttcagtt ctatgaactt agaaagaaag tacaaagctt
     6421 taatcagctt tcaaaaagat ttggtatgga tgtttctggc taaggtatgt gacaaggtga
     6481 attgatcgtt attgaacaga gagcgttaaa aaagggaaga atcgttacta ttccactgaa
     6541 ttaaaacaag aaataaatca acaaaagcct atataataac aaatgtatta aaaataaaaa
     6601 gatttagttc agtgtaatgc agaaccaaat cttatggata aattatttgt ctaatttttt
     6661 aggaattata tctctaaaca atatcattta acaattaaat tgttagatct agcttaaatt
     6721 tctggtttaa ttcatttatt gtgtcactat cattatattc cttaaatatt ctcatagctt
     6781 tagaacattc ttttttacct aactctattt gattagtttt tataagataa atacctttta
     6841 ggaagagtaa ataattcttt tcaaaataat atccttgcct agtaagcaaa ttttctaaat
     6901 catctataaa aaattgagca ctatctaata aattattttt taataataat tttaggttaa
     6961 ataaatacag gggaattatt ctatgcgttc cagtattagt ttttaaaaaa tatcgtgttt
     7021 ttttgattac tattctatat agtaagctaa tggttttagt attcataaaa aacactgaat
     7081 tatagaaaag ttttagttca tactccatcc aagtatctac agaaagcaga tattttatta
     7141 attcattaca tttagatgaa ttataaggaa ggtttgcaag acgattaatc tgttgttcag
     7201 caatcaattt tatgtgataa ttgcataaac ttttttcttg cttttgtttt aactctattt
     7261 tatccactaa ttcttgaagt aaaaatatat ctgaagaatt tacagcatgt tctaattctt
     7321 caaaaagaca ttcttttttg gaataataac aatgaactaa ttcttcaaat tctgaaaatg
     7381 atattccaag acggtttaac agaatataaa aatgattaat agataatttt gtaatgccat
     7441 tttcgaaacg agaaatagtt gattcactaa tttcattaca tgataaatct ttaaggcgaa
     7501 aattttttga aatacgaata tcctttaaaa ctgctccgaa attttccata atgttcctct
     7561 tccatttctg caaaaaataa aacgcttgtt ttttatttat gatatgatta tacaaaaata
     7621 aaatagaaag gacaataata tcatgaaaaa aattttattg tcaacagttg ctttattaag
     7681 cttagtagca tctctgctag caaataatcc agtttctgct caagaatcat cctctcaagc
     7741 aacttatagt aagtcaagtg gaagttggat aaaatctggt aaccgttggt ggtataagca
     7801 ttctgatggt tcttatacta caaatggatg ggaaaaaata aatggtacct ggtactattt
     7861 tgatagtgaa ggttggatga agacaggttg gattaaagaa tatgggaaat ggtattacct
     7921 agatgatagt ggtgctatga aaactggatg gtgtttggtt tctggtagct ggtattattt
     7981 aaatagtagc ggtgtaatgc aaacgggact acagactatc aatggaaaac aatattattt
     8041 agctgccggc ggtgctatgc agacaggttg gcacaatatc ggagatgata cctatttctt
     8101 tgctaatagt ggggaaaatc aaaatatcaa tcgtcgtgct ttagttcttg gtgaaacatc
     8161 aacgagagca gtacctattg cagatgttaa tgctatggaa aaggttttta gtaaccaaaa
     8221 ctttagtgaa gttgttcgtt tcccagatag aacaaaatcc gagataattg caaaaatgca
     8281 agagcttttt gaatcttcta gcgaaggcga tgtgaactat ctttacttta cttgtcatgg
     8341 aggaagagat ggaagaatct atattggtag tgatggccta gcattttctg gttgggaatt
     8401 ggcgtccgtt ttgaaacaat acaaaggtaa gtttgttgtt atgctggatt gttgtcatgc
     8461 tggaacaatt atttctaaag ataatacagg tgaaggcaat gaagaagcct ctacggaata
     8521 ttttgattta gatgaatttg tatcaggatt ttctaatatg gatggtaacg aaaaatcagg
     8581 tgagatgatt gactctaaat ttttagtatt atgctcatca agaggtgcag aatactctag
     8641 tggtggatca ttaagtttag cgactaaata ttggtcttta ggttcaggat ggaatcctct
     8701 acagaattca caagcatatt tagcagcaga ccaaaataat aatcgcagaa tcacattaaa
     8761 tgaattgtat acatactctc gtgaacaagt tttgaaacaa aattctaacc agcatattga
     8821 agtttatcct gacaacagtc aatttgtgtt atttaagaaa taagggggca ataaaatgaa
     8881 agtatcaaaa aaaattacac tatttagttt gtcttttgca ggttttgttt tattgacttt
     8941 acctcaagca ggaaaggctt ttgaacttaa agaagactgg gcatttaaag gtggcattcg
     9001 atacgagaat gggaaagtca gcaaaattaa taatggatat gaagtaaata ttaaagtgtt
     9061 agatttacct agtactagcg caatcgaatg gacagttaga ttgaatggag aaaagcaaaa
     9121 tactaacttc ttagcggagg aaagaactgt atctaaaact gaagataagg gacgtttctt
     9181 gcacttttat atcccctatg gatatcgtgg ggatattgta gtagaggcta agagtggaaa
     9241 cgaagtgaag acttggtcta ctaaggtagt tgacgatgtt tattcagatt ctgctaagag
     9301 tggctacttt attctcgatg gggaacaaat cttagaaagt tcatgggatt ccgtaaatga
     9361 gtcttatatt gcaacgcttc caactgtaac atcaggaaaa actgttgttg cttggcgtga
     9421 agaaggaact cttaatttaa ttaaaccagg aagaattgtt cggcaatata atagcagtgg
     9481 atcatatgta gaactttctc caatctttga aactgctagt tggctaaaat caaaccaaaa
     9541 ctggtactat caaaaacaag gtcaattagt tcaaaattct tggatcaagg atcagggaag
     9601 ctggtatgcc tttaagtcat caggagccat gatttcagct gattggttgt atgataatgg
     9661 ttcttggtat tacctaaagg actcaggttc tatggtaaca ggatggctta aaaatggagg
     9721 ctcttggtat tacctaaaca agtcaggttc aatggctaca ggttggatta aagatagtgg
     9781 aacttggtat tatctaaaga attcaggctc tatggcgaca ggctgggtga aagatagtgg
     9841 ctcttggtat tatctaaaga actcaggttc aatggcaaca ggttgggtca aagataatgg
     9901 taagtggtac tatctcgcat catctggtaa tatgcttcgc aatacacgca caccagatgg
     9961 ctattatgta gatggcagtg gcgcttggaa ataaattttt aaaagagaaa atctactgag
    10021 aaggtagatt ttctttttag ttaatgaata tagaataaag tagatcagga ctggtctatt
    10081 ttattttgta actattaatg aatagtctta atgatgaagt tattttctga agatatttaa
    10141 ttgtgttgag atttgataaa actatagtgg attgaaataa gatataaaca aagagattat
    10201 ggaagtcaaa ttaatttcta aaaacgtttt aaaatcctta gcgtactatt ttagattcaa
    10261 tttaatatag tttaaaaata agaaaattac gtaccttatt cttggtgata aaaatgcgaa
    10321 tttagataaa tatatttgat ttgtagaagg tgctcataat ccatatttta aaatttatac
    10381 tattatactg aaatttaatt gtagtttatt gaatgctatg tatttttatt tcttaatgct
    10441 ataatataaa gtatatagag ttattttaga ggtgcagatt tggccaataa taggaaaact
    10501 gagacattag gtgtttcata tctttcaaca tttatagata agcatgagtt acttcaatct
    10561 tattttgaaa gtaatgataa aactccagta tgggatgggg aaattcatgt tcttaaatca
    10621 actagtgaga agaaggaaga aatattcggt aaagtgcctg ttcaaataaa agccactaga
    10681 caaaaaatga atgcacttaa atcattttca ttaaatatta gtgatttaga attatataaa
    10741 tcaaatggtg tactgacccc aaaaagttag acaaataatt tattcaaagg atttagttct
    10801 gtactgcaca ggactaagtc cttttag
//
LOCUS       DAVFJR010000058         9630 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVFJR010000058 DAVFJR010000000
VERSION     DAVFJR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.059"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..288
                     /gene="pmp23"
                     /locus_tag="VU722_001993"
     CDS             <1..288
                     /gene="pmp23"
                     /locus_tag="VU722_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU1772888.1"
                     /translation="DIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLG
                     NTTGKTYSYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSISG"
     gene            362..1336
                     /locus_tag="VU722_001994"
     CDS             362..1336
                     /locus_tag="VU722_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU1772889.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVTFFKSFGS"
     gene            1410..2768
                     /gene="rlmD"
                     /locus_tag="VU722_001995"
     CDS             1410..2768
                     /gene="rlmD"
                     /locus_tag="VU722_001995"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU1772890.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTDSFI
                     KASAQTGVDRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECVSLLEK
                     RN"
     gene            3036..3602
                     /locus_tag="VU722_001996"
     CDS             3036..3602
                     /locus_tag="VU722_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772891.1"
                     /translation="MVILELYQNDYSKDLVAFNSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESCGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            3903..4661
                     /locus_tag="VU722_001997"
     CDS             3903..4661
                     /locus_tag="VU722_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU1772892.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMEIRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYELDIGVTRDGRTLVVEVNDGYALGNCGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            4719..5573
                     /locus_tag="VU722_001998"
     CDS             4719..5573
                     /locus_tag="VU722_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU1772893.1"
                     /translation="MLGAITGDIVVSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            5735..6568
                     /locus_tag="VU722_001999"
     CDS             5735..6568
                     /locus_tag="VU722_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU1772894.1"
                     /translation="MDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAV
                     VVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLT
                     NKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNI
                     KVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDL
                     LKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKE
                     D"
     gene            6731..8419
                     /locus_tag="VU722_002000"
     CDS             6731..8419
                     /locus_tag="VU722_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU1772895.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQLFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DHHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPALYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNC"
     gene            8745..9200
                     /locus_tag="VU722_002001"
     CDS             8745..9200
                     /locus_tag="VU722_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772896.1"
                     /translation="MGAARDFLELINYKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         3200 a         1555 c         2021 g         2854 t
ORIGIN      
        1 gatatctgga cagctgttca agcctataat tttggacctg cctatatcga ttttatcgcc
       61 caaaatggca aggaaaatac cttggctcta gccaaacagt actctcgtga gactgttgcc
      121 cccttgcttg gtaatacgac tggaaagact tatagttata ttcaccccat ttccattttt
      181 cacggtgctg aactctatgt aaatggagga aactattatt attctagaca ggtacgactt
      241 aacctttaca tcatcaaatg tttcactctc ttttcaatat ctggctagac caggtgtttt
      301 tgttataagt tttctttaag atagatatat tactctaaag aagtaaagga ggaaattccc
      361 tatgagaaag aaactctttc tgactagcgc tgcgatcttg tgggcagtaa cagctatgaa
      421 tagcgtccat gcagcaacag atgttcaaaa agttatcgat gaaacctatg tccaacctga
      481 atatgtccta ggttcttccc tatctgaaga ccaaaaaaat caaactctta aaaaactggg
      541 gtacaatgcc tcaacagata ccaaagaact caagaccatg acacctgatg tttattctaa
      601 aatcatgaat gtggccaatg actctagctt acagttgtat tcatcagcca agattcaaaa
      661 gctaggtgac aaatcgccac ttgaggtcaa gattgaaaca ccagaaaata tcactaaggt
      721 gactcaggat atgtaccgaa acgcagcagt aacgctgggt atggaacatg ccaaaatcac
      781 tgtagcagcc cctattccag ttacaggaga aagtgcttta gcagggattt actattcgct
      841 agaggctaat ggagccaagg tgccacaagc taataaagat ttggctcaag aagagttgaa
      901 ggctttgtca gatatcaatg ctgaaaacaa ggacaaatca ggctatgatg ctaataaatt
      961 aaacgttgcc ctagctgata tcaagtcagg actcgccaaa gctaaagaaa gcaagggaaa
     1021 tctgacagaa gaagatatcc gcaagattgt tgaagatacc ttaaaaaatt acaaacttga
     1081 tcaggtcata acaggaaacc agatcaatat catcatcaat tttgccttga atctctcaaa
     1141 gagtgatatc ctcagcaatg cagatttcac taaaacccta aatgacctta aacaaagcat
     1201 cgtatcacaa gctggcgaca gttttaaaaa tatcaacctt aactttgatg cggataaggc
     1261 gctagaggac ggtggtaact tcttaagctc cctctggcaa gcccttgtca ccttcttcaa
     1321 gagttttggt tcttaagaaa tttcatggta taatggatgg taaccgtaac gttgccgtct
     1381 tttttgtcgg ccaatagaaa gagaaaagaa tgttaaagaa aaatgatatt gtagaagttg
     1441 aaattgttga cttgacccat gaaggggcag gagttgccaa ggtagatggt ttggtctttt
     1501 ttgtagagaa tgctttaccg agtgaaaaaa ttctcatgcg tgtcctcaag gtcaataaaa
     1561 agattggctt tggaaaagtt gaaaaatacc ttgtccagtc accacaccgt aatcaagatc
     1621 tagatttggc ttacctgcgt tcaggaatcg cggatttagg acacctttct tatccagaac
     1681 agctcaagtt taaaaccaag caagtcaagg acagtctcta caagattgct ggaattgcag
     1741 atgtagaagt tgctgaaacg cttggtatgg aacatccagt caagtatcgc aataaggcgc
     1801 aggtgcccgt tcgtcgagtg aatggtgtct tggaaacagg atttttccgt aagaattcgc
     1861 acaacctcat gccccttgaa gatttcttta tccaggatcc tgtcattgac caagtcgtag
     1921 tagctcttcg agacctgctc cgtcgttttg atttaaaacc ttatgacgaa aaggaacagt
     1981 ctggattgat tcggaatctt gtggtgcgtc gtggtcacta ttcaggacaa atcatggtcg
     2041 ttttggtgac aactcgtcca aaagtttttc gtgttgacca attgattgaa caagttatca
     2101 agcagttccc agagattgtg tctgtcatgc aaaatatcaa cgaccagaat accaatgcga
     2161 tttttggtaa ggagtggcgc actctttatg gtcaagacta tattacggac cagatgttgg
     2221 gaaatgactt ccaaatcgct ggcccagcct tttaccaagt caatactgaa atggcggaga
     2281 aactctatca aacagccatt gactttgcag agttaaaaaa agatgacgtg gttattgatg
     2341 cttattctgg tattggaacc attggtttat cagtcgccaa gcatgttaaa gaagtctacg
     2401 gtgttgaact gattccagaa gcggttgaga atagtaaaaa aaatgctcag ctgaacaata
     2461 tttcaaacgc ccactatgtc tgtgacacgg ctgaaaatgc catgaagaaa tggctcaagg
     2521 aaggtattca accaaccgtt atcttggtcg acccaccacg aaagggattg accgatagct
     2581 ttatcaaagc aagcgctcaa acaggagtag accgcatcgc ctatatttcc tgcaatgtcg
     2641 caaccatggc gcgtgatatt aaactctacc aagaattggg atatgaattg aagaaagtcc
     2701 agccggtgga tctatttcct caaacgcatc acgtcgaatg tgtgagtttg ttagagaaac
     2761 gcaattaatc ctcaaaaggt tccctgaacc ttttgagtcc cactgaggca tcacgctgag
     2821 gcggtatcac tgcttgtacg agttgaagca tcagcgaagt aaaagtagat gttcagccaa
     2881 tgcgacgagg tgagaccgaa ggtcgataag gtgtgttctg ggtataggac tcgtaaagta
     2941 agtaggaaat atgatgagat gatacagaga gcctgaattg gtcaggtgac gtgcttattt
     3001 acattagcct gataatgaaa atggagagat tatcgatggt tatattggaa ttgtaccaaa
     3061 atgattattc taaagattta gtagcattta attccataga agatgggaaa gcctttgtag
     3121 ctcaaatccc gggatacact ctggaaacag aagatggttt tgaagtggag tattttaatc
     3181 ctaaaaacat accggattat atggaaatta tttttaacgg aaatattgtt cctttatcta
     3241 aatttatgtt cgatcctgag gaaaatgtaa acattatttg gaaagagatt tcaaatttat
     3301 ccctcaaaaa tgatagagtg atcgaaggat attcaaaaat tgatgcatat gtcgttaaca
     3361 accatgaagt taaagcctat gtcgaaacaa gagaaacgaa ctatcgtaaa gcaaaagact
     3421 tcttagaaag ctgcggatat gaaatcgaca gaagcttttt cggaagtgaa gacggtgaag
     3481 cgattcttta cagaaaaaaa gggatcgaag tttggcattt cttgtgtcac ttagacccaa
     3541 tgtttgtaga gattgaagat gtagaaggat atgttaaaga agaagttgga gagattcaat
     3601 agtcaaccaa agttccttgt gaatatatac ctttgctagt aaaagagtca aaacgttata
     3661 acgaaggggg taagaaaacc cttgagtgta agtctttttc ttgtttagag ggaaagtatt
     3721 agagtggccg ctcataattt atactagatt tgataactga tttgagacag attttatttc
     3781 tataaatatt gtgaaaattt tttaatacca aagatttaaa gttactgtgt taaaaatcct
     3841 ctccactttt aaactaatgt attataaaag ccagttgaca ctagtgatat aggagtgatg
     3901 aaatggttgt ttatattaga caaagtaaat taccaagtga ggtttcaatt aataaataca
     3961 atgctcaagt aggtgcctac ttacaaggag aagaagttat tttatatcaa tctttttctg
     4021 aaataaaaga gttaacaagt gaagatatag ttgtagatta tataatggag attagagcat
     4081 tactaaaaat gatgggctta aacgttccgg tttatgatta tcctattgag cttaaagagt
     4141 tttatggtcg aaagatttat gctggtattt taggagagat tgtgaatata cctgataatt
     4201 ggggaaaatt tattaagcct aaagctggtt caaaagtctt tactggaaga gttgttaatg
     4261 gaacccatga tttaataggt attggtctac ctttcgacta tcctatatgg attagtgagg
     4321 ttgtagaatt catagctgaa tggcgttgtt ttgtgttaga tggtcgcgta ttagatgttc
     4381 gaccctatac aggtgattat catgcacaat ttgatgcaag tgtaattgat gaagcgatat
     4441 catgttggaa agatgcgcca atagcttatg aactagatat cggtgttact cgcgatggca
     4501 gaacacttgt tgttgaagta aatgatggtt atgcattggg aaattgtggc ctatctcctt
     4561 taaaatcaat caattttcat agagctaggt ggaaagaaat ggtaaaaccc tattttgaaa
     4621 aaaatgaaat ttttaaaatc caacaggatg ttattttcta aaataaatat ggtagataac
     4681 caatataaaa agcatcaaaa tgaacaagga ggaatctgat gcttggagca attactggag
     4741 atattgtcgt ttctgtttac gaatggaaca atatcaaaac aaaggacttt cctttatttc
     4801 ggaaggactg cttttttaca gatgacacgg ttatgacctg tgctgttgca gaagcaatta
     4861 tgaatggtgg acaaaaagac gacttcattg acgcgatgaa gaaatatggc agaatgtatc
     4921 cgaatgctga ttacggtgct cggtttaatg catggctaaa cagcgataac cgtgagcctt
     4981 ataatagctt tgggaatgga tcagctatgc gtatttctcc atgtgcttgg atcatggact
     5041 gtggttttta tgcgaaaact ggtatatggc catcatctag aggacttacg agtctttctg
     5101 cagaggtaac tcataatcat ccagaaggtg tcaaaggcgc tatggctaca gctgatgcta
     5161 tctttctatg tcgtttttac tttggtggtt attgtagaga gtacgagcaa tcaattaacg
     5221 acaatcctac agagtgtaaa agacgaatta aggattatat agaaaaagaa tacgattaca
     5281 atctatctca aactttagat gaaatccgtc ctaactatcg ttttaacgaa acatgtcagg
     5341 aaactgtccc tcaagccatt atcgcctttc ttgaaagtag agacttcgaa gatgcgataa
     5401 gaaatgccat ctcacttggt ggcgacagtg atactctcgc agcaatcact tgtagcatag
     5461 cagaggcagc ttacggtatt cctgattgga tcaaggataa ggcctattct tacttggatg
     5521 aacccttaaa ggatgtagtt aggcgatggg aaaatagaat aaaagcgtat taatctccag
     5581 tacgtcagat ttctcttttc tgtattttca ttgtataata ggattacatt tacttgcata
     5641 cgacgaaatg taaacatttc tgtttaaaat taaggataaa atcaatgaaa aaagcaatgg
     5701 taattatcaa ccctacttct gtggcgagaa ggctttggat tacaaagaaa agctggagaa
     5761 taaagcaaaa gaatactttg aatatgttga aaccaaaatt accgaaaaag cgctggatgc
     5821 aacacatttt gctgaagaag cttctcgtga gcagtatgat gcagtggttg tgtttggtgg
     5881 agatggaact gtcaatgaag tcatttcagg tattgatgag agagactaca ttcctaagtt
     5941 agggattatc ccaggcggta cgggtaacct cattacaaaa cttttggaaa tcaatcaaga
     6001 catcgatggc gcaattgacg aactggattt tgatttaacc aataagattg atatcggtaa
     6061 agcaaatgac aactattttg gttatatctt tagtatcggt tctctgcctg aggcgattca
     6121 caatgttgaa atagaggaca aaacaaaatt cggtatttta acctatgctg taaataccat
     6181 gaagtctgtc atgacagatc aggtctttaa cattaaggtt gagacagaaa atggaaatta
     6241 tgttggtgaa gctagccatg ttttggtcct tttgacaaat tacttcgctg ataagaaaat
     6301 ctttgaagaa aacaaggacg gctatgccaa cattttgatt ctgaaagatg cctctatatt
     6361 ctccaaatta tccgtcattc ctgatttatt aaaaggggat gttgtcgcaa atgataatat
     6421 cgagtatatc aaagcgcgta atattaaaat ctcttcagat agtgaattgg agtcagatgt
     6481 tgacggagat aaatcagata acctacctgt agaaatcaaa gtcctagctc agcgagtaga
     6541 agtattttca aaaccgaaag aggattagta tatagagaaa gcctttttta aggctttttg
     6601 tatactttaa aagatagttc ctttaacaac ggacattcct tgcaaatagt ttacaaaaat
     6661 agtatactgg attcattaag tttgaaaacg tttgcgtaaa atttgaatga atactttagg
     6721 agacaaattg atggaattga gtgctattta ccataggcct gagtcggagt atgcctatct
     6781 ttataaggat aagaaactcc atattcgaat tcgaactaag aaaggggaca ttgaaagcat
     6841 caacttgcac tatggggacc cttttatctt tatggaggag ttttatcagg atacaaaaga
     6901 aatggtcaag ataacttctg gtaccttatt tgaccattgg caggttgaag tgtcagttga
     6961 ctttgcacgt atccagtatc tctttgagct cagagataca gaaggtcaaa atattttgta
     7021 tggcgataaa gggtgtgtgg aaaattctct agaaaatctt catgcaattg ggaatggatt
     7081 taagttgcct tatcttcatg agattgatgc ctgcaaggtt cctgactggg tttcaaatac
     7141 ggtatggtat cagctatttc ctgaaagatt tgccaatggc aatgctctat taaacccaga
     7201 agggacttta gactgggatt catctgtcac acctaagagc gatgatttct ttggtggtga
     7261 tttacagggg attattgatc atatggatta cttgcaagac ttgggtatta ctggactata
     7321 tctttgtccc atctttgaat ctacaagcaa tcacaagtac aatacgacag attactttga
     7381 aattgaccat cattttggag acaaggagac ctttcgggaa ctggtggatc aagcgcatca
     7441 tcgtggcatg aaagtcatgc tggatgcggt atttaatcat attggttcgc aatctcttca
     7501 atggaaaaat gtcgtcaaaa atggtgaaca gtctgcttat aaggattggt tccatattca
     7561 acaattccca gtgacaactg aaaagctagt taataagaga gacttaccct atcatgtttt
     7621 tggtttcgag gactatatgc ctaagctaaa tacagccaat ccagaggtca agaattatct
     7681 tttaaaggtt gcgacttatt ggattgaaga gtttaatatc gatgcttggc gtttggatgt
     7741 ggctaatgag attgaccatc agttctggaa ggattttcgt aaggcagttt tagctaaaaa
     7801 tcctgctctt tatatcctag gagaagtctg gcatacatct cagccttggc taaatggaga
     7861 tgagttccat gccgtcatga attatccttt atctgatagt atcaaggact atttcttacg
     7921 aggaattaag aagacagacc agttcatcga tgaaatcaat ggagagtcta tgtattacaa
     7981 gcagcagatt tcagaggtca tgtttaatct cttggattca catgatacag agcgaatcct
     8041 gtggacggcc aatgaagatg ttcaactggt taaatcagcc ttagcctttc tctttttaca
     8101 aaaaggaaca ccgtgcattt attacggaac cgagctagcc ttgactggag gaccagatcc
     8161 agattgccgt cgttgtatgc cttgggaacg tgtatcaagt gacaatgata tgctgaactt
     8221 tatgaagagg ctaattaaga ttcggaaata cgcgtcagta atcatttcgc atggcaagta
     8281 tagccttcaa gaaatcaaat ctgatctagt agctctggaa tggaaatacg aaggacggat
     8341 cctcaaagca atattcaacc aatcaacaga agattatctt ttagagaaag aagcagtagc
     8401 actagcaagc aattgctaag aattggagaa tcagcttgtc atctctccag atggatttgt
     8461 gattttctaa aaactagttg atgaagatta tggtacattt catatcttat atagtataat
     8521 aaggctagtt actaaacttg taaaggagaa cttaaatgaa ttgtagagga catgaaacaa
     8581 gacaaagaat tgttagagat tttgaagttt agcctaaagc acatattaag ctgttagcaa
     8641 atcaacaaaa acatagtgat gcaggagcaa ctattgaaga tgaatattat gtatttatcg
     8701 ctgagagtaa aattgatggc aagaaggaag ttattcagtg ttgcatgggt gcggcaaggg
     8761 attttttaga actaattaat tacaaagggc tacctctttt taatccgctt gtaggtgatt
     8821 ctcatgtaaa taatagacaa gaatatgaca atacagggag tggaaattta caacctgaaa
     8881 agtggaatga aactgcaaag cagctttata atgctataat gtggttgatt attttatgga
     8941 atgctaagcc ggatacacct ttatttaatt ttaaagacga agtaattaag tataaaacat
     9001 atgagccttt tgaaagcagt ataaaaagag taaatactac tataaagaat ggtagtaaag
     9061 ggaaaactct gactgagatg attaatggct acagagcgga taacgatatt agagatgaaa
     9121 tttgtaactt taatattctg aaaaataaaa ttcgtgatat gaaagaccaa caaggaaata
     9181 caatggaatc ttacttttag ttattgttga attttgggta ttctataaaa tatcctaatt
     9241 gagatttaaa tagtagacta tacaatatag ttaaaatatc agtaaaaaca acactttatt
     9301 gaggtattgg atacgctttg ctaatagcct aataatcaca tgtggagtgt tgctacaacg
     9361 aaaaaggtga taatccttga tttcaagcta ttttataagc attttgtctt tgtagataaa
     9421 gacaattttg acaataaaaa tcctaaaagg tgaatcgtta tagatgtatt tgtagatatc
     9481 gtttgcgcat cgaaaaaatt aatacaagaa taaatattta tggctcttta ggtgactttt
     9541 atagaagtaa agtttaggat agacaaacaa gaaataacgc accatttttg gtgcgttatg
     9601 cttttttatg ctataatgga tttataaaaa
//
LOCUS       DAVFJR010000059         9276 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVFJR010000059 DAVFJR010000000
VERSION     DAVFJR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.060"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(166..783)
                     /locus_tag="VU722_002002"
     CDS             complement(166..783)
                     /locus_tag="VU722_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU1772897.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLPIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(773..1546)
                     /locus_tag="VU722_002003"
     CDS             complement(773..1546)
                     /locus_tag="VU722_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU1772898.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVNVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVADLPIAPTHVVSSLAEWDFDEN"
     gene            complement(1557..2294)
                     /locus_tag="VU722_002004"
     CDS             complement(1557..2294)
                     /locus_tag="VU722_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU1772899.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSNFDKKLIRGPKYESLEELISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(2299..3429)
                     /locus_tag="VU722_002005"
     CDS             complement(2299..3429)
                     /locus_tag="VU722_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU1772900.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(3513..3902)
                     /locus_tag="VU722_002006"
     CDS             complement(3513..3902)
                     /locus_tag="VU722_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU1772901.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(3918..4301)
                     /locus_tag="VU722_002007"
     CDS             complement(3918..4301)
                     /locus_tag="VU722_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU1772902.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(4302..5090)
                     /locus_tag="VU722_002008"
     CDS             complement(4302..5090)
                     /locus_tag="VU722_002008"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU1772903.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(5083..6018)
                     /locus_tag="VU722_002009"
     CDS             complement(5083..6018)
                     /locus_tag="VU722_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU1772904.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIVILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(6148..6324)
                     /locus_tag="VU722_002010"
     CDS             complement(6148..6324)
                     /locus_tag="VU722_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU1772905.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(6464..7171)
                     /locus_tag="VU722_002011"
     CDS             complement(6464..7171)
                     /locus_tag="VU722_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU1772906.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            7322..8350
                     /gene="queA"
                     /locus_tag="VU722_002012"
     CDS             7322..8350
                     /gene="queA"
                     /locus_tag="VU722_002012"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU1772907.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVSTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVNN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPRYGWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            9041..>9276
                     /locus_tag="VU722_002013"
     CDS             9041..>9276
                     /locus_tag="VU722_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772908.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYNFQKPSKIPYLETTGMPTRILLRKRR"
BASE COUNT         2803 a         2106 c         1701 g         2666 t
ORIGIN      
        1 aaaataaggc gcttgactag ggatttttag aaaaaaagcc tattttttca agaaaaatag
       61 gctgtttgcg aacgattgac acaattggat ttggttaatt cactcttaac gatggtttta
      121 aacgatatat atatttatat atgcaaatta aaaacatctt tcatttcact tcctacgact
      181 tttcagacac agatagccaa agaagctttc atagagggca aaaaagagga ggaaggcatg
      241 aagaaagaag gtctctggca aaatcataat aacaggatcc ttggctggat caaaaagcca
      301 ggtatcatct cccacaaaga gaatttgatg gaaaagagta aagaattggt caaaaccaat
      361 caaaactccc ccaagtccaa tcatcacagg taagactact agagccagga gactttttcg
      421 ataaagagac aaaaagtcct ttttcacaat tctattgaca aagacataga aacttggcag
      481 tgtcactaga gctactagct gaaccaaatg aaagagattc ttgaccactg cgaaatggtg
      541 cagaccagct gctgacgaac gaaaatcagg catctgtaag acctgactaa aaggattggt
      601 cagataattc atcaagatat gaaaattgta ttgaatggtt tctggtttta gatagactcg
      661 attcgttaag tttagccact gaatctccat aggatagaaa atccaagcca gataaatggg
      721 cagaaggatt gagagggaga ggagaaagag catagagccc caaaaggtca atttagtttt
      781 catcaaaatc ccactccgca aggctagaaa ccacatgtgt cggtgcgatt ggcaggtcag
      841 ctacttcttc tgccttagta aaacctgtcg tcaccaagag cgttggaatg ccattgtcaa
      901 tcccagcccg gatatcagtc aaataattgt ccccaaccat aattaactct tcacgttcca
      961 aacctaagtg ctcaaccgcc ttgtccataa tgatggcatt tggttttccg atataaaccg
     1021 gcttcactcg tgtcgctact tcaagcagcg taatcagtga gccagcacct ggcaaaagac
     1081 cgcgttccgt cgggatgttg aggtcaggat tggttccgat aaaatgggca cccttttgaa
     1141 tagcaagagt tgctgtggca aatttttcat agtcgacttg ccaatccaga ccaactacca
     1201 cgtaggcagg tttttccttg tcttccacat aaccagccgc cttgatggct tccttgagtc
     1261 ctgcttctcc gacaacattg acggtctttt caagccccaa atcattcata tagtcgatgg
     1321 ttgccaaagt cgctgtgtag acagtcgata ggggcgtatc gatattaaaa ttctgagcca
     1381 acatctcctt aacactctct ggagtgcgag ttgtattgtt ggttacaaag agatagggaa
     1441 tgtcccgctt ttgcaattca tgaacaaaag tctctccagc agggattcgg tctttcccct
     1501 tataaatggt tccgtctaaa tcaattaaat agcctttata tttcatctat ttctccctaa
     1561 gcctttttta tttcttgcca agtaatgatt gcttgggcat tgataacccc atcacttgta
     1621 atttcatgct tgctttccag tccagtccgt tcaacagccg atgtaatcac cccacctggt
     1681 cgaacttcct tgacatactt gaggttgatt ttcttgggaa tatagtgggt caaaaaatcc
     1741 gctcccatga cctcaaaaat ccagtccaag tatttactgt tattgacatg accattcata
     1801 tccaagtcgt aaaaacgaac atggtaatcc ttgctgatca gctcttccaa ggactcatac
     1861 ttcggtccac ggataagttt tttatcaaaa ttagactggt aaggagccac aatctcaggt
     1921 tcaacagcat ggacttttcg actgtcgcgg tccatgagaa caaaggtcgc catcatatgg
     1981 atgagctcct gccccgcttc attataaata gtaaagcgac ggtagcaaaa aagccgattg
     2041 tagctcaagg cttccgtttc gatggtaatt tcttccgcaa aacgaggcaa acgaaccacc
     2101 tcaatatcat attctgcgat aatccagacc agattatagt cttccaaaat ggccttatca
     2161 ctaactccca gttcaatcga ctgcatccct gaaacttgca gtgacagcaa aatcacatct
     2221 ggaagtttga tatgaccgtt catatcagcc atatcaaaag gaattttcat tttcatttga
     2281 taagttaagc ccatgatcct actccaaaat aaatcgttct gctacagtat ctcccaaaaa
     2341 gagacctctc tttgtcatgc gaacgtggtc accctcaatc tgcatgaggc cttgttgaac
     2401 caaatctctg acaatttctc cataaagtcc agcaaaagac tgtccaaatt tttcctcaaa
     2461 tcgcgccatg gaaaccccgg atttcttgcg gagtcccaag aacatttctt cttccatttg
     2521 ctccttttga ctcaggtgat cttctgtaat acaagcattg ccttcctcaa ccgcactgag
     2581 ataatgacga atgggaccat gatttttata gcgtactcca ttgacataac cagatgcccc
     2641 tgcaccaata ccatagtatt cagcattgtc ccagtacatg agattgtgac gactttcaaa
     2701 gccgggtttg gagaaattag aaatctcata atgctcaaaa cccgctcgct ccagctctgc
     2761 aatgatgtac tcaaacatct ccgcttctag ttcctcctta ggcagaggca atttcccacg
     2821 tcgcatccgg ttcataaaga ccgtatggtt ttctaaaatc aaactataca aactcatgtg
     2881 gggaatatcc agtccaatgg ctttagccac attttccttt acttgctcca tggtctgacc
     2941 aggcagagca taaatcaaat caatggagat gttgtcaaaa ccagccagtt tcaggcgatc
     3001 gatattttca taaatatcct tctccaaatg actgcgccca atctttttca acatcttatc
     3061 atcaaaggtc tggacaccta gcgaaacacg attgacagcc gaatttttca aaacagctat
     3121 cttatccgca tccaaatcgc ctggattggc ttcaatggtc aactcttcca agacagacaa
     3181 atccaagttt ttagtcaagc cattcagtaa cacctccagt tgcggagccg acagggctgt
     3241 cggtgttcca ccaccgatat aaagggttga caacttttca atatcataag aacgaaactc
     3301 ttccagcaga tgctctaaat agctgtcgac tggctgattt ttgatgaaga cctttgaaaa
     3361 atcacaataa taacaaatct gggtacaaaa tgggatgtgc acataggctg acgttggttt
     3421 tttctgcata gtaattatta taccacaaag actagattcc agataaaaat caccatcccc
     3481 agatacatag tccgtccgga gatggtgatg gtttattctt ctgttatatc aatcacaatc
     3541 tcttctgagt catcaagagc ttcggctttt tcttgccatt gctccttgag attatttaat
     3601 tgattttttg atgcttctgt cgcttgaaaa gcataggatt tagcttgagc aagtatactg
     3661 tccacagtga tttcacctga ctcaacctgt tcttttgttt tcagaacaaa atctgtagcc
     3721 tgctccttaa cttctgtcag tttttcacag acttgctcct tggcatactc cggatcttct
     3781 ctcaaatcat ctagaaaatc ttgagcctga ctgcaaactt gtttgccctt atcacttgtt
     3841 aaaaacaagg caagagctgc acctgaaacc gttcctaaaa ggattgagga taatttaccc
     3901 ataaggattc tcctttttta ttttttgaaa aatttacttg caagacgaag agctgacaga
     3961 cttgcaccag tcttgagtgt ttttgaacca gctgatgaag ctttcttgct caagacacgc
     4021 gcatggtcat tgaggtctga aacagataga gataaatctg caacagcact gaagagtgga
     4081 tcaatcgtag ccaccttgac attgatatca tctgccaaga cattgacctt agccaacaac
     4141 tcattggtgt gatgcaaggt cacatccaca tctgaagtca aggttttaat cgtcttttct
     4201 gtttcatcga tgacacgacc aagcttttgt acagtaatga tcagatagac caaaaagaca
     4261 atcaaagcta gggcaacaag aatatatgca acttctaaca tttagttttc ctcctctgta
     4321 atatagtaag gggccttctt tcgattttga taaataacga tcattatacc gagaccgata
     4381 aggacaactg acagccattg ggacactcga aggccgaaga acatgagact atctgttcgc
     4441 ataccttcga tgaccatacg accgaaacca taccaaatca agtaaaaggc cgtgatatga
     4501 cctcgtctga gactcttcca tttccgtcta aaaatcagaa tcaaagcaaa gccaagcaga
     4561 ttccatagag actcataaag gaaagtcggt tgacggtagc tcccctcaat atacatctgg
     4621 tcacggataa agccaggtag ataatccaga ttatccactg ttgcaccata agcttcttgg
     4681 ttaaagaaat taccccaacg ccccaaactt tgagcaatca taacgctagg cgccgcaata
     4741 tctagaaaat cccaagtatt gatgagttta cggtcagcaa agatatagag cacaagagcc
     4801 ccagttatca aaccaccgta aatggccaaa ccaccattcc aaatggcaaa aatctctcct
     4861 aaattctgac tatagtaatc aaatcggaaa ataacatagt agagacgagc tcctaaaata
     4921 gccaagggaa aggctactaa gataaaatct aaaatatcgt ctggtatgat cttctttcta
     4981 ggtgcttctt tcatggtcaa ataaaccgca agaatcaagc ctgtcacaat acataaggca
     5041 taccaacgaa tagctagggg tcctagttga atagcaattg gatcaagcat tttgcacctc
     5101 atttcgagcg atgagacttg tcagtcgttc gtcgaacaaa cgggtcgcat caaagcccat
     5161 ttccttggca cgataattca tggcagctgc ctcaatcaca acagagatat tacgacctgt
     5221 tttaactgga atacgaatac gaggaatggc tacgccagaa acttcaagtt cctctgcatt
     5281 gtttccaaga cgatcaaagg tcttatgcgt atcgtaattt tccaaataga cagcaagctg
     5341 aacctgtgaa gaatccttga cagcactcgc accgtagaga ctcataacat cgataatacc
     5401 aaccccacga atttcaatca agtgtttcaa aatttcagct ggttcacccc agagagtaat
     5461 ctcatccttg gcaaagatat cgacacggtc atcggctacc aaacggtgac cacgtttgac
     5521 aagctcaaga cctgtctcgc tcttaccaat tccactatct ccctgaatca agacgcccat
     5581 cccataaata tccatcaaga caccgtgcac actggtacgt tctgccaaac gagaatccag
     5641 atagctagat aactctccag ataaacgact ggtagctgca cggctggtta aaataacaat
     5701 cttacattct ctagcagcct ttaacatctc ctctggaacc accaaaccac gggcaacaat
     5761 gactgctggt gtctcaggta gaaacatttt tttcaaaact tcataacggc tgttggaagg
     5821 catgctgatc agataagacc actccttcat ccccaaaagt tgaatccgct ctggtgtata
     5881 gtagtcaaaa tagcctgtca tttcaagacc aggtcgcgta atatccgctg tattgatttc
     5941 cttttcaagc aattctggtt cgccatagac aatgtctagt ctaagctttt caatcacttc
     6001 ttttactaaa accgacatca tttcctcctt caaatgagtt cttctctcta ttatatcaaa
     6061 ttgtaggagg aagtttcaga tttttgcagg ctttggagta tttatttaaa agaaaaagga
     6121 ctagatttct ctagcctttc atttcaatta gaatttttta cgtttacgag ctacttctga
     6181 tttacgttta cgttttacag aaggtttttc atagaattca cgtttgcgtg tttcttgaag
     6241 agtaccagct ttagtaaccg cacgtttgaa acggcgaagt gcgtcgtcaa gagattcatt
     6301 cttacgtact actgttttag acattttttt cactcccttc aagttcaata tctatttcat
     6361 tctacacgta aaaggaataa ttgtcaagca aaaatgcggt ttaattttga ttttttcttc
     6421 catttataca agagttgaaa gcgttcaata gaacattgct tttttatttt tcgagtaagc
     6481 taagcgcttc agcatctgcg atgatggtta catcagggtg attttggagg ctacttgcag
     6541 gtaggttctc agtcactggg ccagatactg ttccggcaat ggcttctgct ttcgactcac
     6601 cgtaagcaaa aagaataata gacttggcat ccaaaatgtt tttaatcccc attgaaatag
     6661 cttgggttgg gacgtcttca atcttagcaa agaagcgtgc attggcttcg atagtagact
     6721 ggtcaagttc tactagatgc gtttgactgt caaatggagt accaggctca ttaaagccga
     6781 tatgcccatt gcgaccgatt cccaagattt ggaggtcaac tggatggtca gccaaaattt
     6841 ggttgtagcg ttcaacttca gcttcagcat tgtccttaac accacgaggc aagaaacttt
     6901 ctttaaatgg tttttggttg aacaagtttt cttgcatgaa gtaacgataa gactgtggat
     6961 tgtccccatc aaggcccaca tactcatcaa ggttgacact ggttagattt gaaaaatcaa
     7021 ggtcactctc aacaatttcc ttgtaaaatt caagtgggct acttcctgtc gcaagtccta
     7081 gagtttgagc tccattagcc aatttttcct tcaaaatctc aaaagcaact tttccacctt
     7141 gaacttggtt ttcaacttta ataactttca tcttttcatc ctccatttct gtctatattt
     7201 attatatggt atagaccaat ttttgtcaag tgaaaacgat ttaatttcta aaaaaagagc
     7261 gtccaaactt gaaacgtgtt ataatggata gtattagaac ttagaaagaa tgaacagata
     7321 tatgaataca gctgattttg atttccactt gccagaggaa ttgattgccc aaacgcccct
     7381 tgaaaaacgt gatgcctcca aactcctcat cgtcaaccgt gagacaggag aaatgcaaga
     7441 taaacacttc cactctatta ttgatatgct ggaacctggt gatgcccttg tcatgaacga
     7501 cacccgagtt ctccctgccc gcctctatgg tcaaaaagtg gagacaggag gtcatgtgga
     7561 acttctcctc cttaagaaca ctagtggaga cgagtgggaa gttctggcta aacctgccaa
     7621 acgcctcaag gtcagtactc gtatcagctt tggtgatggc cgcctcagcg ctgtcgttac
     7681 agaagaattg acccacgggg gacgcattgt ccgctttgaa taccaaggaa ttttcctaga
     7741 agtcttggaa agtctgggag aaatgcctct gccaccttat atccacgaaa aattagatga
     7801 ccgtgaacgt tatcaaaccg tctacgccaa ggaaagcggc tctgctgcag caccgactgc
     7861 tggtcttcac ttcaccaaag aactgctggc agaaatccaa gctaagggtg ttcatctagt
     7921 ctatctgact ctccatgtcg gactcggaac ctttagacct gtttctgtga ataatctgga
     7981 cgaacacgaa atgcactcag aattctacca actttctgaa gaagctgctg ccacccttcg
     8041 ctctgtcaaa gaaaatggtg gtcgtgtcat cgctgttgga accacttcta tccgcacctt
     8101 ggaaactatt ggttccaagt ttgatgggca aatccaagca gattctggtt ggaccaatat
     8161 ctttatcaag cctaggtatg ggtggaaggt cgtggatgcc ttctcaacca acttccacct
     8221 gccaaaatca actctggtca tgttggtttc tgcctttgca ggccgtgaat tagtcttaga
     8281 tgcctaccac catgccatcc aagaacacta ccgcttcttc agttttggtg acgccatgtt
     8341 tatttattga gaaagaattt ctctaaatct tctaatacca ataaatcgct aagatattat
     8401 ttcaaagaac atctacaatt gaaactctag ctagctatag aatacgccta gtacattgaa
     8461 attaaaatgc ttccccctag cttcgaaaat attgccatag attgcgttga ctctccaaat
     8521 tgattcatct atattttatt tcagcttcct atactttctt cgctgtttgt aaattaaaat
     8581 gcaagacaca tgagtagcac catatttgtt actcttatct gtcctctcaa gagactgtta
     8641 tgagttattt cagaatcatt cactactttg accctgactc tccttagtct caaaatcaaa
     8701 gacttatact cttcaaaaat ctcttcaaac cgcgtcaacg tcaccttgaa ttatatatgt
     8761 gaccgacttc gtcagttcta tctacaacct caaagcagta ctttgagcaa cctgcgacta
     8821 gttttctagt ttgctctttg attttcattg agtattaaac aaaaagtgaa caaatctgaa
     8881 ttctaatgta cagaagacta ggcttgttca ctttttggct ctataatatt tgtagtgggt
     8941 aaatccacta tagatattat ggagcctatt ttattgtaga aaaaaaatcc catatgacct
     9001 ataatgaaaa gcgacaaaac aactcattag aaagaatcat gtggaacaat tacattttat
     9061 cacaaaatta ctagacatta aagaccctaa tatccagatt ttagacatca tcaataagga
     9121 tacacacaag gaaatcatcg ccaaactgga ctacgacgcc ccatcttgcc ctgagtgtgg
     9181 aaaccaattg aagaaatata actttcaaaa accttctaaa attccttatc ttgaaacgac
     9241 tggtatgcct actagaattc tccttagaaa gcgtcg
//
LOCUS       DAVFJR010000060         9184 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVFJR010000060 DAVFJR010000000
VERSION     DAVFJR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.061"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(61..432)
                     /locus_tag="VU722_002014"
     CDS             complement(61..432)
                     /locus_tag="VU722_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU1772909.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(491..1924)
                     /gene="glgA"
                     /locus_tag="VU722_002015"
     CDS             complement(491..1924)
                     /gene="glgA"
                     /locus_tag="VU722_002015"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU1772910.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(1921..2727)
                     /gene="glgD"
                     /locus_tag="VU722_002016"
     CDS             complement(1921..2727)
                     /gene="glgD"
                     /locus_tag="VU722_002016"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: protein motif:HMM:TIGR02092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU1772911.1"
                     /translation="MKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLA
                     KKDISEVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKK
                     EHPEKLRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQ
                     KIYTKVKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLF
                     PRVVIGEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(2672..4060)
                     /locus_tag="VU722_002017"
     CDS             complement(2672..4060)
                     /locus_tag="VU722_002017"
                     /inference="COORDINATES: protein motif:HMM:NF012398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU1772912.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPTMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHIDNKTQRGPDNFPFLFETFWL
                     KPNGCPQLRCSY"
     gene            complement(4604..6883)
                     /gene="pulA"
                     /locus_tag="VU722_002018"
     CDS             complement(4604..6883)
                     /gene="pulA"
                     /locus_tag="VU722_002018"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU1772913.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AVNDAPVWKTFEMKRGNSYSHNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQIIRLKTKTDAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKERLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(6995..8953)
                     /gene="ligA"
                     /locus_tag="VU722_002019"
     CDS             complement(6995..8953)
                     /gene="ligA"
                     /locus_tag="VU722_002019"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU1772914.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRKLVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMESLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTIVADAALSGLTVVLTGKLKRLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(9046..>9184)
                     /locus_tag="VU722_002020"
     CDS             complement(9046..>9184)
                     /locus_tag="VU722_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1772915.1"
                     /translation="MPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKL
                     I"
BASE COUNT         2728 a         2039 c         1676 g         2741 t
ORIGIN      
        1 ttgacctggg gacttataat ttgtccaact aattttcctg ttaaaagacc ttctttgact
       61 tcaagctagt tggcagtgaa ataggcaata ccaagggatt ttgctaatct ctccaactat
      121 tggtgtaaat ccaccagaca ccagaccaac taggatgcca ttcttttgga gaatagagat
      181 gaactctggg acatttagcg atagatgaat tgagttgaag acgttatcaa agaccaaaat
      241 aggaagacct tccaacaagg acactctttt tcttaaactg ctttcaaaga ccaactctcc
      301 tcgcattgcc cgacttgtaa tctgcgaaat ttccgcctca tgacctgcct ctctccctaa
      361 aagatcaatc acttcttcta ggattaaggt tccatctaca tccaaaacac acaagccttt
      421 tacttgagac atcagttctc ctctctaaac agcctaaaaa tcgtatgaag tcatcatacg
      481 attttatcta ttaattaact aaactatggt acaagtcaag gtatgacttg caggctgtat
      541 cccatgagaa gtcactctcc atagcttgtt tttgtaggtt tctccaaatg tctggatggt
      601 ttctatacaa gtccaatgct gtttggaaag tccaatttaa ccaataagga gatagattgt
      661 caaagctaaa gccagtaccg cttccttcga ttggattgaa agcgcgaact gtatctcgca
      721 agcctccaac ttcatggacc aatggcaagg ttccataacg catagccatc atttgagaca
      781 agccacacgg ttcaaaacga cttggcatga ggaagaggtc acaagcagcg tagatttcct
      841 gagcaagttt gacatcaaaa gtgatatttg ttgatagctt gtctgggtaa atctgagcaa
      901 accatgagaa agctccttca aaggctggat cgccagttcc caaaagaaca atctgaacat
      961 cttcttgcaa gatatggtga agactttcga ccaccacatc aaaacctttt tgacgtgtca
     1021 aacgagaaac aattcccacc agtggaacgt ctgctctaac aggcaagcca actctttctt
     1081 gcaattttgc cttatttttg gctttcccag acaaatcttc ctgattgaaa tgatagtcta
     1141 aaagagcatc cgtctgagga ttataaagat cagcatcaat cccattcacg ataccagata
     1201 ctttaccaga ctccatttta agaatctgat ccaaattaca tccaaactga ctagtcataa
     1261 tttcatgagc atagctaggt gaaacagttg aaacacggtt cgcatagaga atacctgcct
     1321 tcatccagtt cagacagttg ttccatcgaa gggtgccatc agcgtaacgt tcaaagccaa
     1381 ctccaaacaa atcacccaac attccttctg aaaattgtcc ttggaattct aaattatgaa
     1441 tggttaaaac tgtttcaatg tcctcatagg cttgaatcca acggtatttt tccttcaaca
     1501 agaaaggaat catagctgta tggtagtcat gaacatggag aagatcagga ataaagtcaa
     1561 tcctttccat agcctcaatg gcagccagtt ggaaaaaggc aaagcgttct ccgtcatcaa
     1621 aatcaccgta aacatgacca cggaagaaat aatattgatt gtcaataaag tagaaggtta
     1681 caccatttaa tactgttttc ttaattccac aatactgtct gcgccaacca acgctcacct
     1741 caaaatgaag cacatcttca atctgacttc caaatttagc ctctaccata tcatagtagg
     1801 gtaaaatcac tgcaacttcg tgcccagctt ttaccagtga ttttggaaga gcgccaatga
     1861 cgtctcccaa accacctgtt tttgaaaagg gtgcaccctc tgctgctaca aataaaattt
     1921 tcatgaatga atatcctctg ttactttagc acctttctta accacaactg gatgttctgc
     1981 agttcctcga atcacaacac caggctcaac ttcaacccct ttgtccaaga tagcatattc
     2041 gacctgagcc ccttctccaa taacaacacg agggaagagc aggctatctt taaccaagct
     2101 atccttatgg acatgaatat tacgtgatag aacagaatta gctacttgac cttcaataat
     2161 actaccagag gcaaactgag aagtgcttac cttagatgta ttagcatagt aagttggctc
     2221 ttcgtttttg acctttgtat aaatcttttg gtttggtgag aaaagagaat agaatttttg
     2281 tgattcaagc atatcgatat tcgcttgata ataagattta acagagtgaa tattggctag
     2341 atagcccgtg tactcgtagg cgaaagctcc ctcttttaca gccaaatccc gtaaaacata
     2401 gcgcaatttc tctggatgtt cttttttagc ttcttcttcc aagtgttcaa tcaaccaagg
     2461 tgtatcaacg acaaagatat ctgtagacat attgaacgtt tcagctgttg acttgctatc
     2521 aaagagttta tgagaaagaa catggtctgt ttcatctaca tccaagattg catttacttc
     2581 tgaaatatct ttcttagcta gttttttata aactacagtg ataggctctt ttgttgtact
     2641 atgtaggtgg aaaacttggt tcaaatcaat gttaataaga acatcgcagt tgagggcaac
     2701 cgtttggttt gagccagaac gtttcaaaaa ggaatgggaa attatctgga ccacgctggg
     2761 ttttattatc aatgtggact gtacctactt caagtttttc agcaatttca aaggcttttt
     2821 tgaaatcatt tgtaaagact gatgattgaa ggccgaattc agattcgttg gcaaaggcaa
     2881 tagcttcctc tacactagcc acacgaatga ttggtaaaac aggaccaaat ggctcttccc
     2941 atgccacttt catatctttt gtaacttggt caaaaagcac tggccagaga agattgccct
     3001 cacgtttgat tggtgtaaga gcctgagcct ctttttcttg tgcatcctca atcaagctcc
     3061 aaatgaagtc ggctgaagca ttgtcaataa caggtgtaat atcagcattg tcaaatggat
     3121 caccaactgt taatttagaa acttcttcct gaagcaaagt agctaattta tctgctacac
     3181 tttcgagaac aatgacacgt ttaatggccg tgcaacgttg tcctgagtag ctaaaggctc
     3241 ccgcaacaat ttgcttggca gcatgttcca aatctgcatc ttctagtaca agagctgcat
     3301 ctttcccacc aagttccaac atggtaggac gcataccagc taaacgacca atacgttctc
     3361 caataggagt tgaacctgta aagttgatga agttgacttc tttgtgctca atgatataat
     3421 ccccaatttc tgaaccacga cctgtaatgg tgttgaaaac acctgccgga atccctgctt
     3481 cttcaaatgc tttagccaac aagagtccag aaatggaacc ttgtgttggt ggcttaaaca
     3541 tgaccacatt ccctgcaatc aaggcaggtg caattttaga agcagataaa ttaactggat
     3601 aattaaaggg agcaatcgct agcacgatac caactggttc acgacggaca acagccagtt
     3661 tgtttttact tgctgcctca aaaccaccac cttccattgc ttgtccagtg atacggagac
     3721 cttcctcagc agcataacga atcaagtctg ctgtacgcac tacttctcca attgctgctt
     3781 taatcccttt tgctacttct ttggcaagga tagtaccaat ttcttcctta tcgcgttcta
     3841 aaatagctgc tgttttatgt aaataagccg cacgttcaac tgctgataaa gctcgccatg
     3901 ctggcagggc tgcacgcgca gcttgcatag cctcatcagc ttcagtctga gtcatggctg
     3961 gaactgtacc caattcttct tgattgattg gtgaataaat cgtaatttct tgttcagatg
     4021 atttccattt tccatttact aaattctgat atcttgtcaa attctcatcc tcctgaaaat
     4081 gattaagata tattttacca aattttcaga aaatcacaac cctttttgca aaatttttga
     4141 gattattttc acaagcttga tttttcaaag tatactcaat aaaaataaaa aaaatccact
     4201 acgtcaaggc aaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     4261 ctatagtaaa ataaaaaact gaacaatttg gttggggaca accaaaccaa tttctcacaa
     4321 tgttttagaa acaagggtgt gctattccaa tttcagccta ctataactgt catagattgc
     4381 tgaaacaaag tctagataaa agtcttcata ataacaagac cccctatcca gtgttcaaaa
     4441 actttgatag gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct
     4501 gttagccaga ttctttctat tctttcaatt tcaataaatg gattttttac caatactcat
     4561 aactgggaat ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga
     4621 cagctagact aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca
     4681 tagctaaatt tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca
     4741 agaggcgttc tttgccgtga acttcataga taaggcagcc gctatgttca atcgcagaat
     4801 gcacaaagac atgatggtaa atttcatcat agctagagta agaaaaggca tcagtttttg
     4861 tcttcaatcg gatgatttga cggataaact caatactgtc ttgacgctca ttaatcaagt
     4921 tccagttcac ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat
     4981 catcatgggt caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt
     5041 gaccgatttc cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga
     5101 ccttgcgcat gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa
     5161 gattgtaatt gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc
     5221 ctaattcacg acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga
     5281 caaaacctga cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt
     5341 cattaaagaa accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag
     5401 gggcaagacc tgttcccatg tcccatcctt ctccatagag gataatgttg gagtcgattt
     5461 catccaagct ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa
     5521 aacggaagcc gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact
     5581 tgcgaaacat ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg
     5641 taccatctgg attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa
     5701 caactgagaa ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat
     5761 aagcttgaac catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg
     5821 aaaaactagt ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat
     5881 ttccatcctc atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt
     5941 agcccagctt cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag
     6001 cctgagcagc acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt
     6061 tagtcaaatc acgaatgtgc atttcacaga taactgcctt acatggattt tccaagcgcc
     6121 aagtagcctc cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca
     6181 gaatagctga acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg
     6241 tttggtgatg agggaattgg acttgatact gataagcctt acctaccaaa tcttcctcaa
     6301 catccaaact ccagacaccg attgtattgt ccttatgatt atgagagtag ctattgcctc
     6361 ttttcatctc aaaagtcttc caaacgggtg catcattaac agctgattca taaacgacaa
     6421 cttgcacttc tgtcgctgta ggtgaccaga gggaaaaatg agcctgattg tcctctacac
     6481 ggcaacccaa ttctccttgg taaccccaat gatgatcaaa actagcactg ttaatggcct
     6541 tatcaaaggc aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag
     6601 agtaataaat cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat
     6661 taaaacggat agaatattct ttactagttt gacctgtatg aaccacaaaa tttaagcttt
     6721 ctataacatg tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt
     6781 aggttagcaa atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc
     6841 cattcttacg atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt
     6901 tactttgttt ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag
     6961 tcatattctc taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat
     7021 ctctgacctg gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta
     7081 ccacgacgag gtcggtcttt ttagaaacac tacctgtcac tttggcaccc agactttcga
     7141 gtttactttt agcttctgag cgcttgagtc gtttcaattt tcctgtcaat accacggtca
     7201 aacctgacaa ggccgcatcc gctactatcg tctgtccttt atagtccaga ttgaccccag
     7261 tttctttcaa ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac
     7321 ttttggcaat cacgccacct agactttcaa tactggccac ttcctctgaa tctgcctgag
     7381 acagattttc aattgaatgg aaatattgaa gtaaaagctg actagccttg cttcctacat
     7441 gacgaattcc caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag
     7501 cctgatacag tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt
     7561 cttgcaaacg ataaatatcc gccacatcct tgactaaatt agcagcaaag agcttctcaa
     7621 caatagatgg accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc
     7681 tttccatgat ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa
     7741 agtgcaacaa gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag
     7801 aaacccgttt ggactctacc acacgtaaaa cggcagggat gatatcacca gccttatata
     7861 caatgaccgt atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg
     7921 tcgcacggct aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta
     7981 caacaccggt acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcag
     8041 cagggaactt gtaggctact gcccactttg gagccttaac tgtaaaacca agttcttctt
     8101 gacttgctag gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc
     8161 gttcctgtcc tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc
     8221 gcttaggatt gaccacaaaa cctagttgtt ctaggtactt caaccccttt tcttggctat
     8281 cacgagttga agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta
     8341 ctgctgtatc caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag
     8401 gctctccatt ttcttggcgc gcttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac
     8461 attccccacg aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac
     8521 gcttgaggtt ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa
     8581 ccaaaatccc cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa
     8641 tataggtcgg atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac
     8701 gtgaaaaagc atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat
     8761 ctaaaacctt gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag
     8821 cagtttctaa ctcgaccaac ttacggtaaa ggcggtcata ctcactgtct gaaaccgagg
     8881 gattatcgct ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca
     8941 ttcttttatt cataagacca ttttaccata aaacaaaccc tcctcacaaa cgagaagggc
     9001 ggaaaaaaca cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc
     9061 aaaatgagtt cgaacataaa taaacgatat acaagacaag atgataacac cacttccaat
     9121 tatcaggaaa gaagagagat gtacacttgg caagactgtc ataaatcctt ttgcaatagg
     9181 cata
//
LOCUS       DAVFJR010000061         8970 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVFJR010000061 DAVFJR010000000
VERSION     DAVFJR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.062"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(160..1782)
                     /locus_tag="VU722_002021"
     CDS             complement(160..1782)
                     /locus_tag="VU722_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU1772916.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGTY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLILIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYIKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFTVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            1888..3333
                     /locus_tag="VU722_002022"
     CDS             1888..3333
                     /locus_tag="VU722_002022"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU1772917.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYHYNSVVFDTICYDSRK
                     AKEKSLFFVKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMEHFSVLKEQAEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGHFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGRKESYPGDTAVAENYL"
     gene            complement(3376..3573)
                     /locus_tag="VU722_002023"
     CDS             complement(3376..3573)
                     /locus_tag="VU722_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU1772918.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(3674..4282)
                     /locus_tag="VU722_002024"
     CDS             complement(3674..4282)
                     /locus_tag="VU722_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU1772919.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFSMLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(4307..4819)
                     /locus_tag="VU722_002025"
     CDS             complement(4307..4819)
                     /locus_tag="VU722_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU1772920.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPAAFFESNHLYDLYVYPEMDIQSVKERACKHFGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(4906..5841)
                     /locus_tag="VU722_002026"
     CDS             complement(4906..5841)
                     /locus_tag="VU722_002026"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU1772921.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELVELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(5912..6211)
                     /locus_tag="VU722_002027"
     CDS             complement(5912..6211)
                     /locus_tag="VU722_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU1772922.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(6201..6950)
                     /locus_tag="VU722_002028"
     CDS             complement(6201..6950)
                     /locus_tag="VU722_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU1772923.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(7005..7364)
                     /locus_tag="VU722_002029"
     CDS             complement(7005..7364)
                     /locus_tag="VU722_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU1772924.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(7366..8766)
                     /locus_tag="VU722_002030"
     CDS             complement(7366..8766)
                     /locus_tag="VU722_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU1772925.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYM
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKLEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
BASE COUNT         2736 a         2036 c         1663 g         2535 t
ORIGIN      
        1 gtttggtttg tttagtcaat tattttttcc aaaaaatcga aaaaaactca ttttctattt
       61 ttgaaagata attttagcta ttttgacgct aaaaaaggaa taagttcaag ttctcctaaa
      121 agattgttca acttattcct tttatttata aatgctacct tacgaaagct taaattttgc
      181 tcgcaggcga tctgcttggg cttttcctat taccttatct aataaatagg tacgcagact
      241 cataaccata taaagtccac cccccatggc accgacaaga gctacataaa agaagctcca
      301 caaacgtcca cttggttgga agaaaaatcc taacagccac tggatggttc ctattaacag
      361 aaacatgact agggtcagca aactgattaa aatggttcgc ttcaaaatca ccttgcgctt
      421 gacaccagtt actttacaaa tatcccgata catcaagacg ttaggaatga tgagagcaat
      481 ggttgttgaa atcaaaggac cataactgtg gaagagggcg atggtaggta gttgcaagac
      541 tagcttggca atagaaccgt agataaaata gagaacggcc ttgcggttgc ggaacatggc
      601 ctgaagcatt ggagacaaga ccatatacaa gcctaaaata atagactgca aaactgtaaa
      661 gacaaataag cccatagcca aactatctgg cttaccatag aagaccgtat aaagaggttc
      721 tcctaccata accactccaa ccgttgctgg tagcaagaac ataaagagta gggtgagact
      781 gtcctgaacg agacgagaag ctgccttcaa gtcccccttg atatagtttt ccgtcaaaag
      841 tggcaaacca acactcccaa tcgaaacccc tacagaaatc aaaatcatcg tgattttatt
      901 aggattggct gagaaataag aaaacatgac aaccaagtcc tcattactgt agttggtaaa
      961 ccagctcata ctattgataa aggtcagctg atccaaaatc tgaaagagct ggatggcaga
     1021 ccctgtcagg ataaaaggaa tggcttcctt aatggtatca accaagagac gcttactgtt
     1081 aatcttatct cctgtttcaa agactctttt gagtgaacct tcttgggcaa ggaaataaat
     1141 caagactgca aaactggcta ccataccgac aaaggcagca aaggttgatt gggtaacggc
     1201 tgctagataa tctcctgaac cgagcttcat aatgataaag gttgctagga gcatccagat
     1261 aacacgaatg acctgctcag caatttgact catggcataa ggtttgaggt tattcatccc
     1321 ttggaaaaat cctcggataa cactcataga cgggaaaatc aagactcccc aagccaagct
     1381 ttgcatgatt aggatcaagt ctttgcccac gccagacaag tctgctagcc aaggagcaaa
     1441 gacatacaag actaaagcaa aaaccagacc tagtcctgtc ataaagccta agaagctccg
     1501 aatcagggca aagctatgct cttcttctcg catagtatta tacttggcaa cttgcttggc
     1561 caccgcaact ggaatccccg ctgttgaaac caacaagaac caagcataga tattgtaacc
     1621 catggtaaag agaccatttg ccttagctgc ataagtcccc atccagatgt accaagggat
     1681 aatgtaaaca gccccgagta ggcgactgat aaagttacta gccgttagcc aagcagtccc
     1741 ccgtaacatc tgagcctgct ggtgattgtt ttcgtgcgac atagattcct cattcaattt
     1801 tgataactag gaaaaactcc ttatcttcca ttataaactt ttccttgtta cttgtaaatt
     1861 tgcgactttc ggtttacaat agaaagtatg ataaaaattg aaaccgtatt agatatatta
     1921 aagaaagatg gtctcttccg cgagattatc gaccaaggac actaccacta ccactacaac
     1981 agtgtcgtct ttgacaccat ctgctatgac agccgcaagg ccaaagaaaa gagcctattt
     2041 ttcgtcaagg gcgctgcctt taaaaaagaa taccttcttt ctgctataac acaaggctta
     2101 gcttggtatg tagctgaaaa ggactacgaa gtcggtatcc ctgtcatcat tgtgaacgat
     2161 ataaagaaag ccatgagttt gattgccatg gagttctatg gtaatccaca ggaaaaactc
     2221 aaactccttg cctttactgg tactaagggt aagacaacag cagcctattt cgcctataac
     2281 atcttatctc aagggcatcg acctgctatg ttgtcgacca tgaacacaac tcttgatggc
     2341 gagactttct ttaagtcagc gttgacaacc cctgagagta ttgacctctt tgacatgatg
     2401 aatcaggctg tgcaaaatga ccgtacccac ctcatcatgg aagtctccag tcaagcctat
     2461 ctggtcaaac gtgtctatgg tctaaccttt gatgtgggag ttttcctcaa tatcagccca
     2521 gaccatatcg gcccgattga acaccctagc tttgaagact atttctacca caagcgtctc
     2581 ttgatggaaa atagccgagc agtcatcatt aacagtgaca tggagcactt ctcagtcttg
     2641 aaagaacagg ctgaagatca agaccatgat ttctatggta gccaatttga taaccaaatc
     2701 gagaattcca aagcctttag cttttcagct acgggtaaac tcgctggaga ttatgatatc
     2761 caactgattg gtcacttcaa ccaagaaaat gcagttgctg ctggacttgc ttgtctccgt
     2821 ctcggagcaa gtcttgagga catcaaaaaa ggcatcgctg caacccgcgt tcctggtcgt
     2881 atggaagtcc tcactcagaa aaatggagcc aaggtcttca tcgactatgc ccacaatggg
     2941 gatagtctga aaaaactcat caatgtggtt gaaactcatc aaaccggaaa gattgctctg
     3001 gttctgggat caacaggaaa caagggagaa agtcgtcgta aggactttgg cctcctcctc
     3061 aatcaacacc ctgagattca agtctttctg actgctgatg accctaacta tgaagaccca
     3121 atggccattg cagatgaaat tagtagctac atcaatcatc ctgttgaaaa gattgcggat
     3181 cgccaagaag ccatcaaggc ggcaatggct atcacaaatc acgaattaga tgcagttatt
     3241 attgcgggta agggagccga ttgttaccaa atcatccagg gcaggaaaga atcctaccca
     3301 ggagatacag ccgtcgcaga aaattattta taagaataga aaaaatcaag ggaaaatgaa
     3361 acccttgatt ttttcctatt ctttagtaaa aacgtttttc aaaccttcaa cggcaccttc
     3421 tacagcacct tttgcgtctt ctacaacgtc ttttgcctta gcaactgttt tttcaacagc
     3481 tccttcaagt tctgtcttgc tgtctccagt aactttacca aaaccttctt tgacagcgcc
     3541 tgttgcttgt tccaatttgt tttcaagtga catatgattg tctcctttag tttattccga
     3601 tatgtgttac cggttacata tagtttatac cgaatactaa ggaaagtcaa acaatgtgct
     3661 cagaaacaag aaatcacgct aagtagaaag ttaatctctc cttatcaaaa tcgatagcca
     3721 actcatactt tccatcttca ttttgcacaa tatagcctaa gacaaccaaa ctgtccacaa
     3781 agatatcacg gcatttctgc ataagctggt cttttttgag aaatttcaac aaaaaagccg
     3841 tcatatactt gagggcatac tcaggattaa catctcctaa aatgtcatag agctcctgct
     3901 gtttttctgt caaaggatac tgctgtttga ccttgtaaaa ataattggac agggtcattt
     3961 taatgcgcgc aaagtccgtc ttttcaacta aaatagctgc attgatttga ttgcgcaatt
     4021 ccgtctcaaa actctgctcc aacaaggctt gatagaccgg actagcttct ctgacaaaaa
     4081 tctcttgatc cagttcaaga ctatcaagtg attcaagcat agaaaaattg aggtaatagc
     4141 gtttattttc acgtagaatc aagcctgcct ttatatactc ttccatgagt ttatcaactg
     4201 caacatctgg aaattgagcc ttaatttccc gtagaatcac atcctcatac tggtccagat
     4261 atcggatcaa ttctccaaaa atggctgtct cgtcaaacga gatggattaa aaatctgaat
     4321 catgaagatt cctttcttta cattgtaaca gaggcgatgc tgccaactga ctaggattgg
     4381 taccagcttg gttcagagga acaggcagac ctagttctat gtaatactcc ctccaaaaat
     4441 cactaatctc ctgctcccca tctccaaatt tcataggaat agtttcaaaa ataggtagga
     4501 tttctgctat atactgggag cagtagaaac cagctgcatc tggatagaaa gaagcattgt
     4561 agggtgctcc aaaatgtttg caagctcttt ccttcaccga ctggatatcc atttctgggt
     4621 aaacatagag gtcgtacaaa tgattggact caaagaaggc tgccggttct tgacagacaa
     4681 caccagcctg tccactagca tgataaatca tcccatccaa ataaatggca acatggctat
     4741 agttacctgt ggaagtctgg atggcctgtc ccatgtctga cccatctctc acaaaaatca
     4801 aatcaccatt ttctaacata cttcactcct agaaaaaaag gagccgaaac tcctttcgat
     4861 ataaggcaaa ctagcctttc cgattttgag ctgacaccca aaatcttacg cattaaagct
     4921 ttcagtcaat tgaggtacca cttgtttctt acgtgaaacg gcaccagcaa ggaaggcatg
     4981 attgttttca agtttgaagt tgaaagccgc ttcgaccttg tccatattgg caccaagagc
     5041 caagatttct gagtttgagt tgacgatatc tgtaatcatc aagacaaagt cagagtagcc
     5101 gtttgattcg ttggcagctt gcattgcagc ttcaatttct gcttggcgtt ccaaaacttc
     5161 agcgatgtca actgtgttca cttgggcaac acggacatta tttccgttga gttcaaaagt
     5221 cttagcatcg atgtcaatca attcttcagc agatttgcta gccaagttgg taccagcttt
     5281 caacattgcc aaaccatatt cttccaagtt cacaccagcc aattcaacca attcaggagc
     5341 aatgatttta tctgttgggt gtgttgttgg tgatttcaaa agaagggtat ctgaaatcaa
     5401 acctgaaagc atcaaacctg caatctcttt aggcacagct acaccatgtt ctttgaacat
     5461 acggtaaacg attgaagacg ctgatccaac tggctccaaa cgcatgtaaa gtgggcttgc
     5521 agtttcaaag ttagccacac ggtggtggtc tacaacaccg taaacttcta cttcagcgat
     5581 atctgataca gattgttgga attcattgtg gtcagtcaag ataacttgct ctgccccctc
     5641 tgctttggca gaagtgataa cacgtggtgc ttccacacca aaatagttca agacaaaggc
     5701 tgtttcttca tttggagttc caagggcaac agcttccgta tccaaaccgt aagcttcttt
     5761 tgcaaggtag gcaaaagcta cagatgaccc gatggcatct gagtctggat tttggtgacc
     5821 aaatactaga atcttggaca tggtaatacc tcattttgtt tattttcttt attgtagcat
     5881 ttttttcgct ttttgacaaa ggtaagagga gtcaaaggac tccccacgat tcttcaaaat
     5941 aactgagtaa atttctatct tgattttcag ataaaaattc ttccttctgt ggcctcttct
     6001 tacgcttgag aagagcctca gccgacatgg cttcttcctt actggcaaaa ccttgagcat
     6061 agataagttt gactggcaag cgtgctcgtg tatatttggc tcccttccca ctattgtgga
     6121 tagcgaggcg tcttctcaca tcagtcgtat agcctatata gtaggatcca tcacgacact
     6181 ccagaacgta catataagcc ttatgatcca taataaatct cttcgatttc gggcgtataa
     6241 gagccatcat cattgtggac aatcaaagga ggtaagacct taaagccact tgttgagcca
     6301 tccttgatcg cctcaatcaa aagcatattg gcttcctttt ctctttttgg ataaacaaac
     6361 tgcaggcgct taggggctag attatgtcgt tttaacgtat ccaaaatatc cagaagtcga
     6421 tcaggacgat gaaccatggc caaacgccca ttagacttga gaatactctg ggcactacga
     6481 cagatttctt ccaaattagt cgtgatttcg tgtcgagcca agagataatg ttcactctcg
     6541 ttcagattag aataaggatc caccttgaaa tatggtggat tacacaaaat catatccacc
     6601 ttactcccct gaatgtgagc aggcatattt ttcaaatcat cgcagatgac ctgcatttgc
     6661 tcctctaatc cattcaaacg gacagagcgt tcagccatat ccgccaaacg ctcctgaatc
     6721 tcaacagaca atatctgtgc ttgagtacga gtgctagcaa aaagccccac tgctccattc
     6781 ccagcacaga aatccacaat caaccccttc ttaggaaaac gtggaaatcg tgataagaga
     6841 acactatcca ccgaatagct aaaaacctct ctattttgaa tgattttgat atctgtcgaa
     6901 aagagctggt taatgcgctc tcctgatttt aataattgtt cttcttccat ggtcctatta
     6961 taataaattt atattaacat tacaaaaaaa tataaaactc taaactactt cttctttttt
     7021 aaatggtgca gagcttctcc agtccagatt ggtagcattc gtcgaaaggg agcaaaaccg
     7081 tagttaaagc ggtcgcttga aaagcgtctc cgtctaggaa actggtactt ttcttcctcc
     7141 aaagtgcgga tagaaagact ggctttcccc gtaaattcat ctaaatccac tacctgaact
     7201 tgaacctctt catcgacttt caaggtttca tgaatatttt caataaatcc tgtccgaatt
     7261 tctgaaatgt gaatcagccc cgtatcaccc gtctctaact caacaaaggc accgtagggc
     7321 tgaatccctg taatacgccc ctttagctta tcaccgattt tcatcttagt cctcgatttc
     7381 aatagtttca attacaacat cttcaactgg cttgtccata gctcctgtct caacagcagc
     7441 aatggcatcc aagacagcgt aagatgcttc atcagctaac tgaccaaaaa ccgtgtgacg
     7501 gcggtctagg tgaggtgtcc caccttgatt ggcatagatt tctgcaatcg gttctggcca
     7561 accaccacga gtaatttctt tcttcgaata aggtaggtgt tggttttgca cgataaagaa
     7621 ctggctgccg ttggtatttg gaccagcatt tgccatggaa agagcaccac ggatattgta
     7681 aagctcttct gagaattcat cctcaaaaga ttcgccgtag attgactcgc cacccatacc
     7741 agttccagtt gggtctccac cttggatcat aaagtccttg ataatacggt ggaaaatgac
     7801 accatcatag tagccatctt ttgaaagaga tacaaagtta gccactgttt taggagcatg
     7861 ttcagggaaa agcttgatac gtaagtctcc gtgattggtc ttaatagtcg caagaggacc
     7921 ttctactgtt tcaatatcta cttgtggaaa atgcaattct ttttctacca taccaaatac
     7981 ttctaaggca tcaaaaatgc catcttcttc taatgttttt gtaatataat ctgctttttc
     8041 tttgatttta tcatgagaaa ttcccatggc aacgctgatt ccagcataat caaagagttc
     8101 caagtcattg agaccatctc caaaaaccat gaccttctct agtttcaagc caaggtgttc
     8161 cacaaccttt tccacccccg tcgctttgga gcctgaaatc ggcacaatat cagacgaatg
     8221 ttgatgccaa cgaaccatgc gaagtttgtc tgagagactg tcaggcaagt gcaagtcatc
     8281 tcccttatct tcaaaagtcc acatctgata gatatcttct ttttcatgga aatcgggatc
     8341 tacatctaag tcgggataaa ttggattgat agcttcactc atcatatcgg tgcgagtcga
     8401 caacttggca tcatgactcc caaccaagcc atactcaatt ccttcttgct tagcccaaga
     8461 catatactcc tcaacatctg acttttcaat ctgatgctga taaatgacct gacctttttt
     8521 atcttcgata taagccccat tcaaagttac aaaaaagtca ggcttgagat cacgaatctc
     8581 tggaacaaca ccaaaaatgc cacgtccaga ggcgattcct gttaaaattc ctttttcacg
     8641 caactgttta aaaacagtgg gaattgtagt tggaataaac cctgtctttg aattccgcaa
     8701 tgtatcatca atatcaaaaa agacaatctt gatcttcttt gccttgtatc ttaatttcgc
     8761 gtccatctca ctacctcttt caatctaact ctttccatta tatcataaag taggcaaatc
     8821 ccctattttc aaaaagttta tcatttttat tttaatttct tggatgagaa aagagacata
     8881 tttatgaaaa agtccaacca aattcaactc gacttctcat tccagaactc gtaaaaaaaa
     8941 acctaatatc cagattttag acatcatcaa
//
LOCUS       DAVFJR010000062         8691 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVFJR010000062 DAVFJR010000000
VERSION     DAVFJR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.063"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(100..582)
                     /gene="greA"
                     /locus_tag="VU722_002031"
     CDS             complement(100..582)
                     /gene="greA"
                     /locus_tag="VU722_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU1772926.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVIIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVDSYDVKILKVEKTA
                     "
     gene            complement(653..2308)
                     /gene="mltG"
                     /locus_tag="VU722_002032"
     CDS             complement(653..2308)
                     /gene="mltG"
                     /locus_tag="VU722_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU1772927.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPRPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVTSFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRNR
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2389..2883)
                     /locus_tag="VU722_002033"
     CDS             complement(2389..2883)
                     /locus_tag="VU722_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772928.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2880..3344)
                     /locus_tag="VU722_002034"
     CDS             complement(2880..3344)
                     /locus_tag="VU722_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772929.1"
                     /translation="MEIPIKIIQASKSDLPEIEALQTSSFPAEKQQPSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEDATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3354..4688)
                     /locus_tag="VU722_002035"
     CDS             complement(3354..4688)
                     /locus_tag="VU722_002035"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU1772930.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADKNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLKDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFESEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFVHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4700..5317)
                     /locus_tag="VU722_002036"
     CDS             complement(4700..5317)
                     /locus_tag="VU722_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU1772931.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5365..8463)
                     /locus_tag="VU722_002037"
     CDS             complement(5365..8463)
                     /locus_tag="VU722_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1772932.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSGCAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPTLFMEDYQ
                     GVSGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8556..>8691)
                     /locus_tag="VU722_002038"
     CDS             complement(8556..>8691)
                     /locus_tag="VU722_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772933.1"
                     /translation="AKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC
                     "
BASE COUNT         2373 a         1980 c         1664 g         2674 t
ORIGIN      
        1 tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtagca aaacagaaaa
       61 aggagtgagt gaagcgcatc gccactcctt tttctgtttt taggctgttt tttcaacctt
      121 caagattttt acatcatagc tatcaacagg cgtttcaatg gttgctgtgt cacctgtttt
      181 cttgccaatc aaggcctgcc caattgggct ttcatttgaa accttacctg caaaggcatc
      241 cgcaccagct gaacctacga taatataaac ttcttcttcg tcctcaccaa tttcttggat
      301 gatgactgtt ttaccaatcg ctacttcgtc ctgggcaact gcgtcgctat tgacgatttc
      361 agcatagcgg atttttgttt ctaagctaga gatttgtcct tcgacaaagg cttgttcatc
      421 cttagctgct tcgtactcac tgttttctga aaggtcaccg tatgaacggg caatcttaat
      481 gcgttctacc acttctggtc gacgaaccaa tttcaattct tctaattctt tttcaagttt
      541 ttccttttcc tcaagggtca taggatatgt tttttctgcc atttttctca actttcttct
      601 gataatattt tctaaagaaa attatgtgaa gtatcacata attttagttt gtttagttta
      661 atttgctgtt gacatgttca gcgacattgc ggtcgtggtc ttcttgattg ttagcatagt
      721 agaccttgcc ttctgtgaca tctgctacaa agtagaggtt atcgctctta gtttgattga
      781 tgcttgactc aatcgcatcc agacttggac tatcgactgg accaggcatg agacctacat
      841 ttttataaac attataaggt gaatcaatgt tggtatcaat cgcaacatcc tcagctagac
      901 tgatattttg ccccagtttt ccttgggcat acaagattgc aatattactt tgaagtggcc
      961 tattacgatt caaacgattg tagaatacac ctgcaatgag cttacgatct tctgtcttgg
     1021 caccttcttt ttcgaccaag gaagcaatgg tcaacaactc attgacagtc aagtttttag
     1081 atttgatagt actatagtaa ggagataggt tcttatccat agcagctaac atctcatcaa
     1141 tcaagctctc aatagttgtg ctttccttga tagagtatgt agctgggaaa aggtatcctt
     1201 ccaaacgata acgcgcaccg ctgtctttta caggcaaact ttccagtaaa gtaggatatt
     1261 tagctactgc ttgactgata aacgtctcat cttgaacttt agccaagaaa gtctccgctg
     1321 tcaaagactc tttgaagtca ccttgcaatt gacccacagc ttgagcaatc tgatccaagg
     1381 tataaccttc tggaattgtc aaagtcgcaa gtacaggttc ttgcggttca tctgttccac
     1441 ctttttgcaa ctctttgagt aagtcttctg tactcatact cttttgcaaa ttgtagtaac
     1501 ctgctttcaa gtcggtataa tttttatact tggcataaaa actaaaaatc agaccatgct
     1561 ttaccaaacc agctttttca agcgtcgtac cgatttcttg aacgtttgaa ccttctggaa
     1621 ttccaaccgt cacatatttc ttagaattag catcgatagg taacaaagaa tctagcacgt
     1681 actggtaacc aaagtaacca cctgctgaga gcaaggcaag gaatacaagg aatgaagtca
     1741 caaaagcttt cacatgtgac ttcttctctt tcttaggctt aacgggtttt gctccttctc
     1801 tacggctacg acgtgatgta tcgctgatga tatccactgt ttctgtagca ggcctaggtg
     1861 tttctggacc tgcttgttct gcttttttct ctgccgtcgt ataggaaaca gctacccttg
     1921 ttggggtttc attgtattct ctttcaagtt tcttaggtct aacaggacct ggacctggtc
     1981 ttgatccact ttcttccgct ggagaagaag gtacatcttg acttggatga cttggaacac
     2041 caggagtttc tctttgaatc tcatctgctg gagaagctgg tacaccttga cttgggtgag
     2101 taggcacggt aggagctttt ctcataatct cctctaccgt tgacaaggaa tcagccatga
     2161 gttcctcagc tgaaggttca tttgcaggag tgcgaactac tgcctcatct tctttcagaa
     2221 cttcatcata gccttttact ttttctaaat ctctcagaat ctgctcttta aagcttaatt
     2281 tctcttcttc tcttgacttt tcactcaaaa gtttttcctc cttgttgata atccataata
     2341 ttatatctta aaagtcaaaa aaaagcaatc tatgatactt ttcctaactt attttttcat
     2401 ttcccagacc atatcatacc atgtttcccc tgcaaaggtt gactgggact ggccttcgtt
     2461 gacaaatcca tgtttttcat aataggcgat gagatagtca tgacaggtta gattaatgcc
     2521 atctctctca tcttcaagag caacttcttt caaggctgtc agcaatttct gacccagtcc
     2581 gagtccctgt gcctccttgg caatagacag acaggtcaca gagatataac caccaggctc
     2641 atgactatag tcttttattt cttctgtaaa agactggtct tgcagatggc ggtgcaggcc
     2701 aactggtcct tcgatataac ccatgattct tccttctttt tcagcaacca gaaaagaggt
     2761 ctgaatttct ctcaaatgtg cttcaaagac agaaggagga atggcttctt cgaccgaaaa
     2821 attttcaaat tcaagttcaa caatccgatc caaatcttct aatcttgctt gtctgatttt
     2881 cattgttcct ccagataaaa gggattaaac caaatcatac tatagccctg gctagttgca
     2941 tagagcaaag ttgcgtcttc atcaacaaaa ccgttcattt caaaatagga aagcagctca
     3001 tcaggactct ccaaacgaat ccctttgtaa tccagctcaa ctgccacctc tttcaaggct
     3061 gcaagaagaa gtgttcccaa gccctgtctc tgatggtcag actcgatgac taaagaatgt
     3121 acttttagat attgcggatt gtctgactgg ggacttgata aaatatagcc taaaagttga
     3181 ttttcatccc tagctagaag aaaggtatcc gcacacttac ggatactttc ttctaaaata
     3241 tgggaaggtt gctgcttttc agctggaaaa gacgaggtct gaagtgcctc tatctcaggc
     3301 aaatcagact tgcttgcctg aatgatctta attggaattt ccatgggaac atcctattga
     3361 acattgcttg tcaagttaga caagagacgc tcaaatgagt attcataggt ttggatgtct
     3421 cctgctccca taaagacgta aacagcattg tcatggtcta ggagtggaga aacattttca
     3481 acagtaatca cttggtgttt tttgttgatt ttgttggcta ggtcttctac cttaacgtca
     3541 ccatgatcta cttcacgagc cgagccataa atttgcgcta gataaacagc atctgcttgg
     3601 tttaaagcat ggacaaagtc gtccaacaag gcaatggttc ttgtaaaggt atgcggttga
     3661 aagactgcta caatttcctt gcttgggtat ttctgacgag ccgcatccaa ggtcgcaata
     3721 atttctgttg gatggtgggc aaagtcatcg ataatcactg tatcattgac aattttctca
     3781 gtgaaacgac gtttaacacc ggcaaatgtt ttcaagtgct cacgcaccaa gttcaaatca
     3841 aatcctgctg tgtaaagaag accaataacg gctgtcgcat tcatgatatt gtgacgacca
     3901 aaggttggaa tgtggaattg ccccaagttt tgtccacgga aatgaacagt gaaagttgaa
     3961 ccagttgttg aacgaagaag atcactagct acaaagtcat tgccttcaga ttcaaaacca
     4021 taataataaa ttggtgcatc agacgtaatc ttacgcaatt cagcatcttc accatagaca
     4081 aaaagaccct tggtaatttg tttggcatag tcgttaaagg cattgaaaac atccttgaga
     4141 cttgtgaaat aatctggatg gtcaaagtca atgttggtga taatagagta ttctgggtgg
     4201 taaggcatga agtgacgctc atattcatca gattcaaaga caaaatattt ggcattggcc
     4261 gaaccacgac ctgtcccatc tccaatcaag aagctggtat ctgtaatgtg agacaagaca
     4321 tgagacaaca tacctgtcgt tgaagttttt ccatgtgctc ctgctactcc catgctaaca
     4381 aagtcacgca taaagctacc tagaaactca tggtaacgtt tgtagctgat accatttttg
     4441 tccgcatagg caatttcgac gttgttatct ggacgaaagg catttccagc gataatttcc
     4501 atatcaccgt ctagattctt ttcatcaaaa ggaagaatgg taattcctgc ctgctcaaga
     4561 ccgcgttggg taaagtagta cttttcaaca tctgatccct gaaccttgtg ccccatctgg
     4621 tgcaacatca aggccaaggc actcatccct gatcccttaa ttccgataaa atgatatgtc
     4681 tttgacatgt tttctccccc tattctgtca ttctggtcag attcaactct tgggcaaccc
     4741 gacgttcttg ttctgtttgt ttactttttt tattgtagat ttggctcttc tttagaaaat
     4801 cataattgtt tttctttgga gcaggtgctg acacttcttc attcttggta gggatagaat
     4861 gaacttcttc cgccaagata taatgagact gggtcaattt ttggctatat ttgacaaatt
     4921 caccaggatt ttccttttgg aaaggagttg tcggttgatt gccctgtcta actagactgg
     4981 gctgagaatg acgtctcgca aggctgaaat cctgagttag gtagttagca gagcgtttct
     5041 ttttcaagtc cgcacgcgct tcttcacgcg ccacctccgc atagctcttt ccttcttttt
     5101 taacccctaa aggagccttt ttaggtttct cgacttgctt ttcaatcggt tttactggtt
     5161 tttcttcagc aataggagcc cattctaaat aatttttatc tcgatactca cccttgatat
     5221 tactgatcag atcagactca tcatagagat tcatgactgg catttcagtc aacatgacct
     5281 cgtcatctga caccaatgga aatcgttctt gtttcatttt ctatttcctt tcaacacttc
     5341 attatagcgt attgtcttga tttttcaagt gctggcttca gaaattccca aaatttctct
     5401 aatttctgct agggtcagac taccacgtga ctctgtgccg tccaatactt gtgacaccag
     5461 atgtttcttt tgttcttgga gttcctgaat tttttcttca atggttccct tggtcaccaa
     5521 gcgatagacc tcaaccgttt cttcctgacc catccgatgg gcacggccaa tggcttgcgc
     5581 ttccaccgca ggattccacc aaaggtcaac caagatcact gtatctgcac ctgtcaggtt
     5641 cagaccgacc ccaccagcct tgagggaaat cagaaaggca tctctttctc cttgattaaa
     5701 ggccttggtc atgtcttgtc tttccttggc tggggttgaa cccgtaattt taaaggaagt
     5761 caggcccaag tctggcagtt cttgttcaat tttttccaac attcccttga actgagagaa
     5821 aatcaagaca cggtgtccgc cgtctgccac ctgtaccagt aggtctcgga gactatctag
     5881 tttgccactg actccctgat aatcttccat aaacagggta ggagtgtcac atatttgacg
     5941 caagcgcatc aaaccagata aaatttccac acgacttcgc tgaaattcct gttctgacac
     6001 ttgagccaga tggtctcgca tctgttgtaa ctgggcaagg taaatagcct tttgctggtc
     6061 ttccagttca tttttataaa ccacctcaat caagtctggc aattcagtca gaacttcttc
     6121 tttcttgcgt cgcatcacga aaggcttgat aaactgagcc actcgctctg ctggcaattt
     6181 cataaattct ttcttgcttg gcaaaagtcc gggcatgacg atttggaaaa tagaccacag
     6241 ctcacccaga tggttttcaa tcggagttcc tgacaaggca aagaccgacg gcaccacaaa
     6301 ttgtctcaag gtctgggcaa tcttggtctg ggcatttttc atgacctgag cctcatctaa
     6361 gaaaaggaag tcaaaggcca tcccctgata aaactcactg tcctgacgga aggtggcata
     6421 gctagtcaca tagatttgat ggctctcggc aagaatctcc tcacgacttg ctttcaaacc
     6481 atgaacaaca gccacatcca actgtggagc aaatttctga aactcatctg cccagttgta
     6541 aatcaaacct gacggagcga gaatcaaaac ccgactttct tttgtcactt gactagtcaa
     6601 aaaagcaatg gtctgaaggg ttttcccaag tcccatatca tcagccaaaa tcccaccaaa
     6661 accataatga tggagcatct gcaaccagcc aattcccttt tcctgataat ctcgcaagtc
     6721 agcctgaacc tgagttgcct gtcgaggaaa gtcctctgga tgtgtcaaat cctgggccag
     6781 attctggaat tcttgtgaaa aagaaacacg gtctcgccct tcaaagagat gagctaaact
     6841 gtaggccaag gatttcctag cctgcaaagt cccatctttt aattcaaatt gccccagttc
     6901 ctgtaaattt tgacgaattt tcttggtttc ttcatcgaaa aagtaaactt gattagacga
     6961 atcaatataa aaatcctgat tggcaaccaa ggcctgcatg gcttggtcga tttcctcctg
     7021 ggcaatatct tgaaaatcaa actggatttc caagagacct cccttggagg caatctgcac
     7081 ctgaggactc gctaggctat aaagctcttc tagtttatct gataggtcaa catgcccgag
     7141 tttttcaaag actggaatga tatcatgaaa aaaatgatag acagactccg cttttaaggc
     7201 ctgacgccaa gattgaaaat cggcttcaaa gcccgcagcc aaacagactt ggaaaattct
     7261 ttcttctaag tccgcgtcac ttgaaaatgg taattcttct agctcttgtc ggctagatac
     7321 ctgtctattt ccataatcaa actgaatttc taaacgaatc cgattatctt cttccctgtc
     7381 aaagtaaaaa gagggcgcaa aagttttgat ttgtagacgt tctggagctg aaacggtgcc
     7441 catctggata aaaagagtca gacaggaggc caatttgtct cgatcactgc tatcaaattg
     7501 caggtatttc tttccttgtt gacccacagg taacgcttta atttccttga gaagacgcat
     7561 ctgctggtct gttaaaaaat aaacctgacc tttatggaaa agtactgctc cttgataaaa
     7621 gacattgacc ctaggactct cactgatttc catttcaaaa tagtccgagt attctgttac
     7681 tgtaaaggca aatagattgg catcagcatg catatcctga aaaagcaggg tttggtagct
     7741 atccacttga tggtcaaatt gaaaatgggg caaggccatc agtaaattca caccctgctc
     7801 aaaaaaggtc agagggaaaa agaggtgccg accttggttt tggaaaaaga ggtctggaac
     7861 cagcccttcc tccgttagtc cgtgcaagaa agtcaaaagt tcttggctgg catcatcaaa
     7921 ggcttcccaa gaaagagact cctcataaat cttgccaatc atatacgact ttctctgctc
     7981 gacaatcctt aaaaaaagtg gaatatcccg aatgacatag tatttttggc tattgatttg
     8041 gccgattctc agagtccaca agatatgatt ggttcctgct tccacctgac ccacagctga
     8101 taactcatag gcgcatcctg attttggaga taaaattcga tccaaaaact tgccacccaa
     8161 ggtcaccttg gtttcaacgg cctctttttc ttcatgacct tcttccagac tccacaagat
     8221 ttcctgacca cgctcatcat tttttagaaa atgctctagc gctgccaaat gcacacagta
     8281 gcccctcttt tgaaaaaaat cacaggcaca aaaaaccaaa tcatcctcta aactatagcg
     8341 cagttcttct tctgcaacgc gagcgtagag tcgattgttc ttttccttga tgatatcaac
     8401 cttaccagtt tcataaaggg caacaccttc gatacgaatt ttccccggaa tcaatttagc
     8461 catattttca cctttacctt atctgtttat tataccatat tttcgcctat gaaaatagcc
     8521 ttctaggaag acttttctcc tagaaggctg gatttttaac atttggcaaa agtagccaca
     8581 atccgctgac agacttcttg caacagagat ttgggcatag ctatattgat gcgggcatgg
     8641 agacttcctt cctctccaaa atccaaacca cggttgagga taaccttggc t
//
LOCUS       DAVFJR010000063         8455 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVFJR010000063 DAVFJR010000000
VERSION     DAVFJR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.064"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..5693)
                     /locus_tag="VU722_002039"
     CDS             complement(<1..5693)
                     /locus_tag="VU722_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017271.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1772934.1"
                     /translation="MKKSYRDDNGEKVFRYSIRKYHFGAASVAVAALMFFANGAVAAS
                     ETITPTTASDIVKVDSDSNADGDPGTSDEEDSSKVSTRQPLELKSVDELKGQEAPVEE
                     NNQVQAAAESETTGVESNSAQPETNPASQEAPQAEGEGKQDQSTHVSNQTSSTSLLQP
                     RTLKNKQSDYDSIPLGDDEDDEDDVRNGLFSSENPVTTIQPRSPRSVTSRSVPPKTTG
                     SSPYNDKYRYYFERGQDPENSQLPRYTYAFFNEKVIFGLEEATKVSHIKDYLKEEIKP
                     TTDGFSWKVTVNQARQNLNGISFLFSVPNGQSLVPNSVTVTQVDDAGTTVKSSDPGDR
                     NDDHITASLKATNANAVMKGTPTRTNASGGDGFVGSTGHYDVSSIDRIWNEANLPDKD
                     SFHSRGQGNNNNARTGLQNDEERKLGDSKKMIINSSGGTVYSGKIAGNTSYTITFKTR
                     GSNDLDKLAYFSAVKGSNGGKTYLAMLLHARTQGERDFADKIRFRLKGNGYYQVEQNT
                     AYYTSTVLNSTGQEIKKDGANTAYSYSKYKDKPLDNGVKGVLTGNDTNDTDKAFDLDE
                     YSYSEYVDDQGQVLNKDDLSAQLEEQQQTITWYKGGQQISKSDLTKDAISSSGVHTYR
                     YRVSYKDNSFNEGEIHFVTKPKKPEITTDIETKLGQTLDVTVRNIEPNSEVTLYRKGA
                     NNQAGSLIGTVAANNQGNQVTFSGVNLQAGTYYVKQKAAGSWLDRSNRRVEGVYSDPS
                     SDKKVDGLRVGTTGKIIQYDTIDRKPINQQLVRDNPRNAALDHAFIAESPDGIKTVDV
                     QNPDNLPGFTTNEPSNASSPTRKGINVHVPAGNMQGTYRLVFEVVSNSGTRKTFTTII
                     NYPPVAPSFETTSEKLKGKAQETLKTAQPPIIINAKGVSVSNNKVQTGKKWKVFLVRG
                     GFNNNNNIVPKAEGYEIIAEALPRDGDKRAIFTPDKFKVDKLGTQPLRLITALVDEKT
                     GKVDENVVSTLSESSIQATNPITQYQIRPEVQQDPDTLEVTAKVGQGTANKAKVTYFH
                     QGLVPVSEIFTKVGNSWVKDSQNNNNITVSNNSDGTAIIHIPYGLNTKNTPIAASQHE
                     EGQSLWSENNSVIPKGDETAPKVSLGDAVLPTTENDATTPIYKVVQGSAFAPKLKVWD
                     NIGSVKELDITDIPAGITKQKFGTTFQSQDNAKEANKYSGSTFSGNVADTQAVGQYTA
                     QITVKDASNNTATYYLRYEVLPKVEARQAKFPQVKSKALQDGENPETYIQFKNNTQNV
                     SKPSVADVTWERQPSTATEGLDKTGVVKVTYHVTDENGVARDEVKTVTINTPVYHATV
                     NNGGVYTTTVGTNFSASTSATGGYVNSNFKPNVKYYWKSNRENNYPEYGGDTRSQTAD
                     YLGKRQDTIRVFYPNSQDVQDYQDKRSEDHVITFISKPRIPSVDAASLAGKANQENQT
                     VIVSNVTPGTTVKLYNGDTEIGSVNVPKGDNESYTTVKNNVTVTVNGTLPLSDNIRAK
                     TIYTPDNVDSGYSTSVSSTTQAPSKPSISQSPEDLVVKAKVGQDGATKVTLTYINANG
                     VAKTVGFTKNHGNWDKDNANADATVSITNETDGLGEIQLQQDTAQAGSEVTVKQKTDT
                     SDYSPSATIKALSRLEDLRNVAQADGAVDIHVPEDATRMSLTYTPTGQATPTTLEYTK
                     NGRTWTAHNGINTYSDERKISIPKGVVEDGTTVSVIASNDSKTTTNVKSKAKFEQPSE
                     ITNTIRQNGDVEVTLPTNAEEVTLSYKNKQNVMSTVTVSKSQGNTWTVGNLPDGVSFR
                     DGKVTFDYRKVNRDTPITISATRGTGEEKSQQRTKTISIPEHEVEVTKITKKAGESTT
                     NEELLAAIDVAKKKSAVLKKGTQYPTTVGNYDLEVMVTYADDSTEIVRVPYEVTAV"
     gene            complement(5923..6612)
                     /locus_tag="VU722_002040"
     CDS             complement(5923..6612)
                     /locus_tag="VU722_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473604.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1772935.1"
                     /translation="MKGCYAHVWKKHRDNGEKNYRYSICKYHFGAASVAVVALMFFAN
                     GAVAASETITPKTAGDVVKADSDSNADGNPESSDEGDSKKALTDQPAELKSADEPKGQ
                     EAPVEESDSVQAAAESKTTGVESNSAQPETNPAPQAEGEGKQDQSTPVANRTAAESIQ
                     STLEALLANLTLDSMKALHTEVEEGLAKAKTVLENPKATQAQVDEQVKLMEDLTRRVR
                     EACLLRFFFLK"
     gene            complement(6994..7457)
                     /gene="tnpA"
                     /locus_tag="VU722_002041"
                     /pseudo
     CDS             complement(6994..7457)
                     /gene="tnpA"
                     /locus_tag="VU722_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(7729..7938)
                     /locus_tag="VU722_002042"
     CDS             complement(7729..7938)
                     /locus_tag="VU722_002042"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772936.1"
                     /translation="MFSQLRMREEQALLAQDYALETARVEGIEQGLERGKLFAFLDMV
                     RQGLLTPEVASEQLCMTVAEFEEFL"
     gene            complement(7931..8047)
                     /locus_tag="VU722_002043"
     CDS             complement(7931..8047)
                     /locus_tag="VU722_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU1772937.1"
                     /translation="MVGVFRQQALYPATRASHQPSRPTAGLQELVRGGQENV"
     gene            complement(8093..8272)
                     /locus_tag="VU722_002044"
                     /pseudo
     CDS             complement(8093..8272)
                     /locus_tag="VU722_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248584.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
BASE COUNT         2102 a         1850 c         1510 g         2993 t
ORIGIN      
        1 actgccgtta cttcataagg caccctaact atctcggtac tgtcgtctgc ataagttacc
       61 ataacttcaa gatcataatt tcctacagtt gttggatatt gcgttccttt tttcaataca
      121 gccgattttt tcttagctac atcaatcgca gcaagtaatt cttcatttgt cgttgactcg
      181 cccgcttttt tcgtgatttt cgtcacttca acttcatgct ctggtataga gattgtcttc
      241 gttctctgtt gtgatttttc ctctcctgtt cctctagtag cggatattgt aataggagtg
      301 tctctattta cttttctata atcaaatgta accttaccat ccctgaagct tactccatct
      361 ggtaagtttc ctactgtcca agtattacct tggctcttag atactgttac tgtagacatt
      421 acattttgtt tatttttata gcttaatgta acttcttcag cgtttgttgg taatgtaacc
      481 tctacatctc cgttttgacg tatagtatta gttatttcac taggttgttc aaacttcgct
      541 ttacttttta cattagtagt tgttttacta tcgtttgatg caataaccga aactgtagta
      601 ccatcctcta caacaccttt tggaatggat attttacgtt catcagaata agtatttatt
      661 ccgttatgag ctgtccatgt tctaccgttt ttcgtgtatt ctaatgttgt cggcgtagcc
      721 tgccctgtcg gtgtataagt taaactcata cgagtcgcat cttccggaac atggatatcc
      781 acagccccat ctgcttgagc aacatttctt agatcttcta atctacttag cgcttttatt
      841 gttgctgaag ggctgtaatc tgatgtgtcc gttttttgtt taacagtcac ttcagaacct
      901 gcttgtgctg tatcttgttg aagttgaatt tcacctagac catcagtctc atttgtaatc
      961 gatactgtag catcagcatt cgcattatct ttatcccagt ttccatggtt tttcgtaaat
     1021 cctactgttt tagcaactcc atttgcatta atataggtaa gcgtcacttt tgtagctcca
     1081 tcttgcccta ctttcgcttt cactactaaa tcttctggac tttgagagat gcttggtttc
     1141 gatggtgcct gcgtcgtact gcttacactc gtgctatatc ccgagtctac attatcaggt
     1201 gtgtatatcg tttttgcacg aatattgtca gaaagtggta atgtaccatt taccgttacc
     1261 gtaacattat ttttgacagt tgtataagac tcattatcac ctttcggtac atttactgaa
     1321 ccaatctcag tatcgccatt gtataattta acagttgttc ctggtgtaac attacttact
     1381 attactgttt ggttttcctg attcgctttt ccagctagtg acgctgcatc gacagacgga
     1441 atacgcggtt tagaaataaa cgtaatcaca tggtcttctg aacgtttatc ttgataatcc
     1501 tgaacatctt gggaatttgg atagaaaact cgaattgtat cctgacgttt tcctagataa
     1561 tctgctgttt ggctacgtgt atctcctcca tattcaggat aattattctc tctgtttgat
     1621 ttccaataat atttaacatt aggtttaaag ttagaattta catatcctcc agttgcactg
     1681 gtagaagctg agaagttagt tcctactgtt gttgtataaa caccaccatt attcacagtt
     1741 gcgtgataga ctggcgtatt aattgtcaca gttttaactt catctcgggc tacaccgttt
     1801 tcatctgtca catggtaggt aacttttact actcctgttt tatcaagacc ttcagttgct
     1861 gtacttggtt gtctttccca agttacatct gctactgatg gtttgctgac attttgagta
     1921 ttatttttaa attgaatata agtttctgga ttttctccat cttgtaatgc tttactttta
     1981 acttgaggaa acttagcttg cctagcttct acttttggaa gaacctcata acgcaagtag
     2041 taagtagctg tattatttga tgcatctttt acagtaattt gagctgtata ttgtcctact
     2101 gcttgtgtat ctgcaacatt accactaaat gttgaaccac tatatttatt cgcttcctta
     2161 gcattatctt gactttggaa tgtagttccg aatttttgct tagtaattcc agcagggata
     2221 tctgttatat ccaactcctt gacactacct atattatccc aaaccttaag tttcggtgca
     2281 aatgcacttc cttgtacaac cttgtatatc ggagttgtag catcattttc agtagttgga
     2341 agaacagcat ctcctaaact caccttcggt gccgtttcat ctccttttgg gattacacta
     2401 ttattttctg accatagact ttgtccttct tcatgttgac tagctgcaat tggcgtgttt
     2461 tttgtattca acccgtatgg aatatggatt atcgctgttc catctgaatt attcgaaaca
     2521 gttatattgt tattgttttg tgaatctttg acccatgaat ttcctacttt agtgaatatt
     2581 tcgctaacag gaactaatcc ttgatggaaa taagtaactt tcgccttatt agccgtacct
     2641 tgtccaactt tggcagtaac ttctaaagta tctggatctt gctgtacttc cggtcttatt
     2701 tggtattgtg ttattggatt agttgcttgt atactactct cactcaaagt agaaactacg
     2761 ttttcatcta cttttcctgt cttttcatct accaatgcag ttataagtcg aagtggttga
     2821 gttcctaatt tatccacctt aaatttatca ggtgtgaata tggctctttt atctccatct
     2881 cttggtagtg cttcagcgat aatttcataa ccttctgctt taggaacaat attattatta
     2941 ttattgaatc cacctctaac caaaaagact ttccattttt tgccagtttg caccttatta
     3001 ttactaacac tcacaccttt tgcatttata atgataggcg gctgggctgt ttttagagtc
     3061 tcttgagctt tccctttcaa tttttctgat gttgtttcaa aagatggggc aactggtgga
     3121 tagttaataa tcgtggtaaa tgttttcctt gtaccactat tagatactac ttcaaataca
     3181 agtctataag taccctgcat atttcctgcc ggcacgtgta catttatccc ttttctagtg
     3241 gggctagatg cgttagacgg ttcgtttgta gtgaatccag gtaagttatc tggattctgc
     3301 acgtctacag ttttaattcc atctggagac tctgctataa aagcgtggtc taaagcagca
     3361 tttcttgggt tgtctcttac taactgttgg tttattggtt ttctatcgat tgtatcatat
     3421 tgaataattt taccagtagt tcccactctt agtccatcta cttttttatc agaagaggga
     3481 tcagaataaa ctccttcaac ccttctattt gaacggtcta accagcttcc tgccgctttt
     3541 tgtttcacat agtaagtccc ggcttgaaga ttgactcctg agaatgtaac ttgatttcct
     3601 tgattgttag ctgcaactgt acctataagt gaaccagctt gattatttgc accttttcta
     3661 tataatgtca cctcactatt tggttcgata tttctcactg taacatcaag tgtttgccct
     3721 aattttgttt ctatatctgt tgttatttca ggctttttag gttttgttac aaaatggatt
     3781 tctccttcat taaaagaatt gtccttatag gaaacgcgat acctgtaggt atgaacccca
     3841 gagctagaaa tagcatcttt tgtcaaatca gatttactga tttgttgacc acccttatac
     3901 caggtaatcg tttgctgctg ttcttctagc tgcgctgaca aatcatcttt gtttaaaact
     3961 tgaccttggt catcaacgta ctcactataa gaatattcat ccaagtcaaa agctttatct
     4021 gtatcatttg tatcattgcc ggtcaatact cctttgactc cattatcaag aggtttatcc
     4081 ttatatttag agtatgagta agctgtattg gcaccgtctt tcttaatttc ctgaccagtg
     4141 ctattcaata ccgtgctggt gtaataggct gtgttttgct ccacttgata gtaaccattg
     4201 cccttgaggc ggaagcgaat cttatcagca aaatcgcgtt caccttgcgt tctagcatgc
     4261 agcaacatag ctagataggt cttaccccca ttactacctt ttacagcaga aaagtaagcc
     4321 aacttgtcca ggtcatttga ccctctagtc ttaaaggtga ttgtatagct ggtatttcca
     4381 gcaatttttc cagagtagac tgttcctcct gaggaattaa taatcatttt tttagagtct
     4441 ccaagcttac gttcttcatc gttctgtaaa cctgtcctag cattgttatt atttccctgc
     4501 cctcgagagt ggaaggagtc tttgtctgga agatttgcct cattccaaat tctatcaatt
     4561 gaagaaacgt cataatgccc agttgatcca acaaatccgt ctccaccact tgcatttgtt
     4621 ctggtaggag tccctttcat tactgcatta gcattagtag ctttcaaaga agctgtaatg
     4681 tgatcatcgt ttctatcccc aggatccgaa cttttaactg tagtccctgc atcatctacc
     4741 tgtgtcacag tgacgctatt tggaacaaga ctttgtccat taggcacgga aaagagaaag
     4801 ctgattccat ttaagttttg tctcgcttgg tttacagtaa ctttccagct aaatccatct
     4861 gtagtcggtt taatttcttc ctttaaataa tccttaatgt gggaaacctt agtcgcctct
     4921 tcaagaccga atatgacttt ttcattaaag aaagcgtagg tatagcgtgg aagttggctg
     4981 ttttctggat cctgtccacg ttcgaaatag tagcgatact tatcgttata agggctagaa
     5041 ccagttgttt tcggcggaac tgagcgactg gttacagagc gagggctccg tggttggata
     5101 gtggttactg gattttccga agaaaacagc ccatttctta cgtcatcctc atcatcctca
     5161 tcatcgccaa gtggaataga gtcatagtca gactgcttgt ttttgagcgt ccgcggctgg
     5221 aggaggctgg tgctgcttgt ttggttggaa acatgagtcg actggtcttg ttttccttct
     5281 ccctctgctt gaggagcttc ttgactagct ggatttgtct ctggctgagc agagttggat
     5341 tctactccag tcgtttcaga ctcagcggct gcttgtactt gattattttc ctcaactggc
     5401 gcttcttgcc ctttcaactc gtcgaccgat ttgagttcaa gtggctggcg agttgaaacc
     5461 ttgctcgagt cttcctcatc cgaggttcct ggatccccat ctgcgttgct atcagagtct
     5521 accttaacga tatcacttgc cgtagttgga gtaatcgttt cactcgctgc cacagctcca
     5581 ttggcaaaaa acatcagagc cgctaccgca acactggcag caccaaagtg gtacttacga
     5641 atggaataac ggaagacctt ttccccgtta tcatcacgat atgatttttt catgattgaa
     5701 ttacctctcg ttttttcctt tctggaggca ctaaaaaata ccccccctta aatattttag
     5761 tatttaagga aaagatatgt ttttttcttt ttgttcccta gcttgtcaaa agacaagttt
     5821 tgagacagta ttattatata ctatttttac aaatttgaac agcaaaacgc taactttttt
     5881 cagccgtctt gtcacttatt tttataggtg gtttttgagc tgctatttca gaaaaaaaaa
     5941 acgaagcaag caagcttccc tgacccggcg agtcaggtct tccatgagtt tgacttgctc
     6001 atcaacctgt gcttgcgtcg cttttggatt ctctaagacc gtcttagcct ttgcgagacc
     6061 ttcttccact tcagtgtgaa gagccttcat ggagtctaag gtcagatttg ccaacaaagc
     6121 ttctagggtg ctttgtatcg attcggctgc tgtcctgttg gcaacaggag tcgactggtc
     6181 ttgttttcct tctccctctg cttgaggagc cggatttgtc tctggctgag cagagttaga
     6241 ttctactcca gtcgttttag actcagcagc tgcttgtact gaatcgcttt cctcaactgg
     6301 cgcttcttgc cctttcggct cgtcggctga tttgagttca gctggctggt cagtcagagc
     6361 tttcttggag tctccctcat ccgaggactc tggatttcca tctgcgttgc tatcagagtc
     6421 agccttaacg acatcacctg ccgtttttgg agtaattgtc tcactcgccg ccacagcccc
     6481 attcgcaaaa aacatcaagg ccacaacagc aacgctggca gcaccaaagt ggtacttaca
     6541 aatggaataa cggtaatttt tttcaccatt atccctatgt tttttccaaa catgagcata
     6601 gcatcctttc attgtatcac aggtcaactt tcctcaaaag agtacacaaa aacccgtaac
     6661 agataatatg tcaactttat agtaatactt ttctagaaag aaatcaagta taaagctaga
     6721 tgaagataag attagcataa gattaaaaat gcagcaaaaa caccgatata acaacatttt
     6781 tctgtaatta tatatatatg cacaccttta tataacaatc ttattatgga taatatttta
     6841 aatttaatat aaatcatgac cacccgtcta acgggtggtt tgtaccaggg ctataagccc
     6901 aattaccagc cagcgcctaa agacgctggc tttcactttg ttcaatcctt attgctcttg
     6961 actcgtcact tgcctcttaa agaggctttg gtattactta ccactatccc taaagggatc
     7021 ctcatattct tttacattca atttatctag tgctatatca tgcttttcct gttctggtat
     7081 atatttctta attgtagctt cattgactcc caccgtactc acataataac cttccgccca
     7141 gaaatgccga tttccaaatt tgtacttgag attggcgtgt ttgtcaaaca tcatgagtgc
     7201 actttttcct tttaaataac ccatgaaact cgaaacactt atactaggtg taatacttac
     7261 taacatatgt acatggtctg gcattaagtg accctcgata atttcaactc ctttataact
     7321 acacaagcga tgaaatattt cgcctaaact acttcgatat tgattataga taacttttcg
     7381 tctatactta ggggtgaaca caatgtgata gaacagtgcc actttgtgtg cgataaacta
     7441 tgagcctttt gtgccatgtt tttctccttt cgctttacaa ttggcttgaa cacctttatt
     7501 gtatcgcgtt tggagttttt tgggtataac cttcgacgcg cacctaacgg agcgagacgg
     7561 actaatagtc acataataaa aaacagattc tatctataga aagataaaat ctgccatttt
     7621 ttctatataa aatcagcaaa tccattctgc tgaaaatcgt gaaatatgat gtgaatttcc
     7681 gaccactctg acaggatttt gagggaaaag ctagatatat tccctaactt acaaaaactc
     7741 ctcaaactca gcgacagtca tacacaattg ctcactcgca acctcaggtg tcagaagacc
     7801 ttggcgaacc atatctaaga aggcaaaaag ttttccacgt tctaaacctt gttcaatacc
     7861 ttcgactcta gctgtttcca aggcatagtc ctgtgctaat aaggcttgtt cttctcgcat
     7921 acgtagttga ctaaacattt tcctgtcctc ctcggaccag ctcttgtaat ccagcagttg
     7981 gtctgcttgg ctgatggctc gctcgggttg ctgggtaaag ggcttgttgc cgaaaaactc
     8041 caaccacggt ttgcgaacct cgtctttgct ggtttctctg tatttttagg tcttatttat
     8101 gatgtttttt caatagtgtc tcaaactcag ctacggtcat gcccaattgt tcactcgcaa
     8161 cctcagatgt cagaagacct tggcgaacca tatccagaaa ggcaaaaagt tttccacgtt
     8221 caagtccttg ttctaaacct ttttcgatac cttgttcaat cccttcagct cgtccacgtt
     8281 caagtccttc tgcacgacct ctctccaacc ctttttcctc agcttgttcc aaggcatagt
     8341 catgagccaa taatgcctgt tcttctcgca tacgtagttg actaaacatt tttctgtcct
     8401 cctcggacca gctcttgtag tccagcagtt ggtctgcttg gctgatggct cgctc
//
LOCUS       DAVFJR010000064         8447 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVFJR010000064 DAVFJR010000000
VERSION     DAVFJR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.065"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            244..>8447
                     /locus_tag="VU722_002045"
     CDS             244..>8447
                     /locus_tag="VU722_002045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU1772938.1"
                     /translation="MKKSYRDDNGEKVFRYSIRKYHFGAASVAVAALMFFANGAVAAS
                     ETITPTTASDIVKVDSDSNADGDPGTSDEGEPKQALTDKPAELKAADEVKTQEAPAEG
                     ANQEQAGDESETTGVESNSAQPETNPASQEAPQAEGEGKQDQSTPVSDQTSSTSLLQP
                     RVLKSKQSDYDSIPLGDDEDDEDDVRDGLFSSENPVTTIQPRSSRSVQPKENSSGVHS
                     VRAEAKQSRFGQVKGKPLIHGDNPANYIKFKNANGQEVQKPAGVDVAWAEKPSTTQEG
                     LNKTGRIKITYHLTNENGMEVNREEFVTISTPVYHATLTQNRYVTTYGGEFTNRINPT
                     DGRRYINYNAKSHFQLNNLRAYWEHSSGSNGSTYSSVIRDWNTRYLGKKREKLMVRYP
                     SDDGIYRSNRDDGGGRYEILDGTFIVKPVKPSIQTSLGKVGKNTLTVNNVNSGTTVVA
                     YDMANPRIPREIGRVSVPKDGDYRIKNGIELTLNSGEVLRKDQKIATKVIYEITNADQ
                     RTESDSSDTLTVKESLVANGIHVIKDETYTGNVKDRIRYNDDTDADRRTAFPNNASAS
                     WVQNPDYSRLGTRNYSANVRIPGQGDARVDVPVHVYAPASLKASSYNNKQGTLSNGTE
                     AENYIQFRDGNATIDKPNNVTVRWKDGQAPDVSRPGTQQKTIEVVYPGNDGPSSTVIR
                     EYQVTFTSYHAQAQKREYTRTIGENFTSTTAKSYVKKADGSPELPQETEYAWKKDETA
                     NREYGSETWGKVNDDWLGKKTNKIKVYYPNADGGNNKADNLAEETEEITFITKPAKPR
                     IASNLTGQAGTRSNVVIQNATPGTTLELRDGDTVLGKVEVPKNNSLYSQLTTATITPT
                     ADIPASANITVKSIYSPNNQDQRVESDSSDAVASTQITVSAKGTIQTLAGTGHIAGLS
                     NLNKATLSTLLNLSDGSAVADGTTGRWESGQNIAKGQAGTRTEKLFVRLPGHTKEQEV
                     TFTVKTLAVPSAKAVVKDKGQDIVADDLSNYVTVEGQTGLSWKGNPSKVEVGKTLPKI
                     KVTYPRAGQNGIAVTDIQDQEVDAKVYSLEVNGVAKTRVTVGETFDPVAADYVTQVAN
                     TETLPSGVSYAWKNGNKPSSARVGKETYTVETSFGIGNDVPAELRGQKVETQVEVTVL
                     STKPSQPELGQNRNDLAITAVVGKENANKAVITFRDDADQEQTVTFEKGANNQWDKVG
                     GINQPTVQILNNNDGTAIVHLTAGTAKVGSSVSIKQQKADSDYSEAATLVAKERLDGV
                     SATSKDDGSVDVVVPSEAKKASVTYTPEGQSQAKTVELAKAQDGTWSAPANSGLLVNK
                     DNTTGILTITVPASQVVDGSKVVGNADSDSKLSIDAEARAKAPQPVEFDSSIRHNGDI
                     VLTLPNNADTATINYPVSDTELKTATATKGQDGSWRLSPDSGLELASTNGVTKITLAY
                     TKLSGNRTVTASAKAGSGEGESKERTFTKTVPAHTTPTTQNVVIAANATPTDDQLLTG
                     VIANNKQSVAAKQTQTAIAAGTTKEIPATLTYTDGSTEEITITVQSKPTAPTVNGLES
                     RARVAVPGLLSTARTITGQAMQGAEKVKLTLQNGSEKEVDVAADGSWSYTLAADEFLT
                     QTISNSNAKYSSTKIRLVQVKDGLESEPKDIDILMGRATIDTPLRAGRDITLHIPHDT
                     TSGYIRIGGSVERGGVDIGLKKVNGVWTLDTDANRASKLELVSETDPTNPALTKVTLK
                     VKATDNASYSPPFTIGGDSGNVKFRAHYYSGRDIGAVVPMGRQGQFEWILSGQPTNTR
                     PTVGWETGKEIQDGQKIPSPTVDELKDFFKGEDAEDDAGLTVGYSASNRGKLRVRLYT
                     SGTNQTVRTNVRGRIDPGNYRLLLSTIDAAGVESNILERNVIIQSYADYYRDAVQYPT
                     TAQKVTYSDTDITNGNFTAAAKTGNFTAAAKTRFKDKIETINRQNTQLPTSVTYSVGT
                     TDDKAKVAVINFPDGSTIDISHSQVAKPDVPTITPTDTEQQGMPKVTDADREISGTAL
                     QNATKVTLKLQTGKGIEIVKEITVNNTKDFAALVPGEGLLKNGVWKYKLADGQYLRQT
                     DATAEPGSSSLPLKATQTVFDAVSDDTSIYVANKRTVEGKKIEGEVGSPDLKKYIDKP
                     QDAVVYKEKGQEKPFPSDFIAKWENTPNFDTVGTFTYKVKFYEKDGNTPADHISEGVE
                     VTFVVKSKAPAILDYTNRDNGETLVNIPQDADEVVFSILRSDTAVDTITVKKSEGWTA
                     TGIQKRDNTWVFPANSVHGNRTVTAVATAGKGDTKSVEMLTLITTLAHDVTVNEITKP
                     TKGNPTSQDLLDAVEVTNKKSVALKQGENYPETFGTHQIHLIVTYQDDSTEEKVANYT
                     VPDTRDAAKDDIDTKATAKKNDIEADDKLTTEEKQAAKDKVDAAAQSAKDAVTAATTN
                     DGVTQAQNDGTTAVNNVDTTPKAKPSAKAEIDAKVQDANNAIDQNQDLTDDERREAKK
                     AVKDAADEAKANIDKATSAGELTTAKNNGLDKLNEPQDASVKQKAKDDIDTKATAKKN
                     DIEADDKLTTEEKQAAKDKVDAAAQSGTNPVTPPSTTRSRRTPPRRSRRSVGFVGNSQ
                     TGTTPSAVDKSELQSLVEDLERRLQDLADLSPEALEEAQSILREAQVALANDSLTAQE
                     LTELLAKVRQALNSIQAGTSADKSPSTSNSNKEAESAKEPTNATDVPLYGVFGAAVLS
                     LLGALLFAVARKKNSQLDKLSR"
BASE COUNT         2881 a         1668 c         1957 g         1941 t
ORIGIN      
        1 aaaatgacaa gtattttgat aataacttgc caacatctat cacttatcgg aatgttaaaa
       61 aagttagcgt tttgctgttc aaatttgtaa aaatagtata taataatact gtctcaaaac
      121 ttgtcttttg acaagctagg gaacaaaaag aaaaaaacat atcttttcct taaatactaa
      181 aatatttaag ggggggtatt ttttagtgcc tccagaaagg aaaaaacgag aggtaattca
      241 atcatgaaaa aatcatatcg tgatgataac ggggaaaagg tcttccgtta ttccattcgt
      301 aagtaccact ttggtgctgc cagtgttgcg gtagcggctc tgatgttttt tgccaatgga
      361 gctgtggcag cgagtgaaac gattactcca actacggcaa gtgatatcgt taaggtagac
      421 tctgatagca acgcagatgg ggatccagga acctcggatg agggagagcc caagcaagct
      481 ctgactgaca agccagctga actcaaagca gctgatgagg tgaaaacgca agaagcgcca
      541 gccgagggag ccaatcaaga gcaagcagga gatgagtctg aaacgactgg agtagaatcc
      601 aactctgctc agccagagac aaatccagct agtcaagagg ctcctcaagc agagggagaa
      661 ggaaaacaag accagtcgac tcctgtttcc gaccaaacaa gcagcaccag cctcctccag
      721 ccgcgggtgc ttaagagcaa gcagtctgac tatgactcta ttccacttgg cgatgatgag
      781 gatgatgagg atgatgtaag agatgggctg ttttcttcgg aaaatccagt aaccactatc
      841 caaccacgga gctctcgctc agttcagcct aaagaaaata gttctggagt ccattcagta
      901 agagcagaag ccaagcaaag tcgattcgga caggtcaaag gtaaaccctt gatacatggc
      961 gataatccag ctaactatat caagtttaaa aacgctaatg gacaagaggt tcaaaaacca
     1021 gctggagtag atgttgcttg ggcggaaaaa ccaagtacta cacaggaagg acttaataaa
     1081 acaggtcgta tcaaaatcac ctaccaccta acgaatgaaa atggtatgga ggtaaatcga
     1141 gaagaatttg taactattag cacccctgtc tatcatgcga ctttaacaca gaaccgctat
     1201 gtaacaacct acggtgggga gtttaccaat cgtataaatc ctacggatgg tagacgctat
     1261 attaactata atgcaaagtc tcattttcaa ctaaataact tgcgtgctta ctgggaacat
     1321 tcttctggtt caaatggctc aacctattcc tctgttattc gagattggaa tactcgttat
     1381 ttaggtaaga aacgtgagaa attgatggtt cgctatccaa gtgatgatgg catctatcgt
     1441 agtaatagag acgacggcgg tggacgatat gaaatactag atggaacttt catcgttaag
     1501 ccagtcaaac caagcattca aaccagtctt ggcaaggtag gaaaaaatac cctgactgtc
     1561 aataatgtca atagtggaac aacagttgtt gcttacgaca tggcaaatcc taggattcct
     1621 cgtgaaattg gacgtgtatc agttccaaaa gacggggatt acaggattaa aaatgggatt
     1681 gagcttacgc ttaactctgg tgaggtctta cgaaaagatc aaaaaattgc gactaaagtt
     1741 atctatgaga ttacaaacgc tgaccaacgc acagagtcag atagtagtga taccctgacc
     1801 gtcaaggaaa gtttggtagc taatggaatt catgtcatca aggatgaaac ttacacaggc
     1861 aatgtcaaag accgcattcg ttacaatgac gatacggacg ctgatcgccg cacagcgttc
     1921 cctaataatg caagtgcgag ctgggtacaa aatccagact atagtagatt aggtacacgt
     1981 aactacagtg ccaatgtaag gattccaggt caaggagacg ctagggttga tgtaccagtt
     2041 catgtctatg cgccagcgag tctgaaagca agctcttaca ataacaaaca aggtactcta
     2101 tctaatggta cagaagcaga aaactatatc caatttagag atggcaatgc aacgattgat
     2161 aaaccaaata atgtcactgt gcgttggaaa gatggacaag ctccagatgt ttcacgacca
     2221 ggaactcaac aaaaaacaat agaagttgtt tacccaggca atgacggacc tagctcaaca
     2281 gtcatcagag agtatcaagt gacgtttact agctatcatg cacaagctca gaaaagggaa
     2341 tatactcgta caattgggga aaactttacc tcaaccacag ctaagagcta tgtcaaaaag
     2401 gcagatggtt cgcctgagtt gccgcaagaa acagagtacg cttggaagaa ggatgagaca
     2461 gctaatagag agtatggttc ggaaacatgg ggcaaggtga atgatgactg gctcggtaag
     2521 aagaccaata agattaaagt ttactatcca aatgcggatg gaggcaataa caaggcagat
     2581 aatctagctg aagaaaccga agaaattacc tttattacga aaccagctaa accaagaatt
     2641 gcaagcaatt tgacaggtca agcaggcaca cgttcaaacg tagtgattca gaatgcgaca
     2701 ccaggaacaa cgcttgaatt gcgtgatggt gatactgttt taggtaaggt tgaagttccg
     2761 aaaaacaata gtttatacag tcaattgaca accgcaacta ttacgcctac ggctgatatc
     2821 cctgcttcag cgaatatcac tgtcaagtct atctattcac caaataatca ggatcaacgt
     2881 gtggagtctg acagtagcga tgcagtagca agtacccaga ttactgtgtc tgcaaaagga
     2941 accattcaaa ccttggcagg aacgggtcat attgctggtt tgagcaacct caataaggca
     3001 acgctttcta ccttactcaa tctttcagac ggaagtgcgg tcgctgatgg cacaacagga
     3061 cgttgggaat ctggtcaaaa cattgccaaa ggtcaggcag gcacacgaac tgaaaaactc
     3121 tttgttcgct tgcctggtca tacaaaagag caagaagtaa cttttacagt caagacgcta
     3181 gctgttccga gcgctaaagc agttgtgaaa gacaaaggac aagatatcgt tgcagacgac
     3241 ttgagcaact atgttacagt agaaggacaa actggactca gttggaaagg aaatccaagt
     3301 aaagtagagg ttgggaaaac tcttccaaaa atcaaggtaa cctatccaag agctggtcaa
     3361 aacgggatag ccgtgacaga tattcaggat caagaggtag atgctaaggt atacagccta
     3421 gaagttaatg gtgttgccaa gacaagagta actgtaggtg aaacatttga tccagttgct
     3481 gctgactacg tcacacaggt agccaataca gaaactcttc catcaggtgt tagctatgca
     3541 tggaagaatg gcaataagcc aagttcggct agagtaggga aagagaccta cacggtagag
     3601 acaagcttcg gtataggaaa tgatgtccct gcagaacttc gtggtcaaaa agttgaaacg
     3661 caggtcgaag tgacagtcct ttctactaaa ccaagtcagc cagaacttgg tcaaaaccgt
     3721 aatgatttag caatcacagc ggttgtcgga aaagaaaatg ccaataaggc agtaatcacg
     3781 tttagagatg atgctgatca ggaacagact gtgacctttg aaaaaggggc taacaatcaa
     3841 tgggataagg ttggaggaat taatcaaccg acagttcaaa ttctaaataa taatgatgga
     3901 acagctatag ttcacttgac agcaggtaca gctaaagtcg gtagttctgt aagcatcaaa
     3961 cagcaaaaag cagattcgga ctacagtgaa gctgcaactt tagtagctaa agaacgtttg
     4021 gatggtgtca gcgcgacaag taaagacgat ggttcggtag atgtcgttgt accaagtgaa
     4081 gccaagaagg cttctgtgac gtatactcca gaaggtcaaa gtcaagcgaa gacagttgag
     4141 ttagccaagg ctcaagacgg cacatggtca gcgccggcga attcaggtct tctagttaat
     4201 aaagacaaca caacaggcat tctgaccatt acggttccag caagccaagt agtagacggt
     4261 agtaaggttg taggaaatgc agatagcgat agcaagttga gtatagatgc agaagcgaga
     4321 gcgaaagcac cgcaacctgt cgaatttgat agctctattc gtcataatgg agatatagtg
     4381 ttgacgctcc caaataatgc ggatacagca actatcaact atccagtgag tgatacagag
     4441 ctgaaaactg ctactgcaac taaggggcaa gacggtagct ggaggctttc acctgactca
     4501 ggtcttgagc ttgctagcac aaatggagtc actaagataa cgctagcata tacaaaattg
     4561 agtggcaatc gtacagtgac tgcaagtgct aaagcaggaa gtggtgaggg agagagtaaa
     4621 gagcgtacct ttactaaaac agttccagca cacacaactc cgacaaccca aaacgttgtc
     4681 atcgctgcaa atgcgacacc aactgatgac caattattga caggtgtaat agctaacaat
     4741 aaacaatccg tcgcagctaa acaaacacaa actgctattg ctgcaggaac tacaaaagaa
     4801 attccagcaa ctttgaccta cacggatggt tcgactgaag aaatcactat aacggttcag
     4861 tctaagccga cagcaccgac ggtgaatggt ttagaaagtc gtgcaagggt tgccgtaccg
     4921 ggtcttttat caactgctcg cacgattaca ggtcaggcta tgcagggtgc agaaaaagtt
     4981 aaattaactt tacaaaatgg tagtgagaaa gaagtagatg tggctgccga tggtagttgg
     5041 tcttatacgc ttgcagcaga tgaattcctg actcaaacaa tatcaaatag taatgctaaa
     5101 tatagttcta cgaaaatccg tcttgtgcaa gtgaaagatg gtctagaatc tgaaccaaaa
     5161 gacattgaca ttttgatggg gcgcgccact attgatacgc cacttcgagc tggacgtgat
     5221 atcacccttc acattccgca tgacaccact tctggctata tccgcatagg aggttcggta
     5281 gaacgaggtg gagtagatat cggactcaag aaggtgaacg gtgtctggac tcttgataca
     5341 gatgccaata gggcaagtaa gttagaactt gtgagtgaga cagacccgac gaatccagct
     5401 ttgaccaagg ttacgctcaa agttaaagcc acggataatg cctcgtacag tccaccgttt
     5461 accattggag gtgacagtgg aaacgtgaaa ttcagagctc actattacag tggtagagat
     5521 atcggtgcag tagttccgat ggggagacaa ggtcaatttg aatggatttt gtctggtcaa
     5581 ccaaccaata ctagacctac agttggctgg gaaactggta aagaaatcca agatggtcaa
     5641 aagattccat cacctacagt agatgagttg aaagacttct ttaaagggga ggatgctgaa
     5701 gatgatgcag gtctcactgt aggatactca gcctctaata gaggtaaatt acgtgttcgt
     5761 ttatatacaa gtggaacgaa ccaaactgtt agaacaaatg tccgaggacg aatcgatcca
     5821 ggtaattata gactgctctt gtctactatt gatgctgcag gggtggagtc taatatcctt
     5881 gaaagaaatg tcatcattca aagttatgca gattactatc gtgacgctgt tcagtatcca
     5941 actactgctc aaaaggtaac ctacagtgat acagatatca ctaatggtaa cttcacagca
     6001 gcagccaaaa ctggtaactt cacagcagca gccaaaacac gttttaagga taaaatagag
     6061 actatcaatc gccaaaatac ccaacttcca actagtgtga cttatagcgt aggaactacg
     6121 gatgataagg cgaaagtagc tgtgattaac ttcccggatg gttctactat tgatatttct
     6181 cattcgcagg tagccaaacc agatgtaccg acaatcactc cgacggatac agaacaacag
     6241 gggatgccga aggtaactga tgctgataga gaaatttctg gtactgccct tcaaaatgcg
     6301 acaaaagtga cattgaagtt gcaaactggt aaagggatag agattgtaaa agaaattaca
     6361 gttaataata caaaagattt cgctgcctta gtaccaggag aagggctctt aaaaaatgga
     6421 gtatggaagt ataagctggc tgacgggcaa tacttacgtc aaacagatgc gacagcagaa
     6481 ccaggctcgt cctcactccc attaaaagca acacaaactg tatttgatgc agttagtgat
     6541 gatacgagta tctatgttgc caataaacgt actgtagaag gtaaaaaaat tgagggagaa
     6601 gttggcagtc ctgacttgaa aaaatacata gataaaccgc aagatgccgt tgtctataaa
     6661 gaaaaagggc aagaaaagcc attcccaagt gactttattg ccaaatggga aaatactcct
     6721 aactttgata ccgttggaac ctttacctat aaagtaaaat tttatgaaaa agacggcaat
     6781 acaccggctg atcacattag tgaaggtgtt gaagttacct ttgtagtcaa atcaaaagca
     6841 ccagcaatct tagactacac taatagagat aacggtgaaa ctcttgtgaa tattccgcaa
     6901 gatgctgatg aagttgtttt cagtatcctt agaagtgata cagctgtaga tactataact
     6961 gtaaaaaaat ctgaaggttg gacggcaaca gggattcaaa aacgtgataa cacttgggta
     7021 tttccagcta actcagtaca tggcaaccga acagtaacag cagttgcgac agcagggaag
     7081 ggtgatacca agagtgtaga gatgctgaca ttgattacaa cacttgctca tgatgttact
     7141 gttaatgaaa ttactaaacc tactaaagga aatccaacat cccaagattt gcttgatgca
     7201 gtagaagtaa ctaataagaa atccgtagca ctgaaacaag gagaaaatta tccagaaact
     7261 tttggaactc atcaaatcca cttgattgta acctatcaag atgatagtac agaagagaag
     7321 gtagctaatt atacagttcc agatacaaga gatgcagcta aagatgacat tgatacgaaa
     7381 gctacggcta agaaaaatga catcgaagca gacgacaagt tgacgactga agagaagcaa
     7441 gcagctaagg ataaggtaga tgcggcagct caaagtgcta aagatgcggt tactgccgca
     7501 actaccaacg atggtgtgac tcaagctcag aatgatggaa ctactgctgt taacaatgtt
     7561 gatacaacgc caaaagcgaa accatcagcc aaggcagaaa ttgatgccaa ggttcaagat
     7621 gccaacaatg ccattgacca gaatcaagat ctgacggacg atgagcgtag agaggctaag
     7681 aaagcagtga aggacgcagc tgatgaagct aaggctaata ttgacaaggc gacatctgca
     7741 ggagagctca caactgctaa gaacaacggt cttgataagt tgaatgagcc acaagacgca
     7801 agcgttaaac aaaaagctaa agatgacatt gatacgaaag ctacggctaa gaaaaatgac
     7861 atcgaagcag acgacaagtt gacgactgaa gagaagcaag cagctaagga taaggtagat
     7921 gcggcagctc agtctggaac aaatcccgtg actccaccat ctactacaag aagtcgcaga
     7981 actcctccgc gccgctctcg tagaagtgta ggatttgtag ggaattccca aacaggtaca
     8041 actccatcgg ctgtggacaa gtcagagctt cagtctctgg tagaggacct ggagcgtcgc
     8101 ctacaagatt tagcagattt atctcctgaa gcacttgagg aagcacagag tatcttgaga
     8161 gaggcgcaag tggctcttgc taatgactcc ttaacagctc aagaattaac ggaactcctt
     8221 gccaaagtta gacaggctct taattctata caagctggca catcagctga taagagtccg
     8281 tctacgtcaa actcaaataa ggaagcagaa agcgccaagg aacctacaaa tgcgacagat
     8341 gtccctctat atggtgtctt tggagctgca gtactctctc ttctaggagc tctcctcttt
     8401 gcagtggctc gtaagaaaaa ctctcaacta gataagcttt caagaga
//
LOCUS       DAVFJR010000065         8002 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVFJR010000065 DAVFJR010000000
VERSION     DAVFJR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.066"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            52..1752
                     /gene="dnaG"
                     /locus_tag="VU722_002046"
                     /pseudo
     CDS             52..1752
                     /gene="dnaG"
                     /locus_tag="VU722_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014178.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            1830..2939
                     /gene="rpoD"
                     /locus_tag="VU722_002047"
     CDS             1830..2939
                     /gene="rpoD"
                     /locus_tag="VU722_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU1772939.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVVPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            2953..3282
                     /locus_tag="VU722_002048"
     CDS             2953..3282
                     /locus_tag="VU722_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU1772940.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            3397..4440
                     /gene="cpoA"
                     /locus_tag="VU722_002049"
     CDS             3397..4440
                     /gene="cpoA"
                     /locus_tag="VU722_002049"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU1772941.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGISREKVSYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPVALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            4456..5781
                     /locus_tag="VU722_002050"
     CDS             4456..5781
                     /locus_tag="VU722_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU1772942.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            5810..5986
                     /locus_tag="VU722_002051"
     CDS             5810..5986
                     /locus_tag="VU722_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU1772943.1"
                     /translation="MRSGRDKKIAGVCAGVAHYFDMDPTIVRVIWGVLAFGYGAGVIA
                     YIILWIIAPVVTDY"
     gene            6045..6179
                     /locus_tag="VU722_002052"
     CDS             6045..6179
                     /locus_tag="VU722_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU1772944.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            6243..7553
                     /gene="obgE"
                     /locus_tag="VU722_002053"
     CDS             6243..7553
                     /gene="obgE"
                     /locus_tag="VU722_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU1772945.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            7563..7721
                     /locus_tag="VU722_002054"
     CDS             7563..7721
                     /locus_tag="VU722_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772946.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(7772..>8002)
                     /locus_tag="VU722_002055"
     CDS             complement(7772..>8002)
                     /locus_tag="VU722_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772947.1"
                     /translation="HPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         2402 a         1410 c         1883 g         2307 t
ORIGIN      
        1 tttacttttt ttctgaaata aagtatacta tataaagtaa actatgataa catggaggta
       61 ttgtgtatgg ttgacaaaca agtcattgaa gaaatcaaaa acaatgccaa cattgtggaa
      121 gtcataggag atgtgatttc tttacaaaag gcaggacgga actatctagg gctctgtcct
      181 tttcatggtg aaaaaacacc ttctttcaac gttgtagagg acaagcagtt ttaccactgt
      241 tttggttgtg gtcgctctgg tgatgtcttt aagttcatcg aggagtacca aggggttccc
      301 tttatggaag ccgtccaaat cttaggtcag cgtgttggaa ttgaggttga aaaaccgctt
      361 tatagtgaac agaagtcagc ttcgcctcac caagctcttt atgatatgca cgaagatgca
      421 gccaaatttt attacgctat tctcatgaca acgactatgg gagaagaggc gagaaattac
      481 ctttatcagc gtggtttgac agatgaagtg ctgaaacatt ttcggattgg tttggcacca
      541 ccagaacgaa actatctcta tcaacgtttg tctggtcagt accgtgaaga agatttcttg
      601 gattcaggcc tgttttacct ctcggatgcc aatcaatttg tagacacctt tcataatcgc
      661 attatgtttc ccctgacaaa tgatcaggga aaggtcattg ccttctcagg tcgtatctgg
      721 cagaaaacgg attcacaaac ttctaagtat aaaaatagcc gatcgactgc aatttttaac
      781 aaaagttacg aattatatca tatggatagg gcaaaaaaat cttctggtaa aaccagtgag
      841 atttacctca tggaaggatt catggatgtc attgcagcct atcgggctgg aatcgaaaat
      901 gctgtggcat ctatgggaac ggccttgagt cgtgagcatg ttgagcatct gaaaaggtta
      961 accaagaagt tggttcttgt ttacgatggc gataaggctg ggcaagccgc gactttgaaa
     1021 gcgctggacg aaattggtga tatacctgtg caaattgtca gcatgcctga taacttggat
     1081 ccagatgagt atctacaaaa aaatggacca gaagacttgg cctatctatt aacgaaaact
     1141 cgtattagtc cgattgagtt ttacattcac cagtacaaac ctgaaaatag tgaaaatctg
     1201 caggcccaga ttgagtttat tgaaaaaata gctcccttga ttgttcgaga aaaatctatt
     1261 actgctcaaa acagctatat tcatatttta gctgacagtc tggcgtcctt tgattatgct
     1321 cagattgagc agattgttaa tgagagtcgt caggcgcaaa ggcagaatcg catggaaggg
     1381 gtttccagac cgacgccaat cactatgcct gtcaccaagc agttatcggc tattatgagg
     1441 gcagaagctc atctacttta tcgaatgatg gaatctcctc ttgttttgaa cgattaccgt
     1501 ttgcgggaag actttgcatt tgccacacct gaatttcagg tcttatatga cttgcttggt
     1561 cagtatggca atcttcctcc agaagttcta gcagaacaga cagaggaagt tgaaagatct
     1621 tggtaccaag ttttagctca ggatttacct gctgagatgt caccgcggga actaagtgaa
     1681 gtagaaatga ctcgaaacaa ggctctcttg aatcaggaca atatgagaat caaaaagaag
     1741 gtgcaggaag ctagccatgt aggagatacc gacacagccc tagaagaatt ggaacgttta
     1801 atttcccaaa agagaagaat ggagtaataa tggcaacaaa acaaaaagaa gtaacaacat
     1861 ttgacgtaca agtagcagaa tttatccgta atcataagca aaaagggaca gcaacagatg
     1921 atgaaatcaa tgctagtctt gtcgttcctt ttaccttgga cgctgatggg attgaagatc
     1981 tcttgcaacg gattcaggat gcgggaattt ctatcacaga taacgaagga aatccaagtg
     2041 cgcgtgttct tagcaatgaa gaagaaccag aactcagcga tgaggacttg attgggtcaa
     2101 cttctgctaa ggtcaatgac cctgtccgta tgtacttgaa agaaataggg gtcgttcctc
     2161 tcttgaccaa tgaagaggag aaagagttgg cactggctgt tgaagctggt gatatcgaag
     2221 ccaaacaacg tcttgcggaa gccaatcttc gtttggttgt ttccattgcc aaacgctatg
     2281 tcggtcgtgg catgcagttc cttgacttga ttcaagaagg aaatatgggc ttgatgaagg
     2341 cggttgacaa gtttgactat tctaaagggt tcaagttttc aacttatgca acttggtgga
     2401 ttcgtcaggc tatcactcgt gctattgcgg atcaagctcg taccatccgt atcccagttc
     2461 acatggttga aactatcaat aaattggttc gtgaacagcg gaatctcctt caagaattgg
     2521 ggcaagatcc gacaccagaa cagattgctg aacgaatgga tatgacacct gataaggttc
     2581 gtgaaatctt gaagattgcc caagaaccag tatctcttga aactcctatc ggtgaagagg
     2641 acgatagcca ccttggagac tttatcgaag atgaagtgat tgaaaatcca gtggattata
     2701 cgactcgtat cgtcttgcgt gagcaattgg atgaaatctt agatactctt acagaccgtg
     2761 aagaaaatgt tctgcgtcta cgttttggac tagatgatgg aaaaatgcgc acacttgaag
     2821 atgtggggaa agtctttaac gtaactcgtg agcgtatccg tcagattgaa gcaaaggctt
     2881 tgagaaaact acgccaacca agtcgcagca aaccgcttcg tgattttatt gaagactaag
     2941 agtgaggaaa atatggctta tacagaagag caaattgaaa acatcaaaac acggatttta
     3001 acagccttgg aagaagtcat cgaccctgag ttgggaatcg atattgtcaa tcttggtttg
     3061 atctatgaga ttcgttttga cggtgacaca gggcaaacag agattgacat gactttgaca
     3121 actatgggtt gtcccttagc agaccttttg acagaccaga tttatgatgc tatgatagag
     3181 gttccagaag taacggatac tgaggttaaa ttagtctggt atccagcctg gacagttgaa
     3241 aaaatgagtc gctatgcccg cattgcccta ggcattaagt aaacatataa aagcatgtga
     3301 gagactgttg gaaaagcgag gaaatttccc ctcttttcct ctagtctctc ctttcttttg
     3361 ctgattttat tcaaagaaaa tgatataata gtagttatgg agaaaaagaa attacgcatc
     3421 aatatgttga gttcaagtga gaaagtagca ggacaaggag tttcaggtgc ttaccgtgaa
     3481 ttagttcgtc ttcttcaccg tgctgccaag gaccaattga ttgttacaga aaatcttcca
     3541 atcgaggcag atgtgactca ctttcatacc attgattttc cctattattt atcaaccttc
     3601 caaaagaaac gctcagggag aaagattggc tatgtgcatt tcttgccagc tacacttgag
     3661 ggaagtttga aaattccatt tttcttaaag ggaattgtga aacgctatgt attttctttt
     3721 tacaaccgga tggagcactt ggttgtggtc aatcctatgt ttattgagga tttggtagca
     3781 gctggtattt cacgtgaaaa agtgagctat attcctaact ttgtcaacaa ggaaaaatgg
     3841 catcctctac cacaagaaga ggtagtcaga ctgcgcacag atcttggtct tagtgacaat
     3901 cagtttatcg tagtaggtgc tgggcaagtt cagaaacgta aagggattga tgactttatc
     3961 cgtctggctg aggaattgcc tcagattacc tttatctggg ctggtggctt ctcttttggt
     4021 ggtatgacag atggttatga acactataag aaaattatgg aaaatccccc taaaaatttg
     4081 atttttccag gcattgtatc gccagagcgg atgcgcgaat tgtatgctct agcggatctt
     4141 ttcttgttgc ctagttacaa tgagctcttt cctatgacta ttttagaagc tgcgagttgt
     4201 gaggctccta ttatgttgcg tgatttagat ctctataagg tgattttgga gggaaattat
     4261 cgggcgacag cgggtagaga agagatgaaa gaggctattt tggaatatca agcaaatcct
     4321 gttgccttaa aagatctcaa agaaaaggct aagaatattt ccagagagta ttctgaagag
     4381 catctgttac aaatctggtt ggacttttat gagaaacaag ccgctttagg gagaaagtaa
     4441 aaagtgaggt aatctatgcg aattggttta tttacagata cctattttcc tcaggtttct
     4501 ggtgttgcga ccagtattcg aaccttgaaa acagaacttg aaaagcaggg acatgctgtt
     4561 tttatcttta cgacgacaga taaggatgtc aatcgctacg aagattggca aattatccgc
     4621 attccaagtg ttcctttctt tgcttttaag gatcgtcgct ttgcctaccg aggttttagc
     4681 aaggcacttg aaattgctaa acagtatcag ctagatatta tccatactca gacagaattt
     4741 tctcttggcc tgttggggat ttggattgcg cgtgaattga aaattccagt catccatacc
     4801 tatcacaccc agtatgaaga ctatgtccat tatattgcta aggggatgtt gatccggccg
     4861 agtatggtca agtatctggt tagaggtttc ctgcatgatg tggatggggt tatttgccct
     4921 agtgagattg tccgtgactt gctatctgat tataaggtca aggttgaaaa acgggtcatt
     4981 cctactggga ttgaattagc caagtttgag cgtccggaaa tcaagcagga aaatttgaaa
     5041 gaactgcgta gtaaactagg gattcaagat ggtgaaaaga cgttgcttag tctttcgaga
     5101 atctcctatg aaaaaaatat tcaagcagtt ttagcagcct ttgctgatgt tctgaaagag
     5161 gaagacaagg ttaaactggt agtagctggg gatggccctt atctgaatga cctcaaagag
     5221 caagcccaga acctagagat tcaagactca gtcatcttta cagggatgat tgctcctagt
     5281 gagacggctc tttactataa agcggcggat ttcttcattt cggcatcgac aagcgaaacg
     5341 caaggtttga cctacttgga aagcttagcc agtggaacac ctgtcattgc tcacggaaat
     5401 ccttatttga acaacctcat cagtgataaa atgtttggaa ccttgtacta tggagaacat
     5461 gatttggctg gtgctatttt ggaagccctg attgcaacac cagacatgaa cgagcatacc
     5521 ttatcagaga aattgtatga gatttcagct gagaactttg ggaaacgagt gcatgagttt
     5581 tatctggatg ctattatttc aaataacttc cagaaagatt tggctaaaga tgatacggtc
     5641 agtcagcgta tctttaagac agttttgtat cttccgcaac aggtggttgc tgtacctgta
     5701 aaaggttcta gacgcatgtt gaaggcttca aaaacacagt tgatcagtat gagagattat
     5761 tggaaagacc atgaagaata gaaagaggaa cagtatgaaa aaacaattaa tgagaagcgg
     5821 tcgtgataaa aagattgctg gtgtttgtgc tggggtagcc cattattttg atatggatcc
     5881 tactattgtt cgcgtaatat ggggtgttct tgcttttggt tatggagcag gagttatagc
     5941 ttatatcatt ttatggatta tcgcacctgt agtaactgac tattgaaaac tagctaaatt
     6001 catgctaaga taatagaaaa tagaatgcaa cgaaggagag aaaaatggca tttggagata
     6061 atggaaatcg taaaaaaact atgtttgaga aaataacctt gtttatcgtg attatcatgc
     6121 tagtagcaag tttattggga atttttgcaa ctgcaattgg tgccctcagt aatctataaa
     6181 atagattcaa gaaaatttag tgactgggat ttcccagccc ttttttaaag tgagaagaaa
     6241 aaatgagtat gtttttagat acagctaaga tcaaggtcaa ggctggtaat ggtggtgatg
     6301 gcatggttgc ctttcgccgt gaaaaatatg tccctaatgg tggtccttgg ggtggtgatg
     6361 gtggtcgtgg aggcaatgtg gtcttcgttg tagacgaagg actacgtacc ttgatggatt
     6421 tccgctacaa tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc aaagggatgc
     6481 atggtcgtgg tgctgaggac cttagagttc gagtaccaca aggtacgact gttcgtgatg
     6541 cggagactgg caaggtttta acagatttga ttgaacatgg gcaagaattt atcgttgccc
     6601 acggtggtcg tggtggacgt ggaaatattc gtttcgcgac accaaaaaat cctgcaccgg
     6661 aaatctctga aaatggagaa ccaggtcagg aacgtgagtt acaattggaa ctaaaaatct
     6721 tggcagatgt cggtttagta ggtttcccat ctgtagggaa atcaacactt ttaagtgtta
     6781 ttacctcagc taaacctaaa attggtgcct accactttac cactattgta ccaaatttag
     6841 gtatggttcg cacccaatca ggtgaatcct ttgcagtagc cgacttgcca ggtttgattg
     6901 aaggggctag tcaaggtgtt ggtttgggaa ctcagttcct ccgtcatatc gagcgtacac
     6961 gtgttatcct tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca tatgaggatt
     7021 acctagctat caataaagag ctggagtctt acaatcttcg cctcatggag cgtccacaga
     7081 ttattgtagc taataagatg gacatgcctg agagtcagga aaatcttgaa gactttaaga
     7141 aaaaattggc tgaaaattat gatgaatttg aagagttacc agctatcttc ccaatttctg
     7201 gattgaccaa gcaaggtctg gcaacacttt tagatgctac agctgaattg ttagacaaga
     7261 caccagaatt tttgctctac gacgagtccg atatggaaga agaagcttac tatggatttg
     7321 acgaagaaga aaaagccttt gaaattagtc gtgatgacga tgcgacatgg gtactttctg
     7381 gtgaaaaact catgaaactc tttaatatga ccaactttga tcgtgatgaa tctgtcatga
     7441 aatttgcccg tcagcttcgt ggtatggggg gtgatgaagc ccttcgtgcg cgtggagcta
     7501 aagatgggga tttggtccgc attggtaaat ttgagtttga atttgtagac taggagactg
     7561 gtatgggaga taaaccgata tctttccgag atgcggatgg taattttgtt tccgccgcag
     7621 acgtttggaa tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca aatcgtgcct
     7681 tgagattggc acgaactaaa aaggaaaatc catctcagta aagaagctaa aaaatcccgg
     7741 ctctttgtca actgtagtgg gttgaagtca gctaagctcg agaaaggaca aatttcgtcc
     7801 tttctttttt gatgttcaaa gcgataaaaa tccgtttttt gaagttttca aagtttcgaa
     7861 aaccaaaggc attgcgcttg ataagtttga tgagattatt ggtcgcttcc agtttggcat
     7921 tagaatagtg tagttgaagg gcgttgacaa tcttttcttt atctttgagg aaggttttaa
     7981 agacagtctg aaaaatagga tg
//
LOCUS       DAVFJR010000066         7576 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVFJR010000066 DAVFJR010000000
VERSION     DAVFJR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.067"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(164..355)
                     /locus_tag="VU722_002056"
     CDS             complement(164..355)
                     /locus_tag="VU722_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU1772948.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(516..1190)
                     /locus_tag="VU722_002057"
     CDS             complement(516..1190)
                     /locus_tag="VU722_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772949.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(1196..1642)
                     /locus_tag="VU722_002058"
     CDS             complement(1196..1642)
                     /locus_tag="VU722_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1772950.1"
                     /translation="MKLRIEIDGNLEETEIVIRTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRFKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(1756..2259)
                     /locus_tag="VU722_002059"
     CDS             complement(1756..2259)
                     /locus_tag="VU722_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU1772951.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLDQQVGVYVFIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(2256..2618)
                     /locus_tag="VU722_002060"
     CDS             complement(2256..2618)
                     /locus_tag="VU722_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU1772952.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKVESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGIRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(2684..4543)
                     /locus_tag="VU722_002061"
                     /pseudo
     CDS             complement(2684..4543)
                     /locus_tag="VU722_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(4582..5031)
                     /locus_tag="VU722_002062"
     CDS             complement(4582..5031)
                     /locus_tag="VU722_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1772953.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQAVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRMVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(5155..5871)
                     /locus_tag="VU722_002063"
     CDS             complement(5155..5871)
                     /locus_tag="VU722_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1772954.1"
                     /translation="MGRKWSNIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(6752..>7576)
                     /gene="ply"
                     /locus_tag="VU722_002064"
     CDS             complement(6752..>7576)
                     /gene="ply"
                     /locus_tag="VU722_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU1772955.1"
                     /translation="IYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVA
                     YGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSG
                     ARVVTGKVDMVEDLIQEGSRFTADHPGLPTSYTTSFLRDNVVATFQNSTDYVETKVTA
                     YRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTAKAWDRNGQDLTAHFTTSIPLK
                     GNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKIEND"
BASE COUNT         2295 a         1744 c         1345 g         2192 t
ORIGIN      
        1 aggctgctca aaacactgtt ttgaggttgt ggatgaagct gacgtggttt gaagagattt
       61 tcaaagagta ttattcttat tgccaggcac ctaagttgcc aacgtagtaa ccatcaggtg
      121 tgtaggtatt gcgaagcatc ttacctgatg aagccagata atactacttg ccattgtctt
      181 tgacccaatc attcgcaatc atggaaccag aagaacttac ataataccat tctcccttgt
      241 cataaaccca agtactgact ttcatggttc ctgagcaatt aaaggcaaaa aaactgtcca
      301 atatcattcg ttttttaaaa gcatttgaca ctacatcatc tacgctgtag tacatagata
      361 catcaaacgt aaaagccaaa atatcgaaaa atatacaact tttaaaggca gcatttcatt
      421 ttttaaagtc taacaaccat agaactgaaa tcagagcaag gcatcaattt cctactctta
      481 gtacgtctat tttgatggtt gaagtgaaga tttttttatt taacgtagac aatttccaac
      541 ttcccaaaag ccacatctcc acggatagtc aaggttttgc tggttggggc tacaggagcg
      601 tcagccttag ctgcaccaaa ggaggtttct actttcaaat ctacacgcca gtgttgtgga
      661 acatagacgg ttgcatttcc gaaggccact tcaatattta aagttgcaaa atcacctagc
      721 atctctgcat tatcatagta gattttagca tccccaaaag cgacttccac ttggtcatct
      781 acgagatctt gatcttgctt atagaaggtc ccgctaccaa aagcgacttc cttatccgtg
      841 acgactgttt ttttcccatt gtaccaccat tttttttcat tccagaactt acttgaatgc
      901 gtcagataac caacaccaag taccaccaag atgctagccc aaataagaga atgattggta
      961 actggtaaca agtcataagc gtaatttgca atgatgagcg ccagtaaacc tgtaaaaact
     1021 gccgaagtga gatgacgtct aaggatggac tcaatggact tataagcaaa aaaaacaata
     1081 cctagtaaag gccatatttt accatccaaa gaaggaattc caaaattccc ttgcagcaag
     1141 atccaagctg ctaaaaccaa taaaacaata ccaaatgctt tctttttcat gttttttacc
     1201 tcatgtttct tagattttct tttaggaggg attggtaatg ccgtgagaca tgaacctcct
     1261 tgtgcgtctg atagaaggaa atggtgcccg ttcctgaaaa ggacttgtcc actgagtaaa
     1321 tctgacggat gtttgcgatc gttgacttgg aaactcgatt aaaatagcga ggcaagatag
     1381 attccaactc atagagcttg aagcgaacct cataagcttc cttctggtta tgagcgtaga
     1441 tcttgctccc ttctgtttca aagaagagaa tttctgacag gtctagataa tattcacctg
     1501 tccccttgta aaaagtcaac ctcggagcct ttgactcttg caagagccgt tgcaagtctg
     1561 caatttcatc tgtcaaagtg ggggtcctga tgacaatttc agtctcctct aaattaccgt
     1621 caatctcaat tcgtaacttc atcacatctc ctttctgact ctactatatc aaagctaagt
     1681 taggaataca agggcaaaaa agcaagtggt caatttgaag cagtaagtgg ttgtaggact
     1741 agcttaactt acatgtcaga ataggaagaa aaggaatccc cacaccagac cacaagcata
     1801 gccaaccaag acatccttgg gataatgaac accccctaaa accctcacca accccagcaa
     1861 agctgaaaag atcaagcata ctaagccaat aggtagacta gcatgcagac aggccatgga
     1921 gatgatagtt gccgaaaaga catggcgact gggcatcgac cgtcccgaac tatccttatc
     1981 aagaagggga cagatatccc aagtttcata aggtctcggg tgattgattt tcttacgaaa
     2041 cagggacaag gccacaaaac ctgatgcagg aataaacaca taaaccccaa cttgctgatc
     2101 aagtcctagt tgcaggtaag tggtgactag caagatcaga tagaccaggg gcatggcgac
     2161 tgtcatcaaa cgattgaaac tgcgtaatag gaataaaaga attggacgac tagttagtct
     2221 ggagctgata tttcgatacc attcttgata atttttcatt tatgcttctc atacttttct
     2281 agaacttgtt gagatgtttt ccccttggca agccaatcca ctagcttgtc caagcgacgt
     2341 atttcctgca tcagaggatc atcaatttcc tcaatacgga taccgcaaat cttccctgta
     2401 attgcaattc gttcagggac ataatatggt gcttgtcgaa aaaaatctcc gtaagtaaca
     2461 tccctatcca gacaagcaag aacgtcactc acttcatacc ctgtcaacca actggtcact
     2521 tggtgaactg actctacctt tccacccttt cgctcaactt ttgcaatcaa ggctaagtag
     2581 acagcagcaa atttcatatt gtataatttc tgactcatac ttctctcttt ctatgtgtac
     2641 tagtataaat cagaaaaaga aggccgtcaa gccttctttt gatttattct tctgcttcat
     2701 cttctgtaaa ttgactattg tacaagtcag cgtagaagcc accttgcgcc atcagttcct
     2761 catagttgcc ttgctcgatg atatttccat ctttcatgac caagatcaaa tctgcatttt
     2821 ggatggttga caagcggtgg gcaatgacaa aggatgtgcg tccttccatc aaacggtcca
     2881 tggctttttg gatcaattcc tctgtccgtg tgtcaacaga agaagtcgcc tcatccaaaa
     2941 tcaaaagcgg tccatcctta agaagggcac gagcaatagt caatagttgt ttttgtccta
     3001 cagacaaggt cacggtgtca tccaagatgg tatcatagcc atctggcaag gtcataataa
     3061 agtggtgaat tcccacagcc ttactagctt ccatcattcg ttcatcacta atccctattt
     3121 gattatagat gagattgtcc cgaatagttc cttcaaagag ccaggtatcc tgcaagacca
     3181 ttgaaaaagc atcatgcact tctgaacgcg tcatagcctt ggtatccaca ccatcaatgc
     3241 gaatacttcc cttatcaatc tcatagaatt tcatcaaaag attgacaatg gttgtcttac
     3301 cagccccagt cggcccaaca atggcaacct tttgaccagc atgagctgtc gcagagaagt
     3361 catagtcttg aacattgaca ccgtccacca gaatttctcc tgctgacacg tcgtagaaac
     3421 gtggaatcag attgaccaga gttgatttac cagaacctgt tgacccaata aaggccactg
     3481 tttgaccagt ttctgcttta aagctaacat gttcaataac tgcctccgaa tttgccgcat
     3541 agcggaaggt cacatcctta aactcgacct gacctttgaa gttttcatca gccagctgca
     3601 cttgaacaga gttttggata gaagaatgca aatctaaaac ttgattaatc cgcttagcag
     3661 agaccatagt tcggggaaga acgatgaaga gtgctcccat gagaaggaag cccatgacaa
     3721 cctacatggc ataagacatg aaaacaatca tgtcactaaa gagaggcaga cgcgctatcg
     3781 gagcaacgtc gttaatcaca taggccccaa tccagtaaat cgctacactc aaaccacttg
     3841 aaatccccat catgatagga ttcaaaatag ccataagacg gttgacaaac aaattcaaac
     3901 gggtcaattc atcatttact gctgcaaatt tttcattttg ataatcctct gcattgtaga
     3961 cacgaacgac acgaatacct gttaaactct cacgagtgat actgttcagt ttatctgtca
     4021 gcccctgaat caaggactgt tttgaaaagg ctagcgtcat caaaacggtc gtcatcagga
     4081 cgttgacaat cactgccaca agtacggccc agagtcagta ttctgaatga cctaaaatct
     4141 tcccaatagc ccagatagcc ataattgaac cacgcgttac cacttgcaag cccatagtaa
     4201 tcaacatttg aacttgagta atgtcattgg tagtacgcgt caagaggcta ggaattgaaa
     4261 atttcttaat ctttgtctgc gagtaatcca aaactcggtt aaaaatatca cttctcagcc
     4321 tactaatata agaagccgcc actcgggatg caaaaaatcc aactgcaact acggacaaga
     4381 aggcaagaaa gggcattccc atcatcatgc ttgccggctg ccacaactca tctaaattag
     4441 ttccttgact acctagcaaa tccgtaattt tcgagatata ggtcggcact tccaactcta
     4501 gatagaccga aaagcaagta aagagaatgg ctagtaaaat catcccccat tcttttctac
     4561 taattctttt ggctaatttc tttattctct cctcctattc ccttgatatt ttgcctgtag
     4621 ttgaccgaga actttctcaa aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg
     4681 cttgtctatg cgttcaaaaa aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt
     4741 cagacgaaca aacttagccc gcttatcaac aggactcgcc tccaattcca ccaaaccatt
     4801 ttgcaccata cgcttaacca gattactagc aacagacttg gtaatattga gttcctgctc
     4861 gatatcttta atcaagacca agtcttggtt tttctcgcga ttatccaaaa aacgcacagc
     4921 ctgaccttgc ggcccaccca taaattcaat gccgcaacgt ttggcttcct tttgcaccat
     4981 caggtgaatt tgatgaccaa aacgcttaaa gactaacatc ggtttatcca taatctcccc
     5041 cttctaaata aaaatagttc tctggagaat aattaaattt ctatgagaac tattttcttg
     5101 attaaaaaaa tcccaagtga ttttctcact taggatcatg ttctataggt taaattaaaa
     5161 cccatctacg ttcgtataaa tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag
     5221 tttttcaaag gtttcaaggt cttcgcctga caattccact tctgactgag gaatcatttc
     5281 caattcagtc acttggaatt cttcaatacc agactcacgg agggcaacga tagccttgtg
     5341 aaggtcagtt ggcgctgtgt aaactgtgat tgtaccttct tgtgcttcta cgtcatccac
     5401 atccacatcc gcttcgagca attgctcaaa gactgcgtcc gcatcttcac ctccaaatac
     5461 aataacacct ttgttgtcaa agaggtaaga aacagaacct gaagcgccca tgtttccgcc
     5521 gtttttacca aaggctgcac ggacattggc tgctgtacgg ttaacgttag aagtcaaagt
     5581 atccacaatt agcatagagc catttggccc aaaaccttcg taacgtcctt ctgtaaaggt
     5641 ttcgtctgtg tttcctttgg ctttatcaat cgctttatcg ataacgtgtt ttggcacttg
     5701 ggcttgttta gcacggtcga taacgaattt caaagctgag tttgattctg gatctggatc
     5761 acctttttta gctgctacat agatttctac accaaatttt gcatatactt tagagttggc
     5821 tccatcttta gccgttttct tggctacgat attggaccat ttacgtccca ttaggaatct
     5881 ccttttttca cattttaatc tttcttatta taacacaagt ttttttgatt ttcactagag
     5941 gaaatgggtt ttattagcaa atcaagctag gatagtactt tacctgctaa gatggtcttg
     6001 cctttctatc tttatcaaca gacactcatc cacattcaaa aaacaaacta gaccattatc
     6061 tgcaaataga aagtttcagc caagtttgac aaagtcagct caaattactg tttgaagttt
     6121 gtagatataa gcgacaaaaa caatcatact gcaccttttg ttgacagtct actccagaca
     6181 tatcatagtt caagtaaata ctttgaaatc caacagttct tataggtgct attgtattct
     6241 aagaaatcaa tagaagagtt tctaagcaaa tctctaatac tcaataaaaa tcaaagagca
     6301 aactagaaag ctagccgcag gttgctcaaa acactgtttt gaagttgcgg atagggctga
     6361 catggtttga agagattttc gaagagtata atttacgtgt tcccaagatg gagaagttag
     6421 actagtacac tggcacttct aaaccattgc tagcaattga tttgttcata tttaatttca
     6481 ttttttccat aaatgggtat tagatataaa cagcaaaata tttccgatac gtgtcattct
     6541 tgaatttcca atcatctaaa acaagtaaag gataatcaat cccctgtata tcaaggaatt
     6601 ggctaccctt tttacttttt tacacattct gtttgataga ttcattttaa catcacgagc
     6661 atactccaat ggaaatcgct aggcaagaga taaactttca gatatccgca gagagatcat
     6721 cgcctctttt tgtcgcaagc attctcctct cctaatcatt ttctatctta tcctctacct
     6781 gaggataaag agtcgttccc caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg
     6841 ttttttcata aaccgtacgc caccattccc aggcaagccc ggtacactct ctaattttga
     6901 cagagagatt acgaacattc ccttttaaag gaatactagt ggtaaagtga gccgtcaaat
     6961 cctgcccatt tctgtcccaa gccttagcag ttaagacttc cttaccttga tgatcatagg
     7021 ataattcatc ccaagtaata taatattggg caacataggc accactatga tccagcagta
     7081 aatctccgtt tctgtaagct gtaaccttag tctcaacata gtctgtactg ttttgaaagg
     7141 tcgcaactac attgtcacgt aaaaaagaag ttgtatagga agtcggcaag cctggatgat
     7201 ctgctgtaaa gcgactgcct tcttgaatca agtcctctac catatccacc ttgcctgtta
     7261 caactcgggc acccgaactc gggtctcccc ctaaaataac cgccttcact tctgtattgt
     7321 ccaaaatctg cttccactct gtctgaggag ctaccttgac tccttttatc aaagcttcaa
     7381 aagcagcctc tacttcatca ctcttactcg tggtttccaa cttgagatag acttggcgcc
     7441 cataagcaac actcgaaata tagaccaaag gacgctctgc agaaattcct ctctgcttta
     7501 aatcctctac cgttacagta tcttgaaaca catctcctgg atttttaaca gcatctacgc
     7561 tgactgtata ataaat
//
LOCUS       DAVFJR010000067         7386 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVFJR010000067 DAVFJR010000000
VERSION     DAVFJR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.068"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..548
                     /locus_tag="VU722_002065"
     CDS             <1..548
                     /locus_tag="VU722_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1772956.1"
                     /translation="VKDGIIDGDRGKNYPKSDELFSEEYCLFLNTKNVTKNGFSFDTK
                     QFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRINSGMLILRPKTP
                     NLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFADFVTLVDK
                     SQFACEIAIKVWRNSLKFSII"
     gene            578..3928
                     /locus_tag="VU722_002066"
                     /pseudo
     CDS             578..3928
                     /locus_tag="VU722_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            4199..4354
                     /locus_tag="VU722_002067"
     CDS             4199..4354
                     /locus_tag="VU722_002067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772957.1"
                     /translation="MKIKEQTRKLAAGCSKHGFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(4471..4941)
                     /locus_tag="VU722_002068"
     CDS             complement(4471..4941)
                     /locus_tag="VU722_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1772958.1"
                     /translation="MNKSEHRHQLIRALVTKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4958..7231)
                     /locus_tag="VU722_002069"
     CDS             complement(4958..7231)
                     /locus_tag="VU722_002069"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU1772959.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFNLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSENELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEQPQLNLVQPQGQAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRRRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVIFTHGSQDWNVKPLHVYQIFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2310 a         1236 c         1574 g         2266 t
ORIGIN      
        1 ctgtcaaaga tgggattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt
       61 tgtttagtga ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt
      121 cattcgatac aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac
      181 ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg
      241 atgaattaat aaaatataaa catttacgta taaattcagg tatgctaata ttacgtccca
      301 agacaccaaa tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc
      361 gagtgatatc aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc
      421 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtaacc ctggtcgaca
      481 aatcacaatt tgcttgtgag atagctataa aagtgtggag aaatagcttg aaatttagta
      541 taatatagct aaactatttg tttaaagtga gaaaaaaatg ggaaatttta gctttctttt
      601 aaaaaatgac gaatatgaat ctttttcaaa accttgcatt gaagctgaaa atatgattgc
      661 tacatcaact gtggctactg cctttatggc gcgtcgtgct ttggagcagg ctgtccattg
      721 gatatatagt cacgattcat atttagaagc tccctatcgt gctactctat cttctttagt
      781 atgggatgat gattttaggg atatcgtaga ttctgaactc cacaagcaga tagttctgtt
      841 gattcggtgg ggaaaccatg ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt
      901 agctttacat catttgtatc agtttgttaa ttttatcgat tattgttaca gcaatgaatt
      961 tgtggagcgt tattttaatg agaagtgctt accactttca gcaaacatca aataccgaga
     1021 aactccacaa tctatgataa agttacaaga cagtttacca gaactgcctg attttcatga
     1081 acagatggct gctcagtccg tagaagttca agagacttat actgaaaaac gtgagactgc
     1141 agcgcaacgg caagatgtgc ctttccatat tgaacaatta tctgaggcag agacaagaaa
     1201 gctctttatt gatatcgatc tccgtttagc aagatggata tttgaagaaa actgtcgtgt
     1261 tgagatagcc gttgatggtc tcaagcacgg ttcaggaatt ggttactgtg actatgtact
     1321 ttatggtaaa aatgggaaaa ttttagcgat tgtagaggct aaaaaagcct ctgtcaatcc
     1381 agaagtaggg gaagtacagg tcaaagaata tgctgaagct cttgagaaac atatcggcta
     1441 tcagccaatt tgctttatta caaatgggtt gaagcactat atacttgatg gtccgaaccg
     1501 acgccagatt gcaggctttt actctcaaga agaattgcaa ttagtgatgg atagacgtca
     1561 tcttcaaaaa ccacttgagg atatttctag taaaattaga gacgatattt ccgggcgtta
     1621 ctaccaaaaa catgcgattg caagcgtttg agaagctttc tctgatcatc gtagacaggc
     1681 acttttggtt atggcaactg gggctgggaa aactcgtaca gcagtttctc tagttgatat
     1741 cttatcacgt cataactggg taaaaaacgt tctcttctta gccgatagaa cttccttggt
     1801 taagcaagta tatgattcgt ttagaaaatt actcccagat ctttccgttt gtaacttctt
     1861 agaagataaa gaaggagctc aatcaagtcg catggtcttt tcaacttatc cgaccatgat
     1921 tggagcgatt agtggtcaag aagaagtaaa tcaacgccct ttcactgttg ggcattttga
     1981 ccttatcata attgacgaat ctcaccgttc tatttatcag aaatacaagt ccatttttga
     2041 ttattttgat gcaagaattg taggcttaac agctactccg cgtcaagatt tagataaaaa
     2101 cacctatgga ttctttaatt tggagaatgg ggttccaaca tatgcatatg atttggaaga
     2161 ggctgttaaa gacggatatt tagtagccta tcattctatc gaaaccaaac tgaaactacc
     2221 tacggatggt ctacattatg atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa
     2281 atttgaagac gatatctgtg aaaaagatat tgatgggagt gtatttaatt cctttatttt
     2341 caataaaagt acagtagaaa ttgttttaaa tgaactcatg acaagaggaa ttcagacagc
     2401 ctcgggtgat gaaattggta aaactattat ttttgctaaa aatcatgatc atgcggaata
     2461 tatcagaggt atttttaaca accgctatcc tgaaaaaggg agcgactatg ctcaggtgat
     2521 tgattatagt attaagcatt atcagacctt gattgatgat tttaaaatta aggagaagta
     2581 tcctcaaatt gcgatttctg tcgatatgtt agatacaggt attgatgtat cagaggttgt
     2641 taatttagtc ttcttcaaga aagtacgctc taaaactaag ttttggcaga tgattggtcg
     2701 aggaacccgt ctatgtaaag atttatttgg acctgagcag gataaggaaa acttcttggt
     2761 atttgattat ggggacaatt ttgattattt tcgtgcagat ccaagagatg gagagggtcg
     2821 tcacattgtt tcgttgactc agcgtttatt taatatcaaa gtggacttga ttcgagaact
     2881 tcagggactc caataccaag aagatcagtt tgcgagagca taccgtcagc agcttgtctc
     2941 ggaacttcaa ggtcgtatag agagcttaaa tgagttggac ttcagggttc gtatggtttt
     3001 aggtacagtt tatagctata ggaaattgga aagttggcag aatctaactg ctgttacaag
     3061 tgaaaccatt caaaaaaatc tctctccgct tttatttgat gaagataaag aagatgagat
     3121 ggcgaggaga tttgatttgt ggttgcttca tattcagttg gggcaactga cagctaaatc
     3181 ttccactgtt catatttccc aagtgatgaa gacggctaga gctctttctg ctattggcaa
     3241 tatcccgcag gtttttgagc aggctgaaat tatcaggaaa gtacaggagc ctgaattttg
     3301 gaaagaagtt aacttgtctg atttggaaaa aattcgtctt gctattcgag atttattaca
     3361 gtttttggat aaaacagacc gtaaactcta ctatattaac tttgaagatc gtatactctc
     3421 cactgttcac gagaccacag catttttgca ggtcaacgat cttcggtctt acaatgaaaa
     3481 agttgagcat tatttgaaaa ctcatctgga tgaggagtcc atttctaagc tataccataa
     3541 taaaaagttg acatctgatg atatgcttgc acttgaaaaa ttgctctggg aaaaattagg
     3601 tagtaaagca gactaccaaa gtcattatga aaataaggca attccgagat tggttcgtga
     3661 gattattggc ttagatagag agtctgccaa tcgtattttt tctaaatttt tgtcggatga
     3721 gaatcttaat gccaggcaga tttcatttgt aaaattgatt gtagactaca ttgtagaaaa
     3781 tggtttttta gagacgaaag tgttaacgca agagccgttt aaatcttatg gttctgttca
     3841 actactcttc caacaccaac taccagtact tcgtaatatt gttcaaatca ttgaacttat
     3901 caataatcga gctggagaag cggcttaaat tctaaagtga ttgccatgct gagactcatt
     3961 taaaattaaa aagagtagaa atttatgcta tatatgagaa gttttattag gaagaatgtc
     4021 atcgttttcc tagaatacag tatcagttgt taagtggttg ataaatttca aagtagatac
     4081 ttgtaccacg atgtttgttg atcgagttat taacaaaaga gctactttga ttttaaagaa
     4141 atagaaaaca aaaagccgag caagaattca attgcaggag aaaatgaaat aatactcaat
     4201 gaaaatcaaa gagcaaacta ggaaactagc tgcaggctgc tcaaaacatg gttttgaggt
     4261 tgtagatgaa actgacgaag tcagtaacca tacctacggc aaggcgacgt tgacgcggat
     4321 tgaagagatt ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca tagtatcaag
     4381 ggttttcaac acttgatact atgcgttttc tgatgttaaa gactttctac caggtttttt
     4441 aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg gtggggcgaa
     4501 ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga tgataagaca
     4561 gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat caatgataga
     4621 accgaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt gaactgggcg
     4681 catccagaca agggcatctt ccatgtagag ttcgagacgt ttttcccatt ttgagatgga
     4741 accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata ggttcatatt
     4801 tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttctcag caagaagggc
     4861 ttgcaactca gcctgtgtat gaatcttgtt ttttgtgaca agagcgcgta taagttggtg
     4921 gcggtgttct gatttattca taataatgta attcctttta gcaaggtaag gtaagcatgg
     4981 actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg atttcaaagt
     5041 cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa atagttggct
     5101 gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact aacagtaaat
     5161 catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc tctggtctaa
     5221 atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg gttctagcac
     5281 ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc agttgggcag
     5341 ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg cgaccgttta
     5401 ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc ccttgataga
     5461 gctctgtatt gaaggcttgg tatgtcttac catagcgctc aaaatcctta tctgggtact
     5521 ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt tcttgcccac
     5581 cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag ataacagtag
     5641 gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca tttatggact
     5701 cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta tggaaaaaga
     5761 gatgcttgtg tatatgagta ggaagagcat ggaagatctg gtaaacatga agtggtttga
     5821 cattccaatc ctgagaacca tgagtaaaga taacctctgc ctttacttta tgggcattga
     5881 gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg tctagctgag
     5941 ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag tcgccagcta
     6001 agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct ggataaccac
     6061 ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa attcctgcct
     6121 cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg gacatggtac
     6181 ctagatagga aagtcctgtt gtagcaactt ttccgtttga ccaatcagcc ttgacttgac
     6241 gctggcgcgt gtgatcagta aaggcacggc gacggccgtt aagccaatcg atgacatttt
     6301 tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag tctttggtac
     6361 caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg tttagtgtat
     6421 agctagagtt gatgtgagtt agcttttcct cagcctctgc tacaagctca gcttgacctt
     6481 ggggttggac gagatttagt tgaggttgct ctagctcaat cttgtgagga agcttaacct
     6541 caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg gttccctgat
     6601 gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg cgaataatgc
     6661 taacctttac taggtctggt agcccttttt ggtcagtatc gacacgagac tcaacgtaaa
     6721 cgacttcacg aatgacatcc tggctagaaa aagtagccaa actcttgccg ttaaagtagt
     6781 ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata agagtatttc
     6841 cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca ccatatataa
     6901 tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc aaataagcaa
     6961 agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca ttttccgatt
     7021 gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatggaaagt gggtagttgg
     7081 tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct ttgtgattgg
     7141 ctgtattttg taaattaaag ccacattttt ttagttcaga taagacattt tcttttggaa
     7201 aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg acagttaagg
     7261 ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa ataatccaat
     7321 aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag aataatagat
     7381 agggta
//
LOCUS       DAVFJR010000068         7219 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVFJR010000068 DAVFJR010000000
VERSION     DAVFJR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.069"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            703..1824
                     /gene="mnmA"
                     /locus_tag="VU722_002070"
     CDS             703..1824
                     /gene="mnmA"
                     /locus_tag="VU722_002070"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU1772960.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVIAVADQISIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLNQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVAGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFMREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1965..2420
                     /locus_tag="VU722_002071"
     CDS             1965..2420
                     /locus_tag="VU722_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1772961.1"
                     /translation="MTQQDFRTKVENTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEGAVVREVREELGVKAQAGQLAFVVENHFEQDGVYYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTTLPDWDGQLKHIHREE"
     gene            2430..4343
                     /gene="mnmG"
                     /locus_tag="VU722_002072"
     CDS             2430..4343
                     /gene="mnmG"
                     /locus_tag="VU722_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU1772962.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEAMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPVNIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4550..4642)
                     /locus_tag="VU722_002073"
                     /pseudo
     CDS             complement(4550..4642)
                     /locus_tag="VU722_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4696..6375)
                     /locus_tag="VU722_002074"
     CDS             complement(4696..6375)
                     /locus_tag="VU722_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU1772963.1"
                     /translation="MAYTLKPKEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKTP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6377..6610)
                     /locus_tag="VU722_002075"
     CDS             complement(6377..6610)
                     /locus_tag="VU722_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU1772964.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
BASE COUNT         2034 a         1456 c         1689 g         2040 t
ORIGIN      
        1 gctatagagt caatgccaat ggtgaatggg tttaagccga ttcaattaaa tcatgttaag
       61 aacatttgac attttaattt tgaaacaaag ataaggttcg attgaataga tttatgttcg
      121 tattctttag gtacctatct tatgatttca ggaagtgtca ttaaaaaaac gactcctttt
      181 ctctaacttg aaaaatagat tagagaaaat gggttgtttt atttattata gttatttgaa
      241 tgaaaataag aagaaggtat actcacgtca ttcacatgat ctgtatattg actataagtt
      301 ttaaaaaaca atttttaagc tctttcttgt cttctctaac caagcgtgtt ataatgaata
      361 ctgctcaagc gaccttcaat cgttaagcac acacgacctt caatcgtgaa ctagtcattt
      421 cgtttatctt ttattacgtc gttaactcga aataagatgc aagctgagct tgtctgattt
      481 ataacctcaa tcagtctccc agactgattg agcgaactca agttatgcct gcgactcgtt
      541 gcctatcata ttttcatttt aagatgatag gctaaaatgg tcttccagac cattttacta
      601 ctaaaagcaa acgaaatgac tatactcaaa taaattctat tgaaagtcat agtaaataga
      661 attttgaggg gtataaataa acgaatagat gggagactta ccatgagtga taactctaaa
      721 acacgtgttg ttgtggggat gagtggtggt gttgattcgt cggtgacggc tcttttgctc
      781 aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga cacagatgaa
      841 aacggcgttt gcacggcgac cgaagattac aaggatgtga ttgcggtggc agaccagatt
      901 agcattccct actactctgt caattttgaa aaagagtact gggaccgcgt ttttgagtat
      961 ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg caacaaggaa
     1021 atcaagttca aggccttttt ggactatgcc atgaccttgg gggcagacta tgtagcgact
     1081 gggcattatg ctcgagtggc gcgtgatgag gacggcactg ttcacatgct tcgtggcgtg
     1141 gacaatggca aggaccagac ctatttcctc aaccaacttt cgcaagaaca actccaaaaa
     1201 accatgttcc ctttgggaca tttggaaaag cctgaagtac gcagactagc agaagaagca
     1261 ggcctggcga ctgctaagaa gaaagattcg acagggattt gttttatcgg agaaaagaac
     1321 tttaaaaact tcctcagcaa ctacctgcca gctcagcctg gtcgcatgat gactgtggct
     1381 ggtcgcgata tgggcgagca tgcaggtctt atgtactata caatcggtca gcgtggcgga
     1441 ctcggtatcg gtgggcagca cggcggtgac aatgcccctt ggttcgttgt cggaaaagat
     1501 ctaagcaaga atattctcta tgtaggacaa ggattctacc atgattcgct catgtcaact
     1561 agcctagaag ccagtcaagt ccattttatg cgtgaaatgc cagaagagtt tacgctagaa
     1621 tgtacggcta aattccgtta ccgtcagcct gattctaagg tgacagtaca tgtcaaagga
     1681 gaaaaggcag aggtcatctt tgcggaacca caacgcgcga ttacaccagg acaggcagtt
     1741 gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc ttaccgcgat
     1801 ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac aataataaca
     1861 gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc tgcacttctt
     1921 tgtagttttg actgtttttg tgtcgtttaa gggaaaggat aaaaatgact caacaagact
     1981 ttcggacaaa agtagaaaat acggtttttg gtgttcgggc gacagccttg attgtccaaa
     2041 atcacaagct tctagttacc aaagacaagg gcaagtatta cactattggc ggtgcgattc
     2101 aagtcaatga aagcacggaa ggcgcggtag tccgtgaagt tagggaagaa ctgggtgtca
     2161 aagctcaagc tggccagcta gcttttgtag ttgaaaatca ttttgaacaa gacggtgtct
     2221 attatcacaa tatcgagttt cattatctgg tagacttact tgaagatgcc ccattgacca
     2281 tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag cttgaggata
     2341 tccagctagt tccagccttt ttaaaaacaa ccctacccga ttgggacggc caactaaaac
     2401 acattcatcg tgaggaatag gagagaaaca tgacttatca ttttactgaa gaatacgata
     2461 ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttagctgct agccgtatgg
     2521 gctgcaaggt cttgcttgcg accatcaata ttgaaatgct ggctttcatg ccttgtaatc
     2581 cctctatcgg tggttctgct aaggggattg tcgtacgtga agtcgatgcc ctcggtggcg
     2641 agatggccaa gaccattgac aagacttaca tccagatgaa gatgctcaac acagggaagg
     2701 gaccagccgt tcgtgccctt cgtgcgcagg ctgataagga actttactct aaggaaatgc
     2761 gcaagacagt tgaaaatcaa gaaaatctga cccttcgtca aaccatgatt gatgagattt
     2821 tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa tatgctgcta
     2881 aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc ggagacctca
     2941 agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac aatctcaagg
     3001 aactgggtct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc aaggcctctt
     3061 ctatcaacta cgacgtgaca gaaatccaac caggagatga agcgcctaat cacttctcat
     3121 acacttcacg tgatgaggat tatgtcaagg accaagtgcc atgctggttg acctatacca
     3181 atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg tttacaggtg
     3241 tggtcaaggg agtgggacct cgttactgtc cgtcgattga agacaagatt gtgcgctttg
     3301 cggacaagga acgtcaccaa ctcttccttg agccagaagg acgtaataca gaggaagtct
     3361 atgtgcaagg actttcaacc agtctgcctg aggatgtcca gcgtgacttg gttcattcca
     3421 tcaaaggttt ggaaaatgca gagatgatgc ggacaggtta tgctattgag tatgatatgg
     3481 tcttacctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt ctcttcactg
     3541 ctggtcagac aaatggaacg tcaggttacg aagaggcagc aggccaaggg attatcgcgg
     3601 gtatcaatgc ggctctgaaa atccaaggca agcctgagtt gattttgaag cgcagtgatg
     3661 gttatatagg ggtgatgatt gatgacttgg tgaccaaggg aaccattgaa ccctaccgtc
     3721 tcttgaccag tcgtgctgaa taccgtctca ttcttcgtca tgacaatgct gatatgcgct
     3781 tgactgagat tggccgcgag attggccttg tagacgatga acgctgggct cgttttgaaa
     3841 tcaagaaaaa tcaatttgat aatgagatga aacgcctaga cagtatcaaa ctcaagccag
     3901 tcaaggaaac caatgccaag gttgaagcga tgggattcaa accgttgaca gatgcagtga
     3961 cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggta gccttcatcg
     4021 gaccagctgc agaggatttg gatgataaga ttatcgaatt gattgaaaca gaaatcaagt
     4081 acgaaggcta tatttcaaaa gccatggatc aggtagccaa gatgaaacgt atggaagaga
     4141 aacgcattcc agtcaatatc gactgggatg acattgactc tatcgcaacc gaagcccgtc
     4201 agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt tcgggagtaa
     4261 acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt agtatttcta
     4321 aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt tcaaagcttg
     4381 gctttgattc atctccagcc tcccatagtt ccccgaacta tgggagctaa ctcaagttat
     4441 gctttcgctt agccttctag tctgatttcg atttttattg atactcttcg aaaatctctt
     4501 caaaccgcgt caacgtcgcc ttgccgtagg tatggctact gacttcgtca gttctatcta
     4561 caacctcaaa gcagtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattt
     4621 tcattgagta tgagttttaa tctcaaaaga aagcatagag aaaaacagct ccgaggacgg
     4681 ggctgttttc ttgctttatt cttcatctgg tgtgaggatc atcgggatga tgatcggttc
     4741 acgttcggta ttttcataga ggaaggggcg aatagcgttg acaatggcac cattgacaga
     4801 ttgcacgcta gcatccttat ttttcagtgc gatacgaatg gcattgaaga ggatacgctg
     4861 gctttggcga atcaagtcgc cagactctct catgtagaca aagcctcggc tgaggatgtc
     4921 tggaccagat agaatcatct gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc
     4981 gtcttcagat agatcgcgac gatctttgag gacagctgcg ccaatttcac cgatacgatt
     5041 tccatcgaca tagatatctt gggcgttgaa atgacctgcg atacgagctg agtcagcagt
     5101 aagggcaagc acatcgccat tgctcatgat aaagatattg tccttctcaa caccagtatc
     5161 cactgctagt ccagcgtgga ctttttgcat gcggtattca ccgtggacag gcatgaagta
     5221 ttttggctta atcaagcaga gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt
     5281 atggatattg ttcactttac cgtggataac ttcgacacca gcttcagaaa tgatgttaat
     5341 cagcttgttg acgctagtag tgtttccagg gatgggacta gaagagaaga taacggtatc
     5401 acctggttgt aattgtactt gacggtgggt tccgttggcg atacgagaga gggctgccat
     5461 aggctcaccc tgactacctg tacagaggat aagaacttct cctgcaggat aatctttgat
     5521 ttcatttggc tcgataaagg ttcccttagg agttttgatg tagccaagat cgattccgtt
     5581 gacaatggcc ttttccatag aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc
     5641 agcttctgtt gcctgctgga gacggaagat atttgaggca aaggatgcaa agatgatacg
     5701 tccttcaata ccttggataa tcttcataat ggactgacca acgacttttt cagagttggt
     5761 aaaggttggt acttccgcat ttgtcgagtc agacaggaga cagagcacgc cttcttcacc
     5821 aagcgcagcc atacgatgca agtccgcagg ttctccaact ggagtaaagt cgaacttaaa
     5881 gtcacccgta cagacgattt tcccttgagg agtatgaatg acaatcccca aaggctctgg
     5941 aatagagtga gtcgttctaa agaaagttgc cttgagattt ttaaaggtca actcggtgtt
     6001 gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg tgttcttcga gtttcccacg
     6061 gatcaaagcc aaggcaagcg gtccagcata aatagggaca tttgcttgct tgagtaggaa
     6121 cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc
     6181 gatattgtcc acgatgtaag agtagtcagg aatgacatag tcgataccaa gcaagtcatc
     6241 ttctgggaat ttaatcccag catcgacgat gataatctcg tcttggtatt caattccgta
     6301 agtgtttttc ccgatttctc ctagaccacc gatggcaaaa acgccgactt ctttaggttt
     6361 aagagtgtaa gccatattag aactccgtaa tttcgaaggc gccagtttct ttttcgtaat
     6421 cgagcaattt gtcagacaag agttcgatat attcgatatt gtactctggg cgattttctt
     6481 cgacaagttg gcgagcagcg atacggccct caagttctga gctggcatcg atgtctaggt
     6541 aaagcgcgcg tgttgtttcg cgacgtgggc tacgttcttt tgtttcttga taaaaaactt
     6601 tgtaaatcat atagttcctt tctatttaca ggtcagctta ttccaaactt ttagcagaga
     6661 attgcttgat ttcattccat tttttgtcta gattgacctt gattcgttac aattatttca
     6721 attataccac aaaatgaaaa attagtaaaa gacggaaacg agaaagttag gggacgattt
     6781 cttcggtaag cgtttgcaaa aataaagaaa atgtgttatg ttgataacgg aagtgaagtt
     6841 tattacttgt cataattcca tatagatttt aagtcaagga ggttgtccta tgtataactt
     6901 atttgctttt gctattggag ttcgtttgct agcttttatc gtttttgttg cttgcgttta
     6961 tggaggaaat cttctatttg ctaaactgga acgatgataa accaagttct tgtggaaaat
     7021 tacctttgtg actctctact cgctttttct cctcctcatg acctatgtcg tttggtttgt
     7081 attttacttt ggattaaatg cttagatgcc ctgcatatgt gaactgcacc ccaaaagtta
     7141 gacagaaaaa atctaacttt tggggtgttt tattatgaaa ttgagttatg aagataaagt
     7201 tcagatctat gaactaaga
//
LOCUS       DAVFJR010000069         6853 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVFJR010000069 DAVFJR010000000
VERSION     DAVFJR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.070"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VU722_002076"
     CDS             complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VU722_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU1772965.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
     gene            complement(587..763)
                     /gene="secE"
                     /locus_tag="VU722_002077"
     CDS             complement(587..763)
                     /gene="secE"
                     /locus_tag="VU722_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU1772966.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VU722_002078"
     CDS             complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VU722_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1772967.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(978..3173)
                     /locus_tag="VU722_002079"
     CDS             complement(978..3173)
                     /locus_tag="VU722_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU1772968.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3299..4135
                     /locus_tag="VU722_002080"
     CDS             3299..4135
                     /locus_tag="VU722_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1772969.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVSQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VU722_002081"
     CDS             complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VU722_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU1772970.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(5387..6352)
                     /locus_tag="VU722_002082"
     CDS             complement(5387..6352)
                     /locus_tag="VU722_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU1772971.1"
                     /translation="MNMSNITIEDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDK
                     VLAGSLYTDTNEQGLTIPSSLLKNWNEQTGRNLTANDLIGKSVSASIVESAAEASKIA
                     QFQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVT
                     EELQKNKKYTVLSQQKVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQR
                     SKEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSI
                     TKVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(6413..>6853)
                     /locus_tag="VU722_002083"
     CDS             complement(6413..>6853)
                     /locus_tag="VU722_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772972.1"
                     /translation="ETGFDTYFYREYGRSLKGQLIRGKVSGRRYQRISLVAGLTNGEL
                     IAPMTYEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2051 a         1477 c         1189 g         2136 t
ORIGIN      
        1 attctgcgat ttggtttagg tttacttctg caactgtgtc attaccaaac atagagataa
       61 tcattttcac tttgttatta tcaatttctg taatcttacc agtgtagtct gcaaaagcac
      121 catcaataat acgtacagtt tgaccaatct caacatcgaa atcaaattct tgaacagttt
      181 gtcccataga taccaaaatg tcacgaattt cttgttccaa taatggagtt ggttttgatc
      241 tgttcccgtg tgatccgaca aatcctgtaa catttggtgt gtttcgaaca acaaaccaag
      301 cttcatctgt catgaccatt tctacaagaa cataacctgg aaaacgattt tcttctactt
      361 cttttctctt tccatttttt tcaacttgca ctgtttgtgt tggaatttca acgcgtagaa
      421 tattatccaa catattgtag gtttgtgcac gttgtaatag attttctttc accttatttt
      481 cataaccaga ataagtttgt aaaacaaacc accctttatc aaaactatcc atgatatttc
      541 ctttcataaa tagaagattt ctagtgtaat taactccact aatcttctaa aaaatgttaa
      601 taaatcgaat caaacctgaa acaatcaact ggtcaaaaat gtaaataatt actacaaaga
      661 aagctgtgta ttccatgata gaacgaaaat ctctccagct ttccttgcga gttggccatg
      721 ttgtgtcttt aagaagtcta aaaatatctc caataaaacg catcgctctc tcctatctcg
      781 tttctctgtg tgtagtgtac ttgccacaat gcttacaaaa tttatttact tctagtcgtg
      841 taggcttggg gtttccgctg atcttgattg aatagtttct cgaaccacaa accgcacaag
      901 ctaggcttgc tttttttagt gccataacgc ctccatctta tccattataa caagaaagct
      961 aggctttgac aagcatctta gcgaaataga ttgactatcg aatcccatat tgtttgagcc
     1021 ttttccttaa tcttcgcatc tgagatagcc cggctagcct catctactag actttgcgca
     1081 cgccctcgaa tatcagacaa attatcatct gtctggctat tatcattggt ttgtacttgt
     1141 ctttttgtat tggctggtgc aattccattt tgcttataag cattttcaac cgtaaaggta
     1201 cttcctggcg tataaggtaa aatggtattg gcaatgtttc taaagacatg agctgcaccg
     1261 tttgaagtag agccagctag atagtgattt tcatcagtgg tcggaaagcc aagccagtgg
     1321 ctaatcacta catccggagt ataaccaatt acccactggt cacttgtgta ctccggatta
     1381 aaaactgctt cagttgttcc agtcttccct gccataatat agtctgcagg cgatgaacta
     1441 ataccggtac cgttggtgaa agtccccaac atcatactgg tcatcttgtc agctacagac
     1501 ttatcaatca cccgtttttg tgaattttta tgattcgcaa taacttgtcc actagcattt
     1561 tcaattctac taataaaatg agcttcaggc attaaacctt catttgcaaa ggcagcgtat
     1621 gcttgagcca tttgaagagg gttggtttca acaccgcttc ccaaggcgac accaagaaca
     1681 cggtcgacct tttccatgtt gagtccgaat ttttcgcctg cctcaaaagc cttgtcgaca
     1741 cccaaatcat taacagtggc aacagcaggt agattaagcg attctgccaa ggcttgatac
     1801 ataggaactt ctcgactcgt tttgatccct gcatagttat caaccttata gctgtcatac
     1861 tgcatggtat ggttatccaa ctgcttattc aaagcccagc ctgcttcaac tgctggcgta
     1921 taaacaacta aaggcttaat tgtagaacca ggactacgct ttgattgggt tgcatagttg
     1981 aaattccgga atccagtttt atcattgtca gcaacttgac cgacaactcc acgaactccc
     2041 cctgttttcg gttcgagagc tacacttcct gattgagcaa acgttccatc ctctgccctc
     2101 ggaaatagcg atgtgttttc ataaacaatc tgcatatttg cttggtagtt ttggtccagc
     2161 tctgtgtaaa tgcggtagcc attattgaca atctcttcct ctgttagatt atacttggaa
     2221 acagcttcat taaccaccgc atcaaaataa gaggggtaac ggtaatctga gatttttcct
     2281 tcatacttat cgtgcaattg cgaagtcata tcaacttcag cagcttcggt ttcttggttt
     2341 ttatcaatat atcctgctgc aaccatattc tgcaagacag tatcgcgccg attagtagaa
     2401 tcttctacgg aattcaaggg attatacagt tccggcccct tgagcatccc tgccagagtc
     2461 gcagcttgat ccagactcac ttctgatgca gaaactccaa agtatttctt actcgcatct
     2521 tctacacccc acacaccatt tccaaaataa gcgttgttaa ggtacatggt tagaatttgc
     2581 tccttactat attttttgct taattctaag gcaaggaaaa attctttcgc ttttctctca
     2641 acagtttgat cttgtgataa ataggcgttt ttagccagct gttgggtaat ggtagagcca
     2701 ccacctgaac gtccagcagt gacaatagcc aagaagaaac ggccatagtt aatcccgtca
     2761 tttttataga aagaacggtc ttctgtcgca ataacagcat tctgcaagtt tttactgata
     2821 tcagtcagct caacataggt tcccttttga ccagacaagg caccagcctc tttttcttca
     2881 cgatcaaaaa taagagtccg agttttcaag gcattttgca aatcattgac attggtcgac
     2941 ttagctacag caaacaaata gattccaact agcaagcctg cactcaaacc tagtataagg
     3001 ataatctttg ttagatgata acgacgccag aattttcgaa tcggacctac ttgggctaat
     3061 ttttttcgat cactacgaga gcgacgtaag atagtagaat cagagtcctc tagttcactt
     3121 gtttcttttt taaaaagaga aagaaatttc tcaaataatt tatctaattt catgcgttta
     3181 ttttatcatc ttcatcatag gaagacaaga atttagctat ttcctatcca aatagggctt
     3241 tttttgttac aatatctgta tgcaattcac atttacatta cccgcctctc tacctcaaat
     3301 gacggtaaag caattacttg aggaacaact cctcatccct agaaaaatcc gtcatttttt
     3361 gagaatcaag aaacatattt tgataaatca agaagaagtc cactggaacg aaatcgtaaa
     3421 tcctggagat gtttgccagt tgacttttga cgaggaagat tatccccaaa agacgatccc
     3481 ttggggcaac ccagacttag tgcaggaagt ttatcaagat caatacttga ttattgtaaa
     3541 caaaccagag gggatgaaaa cgcatggtaa tcaaccaaac gaaattgccc ttcttaacca
     3601 tgtcagtacc tatgttagcc aaacctgcta tgtcgttcat cgtctggaca tggaaaccag
     3661 tggcttagtt ctctttgcca aaaatccttt tatcctgccc attctcaatc gcttattgga
     3721 gaaaaaagag atttctagag aatattgggc tctagttgat ggaaatatca acagaaaaga
     3781 acttgttttc agagacaaaa ttggacgtga tcgccatgat cgtagaaaaa gaatagttga
     3841 tgcaaaaaat gggcaatatg ctgaaacgca tgtaagcaga ttaaagcaat tctcaaacaa
     3901 gacttccttg gctcattgca agctaaagac agggcgaacc catcagattc gtgtgcacct
     3961 tttgcatcat aatcttccta tcctgggaga ccctctctat aatagtaaat caaagacaag
     4021 ccggcttatg cttcatgcct tccgactttc ctttacccac ccacttactt tagagaagct
     4081 aactttcact accctttcaa atacatttga aaaagaatta aaaaagaatg gatgatcgtg
     4141 tcatccattt ttccgtataa aaaaacaaga ccacaaagcc ttgctttcta tcaactcaag
     4201 aattatttag caatttttgc gaagtattca agagtacgaa caagttgtgc agtgtatgac
     4261 atttcgttgt cgtaccatga tacaacttta accaattgtt taccgtcaac gtcaagaact
     4321 ttagtttgag ttgcgtcaaa caatgaaccg taagacatac ctacgatatc tgaagatacg
     4381 attggatctt ctgtgtaacc gtatgattcg tttgaagctg ctttcatagc tgcgttcact
     4441 tcatcaacag taacgttctt ttcaagaact gctaccaatt cagtaactga tccagttgga
     4501 gttggaacgc gttgtgcaga tccgtcaagt ttaccattca attctgggat tacaagaccg
     4561 atagcttttg cagcaccagt tgagttagga acgatgtttg cagcaccagc gcgagcacgg
     4621 cgaaggtcac caccacggtg tggtccgtca aggatcattt ggtcaccagt gtaagcgtgg
     4681 atagtagtca tcaatccttc aacaacacca aagttgtctt gaagagcttt agccattgga
     4741 gccaagcagt ttgtagtaca tgaagcacct gagataactg tttcagtacc gtcaagaacg
     4801 tcgtggttag tgttgaatac aactgtttta acgtcgtttc caccaggagc agtgataaca
     4861 acttttttag ctccaccttt aaggtgtttt tcagctgctt ctttcttagc aaagaaacca
     4921 gtagcttcaa gaacgatttc tacaccgtca gtagcccagt cgatttgttc tggatcacgt
     4981 tcagcagaaa ctttgatgaa tttaccgtta acttcaaatc caccttcttt aacttcaaca
     5041 gtaccgtcga aacgaccttg agttgtgtcg tatttcaaca agtgtgcaag cataactgga
     5101 tctgtaaggt cgttgatgcg tgtaacttca acaccttcta cgttttggat acgacggaaa
     5161 gcaagacgac cgatacgtcc gaaaccgtta ataccaactt taactaccat tagtgatttc
     5221 ctccttatga aaatcatgaa atttttattg tgaaaagagt aacttgaatc actacaaatc
     5281 acctttcaac aaacctatta tacaactatt tgagttgaat tgcaagtatg gccattgttt
     5341 ttctatgtta gtttcttttt aagactgtaa atcaaggaat cccttactat tcatagcgta
     5401 acgattctac aggatccatt ttactaatct tacgcgccgg gaagtaggct gagacataac
     5461 caagtaatag agcgaaaact agagttccta aaacagataa aagatttaat tcaaaaacct
     5521 tagtgatgga tgggtaaaag tgacttacaa tcgcattcgc caaacttccc accccttgtg
     5581 caaccaaaaa tgccagcagc aaggcgatgc ctacaatcca gatagcctcg taaataaaaa
     5641 ttcctttgac atcacgattc tgataaccaa ctgctttcat gacacctatt tccttggaac
     5701 gttgcatgat attgatgtaa ataatgatac caatcataac cgctgctacc acaatagctt
     5761 gtgatgaaag cacaatcaat aatccctgaa taacacgaat aaagataatc acaatatcaa
     5821 gaactttttg ttgagaaagc acagtatact tcttattttt ctgtaattct tctgttacta
     5881 cttttgtctg tgatggatct ttgagttcca agataaaata agatacagct ttcgtaaatc
     5941 cagcctcttt caaaatcgtt tccatttgat gagacagcat gaaactgttg ctgtcctcca
     6001 tgtcatcttc atcattgatt acacgtacaa tcttcgtttg aaattgagca atcttactag
     6061 cttcggcagc actttctaca atgctggctg agactgattt accaataaga tcattagctg
     6121 tcaaatttct tcctgtctgt tcattccaat tttttagtaa actgcttgga atcgttaatc
     6181 cctgttcatt tgtatcagta tagagggatc cagccaacac tttgtccgtc tcattattac
     6241 taacagagat acttgtatca tcataaagac tcactacttg agcataagaa ggcatcgttt
     6301 gactcagatc catttcttgc ccatcttcta tagtaatatt tgacatgttc atcccaaaag
     6361 gactctccaa ataattaata gcttctttcc caactgtatc cgtgaactat agtcaattga
     6421 aacaagaaca agagaaaaga gcctcgtaaa aggtattgca acttggtaat acctttttga
     6481 ggttcttttt gatatgagcc catgttttct caataggatt gtactcaggt gagtagggag
     6541 gaagaggtaa aagtttatgc ccaaactctt cgcataaaag ttctagcttc cccattctat
     6601 ggaatcttac attatccata ataataaccg atggtgtggt taatgttggt aagagaaaat
     6661 tctgaaacca agcttcaaaa aagtcgctcg tcatcgtctc ttcgtaagtc attggagcga
     6721 ttaattcacc atttgttaga cctgcaacca aagaaatcct ctgatatctt cttccagata
     6781 ctttgcctct tattaactga ccttttaatg agcgaccata ttctcgataa aaataagtat
     6841 cgaatcctgt ttc
//
LOCUS       DAVFJR010000070         6352 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVFJR010000070 DAVFJR010000000
VERSION     DAVFJR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.071"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..261)
                     /locus_tag="VU722_002084"
     CDS             complement(<1..261)
                     /locus_tag="VU722_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772973.1"
                     /translation="MILRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQ"
     gene            complement(920..1804)
                     /locus_tag="VU722_002085"
     CDS             complement(920..1804)
                     /locus_tag="VU722_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU1772974.1"
                     /translation="MMEKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKQIKECL
                     HQMILDQEQIQEIILSLWENSVVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(1808..2194)
                     /locus_tag="VU722_002086"
     CDS             complement(1808..2194)
                     /locus_tag="VU722_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU1772975.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEV"
     gene            complement(2187..3530)
                     /locus_tag="VU722_002087"
     CDS             complement(2187..3530)
                     /locus_tag="VU722_002087"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU1772976.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNIKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWSNSGNYDASVKQALADMLEVFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3612..4496)
                     /locus_tag="VU722_002088"
     CDS             complement(3612..4496)
                     /locus_tag="VU722_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772977.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRLYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPKRGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4508..5125)
                     /gene="cysE"
                     /locus_tag="VU722_002089"
     CDS             complement(4508..5125)
                     /gene="cysE"
                     /locus_tag="VU722_002089"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU1772978.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5141..>6352)
                     /gene="pnp"
                     /locus_tag="VU722_002090"
     CDS             complement(5141..>6352)
                     /gene="pnp"
                     /locus_tag="VU722_002090"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU1772979.1"
                     /translation="DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKR
                     FMHHYNFPQYSVGETGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLE
                     SNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDM
                     DFKVAGTRDGITALQMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELA
                     PTAPKIDTIKIDVDKIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINR
                     AKEIIAGLVREAKVDEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDL
                     VEIGDEVDVKVIKIDEKGRIDASMKALLPRSPKPEHDEKGEKSERPHRPRHQKDHKPK
                     KEFTETPKDSE"
BASE COUNT         1829 a         1497 c         1194 g         1832 t
ORIGIN      
        1 ctgatgatgc acctgaatct caatgattac ttgagtacca ttatccaact ccgccaagac
       61 gtctatacta gtgtaaaaat cttgagctga gtaaggcata gaaggcaaaa catgaatgtt
      121 acttccctcc aaaatagtca cattttttgc tggcaagtcc agcatatcgc gaataaattg
      181 acaagtgatt tccggattgc taaagatttt cttagcaact aagtcattgg ttgggctgat
      241 gcccggatgt ctgagaatca tccttctcct ccttctatta taccatagtt ttaaatctaa
      301 ttttgctaga ttctatggtt ctatctattt attcgaaaaa gaaaggagaa agttaaaaat
      361 ttttagactt cacaggttga aatttacata aaaaagcagc tgattctttt tttgattcta
      421 ccatatttct agcgattact cctataaata ggatacatca cagtttctag taaaaaagga
      481 cgctgaaaag caaacaaaac ccagtattag gaagagttaa atcttatctg aaaatgacta
      541 gctctcaagc tatagttttg tgtctaaata taagtatcac taggaaaaac tccgtaagta
      601 aacacaccga aattggatgt tcctactatg cgaaaacctc tttaaactac gtcaacttta
      661 ccttacctac agcttcaaaa ggacgttttg agtcatctgc tggtcgattt attcattgat
      721 tttcaatctt ctaatactaa acaaaaatca aacaactata gtgaaataac ataaaattta
      781 catgaataga ttagggaaat caaagcaagt tctaggaatg ttttagcagt caccgtatac
      841 tttcccagcc tcaatccact ataactctac acataaaaat ggagaagatg gccatcctct
      901 tctccaaata ttaacttctt tacaaaccaa ctatagttga caaagaacct aaaatcaatt
      961 gataacacaa ggtcaggtcg gtcaactctt tcaactgaag ccctgtcaac tcttcccatt
     1021 tatcaatctt gtattggaga gaattgcggt gcagatatag ttgctgggct gttttagtga
     1081 gaacaacact attttcccaa agagagagaa tgatttcctg aatctgttct tgatccaaaa
     1141 tcatctggtg tagacattcc ttgatttgct tcaagtccac gagtctttct cccatactcc
     1201 aaagatagag ctgagaaaaa gtatgaacac cttggtgacc ctgacgccac catgtcttga
     1261 acaaatcccg ctcagctttg attaagtctg atagggcttg atgccccgtc tgagaccaaa
     1321 cctgacccaa catgatagaa agacgaagtc caaagtcata ctcaaccgct tcaatcgtat
     1381 cacttaaaat atctcttaca gaagtgtatt tgtcttgttg aagcacgaaa acataatcct
     1441 gagctccgac ctgtagcact gtctgacaat tcggaaaaag agtccgcatc atatctagcc
     1501 aagaagccag attttcctgc tgaaaataag aaagatggca ataaactaac tgaatctttt
     1561 taaaaacttg cggtgcctgt cccttgcctt caaccagata ggaataccaa gggtttagcg
     1621 aacgagcctg ctcctgctgg gtcaaaaggg caaccaactg cttttcacgc tcgctgagcc
     1681 cagcttcctc cagcaaaatc cactgctgag aagctaaagg gagcgtgaga tagccctctt
     1741 tctctactgg ttggtctgaa atccgagcct caggaaacca gtcttgtagt tctttttcca
     1801 tcatgtccta gacctccact ttttggatgc accatgaaac caaactctca agacgttcca
     1861 gattctcagt catatggaga taacccatga ctgcttcaaa acctgtggac atacgataag
     1921 tcaccacatc tgcattttta gcctttgtgt gactattagt attgcggcca cgtttgtaga
     1981 tttcttcttc tttttccgtt agaacctgct cctccaacat gagagcaatc aggcgagcct
     2041 gagccttggc tgacacatac ttggttgctt cttgatggag tttattgggt ttggtcatac
     2101 ctttgaggat gaggtgacgg cgaatataca tagaatacac cgcatccccc tcaaaggcta
     2161 gcgcaatccc gttaatgaga ttgacatcaa tcacgtgtcc acctcactcc atccttggta
     2221 tcaaggagct taattccttg agtaaccaat tggtcacgga tttggtctgc tgtcgcaaag
     2281 tcacgattgg cacgcgcctc ttggcgtttt tgaatcaagt cttcaatctc tgcatccaaa
     2341 acttcctcaa caaagacaat tccaaaaact tctaacatat ccgcaagagc ttgcttgaca
     2401 cttgcatcat agttccctga gttgctccat ttggccattt caaagacaac tgtgataccg
     2461 ttggcagcat taaaatcttc atccatagct gctacaaact tatctttaaa gttttgtaac
     2521 tcttgggcat ccacatttcc tgtaaatggt tgttcgtaag tattcttcag atacttgaga
     2581 ttggtctcgg catcgcgaac tgccttttcc gtgaagttga taggcttacg gtagtgctgg
     2641 gtcgcaaaga agaaacgaag tacttgccca tcaagagttt taagggcatc gtgtaccgta
     2701 atgaagttac ccaaggactt agacattttg atattgtcga tattgacaaa gccattgtgc
     2761 atccagtagt tagcaaaagc cttgcctgtt ttagcttcag actgggcaat ttcattggtg
     2821 tggtgtggaa actctaggtc agctccacca ccgtggatat caatggtatc acctaaaatc
     2881 tctgtcgaca tgactgaaca ctcaatatgc caacccggac gtccaggtcc ccaaggacta
     2941 tcccaagaaa tctcacctgg tttggaagat ttccatagag caaaatctac aggattttcc
     3001 ttacgagccg tttcttcatc ggtacgacct gaagcaccta gatccaaatc ttccaaggtt
     3061 ttattagcta atttagcata gttgtgggat ttttctacac ggaaatagac atccccttga
     3121 ctctcatagg caaagccttt ctcgatcaag tcttccacaa aacggatgat gtctgccata
     3181 aactccacta cacgcggatg gcgagtcgca ggtttcacgc ctaaggccgt cacatcctca
     3241 cgaaaggcag cgatgtactt atccgcaacc tcctgaggcg tgataccttc ttccctggca
     3301 cggttgataa tcttatcatc cacatctgta aaattggaaa tataggcaac cttataccca
     3361 cggtactcaa aatagcgacg aatcgtatca aaagctaccg tcgaacgggc gtttcccacg
     3421 tggatatagt tgtacaccgt tggcccacaa acatacatct tgatcttgcc gtcctcaatc
     3481 gggacaaatt ctcgcaaatc acgagacatg gtgtcataga ttttaatcat aaatcataat
     3541 caagaaagct gaaatccaag aacaattagt ttcatcacta aaagttcaag taaatttcag
     3601 tccgaatatc tctacacttc ggaatccctt gctcctttct cattcagata aaccacctga
     3661 gtctgtttga caaagccaat tttttcatac aaacgtttgg cacctacatt gctatcttcc
     3721 actgcaatct gaaattcctt gtcattttgc tcaattagtt ggttgacgag ggattttgct
     3781 aagtagcttc catagccttt cccacgttta ggttccgata ttgctaaacc gtagaagtaa
     3841 ttcgtattag tcgataaatc taccgtgcaa gtcccaataa cctgaccgtc ttttaacaaa
     3901 atatatagtc ggctttctgg atccttcaga gcttcagcga catatctatc cacaacttct
     3961 ctcgattcat gttcctctga aaatgcctga aattttaatt gactaatttg atcctgatac
     4021 gaactatctg ctaacaaaac ttcaagatgg gaaacatttg ctaacggata aagtcttcta
     4081 tccttaccta accaagtttc tgtctcttca tcctcgatta gtccccagtt actggcaaag
     4141 tcaggatgat tctctaaaaa aatacgttct gtctgaaaag tgactgatcg aatggggaaa
     4201 gaagctgttt ctctctcaaa actagtaaac aatgcacgcg caatcccctg acggcgatga
     4261 cctggatgaa ccagtatcgt cacttctaca tcttggtcat ctgcatagac agttaataaa
     4321 ccaacaagtt cgcctttttc ataataaagg aaaaaggcgg gcatgtttgg gtcaaaatta
     4381 agcatgttag agagataggg atcgcgatag gtaccgtcat agttttggca acagttaatt
     4441 acttttttcg cctcagatag ctcctcttgg cttaacttgt ttcttacttg aatcatatag
     4501 gtatcctcta caaaccagac gatctgtgac tggcatcttt agcctgctcg agtttattga
     4561 cataatactc tcgtttttct tcgacttcgt gaatgacagg ctcatctttc ttaccatgaa
     4621 gacggacaat cttggccgga ataccgacaa ccgtcacatc actaggtaca tctgctacga
     4681 caactgctgc agcaccgacc ttggcatttt caccaatttc cacaggtccg ataacttggg
     4741 catgggctga tatgagggct ccctttcgta cagtcggatg gcgtttgcca cagtctttcc
     4801 ctgttccccc aagagtcact ccgtgataga gaagaacgcc tttttcaaca atcgctgtct
     4861 ctccaatcac cagaccagaa ccatggtcaa taaagacacc tgaatcaatc tgggctcctg
     4921 gatgaatctc aatctgagtc caaaagcgcc aaaactgact gtgcatacga gctaagagtt
     4981 tgaagccgtg cttccagaga aaatgcgaga gacggtgggc cgccaaggcc ttgacacctg
     5041 gataagtcag caaaacctcc aaagtggtgc gggccgctgg atcattttct tttacgatat
     5101 caatggtttc gcgccaccac cccatacatt tctccttttc ttattctgaa tcttttggtg
     5161 tttctgtaaa ttctttctta ggtttgtgat ccttttgatg acgtgggcgg tgagggcgct
     5221 cagacttttc acctttttca tcatgctcag gttttggcga acgaggtaga agagccttca
     5281 tagaggcatc gatacggcct ttttcatcaa tcttgataac cttaacatca acttcatccc
     5341 cgatttctac caaatcctct acacgattgg tacgagtcca agccatctca gagatatgaa
     5401 caagggcatc tgtcttatca aagaggttaa caaaggcacc aaatttctcg atacgaacga
     5461 ctttagcacg gtaaacttca tccactttgg cttcacgaac caaaccagca ataatttctt
     5521 tggcacggtt aatagcatct tggtcactag agtagataga cacatttcct tcttcgtcta
     5581 tatcaatctt aacacctgtt tcagcgataa tcttgtcgat ggtttctcca cccttaccga
     5641 tgacaatctt aatcttgtcc acatcaatct tgatcgtatc aattttcgga gcagttggag
     5701 ccaattctgg acgaacttct ggaatggttg cttcaatgac atcaaggatt tcaaaacgcg
     5761 ctttcttggc ttgagcaaga gcctccgtca agatttctgc agtaatccct tgaatcttga
     5821 tatccatttg aagggctgta atcccatcac gagtacctgc aaccttgaag tccatatctc
     5881 caaagtgatc ttccaaacct tggatatctg tcaatactgt gtagttattt ccatctgaga
     5941 taagtcccat agcaatacca gctactggcg ccttgattgg cacaccacca gccataaggg
     6001 caagagttcc cgcacagata gaagcttgag atgaagaacc gtttgattcc aaaacttctg
     6061 ctactagacg gatagcgtat gggaattctt ccaagcttgg taagacttga gcaagagcac
     6121 gctcaccaag agcaccgtga ccgatttcac gacgacctgg cgcaccgtaa cgacctgttt
     6181 cccctacaga atattgaggg aagttatagt ggtgcataaa gcgtttcttg tactctggat
     6241 ccaaaccatc aatgatttga gtttctccca tcggagccaa ggtcaagact gaaagagctt
     6301 gagtttgccc acgagtaaag agacctgaac catgtacacg aggaaggaag tc
//
LOCUS       DAVFJR010000071         5476 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVFJR010000071 DAVFJR010000000
VERSION     DAVFJR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.072"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            71..370
                     /locus_tag="VU722_002091"
     CDS             71..370
                     /locus_tag="VU722_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU1772980.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            367..684
                     /locus_tag="VU722_002092"
     CDS             367..684
                     /locus_tag="VU722_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU1772981.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRDIYPALPEIEE
                     TNPEFTFIRMGRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            700..1326
                     /locus_tag="VU722_002093"
     CDS             700..1326
                     /locus_tag="VU722_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU1772982.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMIPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            1368..2129
                     /locus_tag="VU722_002094"
     CDS             1368..2129
                     /locus_tag="VU722_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU1772983.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTRQPRRVQITDMTIMANQQATGFMIHKK"
     gene            2207..2602
                     /locus_tag="VU722_002095"
     CDS             2207..2602
                     /locus_tag="VU722_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU1772984.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRPRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            2872..3156
                     /gene="groES"
                     /locus_tag="VU722_002096"
     CDS             2872..3156
                     /gene="groES"
                     /locus_tag="VU722_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU1772985.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            3172..4794
                     /gene="groL"
                     /locus_tag="VU722_002097"
     CDS             3172..4794
                     /gene="groL"
                     /locus_tag="VU722_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU1772986.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGSATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4894..>5476)
                     /locus_tag="VU722_002098"
     CDS             complement(4894..>5476)
                     /locus_tag="VU722_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1772987.1"
                     /translation="NAKIVLDRFYIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYW
                     KLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYHLYQLLLFHFQNKE
                     PEKFFGFIEDNLKQVHPLFQTIFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKR
                     NAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         1655 a         1007 c         1307 g         1507 t
ORIGIN      
        1 taaaggaaga ggctttttac ttgcttttct gctgcttcct catttgtctt gaagcctttt
       61 ttgtgttaaa atgaatggta tgaaagctaa aaaaatgtgg atggcaggct tggctctgct
      121 aggtatcgga agccttgctc ttgctacgaa aaaagttgca gatgaccgta agctcatgaa
      181 gactcaggaa gagttgacag agattgtgcg agaccatttt tccgacatgg gggaaattgc
      241 gaccctttat gttcaagttt acgaaagcag tctggagagc ttggttggtg gcgtcatttt
      301 tgaggatggc cgtcattata cctttgtcta tgaaaatgaa gacctagtct atgaggagga
      361 agtcttatga tacagccagc aagtttagaa gaattagcat ctttagtgga aaaagcgggc
      421 aagaaggtct tcctttttgt ggcagactgg tgtggcgatt gtcgtgatat ttatcctgcc
      481 ttaccagaga ttgaggagac caatccagag ttcaccttta ttcgaatggg ccgagatcag
      541 tatatggatt tggccaaact ctgggatgtt tacggaattc ctagccttgt tgttctagaa
      601 aaggacaagg aaatcggtcg ttttgtcaat cgcgaccgta aaagtaagga gcaaattaac
      661 gattttttag caggattgaa ataggagaaa aaggaaacaa tgatttttac atataacaaa
      721 gaacatgtcg gtgatgtcct tatggtcatc gtgaaaaata gcggagatgc caaactgaat
      781 gtggaacgca aaggcaaggt agcccgtgtt ttcctcaaag aaaatgggga aacagtagct
      841 tggaacattt ttgaggtttc gagcttgttt gaaattgcag agcgaggtca agtcttttta
      901 tcagatgagc aagtcgcttg tttgaaccaa gaattacagg cggaaggttt tacagaagaa
      961 attgtcaatg acaaggaacc taagtttgtt gttggtgaaa ttgttgagat ggtagcccat
     1021 ccagatagtg accacctcaa catctgccaa gttgcagtcg caagtgataa gactgtacaa
     1081 attgttgcag gagctcccaa tgcgcgtgtg gggttgaaaa ccattgtcgc gcttcctgga
     1141 gctatgatac caaaagggaa tctcattttc ccaggtgaac ttcgtggtga aaagagtttt
     1201 ggtatgatgt gcagtcctcg tgaattgcat ctgccaaatg ctccacaaaa acgtggggtg
     1261 cttgaattat cagaagacca agttgtcgga acaccatttg actcagctaa acactggact
     1321 gcctaagaag ttgttaatat ctgatagacc agctagaagg aaataagatg gcaaaaaatg
     1381 ttgtgattac aggagcgaca tcaggaatcg gtgaagcgat tgcgcgtgct tatctagagc
     1441 agggtgagga tgtcgttcta acaggacgac ggatagacag actagaagct cttaaggcgg
     1501 agtttgcaga aacttttcca aatcaaacag tttggacttt tccactagat gtgacggata
     1561 tggtcatggt gaagactgtt tgctctgata ttctagaaac gatagggagg attgatatct
     1621 tggtcaacaa cgccggactg gctcttggct tagctcccta tcaagactat gaagagttgg
     1681 atatgctgac catgttggat accaatgtca aaggtttgat ggcagtcact cgctgtttct
     1741 tgccagcaat ggtaaaagcc aatcaaggtc atattatcaa tatggggtca accgcaggaa
     1801 tttatgccta tgctggtgca gctgtttact cagccaccaa ggcggcagtt aagacctttt
     1861 cagatggact gcgaattgat accatcgcaa cggatatcaa ggtgacaacc attcagcctg
     1921 ggattgtcga aacagatttc tcaactgttc gttttcatgg tgataaagag cgggctgcgt
     1981 ccgtttacca aggaatagaa gccttgcaag ctcaggatat tgcagacaca gtagtctatg
     2041 tgaccagaca gcctcgccgt gttcagatta cagatatgac cattatggct aatcaacagg
     2101 cgacaggttt catgattcat aaaaaataag aaatttcctc gaaaagttac aaatttctgt
     2161 aacttttttt gatttcctac gaatagataa gtaggaggaa gaaaatatgt ataataaagt
     2221 tatcatgatt gggcgtttaa cgtctacacc agaattgcac aaaaccaaca atgacaagtc
     2281 ggtagcgcga gcaactatcg ctgtcaaccg tcgttacaaa gaccaaaacg gtgaacgtga
     2341 agctgatttt gtcaatatgg tcctatgggg cagactagca gaaactttgg caagctacgc
     2401 aaccaaaggt agtctcattt ccgttgatgg agaattgcgt ccccgtcgct ttgagaaaaa
     2461 tggtcagatg aactatgtaa ccgaagtcct tgtgacagga ttccaactct tagaaagtcg
     2521 tgctcaacgt gccatgcgtg aaaataatgc aggccaagat ttggcagatt tggtcttgga
     2581 agaggaagaa ttgccatttt aatactcttc gaaaatctct tcaaaccacg ttagctttat
     2641 ccacaacctc aaagcaatgc tttgagcaac ctgcggctag cttcctagtt tgctctttga
     2701 tttttattga gtataaacat taaaaagtct gagttggtct caggcttttt atcttgagaa
     2761 agtcagactt ttttcttgac tatttctgac caagtgatac aatagaatta tgaattagca
     2821 ctcaagttca aagagtgcta ataatatcta tctcattatg gaggaaatca gatgttgaaa
     2881 ccattagggg accgtgtggt cttaaaaata gaagaaaaag aacaaaccgt tgggggcttt
     2941 gtccttgcag gatcagccca agaaaaaacc aaaacagctc aagttgtggc tactggacaa
     3001 ggtgttcgta ccttgaacgg tgacttggtt gctccaagtg ttaaaactgg agatcgtgtc
     3061 ttagttgaag cccacgcagg tcttgatgtc aaagatggcg atgaaaagta catcatcgta
     3121 ggcgaagcta acattttggc aatcattgag gaatagaagg agaaagtaag tatgtcaaaa
     3181 gaaattaaat tttcatcaga tgcccgttca gccatggttc gtggtgtcga tatccttgca
     3241 gacactgtta aagtaacctt gggaccaaaa ggtcgcaatg tcgttcttga aaagtcattc
     3301 ggttcaccct tgattaccaa tgacggtgtg accattgcca aagaaatcga attggaagac
     3361 cattttgaaa atatgggtgc taagttagta tcagaagtag cttctaaaac caatgatatc
     3421 gcaggtgacg ggactacgac tgcaacagtc ttgacccaag ctatcgtccg tgaaggaatc
     3481 aaaaacgtca cagcaggtgc aaatccaatc ggtattcgtc gtgggattga aacagcagtt
     3541 gccgcagcag ttgaagcttt gaaaaacaac gccatccctg ttgccaataa agaagctatc
     3601 gctcaagttg cagccgtatc ttctcgttct gaaaaagttg gtgagtacat ctctgaagca
     3661 atggaaaaag ttggcaaaga cggtgtcatc accatcgaag agtcacgtgg tatggaaaca
     3721 gagcttgaag tcgtagaagg aatgcagttt gaccgtggtt acctttcaca gtacatggtg
     3781 acagatagcg aaaaaatggt ggctgacctt gaaaatccgt acattttgat tacagacaag
     3841 aaaatttcca atatccaaga aatcttgcca cttttggaaa gcattctcca aagcaatcgt
     3901 ccactcttga ttattgcgga tgatgtggat ggcgaggctc ttccaactct tgttttgaac
     3961 aagattcgtg gaaccttcaa cgtagtagca gtcaaggcac ctggttttgg tgaccgtcgc
     4021 aaagctatgc ttgaagatat cgccatctta acaggcggaa cagttatcac agaagacctt
     4081 ggtcttgagt tgaaagatgc gacaattgaa gctcttggtc aagcagcgag agtgaccgtg
     4141 gacaaagata gcacggttat tgtagaaggt gcaggaaatc ctgaagcgat ttctcaccgt
     4201 gttgcggtta tcaagtctca aatcgaaact acaacttctg aatttgaccg tgaaaaattg
     4261 caagaacgct tggccaaatt gtcaggtggt gtagcggtta ttaaggtcgg atccgcaact
     4321 gaaactgagt tgaaagaaat gaaactccgc attgaagatg ccctcaacgc tactcgtgca
     4381 gctgttgaag aaggtattgt tgcaggtggt ggaacagctc ttgccaatgt gattccagct
     4441 gttgctacct tggaattgac aggagatgaa gcaacaggac gtaatattgt tctccgtgct
     4501 ttggaagaac ccgttcgtca aattgctcac aatgcaggat ttgaaggatc tatcgttatc
     4561 gatcgtttga aaaatgctga gcttggtata ggattcaacg cagcaactgg cgagtgggtt
     4621 aacatgattg atcaaggtat cattgatcca gttaaagtga gtcgttcagc cctacaaaat
     4681 gcagcatctg tagccagctt gattttgaca acagaagcag tcgtagccaa taaaccagaa
     4741 ccagtagccc cagctccagc aatggatcca agtatgatgg gcgggatgat gtaagctttc
     4801 tatagaaaac aacttataaa aaacacaaaa ggagggaatg actaaccctt ctttttatag
     4861 gctctttgtc aactgtagtg ggttgaaaaa aagctaagct tgagaaagga caaatttcgt
     4921 cctttctttt ttgatattca gggcgataaa aatccgtttt ttgaagtttt caaagttccg
     4981 aaaaccaaag gcattgcgct tgataagttt gatgagatta ttggttgctt ccagtttggc
     5041 attagaatag tgtagttgaa gggcgttgac aatcttctct ttatctttga ggaaggtttt
     5101 aaagatagtc tgaaaaagag gatgaacctg ctttagattg tcctcaatga atccgaaaaa
     5161 tttctccggt tccttattct gaaagtgaaa cagcaagagt tgatagagat ggtagtggtg
     5221 tttcaagtct tctgaatagc tcaaaagctt gtttaaaatc tctttattgg ttaagtgcat
     5281 acgaaaagta ggacgataaa atcgcttatc actcagttta cggctatcct gttgaatgag
     5341 tttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact gattcatgat
     5401 ttggacacgc acacgactca tagcacggct aagatgttgt acaatgtaaa agcgatcaag
     5461 aacgatttta gcattc
//
LOCUS       DAVFJR010000072         4932 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVFJR010000072 DAVFJR010000000
VERSION     DAVFJR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.073"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            85..374
                     /locus_tag="VU722_002099"
                     /pseudo
     CDS             85..374
                     /locus_tag="VU722_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            397..930
                     /locus_tag="VU722_002100"
     CDS             397..930
                     /locus_tag="VU722_002100"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU1772988.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPVLYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTELLPAL
                     KTPHVIVMGNTSFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            1270..1524
                     /locus_tag="VU722_002101"
     CDS             1270..1524
                     /locus_tag="VU722_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772989.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            1635..2144
                     /locus_tag="VU722_002102"
     CDS             1635..2144
                     /locus_tag="VU722_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1772990.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKPQNWQN"
     gene            2132..2741
                     /locus_tag="VU722_002103"
                     /pseudo
     CDS             2132..2741
                     /locus_tag="VU722_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818859.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            2699..3262
                     /locus_tag="VU722_002104"
     CDS             2699..3262
                     /locus_tag="VU722_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1772991.1"
                     /translation="MVPKTATSTETKIITRTIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVKSQEVTSDSSDKEITVRYDRL
                     STLEKPNPELPNQETPIPEPTPEPGTPKTETPVNPDPEVPTYETGKREELLNTGTEAN
                     ATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            3486..4355
                     /locus_tag="VU722_002105"
     CDS             3486..4355
                     /locus_tag="VU722_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU1772992.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQYMKQTAIQAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVVPIAA
                     AIAAVAVFKFLYL"
BASE COUNT         1688 a          873 c         1021 g         1350 t
ORIGIN      
        1 atttcagtaa aaaaaagtaa gtcttctaat aacaaaacat tgatatagtt gcttagtttt
       61 aaacaagcat attataataa agctatggca tatagtactg attttaaaca gcgagcatta
      121 gattacatca aagaggggca cagccatgtc gaggcagcca agttttttgg tgttggcgtc
      181 agaactctct tcacgtggga aaagaaagac gtaaacaagg acacatagag aggaaaaagc
      241 gagtcgtcaa aaaccgaaag attcctttag aggaattgaa agcctttgta gaggctcatc
      301 cagatgcttt tttacgggaa attgcggcac attttgattg tgctctgccc tccgtatggg
      361 cagctttaaa gtagattaag gtcactttaa aaaaagatga cgagctttaa ggaacaagag
      421 ccagagaaag tcgctgagtt tcttgatatt ttggataacc taaaagattt accagtccta
      481 tatattgatg aaacaggaat cgaccgctac ctctatcgtc cttatgcagg ggctcctaga
      541 ggggagaaag tctatgaaaa gattagcgga cgtcgttttg agcgaacttc aattgttgca
      601 ggacaagtag acggagagtt tatagctccc atgatttaca agaaaagcat gacaagcgat
      661 ttctttgtgg agtggttcaa aacagaactc ctgcctgctt tgaagacacc tcatgttatt
      721 gtcatgggca atactagttt tcatcccaag aacattttgg atgaactctg catccaagat
      781 aaacactttt tcttacctct accaccttat tcaccggatt tgaatcctat tgagcaagct
      841 tgggctatct tgaaaaagaa agtgacggat ttattaaggg aagttccaac tatttttgaa
      901 tgtttggaat gcttttttaa aactagatga ctataacggt tctaaaggaa cctatcgagt
      961 agtcattaaa actaaggata ctgctggtta agagaagacg gtatacgatc aaaccattca
     1021 ccgtgtagcc gaaatcgttc agaatgaaga cttgtataag gaaggtttga atgttgaact
     1081 tgcgcaccaa caaattaagg gattttttga agcagagttt aaaaatcgta ttaatggagt
     1141 tcttaatact aaaataaaaa atagtacatt aaatcgtgta aataaaaaaa ctatacacca
     1201 gagcaacaaa aactccatga tcaatttgaa gcagaagcaa cggaagatgc taaaaaacaa
     1261 ggcgatattg tgttgaatgt tgaccaggat ttcatgagca tatctaagtc taataaaagt
     1321 ggttcagact ggaagaaaac tttcacagtg aggacaacca ataggctagc aaatgacttg
     1381 aataatgtct tgaaacaggc tgataaagat actcctaata ccccaacttg gctaaactca
     1441 gctgcttcta aagctaaaga tgatgacaga gcatataaac tactgaagac tcttatacca
     1501 ggagaaaatt acctatcatg ttaaggataa tcagctagaa gtagaaacag ataaatacac
     1561 atatactgcc gctagaaatg gtagtaagga agttggtatt caagagtcag atatagcagc
     1621 aactctaagt gccgatgaat ataattctaa tcgccaaact tttgagagag aatacaaata
     1681 caaaagcaaa tgcccttaat aatggttggg ctagatctgg ttctgaagag ttcaaaaagt
     1741 tctcccactt tgtaggggta gacaaaggga ttgtgcgaac gaatgtactg actggtaaaa
     1801 aactatctga taagattagg aaagaagtgg gctctggaga tagcaaacta ggaaaaggcg
     1861 gctatttctc tactggggat gttctattag gaaaagatgt tgtttcttat accgtacaag
     1921 tattttcaga gaataatgaa agagtaggag taaacactca aagtcaccgt gttcagtata
     1981 atctcccaat tctagctgac ttttcagtca tccaagatac tgtggaacca tcacgaaccg
     2041 ttgttgaaaa aatcattcca aaactaaata ttcccgaaga agagaaaggg aaaataaccg
     2101 aagaaatcaa gaaaaagaaa aaacctcaga attggcagaa ctaatctcag aaaatgtgaa
     2161 agttcgctat gttgatgaac aagggcgttt gctatcattg aaaaatgata ctggaattgg
     2221 agaaaaagaa agtgacggaa cctacattac caataaaaaa acaactgatt ggtaccagct
     2281 ataatgtcac agataaaaaa ctcagtagca tgactactac tgacggaaaa tattatactt
     2341 ttaaagaagt agatacaaat tctgcaagtt taactgggaa tattgtaagc gaaggtagaa
     2401 cagtgacctt agtttataga gaaagcgaag cgccaaccac tgttacagta acagccaatt
     2461 actataaaga aggtagccaa gagaagttgg cagagtctgt tataaaagct gatttagcga
     2521 taggttctga gtataccaca gaatcaaaaa ctattgaagg gaaaacaaca actgaggata
     2581 aagaagaccg agttatcaca aggaaaacaa catacacctt ggtagcaact cctgcaaatg
     2641 cataccagaa gacggtgcaa cagttgacta ttactaccgt gagaatgttg aggaaacagt
     2701 ggttcccaaa acagcaacct ctactgagac gaagattata acgcgtacca ttcattacgt
     2761 tgataaagtt acgaaccaaa atgtaaaaga agatgttgtt caacctgtaa ccttaagccg
     2821 tacaaaaact gagaacaagg tcacaggagt tgtaacctac ggtgaatgga caacaggaaa
     2881 ctgggacgag gttgtatctg gtaagattga caagtacaaa gatccagata ttccaacagt
     2941 taaatcacaa gaagttacgt cagactctag tgataaagaa ataacggtaa ggtatgaccg
     3001 tttatcaaca ctagaaaaac caaacccaga actaccaaat caagagactc caataccaga
     3061 gccaactcca gaaccaggta ctccaaaaac tgaaactcca gtgaatccag acccagaagt
     3121 tccgacttat gagacaggta agagagagga attgctaaac acaggtacag aagctaatgc
     3181 taccttggct agtgctggta tcatgacctt gttagctggt ctaggattag gattcttcaa
     3241 gaaaaaagaa gatgaaaaat aatagatttt agaatctagg aacaaggaaa agctcacaga
     3301 tgtgggcttt tttcctggtt ttgagaacga ggtctttcgt gaagaataaa aacgcttata
     3361 aatctgttga actgggaaac tatgaatcct atttttttaa aaatatttcc agaaatcagt
     3421 tgctaaatag ggtaaaaatt gataaaatag ggaatatcta aaaaatttta aggagaatct
     3481 agcaaatgga tttcacatgg gcacttaagt atgccactga atttttggga actgccattt
     3541 tgatcattct tgggaatggt gcagttgcca acgttgaact taaaggtacg aaaggtcacc
     3601 aaagtggctg gatcgtcatc gctgttggtt atggtatggg ggttatgatc ccagccttga
     3661 tgtttggtaa cgtatctggg aaccacatca accctgcttt tactctaggg cttgcagtta
     3721 gcggtctttt cccttgggca caagtggtac cttacattat cgcgcaagtc ttgggggcta
     3781 tctttggtca agccttagtt gtggcaacat accgtccatt ctatttgaaa actgaaaacc
     3841 caaataacat cttgggaact ttctcaacta tttcaagtat tgaccatggt acaaaagaaa
     3901 gtcgctatgc agcaactgtc aatggtttga ttaatgagtt tgttggttca tttgttttgt
     3961 tctttgcagc tcttggtttg actaaaaact tctttggtgc tgaagtgctt caatacatga
     4021 aacaaacggc aatacaagca ggacaaacag ttgatttttc tgacttggct attaaagcac
     4081 aggtggctcc acacactgct tcaggacttt ctgtggctca cttggcactt ggattcctcg
     4141 ttatggcttt ggtaacatca cttggaggac ctacaggacc tgccttgaac ccagcccgtg
     4201 acttgggacc acgtctcctt catgctttcc ttccaaaatc agttcttggt gagcataaag
     4261 gcgattcaaa atggtggtat tcttgggtac cagtagtagt acctatcgca gcagcaattg
     4321 cggcagtagc tgtattcaaa ttcctttatc tctaagaaat agctccttta acatttgagt
     4381 gagcaccatc tataagtaag agaggatcag actggttctc tctttttgat tttttaggga
     4441 aatgaaagaa actctaaaca aactcctctc cagcagtggt ttagaagtct cagtgggcta
     4501 ttccagcttc aatgggctac tatagtgggt tgaagttgga atagtccccc cttctttctc
     4561 aaacattgtg aggaattgat ttaccttcct caacaaaatg ttcagtttct atttcatttt
     4621 gctataaaat aagcgattag gggggctatt cttcgaccta cattgactct gctgagtcct
     4681 atgattgtta tcgttttatc tgcaatttta tactcaatga aaatcaaagg gcaaactaag
     4741 aagctagccg caggttgttc aaaacacagt tttgaggttg tatagtagat tgaaactaga
     4801 ataatacaca tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt
     4861 gccctattct tgtttcattt tactatataa accagagact gtttacattt tcagcaagtg
     4921 agtggatgga ta
//
LOCUS       DAVFJR010000073         4802 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVFJR010000073 DAVFJR010000000
VERSION     DAVFJR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.074"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..960
                     /locus_tag="VU722_002106"
     CDS             <1..960
                     /locus_tag="VU722_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU1772993.1"
                     /translation="GYTIVEKTRGRVPESGECHPKKVKRTPIEGGERRKTEIVQELMT
                     EFSLALLLKVIKLARWTYYYHLKQLDKPDKDQELKAEIQSIFIEHKGNYTYRRVHLEL
                     RNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQ
                     CYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYE
                     NTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYE
                     KNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(1088..1291)
                     /locus_tag="VU722_002107"
     CDS             complement(1088..1291)
                     /locus_tag="VU722_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1772994.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1284..2366)
                     /locus_tag="VU722_002108"
     CDS             complement(1284..2366)
                     /locus_tag="VU722_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU1772995.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVPADQEPILFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLNKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2492..3274)
                     /locus_tag="VU722_002109"
     CDS             complement(2492..3274)
                     /locus_tag="VU722_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU1772996.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3274..4617)
                     /locus_tag="VU722_002110"
     CDS             complement(3274..4617)
                     /locus_tag="VU722_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU1772997.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGVDSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
BASE COUNT         1437 a          940 c         1062 g         1363 t
ORIGIN      
        1 gggtatacta ttgttgagaa aacaagaggg agagtacctg agagcggaga atgccatcct
       61 aaaaaagtta agagaactcc gattgaagga ggagaaagaa gaaagacaga aattgttcaa
      121 gaattaatga ctgaattttc gttagctctt cttctaaaag tcattaaact agctcgttgg
      181 acctactact atcacttgaa acagctagac aaaccagata aggaccaaga gcttaaagct
      241 gaaattcaat ccatttttat cgaacacaag ggaaattata cttatcgccg ggttcattta
      301 gaactaagaa atcgtggtta tctggtaaat cataaaagag ttcaaggctt gatgaaagta
      361 ctcaatttac aagctaagat gcgacagaaa cgaaaatatt cttctcataa aggagacgtt
      421 ggtaagaagg cagagaatct cattcaaggc caatttgaag gctctaaaac aatggaacag
      481 tgctacacag atgtgacaga atttgccatt ccagcaagta ctcaaaagct ttacttatca
      541 ccagttttag atggctttaa tagcgaaatt atcgcctata atctttcaac ttcacccaac
      601 ttagaacaag tacaaacaat gttggaacag gcattcacag agaagcacta cgagaatacg
      661 attctccata gtgaccaagg ctggcaatac caacacgatt cttatcatcg gttcctagag
      721 agtaagggaa ttcaagcatc catgtcacgc aagggcaaca gcccagacaa cggcatgatg
      781 gaatctttct ttggcatttt gaaatcggag atgttttatg gttatgagaa gaactttaga
      841 tctttagaaa accttgaaca agctattgtg gactacattg attactacaa caacaaacga
      901 attaaggtaa aactaaaagg acttagtcct gtgcagtaca gaactaaatc cttcggataa
      961 attaattgtc taactttttg gggggcagtt cattctacac ccactattat gcgttttatt
     1021 gtgggaagat tttcctcatt ttctagtgaa attgaacttt ttctaacatc ttttgataga
     1081 tgacttctta atcaattatc atttccattg ttgtttcttg gggtttcatc ccttgtcttt
     1141 gataaaagcg gagagcaccc tcgttatcat tccagacact tagggttaga ttattgcagc
     1201 caatttcttt agcataatag cagaaaaatg acaataaaat agcccctaga tattttgaaa
     1261 ggaaagcata ggggctatat agtttaatca aaataaagca aatctttgct ggtgcttgta
     1321 aagaggtcga agccatcctt ggtaacaaca ccgcagtctt caatacgaac accgacttta
     1381 ccagggatat agatacctgg ttcaacagag aagcacatgc cttcttcgat gaccatgtcg
     1441 tttccttcca tgatagatgg gaattcatgg acatccatac cgataccatg cccgagacgg
     1501 tggttgaagt actcaccata accagctttt tcgatgacct cacgggcagc gcggtccact
     1561 tcatgagcag tcacacctgg cttgataaag tcaagagcag cttgttgggc ttcaagagtc
     1621 aagttgtaaa tatctttctt gaattggtct ggtttgccga cagcgactgt acgagtcata
     1681 tctgacgcat agccattgac cagaacaccc aggtcaaaga ggagaagagc atcattttca
     1741 accttattag ctgctggaat gccgtgtgga ttcgcagcat tatcaccagt caagaccatg
     1801 gtatcaaagc tcatttcata accttcacgt ttcatggcaa agtcgatttg tgcgatgata
     1861 tctgtctcag tcttattaag agaaatattg tcaaaaccaa catgaacagc cttgtcagca
     1921 taaagacctg caaccatcat tttttgcact tcatcagctg atttgatgag gcgcatgcgt
     1981 tggatacgag gagtgaggtt gtcaaactca gcagtctcaa aaactgtttt caaaccatgg
     2041 tatttggtca agatgagatt gtcaaactca acagcgacac gtttgaagtc aagttgtgga
     2101 agagcatgtt tgattttttg ccatggattt tcagaatcga catagcccac tactgggaag
     2161 gaaacggtgc tacttgcacg ttctacttca agagctggga caaagaggat aggttcctga
     2221 tccgctggga caaagaggaa catttggcgt tcatggggat cactgtaaaa accagtgagg
     2281 taattgattg tgacggggtc agatacgaca gcgacgtcta gtttttctga ttcaagatat
     2341 gttaggattt gttgtaattt agacatatgc taccttcttt ctacccctct attttggcaa
     2401 aaaatgagag aaaatgcaag ggagaagggt aaaagaaaag acaaaaaact ccgacaagat
     2461 aacggagttc tttgatatca ttttcctttg tttaagaaaa gtcagccttg cttttgacgt
     2521 cactgtactc ttcagcgatt tcttggctga gaatatcctc ataggcaggg agttggatgt
     2581 cctgaccata tttcttcttg agggcagtag taactaggcg ataagccaga ttggcattac
     2641 gagagaggat aggcccgtgg aagtaggaac caaagacatt cttataatga accccttcac
     2701 cgaccttttc ttcgttgttt ccatttccat agacaacctg tcccagcggt ttttggtcat
     2761 cagagaggaa ggtacgacct tggtgatttt caaatccata gtaggtttca tcgaaatctt
     2821 cattgtgaat cttgatgtca ccgataaaac ggttattggt ctggttgagc gtgtagtgtc
     2881 ccatgacccc tagcccttcg atacgttttc ctgaagcttc aacataatat tgacccaata
     2941 gttggaaacc accgcagata gccagaacta caccgtcgtt ttggatgtag ttgtcaatgc
     3001 tctctttttt agcaggtagg tcgtctgcaa tgatactttg ttcaaagtct tgaccaccac
     3061 cgaaaaaggc gatgtcgtag tgattttcat caaagtcatc atggagagaa acgatgtcaa
     3121 cgatcacatg ggctcccagt ttttcagcca catacttgag catgaggatg tttccattgt
     3181 ccccgtaggt attcatgaga tttccgtaga ggtgggcaat gttgagctga taggggtaat
     3241 tgccatcttt tgaggaaagt gaagtataaa ccattagttc atctcctttc taacaatctg
     3301 acgactagcc agcagttcac gaaattccag catggcagta taagttgcca gaatataggc
     3361 atgcttgcag tcttgattct caatggtctt gagaacttgc tccagattac tcgtttcagt
     3421 gattttctca gctggatagc cagtcactcg gaggcgacga gcgatttcag aatgacgaac
     3481 accgccagcg ttgatttcag gaatgtccat gtcagtgatt tgttcaaagt ctgcatccca
     3541 gatccagcta gtgtcaattc catctgcata gttggcatta aggaggacag ataggctaaa
     3601 tggataaggt gctagtttga tcatttcgat agcttgggtt gcaccgactg gatttttaat
     3661 caagacaagg gtacattcct tgtcaccgat atgaaaggtt tcttggcgtc caaagacagc
     3721 acggctcttg tcaaatccct gtttgatgag ttgcgaatcg acacctagga aacgggcgat
     3781 ggccacagca gctagggcgt tatagatatt atagagcccg ccgatttgga taccgtattc
     3841 ttggccgtct atgacaaagc gagagcgatt gttggtcaac tcaaccagtt ttgtcaaacg
     3901 atagtcgaga tcaggacgtt tacatccaca accttcacag atataggcac ccaagtttgc
     3961 ataggtatta tgctcatatt tgaggatgcc ttggcagtca ggacagagaa tcccttcggt
     4021 attgtagtga gccagttggg ctggtccttt ttccaagtca aaaccaaaat actctatagg
     4081 gtttggaata gttggcttgt agaaaagtgg actgtctccg ttaaggagaa cagtagcagt
     4141 tggaactttc cgaatggcat ccaatatcat gttataggta gtatagattt caccgaaacg
     4201 gtccatctgg tcacggaaga tattagtaat gacaaaaaga ctaggctgga tatagtcaca
     4261 gatacgagat agactggctt cgtcgatttc taggacggca atatttttcc cagttttaga
     4321 agatttggct gttaagaagg ttgtcgcaat tcctgtaatc atgttggcac cgcttgggtt
     4381 ggtcagaact tgaccataaa cttcttttaa aataccgaca gtgagggcag ttgtcagggt
     4441 ttttccattt gttccagtga caacgacaat ctcgtagttc ttagctaggc tttgtaaaat
     4501 atctttatca aattgaaggg cgactttccc tgggagcgta cttccacgtc caagacggct
     4561 taaaacgaag tgggaagaac gcccagcaag aaggcccaaa gtagttttta agttcatgtt
     4621 tctattatat cacaaaagag ggaaaagaca gatttggtgt ttcgtagaag taaaaacagc
     4681 ccaaagaggg ctgtcagtta agatgagatt tcaacttaaa tcgcaaacaa gtcattcaag
     4741 ttctcagcca aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg
     4801 tt
//
LOCUS       DAVFJR010000074         4393 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVFJR010000074 DAVFJR010000000
VERSION     DAVFJR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.075"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..825
                     /gene="ply"
                     /locus_tag="VU722_002111"
     CDS             <1..825
                     /gene="ply"
                     /locus_tag="VU722_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU1772998.1"
                     /translation="IYYTVSVDAVKNPGDVFQDTVTVEDLRQRGISAERPLVYISSVA
                     YGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSG
                     ARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTA
                     YRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLK
                     GNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND"
     gene            835..1581
                     /locus_tag="VU722_002112"
     CDS             835..1581
                     /locus_tag="VU722_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEU1772999.1"
                     /translation="MFATKRVKGDLFSGLITDVDEEIMNSDQNRLDIDTIVIHHNGGL
                     SDEGARSTWYVSTGHGTSAHYQVTPDKIWGCVGEESVAYHAGNYEVNQRSIGIEHLNN
                     RGEPDWTIAEETYWNSARLIADICNRYNLPINGEAIHPHREFTATDCPGGIDLNRLIR
                     MAAEILAGDSFQVSKEEQPRDGDGERLVRVVEDDLYIRTGPGLAYPDQGFCPLGTFTI
                     MQVEEADGYTWGLLKSGRGWIALDYTEEIK"
     gene            1597..1821
                     /locus_tag="VU722_002113"
     CDS             1597..1821
                     /locus_tag="VU722_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398183.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1773000.1"
                     /translation="MKQKHKEDHKGEKVFRYSIRKYHFGAASVAVAALMFFANGTVQA
                     QTPEISPATESGTTRTSAFVSDSSGGCLES"
     gene            2019..>4393
                     /locus_tag="VU722_002114"
     CDS             2019..>4393
                     /locus_tag="VU722_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU1773001.1"
                     /translation="MLANLTLDSMKELHARVEAGLAGAKAVLENPHASQEEVNAQVRT
                     MRELTEEVNKALTGELTSPAELGEGRSVTLSEPSPTPRRGRGRRGPLTPPTAPVSTES
                     QEKKETVEEATDYTNGPGSYPLLENIHKLFQELKTSTGNPEQVQKLKEAYDKLNEALQ
                     TKEDGLVDQEVFNAALEEYKKAKHLKKGAEEDGKTRSRRSVSGLVYGFATGSTGKEIR
                     SKNDSGRERDTRNLYNGQNLNEIPLKYIATVETGTIRDISLSGFPTVGKDGKTWATIR
                     TRIDNGGKRAVLTITGQSPKDLYGIYNTILTVTEGNGHVSSKTQEVLYQLPKPEFDES
                     PLHPGKTAQQDVEGKAGDKPIVKGKIPTPPDGLKNSNIPKGTQIRMYLVRGGRNETFG
                     GIETSAEGYEIVAWGLVGGDGTSVIYPTQYKKQSIGDKPLRLIVAYVEPGTERISNRD
                     LVSPLSRDSITPTNPIDRDGAKSDADQKANAKKQSFDGIAHLTTEERNKANKQVDAAL
                     EKAKQAIDAANNQRDIETAKTTLEQDLGQISPTAEANKSAKSDADQKANLTLALIDDN
                     ENLSLFEKDAAKNQVRQALQDALKRIDQAKTQAEIDQAKQAALSSMDQVLAEALARAN
                     ARRLSGTRNRRTPPRRARRSVGFVGNSQTGTTPSAVDKSELRTLVEDLERRLKELEGL
                     SPEALEEAQRILREAQAALANDSLTAQELAELLAKVRQALNSIQVGTSADKSPSESNS
                     NKEAESAKEPTNATDVPLYGVFGAAVLSLLGALLFALAHKKNSQLDKLSRE"
BASE COUNT         1403 a          861 c         1097 g         1032 t
ORIGIN      
        1 atttattata cagtcagcgt agatgctgtt aaaaatccag gagatgtgtt tcaagatact
       61 gtaacggtag aggatttaag gcagagagga atttctgcag aacgtccttt ggtctatatt
      121 tcgagtgttg cttatgggcg ccaagtctat ctcaagttgg aaaccacgag taagagtgat
      181 gaagtagagg ctgcttttga agctttgata aaaggagtca aggtagctcc tcagacagag
      241 tggaagcaga ttttggacaa tacagaagtg aaggcggtta ttttaggggg agacccgagt
      301 tcgggtgccc gagttgtaac aggcaaggtg gatatggtag aggacttgat tcaagaaggc
      361 agtcgcttta cagcagatca tccaggcttg ccgatttcct atacaacttc atttttacgt
      421 gacaatgtag ttgcgacctt tcaaaacagt acagactatg ttgagactaa ggtgacagct
      481 tacagaaacg gagatttact gctggatcat agtggtgcct atgttgccca atattatatt
      541 acttgggatg aattatccta tgatcatcaa ggtaaggaag tcttgactcc taaggcttgg
      601 gacagaaatg ggcaggattt gacggctcac tttaccacta gtattccttt aaaagggaat
      661 gttcgtaatc tctctgtcaa aattagagag tgtaccggac ttgcctggga atggtggcgt
      721 acggtttatg aaaaaaccga tttgccacta gtgcgtaagc ggacgatttc tatttgggga
      781 acgactctct atcctcaggt agaggataag gtagaaaatg actaggaggg aagaatgttt
      841 gcgacaaaaa gagtaaaggg cgatttgttt tcaggactca tcacagatgt ggatgaggaa
      901 atcatgaata gcgatcagaa tcgccttgat attgatacta ttgtcatcca ccataatggt
      961 gggctgagtg atgaaggggc tagaagtact tggtatgtct ccacagggca tggcacatct
     1021 gctcactatc aggtgactcc tgataagata tgggggtgtg ttggcgaaga gagcgttgcc
     1081 tatcatgccg gcaactatga agtcaatcag cgttcgattg gtattgaaca tttaaataac
     1141 cgtggagaac cggactggac gattgcagag gaaacctact ggaactcagc acgtttgatt
     1201 gcagatattt gtaatcgtta taatttacca atcaatgggg aggccatcca tcctcacagg
     1261 gaatttactg ctacagattg tcctggtggg attgatctaa atcggctcat ccggatggca
     1321 gctgaaattc ttgctggaga tagtttccaa gtctcaaaag aggaacagcc tcgagatggg
     1381 gatggagagc gcctagtgcg tgtggtggag gatgacctct acatccgaac aggcccaggc
     1441 ctggcttatc ctgaccaagg tttttgccct cttgggactt ttaccatcat gcaggtagaa
     1501 gaagcagatg gctatacttg gggcttgctg aagtctggca ggggctggat cgcactagac
     1561 tatacagaag aaatcaaata gaaaaaggaa gaaagaatga aacaaaagca taaagaggat
     1621 cataaagggg aaaaggtttt tcgttattcg ataaggaagt accacttcgg tgctgctagt
     1681 gttgccgttg cggcgctgat gttttttgcc aacgggacag tacaggcaca aacgcctgag
     1741 atttccccag cgacagagag tggaacgact agaaccagtg cctttgtaag cgattcctcg
     1801 ggggggtgtc tagagagcta agtgaagaaa gtcctgtcac agcccctagt gaacccgagc
     1861 aatctagcca aggcaatcaa aagcctcaag aggcatcaga tgaaaaccag tctctagtaa
     1921 aaactaacga agaaggcaag aaggaaagcc aagcagagac aagtcatcct actgtagata
     1981 agtcacttgc cgagtctgca caaagtagcc tgcaagcctt gcttgccaat ctgacactgg
     2041 actctatgaa agaacttcac gctcgtgtag aagcaggtct agcaggagct aaagctgttc
     2101 ttgaaaatcc acatgctagt caagaggagg tcaatgccca ggttcgaacc atgagggaat
     2161 tgactgaaga agtcaacaag gctttgactg gtgagctcac atccccagct gagcttggag
     2221 aaggaaggag tgtgactctg agcgaaccaa gcccgactcc tagacggggg cgaggtcgca
     2281 gggggccgct aacccctcct acagcaccag tgtcaacaga aagtcaagaa aagaaggaaa
     2341 cagtggagga ggctacggac tacacaaatg gtccaggtag ctaccctcta ttagaaaaca
     2401 tccataaact cttccaagaa ctgaagacca gcactggaaa tccagaacaa gtccaaaaac
     2461 tgaaagaggc ttacgataaa ctcaatgaag cattacagac taaggaagat ggacttgttg
     2521 accaggaggt ttttaatgcc gcccttgagg agtataaaaa ggctaagcac ctaaaaaaag
     2581 gtgcggagga agatggaaaa actaggagtc gtagaagtgt ttctggactg gtctatgggt
     2641 ttgctacagg aagtaccggg aaggaaataa gatctaagaa tgattcagga agagaaagag
     2701 acactcgtaa tttatataac ggtcaaaact taaacgagat acctttaaaa tatattgcta
     2761 ctgtagaaac tggaactatt agagatattt ctttatcagg gttcccaaca gtgggtaagg
     2821 acggtaaaac ttgggctaca atcagaacga gaattgataa tggtggaaag agagctgttt
     2881 taactattac cggccagtct cctaaagatc tctatgggat atacaataca atcttaacag
     2941 taactgaagg aaacggtcac gtgtctagta agactcaaga ggttctgtat caactaccaa
     3001 aaccagaatt tgatgaatct ccactacatc caggaaagac tgctcaacaa gatgtagagg
     3061 gaaaagcagg agacaaacct atagttaagg ggaaaattcc tactccacca gatggattaa
     3121 agaattcgaa tattccgaaa ggcacccaaa taagaatgta tctggtccga ggtggacgta
     3181 atgaaacttt cggtggaatt gaaacttcag cagaaggtta tgagatcgtt gcctgggggt
     3241 tagtgggagg agatggaaca tcagtaatat atccgactca atacaagaaa caatccatag
     3301 gtgataaacc actacgtctt attgtagctt atgttgaacc agggacagaa cgaatatcaa
     3361 atagagattt agtttcacct ctttctaggg attccattac gccgaccaat ccgattgata
     3421 gggatggggc taaatcagac gcagatcaaa aagcgaatgc gaagaaacaa agctttgatg
     3481 gcattgcaca tctgacaacc gaagagcgca acaaagcgaa taaacaagtt gacgcagcac
     3541 ttgaaaaagc taaacaagca attgatgcgg caaataacca acgcgatatt gagactgcta
     3601 aaacaacgct tgagcaagat ttaggtcaaa tctctccgac agcagaggcg aacaagtcag
     3661 ctaaatcaga cgcagatcaa aaagcgaatc ttacccttgc tcttattgat gacaatgaaa
     3721 acctttctct atttgaaaaa gatgctgcta aaaatcaggt aaggcaggct cttcaagatg
     3781 ctcttaagag aattgatcaa gccaaaacac aagctgaaat cgatcaagcc aagcaagcag
     3841 ctttatctag catggatcag gttttagccg aggctctggc tagagctaat gcgcgaagac
     3901 tgtctggtac aagaaatcga agaactcctc cacgccgcgc tcgtagaagc gttggatttg
     3961 tagggaattc ccaaacaggt acaactccat cggctgtgga caagtctgaa cttcgtactt
     4021 tggtagagga tctggaacgc cgcttgaaag agttagaagg tctatctcct gaagcacttg
     4081 aggaagcaca gcgtatcttg agagaggcgc aagcagctct tgctaatgac tccttaacag
     4141 ctcaagaatt agcggaactc cttgccaaag ttagacaggc tcttaattct atacaagttg
     4201 gcacatcagc tgataagagt ccgtctgagt caaactcaaa taaggaagca gaaagcgcca
     4261 aggaacctac aaatgcgaca gatgtccctc tatatggtgt ctttggagct gcagtgctct
     4321 ctcttctagg agctctcctc tttgcactgg ctcataagaa aaactctcag ctagataagc
     4381 tttcaagaga att
//
LOCUS       DAVFJR010000075         4193 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVFJR010000075 DAVFJR010000000
VERSION     DAVFJR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.076"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..242
                     /locus_tag="VU722_002115"
     CDS             <1..242
                     /locus_tag="VU722_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEU1773002.1"
                     /translation="NSHLIYADYFEMKLKKLLKDDTKVFEKSTFKFVEGYKIYLTESK
                     ESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(600..1133)
                     /locus_tag="VU722_002116"
     CDS             complement(600..1133)
                     /locus_tag="VU722_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU1773003.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1222..1998)
                     /gene="recX"
                     /locus_tag="VU722_002117"
     CDS             complement(1222..1998)
                     /gene="recX"
                     /locus_tag="VU722_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU1773004.1"
                     /translation="MKITKLEKKKRLYLMELDEQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTHKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVNQETIQELILKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(2008..2784)
                     /locus_tag="VU722_002118"
     CDS             complement(2008..2784)
                     /locus_tag="VU722_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEU1773005.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2841..4193
                     /gene="rlmD"
                     /locus_tag="VU722_002119"
                     /pseudo
     CDS             2841..4193
                     /gene="rlmD"
                     /locus_tag="VU722_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
BASE COUNT         1355 a          710 c          757 g         1371 t
ORIGIN      
        1 aaaattcaca tctaatatat gcagactact ttgaaatgaa attaaaaaaa ttattaaagg
       61 atgacacaaa agtttttgaa aaatctacat tcaaatttgt agaaggatat aaaatatacc
      121 tgacagaatc taaagaatct ggaattaaac aaatggacaa tgtcataaaa tattttgagt
      181 ttattgaatc taaaagtatt gctttatatt ttcaaaaacg attaaatgag ctgatagatt
      241 aaatagcatt ttctctgttg agatattgtt tttaaaatac tgtactaaat gattgatgct
      301 atgtggaaat acaaaaaaat gtttttgata cgaagttgac ctgtattttt tatactaatc
      361 attttcgtat tttttgtatt aaacgatata agtttgttgt aaacttacaa ggaataaaga
      421 cattaaaaaa taacagtata tctatttgtt ttatatattt tacgaattct gcataaatct
      481 ctttctagta atgtgttgta actctgctat aatggattta ttcctttttg tgtttacaca
      541 atttatttta tactaccaaa aaaacaaggt caggattttg ttcctgacct ttgacaactt
      601 taccgattct ttagttctac atagcgcttg taccaaatgt ttacataggc ttctgagaaa
      661 ggaccacgtc cattgttaat ccaatcaaca agaattttga catgttcttt taaaatatag
      721 tccaagtcat cagaataatt cattttgcgt ttgtgacgct cgtactcttc aacgtccaag
      781 agacgttttt ctccatctgt aaaaatttta acatccaaat cgtaatcaat atacttcagt
      841 gcttcttcat ccagatagta ggggctagcc atattgcaat agtaagaagt tccattatca
      901 cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa agtaaacaat agccggttct
      961 cgagtgaccc aacgacgacc atcactttcg gtaacaagtg tatgatcgtt gacaccgata
     1021 atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc aagttcggtg aagactccca
     1081 tcatgcttat aactttgaat tgtaataaag tcgccttctt ttggaagctt cataactaac
     1141 caactttcta caatttataa gtttatcatt tactattgta ccataaaatt acctaaaatc
     1201 tgtgaatttc acttggaaat attaaagata ttctctaaga gcgcttgcta tatccgaaaa
     1261 atcgtagccc tttcgtgcta aaacttgagt taaacgctgc ttcagttcgt atccttcata
     1321 ctttcgagca tacttactat attgtttatc aagttccttt aagatgagtt cttgaatcgt
     1381 ttcttggtta acttggctat ctaagtcgtc aaaggcaatt ttagcatcag aataagagaa
     1441 gcccttgtta gtcaagttct ggataatctt atcttgcagg gcacgagatg gaagttttcc
     1501 ctcatatttt ttcaatagtt tattagctac acgttgagca acttcagaaa aatcaaattc
     1561 tttcaagttc tcttctatag tagattttga aatccctttt tgagctagtt tatgagtcag
     1621 cacataagga cccttgtctc ctgaaagttg attggtattg atgatagcat aagcgtactg
     1681 accatcatta atccacttat cttctttaag attagcaata acttgagaaa cgatgttttt
     1741 atcaatatcg tattttttca gatattctct gacttctttt tcagtgcgtg ctttaaagga
     1801 taagtggtag agagcgagat tcttaccata agaaaactgg gcaaaatcct gaatctcggt
     1861 cagttcctct ttactaatga ccttatctcg agacagcata aaacggacaa tggtatcttc
     1921 cgtgatataa gaggtttgct gttcatctag ttccatcaag tagagacgtt ttttcttttc
     1981 aagttttgtg attttcataa tttcctttca tctaaatgct tcgaaagctg caacaagtcg
     2041 tagtttatcc atatttacat attctctacc gtaatagtcg agaaataatt cagcatacgt
     2101 agcatcttgt aggttgtaat gaagggacca aattgcccaa aagaggtcga tatgtcggtc
     2161 actaaaacca gccaatccca agtcaataaa gcaagaaaaa tgagaggcat ccttcaagat
     2221 gaaatttggc aggcaggcat ctccatgaat aaaagcatca gctttgagaa tgtaaccttt
     2281 ctcttgtatc agttggtaag cttcttcacg actgtgaatg tgaaattgag gcagaagagt
     2341 cttgttataa aaagtcccct tctgatagtt ttttaaggct ttttctttat aacgcttcag
     2401 atgattttcc gacggaaaag attgtggttt aagactgtga agtttgttta atgcttgagc
     2461 cagggtttga cagagtcttt cgggttgatt taaaaaagcg agagcgttgc tgccaatggc
     2521 ttctttagtc agaaggaagt ccttatttgc tgataaatag gtaatcactg gagttcccaa
     2581 tccttcagtt tcgaaccaac ttgcaatctt agcttcttga gctaatctgc ctttttgatc
     2641 tatttttaaa tagtaacctg aatctatata taggacagtt gcacttgaat gagaagaact
     2701 atcagagaga ttagctccct tgatatagct tcgtaattgt tcagggaaat ctagtatact
     2761 aaagcgaggt gtttttgaat tcatgctttt attgtaacat attcttaaat atcttagaaa
     2821 ctccatggta taatagacat atgaatctga aagtgaaaca aaaaatacca ttaaaaatca
     2881 aacgcatggg aattaatggt gagggaatcg gcttttacca aaaacattag tctttgtacc
     2941 tggagctctc aaaggcgaag atatctattg tcagattact tctattagac gcaactttgt
     3001 tgaagcaaaa ttactgaagg tcaacaagaa gtctaaattt cgaattgtgc catcttgtac
     3061 tatttataat gaatgcggag gctgccaaat catgcacctg cattatgata agcagctgga
     3121 gttcaagacg gacttacttc atcaagcgct gaaaaaattt gctcctgcag gatatgaaaa
     3181 ttatgaaatt cgtccaacta ttggaatgca ggaaccaaaa tattacagag ctaagttaca
     3241 atttcagact cgaaaattta aaaatcaggt caaggcgggc ttatatgcac aaaactctca
     3301 ctatttagta gagttgaaag actgcctggt acaagataag gaaacccaag tgattgctaa
     3361 tcgcttagca gaattactta cttatcacca gattccaatc acggatgaga gaaaagttct
     3421 aggtgtccgt actattatgg tccgacgcgc gagaaagacc ggacaggttc agattattat
     3481 tgttacaaac cgccagctta atttaaccca actggtaaaa gagttggtta aagattttcc
     3541 agaagttgtg acagtagctg ttaatacaaa tacagctaaa accagtgaga tatatggtga
     3601 aaagacagag attatctggg ggcaagagag tattcaagaa ggtgtactca attatgaatt
     3661 ttcactatcc cctcgagctt tttatcaact aaatcctgag caaacagaag tcctctatag
     3721 cgaagcagta aaagcgctgg atgttgataa agaagaccat ttgattgacg cttattgtgg
     3781 agttggaacg attggatttg cctttgcaaa gaaagtaaaa acactcagag gtatggatat
     3841 tattccagaa gctattgaag atgccaagcg aaatgctaaa agaatgggat ttgacaatac
     3901 tcattatgaa gctggaacgg cagaagagat tattcctcgt tggtacaagg aaggctaccg
     3961 agcagatgct ttgattgttg acccaccacg tacaggtctg gatgataagt tattagatac
     4021 tattcttact tatgtaccag aaaaaatggt ttatatttct tgtaatgttt cgaccttggc
     4081 tcgtgatttg gtacgcttag tagaagtcta tgatcttcat tatatccagt cggtcgatat
     4141 gttcccacat acagctcgaa ctgaagctgt tgtaaaatta ataaaaaaag ttt
//
LOCUS       DAVFJR010000076         3416 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVFJR010000076 DAVFJR010000000
VERSION     DAVFJR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.077"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..94
                     /locus_tag="VU722_002120"
     rRNA            <1..94
                     /locus_tag="VU722_002120"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            146..218
                     /locus_tag="VU722_002121"
     tRNA            146..218
                     /locus_tag="VU722_002121"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:179..181,aa:Ala,seq:tgc)
     gene            343..3244
                     /locus_tag="VU722_002122"
     rRNA            343..3244
                     /locus_tag="VU722_002122"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            3321..>3416
                     /gene="rrf"
                     /locus_tag="VU722_002123"
     rRNA            3321..>3416
                     /gene="rrf"
                     /locus_tag="VU722_002123"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          978 a          678 c         1001 g          759 t
ORIGIN      
        1 cgtaaggagc cagccgccta aggtgggata gatgattggg gtgaagtcgt aacaaggtag
       61 ccgtatcgga aggtgcggct ggatcacctc ctttctaagg ataaggaact gcgcattggt
      121 cttgtttagt cttgagaggt cttgtggggc cttagctcag ctgggagagc gcctgctttg
      181 cacgcaggag gtcagcggtt cgatcccgct aggctccatt ggtgagagat caccaagtaa
      241 tgcacattga aaattgaata tctatatcaa atagtaacaa gaaaataaac cgaaaacgct
      301 gtagtattaa taagagttta tgactgaaag gtcagaaaat aaggttaagt taataagggc
      361 gcacggtgga tgccttggca ctaggagccg aagaaggacg tgacaaacga cgatatgcct
      421 tgggtagctg taagtaagcg atgatccagg gatttccgaa tgggggaacc caacaggtaa
      481 tacctgttac ccacatctgt taaggatgtg aggaggaaga cgcagtgaac tgaaacatct
      541 aagtagctgc aggaagagaa agcaaaagcg attgccttag tagcggcgag cgaaacggca
      601 ggagggcaaa ccgaagagtt tactcttcgg ggttgtagga ctgcaatgtg gactcaaaga
      661 ttatagaaga atgatttggg aagatcagcc aaagagagta atagcctcgt atttaaaata
      721 gtctttgtac ttagcagtat cctgagtacg gcgggacacg tgaaatcccg tcggaatctg
      781 ggaggaccat ctcccaaccc taaatactcc ctagtgaccg atagtgaacc agtaccgtga
      841 gggaaaggtg aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac
      901 aacaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
      961 acgttatgat gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtctgaatag
     1021 ggcgccttag tatcatgacg tagacccgaa accatgtgac ctacccatga gcaggttgaa
     1081 ggtgcggtaa gacgcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact
     1141 tgtgggtagc ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct
     1201 ttagggctag cgtcgacatt agagattctt ggaggtagag cactgtttgg gtgaggggtc
     1261 catcccggat taccaatctc agataaactc cgaatgccaa tgaattatgg tcggcagtca
     1321 gactgcgagt gctaagatcc gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc
     1381 ccaaaataat tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttagct
     1441 tagaagcagc tattcattca aagagtgcgt aatagctcac tagtcgagtg accctgcgcc
     1501 gaaaatgtac cggggctaaa acaatttacc gaagctgtgg atacctttat aggtatggta
     1561 ggagagcgtt ctatgtgtga tgaaggtata ccgtgaggag tactggaacg catagaagtg
     1621 agaatgccgg tatgagtagc gaaagacagg tgagaatcct gtccaccgta agactaaggt
     1681 ttccagggga aggctcgtcc gccctgggtt agtcgggacc taaggagaga ccgaaaggtg
     1741 tatccgatgg acaacaggtt gatattcctg tactagagta tgtagtgatg gagggacgca
     1801 gtaggctaac taaagcagac gattggaaga gtctgtctaa gcagtgaggt gtgaattgag
     1861 tcaaatgctt aattctataa cattgagctg tgatggggag cgaagtttag tagcgaagtt
     1921 agtgacgtca cactgccaag aaaagcttct agcgtttaaa catactctac ccgtaccgca
     1981 aaccgacaca ggtagtcgag gcgagtagcc tcaggtgagc gagagaactc tcgttaagga
     2041 actcggcaaa atgaccccgt aacttcggga gaaggggtgc tgactttaag tcagccgcag
     2101 tgaataggcc caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat
     2161 gtataggggg tgacgcctgc ccggtgctgg aaggttaaga ggagtgctta gcgtaagcga
     2221 aggtatgaat tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga
     2281 aattccttgt cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc
     2341 aacgagagac tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg
     2401 gaaagacccc atggagcttt actgcagttt gatattgagt gtctgtacca catgtacagg
     2461 ataggtagga gtctaagaga tcgggacacc agtttcgaag gagacgctgt tgggatacta
     2521 cccttgtgtt atggccactc taacccagat aggtgatccc tatcggagac agtgtctgac
     2581 gggcagtttg actggggcgg tcgcctccta aaaggtaacg gaggcgccca aaggttccct
     2641 cagaatggtt ggaaatcatt cgcagagtgt aaaggtataa gggagcttga ctgcgagagc
     2701 tacaactcga gcagggacga aagtcgggct tagtgatccg gtggttccgt atggaagggc
     2761 catcgctcaa cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca
     2821 catcgacggg gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg
     2881 tcccaagggt tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt
     2941 gagacagttc ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt
     3001 acgagaggac cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct
     3061 gggtagctat gtagggaagg gataaacgct gaaagcatct aagtgtgaaa cccacctcaa
     3121 gatgagattt cccatgatta tatatcagta agagccctga gggatgatca ggtagatagg
     3181 ttagaagtgg aagtgtggcg acacatgtag cggactaata ctaatagctc gaggacttat
     3241 ccaaagtaac tgagaatatg aaagcgaacg gttttcttga attgaataga tattcaattt
     3301 tgagtaggta ttactcagag ttaagtgacg atagcctagg agatacacct gtacccatgc
     3361 cgaacacaga agttaagccc tagaacgccg gaagtagttg ggggttgccc cctgtg
//
LOCUS       DAVFJR010000077         2971 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVFJR010000077 DAVFJR010000000
VERSION     DAVFJR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2971
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.078"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(56..328)
                     /locus_tag="VU722_002124"
     CDS             complement(56..328)
                     /locus_tag="VU722_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773006.1"
                     /translation="MFTTFFKKNQDNSDVFKKLIHRLSDMSVQDPEKIDRLLDIIFTP
                     DQGSEQLKTEATYREEILDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(366..749)
                     /locus_tag="VU722_002125"
     CDS             complement(366..749)
                     /locus_tag="VU722_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEU1773007.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(746..979)
                     /locus_tag="VU722_002126"
     CDS             complement(746..979)
                     /locus_tag="VU722_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773008.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGRERQFDESEFRKDEMSE"
     gene            complement(1030..2115)
                     /locus_tag="VU722_002127"
                     /pseudo
     CDS             complement(1030..2115)
                     /locus_tag="VU722_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            complement(2125..2766)
                     /locus_tag="VU722_002128"
     CDS             complement(2125..2766)
                     /locus_tag="VU722_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU1773009.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGELLVNQVQVWKSGLDDLDKATPKTLEESSSISSLPNTTTK"
BASE COUNT          864 a          569 c          449 g         1089 t
ORIGIN      
        1 atttgatacc accattataa catttagaaa aagcaaatgc accatttttg gtgcgttatt
       61 gactgttttt cctaaatctc tctaaattct tctccaattg ttccttatga agttgattct
      121 tagcttcttt taatgtgtcg tccaaaattt cttctctgta agttgcttct gtttttagtt
      181 gttctgatcc ttgatctgga gtgaaaatga tatctaacag tcggtctatt ttttcaggat
      241 cttggacaga catatcagat agtctatgaa ttagcttctt aaatacatca ctattgtctt
      301 ggtttttctt aaaaaatgtt gtaaacatct ataacctctc aaaaaaagca gcctatcagg
      361 actgcttagt gtaattccga aatcgcatca taaatggact gcaatttctt attgtcttta
      421 ttctttgtgt caatcaacgt atgtagctct tcaattttct tttgactact ttgaatatca
      481 ctattgttat ccgcaatcag tcttttaaga tgttgctgat aacttgtagt gatatctgtc
      541 tcttttcctg ttctaacctc tgtaactttg ggtttagaac tagaatttga ttccgtcaca
      601 ggtgcttgtt tgcgcttttg aaaagccgct tcataattta catcattacc tccttgatga
      661 tttccaaata aggccgcaat tttatctgga tcttcttgat tttctgattt actttctaat
      721 ggttgattaa aattccaatc ttttgtcatt cactcatttc atcctttcta aattcagatt
      781 catcgaattg tctttctcta ccgaaggcat ggtcaagagc ttcttcaaaa ctcatgtgac
      841 taatgctttg acgccttttg aacgtcgcaa acatcgctgt ctccagttgt tctttgtaag
      901 cagcgagttt ttctgtctct cttgctacct tactttcttg cctagtgacc ttttcttcta
      961 agcgttcaat aatggtcata tacgatcctc cttcattcta atattagcta aaacatcttg
     1021 attttgttat cacaattcta aacattgaga ggtttttctt actggttgat tcctcaatgt
     1081 ctcttttgca ttctcgatca tcaattgtaa atctgatttc ttttctctaa ggacatcatt
     1141 ccagtctact ttttctttcc cagatttatt atcagggaaa tccaggaaaa caggaaatcc
     1201 tgattgagat aacttatcag aaaaatcttt tcctgcatca tcacaatcta ccgcaagtgt
     1261 caataaatca ggatgattat caaaatagct ggtggtatca cgaattgtat tgattaaagg
     1321 caataacttt gaaggtatta ctgtatccaa aaattccaac ttctgatttt cttcagctat
     1381 cagtcgtaaa atttgataag caacaacaga cctttttaat ccttccatag ataccaaacg
     1441 aacatcagat agactttgtt gatgaagttc gtaatagctc attaagtcga tgaacgattc
     1501 acaaaagacc agtctattag gtttaccaat atcaaaggat attccaacat gtccatggct
     1561 tccttttaga atcgttttta acctctctct aggaagagag tgattcttat aaatccctta
     1621 gagacttgct gcctgcagct tgtaacgatg atcaaagctt ttaaaaacaa taacaggttc
     1681 aacagtttca tttgttttcc agctagcttg tgctatcaaa ccttgttgaa tcatcttttg
     1741 aacgatttct tctgaaattc ctctacattc tgttaaataa tatctagcca gactgcagtt
     1801 agaatcttct actctcttta aaggataata aaatggtctc tctctttttt cttgaacagc
     1861 ttctttttga aaaggttctt cagaaagaaa ggctagagct tctttaaagg aaattccctt
     1921 aacaagtcga acaaaatcaa tgacatcacc ttgaatatct cttgaaaacc atttaaaagt
     1981 attggtagtt gaaaaaatcc gaaatgaatc gtgttcagga tgttcataga cacggctaga
     2041 aacttgttta aaggagatac ctaaacgatt ggctacatca agaattgaaa tttgcttaca
     2101 ttcttctatt tccatgcaat atcatcattt tgtcgtagta tttggcagtg atgatattga
     2161 tgatgattct tctaaagttt taggagtggc cttatccaaa tcatctaacc cagatttcca
     2221 aacctgtact tgattgacca ataactcacc tggtagtttc gaataagaca acttaaccgt
     2281 tctggtttct gtctgattgg tctttgattg gttggcattc tttaaatcag atacataggt
     2341 tacattataa gagaccatgg caatggcttg attcgtagtc tgattgacaa agatatcagc
     2401 tttttcaaaa tgataatcta aaatataatc cttatacact tggttcatgg catcattttg
     2461 acttgacaat tcttgagaat aagccgattc agtcatataa ggttgaatac gtgtattatt
     2521 ttctccgagc ttttctttcg tatagtactg cgtcaaaaat tcttttacag tatccgatga
     2581 caaaatgctg gctttatctt ctgcttgttt atcctctaca agtttagctg cagccaattc
     2641 aatctcttta cgactttgtt tagcagtcga gtgttgacca gcagtatatc ccatcatgag
     2701 aataaagcta gttgcagcca ctgctccaac actaattaag gctttagttt tgactttatt
     2761 taacatctta gaccttcttt ctataaaaac taggtcaaga atagcagata aatcttgaaa
     2821 aaagtatcac agaagtaaaa atgccacccg aaggtggcca atataactta caaaattagt
     2881 aatccgtctg ataaagtttt ttatacaaac catttttcat attcaatagt tctgtatgac
     2941 ttccttgttc tacaatttct cctcgtaata t
//
LOCUS       DAVFJR010000078         2759 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVFJR010000078 DAVFJR010000000
VERSION     DAVFJR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.079"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            21..1025
                     /locus_tag="VU722_002129"
     CDS             21..1025
                     /locus_tag="VU722_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1773010.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKNEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKVYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLVSVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            1094..1960
                     /locus_tag="VU722_002130"
     CDS             1094..1960
                     /locus_tag="VU722_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1773011.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGIKQIQDVLPFDSDLNRLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            1957..2715
                     /locus_tag="VU722_002131"
     CDS             1957..2715
                     /locus_tag="VU722_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1773012.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSSEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGQIIQDLNQEEKAKMKISDYYQLFE"
BASE COUNT          857 a          482 c          611 g          809 t
ORIGIN      
        1 atattacgag gagaaacaga atgaaaaata aacgtttaat tggaattatc gctgcattag
       61 cagtcttagt agcaggaagc ttgatttatt cttcaatgaa taaatcagaa gctcagaata
      121 ataagaatga gaagaaaata accaagattg gtgtgcttca atttgtgagc catccatccc
      181 ttgatttgat ttataaaggg atccaagatg gacttgcaga agaaggatat aaagatgatc
      241 aagttaaaat tgattttatg aactcagaag gtgatcaaag taaggttgcg acaatgagta
      301 aacaattggt tgcaaatggg aatgaccttg tggttggtat cgcaacacca gcagcccaag
      361 ggttggctag tgcaacaaaa gacctaccgg ttatcatggc cgctattaca gacccaattg
      421 gtgctaactt ggttaaagat ttgaaaaaac caggtggcaa cgttacaggg gtatctgacc
      481 acaatccagc tcaacaacaa gttgaactca tcaaggctct gacaccgaat gtgaaaacaa
      541 tcggagctct ttactcaagt agcgaagaca attcaaaaac acaggtcgaa gaatttaagg
      601 tttatgctga aaaagcaggt ctgacagtgg aaacatttgc agttccttca acaaatgaaa
      661 ttgcctcaac tgtcactgtt atgactagca aggtagatgc tatttgggtt ccaattgata
      721 acaccattgc atcaggattt ccaacggttg tctctagcaa tcaaagttct aagaaaccaa
      781 tttatcccag tgcgacagct atggtagaag taggtggttt ggtatcagtt gtaattgacc
      841 aacatgacct tggtgtagca acaggtaaaa tgattgtgca agtcttgaaa ggtgcaaaac
      901 cagccgatac cccagtcaat gtcttttcaa ctggtaagtc agtcatcaat aaaaaaatag
      961 cacaagaact aggtattact attcctgagt ctgttctcaa agaagcagga caagtcatcg
     1021 aataaataag gtagggagga ggagactctt tccatttttt aaaaagatga atatagaaag
     1081 gattaaataa aatatgattg tttccattat ttctcaagga tttgtctggg ctattctagg
     1141 tctgggaatc tttatgacat ttaggatttt aaactttcca gatatgacga cagaaggttc
     1201 cttccctctt gggggagctg ttgctgtcac tttgataacc aaaggcgtga acccattttt
     1261 agcgacactt gttgctgtag gagcaggttg tttggctgga atggcagcag gccttcttta
     1321 tacaaaaggg aagatcccaa ccttgctctc agggattttg gtgatgactt cttgtcactc
     1381 aatcatgctc ttgattatgg gacgtgcgaa tttaggcctg cttggaatca agcaaattca
     1441 ggatgttttg ccttttgatt cggatttgaa tcgactcttg acaggtctca tctttgtgag
     1501 tattgttatt gctctcatgc tctttttctt ggacactaaa ctcggacaag cctatattgc
     1561 tacaggggat aatcctgata tggctagaag tttcgggatt catactggac gcatggagct
     1621 catgggcttg gtcttatcaa atggtgtgat tgcccttgca ggtgccctca ttgctcagca
     1681 agaaggctat gccgatgtgt ctcgagggat cggggttatc gttgtggggc ttgcaagttt
     1741 gattattgga gaagttattt tcaagagttt gagcttggca gagcgtttgg ttactatcgt
     1801 tgtaggttct atcgcttatc aatttttagt gtgggcagtt atcgcacttg gctttaatac
     1861 aagttacctt cgtttataca gtgccttgat tttagcagtc tgcctcatga ttccaacatt
     1921 taagcaaaca atcttgaaag gagccaagtt aagcaaatga cagcaattgt agaattaaaa
     1981 aatgcaacca aaatcgttaa aaatggcttt gatgaagaaa agattatttt aaatgatgtt
     2041 tccttagaaa tttttgaacg ggactttatc acgattttgg gcggaaatgg tgctggaaaa
     2101 tcaaccctct ttaacactat agcagggacc ttatcactaa ctagtggaac tatccgtatt
     2161 ttaggtgaag atctcactaa gttttcatcc gagaagcgtg ccaagtacct gtctcgtgtc
     2221 ttccaagatc caaagatggg aacagctccc cgtatgacgg tcgctgaaaa tcttttaatc
     2281 gccaagtttc gtggtgaaaa gcgtggattg ttaccacgac gcttgactag ctataaggat
     2341 gaatttcagg caaccattga aaaagtagga aatggtcttg agaaacactt gaatacaccg
     2401 attgagttct tatcaggtgg acaaagacag gctttgagtc tcttgatggc aaccttgaag
     2461 cgacctgaat tactcttgtt agacgagcat actgcagctc ttgatccaaa gacaagtgtt
     2521 gccctcatgg aattgacaga tgaatttgtc aagaaggatc aattgacagc gcttatgatt
     2581 actcatcata tggaagatgc tcttaagtat ggcaatcgct taattgtcat gaaagaagga
     2641 caaattattc aagatttgaa ccaagaagaa aaagcaaaaa tgaaaatctc tgattattat
     2701 caactatttg aataaagtag ggaaaatgag tgaaatggtt tacttttttt ctgaaataa
//
LOCUS       DAVFJR010000079         2745 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVFJR010000079 DAVFJR010000000
VERSION     DAVFJR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.080"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            706..2628
                     /gene="ltrA"
                     /locus_tag="VU722_002132"
     CDS             706..2628
                     /gene="ltrA"
                     /locus_tag="VU722_002132"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU1773013.1"
                     /translation="MTKPKNDDKLLKHQKLRYAEYYGMTEIFDDLYSKSQNGFSFKNL
                     MNIITSPENILLAYRTIKRNGGSQTEGVDGVTIKDLENLTQEDFISKVQRRFQYYRPR
                     KVRRVEIPKPNGKKRPLGIPSMWDRVAQQCILQVLEPICEAKFYKHSYGFRPLRSADN
                     AIMDCMYRMNKSHMTYVVDVDIKGFFNEVNHTKLMRQIWTLGIRDKQLLVIIRKMLKA
                     PIVLPNGKVTYPTKGTPQGGILSPLLANINLNEFDWWIGRQWEERDCKELVPQYNSKG
                     TRHKSHVYRKLRTSTTLKEVYIVRYADDFKIFCRNRNEAERTFKAVKLWLKERLNLPI
                     SEEKSQITNLRKKSSEFLGITLKLVSKNNRLVCFSHIASKAKKRIKHQLKQQMKLIQI
                     KGAKETIIREIQKYNSMVIGIHNYYSMATHVSKDLEEIHYQLYLSFKNRLQAKGLTKI
                     GEYKGKDKGLLPYLQSQNIRYLMGYPILPISYVKTRTLKGRNKNLNRYTPEGRKLIHK
                     QQESVETWKLKWLREHSIINKRATVEYNDNRISLFVAQKGKCAVTGQELDMDDIHCHH
                     KRPWLETKDDSYRNLIIVGRDIHRLIHATNEKVIKNLFQLLNLSDTGLTKLNQLRELA
                     GNSPLLKENLNLEQLC"
BASE COUNT         1004 a          425 c          577 g          739 t
ORIGIN      
        1 aaaaggttag acacgttctt gaaaaatcaa cctgataatc aggttaaatt tgaatagaat
       61 ggagaactct tatcttgaaa attggaatga aggggtaacg ccctgaaacg atttctctaa
      121 tactccgaca tgcgtttatc ttgtgcaaag gtaaaggttt gaagctcggt gaagtcggct
      181 gaaagatacc gtcattctta aggacttaag aatcgaaagt gttccagagg tggaatatgt
      241 atctgatagg tcgggagtca ttaaaaacta aatagggtga gaatgtgcat gagcactgac
      301 gaaccagcga atgtacgctc cgaaggcgag tacgtagaaa tgcgtataac aacgtaagtt
      361 gtttcaactt gaggaagagt aagaatcgac gatatgaaat tccttgttat gttacaggca
      421 tatcaaagtt gaaggggtat agctaggcac ctaagtttag tattgataaa gataagggaa
      481 cgtcgaaagc tagagatgtg gaggttgcac aaccagagaa acattggaaa gaaaatcata
      541 actttcctta atctctagtg agagtggtgg cacgaccttt gaaagtgttg taatgatact
      601 ggaggaacag ccactagtca atagtgtatt gttatgaact ttatcatttc atggattctt
      661 gtaagacata aaaggtcacg aatccaaaga gaggagtgat agaccatgac gaaaccaaaa
      721 aatgatgaca aactattaaa acatcaaaaa ctaaggtatg cggaatacta tggcatgacc
      781 gagatatttg atgatttata ttccaaaagt caaaatggat tcagttttaa gaacttaatg
      841 aacattatca catctcccga gaatatactg ctcgcttatc gtaccataaa gcgaaatggt
      901 ggtagtcaaa ccgaaggagt agatggtgtt accattaaag atttagaaaa tctgacccaa
      961 gaagacttta tctctaaagt tcaaagaaga tttcaatatt atagacccag aaaagtcaga
     1021 agagtagaga ttcctaagcc aaatgggaag aaacgaccac ttggcattcc ctcgatgtgg
     1081 gacagagtag ctcaacagtg tattttacaa gtgttggagc caatctgtga agcgaaattt
     1141 tacaaacaca gttatggatt tagaccctta aggtcggctg ataacgctat tatggactgt
     1201 atgtatcgta tgaataaaag tcatatgact tatgtcgttg acgttgatat taaaggcttt
     1261 tttaatgaag tgaatcatac taagttaatg cgtcaaatct ggacattagg tatcagggac
     1321 aaacaacttc tagtgattat tcgaaaaatg ttaaaagcac caattgttct tccgaatgga
     1381 aaagtgacat atccaactaa gggcacacca caaggaggta tcttatctcc actacttgcc
     1441 aatatcaatc tcaatgaatt tgattggtgg ataggacgac aatgggaaga aagagattgt
     1501 aaggaattag ttcctcaata taattccaag ggaacaagac acaagtcaca tgtttacaga
     1561 aagctgcgaa cttcaacgac gctaaaagaa gtttatattg tccgatatgc ggatgatttt
     1621 aaaatctttt gtcgaaatag gaatgaggca gagcgaacgt ttaaggctgt aaaattgtgg
     1681 ttaaaagaac gacttaacct ccctatttca gaggaaaaat ctcaaattac caatctgaga
     1741 aagaaaagca gtgaattcct tgggattact ttaaagctag tttctaagaa taatcgtttg
     1801 gtttgtttct ctcatattgc atcaaaagcc aagaaacgta ttaaacatca actgaaacaa
     1861 cagatgaaat tgatacaaat taaaggtgct aaagaaacaa ttattcgtga aatacagaag
     1921 tataatagta tggttatcgg tattcataac tattatagta tggcaacaca tgtgagtaag
     1981 gatttagaag aaattcatta tcagctttat ctctctttta aaaatagatt gcaggcgaaa
     2041 ggtctgacaa aaataggaga atacaaggga aaagataaag gacttctccc ctacctccaa
     2101 tctcaaaata ttcggtactt aatgggttat ccaattcttc caattagcta tgtcaagacg
     2161 agaacactaa aaggaagaaa taagaatctg aataggtata ctcccgaggg gagaaaattg
     2221 attcataaac aacaggaatc tgttgaaaca tggaaattaa aatggctgag agaacactca
     2281 attataaata agcgtgcaac agttgaatac aatgataatc gaatttcttt atttgtagct
     2341 caaaaaggga aatgtgctgt aaccggtcag gaattggata tggatgatat tcattgtcac
     2401 cataagagac cgtggttaga aacaaaggat gactcttata ggaaccttat cattgttgga
     2461 cgagatattc atcgcctgat tcacgcaaca aatgagaagg ttatcaaaaa tctctttcag
     2521 cttttgaatt tgagtgatac aggactgacc aaattaaatc agttgcgcga acttgcagga
     2581 aattcaccat tattgaaaga aaatttgaac ttagaacaat tatgttaatc atattaatac
     2641 agcacgataa agcaaaatcg tgataataca ctattgatgg aacgccgtgt gcggtgaaag
     2701 tcgcacgcac ggtgtgaagc gggggaaaag atggagatag tatca
//
LOCUS       DAVFJR010000080         2636 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVFJR010000080 DAVFJR010000000
VERSION     DAVFJR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.081"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..443)
                     /locus_tag="VU722_002133"
     CDS             complement(<1..443)
                     /locus_tag="VU722_002133"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU1773014.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAEKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATV"
     regulatory      complement(843..938)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(1322..1450)
                     /locus_tag="VU722_002134"
     CDS             complement(1322..1450)
                     /locus_tag="VU722_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU1773015.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(1561..1704)
                     /locus_tag="VU722_002135"
     CDS             complement(1561..1704)
                     /locus_tag="VU722_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU1773016.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(1716..2543)
                     /gene="xth"
                     /locus_tag="VU722_002136"
     CDS             complement(1716..2543)
                     /gene="xth"
                     /locus_tag="VU722_002136"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU1773017.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
BASE COUNT          790 a          502 c          545 g          799 t
ORIGIN      
        1 tggactgtgg caccggcctg ttcgatgatt tgaatcaagc ctttagcagc ttggccatta
       61 gcaaggaaat cgtcgataat caaaaccttg tcctctggtg agaggaattt ttcagcgata
      121 gaaacggtgc tggtcacctg tttggtaaag gagtagactt gagcagttaa gatgccttcg
      181 ttcatggtga tgttcttagc ttttttggcg aaaatcatgg gaacgtttaa ggcttcagct
      241 gtaaaaacgg ctggggcaat acccgacgct tcaatggtta cgaccttggt aatgccagta
      301 gcagcaaatt tttccgcaaa aaccttacca atctctcgca tcaagctaaa gtcaacttgg
      361 tgggttaaaa aggaatctac cttgaggatg ttatcaccca agatatgccc atccttgagg
      421 atgcgctctt ctaataattt cataagacct cctaaagtct aaaagttaat ttacttgttg
      481 tttaaatatt tctatagtga tcccttttgc taatactata tatttgataa aactattacg
      541 agcgaagcga gtcttatcaa atatttcctg atgtagtggt atcatagaca ataatcttgt
      601 tattgtctat gacgggattt ttgagagtaa aatagttcgg ggaactattt tagcctaagc
      661 ctagaaatga aagagctagg ggctcaaaaa ttagggatga aattccctgg attcctgaaa
      721 ttattcacag gataatttca cctcccgtcc gcactaatta agggaaatat taaaaatatt
      781 caaaaaagac ctacttaatc tctaagtaag tcccccaaat aggcatggca aaaacggcca
      841 tatctcactg ctgacttact tattgttagg tgttccggca ccttgtagaa acgtcgtgcc
      901 aattcacgac ataaacaagt aaaacgatat tcaattttaa ataggcttga gccaatgttt
      961 ttattttaca ctaaataact ttagaaatca actattttgt tagtgttttg gtttaaaaaa
     1021 cgaacaaaca gaagagaggg cgaacaaaaa actccgttgt aagctaacat ttatactaaa
     1081 tgaaaatcaa agagcaaact aggaagctat ccacaacctc aaatcactgt tttgaggttg
     1141 tggatagaat tgacagagtc agtatcatat acctacggta aggcaacgtt gatgtggctt
     1201 gaagagattt tcgaagagta ttagaagatt tttccatcat aaaaggcata ctatcaagtt
     1261 tttaaacacc tgacaatatg cctttttcta actttaaaga cttttcccaa tttttattat
     1321 tctactcgct aaatcttaaa aaatagccat ttggatccaa aactgcaaat tcatgaggat
     1381 agatatagtg atcactgaca cgaaactttc tcttggtcaa gggacgataa ataggatagt
     1441 ttgccttcat cactctttaa tagagttttg aaacatcctt tatgccaaag gagagattga
     1501 ctccacgacc aaatggatag gtcagttcag ctagttgatc ctttgttccc tcctctaaca
     1561 ttagttgaca ctcttcaaga gaaagagaaa gttttcttct ggacgttggt attcaatcct
     1621 aaaacccagt aaaccacagt agaaggaccg ggactgttcg atattcgata caagcaactc
     1681 gggaatgacc gcattgtagt ccatatagaa aatccttaca agtcaatttc caagacaatc
     1741 ggtgtatggt cttggcgagc acctgagtca atcatatcag atttagtgac cttgtcagcg
     1801 atacggttac ttgtgagcca gtagtcgatt ctccagcctg tattgttgat tttagaagtt
     1861 ttgctgcgtt gtgcccacca agtgtagcgt tcaggaacat cgccatgaac atggcggaag
     1921 gtgtctgtaa atccagttgc caaaaggttg gtaaatccag cacgttcctc gtcagtaaat
     1981 ccaggtgaac ggcggttgct agcaggattt gcaaggtcga tttcattgtg ggctacgttg
     2041 tagtcaccgg tcgcaaggac tggtttttct ttgtctagtt cagccaaata ctcagcatat
     2101 ttggcatccc agacttggcg ttcttccaag cgtttgagac cgtcaccagc gtttggagtg
     2161 taaacttggg ttacgaaaaa tgcatcaaat tctagagtga tgatacgacc ttccaagtcc
     2221 atggtagaag gggcaccgat ttctgggaag ctgatagtag gtgtaagttc tttcttataa
     2281 aggaacatgg ttccagcata gcctttacgg gcaggctctt gggaagaacg ccacgtgttt
     2341 tcgtagcctg ggaagagttc ttctaaaatt tccacgtgtt tctttgtagg tcctttggca
     2401 gaaagcttgg tttcttggat agcaatgata tcagcatttt cagcgaccaa ggtttgtagg
     2461 acttcttggg acaatttggc acgagctgag tcactagtta gggcagcgtt tagggaatca
     2521 atattccatg agataagttt cataaagtta cctttttcat tcagattata gattttatta
     2581 taccaaaaaa agatctattt ccccaacgta tagtttgaaa aattactctc tttcgt
//
LOCUS       DAVFJR010000081         2101 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVFJR010000081 DAVFJR010000000
VERSION     DAVFJR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.082"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(28..813)
                     /locus_tag="VU722_002137"
     CDS             complement(28..813)
                     /locus_tag="VU722_002137"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU1773018.1"
                     /translation="MKHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVNEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRGSSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            complement(1163..1591)
                     /locus_tag="VU722_002138"
                     /pseudo
     CDS             complement(1163..1591)
                     /locus_tag="VU722_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901186.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            1866..>2101
                     /locus_tag="VU722_002139"
     CDS             1866..>2101
                     /locus_tag="VU722_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1773019.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDITNKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPARILLRKRR"
BASE COUNT          630 a          480 c          341 g          650 t
ORIGIN      
        1 aaattcaaag aatgatgcaa gtatttttta ttttcctgta aatttaggtc ttcttctctc
       61 cgaatgagct cgcactcctt ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt
      121 cagttctaaa gtagcgtaac cctgccagtc tttaaattgg ctctcccaaa ccaacttctt
      181 aatggcagca taggaattac ttgaaccacg tcttaatttt ttaagaagct gttctctcgt
      241 cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac ccccattcta gggctttttc
      301 tgccgttaaa gcctctcctg tcatagctaa ttgagcagca cgcgtcacac cgatactgcg
      361 gcttaagaga tgaattcccc ctgcatctgg agccaaacca acaccaacaa aggcttggat
      421 aaacttagcc ttatccgtcg ccaaacagaa atctgccgca acagccatat tcgctgcggc
      481 acctgcaaca gcaccgtcaa cttccattaa aacaggtttg gctatttgct tgattttata
      541 agaaatcgta ttgaccaact ctgcgatttt tgtcagtgat ggaatatcat cctcattcac
      601 tgcccgcttc atctctacca aatctccccc aactgagaag acctttccat tggcattgat
      661 taagataaaa tgcacagctg gattttcttc tgccaaagtc agagcttcta aaatctcctc
      721 acacatggga atatgaaaac catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa
      781 gtcctcttca agctgataaa taatgtgttt catcagagct cctttttatt ttataagcag
      841 tttatactct tcgaaaattt cttcaaaccg cgtcagcttc catctgcaac ctcaaaacag
      901 tattttgagc tgacttcgtc agtttcatct acaacctcaa agcagtgctt tgagcagtct
      961 gcggctagct tcctagtttg ctctttgatt ttcattgagt gttaaattat ttcactttca
     1021 aagtatatct tttttaggag cagaaagcaa gaaaaaatcg actgaaagtg tctcagccga
     1081 taagaaaggc tcgctttagg ctagaaagca tcttattgct ctggcacata atgagcaacc
     1141 tggcttgttt ttgcaaaagc cattatttca aatcctccaa aaattgataa agattggtca
     1201 aacctttgct catgacatcc atttcttcct tactcacacc atcaatgatt ttttcaacca
     1261 tggccttgtg gaagcgttta tgtagcctat gaaccaagcg acccttcttt gtcaaatgta
     1321 gatgcaccac acgacgatcc tgctctgagc gaatgcgttc aatgtaagcc ttgcgttcga
     1381 gattattcaa actagtcgta actgtcccaa gaatcaccag caactctttt gacacttgac
     1441 ttggtgtcac gtctgggaat ttcccaatca catcaatcgt atgcatttct ttgatggaga
     1501 tatccttgaa acgactacct ctcaagttca cttcctcaat gacaaggaca ttgttaaata
     1561 ttcattaatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa aacttttaca
     1621 atcaaaacat ttgacaagag aattatatca aagctcaaac aatgatgcaa gtatttttta
     1681 ttttcctgta aatttaggcc ttcttcgttt gaaaacgctt atatatactc ctaaggaaag
     1741 agactctata atatttgtag tgggtaaatc cactatagat attatggagc ctatttttgt
     1801 gtagaaaaaa agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga
     1861 tttatatgga acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc
     1921 agattttaga catcaccaat aaggatacac acaaggaaat catcgccaaa ctggactacg
     1981 acgccccatc ttgccctgag tgtggaaacc aattgaagaa atatgacttt caaaaacctt
     2041 ctaaaattcc ttatcttgaa acgactggta tgcctgctag aattctcctt agaaagcgtc
     2101 g
//
LOCUS       DAVFJR010000082         2085 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVFJR010000082 DAVFJR010000000
VERSION     DAVFJR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.083"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(179..982)
                     /locus_tag="VU722_002140"
     CDS             complement(179..982)
                     /locus_tag="VU722_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU1773020.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1261..2016)
                     /locus_tag="VU722_002141"
     CDS             complement(1261..2016)
                     /locus_tag="VU722_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU1773021.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
BASE COUNT          679 a          415 c          317 g          674 t
ORIGIN      
        1 cgaattaagg taaaactaaa aggacttagc cctgtgcaat acagaactaa atccttcgga
       61 taaattaatt gtctaactgt ttggggtcag tacattttaa cacttgatac tatgcgtttt
      121 attgtgggaa tgtttacttc attttttcct aaaattcaat gtttactcag tatttggatt
      181 atgaaaaatc gaggtctaaa tctagataca ttttttctga agacaaatca ttttgaccac
      241 cgagcaagag attttcaaaa aaagctgtta aaaactcagg acgtcgctgt aaaatctttg
      301 cattatctaa taccaaggca tcacgaaaat acttggaatg ttgctgaaat ggtatattat
      361 caatatcaaa accaaactca cgaagatact gaatcaaaaa gaccgttact gtccgagtgt
      421 ttccttcgcg aaatggatga atctgccaga ttcctgaaat aaaatgctgg atttgtttaa
      481 ccacatccgc ctgagttagt gtcgcatatg caacttgttt ttcctgatta aaatcataat
      541 ctaaggtcat ttgaatcatg gagtaatcag agtacacaac actttcacca ttcaaaacag
      601 gttcattctt tgtgatattg gtctgacgaa attgccccac cggaatagag ggttcaaata
      661 tatcttgaaa caactcctta tgaatagcaa gtaaggtcgc aggactaaag ctaaagcctc
      721 ttcgagacaa tagttctaca atacgtagag aaaccaagtc tgcctcttcc gtacttgcat
      781 caatagtatg gtgataagcc gttgcatcct cataaacctg ctcataagtc agttctcccc
      841 gggactgttt ctcagccaaa gattccatat acgctgatgg cactagattg tcaactttct
      901 gcagaccaaa acctatccgc cataaatcac gcttcgcttc ataagacaag tttggattgt
      961 caatgttgta agttggttgc atagaaatat cctttcaatt gtttttcttc attaccagta
     1021 aatcacgaaa ttggttggaa actggcttaa actataaaaa gtcctcacaa taggttctat
     1081 gatatatata tatatacttc atgtaaataa taaaagagtt ataatcagca ctactgataa
     1141 attcaatacc gatttcgcca tcttaaaact tagtcaaacg aataccgttg atttccagtt
     1201 cattaagtcg ttgacctgtc aagacttctc gttccttcaa ctggaaaagt taagggggaa
     1261 ctaatacaaa tcctctacgc ttctatattc aatgatttca tttttgataa tattcttttt
     1321 aaactcaaaa tgttttaaag gattatcgat taacactaac tttggaatat catctagatt
     1381 tgtgaccaag gataaaataa aatccgattg aaactccttg actttttcaa attcttttgc
     1441 agttaaacgc acacgcccct tagattttcg gatacctttt acttcggcaa ggtaagaata
     1501 ctcttggaca tctacctgaa agtcatatcc atcaccataa agacgggcat cggttaactg
     1561 tccaccttgg aatttttctt ctttatcaaa atgaaggata aaataattct cagcctccat
     1621 tcccgtttcc tgtagacgtt tgaatttagt tcgaactatt ggtttttcaa cgatggttat
     1681 gcctgttttc ttcccttcac tggcaagtaa cattttaact atttcagcat aactatgaac
     1741 atcttcattt ccaaacatca tatcaattaa atctttacga aaacgataaa cttcagcttt
     1801 ctgccaccaa ccttttcgat tattgtcaaa ataaggatca aataaatcca ttctattttt
     1861 tacaactcca gttgtttcag caattcccag agaaaccaca tagcgataaa actccgactt
     1921 gctagagcat tgaaattctt ttataaaaag cttgtcaaac ttggcaagac cgtagccaat
     1981 taaatttaac aattcataat gagggtgttt ggacatcact ttctccatca atagatattg
     2041 atttcattat accaaaaaac acggcattac accatgtttc tatgt
//
LOCUS       DAVFJR010000083         2055 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVFJR010000083 DAVFJR010000000
VERSION     DAVFJR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.084"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..452
                     /locus_tag="VU722_002142"
     CDS             <1..452
                     /locus_tag="VU722_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU1773022.1"
                     /translation="EEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLIAVF
                     CAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKEHWISYQKTAQLLEKEKFLYQCQT
                     EKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASAEAPGKKE"
     gene            465..1073
                     /locus_tag="VU722_002143"
     CDS             465..1073
                     /locus_tag="VU722_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773023.1"
                     /translation="MFQSSYLLPLLWLKKEADKEKMSATQCQIFFFYYQLFELLFARE
                     SDLKDLCLGGQGFYFSQLEKDLLSGVSRFLTNLEGKGTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQAVERLETPLLLSFQDRQDLMWIYQSALEKDYSVKVIGDKHFVL
                     KRQDATKLTGRQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1144..1476
                     /locus_tag="VU722_002144"
     CDS             1144..1476
                     /locus_tag="VU722_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773024.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEVLDHLVQPQLISLNKSEF
                     MQLNSGTY"
     gene            1487..>2055
                     /gene="ply"
                     /locus_tag="VU722_002145"
     CDS             1487..>2055
                     /gene="ply"
                     /locus_tag="VU722_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU1773025.1"
                     /translation="MANKAVNDFILAMDYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQ"
BASE COUNT          632 a          382 c          467 g          574 t
ORIGIN      
        1 cagaagaaat gtacctgaca gagcgattag acgtacagat agctcatttt ttaaagaaaa
       61 gcgttcaaca tcgtagacgc tataaggtat taaaaataac agaaatcgtg gcaggtttcc
      121 tcatagctgt cttttgtgct attcctatgc caggtgatcg ctaccgtttg atttcggttg
      181 ccttatccag tctcggcttg ctgtgtgagg ggattatcaa tttgtataat gccaaggaac
      241 actggatttc ttaccaaaag actgcgcaac tcctggagaa agaaaaattc ctctatcaat
      301 gccaaacgga gaaatatgca ggaaagacca aggcttttgc cctatttgtc aagacatgcg
      361 aaggtcttat ctcagaggaa atcaaccagt gggaaagtat ccagtcaaaa gaagtggcag
      421 ctagtgcaga agctccaggg aaaaaagagt aggaggtgga ggaaatgttt caatccagct
      481 acctattgcc cttgctctgg ttaaaaaaag aagccgataa ggaaaagatg agcgcgaccc
      541 agtgccagat atttttcttt tattatcaac tgtttgaact cttatttgct agagaaagcg
      601 acttgaaaga cttgtgtctg ggagggcaag gtttttattt ctcgcagtta gagaaagatt
      661 tgctttctgg agtttcccga tttctaacaa acttggaggg aaaagggact ctcaaggcta
      721 accaagaagt atcagctcgc aaagcccttt ttctagcctt gacaactagc cagtcagatt
      781 ggcaggaatt agctcctgtt tttgattttt atcaggctgt agagagactt gaaacgccct
      841 tactcttgag ttttcaagac agacaagatc tgatgtggat ttaccaatca gctttggaga
      901 aagattatag tgtcaaggtg attggcgaca agcattttgt attgaagaga caagatgcta
      961 ctaaattgac agggcgccaa actcaaactt tggaaattct gagtcaatca gaagacttgg
     1021 tcaatcctgt ctatgttaca ttaggagaaa agggggtgct cttgcttgat taagagagga
     1081 gatgttgtag ctctttattt gccttttcca agtattagta gcgatttggc tgtgaagaat
     1141 catatgtata tctgtattga caacagcatg actaaaaaca aagagttggt taaaaatcag
     1201 accttcaaac cagctctctt gaccagacgt ttggtcaaga actttatgat agaagagccg
     1261 gatctagctc gtaatccttt tacaagacca accttgattg acttagataa ggtatttatg
     1321 ttggataata cggtcattcc gacttcttat ctagccagac ggcgacgcaa tgtctcagaa
     1381 gaattgtacg aggaagtttt ggatcaccta gtccaaccac agctgatttc gctgaacaag
     1441 tctgagttta tgcaactcaa ttcaggaact tattaggagg tagaagatgg caaataaagc
     1501 agtaaatgac tttatactag ctatggatta cgacaaaaag aaactcttga cccatcaggg
     1561 agaaagtatt gaaaatcgtt tcatcaaaga gggtaatcag ctacccgatg agtttgttgt
     1621 tatcgaaaga aagaagcgga gcttgtcgac aaatacaagt gatatttctg taacagctac
     1681 caacgacagt cgcctctatc ctggagcact tctcgtagtg gatgagacct tgttagagaa
     1741 taatcccact cttcttgcgg tcgatcgtgc tccgatgact tatagtattg atttgcctgg
     1801 tttggcaagt agcgatagct ttctccaagt ggaagacccc agcaattcaa gtgttcgcgg
     1861 agcggtaaac gatttgttgg ctaagtggca tcaagattat ggtcaggtca ataatgtccc
     1921 agctagaatg cagtatgaaa aaatcacggc tcacagcatg gaacaactca aggtcaagtt
     1981 tggttctgac tttgaaaaga cagggaattc tcttgatatt gattttaact ctgtccattc
     2041 aggcgaaaag cagat
//
LOCUS       DAVFJR010000084         2053 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVFJR010000084 DAVFJR010000000
VERSION     DAVFJR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.085"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(133..1659)
                     /locus_tag="VU722_002146"
                     /pseudo
     CDS             complement(133..1659)
                     /locus_tag="VU722_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            1969..>2053
                     /locus_tag="VU722_002147"
     CDS             1969..>2053
                     /locus_tag="VU722_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1773026.1"
                     /translation="MRARHERRNRYSIRKFSVGVASVVVATF"
BASE COUNT          589 a          388 c          418 g          658 t
ORIGIN      
        1 tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagaatatta atgatagata
       61 aagtgagcct gggacaaaat agttctcaat cacaaaaaag ctagagattt ccaattgtgg
      121 aactctagct ttttaatttt gagtcgttct cttgttgtat tttaggaggt tattgaccat
      181 aagtaccaat cccatgtcaa ttctcagttg acgcttgcct ctcagattac atctcttgta
      241 acccaaacaa gcctttatct gcccaaagac aggttccaca tcaatcttgc gttgagcgaa
      301 aatctgtcta ccttggggag ataaaagcgc ctgacattct ttagctttca agttttgata
      361 gccttcgttc atatacagtc ccttttgagg ggctgattca ggttcgtcgg cgtagtaaac
      421 cttgatttct tgttgaaagt ctgtctgtgt tttctgatgt ttggtatggt gaaaacgata
      481 ataccagcca tcaggatgtg tatagctatc ctccttgtca ttatagtgcc aattccctaa
      541 gtttttagct gactatttat agcctctctt ttgttcctta tcaaacatgg catatttaat
      601 cagatggttt acctcctttt catctaaacg aaggaggtta tcttcactta catatccagc
      661 atctgcgaca actgtcttca agtcatgcgg ataggtttca aggaatggca gaagagtctt
      721 ggtatctgtc ggatttgaaa agacatcata gtgaagaaca aattggtttt ccgtagcgat
      781 ttgaagatta taagcagcct tgagttgacc atttttcata tggtcttctt tcatccgcat
      841 aaaagtggca tctggatcgg ttttggaaaa actgttacgc ccttgaaatg tctcctgata
      901 gttctcatat ttttcagcac gtactgaaaa atcctccttg actatacgca agactttctt
      961 gagtttccga cgttggtttt tacgttcatc cttcccttta atagctgtct cctcaatgtt
     1021 ctggttcagt ttttccaatt cttcttcaag gacttgagcg aatgcaagca actgctccga
     1081 ggagataggc tcttcttcct ccaacttaat ggcctgatgg ataaggggag tgatttcttc
     1141 ttgaaaatag acttgtatct gttcttgaag tttggcggca aacttgtccg ttgctttctt
     1201 ccacacgaaa ctatacttat tggcattagc ttcaatctta gtcccgtcaa taaacaagca
     1261 atctaaggtc acgaactctt ccatttttaa acgaagattg aggtcgatga aaagattgcg
     1321 aatgagttct tccatccctc cagctacacg aaaacgattg atggtgcgat agctgacaac
     1381 caactgccct gttaggtatt gcatagccag attttcaatc atcatttttt caatttttcg
     1441 tccagagaaa atcccttgtg aataggcaaa tagaagagca gatacaagca ttttagggtg
     1501 ataagacggg cgaccaaagg catgatagaa ggcgtggaaa tgacaatcct ccaaggtatt
     1561 caccactttt tcaatagtga agacgagatg gtcttgtggc aagaaggaac tgatttctag
     1621 tggtaaagtt gtttgatttg tgttatggtg aatatgcatg ggatagcctt tctaaatggt
     1681 ttattgtgca attctatttt accaagacta tcgcaaccat gcaaaaaagc aacggcaaat
     1741 ccgttgcttt ttttggagat aagagacttt tgtcccagac tccttgagtg aaaccaaagg
     1801 aatgaatcat aattatgaat ctagtaaagc attctccgag agccatttta aaggtcgagt
     1861 tggaattaaa caagaagaaa ctatctaaag caaagtctga ttcatattta tttaacattt
     1921 gtaggataga ctagtaaaaa aataaaaata tattggagga acttactcat gagagcaaga
     1981 catgaacgac ggaaccgata ttctattcgg aaatttagtg taggggtagc cagtgtagtg
     2041 gttgcgacct tct
//
LOCUS       DAVFJR010000085         1921 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVFJR010000085 DAVFJR010000000
VERSION     DAVFJR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.086"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            112..1845
                     /locus_tag="VU722_002148"
     CDS             112..1845
                     /locus_tag="VU722_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEU1773027.1"
                     /translation="MRVKQSKSKNTINYAIIKDIKVGNKRTSTIVENLGNHNTLLKEH
                     PDMEPLEWARLRAKELTEKEKEENKDFLITFSQNKQLKQNQLNEYHGGYLFLQDLYHQ
                     LDLPRINKEIQKRHRFNFSLDDILSRLIYGRILAPASKRSTLEFSKTLLEPKEFELQH
                     FYRALEVISNETEFIQEQTYQTSKKMTQRQTEVLYYDCTNFYFEIEAEDEEGLLRQYG
                     PSKEHRPNPIVEMGLFMDKQGIPLAFCIHPGNTNEQTTLKPLERKIVKEYKASKFVVC
                     TDAGLSSKANKMYNSFGERSYVTTQSIKKLKKEYRDWALDKSGWRMVGDKNPIFYNLD
                     ELEHREELKKQLFFKESPFYDEDLPNQRLIVTFSTKYQDYHRTIRERQIERASKLLGK
                     PSQATKKRQTDFKRFLKETSTTKEGEIAEKRILTLDEERIQEEAQYDGLYAVATNLDE
                     DIQTIVVINQRRWEIEESFRIMKQELRARPVYLSRSDRIQAHFTICFLALMIYRLLEK
                     QLGETVTCSELIQTLRNYKFKHLYGAGYLPTYTRTTITDQLHQAFGFQTDFEIISEKN
                     MKKIFKKTKSR"
BASE COUNT          704 a          362 c          341 g          514 t
ORIGIN      
        1 gtgaaaaact cctcataaag gttgatataa ggggattttc ttgtcaaatt tcaccgtttt
       61 ttatttgcgt acttttccgt actttgttat aatagagcga ggtataaaaa gatgagagtg
      121 aaacaatcaa agtcaaaaaa cactatcaac tacgctatta ttaaagacat caaggttgga
      181 aataaacgga cttctactat cgtagaaaac ttaggcaatc ataacacact cttaaaagaa
      241 catcctgata tggaacctct tgagtgggct cgtttacgtg ccaaggaatt aactgagaaa
      301 gaaaaagaag aaaataaaga tttcctcatt acctttagtc agaacaaaca gttaaaacaa
      361 aatcaattga acgaatatca tggaggctat ctcttcctac aagacctcta tcatcaacta
      421 gatttgccta gaattaacaa agaaatccaa aaacgacatc gttttaattt ctctctagat
      481 gatatcctat ctcgattgat ttatggacgg attctagctc ctgcttcaaa acgatccacc
      541 ctagaatttt caaaaacatt actcgaacct aaagaatttg aactccaaca tttttatcgg
      601 gctcttgaag ttatttctaa tgaaacagag tttatacaag aacaaaccta tcaaacttca
      661 aaaaagatga cccaacgaca gacagaagtt ctctactatg actgtactaa cttctatttt
      721 gaaattgaag ctgaagatga ggaaggactt ctgagacaat acggtccatc taaagaacat
      781 cgcccaaatc caattgtgga gatgggactc tttatggaca aacaaggaat tcccctagct
      841 ttctgtatcc accctggaaa tacaaatgaa caaactactc ttaaaccatt agaaagaaag
      901 attgtcaagg agtacaaggc ttcaaaattt gtagtctgta cagatgctgg actctcatca
      961 aaagccaata agatgtacaa ttcttttggg gaacgttcct atgtcacaac tcaatctatc
     1021 aagaagttaa agaaagaata cagagactgg gctttggata aaagtggttg gcgaatggtt
     1081 ggggataaga atcctatctt ttacaatctg gatgagctag agcacagaga ggaattaaaa
     1141 aaacagctct tctttaaaga atctcctttt tatgatgaag atttaccaaa tcaacgcttg
     1201 attgtgacct tttctactaa atatcaagac tatcatcgaa cgatacgaga gagacagatt
     1261 gaacgggcta gtaagttact gggcaagccc agccaagcta ccaagaagag acaaaccgat
     1321 tttaagagat ttctgaaaga aacaagtact accaaagaag gggaaatcgc cgagaaaagg
     1381 attctaactc ttgatgagga acggattcaa gaagaggctc aatatgatgg tctctacgcc
     1441 gtagccacta atctagatga agatatccag acaattgtag tcatcaatca aaggcggtgg
     1501 gaaattgaag agagttttcg tatcatgaag caggaactac gagccagacc cgtttatctc
     1561 agccgttcag ataggattca agcacatttc actatttgtt tcctagcact aatgatttat
     1621 cgtctcttgg aaaaacaact aggagaaaca gtcacctgtt cagaactcat ccaaacctta
     1681 cgcaattaca agttcaaaca tctttatgga gcaggatatc ttccaactta caccagaaca
     1741 actatcacgg atcaactcca ccaagcattt ggtttccaaa ctgattttga gattataagc
     1801 gaaaaaaata tgaaaaaaat ttttaagaaa accaaatcta gataaaaagt acgcattttt
     1861 taaaaagaga aaaagagctc cgaaaagctg tcatatcagt atttaggggc tctttgattt
     1921 c
//
LOCUS       DAVFJR010000086         1762 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVFJR010000086 DAVFJR010000000
VERSION     DAVFJR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.087"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(375..1571)
                     /gene="tuf"
                     /locus_tag="VU722_002149"
     CDS             complement(375..1571)
                     /gene="tuf"
                     /locus_tag="VU722_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU1773028.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT          497 a          344 c          353 g          568 t
ORIGIN      
        1 gtataatgct ttttgagttt agtctagtat tatactcttc gaaaatctct tcaaaccgcg
       61 tcagcttcgc cttgtcgtat agatgttact gacttcgtca gttctatcta caacctaaaa
      121 acagtgtttt gagcagtctg cagctaactt tctataacaa aatgaaataa gaacaagaca
      181 aatcaatcaa gacaatcaaa tcgatttcta acaatgtttt agaagtagat gtgtactatt
      241 ctagtttcaa tatattatag tttgctcttt gattttcatt gagtattagt tcaatatcta
      301 aaaaaagaac cttgccaagc aagattcttt tagtgtctga cttaaataat tgttcttctg
      361 ggaactaaat cgaattaagc ttcgatttct gtaaccatac ctgaaccaac agtacgtcca
      421 ccctcacgga tagagaatgt agtaccttgt tctacggcga ttgggtgaat caactcaacg
      481 tcgattgtca cgttatcacc aggcattacc atttcagtac ctgctggaag ttcgattgaa
      541 cctgtaacgt cagtagtacg gaagtagaat tgtggacggt agttgttgaa gaatggagtg
      601 tgacgtccac cttcttcttt agtaaggatg tagacttcac ctttgaattt agtgtgtggg
      661 ttgattgaac ctggtttagc gataacttgt ccacgttcga tttcatcacg ttgaacacca
      721 cgaagaagga cacctacgtt atctccagca agaccttcgt caagttgttt acggaacatt
      781 tcaacaccag taacaactgc tttttgagtt tcttctttga taccaacgat ttcgatttcg
      841 tcgttgactt taacgatacc acggtcgata cgtcctgaag caactgtacc acgtccagtg
      901 attgagaata cgtcctcgac tggaagaagc aatggtttat cagtgtcacg ttctggttct
      961 gggatatact catcaactgt gttcatcaat tccataacga tgtcttcgta tttagagtca
     1021 ccttcaagag ctttaagtgc tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg
     1081 tattctgaca ataggtcacg gatttccatt tcaaccaatt caagcaattc ttcgtcgtca
     1141 accaagtcaa ctttgttcat gaagacgata aggtgtttaa caccaacctg acgtgaaaga
     1201 aggatgtgct cacgagtttg tggcattggt ccgtcagttg aagctactac aaggatagct
     1261 ccgtccattt gagcagcacc agtgatcatg tttttaacgt agtccgcgtg tcctggagcg
     1321 tcgatgtgag cgtagtgacg tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg
     1381 ataccgcgtt cgcgttcttc tggagcagca tcgatagacg catagtcttt aggttggtta
     1441 actgatgaag gcaagcgacg tgccaaaaca gttgtgatag ctgcagttag ggtagtttta
     1501 ccgtggtcaa cgtgtccgat agtaccaatg ttaacgtgtg gtttactacg atcgtatttt
     1561 tcttttgcca tttgagtaaa agcctccaat aaaatatatt ttatagatag acagtaggca
     1621 atacagtcta actttcctta ctattttatc aaatttcagc taaattgcaa gtgttttaca
     1681 acgtttttgt gaattattct tggtaaaaat ttaactaatt aatagaaagt actaaataga
     1741 cttatccttc aaggagtttt ca
//
LOCUS       DAVFJR010000087         1748 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVFJR010000087 DAVFJR010000000
VERSION     DAVFJR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.088"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..1287
                     /locus_tag="VU722_002150"
     CDS             <1..1287
                     /locus_tag="VU722_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1773029.1"
                     /translation="SSGDLIYSINGLGRIRQLFTNQVVLGILDIGFVICILFYFLYID
                     FFVTIIALMLVVINLLLLLLTRKNLEQKSKSFVIAQNDLQNKQIEMIYSMMGIKMEGF
                     EVRTFKQWKGYLDKYLYRYRASELFSSVVNSLFSIITFISPFILLFIMLLPDNHLGNK
                     LGGIFAVYSLSSLLFGKINSIFDTIVAFYNSKTFLSRILEILGEETEINGVVKHDLNG
                     EIALKNVSFSYTRDSKKVLSNVSIEIKKGEKVAIVGSSGSGKSTLSKLLIGLFPASSG
                     SILFDDLDYNLLDKQYLRQQIGIVPQDMTLFNKTIHENIAGDISVSEEEMTKICKLVN
                     IHDEIMEMPMGYNTLVSEMGMNLSGGQRQRIILARALVKKPKIILLDEATSYLDNVNE
                     NEIMQKFKEQNITIIVIAHRLSTIIDSNQIFVMDKV"
     gene            complement(1423..>1748)
                     /locus_tag="VU722_002151"
     CDS             complement(1423..>1748)
                     /locus_tag="VU722_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU1773030.1"
                     /translation="FKDHPQVAKFAGLNWREKQSGNSNSQHTSLVNRGNRYLRYYLVE
                     AANSVRRYDDEYKDFYKKKYHEVPKHQHKRAIVLTARKFVRLVVVLLRNHQLYTPPRR
                     LMEDK"
BASE COUNT          565 a          245 c          333 g          605 t
ORIGIN      
        1 agtagtggtg atttaattta ttctataaat ggtttgggta gaattcggca attatttaca
       61 aatcaggttg tactaggaat attagatatt ggttttgtaa tttgtatttt gttttacttt
      121 ctatatattg attttttcgt gacgattatc gctcttatgt tagtggtaat aaatttgttg
      181 ttgcttctat tgactagaaa gaatttggaa caaaaaagta aatcttttgt gatagctcag
      241 aatgatctcc aaaataaaca aatcgaaatg atttattcta tgatgggaat aaaaatggaa
      301 ggatttgaag ttcgaacgtt taaacaatgg aaaggttatt tagataagta tctttataga
      361 tatagagcca gtgaattgtt ctcaagtgtt gttaattcgt tattttcaat tatcactttt
      421 atatctccat ttatcctatt atttattatg ttgttgccag ataatcattt aggtaataag
      481 ttaggtggaa tttttgcagt atattcttta tcatctctat tatttggtaa gattaatagt
      541 atttttgata cgattgtagc attctacaat agcaaaacat ttttatctcg gattttagag
      601 attttaggtg aagaaactga aataaatggt gtagtgaaac acgacttaaa tggggaaatc
      661 gcacttaaaa atgtttcatt ttcatatact agagatagta aaaaagtact ctctaatgtg
      721 tctattgaaa taaagaaggg ggaaaaggta gcaattgttg gctcttctgg atcaggtaaa
      781 agtacccttt ccaaattatt gataggttta tttccagcat cctcaggtag tattttattt
      841 gatgacttag attataattt gttggataaa cagtatcttc gtcaacaaat tggcattgtc
      901 ccacaagaca tgactttatt taataaaacc atacatgaga atattgctgg agacatctca
      961 gtctcagagg aagaaatgac aaaaatttgt aagttagtta atatccatga tgaaattatg
     1021 gaaatgccca tggggtataa tactttagtt tcagaaatgg gaatgaatct gtcaggaggg
     1081 caacgtcaga gaattatttt agcaagagcg ctagttaaga aacctaaaat aatactttta
     1141 gatgaagcca caagttatct agataatgtt aatgaaaacg agattatgca gaaatttaaa
     1201 gaacaaaata tcacaattat tgttattgca catcgacttt ctaccattat cgattctaac
     1261 cagatttttg taatggataa agtctagtgg taaaatgtca agcgaccccc cgctcaaagt
     1321 ttgaaaacta tttcaaaaaa agggtgcact aaagaagccc tactgaaaac gatgttttca
     1381 aactgttttc agtagatttt caaggagagg tgcagatata acttacttat cttccataag
     1441 cctccttggt ggcgtataga gttgatggtt gcgtagtagc acaaccacca gacgcacaaa
     1501 ttttctagcg gttagtacga tggctcgttt gtgttggtgt ttaggtactt catggtattt
     1561 cttcttatag aaatccttgt attcgtcatc atagcgcctt accgagttgg cggcttcaac
     1621 caggtagtag cgcagataac gattgcccct attcacaagc gaagtatgtt gtgagtttga
     1681 gttaccagat tgcttttctc tccaattcag accagcaaat tttgcgacct ggggatggtc
     1741 tttaaagc
//
LOCUS       DAVFJR010000088         1717 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVFJR010000088 DAVFJR010000000
VERSION     DAVFJR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.089"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            309..>1717
                     /locus_tag="VU722_002152"
     rRNA            309..>1717
                     /locus_tag="VU722_002152"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          474 a          361 c          501 g          381 t
ORIGIN      
        1 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactatgg
       61 tatgttgcgt caggaccact tgatgaaaaa aagtttaaaa aagcttaaaa atcttcaaaa
      121 aagtgttgac aagtgaaagt ggctgtgata tactaatata gttgtcgctt gagagaagca
      181 agtggcaaag acctttgaaa actgaacaag acgaaccaat gtgcagggcg ctacaacata
      241 agttgtagta ctgaacaatg aaaaaacaat aaatctgtca gtgacagaaa tgagtaagaa
      301 ctcaaacttt taatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat
      361 acatgcaagt agaacgctga aggaggagct tgcttctctg gatgagttgc gaacgggtga
      421 gtaacgcgta ggtaacctgc ctggtagcgg gggataacta ttggaaacga tagctaatac
      481 cgcataagag tagatgttgc atgacatttg cttaaaaggt gcacttgcat cactaccaga
      541 tggacctgcg ttgtattagc tagttggtgg ggtaacggct caccaaggcg acgatacata
      601 gccgacctga gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg
      661 aggcagcagt agggaatctt cggcaatgga cggaagtctg accgagcaac gccgcgtgag
      721 tgaagaaggt tttcggatcg taaagctctg ttgtaagaga agaacgagtg tgagagtgga
      781 aagttcacac tgtgacggta tcttaccaga aagggacggc taactacgtg ccagcagccg
      841 cggtaatacg taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg
      901 gttagataag tctgaagtta aaggctgtgg cttaaccata gtaggctttg gaaactgttt
      961 aacttgagtg caagagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata
     1021 tggaggaaca ccagtggcga aagcggctct ctggcttgta actgacgctg aggctcgaaa
     1081 gcgtggggag caaacaggat tagataccct ggtagtccac gctgtaaacg atgagtgcta
     1141 ggtgttagac cctttccggg gtttagtgcc gtagctaacg cattaagcac tccgcctggg
     1201 gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag
     1261 catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat ccctctgacc
     1321 gctctagaga tagagctttc cttcgggaca gaggtgacag gtggtgcatg gttgtcgtca
     1381 gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg
     1441 ccatcattta gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga
     1501 tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggctggta
     1561 caacgagtcg caagccggtg acggcaagct aatctcttaa agccagtctc agttcggatt
     1621 gtaggctgca actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg
     1681 cggtgaatac gttcccgggc cttgtacaca ccgcccg
//
LOCUS       DAVFJR010000089         1614 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVFJR010000089 DAVFJR010000000
VERSION     DAVFJR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.090"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            150..526
                     /locus_tag="VU722_002153"
                     /pseudo
     CDS             150..526
                     /locus_tag="VU722_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810398.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            691..990
                     /locus_tag="VU722_002154"
     CDS             691..990
                     /locus_tag="VU722_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU1773031.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1251..1591
                     /gene="tnpB"
                     /locus_tag="VU722_002155"
                     /pseudo
     CDS             1251..1591
                     /gene="tnpB"
                     /locus_tag="VU722_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          553 a          315 c          288 g          458 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaaagcg aatacagact
      121 atattgctcg ctatggcgta tatgcagtta tccctaatcc tgaacaaaaa caaattgttc
      181 ttgttcaaca accaaatggt gcttggttcc taccatgtgg agaaattgaa gcaggtgaaa
      241 atcatcagga agccctaaag cgtgagttga ttgaagagct tggtttcaca gcagaaattg
      301 gtacctatta cggacaagtt gacgaatatt tctattctcg tcatcgtgat acctactact
      361 acaatcctgc ctacctctat gaagcaactc ctttcaaaga agtacaaaag ccactagaaa
      421 actttaatca tattgcctgg ttcccgacga ggctatccaa aaccttaaac gtggtagcca
      481 taaatgggcc attgaatctt ggaaaaaaca gcataagatt ggctaatact cttcgaaaat
      541 aaaattcaaa ccacgtcagc gtcgccttac cgtactcaag tataggctgc ggctagcttc
      601 ctagtttgct ctttgatttt cattgagtat aaatcaagcg actttattca aaaagtgcta
      661 taatagaatt agaaaatcgg aggaaatatt atgaagctta tcaatacgac aaactcacac
      721 tcgcaacttg taaaaagtca gctagaaagt accgatgcaa cccttgttga ggtttattct
      781 gcagggaata cagatgttat ttttacccaa gctccgcttc actatgaaat cctcatctca
      841 aacaaacacc gtgctattcg tgagcctgaa atcgaaacca ttcaagaatt tttcttgaaa
      901 cgtaaaattg ataaggcctc tgttgatgaa gccaatatca agacactcta ctcagagaaa
      961 ttaattggaa tttcaatccc aatcaagtaa gaaaattgag taaaaactcg atttgagaga
     1021 aagtccaata agtctttcca taataaaacg catagtagca agagtttcta cacccactat
     1081 tatgcgtttt tatcattttg aaatctactg ctaatcaatg aagaagcaaa gatcaaacta
     1141 ggcagctagt tacaagttac gtaagcgcgt cataacaagg tatctatcct aattccccaa
     1201 cttccagtat actagataaa aaataattat cagaggaaaa gtattgtact atgatgattc
     1261 tactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg aggcagggaa
     1321 tagactcatt agcctatgta gttaaaaccc actttgaatt ggatcctttc tccggtcaag
     1381 tctttctctt ttgtggtgga cgtaaagacc gctttaaagc cctttactgg gatggtcaag
     1441 gattttggct actatataaa cgctttgaga acggaaaact gacttgacca agtacagaaa
     1501 aggatgtcaa agctctcaca ccagaacaag tagactggct tatgaagggc ttttctatca
     1561 ctccaaaaat aaatccatca gaaagtcgtg atttctattg aaatgaggac tttc
//
LOCUS       DAVFJR010000090         1460 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVFJR010000090 DAVFJR010000000
VERSION     DAVFJR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.091"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            161..>1460
                     /locus_tag="VU722_002156"
     CDS             161..>1460
                     /locus_tag="VU722_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HEU1773032.1"
                     /translation="MNKKKMILTSLASVAVLGAGFVASQPASVRAEGAQPAAEKAPTY
                     DDLLKLLKEFENDAIAAIGKRTDLTDEQKGAKRKEIKEFINKDEILKLVKDEVLTVDD
                     VLTELNAAADGASQIGRSVDKPYVGEYKNNVWAKDNANSGSEAQDLTDDQKQAINEEL
                     DKFAKRDDVQKAREALADLDEKAEKVSKKIELAKKSLETKNESVLKLKALYDEAVKSL
                     GESNELTRRLATEYSNNHDEFQALYESTQEQIEELKDYNEQISEGEETLILAIQNKIS
                     DLDDKIAEAEKKLADSQNGEGVEDYWTSGDEDKLEKLQAEQDELQAELDQLLDEVDGQ
                     EPAPEAPAEQPKPEKSAEQQAEEDYARRSEEEYNRLTQQQPPKAEKPAEEPTQPAPAP
                     EQPTEPTQPEKPVAPKTGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT          562 a          248 c          327 g          323 t
ORIGIN      
        1 aaaagggcaa aagtagtatc tttatctatt tttgggagta gaagcttatg atatagaaat
       61 ttgtaacaaa aatgtaatat aaaacacttg acaaatattt acggggggat ataattaata
      121 tatagtctga aaaggattat cagaaaagag gtaaatttag atgaataaga aaaaaatgat
      181 tttaacaagc ctagccagcg ttgctgtttt aggggctggt tttgttgcgt ctcagcctgc
      241 ttcggtgaga gcagaaggtg ctcaacctgc ggcagaaaaa gctccaactt acgatgattt
      301 actgaagctt ttgaaggagt ttgaaaatga tgcaattgca gcaattggca aacgcacaga
      361 cttaacagat gaacaaaaag gagcaaaacg taaggaaatc aaagaattca tcaataaaga
      421 tgaaattttg aaattggtca aagacgaggt tcttacagtg gacgatgtct tgacagaact
      481 aaacgcagca gctgatggag ctagtcaaat tggacgatca gttgataaac cttatgttgg
      541 ggaatataaa aacaatgttt gggctaaaga taatgctaat tcaggttccg aagctcaaga
      601 cctaacagat gaccaaaaac aagccattaa tgaagagtta gataaatttg ccaagcgtga
      661 tgatgtccaa aaagcaaggg aagctcttgc agacttggat gagaaagcgg aaaaggttag
      721 caaaaagatt gagctagcaa aaaaatctct tgagactaag aatgagtcag ttttgaagtt
      781 gaaagctctt tatgatgaag cagttaaatc acttggtgag tcaaatgagc ttactcgacg
      841 cctggcaaca gagtattcta ataatcatga tgagttccag gcgctctatg agtcaactca
      901 agaacaaatc gaagagttga aagactacaa cgaacaaatc tctgaaggag aagaaactct
      961 tatccttgcg attcaaaata aaatatcaga tctggatgat aaaatcgcag aagcggagaa
     1021 aaagcttgct gactcacaaa atggagaggg tgtagaagac tattggactt caggtgatga
     1081 ggacaaatta gaaaagcttc aagcagagca agatgaactt caagctgaat tggatcaatt
     1141 gttggatgaa gttgatggac aagaaccagc cccagaagca ccagctgaac aaccaaaacc
     1201 agagaagtca gcagaacaac aagctgaaga agactatgct cgtagatcag aagaagaata
     1261 taaccgcttg acccaacagc aaccgccaaa agctgaaaaa ccagctgaag agccaactca
     1321 accagcacca gccccagagc aaccaactga gccaactcaa ccagaaaaac cagtcgctcc
     1381 aaaaacaggt tggaaacaag aaaatggtat gtggtacttc tacaatactg atggttcaat
     1441 ggcgacagga tggctacaaa
//
LOCUS       DAVFJR010000091         1446 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVFJR010000091 DAVFJR010000000
VERSION     DAVFJR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.092"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VU722_002157"
     CDS             <1..550
                     /locus_tag="VU722_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1773033.1"
                     /translation="CEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWS
                     GFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVAD
                     SHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPP
                     LPEQSRIVDKIEQFFAHIDALI"
     gene            607..1404
                     /gene="psrA"
                     /locus_tag="VU722_002158"
     CDS             607..1404
                     /gene="psrA"
                     /locus_tag="VU722_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU1773034.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          504 a          207 c          261 g          474 t
ORIGIN      
        1 ttgtgaaata ccagaaagtt gggaatgggt gaggttaaac gatataacct cctacattca
       61 aagagggaag tctccaaaat attcaaatat tcctatatac cctgtgattg ctcagaaatg
      121 taatcaatgg tctggctttt ctattgactt agcaagattt attgatcccg aaacagttca
      181 tagttaccag aaagaaagat tactaagaga tggtgattta atgtggaatt caacaggtct
      241 aggtacgtta ggacgattag ctatttacca tgaaaataaa aatccttatg gctgggctgt
      301 tgcagatagc catgttacag ttataagagt cttatcggga gttattaatt gccatttcat
      361 ctataatttt ctttcctctc ctattgttca gtcagttatt gaagaaaaag cgtcgggtag
      421 tacaaaacaa aaagaattat taacgaaaac tataaaagaa tatttaatcc ccctcccacc
      481 ccttcctgaa caatccagaa tcgttgataa aatcgaacaa tttttcgccc atattgacgc
      541 actaatttag tataatagtt ttacgtgcgg tggaatttct atcaaacata agataggagt
      601 tttacgttga aagattttga attacatttg aagaaagctg gtttagctga aaatactgtg
      661 cgttcgtacc tttatggtgt tcgatttttc ttggagaatt acgaactcaa aatggaagat
      721 ttatttgaat acaaaggata tttattagac aattttaaac ctaaaactgt caatttgcga
      781 ctacaaggag taaataaata tctgactttt attggtcatg atgatttgaa attaaaattt
      841 gtcaaagtac agcaaaaacc gtttttagaa gatgtcatta gccacgctga ttaccttttt
      901 cttaaacgta gtttgaaaaa agatggtatt ttaaaatggc attttgtcgt ttggttttta
      961 ggtgcaactg gggctcgtgt aagtgaactt attaaactaa aagtagagca tgtagaaatc
     1021 ggttattttg acatttactc aaaaggtggt aaaattcgta gactgtacat tcctaaaaaa
     1081 ttaagaaata gttgtcttag ttggttagaa tcagaaaatc gccgaagtgg ttatttattt
     1141 ttgaataaat ttaacgaacc aattacagca agaggagttg ctcaacagtt aaaaaattat
     1201 gctgataaat acaaaatgaa tcctaaagta atttaccctc attcttttag gcatttattt
     1261 gctaagaatt ttttagcgaa gtataatgat attgccttgc ttgcagattt gatgggacac
     1321 gaaagtatag aaactactcg aatttatcta aggaaaacag ctactgaaca acaaaatatt
     1381 gtagataaaa ttgttaattg gtaaaaaata acaggtggtc aaactgacta cctgctattt
     1441 ttgtga
//
LOCUS       DAVFJR010000092         1137 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVFJR010000092 DAVFJR010000000
VERSION     DAVFJR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.093"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(190..273)
                     /locus_tag="VU722_002159"
     tRNA            complement(190..273)
                     /locus_tag="VU722_002159"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(237..239),aa:Leu,seq:caa)
     gene            complement(283..354)
                     /locus_tag="VU722_002160"
     tRNA            complement(283..354)
                     /locus_tag="VU722_002160"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(320..322),aa:Gln,seq:ttg)
     gene            complement(368..440)
                     /locus_tag="VU722_002161"
     tRNA            complement(368..440)
                     /locus_tag="VU722_002161"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(405..407),aa:His,seq:gtg)
     gene            complement(455..525)
                     /locus_tag="VU722_002162"
     tRNA            complement(455..525)
                     /locus_tag="VU722_002162"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(491..493),aa:Trp,seq:cca)
     gene            complement(530..610)
                     /locus_tag="VU722_002163"
     tRNA            complement(530..610)
                     /locus_tag="VU722_002163"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(574..576),aa:Tyr,seq:gta)
     gene            complement(623..695)
                     /locus_tag="VU722_002164"
     tRNA            complement(623..695)
                     /locus_tag="VU722_002164"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(660..662),aa:Phe,seq:gaa)
     gene            complement(699..772)
                     /locus_tag="VU722_002165"
     tRNA            complement(699..772)
                     /locus_tag="VU722_002165"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(736..738),aa:Met,seq:cat)
     gene            complement(783..872)
                     /locus_tag="VU722_002166"
     tRNA            complement(783..872)
                     /locus_tag="VU722_002166"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(834..836),aa:Ser,seq:tga)
     gene            complement(955..1028)
                     /locus_tag="VU722_002167"
     tRNA            complement(955..1028)
                     /locus_tag="VU722_002167"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(992..994),aa:Ile,seq:gat)
     gene            complement(1063..1133)
                     /locus_tag="VU722_002168"
     tRNA            complement(1063..1133)
                     /locus_tag="VU722_002168"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1099..1101),aa:Gly,seq:tcc)
BASE COUNT          326 a          294 c          248 g          269 t
ORIGIN      
        1 ctaaaaggac ttagccctgt acaatacaga actaaatcct ttgaataaat taattgtcta
       61 acttttgggg gtcagtacac ttttaatcat gtgcttttat atgaaattag taattattag
      121 taacaattcc aagaaatttc ttatggcata acaaaaagac aaggtttcta acccttgtct
      181 tttctactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
      241 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
      301 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
      361 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
      421 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
      481 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
      541 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
      601 ctacccttcc aaaatatata aatggcgcga gacggaatcg aaccgccgac acatggagct
      661 tcaatccatt gctctaccaa ctgagctacc gagccttatt gcgggagcag gatttgaacc
      721 tacgaccttc gggttatgag cccgacgagc taccgagctg ctccatcccg cgttaatata
      781 aaaggaggat gtgggattcg aacccacgca cgcttttaca cgcctgacgg ttttcaagac
      841 cgttcccttc agccggactt gggtaatcct ccaaaatagt ttatacggga acaagcccgt
      901 gtcctcttag tgaatagata atattccaat cccctagtaa tggactaaac actatgggca
      961 cgagtggact cgaaccaccg acctcacgct tatcaggcgt gcgctctaac cacctgagct
     1021 acgcgcccaa gtcaaaaact tggtacaaag aacaaagttc aaagcgggtg acgagaatcg
     1081 aactcgcgac aacagcttgg aaggctgtag ttttaccact aaactacacc cgctaaa
//
LOCUS       DAVFJR010000093         1049 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVFJR010000093 DAVFJR010000000
VERSION     DAVFJR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.094"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VU722_002169"
     CDS             <1..550
                     /locus_tag="VU722_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1773035.1"
                     /translation="ETSSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQFFE"
     gene            complement(498..1043)
                     /locus_tag="VU722_002170"
     CDS             complement(498..1043)
                     /locus_tag="VU722_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1773036.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGIRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKIEKLFEKVNQLWK"
BASE COUNT          373 a          166 c          153 g          357 t
ORIGIN      
        1 cgaaacatcc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccctgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagcttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaatt
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgcttagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aatgaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgctc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaat acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat ttattgaaaa aatatctttt
     1021 atttttataa caacccaatt cataggtat
//
LOCUS       DAVFJR010000094         1007 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVFJR010000094 DAVFJR010000000
VERSION     DAVFJR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.095"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..786
                     /locus_tag="VU722_002171"
     CDS             <1..786
                     /locus_tag="VU722_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEU1773037.1"
                     /translation="NWKIPCDAVKPTDGRYKTKESLILVLGDKLETLKKRRPLTEGEV
                     ERLNEEFLVEYTYNSNAIEGNTLTLRETDMVLRGLTIDRKSLKEHLEVIGHKDAFDYV
                     RQLVRENAPISEKIIKDIHYLVLADKKEDRGVYRRVPVRIMGAAHEPVQPYLIVPKME
                     ELLERYENSKEDIVTRLARFHIEFESIHPFIDGNGRTGRLLVNLELMKAGYPPIDIKF
                     TDRLKYYEAFDHYHLKDDLSAMADMFALYLNQKLDLYLSILDK"
BASE COUNT          367 a          140 c          193 g          307 t
ORIGIN      
        1 aattggaaaa taccatgtga cgcagtaaag ccgacagatg ggagatataa gactaaagaa
       61 tcactcattc tagtcttggg agataagtta gaaactctaa aaaaacgacg tcctttaact
      121 gaaggagaag tggaaagatt aaatgaagaa tttttagtag aatatacata caattctaat
      181 gctattgaag gaaatacact gactttacgt gaaacagaca tggttcttag aggacttaca
      241 attgaccgaa aatccttaaa agagcatttg gaggtcattg gacataaaga tgcttttgat
      301 tatgtaaggc aacttgttcg tgaaaatgct ccaatatctg aaaaaattat aaaagatatt
      361 cactatttgg ttttggcaga caagaaagaa gatagaggtg tgtatcgaag agttccagtt
      421 cgaattatgg gagcggctca tgaacctgtg caaccctatt taattgttcc taagatggaa
      481 gagttactgg aacgatatga aaatagcaaa gaagatattg ttactagact tgcccgtttt
      541 catattgagt tcgaatctat tcatcccttc attgatggaa atggaagaac agggaggttg
      601 ttggttaatt tggaactgat gaaagcaggt tatccaccta ttgatataaa atttactgat
      661 agattaaaat attatgaagc ttttgaccac tatcatttaa aggatgattt atcagccatg
      721 gcagatatgt ttgctctata tttgaatcag aaactagatt tatatttatc tattttagat
      781 aaatgagaat aaaagaattc cgtagaactt caaatttttg tcaatagagc tcttttaaga
      841 taatctaatc tatagactag gctggttcgg tatctttctg aaaaaatcct taacaaacgc
      901 cagcaaaaag ttagcgtttt tctgttcaaa tttgcgaaaa tagtatataa tagtactgtc
      961 tcaaaacttg tcttttgaca agcctgggaa caaaaagaaa aaaacat
//
LOCUS       DAVFJR010000095          959 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVFJR010000095 DAVFJR010000000
VERSION     DAVFJR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.096"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(499..>959)
                     /locus_tag="VU722_002172"
     CDS             complement(499..>959)
                     /locus_tag="VU722_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEU1773038.1"
                     /translation="NAPISEKIIKDIHYLVLADKKEDRGVYRRVLVRIMGAAHEPVQP
                     YLIVSKMEELLERYENSKEDIVTKLARFHIEFESIHLFIDGNGRTGRLLLNLELMKAG
                     YPPIDIKFTDRLKYYESFDHYHFKGRFVSYGRHVCSIFKSETRSIFIYFR"
BASE COUNT          292 a          170 c          140 g          357 t
ORIGIN      
        1 tatcgataca ttctattcaa aaaattagga tgactgtcta gtaggcttag caatttatta
       61 cttttgttat attatttagg aaaggacgtt tcatgtttac atctagcgga aaaatatcgt
      121 ctatcccact agcacagtct aacccagtct aacccagtct aactattata tcataattca
      181 tagagatact tacttactta cttacttact tacttactta cttacttact tacttactta
      241 ctcatggtag ctgattttat caataattgt aagctattta tctttgaatg tcagaattat
      301 taaattttta ttacacgctg gtttttgcta tcgtgagaag ggagcgtttg gtttttggct
      361 ctgcgtcctt ggtttcatat cgattctgga tgctttttgt gttatgtgtg aataattggg
      421 gctatagatt atcagattat cttacaagag atctattgac aaagacttga agggattttg
      481 acattctctt attctcattt atctaaaata gataaatata gatctagttt ctgatttaaa
      541 tatagagcaa acatgtctgc cataactgac aaatcttcct ttaaaatgat agtgatcaaa
      601 agattcataa tattttaatc tatcagtaaa ttttatatcg ataggtggat agcctgcttt
      661 catcagttcc aaattaagca acaacctccc cgttcttcca tttccatcaa tgaagagatg
      721 aatagattcg aactcaatat gaaaacgggc aagtttagta acaatatctt ctttgctatt
      781 ttcgtatcgt tccagtaact cttccatctt agaaacaatt aaatagggtt gcacaggttc
      841 atgggctgct cccataattc gaactagaac tcttcgatac acacccctat cttctttctt
      901 atctgccaaa accaaatagt gaatatcttt tataatcttt tcagatattg gagcatttt
//
LOCUS       DAVFJR010000096          844 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVFJR010000096 DAVFJR010000000
VERSION     DAVFJR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.097"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..469
                     /locus_tag="VU722_002173"
     CDS             <1..469
                     /locus_tag="VU722_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1773039.1"
                     /translation="KNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTELID
                     IICQKFNVSYVDIVGEDKMFNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISID
                     DESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            469..>844
                     /locus_tag="VU722_002174"
     CDS             469..>844
                     /locus_tag="VU722_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU1773040.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPK"
BASE COUNT          300 a          113 c          175 g          256 t
ORIGIN      
        1 aaagaacata aaatccttac gtaaaacaca tgacttaaca caacccgaat ttgcacgaat
       61 tataggaatt tctcgaaata gcttgagtcg ttatgaaaat ggaactagtt cagtctctac
      121 ggaactaata gatatcattt gtcagaagtt taatgtatct tatgtcgata ttgtaggaga
      181 agataaaatg ttcaatcctg ttgaagatta tgaattgact ttgaaaattg aaattgtgaa
      241 agaaagaggt gctaatctat tatctcgact ctatcgttat caagatagtc agggaattag
      301 cattgatgat gaatctaatc cttggatttt aatgagtgat gatctatctg acttgattca
      361 tacgaatatc tatttagtag aaacttttga tgaaatagag agatatagtg gctatttgga
      421 tggaattgaa cgtatgttag agatatctga aaagcggatg gtagcttaat ggaaatccaa
      481 gattatactg atagtgaatt caaacatgct ttagcaagga atcttcgttc actgacaaga
      541 ggaaaaaagt ccagtaagca acctatagcg attttgcttg gagggcaaag tggtgctggt
      601 aagactacaa ttcatcgtat taaacagaaa gaatttcaag gaaatattgt tatcatagat
      661 ggtgatagtt ttcgttctca gcatccacac tatttagaac tgcagcaaga atatggcaaa
      721 gatagcgttg aatacaccaa agattttgca ggaaaaatgg tagagtcttt agtaacaaaa
      781 ttgagtagtt tgggatacaa tcttttgatc gagggaactt tacgaacgat tgacgttcca
      841 aagg
//
LOCUS       DAVFJR010000097          795 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVFJR010000097 DAVFJR010000000
VERSION     DAVFJR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.098"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            1..378
                     /locus_tag="VU722_002175"
                     /pseudo
     CDS             1..378
                     /locus_tag="VU722_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
BASE COUNT          205 a          168 c          177 g          245 t
ORIGIN      
        1 gacttccttc ctcgtgtaca tggttcaggt ctctttactc gtgggcaaac tcaagctctt
       61 tcagtcttga ccttggctcc gatgggagaa actcaaatca ttgatggttt ggatccagag
      121 tacaagaaac gctttatgca ccactataac ttccctcaat attctgtagg ggaaacaggc
      181 cgttacggtg cgccaggtcg tcgtgaaatc ggtcacggtg ctcttggtga gcgtgctctt
      241 gctcaagtct tgccaagctt ggaagaattc ccatacgcta tccgtctagt agcagaagtt
      301 ttggaatcaa acggttcttc atctcaagct tctatctgtg cgggaactct tgcccttatg
      361 gctggtggtg tgccaattac tcttagaaaa tctcttcaaa ccacgtcaac gtcgccttgc
      421 cgtgcgtatg gttactgact tcgtcagttc tattcacaac ctcaaaacag tgttttgagc
      481 aacctgcggc tagtttccta gtttgctctt tggttttcat tgagtataac acattgttag
      541 aagttggttt aaattcccta atcaatttgt tcacatttac cttcgatata ttatatccca
      601 tagttatagt ggaaaacact attgttcgga taaatggtag atgttattcc gactcccttg
      661 ctattgttcc gacaaggtga tataatgtga cagaacggag ggataaaaaa tgtatattac
      721 agcgaaagag gccgctaaaa agtgggggat atctgacaga agggtaagaa ttttgtgctc
      781 agaagggaag attca
//
LOCUS       DAVFJR010000098          763 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVFJR010000098 DAVFJR010000000
VERSION     DAVFJR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.099"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            185..>763
                     /locus_tag="VU722_002176"
     CDS             185..>763
                     /locus_tag="VU722_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU1773041.1"
                     /translation="MSSSKTSSVSYFYFAFDVLGILIFVGKAYNFINPKGIKMAKQVF
                     QTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAVMSKKMATGDFFPLQVNYEEK
                     MYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENA
                     SAPMAAMFGSSLALSISDIPFDGPIAGVQVGYV"
BASE COUNT          198 a          149 c          174 g          242 t
ORIGIN      
        1 cttggtatct tgatgacttg aattttggtc tcatttctta ggaaaaaaga taagcttcct
       61 agcactcgtc gagtgcgacg tcaccttcct atttttctac agaaatgttc ggcaagccga
      121 accgtccaaa atatcttgtg taattgaaca cggccgaaaa gctgtgtaaa aaagataaac
      181 tgtcttgtct tcatcgaaga cttcgtcagt ttcctatttt tactttgctt ttgacgtcct
      241 tggtatcttg atctttgtag gcaaggcgta taatttcatc aatccaaagg ggattaaaat
      301 ggcaaaacaa gtgtttcaaa cgacttttgc gggtcgtgag ttaattgtag agactggtca
      361 ggttgctaag caagcaaatg gctctgttgt tgtacgttac ggtgagtcaa ctgtcttgac
      421 tgctgccgtt atgtctaaga aaatggcaac tggggatttc ttcccactcc aagtcaacta
      481 cgaagaaaaa atgtatgcgg ctgggaagtt tcctggtggc tttatgaaac gtgaaggacg
      541 tccttcaaca gatgcgacct tgacagcgcg tttgattgac cgtccgattc gtcctatgtt
      601 tgcggaaggt ttccgtaatg aagtccaagt catcaataca gtgctttctt atgatgaaaa
      661 tgcatctgca ccaatggctg ctatgtttgg ttcatctttg gcactgtcta tttcagatat
      721 tccatttgac ggaccaattg ctggggtaca agtgggatat gta
//
LOCUS       DAVFJR010000099          692 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVFJR010000099 DAVFJR010000000
VERSION     DAVFJR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.100"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VU722_002177"
     tRNA            complement(74..147)
                     /locus_tag="VU722_002177"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VU722_002178"
     tRNA            complement(157..242)
                     /locus_tag="VU722_002178"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VU722_002179"
     tRNA            complement(250..321)
                     /locus_tag="VU722_002179"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VU722_002180"
     tRNA            complement(344..416)
                     /locus_tag="VU722_002180"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VU722_002181"
     tRNA            complement(435..516)
                     /locus_tag="VU722_002181"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VU722_002182"
     tRNA            complement(522..594)
                     /locus_tag="VU722_002182"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VU722_002183"
     tRNA            complement(619..691)
                     /locus_tag="VU722_002183"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVFJR010000100          638 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVFJR010000100 DAVFJR010000000
VERSION     DAVFJR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.101"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            1..638
                     /locus_tag="VU722_002184"
                     /pseudo
     CDS             1..638
                     /locus_tag="VU722_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          196 a          117 c          145 g          180 t
ORIGIN      
        1 agagattata gaacttttag actgtaatca aacaatgatt tggcgaaatg taaaaaaata
       61 tgaggagttc ggactcgact ctctccttca agaaacacgt ggtggtcgta accatgcata
      121 tatgacagtt gaggaagaga aagcctttct tgcccgccat ttgaaggcta cagaggcagg
      181 agaatttgtt acaattgatg ccttatttca ggcttataaa aaggagttag gtcgttccta
      241 cacacgtgat gccttctatc aactgttgaa gcgccatggt tggcgaaata ttatgccacg
      301 tccagaacat cttaggaaag cagacgctca aaccattgtc gcgtctaaaa ataaaatctc
      361 aattcaagaa gacgagaaag cgctttaaaa ccagtagacg ttttcgtaag gttcgcttga
      421 tgtaccaaga tgaggctggt ttcggtagaa tcagtaaact gggatcttgt tgggctccaa
      481 taggagtagg tccacatatc catagtcact atatacgaga atttcgctat tgttatggag
      541 ctgttgatgc ccatacaggc gaatcatttt tcttaatagc tggtggatgt aatactgagt
      601 ggatgaacgc ctttttagaa gagctttcac aagcttat
//
LOCUS       DAVFJR010000101          559 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVFJR010000101 DAVFJR010000000
VERSION     DAVFJR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.102"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            complement(<1..455)
                     /locus_tag="VU722_002185"
     CDS             complement(<1..455)
                     /locus_tag="VU722_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU1773042.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          151 a          133 c           71 g          204 t
ORIGIN      
        1 ttaaacacaa tgcgtaagtc tcttaatact ctttgacgcc ctcgaaatcg ttcattgctt
       61 aagacgcgtt ctagttcttc ttgtttctct ttactttgtt tgtttctata atctcttagt
      121 gtttcatgaa agagataata atcatctagc cagagacccc cctcacttat acgatgactg
      181 atctctccca cttcttcata gggttcttta tcgtatctac gcttctgact ttcctgctta
      241 cggatatagt ctaaaattcg atttcgaaac ttggttttga aatatttcct taaacgtgga
      301 atatcgtcta ccagtccttc ttctctacta atcaattcat gtaagcagag catgccttct
      361 tggtcccaat ccgacaattc ccataaatga aggtaatatt catttctaca cttatacaca
      421 gtcccttgga cttcttcata caattcttta atcataattt tcccctttct agatacagtc
      481 taacagatta gaaaacacat ttgttacatt ttctccattc tgttcccttt agctcctaaa
      541 ctgcacaaaa aaaagaggc
//
LOCUS       DAVFJR010000102          528 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVFJR010000102 DAVFJR010000000
VERSION     DAVFJR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.denovo.103"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            <1..>528
                     /locus_tag="VU722_002186"
     CDS             <1..>528
                     /locus_tag="VU722_002186"
                     /inference="COORDINATES: protein motif:HMM:NF019192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU1773043.1"
                     /translation="KLKAAKDLLVPKSDNTGLTTAKNALDTERNKAVDTTGKTPASVA
                     AYNDAKQKAQEASDAAQTVLNNPNATEQQIQDEITKVNAAKEKLGKAEAGLTTAATAQ
                     AKQELTTAKEGLEEPVSTDGMTPDSIKAYEAAKKEAAQAVADAKAAAQAAEAKGENAT
                     EAEVNEAKAKVDAAK"
BASE COUNT          241 a           98 c          125 g           64 t
ORIGIN      
        1 aaaaattaaa agcagctaaa gatctgttag taccgaagtc agacaataca ggtttaacaa
       61 cagctaagaa tgcattagat acagagcgta ataaggctgt agatacaaca ggtaagacac
      121 cagcgtcagt agcagcgtac aatgatgcaa aacaaaaagc gcaagaagca tcagacgcag
      181 cgcaaacagt gttaaacaat ccaaacgcaa cagaacaaca aatccaagat gaaattacga
      241 aagtaaatgc agcgaaagag aagttaggaa aagcagaagc aggattaaca acagcagcaa
      301 cagcgcaagc aaaacaagag ttaacaactg caaaagaagg attggaagag ccagtatcaa
      361 cagacggaat gacaccggac agtataaaag catacgaagc agctaagaaa gaagcagcgc
      421 aagcagtagc agatgcaaaa gcagcagcgc aagcagcaga agctaaaggt gaaaacgcga
      481 cagaagcaga agtaaatgaa gcgaaagcga aagtagacgc agctaaag
//
LOCUS       DAVFJR010000103        41210 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 2013-452
            SAMEA3905315-rid19719603.guided.014, whole genome shotgun sequence.
ACCESSION   DAVFJR010000103 DAVFJR010000000
VERSION     DAVFJR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3905315
            Sequence Read Archive: ERR1443307
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928578.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:35:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,231
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,010
            CDSs (with protein)               :: 2,010
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 174
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 174
            Pseudo Genes (frameshifted)       :: 77 of 174
            Pseudo Genes (incomplete)         :: 76 of 174
            Pseudo Genes (internal stop)      :: 56 of 174
            Pseudo Genes (multiple problems)  :: 30 of 174
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3905315-rid19719603.guided.014"
                     /strain="2013-452"
                     /db_xref="taxon:1313"
     gene            111..1370
                     /locus_tag="VU722_002187"
     CDS             111..1370
                     /locus_tag="VU722_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU1773044.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1446..1581
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1620..2120
                     /locus_tag="VU722_002188"
     CDS             1620..2120
                     /locus_tag="VU722_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU1773045.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARSLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2196..2564
                     /gene="rplL"
                     /locus_tag="VU722_002189"
     CDS             2196..2564
                     /gene="rplL"
                     /locus_tag="VU722_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU1773046.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DATDAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2766..2939
                     /locus_tag="VU722_002190"
     CDS             2766..2939
                     /locus_tag="VU722_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773047.1"
                     /translation="MTKELQSSRHIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            2936..3715
                     /locus_tag="VU722_002191"
     CDS             2936..3715
                     /locus_tag="VU722_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU1773048.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQDENDTAPVSHLAPSETEVSETKYSE
                     TDSLFIEDEEERNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            3814..5172
                     /gene="dcm"
                     /locus_tag="VU722_002192"
     CDS             3814..5172
                     /gene="dcm"
                     /locus_tag="VU722_002192"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU1773049.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            5156..5605
                     /locus_tag="VU722_002193"
     CDS             5156..5605
                     /locus_tag="VU722_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773050.1"
                     /translation="MKALNRESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            5598..5978
                     /locus_tag="VU722_002194"
     CDS             5598..5978
                     /locus_tag="VU722_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773051.1"
                     /translation="MIDLYLSKNNHRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            5991..6224
                     /locus_tag="VU722_002195"
     CDS             5991..6224
                     /locus_tag="VU722_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1773052.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            6227..6814
                     /locus_tag="VU722_002196"
     CDS             6227..6814
                     /locus_tag="VU722_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1773053.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFISLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLSVYVLFLL"
     gene            7191..7505
                     /locus_tag="VU722_002197"
     CDS             7191..7505
                     /locus_tag="VU722_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU1773054.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            7521..7907
                     /locus_tag="VU722_002198"
     CDS             7521..7907
                     /locus_tag="VU722_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU1773055.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            7936..9318
                     /locus_tag="VU722_002199"
     CDS             7936..9318
                     /locus_tag="VU722_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU1773056.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHL
                     EKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYD
                     KLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKE
                     DLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKE
                     NTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGM
                     MFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQA
                     TCEAEVAGVD"
     gene            9321..9473
                     /locus_tag="VU722_002200"
     CDS             9321..9473
                     /locus_tag="VU722_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1773057.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            9496..10701
                     /locus_tag="VU722_002201"
     CDS             9496..10701
                     /locus_tag="VU722_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU1773058.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            10744..10965
                     /locus_tag="VU722_002202"
     CDS             10744..10965
                     /locus_tag="VU722_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773059.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            11082..11579
                     /locus_tag="VU722_002203"
     CDS             11082..11579
                     /locus_tag="VU722_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU1773060.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            11554..12060
                     /locus_tag="VU722_002204"
     CDS             11554..12060
                     /locus_tag="VU722_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1773061.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            12044..14491
                     /locus_tag="VU722_002205"
     CDS             12044..14491
                     /locus_tag="VU722_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1773062.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            14494..16671
                     /locus_tag="VU722_002206"
     CDS             14494..16671
                     /locus_tag="VU722_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU1773063.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            16668..17669
                     /locus_tag="VU722_002207"
     CDS             16668..17669
                     /locus_tag="VU722_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU1773064.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            17666..18601
                     /locus_tag="VU722_002208"
     CDS             17666..18601
                     /locus_tag="VU722_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU1773065.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            18845..18961
                     /locus_tag="VU722_002209"
     CDS             18845..18961
                     /locus_tag="VU722_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU1773066.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18977..20896
                     /gene="tet(M)"
                     /locus_tag="VU722_002210"
     CDS             18977..20896
                     /gene="tet(M)"
                     /locus_tag="VU722_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU1773067.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            21015..21182
                     /locus_tag="VU722_002211"
     CDS             21015..21182
                     /locus_tag="VU722_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU1773068.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(21242..21379)
                     /locus_tag="VU722_002212"
                     /pseudo
     CDS             complement(21242..21379)
                     /locus_tag="VU722_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            21795..21878
                     /locus_tag="VU722_002213"
     CDS             21795..21878
                     /locus_tag="VU722_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEU1773069.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            22003..22740
                     /gene="erm(B)"
                     /locus_tag="VU722_002214"
     CDS             22003..22740
                     /gene="erm(B)"
                     /locus_tag="VU722_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU1773070.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            23095..23649
                     /locus_tag="VU722_002215"
     CDS             23095..23649
                     /locus_tag="VU722_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1773071.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            23653..26571
                     /locus_tag="VU722_002216"
     CDS             23653..26571
                     /locus_tag="VU722_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HEU1773072.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(26645..26866)
                     /locus_tag="VU722_002217"
                     /pseudo
     CDS             complement(26645..26866)
                     /locus_tag="VU722_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            27371..27793
                     /locus_tag="VU722_002218"
     CDS             27371..27793
                     /locus_tag="VU722_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU1773073.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            27790..28020
                     /locus_tag="VU722_002219"
     CDS             27790..28020
                     /locus_tag="VU722_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1773074.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            28481..28684
                     /locus_tag="VU722_002220"
     CDS             28481..28684
                     /locus_tag="VU722_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU1773075.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            28766..29983
                     /locus_tag="VU722_002221"
     CDS             28766..29983
                     /locus_tag="VU722_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1773076.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            30253..30843
                     /locus_tag="VU722_002222"
     CDS             30253..30843
                     /locus_tag="VU722_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEU1773077.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            30843..31679
                     /locus_tag="VU722_002223"
     CDS             30843..31679
                     /locus_tag="VU722_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEU1773078.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            31962..32261
                     /locus_tag="VU722_002224"
     CDS             31962..32261
                     /locus_tag="VU722_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773079.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            32251..32739
                     /locus_tag="VU722_002225"
     CDS             32251..32739
                     /locus_tag="VU722_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773080.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            32739..34616
                     /locus_tag="VU722_002226"
     CDS             32739..34616
                     /locus_tag="VU722_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU1773081.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            34637..34879
                     /locus_tag="VU722_002227"
     CDS             34637..34879
                     /locus_tag="VU722_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1773082.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            34896..35750
                     /locus_tag="VU722_002228"
     CDS             34896..35750
                     /locus_tag="VU722_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU1773083.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            35804..36163
                     /locus_tag="VU722_002229"
     CDS             35804..36163
                     /locus_tag="VU722_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU1773084.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            36156..38471
                     /locus_tag="VU722_002230"
                     /pseudo
     CDS             36156..38471
                     /locus_tag="VU722_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            38483..41188
                     /locus_tag="VU722_002231"
     CDS             38483..41188
                     /locus_tag="VU722_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1773085.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFVGARRF"
BASE COUNT        13695 a         7031 c         8447 g        12037 t
ORIGIN      
        1 gttttgaggt tgcagataga actgacgaag tcagtaacca cacctacggc aaagtgaatc
       61 tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa ggagcctaca atgaaagtct
      121 ttcagcatgt aaatatcgtg acttgtgatc aagatttcca tgtttatctt gatggaatct
      181 tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga taagccagcg tttttagagc
      241 aagctgagca gattatagac tatcagggag cttggattat gcctggtttg gtcaattgtc
      301 acacccattc tgcaatgaca ggtctgagag ggatccgaga tgacagcaat ctccatgaat
      361 ggctcaatga ctatatctgg ccagcagaat ctgagtttac tcccgacatg actaccaatg
      421 cggtcaaaga agccctgaca gagatgctcc agtcaggaac aacaaccttt aacgatatgt
      481 ataatcccaa tggtgtggat attcagcaaa tttatcaggt ggtgaaaact tccaagatgc
      541 gttgttattt ttctccgact ctcttttctt cagagacaga aacaactgct gagactataa
      601 gcagaactcg atccatcata gacgaaatct taaaatataa aaatccaaat ttcaaggtta
      661 tggtagcacc tcattctccg tatagctgca gtagagactt gctggaagcg agtttggaaa
      721 tggcaaaaga gctaaatatt ccgctccatg tccatgtggc ggagaccaag gaggagtcag
      781 gaattatcct caaacgatac ggcaaacgcc cccttgcttt tcttgaagaa ctgggttatt
      841 tagatcatcc gtccgtattt gctcacgggg tcgaattaaa cgagagagaa attgaacgct
      901 tggcatcttc tcaagtggct atcgcccaca atcctatcag taacctcaaa ctggcatcag
      961 gaattgctcc aattatccag ctccaaaaag cgggagtagc agtcggaatt gcgactgact
     1021 cggttgcttc caataacaat ctagatatgt ttgaggaagg aaggactgca gctcttcttc
     1081 agaagatgaa aagtggggat gccagccagt ttccaatcga aacagctctc aaggtactga
     1141 caatcgaagg ggctaaggcc cttggaatgg aaaatcagat aggaagtctg gaagtcggca
     1201 agcaagcaga ttttctggtc attcaaccac aagggaaaat tcatctccaa cctcaggaaa
     1261 atatgctgtc tcacctggtt tatgcagtta aatctagtga tgtagatgat gtttatatcg
     1321 ccggagaaca ggttgttaag caaggtcaag tcctgacagt agaactttaa aagaaaaatc
     1381 acgaaaaatt ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac tatgctatac
     1441 ttatatacgg tttaaaaaaa ctgcctaaga cagtagggga gctcgactca taaatatcct
     1501 accgaggaca agacgtatca tgtaaaaaga agcgtattgt actttcgtgt ctaggtttgg
     1561 gcgcgttttt ctttttgaaa aattccccaa gcaaaataat tacggaggtg aacacactaa
     1621 tgagtgaagc aattattgct aaaaaagcgg aactagttga cgtagtagct gaaaaaatga
     1681 aagctgctgc atctatcgtc gttgtagacg ctcgtagttt gacagttgag caagatacag
     1741 ttcttcgtcg tgagcttcgt ggaagcgaag ttgagtataa agttattaaa aactcaatct
     1801 tgcgtcgtgc agctgaaaaa gctggtcttg aagatcttgc atctgtattt gttggaccat
     1861 ctgcagtagc attttctaat gaagatgtta tcgcaccagc gaaaatcttg aacgactttt
     1921 ctaaaaacgc tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct gtcgcatcta
     1981 aagaagagat tcttgcactt gcaactcttc caaaccgcga aggacttctt tctatgctcc
     2041 tttctgtact tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg gttgcagaaa
     2101 gcaaagaaga cgcggcttaa tcttaagcta catagcgtag cctagctacg aaaaaaacta
     2161 ttataaaatt taaaacttat ttggaggaaa taacaatggc attgaacatt gaaaacatta
     2221 ttgctgaaat taaagaagct tcaatccttg aattgaacga ccttgtaaaa gctatcgaag
     2281 aagaatttgg tgtaactgca gctgctcctg tagctgttgc tgcagctgat gcaactgatg
     2341 ctggtgctgc taaagattca ttcgacgttg aattgacatc tgcaggcgac aaaaaagttg
     2401 gtgttatcaa agttgtacgt gaaatcactg gtcttggtct taaagaagct aaagaacttg
     2461 ttgacggtgc accagcactt gttaaagaag gcgttgcaac tgcagaagct gaagaaatca
     2521 aagctaaatt ggaagaagct ggagcttcag ttactcttaa ataagaggca tataccaatt
     2581 agaaatcgga atactatagt atcagccttt tagaatcgtg aacacatttt agaaactgat
     2641 aaattaattt agtttcctac caaaaaccct accaaaaatt aatttggcag ggtttttctt
     2701 tttaacaaat ttatcgtgga gaacaattga atattgttct ccttttttta ttttcaggag
     2761 gaaaaatgac aaaagaatta caatcatcac gccatattgt catttcattt ttagtacgtg
     2821 aaatgggaat tgacattgtt gaggccatct ctcttatggc tgaattagaa aaaagtggct
     2881 tggttcgctt ggaatcaagt ggagatttaa tactcaaaga acttggagga gcgctatgaa
     2941 acgaattacc gcaaatcaat accaaacttc agaacggtat tataaattac ctaaaattct
     3001 ttttgaagat gagaaatata tggatatgaa actagaagta aaggtggctt attctatttt
     3061 aaaagatcgt ttagaattat ctctcagtcg tggttggata gatgaagaag gagcggttta
     3121 tttagtattt tctaattcta aactgatgaa gctattaggt tgttcgaagt caaaattact
     3181 gtccatcaaa aaaactctta aagaatatga cttaattgat gaagttcaac agtcttcaag
     3241 tgagaagggg agactagcta ataagattta tttaggggaa ttatcttcta ccccagtagg
     3301 taattcaaac aggcctagtg ttaaaaaaag actagggcag gatgaaaatg atacggcccc
     3361 cgtctcacat ttagccccta gtgagactga agttagtgag actaaatata gtgagactga
     3421 ttctttattt attgaggatg aggaggagag gaatactcaa cctatcttga aaagaaaagt
     3481 agaaaaggtc acaaaatatg atcgagatta tatttgggga ttggtacaag atcaatttag
     3541 acgagagggg ttttctgaaa cagccagtga aattgctatg actgattttg agagaatcta
     3601 tcagtatgct cttgacaatg ttcgctttgt tagacgtgcg gaagtacttg ctgaatttgt
     3661 gtttaatggc ttgtattctg tttggaacaa ccgtgttaga aaaggaggtg gttaaatgtc
     3721 gccaatcgag tggatattag ttatgctcat tgtcatttca agtggagtga cagttctgac
     3781 aatgatagtc gataagaaag gggtgataaa gaattgagat ttattgattt attttcaggt
     3841 atcggtggct ttcgacttgg aatggaaagt gttggacacg agtgtattgg attttgtgag
     3901 atcgataaat ttgctagaga atcttataag tccatttttc aaacggaagg agaaatagaa
     3961 tttcatgaca tacgagatgt ttcagatgac gaatttaaaa aacttagagg gaaagtcgat
     4021 gtcatctgtg ggggattccc ttgtcaagca ttttcaatcg caggaagacg attgggattt
     4081 gaagatacta gaggaacttt gttctttgaa attgctcggg cggccaaaca aatccaacca
     4141 cgttttcttt ttcttgaaaa tgttaaaggc ctactcaatc acgataaggg acggacgttc
     4201 accacaatcc ttaccacact tgatgagttg gggtttgatg ttgagtggca ggtgcttaac
     4261 agtaaggatt ttggcgttcc ccaaaacaga gagagggtgt ttattatcgg acattctaga
     4321 aagaaaggta cccgactcct atttcctttc agacgagaag gtcaagcaac taactctgag
     4381 actttgaaag cactaggaaa tttgaatcca tcaaaaagtg gaatgagtgg taaagtctat
     4441 tattcagaag gtcttgcgcc aaccttagtt cgtggaaaag gagaaggatt taaagttgcg
     4501 attccttgta tgacaccaga cagattagaa aagagacaaa atggtagacg tttcaaggat
     4561 aatcaagagc caatgtttac tttaaatact caggatcgcc atggtattgt cgttgttgga
     4621 gatttaccaa ctagctttaa ggaaactggt cgcgtctatg gaagtgaggg gctatctcca
     4681 acactgacta cgatgcaagg tggagataaa atccccaaaa tactgattcc agaaccaatc
     4741 caatttctaa aagtccgaga ggcaacgaaa aaaggatatg ctcaagcaga gattggggat
     4801 tcaatcaatt tagaaagacc aagttctcag tatcgtcgtg gtagagttgg aaaaggtata
     4861 gcgaatacgt taacaactag tgggcaaatg ggagtagtag tggctagcta tgaaggagaa
     4921 gataaacaag tttaccaagt agctggtatc ttaattgatg ggcaatttta ccgtttgagg
     4981 atacgacgaa tcactcctaa agagtgtttt agactgcagg gctttcctga ttgggctttt
     5041 gaagctgcta gaaaagtctc tagtaatagt cagctctata aacaagctgg taatagtgta
     5101 accgttcctg tgattgccgc aatcgcaaaa aaattaaaag aaatagagga aaaagatgaa
     5161 agcattaaat agagaatcaa tactagattg tgatgaatta gaaacagaat tacatgacgc
     5221 agaaatcaaa cagctggatg aacaaatatt tttaatgcct aattatccat gtgagtttga
     5281 ggtgacattt ttagatgatt accataaaaa acataattac ccactatttt atgaatccta
     5341 tcttcaaaac attatggaat tccttgaaag tcaggatata aagaacggag ctgatgcctt
     5401 tgtagatgat aatcagaatc tagtttttgt tttatatgga caaggctatc gagccgaggg
     5461 aaaagaggga atacttacaa cccaagtaac tgtaaaagct tatgatgaag acaagcaacc
     5521 gattaacttc gcaaatttat tagattcctt aatcgtatca gaatatcaaa tggaaccgaa
     5581 tctttgggag gtttcccatg attgatctct atctaagtaa aaataaccat agaaatcaac
     5641 ttcttttgga tttcttccaa aactatggta tcgaggtatc ttgtcattca gtttctgaaa
     5701 tgacaaagga caaattaatt gagatgatga gctattcttc agattgtttc gagtttttat
     5761 ctcccaattt attacgattt aagaaccgtg acaatttaag attaacggat tttattgaaa
     5821 tgatcttaaa aaatcctgaa ctaaccatca gacttcctct tgcggtttcg aataaaagag
     5881 tttatccaaa tctgaatctg gaggaggcta gagctttatt gccaagagat acgaaacaat
     5941 tgatttacat ggcacaaaca cattatttat ctaactaaag gagaagcaat atggctgaac
     6001 gattttggga gaacttgtcc attattttgg ctgaaagaaa tattagctgg attgagttaa
     6061 ccagaaaaat gtttgcggga gagtttcact atccaagtga attgaaccgt ttgtatcaaa
     6121 agatacgcca ctacaagatg gaacaacgaa tgcctcaaag tccatgggta gaaaggattg
     6181 tgcaggtatt agatttagat tatgaagatt tatttcggag gtaactatga aaagaatcat
     6241 tccagtttat atattccaac aagtaaatgt cctattggta tctctatact tactgaaatt
     6301 gctttgtatc ggtgagttaa ctatactaca gattctctat ggtgcgtcac tcatttcttt
     6361 tttatggatg tatggccaac gcaaacaagc tcataaggtc aatatgaaat ctaggatgaa
     6421 atggcttggt attggattca ttagcctact gattataagt ctatgtttta gcctaatcca
     6481 tgctcaagga accacgaatc aagcaaactt aattggactt caacatcaag ttccttggtt
     6541 ttcattttta ttgttcttaa tcaatgcgag tatggttgaa gaatttctgt atcgagaaat
     6601 tttatggaac ttggttagaa aattagatat tcgagttgct ttgacaagtg ttttatttgc
     6661 cttagcacat catccaggaa ccattctagc ttggtgttta tatgtttcac ttgggatgtt
     6721 tttagggctt gtacgctaca aatcggactt atggggcagt atggggctac atttggtgtg
     6781 gaacctatca gtctatgtct tatttttgct ttaataatag ctgttctgtc ttacgtatgg
     6841 attaattttg aaataaaaat agcataaaaa tctagttatc cgcataaaaa ctggacttat
     6901 cacactttat caaggtcaaa accactcaat ttactactaa tttactactt atgaatgagc
     6961 tttgatacga cgatttatcc ttgaaaagtg aagatataaa gatacttcca ataaaatttg
     7021 aatatttaat aggtagacac ttcaaaaaat gaggtgtcta tttttttacc cgattttgaa
     7081 aggaagtgaa cttatgaaaa caaaaaatca agaatcaaaa ggtcgttccc cactctttaa
     7141 gaccatcaaa cattcattca gccaataaaa aagaaaggat aggtaaaaat atggaactta
     7201 aatttgtgat tcccaacatg gaaaaaacat tcggcaattt agaatttgct ggcgaggata
     7261 aagtcgttca gcgaagaatc aacggacggc taactgtctt atcaagaagc tataatctct
     7321 attctgatgt tcaaagagca gatgatattg tggtggtgct tcctgctgaa gctggcgaaa
     7381 aacatttcgg ctttgaggaa cgtgtgaagt tagtcaatcc acgtattacc gcagagggct
     7441 acaaaatcgg cactcgtggt tttacaaatt accttttaca tgctgacgac atgataaaag
     7501 aataaagaaa gagaggaaaa atgatgagat tagcaaatgg cattgtatta gataaagaca
     7561 cgacttttgg agaattgaaa ttctctgctc tacgtcgtga agtgagaatc caaaatgaag
     7621 acgggtcggt ttcagatgaa atcaaggaac gtacctatga cttaaaatcc aaaggacaag
     7681 gacgcatgat tcaagtaagt attcctgcca gcgtgccttt gaaagagttt gattataacg
     7741 cacgggtgga acttatcaat cccattgcgg acaccgttgc tactgccacc tatcaaggag
     7801 cagatgttga ctggtatatc aaggcagacg atattgtgct gacaaaggat tctagttcat
     7861 tcaaagctca accacaagca aagaaagaac cgacacaaga caaatagtcg ctaggtagaa
     7921 aggagacttt ttcgcatgaa acagcgtggt aaaaggattc gcccatctgg taaagattta
     7981 gtctttcatt ttacgatagc gtcactcctg cctgttttcc tgctggttgt cggactgttt
     8041 catgtgaaga caatccagca gatcaactgg caggatttta acctatcaca agcagataag
     8101 attgacattc cctatttaat tatcagtttc agtgtcgcaa ttcttatctg cttgctggta
     8161 gcgtttgtat tcaaacgggt tcgctatgat acggttaaac aactttacca ccgtcaaaaa
     8221 ctggcaaaga tgatacttga aaacaagtgg tatgaatctg aacaggtcaa aacagagggt
     8281 ttctttaaag atagtgctgg tcgtacaaaa aagataacct acttccctaa aatgtattat
     8341 cgacttaaaa atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac
     8401 caactcttac acttggaaaa gaaattagag agtggcttgt actgtgagct gacggataaa
     8461 gagttaaagg attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt
     8521 tctattgatg aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg
     8581 gaatatgata agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac
     8641 tttatactga cactgattga agccttgctt catacagatt caaaactgta tattcttgac
     8701 ccgaaaaatg ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa
     8761 gaagacttgc tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa
     8821 atgaagcaga tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca
     8881 cacttcttaa tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac
     8941 accgcagtta tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt
     9001 ctaatactgg cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag
     9061 tttaatttca gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc
     9121 agtgacgtac aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta
     9181 ggaacaagtg tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg
     9241 gaggaaatta aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa
     9301 gtcgcaggtg tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc
     9361 ccccgtatct aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat
     9421 cctttggtta caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga
     9481 catacgcctt tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta
     9541 aaagaaaaac gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt
     9601 acaaggcagt atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag
     9661 cagtcccttt gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt
     9721 gattatgtaa ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta
     9781 caactgaaac tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat
     9841 tatgctttag gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg
     9901 gaattgaaag gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc
     9961 tggtatgagt tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt
    10021 gccattaacg ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag
    10081 gaagaatgta tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc
    10141 aaagaggaaa aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt
    10201 tatttctgta tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa
    10261 gacgcagaag taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca
    10321 gtccgtgatt tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg
    10381 tatatccgtt ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa
    10441 gaatgggctt ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag
    10501 ccttactcct tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag
    10561 gttgcgatta aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat
    10621 gcgaaactga cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac
    10681 gtgataacaa caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt
    10741 tttatgaatt ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg
    10801 cttttagcaa tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg
    10861 attggctttt taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta
    10921 aaagacattt tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt
    10981 tgtggaatat aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg
    11041 gtagggattt ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct
    11101 atattgcgaa tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc
    11161 ccattgactt tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg
    11221 ccattcatga ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca
    11281 atcgactatg ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc
    11341 tgctcactca tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc
    11401 attccgattg tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt
    11461 taggcgaagt accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt
    11521 tagacctttc aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa
    11581 tctgtcggta cattactact ggcagatttt ctattttacg gggtggctca atcagctacc
    11641 cctatttttt atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg
    11701 tctgtggaaa aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt
    11761 acgcaaatga catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc
    11821 cctctttcca tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca
    11881 tggtttatgt ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc
    11941 attgcttatg cactgcgacc aaagctgacc tatgcaggaa aaaaagtaac gcttggcaga
    12001 aaccagccac aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa
    12061 atacattgaa aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct
    12121 tgttccttac aattactcat ttctcagtcc agaacagaaa atacaagtgc atgattcttt
    12181 cagacagctt atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga
    12241 atccagcata cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc
    12301 ggttgcctat gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa
    12361 tcaagtgaac taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc
    12421 tatgaaaagt cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa
    12481 ccataagctg atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gatttcagaa
    12541 gatggaaaag ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa
    12601 ggacgacttc ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga
    12661 gtatgagtac catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga
    12721 cttgattaag cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca
    12781 ggaagatgaa accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga
    12841 cttcccgtcc tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac
    12901 gtcaatgaat gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa
    12961 gaaagaactg aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa
    13021 tgtggcggaa gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga
    13081 atctatgtac aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa
    13141 acgtcgttgt aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc
    13201 atttggggat atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa
    13261 tgattatatt caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca
    13321 aatgctgggg gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt
    13381 ctatctgaaa cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc
    13441 gtcggctttt gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta
    13501 ttatgcggtg ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag
    13561 atggaaagaa accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga
    13621 tgagaaaaac aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga
    13681 atcactggct attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg
    13741 cttcccaatc cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat
    13801 gaaagtgatt gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca
    13861 tatcgaaagt tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga
    13921 gcagtctatc agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc
    13981 cgacaaggaa acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct
    14041 gattgtcatt agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat
    14101 tgtagattta gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat
    14161 gaagctggtt cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac
    14221 agacgacctc ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc
    14281 cactgacctt aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga
    14341 aaacaatcag aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata
    14401 tggtcgtgtc ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga
    14461 taccagacca cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata
    14521 aaatcaaact ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt
    14581 gtgattgcca tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta
    14641 gatgatacgg tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg
    14701 gatttttatg tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga
    14761 aaacaggtca tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat
    14821 gtttccaatg cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct
    14881 acagcagatt ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt
    14941 tcaacagagg gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat
    15001 gttgcctata cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat
    15061 tttgtgctgg tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa
    15121 aaaatcaatg acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt
    15181 gtcatgcccc attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg
    15241 ttttccatac aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa
    15301 agtatcggta ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc
    15361 gaagacagag aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc
    15421 attacaaaga ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg
    15481 atttccatat ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc
    15541 atctatgcta tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt
    15601 atgtcaaaac gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca
    15661 ttgattatta cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat
    15721 ccgttctttt tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg
    15781 ggcgatttaa tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt
    15841 gtgatgagaa aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt
    15901 ggacgttcca tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag
    15961 tcgggttcgg ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa
    16021 aaatcaacac ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac
    16081 agaatggtag acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca
    16141 agatatgcag tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt
    16201 agtatttctc aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg
    16261 cgaaaaacca ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct
    16321 gcttcttctg ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc
    16381 tcaaaacagt ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt
    16441 ccagcagtta agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa
    16501 gaaaaaaccg ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt
    16561 ccaatcacaa aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt
    16621 agaccaccaa tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa
    16681 ctttagtgat tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg
    16741 ccattttatt ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga
    16801 atgtttccgc agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg
    16861 gcgttgaaga atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg
    16921 cggaagatgt tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag
    16981 aagaatccat taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc
    17041 tcagtgtaga tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt
    17101 atgtggctaa tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt
    17161 attcaggtgg cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct
    17221 ggcgatacaa ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa
    17281 cagagtttga tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct
    17341 ggcgatacgt ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac
    17401 aatggacgta tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg
    17461 tgacccagca tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta
    17521 cctataacgc tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt
    17581 ttcatgcagg cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt
    17641 tagtgggagc aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa
    17701 aaatcagaat aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt
    17761 caatcctcat aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt
    17821 tgcgatattc aagcacttta cagctataga tactcatact attcacgaaa caactatcat
    17881 agaaaaggaa tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt
    17941 ctactattca tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg
    18001 ctatctgaca gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt
    18061 atcgtcttct gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt
    18121 taatgtaacc tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca
    18181 ctctgcttat atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa
    18241 tccgaccatt accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga
    18301 ggggacggtt gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa
    18361 gctctatcct acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa
    18421 accaatcgga aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga
    18481 taatcaagtc acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca
    18541 ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata
    18601 acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat
    18661 tggagattcc tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga
    18721 gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag tgggaacaaa
    18781 taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa aataccttta
    18841 tcatgtgatt ctaaagtatc cggagaatat ctgtatgctt tgtatgccta tggttatgca
    18901 taaaaatccc agtgataaga gtatttatca ctgggatttt tatgcccttt tgggcttttg
    18961 aatggaggaa aatcacatga aaattattaa tattggagtt ttagctcatg ttgatgcggg
    19021 aaaaactacc ttaacagaaa gcttattata taacagtgga gcgattacag aattaggaag
    19081 cgtggacaga ggtacaacga aaacggataa tacgctttta gaacgtcaga gaggaattac
    19141 aattcagaca ggaataacct cttttcagtg ggaaaatacg aaggtgaaca tcatagacac
    19201 gccaggacat atggatttct tagcagaagt atatcgttca ttatcagttt tagatggggc
    19261 aattctactg atttctgcaa aagatggcgt acaagcacaa actcgtatat tatttcatgc
    19321 acttaggaaa atggggattc ccacaatctt ttttatcaat aagattgacc aaaatggaat
    19381 tgatttatca acggtttatc aggatattaa agagaaactt tctgccgaaa ttgtaatcaa
    19441 acagaaggta gaactgtatc ctaatatgtg tgtgacgaac tttaccgaat ctgaacaatg
    19501 ggatacggta atagagggaa acgatgacct tttagagaaa tatatgtccg gtaaatcatt
    19561 agaagcattg gaactcgaac aagaggaaag cataagattt cagaattgtt ctctgttccc
    19621 tgtttatcac ggaagtgcaa aaaacaatat agggattgat aaccttatag aagtgattac
    19681 gaataaattt tattcatcaa cacatcgagg tcagtctgaa ctttgcggaa aagttttcaa
    19741 aattgagtat tcggaaaaaa gacagcgtct tgcatatata cgtctttata gtggcgtact
    19801 gcatttgcga gattcggtta gaatatcgga aaaggaaaaa ataaaaatta cagaaatgta
    19861 tacttcaata aatggtgaat tatgtaaaat cgataaggct tattccgggg aaattgttat
    19921 tttgcagaat gagtttttga agttaaatag tgttcttgga gatacaaagc tattgccaca
    19981 gagagagaga attgaaaatc ccctccctct gctgcaaacg actgttgaac cgagcaaacc
    20041 tcaacaaagg gaaatgttac ttgatgcact tttagaaatc tccgacagtg acccgcttct
    20101 gcgatattat gtggattctg cgacacatga aatcatactt tctttcttag ggaaagtaca
    20161 aatggaagtg acttgtgctc tgctgcaaga aaagtatcat gtggagatag aaataaaaga
    20221 gcctacagtc atttatatgg aaagaccgtt aaaaaaagca gagtatacca ttcacatcga
    20281 agttccaccg aatcctttct gggcttccat tggtctatct gtagcacagc ttccattagg
    20341 gagcggagta cagtatgaga gctcggtttc tcttggatac ttaaatcaat cgtttcaaaa
    20401 tgcagttatg gaggggatac gctatggctg tgaacaagga ttgtatggtt ggaatgtgac
    20461 ggactgtaaa atctgtttta agtatggctt atactatagc cctgttagta ccccagcaga
    20521 ttttcggatg cttgctccta ttgtattgga acaagtctta aaaaaagctg gaacagaatt
    20581 gttagagcca tatcttagtt ttaaaattta tgcgccacag gaatatcttt cacgagcata
    20641 caccgatgct cctaaatatt gtgcgaacat cgtagacact caattgaaaa ataatgaggt
    20701 cattcttagt ggagaaatcc ctgctcggtg tattcaagaa tatcgtagtg atttaacttt
    20761 ctttacaaat ggacgtagtg tttgtttaac agagttaaaa gggtaccatg ttactaccgg
    20821 tgaacctgtt tgccagcccc gtcgtccaaa tagtcggata gataaagtac gatatatgtt
    20881 caataaaata acttagtgta ttttatgttg ttatataaat atggtttctt gttaaataag
    20941 atgaaatatt ttttaataaa gatttgaatt aaagtgtaaa ggaggagata gttattataa
    21001 actacaagtg gatattgtgt cctgtatgtg gaaataaaac acgattaaag ataagggaag
    21061 atactgaatt aaaaaaattc cccctctatt gtccgaaatg cagacaagaa aatttaattg
    21121 aaataaagca gttcaaagta actgtgatta cagagccaga cgcaaagacg cagagccgat
    21181 aaaatgagat taatacaatc tcattttatc ggctctttcc gttatgtatg gattctttta
    21241 attagtcttc gatgtttctt gcttcgttga taccgctggc taaagattcc attaaggata
    21301 gttctttgtc tgtaaagcta tccatgtatt tctctatctg taatcgtcgg gtgcttttta
    21361 ccaagttatt agcaggtagg ggtcccgagc gcctacgagg aatttgtatc gataagaaat
    21421 agatttaaaa atttcgctgt tattttgtac atttaacttg acggtgacat ctctctattg
    21481 tgagttatta gtggtacagt tttcaaccgt tttaattata aaaaagtggt gcatttttaa
    21541 attggcacaa acaggtaacg gttattgcag gtgtatttct tatctatggg tttaacatgg
    21601 attttatcat taaaatcatg agtattgtcc gagagtgatt ggtcttgcgt atggttaacc
    21661 ctaaagttat ggaaataaga cttagaagca aacttaagag tgtgttgatt gtgcattatc
    21721 ttaaaatttt gtataatagg aattgaagtt aaattagatg ctaaaaattt gtaattaaga
    21781 aggagggatt cgtcatgttg gtattccaaa tgcggaatgt agataaaaca tctactgttt
    21841 tgaaacagac taaaaacagt gattacgcag ataaataaat acgttagatt aattcctacc
    21901 agtgactaat cttatgactt tttaaacaga taactaaaat tacaaacaaa tcgtttaact
    21961 tctgtattta tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa
    22021 tattctcaaa actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat
    22081 ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa
    22141 ctggctaaaa taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta
    22201 tcgtcagaaa aattaaaact gaacattcgt gtcactttaa ttcaccaaga tattctacag
    22261 tttcaattcc ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc
    22321 acacaaatta ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta tctgattgtt
    22381 gaagaaggat tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac
    22441 actcaagtct cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca
    22501 aaagtaaaca gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat
    22561 tggaagctat atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt
    22621 actaaaaatc agtttcatca agcaatgaaa cacgccaaag taaacaattt aagtaccgtt
    22681 acttatgagc aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa
    22741 ttctatgagt cgcttttgta aatttggaaa gttacacgtt actaaaggga atgtagataa
    22801 attattaggt atactactga cagcttccaa ggagctaaag aggtccctag cgcctacggg
    22861 gaatttgtat cgataaggaa tagatttaaa aatttcgctg ttattttgta caataaggat
    22921 aaatttgaat ggtaccataa acgaccgttt atggtacctt ttcattttcc tgctttttct
    22981 aaatgttttt taagtaaatc aagtaccaaa atccgttcct ttttcatagt tcctatatag
    23041 ttatacttaa tgagttatgg tacatttaaa ttataaaatt aaggaggttt ttttatgatt
    23101 tttggctatg ctcgagtgag tacggatgat caaaatctta gtttacaaat tgatgcactt
    23161 actcattatg gaattgataa attatttcaa gaaaaagtaa ctggtgcgaa aaaagaccga
    23221 ccgcaattag aagaaatgat caacctacta cgtgaaggag attctgttgt catttacaag
    23281 ttagatcgaa tttcacgatc aactaaacat ttgattgaac tttctgaatt atttgaagaa
    23341 cttagtgtca attttatatc tattcaagat aacgtagata cttcaacgtc tatgggaaga
    23401 ttctttttcc gagttatggc tagtttagca gaactggaac gggatattat tattgaacga
    23461 actaactctg gtcttaaggc agccagagtc cgaggaaaaa aagggggccg tccaagtaaa
    23521 ggtaagctat caattgattt agctttaaaa atgtatgaca gcaaagagta ttctattcgt
    23581 caaattcttg atgcctctaa attaagcaaa acaacctttt accgttacct caataaaagg
    23641 aatgcttaag atatggctat gaaaagaatt ttaactactt cacagcgtga acaacttctt
    23701 tctgtagacc acttatcaga agaggatttt aaagcgtatt ttagtttttc tgattatgat
    23761 ctggaggtta ttaatcaaca ccgtggaaag gtcaataaac taggatttgc gatacaactt
    23821 tgtttggccc ggtatcctgg gtgttcttta agtaattggc cgattaaatc aaccagacta
    23881 acttcttatg tgagtcgaca gctccatctt gatgcaattg atttaaattc atatgatcat
    23941 agaaatacac gtgcaaatca cttcaacgag atcttagaag tattcaacta tcatcgattc
    24001 ggtagtgcta atacacaaaa acagttaata gaatatttaa ttgaactagc tttagaaaat
    24061 gatgactcta tctatctaat gaaaaaaaca attgatttct taactcgaaa aagaattatt
    24121 tttccatcta tagctacact tgaagacatt ataagccgct gtcgagataa agcagaaaac
    24181 aacttatttt caatattact ctgttcatta acagatatac aaattgaaaa actagagagt
    24241 ttgtttcaaa tttatgaaga gacgaaaata actaaactcg cttggctaaa agacattcca
    24301 ggtaaggcaa atccagaaag ctttatgagt atttgtaaaa aagtggaagt gattgcttcc
    24361 atgggactcg ggacaattaa tgtctcccat attaatcgga acaggtttct tcagctagct
    24421 agactagggg aaaattatga tgcatatgac ttctcccgtt ttgagcttga aaaaagatac
    24481 tctttactta ttgctttttt agtcaatcat catcaatatc tgatcgatca actgattgag
    24541 attaatgacc gcattttagc aagtattaaa cgcaaaggga cacgtgattc acaagaacag
    24601 ttaaaagaaa aaggaaaatt ggctactaaa aaattggaac attatgcttc tttaattgat
    24661 gctcttcact ttgcaaaaga taatgatagt aatccttttg acgaaattga acgaatcatg
    24721 ccttgggaag atttagtaca agatggagaa gaagctaaaa aaattacagg taataaaaat
    24781 catggctatt tagaaatggt tcgaaataaa gctaattacc tccgaagata cacgccaatg
    24841 ttattgagga ccctttcgtt caaagcaact ccggcagcaa atccagtcct catggcccta
    24901 actcaactaa ctgatttaca caatagtggt aaaagaaaaa taccggcaga tacttctact
    24961 gattttgtga gtaaaaaatg gaaaagcctt gttcggccag aagaggggaa aatagatcgg
    25021 tcttactatg agttagtagc tttcaccgag ctaaagaaca atattcgatc aggagatatt
    25081 tcagttgaag gaagtatgat ccatcgaaat attgatgatt acttagttga tttatctgct
    25141 tgtattgatt cagaaactat tccagacacg tttgaggact atttaaagga tcgggaaata
    25201 attttagatt tacagcttca attttattcg acagttgata agagaatttc aagagcaaac
    25261 cttaaaaagt tggaaaaagt tacacctagc gaagcagaaa tatatagaaa aaaactttat
    25321 tcaataattc ctaagataag gcttagtgat cttttaattg aggtggacag ttggaccaac
    25381 ttttcacaag aatttagtca tgattctaca gggaaaccgc cgagtgaaca agaaagaaaa
    25441 attatttttg ctgctttgct gggtttaggg atgaatattg gtcttgaaaa aatggcccaa
    25501 tcaactcctg gaatttctta ttctcagtta gccaatgcca aacaatggcg cttttataaa
    25561 gaagctctga ctcgtgctca atctgttttg gttaattatc agttaaagct tcctgttgca
    25621 gacttttggg gtgaaggaaa aaccactgct tcagacggaa tgcgcgtccc agtgggcgtc
    25681 tcagctctaa aatccgatgt taatccacat tacaaaagta tggaaaaagg agctacaatg
    25741 attcgatcaa taaatgatag gcatacgact catcatatcg aggttgcttc aactaataca
    25801 agggaagcta ctcataccct tgatggccta ctttatcatg aaacagatct agatattgag
    25861 gaacatttta ctgatacaaa tgggtattct gatcaggtgt ttggaatgac cgcattacta
    25921 ggctttgatt ttgaacctcg catcagaaat ataaaaaaat cacaattatt ttctatcaaa
    25981 tcaccttcct actaccctaa cttatcagaa gatataagcg gaaaaatcaa tgtaaaaatt
    26041 attgaagaaa actatgatga aattaaacga atcgcctatt cgattcaaac aggaaaagta
    26101 tctagttctt tactattagg aaagctaggc tcatacgcac gtaagaatag agtagctctt
    26161 gcactgagag aactaggtcg cattgaaaag agcattttta tgatagatta tattacagat
    26221 agtgagctac ggcgaaggat cactcatgga ctaaataaga cagaagcgat taatgcttta
    26281 gctagagaac tattttttgg gcgacgcgga aaatttatgg agcgcgatat tcgccgacaa
    26341 cttcaaagtg ctagtgcgct taatgtgtta ataaatgcaa taagtatatg gaacgccgtc
    26401 tacttacaag cagcttataa ttatctcgtc aaaatagatc ccgaagtaac taagtatatg
    26461 aagcatgtat ctcctattaa ttgggagcat atcacttttc ttggagagta taaatttgac
    26521 ttgttatcta ttcctaaaca cttaagagaa ttgaatataa aaaataaata ggccttgaaa
    26581 cattggttta gtgggaattt gtacccctta tcgatacaaa ttcccactaa gcgctcggga
    26641 ccccaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    26701 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    26761 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    26821 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    26881 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    26941 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    27001 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    27061 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    27121 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    27181 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    27241 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    27301 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    27361 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    27421 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    27481 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    27541 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    27601 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    27661 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    27721 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    27781 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    27841 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    27901 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    27961 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    28021 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    28081 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    28141 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    28201 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    28261 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    28321 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    28381 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    28441 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    28501 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    28561 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    28621 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    28681 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    28741 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    28801 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    28861 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    28921 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    28981 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    29041 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    29101 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    29161 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    29221 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    29281 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    29341 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    29401 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    29461 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    29521 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    29581 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    29641 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    29701 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    29761 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    29821 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    29881 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    29941 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    30001 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    30061 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    30121 aaatataaaa agataattag aaatttatac tttgtttatt tataaaaaaa ctaaatgaat
    30181 tgattttaaa gaaataaaat gctaacatat atagtagatg ttagtatttt atttctaaga
    30241 aaggagaatg atatggttga taaaagagag aaactgatga actctttcaa tcagtatggt
    30301 tttttaactt ttaaacaagt aatagatgaa aatttacact acaaaacctt attaaaaatg
    30361 gttgcagaag gaaaaatcga tgctgaagaa aaagggttat atcgcttacc tgatatttat
    30421 ttagatgagt ggtttgtcct tcagtatcga tttccaaagg gaatcttttc tttggagaca
    30481 gcactttggt tacatggttt atctttgact atccctttta acatgacgat gagttttcct
    30541 tatggtacga ataccaaaaa cattaaggaa gcagatatat gtcctattat cttacgctct
    30601 cactatagtg aaggaattat tgaaatagag cgccttcctg gtcaatttat taaagtttat
    30661 gaagttgagc gagttttggt tgaatgtcta agaccagttc atcaggtgga tcttcaaatt
    30721 attgcaccag cgtttaaaaa atattttcaa caaaataaaa ttcatttaca caaattattt
    30781 tattatgccc agctatttaa agtaactgat aagttacaat cttatacgga ggtactatct
    30841 taatgttttc aaatgcgaat agctttaaag caaaaatcaa aaacatttca aaagataagg
    30901 gaattccagc tcaacaagta caacaacatt atttaattga gcaagtgtta aagctgattt
    30961 ctactagttc ttatagagat tccttcattg taaaaggagg gtatctaata ggtcaaatga
    31021 ttggactaga taagcgaacc acaatggatt tagatgtcac tctgaaggga accgaaatga
    31081 gcagagaaaa tttgattcat atctttgaag agattctttg ttctaatact gatggatttt
    31141 cattttcagt agataagcta gaacctattc gtcaagatga tgaatatgga ggattttcat
    31201 taaaattaaa tgcaactttt gatacattaa aagaggttgt ttttattgat attactactg
    31261 gtgataaaat cacaccaaga gaaattactt attcaatgac ttctatcttt actaatgaaa
    31321 gcatcaagat atggacatat aatctagaga ctgtacttgc tgaaaagtta gaaacaatca
    31381 tcagtagggg actagcttcg acgcgtccac gtgatcgata tgatcttttc accttgtata
    31441 aacttagaaa agaagagatt aatcttgaag tattaaaaaa tgcacttgag aatacggcag
    31501 aaaaacgtaa aagtaaagat actatttata attgggaaga acaagtgaga ggaattgaaa
    31561 tttctgatta tcagaaagag ctatggattc gttatcaacg ccaatttaag tatgctaaag
    31621 atatctcatt tgataactct gttcaggtca ttagggaaat tatgcaacaa atattttagt
    31681 acaaaagtaa ctcattagta aagcagtgag ttgctttttt tattccaata actccaaaaa
    31741 tgtgataaaa atttcaacta ctcttatcta taataaagct acctgttctt tgaaaattga
    31801 atccactccg tcttgattag cgtgcctgtg taagtaggga ctgagagtat ttccctgtga
    31861 agggcaactg gcacaagacg tgtgtgagaa ttttctaaca gacacggagt ttatcgttac
    31921 cagacttaaa cgatgcgaca aactagataa aggagttaat catgaaggta gtaaacttgt
    31981 atgatttgaa acaaatggga aataaaggtg gttgtaccat ccaattgatt catcactttc
    32041 cttttggtat gggcttagga catctcaaaa aagactacat tgaatttaaa cgtgttggta
    32101 tcgttgatgg gaaggcagta gaagtcactc ttcgagaacc ttattcgaga gatctactgc
    32161 aggttgtcaa gtcgattaag caacgtcaga aattgatagc ttatcgttat aaagaaggaa
    32221 agctgctatt tgtgaagaag gaggcatcag atgtcctctg aacaacagga acgaatggca
    32281 gttcaatatg cggagcgtag tcttttattt actgtcaaaa gtctcttaaa aattctagaa
    32341 tggtctagac gtcaggcttt agcacaggat tccgcctata agataggggt gcagaaatta
    32401 gaagaattgc tacaatctcc ttattcgatt gatacgatta atctgaaaaa agatttttta
    32461 gacaaaccaa ttgatataga gaaatttaaa gcttttttag aaaaagaaga gattccttta
    32521 gccatcgctt ggcaagggga ttctctacat ttctacacga aagaccgttc gattctggac
    32581 aatcatttag accatctgtt agaaaaaatg gttaatgatc cggagaaatt agctgatttt
    32641 accatggata agtcattaga cgatgcaatt gatgaggcga aatcccaaat tacctttaga
    32701 caagaagggg ccgtcaaaca gaaagagatg gtgagatgat gtacagtgga aagaaattcc
    32761 tactattttc actgttaggt atcttactag gctatctttt tcatcgtttg acgcttttgt
    32821 atgattccta tactggaaat acattagata aatggactca tcttctgatg gaaggtcaag
    32881 atgaagttct tcagtcgcca tggaatgttt cctttactgg aaaatccagt gctttttttc
    32941 tactaggctt tgtgatgatg ttgctggttt atctttattt agagactggc aaaaaacaat
    33001 accgagaagg ggtagaatac gggagcgccc gttttggaac tctaaaagaa aagaagctct
    33061 tttacggtaa ggaattttct catgatacga tcttagctca agatgttcgt ttgacattat
    33121 tagataaaaa acccccccaa tatgatagaa ataagaatat tgcggtgatc ggaggttcag
    33181 gaagtgggaa gacatttcgc tttgtgaaac ctaatcttat tcagatgaat agttctaata
    33241 ttgtagtgga tcctaaagat cacttggccg aaaaaacagg caaactcttt ttagaacatg
    33301 gctatcaagt aaaggtgcta gatttagtca atatgaagaa ctcagatggc ttcaatcctt
    33361 ttcgctatat agagacagaa aatgatttga atcgcatgct gacggtttat tttaataaca
    33421 ccaaaggctc tggctcccga agtgacccat tttgggatga agcttctatg actttggttc
    33481 gagctttagc ctcttacttg gtcgatttct ataatccacc caaaacaaga gaacagctca
    33541 ttgaagagag tcgtttgagt caaaaagaat accagaactt gttgaaacgt caaaaaaaag
    33601 aagtggaaga gcgaaaaaaa cgaggacgtt atccaagttt tgctgaaatc tcaaaactca
    33661 ttaaacactt atctaagggt gaaaaccaag aaaaaagtgt cttagaaatt ctatttgaaa
    33721 attatgctaa aaagtatggc actgaaaatt ttaccatgcg aaattgggca gatttccaaa
    33781 attataagga taagactctg gattctgtta tagctgtaac cactgctaaa tttgccctct
    33841 tcaatattca aagtgtcatg gatttgacca aaagagatac ccttgatatg aagacatggg
    33901 gccaggaaaa atcaatggtt tacttagtta tcccagataa cgatagtacc tttcgctttc
    33961 tttcagccct ctttttttca accgtatttc aaaccctaac aagacaagca gatattgatt
    34021 ttaagggtca attgcctctt catgtgagag tctacttaga tgagttcgca aatataggag
    34081 aaatcccaga ttttgctgaa caaacctcaa cagtccgttc tcgaaatatg agtctcgttc
    34141 ccattcttca aaatattgcc caacttcaag ggctctataa agaaaaagaa gcttggaaaa
    34201 ccattttggg gaactgtgat agcttagtct acttaggtgg gaatgatgaa gataccttta
    34261 aatttatgag tggcttactc ggtaaacaaa ccattgatgt tcgaaatact agtcgttcct
    34321 ttggccagac aggttcagga tccctttctc atcaaaagat tgctcgtgat ttaatgacac
    34381 ctgatgaggt cggaaatatg aaacggcatg aatgcttggt tcgaattgcc aatatgcctg
    34441 tctttaaaag caaaaaatac aattccacta agcatccaaa ctggaaatac ctagccaatc
    34501 aagaaaccga tgaacggtgg tggaactatc aaatcaatcc tttgaatcaa agacaagaaa
    34561 atcatcttga aggccttaga attcgtgatt taacttttga atctagttta aaataaaaat
    34621 agaaaagagg aaatagatga ttacgcattt taaaggtttt gtttatggag tagacgcaag
    34681 tgctatgttt gcacaagcta tgtctttgtt acagaagggt ttgattgcgg ttggtgcctt
    34741 tctcgttgtt gtggggattg tcaatcttgc aaccaacatt aaagatggtg gaccaggtgt
    34801 tcggaatgcc attctggaaa ttgtcggtgg tgttatggta ggggctgctg gagcctttgt
    34861 aactcaaatt tcaatttagg aggataaaca atgacatgaa tcttagttta gtctcaccct
    34921 ttgtttacct tgcatctgaa aaaatatcag ctgaaaattt atttgaaggg tttaatgtag
    34981 atttacaatc tacggtagat ctgattaaat ccctatctag ctacaatcca acagtttgga
    35041 cttatatgtc tagtattact aaaagtgtca tgcagcctct tggagttgcg attttatcag
    35101 ttgttctcat cttagaattt tcgaagatgg caaagaaaat tgctaactca ggaggagcga
    35161 tgacctttga agcattagcg ccgatgttga ttagttatat catggtcgca gtcgtgatta
    35221 ccaatactac cgttattgta gaagccatca tcgggattgc gagtcacgcc attgaacaag
    35281 tggcctcaat tgtggctcac ggtggggcaa agtatgatac catctctgga ttaaaaggtt
    35341 caggatttat tggccggatg attgtgggct ttttcgccct cctcatttgg ctagttcgga
    35401 tagtaagtgc agccatggtt aaccttttgg tatctattcg atttattcaa ctctacctta
    35461 tgattccatt tgcccctctt acgattccaa catttttaag tgatgaatgg aagtctattg
    35521 gtattggcta tttaaaaaat attatggttt atgcggtaca aggggttctc atttttctga
    35581 ttgtttctct tgttccttta tttgaatctg ctgggaaaat agctgtttca aatggtgcag
    35641 gagtcttgca atcacttgcg attatgtttg gtagtttggt acaagctatc ttactgatta
    35701 ttgccctcgt tggttctcaa cgtacggctc gctcaatctt aggtatgtaa ttagataaag
    35761 gctaggaagt gattgcttct tagccttttt agaaaggaaa gtcatgaata cacgtgtctt
    35821 taaagacatc tcaaaatacc aacacagggc ttggttaggt ttcaccacaa gacaaatcat
    35881 ctttgtttta ccagccttta ttgtcacaat tattgttttg ggcttgaatc tctttttctg
    35941 gcaatttgga gattggtttg tttacggttt tgtgtttgct tttaccatcc ccctcatgct
    36001 ttttggagtc tataaaccca atgatttata ttttgaacat tatttgaaat accgtcttca
    36061 ttttgaacta acggttcccc tacgcacaat tacaggaaag aaaggacctg aacatgaaaa
    36121 gaaaatcaaa tacattaaag aaacaaaaaa cttcaatgac taatcagaaa gaagtagtta
    36181 aaggaaaaaa agaggaagtg ttaccatcga cggctaatac tctttcctat caagccctgt
    36241 atcaaaatgg tctgatgcag gtaaaagaag attatttctc acaaagctat ttacttggtg
    36301 atgtcaatta ccagactgtt ggtttagaag ataagggcgc aatcattgag aagtattctg
    36361 atttgattaa ctccctagac gaccaaacca acttccaatt gactatcttt aataaaagat
    36421 tgaatttaga aaagtttaga caaagtgttt tgtatgagga aaaagaagat gggtatgata
    36481 gctatcgtaa agaattgaat cggatgatga atcagaattt agacagtggt gaaaataact
    36541 tttcagctgt gaaactgatt agctttggta gaaaggattc taatcccaaa caagcctatc
    36601 gttccttgtc tcaaattgga gaatatttca agagtggttt ctcagaaatt gatgctcgat
    36661 ttgaatcttt ggctggagaa gaacgggtga acttgctggc agatatgctt agaggagaac
    36721 accatcttcc tttttcttac cgtgatttaa cgagatctgg tcagacaact cgtcacttca
    36781 tagcacctaa tctcttggat tttaaaaaca agaattacct acaaatcaat gaccgcttat
    36841 tgcagattgt ctatgtcaga gactacggta tggaattagg agatcagttt atttgagacc
    36901 tcatgcaagg agatttggaa ttgattgtga gcctccatgc tcaaagttcg accaaggcgg
    36961 atgctatgaa gaaactacga acaaagaaga ccttgatgga atcccaaaag attggggaac
    37021 aacaaaaact tgctcgtaca ggtatctatt tggaaaaagt aggtcatgta ttagaaagca
    37081 atatcgatga agctgaggaa ctcttaaaaa ccatgaccga gacaggagat aaactatttc
    37141 aaacagtatt cttgattggt gtttttggtc aggatgaaga agaacttaaa caagctctag
    37201 atacgattca acaagtggcc ggctcaaatg acctaatgat tgataaacta ccatatatgc
    37261 aagaagcagc ctttaatagt ttgctgccat ttggttgtga ttttttagag ggagtatcac
    37321 ggagtttatt aacatccaat atagcagtga actctccatg gacttcagta gacttacaag
    37381 accgtagtgg aaaatattac ggtatcaatc aaatctcaag caatattatt accattgatc
    37441 gcagcctatt aaatacaccg tctggtctga ttttagggac atctggagct gggaaaggga
    37501 tggcaaccaa gcatgaaatt atcacgaccc aaatcaagga atctggtgaa aatactgaaa
    37561 ttatcatcgt ggatccagaa gcagaataca gtgtcattgg acgagctttt ggtggagaaa
    37621 tgattgatat tgcgcccgat tcccaaactt atctcaatgt ccttgatttg tctgaggaaa
    37681 atatggatga agatcctgta aaggtaaaat cagaatttct tttatccttt atcggcaagt
    37741 tattggatag aaaaatggat ggaagagaaa aatcgattat cgaccgagtc acaagactca
    37801 cctatcagtc atttaaagag ccttctttgg aagaatgggt ctttgtcttg agccaacaac
    37861 cagaagaaga agcgcagaat ttggcacttg atatggaact gtatgtcgaa ggttctcttg
    37921 atattttttc tcataagacc aatattcaga caggatctaa tttcttgatt tataacgtta
    37981 agaagttagg agatgagctg aaacaaatcg cccttatggt tgtttttgat cagatatgga
    38041 atcgtgtcgt tcggaatcaa aaattaggga agaagacctg gatttatttt gatgaaatgc
    38101 agcttctctt attagataaa tatgccagtg atttcttctt taaattgtgg agtcgtgtca
    38161 gaaaatatgg agccagtctg actggaataa ctcaaaacgt cgaaacctta ttgttagatc
    38221 caaatggtag acggattatt gcaaatagtg aatttatgat tcttctcaag caagcaaaaa
    38281 atgaccgaga agaactggtt caactcttag gcttgtcaaa agaactcgaa aaatacctag
    38341 tcaatccaga aaaaggagca ggactgataa aagctggttc agttgtcgta ccatttaaaa
    38401 ataagattcc tcaaggtact caattgtttg atattatgag tacggatcct gataaaatgg
    38461 cttctaatta aggggaaggt aaatgaagga taaaagagaa atcatacgtg cccgaaaagc
    38521 atttagaaga agtctaaaag atgagaagaa attcttgaaa caaggaaaga aggaggtgag
    38581 gaaacagaaa aaagattccg ctgtactgga tgaaaaagca tggaaaaaag agataaaaga
    38641 aaagctagag gagatgagag aagcttcaaa ggagagagta aaacaagcaa atgaagacta
    38701 caatcatatt cttcaaaata gtcctccatc ttttttgaat cgtaaagaat taagagacag
    38761 acgattacct catgctagga aacgattgaa aatagccaag aagcaattta gagaagccaa
    38821 ggtagaagca aaagaagaaa gaaaagagag tcgtaaagaa agaaaaacca atcaaaaatt
    38881 tctctacggt caggaatcga aacaaaaatc taattttttc tttcaaggga agagtttaga
    38941 agaattaaaa gctaagaaag aagtcaaggc tgctaaagaa aatttaaaat ctactaaaca
    39001 agcctataag tacaaaaaag tcagtaggaa agccaaaact tttctttatg tccttggacg
    39061 tgaaggtgga gagttagctt cagaaaatga agatttagaa ggctatcgca cacttcaaga
    39121 gaccattaga aaagggaaac gctacagtcg gctttcttat aatcttggaa aagctagtgt
    39181 caaaacagga caagcaacag gtcgttttac caagaaaaga ctgaccaaca caaaagagcg
    39241 ataccatcat tttaaggatg gaaaaggatg gaaactagca aaagataacc caagttcctt
    39301 taagaatcgg tttcgaaaat taaagaaaca aggtctttca agtgtccaaa atatctatca
    39361 aaaactaaaa gcagcctttt ccttctttac atttgcggct ggaaatcctg caacatggat
    39421 agttggagga atagtctttc ttcttttact tatgatgagc ttcttcttag gattttcatc
    39481 tgctagtttg attcaacaag atgaatttga attaacaaaa gcttataccc acctaacttg
    39541 ggaagatgca gaacatactc gcacaaatga caaaggaatt acctattaca caaaagttga
    39601 tgatgtgatg gggtatatga actttaaatt ccatgactat gagttacaga aaccagttca
    39661 cttatttagt tcagaaactt acaaggatta tctgtctact ttgtggcatg atttaaacga
    39721 tggtgatgat ttgaaatcca tgcaagacct ctatgaaact cctaagtata aactatcgaa
    39781 agacgatcaa gaggaaataa aggaactaaa agaagaaggt gtgtatgctt ccatgcagga
    39841 attagacaat ccatttgagg gacaaagcaa cgaagatagt ctaaccatga cttatcgtta
    39901 tggatactat gatttagatg ggaaacctac tcttcaggag tacatcctac tagaagcaaa
    39961 ggctcaccaa acgattgtcg caccaatgga tgcagttgta tctctagatg gtgacaatat
    40021 tattctcact aacggaaaag gagagaatga gagtcgatta accttgtatt ctattcataa
    40081 tggccgtgcg attgagggga caagagtcct aacgggtgat attattggtg aaacaccaga
    40141 cgatacaggt ttgaaagttt cctatcaaaa gtataagaac aagaaagaaa aattggtgta
    40201 tgtcaatccg caattttatt ttccaaaagt cattcaactt cagaccacta tcttacctgc
    40261 cattggtcag tttggtgggg atgagtttga acgagcaaaa catatttatg attttttgaa
    40321 atctcaaggc gtaagtcccc aagccattgc ggctatttta ggaaattggt ctgtagagtc
    40381 ttctattaat ccaaaacgag ctgaaggaga ttatttatct cctccagttg gcgctaccga
    40441 ttcctcatgg gatgatgaaa gctggttagc gattggaggt ccagccattt atagtggtgc
    40501 ttatcctaat attcttcata gaggtttggg gttagggcaa tggacggata cttcagatgg
    40561 ttcaacacgt tatacagctt tattgaatta tgcacatagc aaaaataaga agtggtatga
    40621 tttagacctc caacttgatt ttatgcttca tggggatagt ccttactacc aaagttggtt
    40681 aaaagatttc tttaaaaata cgggcagtgc agccaatctc gcccaactct tcctcaccta
    40741 ttgggaggga aattctggtg acaaattact ggaaagacaa accagagcaa cggaatggta
    40801 ttaccaaatt gaaaaaggct tcagccaaac aaatggagga caggcaaaaa gtgacccaca
    40861 atcccttgaa ggggttcgtg gggacttgta tgatcattct gttcctggtg gtggagatgg
    40921 tatggcctat gcctatggac aatgtacatg gggtgttgcg gctcgtatga atcaattagg
    40981 cttaaaatta aaaggaagta atggagagaa gatttcaatc attaatacca tgggaaatgg
    41041 tcaggactgg gttgcgacag cttcaagtct tggtggggaa actggctcta caccaagagc
    41101 aggtgctatt gtttcttttg tgggaggtac acatggcaca ccagcagact atggtcatgt
    41161 agcttttgta ggtgcgagac gtttctaact gaaaaggtta gacacgttct
//
